CN117298443A - IABP control method and device - Google Patents
IABP control method and device Download PDFInfo
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- CN117298443A CN117298443A CN202311590168.8A CN202311590168A CN117298443A CN 117298443 A CN117298443 A CN 117298443A CN 202311590168 A CN202311590168 A CN 202311590168A CN 117298443 A CN117298443 A CN 117298443A
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- 238000000034 method Methods 0.000 title claims abstract description 36
- 238000004458 analytical method Methods 0.000 claims abstract description 83
- 230000036772 blood pressure Effects 0.000 claims abstract description 62
- 238000013507 mapping Methods 0.000 claims abstract description 31
- 210000001765 aortic valve Anatomy 0.000 claims abstract description 18
- 230000000747 cardiac effect Effects 0.000 claims description 72
- 230000008859 change Effects 0.000 claims description 69
- 230000004872 arterial blood pressure Effects 0.000 claims description 44
- 238000004891 communication Methods 0.000 claims description 18
- 238000004590 computer program Methods 0.000 claims description 11
- 238000010586 diagram Methods 0.000 description 7
- 230000006872 improvement Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 230000009471 action Effects 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000000709 aorta Anatomy 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 238000013528 artificial neural network Methods 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 238000000802 evaporation-induced self-assembly Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 230000000004 hemodynamic effect Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/135—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
- A61M60/139—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/295—Balloon pumps for circulatory assistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/497—Details relating to driving for balloon pumps for circulatory assistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/515—Regulation using real-time patient data
- A61M60/531—Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
Abstract
The embodiment of the application provides an IABP control method and device, which relate to the technical field of medical appliances, and the method comprises the following steps: determining an intersection between the global valley set and the local valley set obtained by analysis, and determining signal points in the determined intersection as signal points representing the opening of the active valve as valve opening points; determining a signal point representing aortic valve closure as a valve closure point based on the amplitude variation characteristic of each signal point in the second target signal segment between every two adjacent mapping points in the blood pressure variation signal; determining a physiological performance parameter of the heart based on the signal parameter information of the valve opening point and the signal parameter information of the valve closing point, determining a control parameter of the IABP based on the physiological performance parameter, and controlling the IABP according to the control parameter. By applying the scheme provided by the embodiment, the accuracy of IABP inflation and deflation control can be improved.
Description
Technical Field
The application relates to the technical field of medical equipment, in particular to an IABP control method and device.
Background
IABP (Intra-aortic balloon counterpulsation) is an auxiliary support means for supporting cardiac function and improving hemodynamics. When the IABP is operated, the balloon in the IABP needs to be rapidly inflated and deflated at a specific moment in the cardiac cycle. How to accurately control the inflation and deflation of the IABP balloon is a need to be addressed.
Disclosure of Invention
The embodiment of the application aims to provide an IABP control method and device for accurately controlling inflation and deflation of an IABP balloon. The specific technical scheme is as follows:
in a first aspect, an embodiment of the present application provides an IABP control method, where the method includes:
acquiring an arterial blood pressure signal of a target object aimed at by an IABP, and determining an analysis signal corresponding to the arterial blood pressure signal and a blood pressure change signal representing the signal change characteristic of the arterial blood pressure signal, wherein the arterial blood pressure signal is: arterial blood pressure signals located prior to the current cardiac cycle and within an adjacent cardiac cycle;
performing global valley analysis and local valley analysis on the analysis signals, determining an intersection between a global valley set and a local valley set obtained by analysis, and determining signal points in the determined intersection as signal points representing active valve opening as valve opening points;
determining peak points in a first target signal segment between every two adjacent valve opening points in the analysis signal, and mapping the determined peak points to the blood pressure change signal to obtain mapping points of the blood pressure change signal;
determining a signal point representing aortic valve closure as a valve closure point based on the amplitude variation characteristic of each signal point in a second target signal segment between every two adjacent mapping points in the blood pressure variation signal;
determining the time of the valve opening point in the current cardiac cycle based on the determined time of the valve opening point, as the deflation time of the IABP, and determining the time of the valve closing point in the current cardiac cycle based on the determined time of the valve closing point, as the inflation time of the IABP, and controlling the balloon deflation/inflation of the IABP when the determined deflation time/inflation time is reached.
In one embodiment of the present application, determining, as the valve closing point, a signal point that characterizes aortic valve closing based on the amplitude variation characteristic of each signal point in the second target signal segment between every two adjacent mapping points in the blood pressure variation signal includes:
determining a signal point which meets a preset condition in a second target signal section between every two adjacent mapping points in the blood pressure change signal as a first signal point, wherein the preset condition is that the slope of a signal wave section where the signal point is positioned is positive and the amplitude is zero;
determining a peak point in each second target signal segment as a second signal point;
and determining a signal point representing aortic valve closure as a valve closure point based on the first signal point and the second signal point corresponding to each second target signal segment.
In an embodiment of the present application, determining, as the valve closing point, a signal point representing aortic valve closing based on the first signal point and the second signal point corresponding to each second target signal segment includes:
for each second target signal segment, a first signal point with a time sequence positioned before a corresponding second signal point in the corresponding first signal points is determined to be used as a valve closing point.
In one embodiment of the present application, the performing global valley analysis and local valley analysis on the resolved signal includes:
performing global index on the analytic signals to obtain a global valley set of the analytic signals;
and determining fourth signal points meeting preset conditions in signal points contained in the analysis signal, and determining a set formed by valley signal points in a third target signal section between every two adjacent fourth signal points in the analysis signal as a local valley set, wherein the preset conditions are that the slope of a signal wave band where the signal points are located is positive and the amplitude is zero.
In a second aspect, an embodiment of the present application provides an IABP control apparatus, where the apparatus includes:
the signal acquisition module is used for acquiring an arterial blood pressure signal of a target object aimed at by the IABP, determining an analysis signal corresponding to the arterial blood pressure signal and a blood pressure change signal representing the signal change characteristic of the arterial blood pressure signal, wherein the arterial blood pressure signal is: arterial blood pressure signals located prior to the current cardiac cycle and within an adjacent cardiac cycle;
the first signal point determining module is used for carrying out global valley analysis and local valley analysis on the analysis signals, determining an intersection between a global valley set and a local valley set obtained by analysis, and determining signal points in the determined intersection as signal points representing the opening of the active valve as valve opening points;
the signal point mapping module is used for determining peak points in a first target signal segment between every two adjacent valve opening points in the analysis signal, mapping the determined peak points to the blood pressure change signal and obtaining mapping points of the blood pressure change signal;
a second signal point determining module, configured to determine a signal point representing aortic valve closure as a valve closure point based on an amplitude variation characteristic of each signal point in a second target signal segment between every two adjacent mapping points in the blood pressure variation signal;
and the device control module is used for determining the time of the valve opening point in the current cardiac cycle based on the determined time of the valve opening point, determining the time of the valve closing point in the current cardiac cycle based on the determined time of the valve closing point, and controlling the balloon of the IABP to be deflated/inflated when reaching the determined deflating time/inflating time.
In an embodiment of the present application, the second signal point determining module includes:
a first signal point determining submodule, configured to determine a signal point that satisfies a preset condition in a second target signal segment between every two adjacent mapping points in the blood pressure change signal, as a first signal point, where the preset condition is that a slope of a signal band where the signal point is located is positive and an amplitude is zero;
the second signal point determining submodule is used for determining a peak point in each second target signal segment to serve as a second signal point;
and the third signal point determining submodule is used for determining a signal point representing aortic valve closure as a valve closing point based on the first signal point and the second signal point corresponding to each second target signal segment.
In an embodiment of the present application, the third signal point determining submodule is specifically configured to determine, for each second target signal segment, a first signal point, of the corresponding first signal points, whose timing sequence is located before the corresponding second signal point, as the valve closing point.
In one embodiment of the present application, the first signal point determining module is specifically configured to perform global indexing on the resolved signal to obtain a global valley set of the resolved signal; and determining fourth signal points meeting preset conditions in signal points contained in the analysis signal, and determining a set formed by valley signal points in a third target signal section between every two adjacent fourth signal points in the analysis signal as a local valley set, wherein the preset conditions are that the slope of a signal wave band where the signal points are located is positive and the amplitude is zero.
In a third aspect, an embodiment of the present application provides an electronic device, including a processor, a communication interface, a memory, and a communication bus, where the processor, the communication interface, and the memory complete communication with each other through the communication bus;
a memory for storing a computer program;
and a processor, configured to implement the method steps described in the first aspect when executing the program stored in the memory.
In a fourth aspect, an embodiment of the present application provides a computer readable storage medium, where a computer program is stored, where the computer program is executed by a processor to implement the method steps described in the first aspect.
From the above, it can be seen that, by applying the scheme provided by the embodiment of the present application, since the time of the valve opening point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, and the time of the valve closing point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, and since the time of the valve opening point and the time of the valve closing point of the adjacent cardiac cycle have stronger correlation, the determined time of the valve opening point of the current cardiac cycle can more accurately represent the actual valve opening time of the current cardiac cycle, and the determined time of the valve closing point of the current cardiac cycle can more accurately represent the actual valve closing time of the current cardiac cycle, so that the control of the inflation and deflation of the IABP based on the determined time of the valve opening point and the valve closing point of the current cardiac cycle can achieve improvement of the accuracy of the inflation and deflation control of the IABP.
On the one hand, the signal points in the intersection of the two valley sets are determined to be valve opening points, and on the other hand, the signal points in the intersection determined by integrating the two valley sets are determined to be valve opening points with high accuracy because the global valley sets are wide in range and the local valley sets are high in accuracy. On the other hand, since the amplitude change characteristic of the signal point in the blood pressure change signal is affected by valve closure, the valve closure point can be accurately determined based on the amplitude change characteristic of the signal point in the blood pressure change signal. In combination with the two aspects, the determined valve opening point can accurately represent the valve opening condition, and the valve closing point can accurately represent the valve closing condition.
Of course, not all of the above-described advantages need be achieved simultaneously in practicing any one of the products or methods of the present application.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following description will briefly introduce the drawings that are required to be used in the embodiments or the description of the prior art, and it is obvious that the drawings in the following description are only some embodiments of the present application, and other embodiments may also be obtained according to these drawings to those skilled in the art.
Fig. 1 is a schematic flow chart of an IABP control method provided in an embodiment of the present application;
FIG. 2a is a schematic diagram of an arterial blood pressure signal according to an embodiment of the present application;
FIG. 2b is a schematic diagram of a blood pressure variation signal according to an embodiment of the present disclosure;
FIG. 2c is a schematic diagram of an analytic signal according to an embodiment of the present disclosure;
fig. 3 is a schematic structural diagram of an IABP control device according to an embodiment of the present application;
fig. 4 is a schematic structural diagram of an electronic device according to an embodiment of the present application.
Detailed Description
The following description of the embodiments of the present application will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all, of the embodiments of the present application. Based on the embodiments herein, a person of ordinary skill in the art would be able to obtain all other embodiments based on the disclosure herein, which are within the scope of the disclosure herein.
The execution subject of embodiments of the present application may be a controller of the IABP for detecting relevant parameters of the IABP/patient and controlling the operation of the IABP.
Referring to fig. 1, fig. 1 is a schematic flow chart of an IABP control method according to an embodiment of the present application, where the method includes the following steps S101 to S105.
Step S101: and acquiring an arterial blood pressure signal of a target object aimed at by the IABP, and determining an analysis signal corresponding to the arterial blood pressure signal and a blood pressure change signal representing the signal change characteristic of the arterial blood pressure signal.
The arterial blood pressure signal is: arterial blood pressure signals located before and in the adjacent cardiac cycle.
The arterial blood pressure signal represents the pressure condition of the aorta of the target object, the analysis signal is used for representing the signal energy distribution condition of the arterial blood pressure signal, and the blood pressure change signal is used for representing the signal change characteristic of the arterial blood pressure signal.
Fig. 2a, 2b and 2c are schematic signal waveforms of an arterial blood pressure signal, a blood pressure change signal and an analysis signal, respectively.
The arterial blood pressure signal can be acquired by a pressure sensor integrated by the IABP, and the controller can read the arterial blood pressure signal from the memory.
The analysis signal and the blood pressure change signal may be converted from the arterial blood pressure signal in advance, the analysis signal and the blood pressure change signal are stored in the memory, and the controller may read the analysis signal and the blood pressure change signal corresponding to the arterial blood pressure signal from the memory. The controller may also perform signal conversion on the arterial blood pressure signal in real time after the arterial blood pressure signal is acquired.
In both the above two modes, the conversion of the arterial blood pressure signal is involved, specifically, the arterial blood pressure signal can be subjected to first-order differential operation to obtain a blood pressure change signal; and performing secondary Hilbert transformation on the blood pressure change signal to obtain an analysis signal corresponding to the arterial blood pressure signal.
Step S102: and carrying out global valley analysis and local valley analysis on the analysis signals, determining an intersection between the global valley set and the local valley set obtained by analysis, and determining signal points in the determined intersection as signal points representing the opening of the active valve as valve opening points.
The global valley analysis refers to a process of extracting a valley of an analysis signal from a signal overall angle analysis, and the local valley analysis refers to a process of extracting a valley of an analysis signal from a signal local angle analysis. The global valley analysis is from the global angle, the containing range is wider, the local valley analysis is from the local angle, the pertinence is higher, and the accuracy is higher.
The global valley sets contain the various valleys of the analytic signals obtained through the global valley analysis, and the local valley sets contain the various valleys of the analytic signals obtained through the local valley analysis.
The signal points in the intersection of the two valley sets are determined to be valve opening points, and the accuracy of the signal points in the intersection determined by integrating the two valley sets is high because the global valley sets are wide in range and the local valley sets are high in accuracy.
When the analysis signal is subjected to global valley analysis, the analysis signal can be subjected to global index to obtain the global valley of the analysis signal. The global index is to determine the amplitude of each signal point in the analysis signal, determine the valley value in the preset step length through the amplitude comparison in the preset step length, and determine the set formed by the determined valley values as a global valley value set.
When the analysis signal is subjected to local valley analysis, fourth signal points meeting preset conditions in signal points contained in the analysis signal can be determined, and a set formed by valley signal points in a third target signal segment between every two adjacent fourth signal points in the analysis signal is determined as a local valley set.
The preset condition is that the slope of the signal wave band where the signal point is located is positive and the amplitude is zero. When determining the fourth signal point, the analysis signal may be derived, a signal band with positive slope may be determined, and a signal point with zero amplitude in the signal band may be determined as the fourth signal point. The fourth signal point may also be referred to as a zero crossing.
And dividing the analysis signal by taking the fourth signal point as a division point. And determining signal points with the smallest amplitude in the third target signal section between every two adjacent fourth signal points, namely valley signal points, wherein a set formed by the valley signal points is a local valley set.
Because the analysis signals are subjected to global index, the obtained global valley value set can more fully cover the global valley value signal points of the analysis signals; meanwhile, the analysis signal is divided by utilizing the fourth signal points, and each third target signal segment is extracted by the targeted valley signal points, so that the obtained local valley set has higher pertinence and higher accuracy.
Step S103: and determining peak points in a first target signal segment between every two adjacent valve opening points in the analysis signals, and mapping the determined peak points to the blood pressure change signals to obtain mapping points of the blood pressure change signals.
Specifically, the amplitude of each signal point in the first target signal segment may be compared, and the peak point is determined based on the signal point with the largest amplitude. The amplitude values of the signal points in the preset range in the first target signal segment can be compared, the signal point with the largest amplitude value in each preset range is determined to be a peak point, in this case, a plurality of peak points are obtained, and the last peak point is mapped to the blood pressure change signal to obtain the mapping point of the blood pressure change signal.
Step S104: a signal point characterizing aortic valve closure is determined as a valve closure point based on the amplitude variation characteristics of each signal point within the second target signal segment between every two adjacent mapping points in the blood pressure variation signal.
The amplitude change characteristics include maximum amplitude, minimum amplitude, amplitude change rate, and the like.
When determining the valve closing point, in one implementation manner, signal points meeting preset conditions in second target signal segments between every two adjacent mapping points in the blood pressure change signal can be determined and used as first signal points, and peak points in each second target signal segment are determined and used as second signal points; and determining a signal point representing aortic valve closure as a valve closure point based on the first signal point and the second signal point corresponding to each second target signal segment.
The preset condition is that the slope of a signal wave band where the signal point is located is positive and the amplitude is zero.
Each mapping point divides the blood pressure change signal, the slope of each continuous wave band in the second target signal section between every two adjacent mapping points is determined, and the signal point with the amplitude of zero in the wave band with the positive slope is determined as the first signal point. Thus, a plurality of first signal points, which may also be referred to as zero crossings, exist in each second target signal segment.
And comparing the amplitude of the signal points in each second target signal segment, and determining the signal point with the largest amplitude as the second signal point.
In determining the valve closing point, in one embodiment, for each second target signal segment, a first signal point of the corresponding first signal points, whose timing is located before the corresponding second signal point, may be determined as the valve closing point. Since the first signal point with the time sequence before the second signal point is determined as the valve closing point, and through a lot of researches by the inventor, the valve closing point is located before the peak value of the blood pressure change signal and is related to the zero crossing point of the blood pressure change signal, the first signal point is determined as the valve closing point, so that the accurate positioning of the valve closing point is realized.
In another embodiment, the first signal point and the second signal point may be input into a pre-trained closing point prediction model, so as to obtain a signal point output by the closing point prediction model as a valve closing point. The closing point prediction model is a model for predicting a signal point of aortic valve closing using a neural network learning algorithm.
The valve closing point is determined through the first signal point and the second signal point, wherein the first signal point is a zero crossing point in the blood pressure change signal, the second signal point is a peak value in the blood pressure change signal, and the valve closing point is related to the zero crossing point and the peak value in the blood pressure change signal, so that the determined signal point is the valve closing point with higher accuracy.
Step S105: determining the time of the valve opening point in the current cardiac cycle based on the determined time of the valve opening point, as the deflation time of the IABP, and determining the time of the valve closing point in the current cardiac cycle based on the determined time of the valve closing point, as the inflation time of the IABP, and controlling the balloon deflation/inflation of the IABP when the determined deflation time/inflation time is reached.
The execution timing of the steps S101 to S105 may be executed before the current cardiac cycle or within a preset duration immediately after the start of the current cardiac cycle, so as to determine the inflation/deflation timing of the IABP in time.
The time of the valve opening point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, the time of the valve closing point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, and the time of the valve opening point and the time of the valve closing point of the adjacent cardiac cycle have strong correlation, so that the determined time of the valve opening point of the current cardiac cycle can accurately represent the actual valve opening time of the current cycle, and the determined time of the valve closing point of the current cardiac cycle can accurately represent the actual valve closing time of the current cycle.
When determining the time of the valve opening point and the time of the valve closing point in the current cardiac cycle, the time of extending the duration of the preset cardiac cycle after the determined time of the valve opening point can be calculated as the time of the valve opening point in the current cardiac cycle, and the time of extending the duration of the preset cardiac cycle after the determined time of the valve closing point can be calculated as the time of the valve closing point in the current cardiac cycle.
From the above, it can be seen that, by applying the scheme provided by the embodiment, since the time of the valve opening point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, and the time of the valve closing point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, and since the time of the valve opening point and the time of the valve closing point of the adjacent cardiac cycle have stronger correlation, the determined time of the valve opening point of the current cardiac cycle can more accurately represent the actual valve opening time of the current cycle, and the determined time of the valve closing point of the current cardiac cycle can more accurately represent the actual valve closing time of the current cycle, so that the control of the inflation and deflation of the IABP based on the determined time of the valve opening point and the valve closing point of the current cardiac cycle can achieve improvement of the accuracy of the inflation and deflation control of the IABP.
On the one hand, the signal points in the intersection of the two valley sets are determined to be valve opening points, and on the other hand, the signal points in the intersection determined by integrating the two valley sets are determined to be valve opening points with high accuracy because the global valley sets are wide in range and the local valley sets are high in accuracy. On the other hand, since the amplitude change characteristic of the signal point in the blood pressure change signal is affected by valve closure, the valve closure point can be accurately determined based on the amplitude change characteristic of the signal point in the blood pressure change signal. In combination with the two aspects, the determined valve opening point can accurately represent the valve opening condition, and the valve closing point can accurately represent the valve closing condition.
Corresponding to the IABP control method, the embodiment of the application also provides an IABP control device.
Referring to fig. 3, fig. 3 is a schematic structural diagram of an IABP control device according to an embodiment of the present application, where the device includes 301-305.
The signal acquisition module 301 is configured to acquire an arterial blood pressure signal of a target object to which the IABP is directed, and determine an analysis signal corresponding to the arterial blood pressure signal, and a blood pressure change signal that characterizes a signal change characteristic of the arterial blood pressure signal, where the arterial blood pressure signal is: arterial blood pressure signals located prior to the current cardiac cycle and within an adjacent cardiac cycle;
a first signal point determining module 302, configured to perform global valley analysis and local valley analysis on the analysis signal, determine an intersection between the global valley set and the local valley set obtained by the analysis, and determine a signal point in the determined intersection as a signal point representing active valve opening as a valve opening point;
a signal point mapping module 303, configured to determine a peak point in a first target signal segment between every two adjacent valve open points in the analysis signal, map the determined peak point to the blood pressure change signal, and obtain a mapped point of the blood pressure change signal;
a second signal point determining module 304, configured to determine a signal point representing aortic valve closure as a valve closure point based on an amplitude variation characteristic of each signal point in a second target signal segment between every two adjacent mapping points in the blood pressure variation signal;
the device control module 305 is configured to determine a time of the valve opening point in the current cardiac cycle based on the determined time of the valve opening point, as a deflation time of the IABP, and determine a time of the valve closing point in the current cardiac cycle based on the determined time of the valve closing point, as an inflation time of the IABP, and control balloon deflation/inflation of the IABP when the determined deflation time/inflation time is reached.
From the above, it can be seen that, by applying the scheme provided by the embodiment, since the time of the valve opening point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, and the time of the valve closing point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, and since the time of the valve opening point and the time of the valve closing point of the adjacent cardiac cycle have stronger correlation, the determined time of the valve opening point of the current cardiac cycle can more accurately represent the actual valve opening time of the current cycle, and the determined time of the valve closing point of the current cardiac cycle can more accurately represent the actual valve closing time of the current cycle, so that the control of the inflation and deflation of the IABP based on the determined time of the valve opening point and the valve closing point of the current cardiac cycle can achieve improvement of the accuracy of the inflation and deflation control of the IABP.
On the one hand, the signal points in the intersection of the two valley sets are determined to be valve opening points, and on the other hand, the signal points in the intersection determined by integrating the two valley sets are determined to be valve opening points with high accuracy because the global valley sets are wide in range and the local valley sets are high in accuracy. On the other hand, since the amplitude change characteristic of the signal point in the blood pressure change signal is affected by valve closure, the valve closure point can be accurately determined based on the amplitude change characteristic of the signal point in the blood pressure change signal. In combination with the two aspects, the determined valve opening point can accurately represent the valve opening condition, and the valve closing point can accurately represent the valve closing condition.
In one embodiment of the present application, the second signal point determining module 304 includes:
a first signal point determining submodule, configured to determine a signal point that satisfies a preset condition in a second target signal segment between every two adjacent mapping points in the blood pressure change signal, as a first signal point, where the preset condition is that a slope of a signal band where the signal point is located is positive and an amplitude is zero;
the second signal point determining submodule is used for determining a peak point in each second target signal segment to serve as a second signal point;
and the third signal point determining submodule is used for determining a signal point representing aortic valve closure as a valve closing point based on the first signal point and the second signal point corresponding to each second target signal segment.
The valve closing point is determined through the first signal point and the second signal point, wherein the first signal point is a zero crossing point in the blood pressure change signal, the second signal point is a peak value in the blood pressure change signal, and the valve closing point is related to the zero crossing point and the peak value in the blood pressure change signal, so that the determined signal point is the valve closing point with higher accuracy.
In an embodiment of the present application, the third signal point determining submodule is specifically configured to determine, for each second target signal segment, a first signal point, of the corresponding first signal points, whose timing sequence is located before the corresponding second signal point, as the valve closing point.
Since the first signal point with the time sequence before the second signal point is determined as the valve closing point, and through a lot of researches by the inventor, the valve closing point is located before the peak value of the blood pressure change signal and is related to the zero crossing point of the blood pressure change signal, the first signal point is determined as the valve closing point, so that the accurate positioning of the valve closing point is realized.
In one embodiment of the present application, the first signal point determining module 302 is specifically configured to perform global indexing on the resolved signal to obtain a global valley set of the resolved signal; and determining fourth signal points meeting preset conditions in signal points contained in the analysis signal, and determining a set formed by valley signal points in a third target signal section between every two adjacent fourth signal points in the analysis signal as a local valley set, wherein the preset conditions are that the slope of a signal wave band where the signal points are located is positive and the amplitude is zero.
Because the analysis signals are subjected to global index, the obtained global valley value set can more fully cover the global valley value signal points of the analysis signals; meanwhile, the analysis signal is divided by utilizing the fourth signal points, and each third target signal segment is extracted by the targeted valley signal points, so that the obtained local valley set has higher pertinence and higher accuracy.
Corresponding to the control method of the IABP, the embodiment of the application also provides electronic equipment.
Referring to fig. 4, fig. 4 is a schematic structural diagram of an electronic device according to an embodiment of the present application, including a processor 401, a communication interface 402, a memory 403, and a communication bus 404, where the processor 401, the communication interface 402, and the memory 403 complete communication with each other through the communication bus 404,
a memory 403 for storing a computer program;
the processor 401 is configured to implement the method for controlling the IABP provided in the embodiment of the present application when executing the program stored in the memory 403.
The communication bus mentioned above for the electronic devices may be a peripheral component interconnect standard (Peripheral Component Interconnect, PCI) bus or an extended industry standard architecture (Extended Industry Standard Architecture, EISA) bus, etc. The communication bus may be classified as an address bus, a data bus, a control bus, or the like. For ease of illustration, the figures are shown with only one bold line, but not with only one bus or one type of bus.
The communication interface is used for communication between the electronic device and other devices.
The Memory may include random access Memory (Random Access Memory, RAM) or may include Non-Volatile Memory (NVM), such as at least one disk Memory. Optionally, the memory may also be at least one memory device located remotely from the aforementioned processor.
The processor may be a general-purpose processor, including a central processing unit (Central Processing Unit, CPU), a network processor (Network Processor, NP), etc.; but also digital signal processors (Digital Signal Processor, DSP), application specific integrated circuits (Application Specific Integrated Circuit, ASIC), field programmable gate arrays (Field-Programmable Gate Array, FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components.
In yet another embodiment provided herein, a computer readable storage medium is further provided, where a computer program is stored, where the computer program is executed by a processor to implement a method for controlling an IABP provided in an embodiment of the present application.
In yet another embodiment provided herein, a computer program product containing instructions that, when executed on a computer, cause the computer to perform the method for controlling an IABP provided by the embodiments of the present application is also provided.
From the above, it can be seen that, by applying the scheme provided by the embodiment, since the time of the valve opening point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, and the time of the valve closing point of the current cardiac cycle is determined based on the time of the valve opening point of the previous adjacent cardiac cycle, and since the time of the valve opening point and the time of the valve closing point of the adjacent cardiac cycle have stronger correlation, the determined time of the valve opening point of the current cardiac cycle can more accurately represent the actual valve opening time of the current cycle, and the determined time of the valve closing point of the current cardiac cycle can more accurately represent the actual valve closing time of the current cycle, so that the control of the inflation and deflation of the IABP based on the determined time of the valve opening point and the valve closing point of the current cardiac cycle can achieve improvement of the accuracy of the inflation and deflation control of the IABP.
On the one hand, the signal points in the intersection of the two valley sets are determined to be valve opening points, and on the other hand, the signal points in the intersection determined by integrating the two valley sets are determined to be valve opening points with high accuracy because the global valley sets are wide in range and the local valley sets are high in accuracy. On the other hand, since the amplitude change characteristic of the signal point in the blood pressure change signal is affected by valve closure, the valve closure point can be accurately determined based on the amplitude change characteristic of the signal point in the blood pressure change signal. In combination with the two aspects, the determined valve opening point can accurately represent the valve opening condition, and the valve closing point can accurately represent the valve closing condition.
In the above embodiments, it may be implemented in whole or in part by software, hardware, firmware, or any combination thereof. When implemented in software, may be implemented in whole or in part in the form of a computer program product. The computer program product includes one or more computer instructions. When loaded and executed on a computer, produces a flow or function in accordance with embodiments of the present application, in whole or in part. The computer may be a general purpose computer, a special purpose computer, a computer network, or other programmable apparatus. The computer instructions may be stored in or transmitted from one computer-readable storage medium to another, for example, by wired (e.g., coaxial cable, optical fiber, digital Subscriber Line (DSL)), or wireless (e.g., infrared, wireless, microwave, etc.). The computer readable storage medium may be any available medium that can be accessed by a computer or a data storage device such as a server, data center, etc. that contains an integration of one or more available media. The usable medium may be a magnetic medium (e.g., floppy Disk, hard Disk, magnetic tape), an optical medium (e.g., DVD), or a semiconductor medium (e.g., solid State Disk (SSD)), etc.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
In this specification, each embodiment is described in a related manner, and identical and similar parts of each embodiment are all referred to each other, and each embodiment mainly describes differences from other embodiments. In particular, for apparatus, electronic devices, computer readable storage medium embodiments, since they are substantially similar to method embodiments, the description is relatively simple, and relevant references are made to the partial description of method embodiments.
The foregoing description is only of the preferred embodiments of the present application and is not intended to limit the scope of the present application. Any modifications, equivalent substitutions, improvements, etc. that are within the spirit and principles of the present application are intended to be included within the scope of the present application.
Claims (10)
1. An IABP control method, the method comprising:
acquiring an arterial blood pressure signal of a target object aimed at by an IABP, and determining an analysis signal corresponding to the arterial blood pressure signal and a blood pressure change signal representing the signal change characteristic of the arterial blood pressure signal, wherein the arterial blood pressure signal is: arterial blood pressure signals located prior to the current cardiac cycle and within an adjacent cardiac cycle;
performing global valley analysis and local valley analysis on the analysis signals, determining an intersection between a global valley set and a local valley set obtained by analysis, and determining signal points in the determined intersection as signal points representing active valve opening as valve opening points;
determining peak points in a first target signal segment between every two adjacent valve opening points in the analysis signal, and mapping the determined peak points to the blood pressure change signal to obtain mapping points of the blood pressure change signal;
determining a signal point representing aortic valve closure as a valve closure point based on the amplitude variation characteristic of each signal point in a second target signal segment between every two adjacent mapping points in the blood pressure variation signal;
determining the time of the valve opening point in the current cardiac cycle based on the determined time of the valve opening point, as the deflation time of the IABP, and determining the time of the valve closing point in the current cardiac cycle based on the determined time of the valve closing point, as the inflation time of the IABP, and controlling the balloon deflation/inflation of the IABP when the determined deflation time/inflation time is reached.
2. The method of claim 1, wherein the determining a signal point indicative of aortic valve closure as a valve closure point based on the amplitude variation characteristics of each signal point within the second target signal segment between every two adjacent mapping points in the blood pressure variation signal comprises:
determining a signal point which meets a preset condition in a second target signal section between every two adjacent mapping points in the blood pressure change signal as a first signal point, wherein the preset condition is that the slope of a signal wave section where the signal point is positioned is positive and the amplitude is zero;
determining a peak point in each second target signal segment as a second signal point;
and determining a signal point representing aortic valve closure as a valve closure point based on the first signal point and the second signal point corresponding to each second target signal segment.
3. The method of claim 2, wherein determining a signal point indicative of aortic valve closure as a valve closure point based on the first signal point and the second signal point corresponding to each second target signal segment comprises:
for each second target signal segment, a first signal point with a time sequence positioned before a corresponding second signal point in the corresponding first signal points is determined to be used as a valve closing point.
4. A method according to any of claims 1-3, wherein said performing global and local valley analysis on said resolved signal comprises:
performing global index on the analytic signals to obtain a global valley set of the analytic signals;
and determining fourth signal points meeting preset conditions in signal points contained in the analysis signal, and determining a set formed by valley signal points in a third target signal section between every two adjacent fourth signal points in the analysis signal as a local valley set, wherein the preset conditions are that the slope of a signal wave band where the signal points are located is positive and the amplitude is zero.
5. An IABP control device, the device comprising:
the signal acquisition module is used for acquiring an arterial blood pressure signal of a target object aimed at by the IABP, determining an analysis signal corresponding to the arterial blood pressure signal and a blood pressure change signal representing the signal change characteristic of the arterial blood pressure signal, wherein the arterial blood pressure signal is: arterial blood pressure signals located prior to the current cardiac cycle and within an adjacent cardiac cycle;
the first signal point determining module is used for carrying out global valley analysis and local valley analysis on the analysis signals, determining an intersection between a global valley set and a local valley set obtained by analysis, and determining signal points in the determined intersection as signal points representing the opening of the active valve as valve opening points;
the signal point mapping module is used for determining peak points in a first target signal segment between every two adjacent valve opening points in the analysis signal, mapping the determined peak points to the blood pressure change signal and obtaining mapping points of the blood pressure change signal;
a second signal point determining module, configured to determine a signal point representing aortic valve closure as a valve closure point based on an amplitude variation characteristic of each signal point in a second target signal segment between every two adjacent mapping points in the blood pressure variation signal;
and the device control module is used for determining the time of the valve opening point in the current cardiac cycle based on the determined time of the valve opening point, determining the time of the valve closing point in the current cardiac cycle based on the determined time of the valve closing point, and controlling the balloon of the IABP to be deflated/inflated when reaching the determined deflating time/inflating time.
6. The apparatus of claim 5, wherein the second signal point determination module comprises:
a first signal point determining submodule, configured to determine a signal point that satisfies a preset condition in a second target signal segment between every two adjacent mapping points in the blood pressure change signal, as a first signal point, where the preset condition is that a slope of a signal band where the signal point is located is positive and an amplitude is zero;
the second signal point determining submodule is used for determining a peak point in each second target signal segment to serve as a second signal point;
and the third signal point determining submodule is used for determining a signal point representing aortic valve closure as a valve closing point based on the first signal point and the second signal point corresponding to each second target signal segment.
7. The device of claim 6, wherein the third signal point determination submodule is configured to determine, for each second target signal segment, a first signal point of the corresponding first signal points whose timing is before the corresponding second signal point as a valve closing point.
8. The apparatus according to any one of claims 5-7, wherein the first signal point determining module is specifically configured to perform global indexing on the resolved signal to obtain a global valley set of the resolved signal; and determining fourth signal points meeting preset conditions in signal points contained in the analysis signal, and determining a set formed by valley signal points in a third target signal section between every two adjacent fourth signal points in the analysis signal as a local valley set, wherein the preset conditions are that the slope of a signal wave band where the signal points are located is positive and the amplitude is zero.
9. The electronic equipment is characterized by comprising a processor, a communication interface, a memory and a communication bus, wherein the processor, the communication interface and the memory are communicated with each other through the communication bus;
a memory for storing a computer program;
a processor for carrying out the method steps of any one of claims 1-4 when executing a program stored on a memory.
10. A computer-readable storage medium, characterized in that the computer-readable storage medium has stored therein a computer program which, when executed by a processor, implements the method steps of any of claims 1-4.
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