CN117229433A - Cyclic peroxide initiator containing hindered amine phlegmatizer and synthesis method and application thereof - Google Patents
Cyclic peroxide initiator containing hindered amine phlegmatizer and synthesis method and application thereof Download PDFInfo
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- -1 Cyclic peroxide Chemical class 0.000 title claims abstract description 53
- 150000001412 amines Chemical class 0.000 title claims abstract description 30
- 239000003999 initiator Substances 0.000 title claims abstract description 21
- 238000001308 synthesis method Methods 0.000 title claims abstract description 12
- 238000006243 chemical reaction Methods 0.000 claims abstract description 45
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 26
- 238000000034 method Methods 0.000 claims abstract description 26
- 238000003786 synthesis reaction Methods 0.000 claims abstract description 13
- 239000007864 aqueous solution Substances 0.000 claims abstract description 7
- 229940090898 Desensitizer Drugs 0.000 claims abstract description 5
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims description 16
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 12
- 239000004215 Carbon black (E152) Substances 0.000 claims description 10
- 239000003377 acid catalyst Substances 0.000 claims description 10
- 229930195733 hydrocarbon Natural products 0.000 claims description 10
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 9
- 230000015572 biosynthetic process Effects 0.000 claims description 9
- 150000002430 hydrocarbons Chemical class 0.000 claims description 9
- 239000011541 reaction mixture Substances 0.000 claims description 8
- 238000004321 preservation Methods 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 125000000864 peroxy group Chemical group O(O*)* 0.000 claims description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 4
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 claims description 4
- 150000001335 aliphatic alkanes Chemical class 0.000 claims description 4
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 claims description 4
- 150000003254 radicals Chemical class 0.000 claims description 4
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 claims description 4
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 claims description 3
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- 125000003118 aryl group Chemical group 0.000 claims description 3
- 229910017604 nitric acid Inorganic materials 0.000 claims description 3
- 125000001424 substituent group Chemical group 0.000 claims description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 2
- 239000004743 Polypropylene Substances 0.000 claims description 2
- 125000001931 aliphatic group Chemical group 0.000 claims description 2
- 238000004132 cross linking Methods 0.000 claims description 2
- XNLICIUVMPYHGG-UHFFFAOYSA-N pentan-2-one Chemical compound CCCC(C)=O XNLICIUVMPYHGG-UHFFFAOYSA-N 0.000 claims description 2
- 239000004033 plastic Substances 0.000 claims description 2
- 229920003023 plastic Polymers 0.000 claims description 2
- 229920001155 polypropylene Polymers 0.000 claims description 2
- 238000007348 radical reaction Methods 0.000 claims description 2
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 1
- 238000003889 chemical engineering Methods 0.000 abstract description 3
- 239000012847 fine chemical Substances 0.000 abstract description 3
- 230000003321 amplification Effects 0.000 abstract description 2
- 238000009776 industrial production Methods 0.000 abstract description 2
- 238000003199 nucleic acid amplification method Methods 0.000 abstract description 2
- 239000002253 acid Substances 0.000 abstract 1
- 238000006555 catalytic reaction Methods 0.000 abstract 1
- 238000005502 peroxidation Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 description 16
- 239000003921 oil Substances 0.000 description 12
- 150000002978 peroxides Chemical class 0.000 description 7
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 238000010907 mechanical stirring Methods 0.000 description 4
- XTAZYLNFDRKIHJ-UHFFFAOYSA-N n,n-dioctyloctan-1-amine Chemical compound CCCCCCCCN(CCCCCCCC)CCCCCCCC XTAZYLNFDRKIHJ-UHFFFAOYSA-N 0.000 description 4
- 238000010992 reflux Methods 0.000 description 4
- 230000002194 synthesizing effect Effects 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 description 3
- GTJOHISYCKPIMT-UHFFFAOYSA-N 2-methylundecane Chemical compound CCCCCCCCCC(C)C GTJOHISYCKPIMT-UHFFFAOYSA-N 0.000 description 3
- SGVYKUFIHHTIFL-UHFFFAOYSA-N Isobutylhexyl Natural products CCCCCCCC(C)C SGVYKUFIHHTIFL-UHFFFAOYSA-N 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- VKPSKYDESGTTFR-UHFFFAOYSA-N isododecane Natural products CC(C)(C)CC(C)CC(C)(C)C VKPSKYDESGTTFR-UHFFFAOYSA-N 0.000 description 3
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 241000751119 Mila <angiosperm> Species 0.000 description 1
- GPFIZJURHXINSQ-UHFFFAOYSA-N acetic acid;nitric acid Chemical compound CC(O)=O.O[N+]([O-])=O GPFIZJURHXINSQ-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000007810 chemical reaction solvent Substances 0.000 description 1
- 150000001923 cyclic compounds Chemical class 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000295 fuel oil Substances 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention belongs to the technical field of organic synthesis and fine chemical engineering, and particularly relates to a cyclic peroxide initiator containing a hindered amine phlegmatizer, and a synthesis method and application thereof. The initiator comprises cyclic peroxide and a hindered amine phlegmatizer, wherein the hindered amine phlegmatizer accounts for 10-80% of the weight of the cyclic peroxide. The preparation method of the initiator comprises the following steps: the ketone compound and hydrogen peroxide aqueous solution are used as raw materials, and the cyclic peroxide is obtained through peroxidation under the catalysis of acid, and a hindered amine desensitizer is added during or after the reaction. The process is safe and reliable, and can obtain the target product with high yield and high purity; the invention has mild reaction condition and simple process, and the product does not need to be purified; the process is environment-friendly, and is suitable for amplification and industrial production.
Description
Technical Field
The invention belongs to the technical field of organic synthesis and fine chemical engineering, and particularly relates to a cyclic peroxide initiator containing a hindered amine phlegmatizer, and a synthesis method and application thereof.
Background
The cyclic peroxide is a cyclic compound with a peroxy chain, namely-O-, and can be used as a free radical initiator and participate in oxidation reaction due to the existence of peroxy bonds and higher oxygen element content in a molecular structure, so that the cyclic peroxide can be used for various aspects of organic synthesis, new material processing and manufacturing, fuel oil performance improvement and the like, is an emerging important chemical product, and has wide application fields.
The compounds are typically of a structure type having 2 peroxide structural units from the smallest six-membered ring and 3 peroxide structural units from the nine-membered ring, and the larger ring, i.e. the compound having more peroxide structural units, is quite rare. The structural type with nine rings, i.e. 3 peroxide building blocks, has the following structural features:
r represents the same or different aliphatic alkyl or aromatic substituent groups.
The method reported in the literature for synthesizing the compound is single, the method for synthesizing the compound is reported for the first time in N.A. Milas in 1959, and related patent US3003000 is filed in 1961. The technical process developed by Milas is complex in operation, peroxide monomer is mainly obtained, the cyclic product is separated only in the form of impurities,
the yield is very low, and thus industrial mass production cannot be realized.
In 2004, WO2004/076405 by german dezasie corporation reports a process method for synthesizing acetic acid under the condition of using nitric acid as a solvent, such as isododecane, and the like, the reaction efficiency of the method is low, the components of the product are complex, the purification is required, the process is complex, the produced nitric acid-acetic acid mixture cannot be effectively utilized, and the process safety cannot be ensured.
WO2015/135865 filed by the company of akunobel in 2015 also examines the fact that various solvents such as isododecane are used as reaction solvents for synthesis, and the defects that the components of the product are complex and need to be separated and purified exist, so that the complex and the addition of the product are not facilitated, and the safety guarantee level of the process is low.
Disclosure of Invention
In order to solve the technical problems, the invention provides a cyclic peroxide initiator containing a hindered amine phlegmatizer, a synthesis method and application thereof, and the phlegmatizer is added into a reaction system or a reaction product to reduce the safety risk of a peroxide product and reduce the safety risk in production.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
in one aspect the present invention provides a cyclic peroxide initiator comprising a sterically hindered amine phlegmatiser, said initiator comprising a cyclic peroxide and a sterically hindered amine phlegmatiser, said sterically hindered amine phlegmatiser being present in an amount of from 10% to 80%, preferably from 30% to 60% by weight of the cyclic peroxide.
In the above technical scheme, further, the cyclic peroxide is a six-membered ring containing 2 peroxy groups in formula (i) or a nine-membered ring containing 3 peroxy groups in formula (ii):
r represents the same or different aliphatic alkyl or aromatic substituent groups.
In the above technical scheme, further, the hindered amine phlegmatizer is a hydrocarbon containing a hindered amine compound, and the structure of the hindered amine compound is shown in formula (iii) or formula (iv):
wherein R is 1 Represents various aliphatic alkyl groups of the same or different length, preferably C 5 ～C 10 An alkyl group;
the hydrocarbon comprises straight-chain alkane with a certain carbon chain length or isomer thereof, preferably C 8 ～C 18 Alkanes or isomers thereof, more preferably C 10 ～C 18 An alkane or isomer thereof;
in the hindered amine phlegmatizer, the content of the hindered amine compound is 0.5-20% of the weight of hydrocarbon, and is preferably 0.5-5%.
In the above technical scheme, further, the cyclic peroxide is 3,6, 9-triethyl-3, 6, 9-trimethyl-1, 4, 7-triperoxonane or 3,6, 9-bis (triethyl) -1,4, 7-triperoxonane.
In another aspect, the present invention provides a method for synthesizing the cyclic peroxide initiator containing the hindered amine phlegmatizer, comprising the steps of: adding a ketone compound into a reactor, adding a hydrocarbon desensitizer containing a hindered amine compound, adding an acid catalyst, controlling the temperature of a reaction system, then adding a hydrogen peroxide aqueous solution, controlling the temperature of the reaction system, standing the reaction mixture for layering after the heat preservation reaction is finished, and collecting an oil phase to obtain the cyclic peroxide containing the hindered amine sensitizer.
In a further aspect the present invention provides a process for the synthesis of a cyclic peroxide initiator comprising a sterically hindered amine phlegmatiser as described above, said process comprising the steps of: adding a ketone compound into a reactor, adding an acid catalyst, controlling the temperature of a reaction system, then adding a hydrogen peroxide aqueous solution, controlling the temperature of the reaction system, standing the reaction mixture for layering after the heat preservation reaction is finished, collecting an oil phase, and adding a hydrocarbon desensitizer containing a hindered amine compound into the oil phase to obtain the cyclic peroxide containing the hindered amine sensitizer.
In the above technical scheme, further, the ketone compound is one of acetone, butanone, pentanone and acetophenone; the acid catalyst is one or more of sulfuric acid, nitric acid, perchloric acid, acetic acid and p-toluenesulfonic acid; the mass concentration of the hydrogen peroxide aqueous solution is 10-70%.
In the technical scheme, the molar ratio of the ketone compound to the acid catalyst to the aqueous hydrogen peroxide solution is 1 (0.2-20): 1-10, preferably 1 (0.5-5): 1-5.
In the technical scheme, further, the reaction temperature is controlled to be in the range of-40 to 90 ℃ and preferably in the range of-10 to 50 ℃ when the acid catalyst is dropwise added; the reaction temperature is controlled within the range of-40 to 90 ℃, preferably-10 to 50 ℃ when the aqueous hydrogen peroxide solution is added dropwise.
The invention also provides an application of the cyclic peroxide initiator containing the hindered amine phlegmatizer in crosslinking reaction, free radical reaction or polypropylene plastic manufacturing.
Compared with the prior art, the invention has the beneficial effects that:
1. the addition of the phlegmatizer can effectively reduce the effective oxygen content in the reactant and the product, thereby achieving the aim of reducing the risk and ensuring and improving the safety of the technological process and the product;
2. the process is safe and reliable, and can obtain the target product with high yield and high purity;
3. the invention has mild reaction condition and simple process, and the product does not need to be purified;
4. the process is environment-friendly, is suitable for amplification and industrial production, and the byproducts are convenient to treat and recycle;
5. the cyclic peroxide molecular structure obtained by the synthesis process can be used as a free radical initiator or participate in oxidation reaction due to the existence of peroxide bonds and higher oxygen element content, and can be used in the fields of organic synthesis, fine chemical engineering and the like.
6. Compared with the like products sold in the market at present, the product obtained by the process is more suitable for adding and blending, is convenient to apply, can obtain accurate performance evaluation on the application effect of the annular peroxide, and has the advantages of obvious effect and convenient application.
Detailed Description
The treatment process according to the invention is further described below with reference to specific examples.
Unless otherwise indicated, all starting materials used in the examples of the present invention were commercially available.
Example 1
The synthesis of 3,6, 9-triethyl-3, 6, 9-trimethyl-1, 4, 7-triperoxonane is carried out according to the following synthetic route:
the feed ratio is shown in Table 1.
TABLE 1
The synthesis method comprises the following steps:
methyl ethyl ketone, trioctylamine and isododecane are added into a 500mL four-port reaction bottle, the reaction bottle is placed into a constant-temperature bath (bath temperature is 10 ℃), and mechanical stirring, a thermometer and a reflux condenser are arranged; adding sulfuric acid with the mass fraction of 75% through a dropping funnel, and controlling the reaction temperature to be lower than 30 ℃; hydrogen peroxide with the concentration of 50% is added dropwise through a dropping funnel, the temperature of the reaction system is controlled to be lower than 40 ℃ due to the heating phenomenon; after dripping, carrying out heat preservation reaction for 5hrs at 40 ℃; finishing the reaction, transferring the reaction mixture into a separating funnel, standing for 30min and layering; obtaining an oil phase and a water phase;
wherein the oil phase is 123g of product, yield: 74% (calculated as 3,6, 9-triethyl-3, 6, 9-trimethyl-1, 4, 7-triperoxonane).
Example 2
The synthesis of 3,6, 9-triethyl-3, 6, 9-trimethyl-1, 4, 7-triperoxonane is carried out according to the following synthetic route:
the feed ratio is shown in Table 2.
TABLE 2
The synthesis method comprises the following steps: methyl ethyl ketone, trioctylamine and isohexadecane are added into a 500mL four-port reaction bottle, the reaction bottle is placed into a constant-temperature bath (bath temperature is 10 ℃), and mechanical stirring, a thermometer and a reflux condenser are arranged; adding sulfuric acid with the mass fraction of 75% through a dropping funnel, and controlling the reaction temperature to be lower than 20 ℃; hydrogen peroxide with the concentration of 50% is added dropwise through a dropping funnel, the temperature of the reaction system is controlled to be lower than 20 ℃ due to the heating phenomenon; after dripping, the mixture is reacted for 5hrs at 20 ℃; finishing the reaction, transferring the reaction mixture into a separating funnel, standing for 30min and layering; obtaining an oil phase and a water phase;
wherein the oil phase is 120g of product, yield: 71% (calculated as 3,6, 9-triethyl-3, 6, 9-trimethyl-1, 4, 7-triperoxonane).
Example 3
The synthesis of 3,6, 9-triethyl-3, 6, 9-trimethyl-1, 4, 7-triperoxonane is carried out according to the following synthetic route:
the feed ratio is shown in Table 3.
TABLE 3 Table 3
The synthesis method comprises the following steps: methyl ethyl ketone, trioctylamine and isohexadecane are added into a 500mL four-port reaction bottle, the reaction bottle is placed into a constant-temperature bath (bath temperature is 10 ℃), and mechanical stirring, a thermometer and a reflux condenser are arranged; adding sulfuric acid with the mass fraction of 75% through a dropping funnel, and controlling the reaction temperature to be lower than 40 ℃; hydrogen peroxide with the concentration of 50% is added dropwise through a dropping funnel, the temperature of the reaction system is controlled to be lower than 40 ℃ due to the heating phenomenon; after dripping, carrying out heat preservation reaction for 5hrs at 40 ℃; finishing the reaction, transferring the reaction mixture into a separating funnel, standing for 30min and layering; obtaining an oil phase and a water phase;
wherein the oil phase is 125g of product, yield: 75% (calculated as 3,6, 9-triethyl-3, 6, 9-trimethyl-1, 4, 7-triperoxonane).
Example 4
The synthesis of 3,6, 9-triethyl-3, 6, 9-trimethyl-1, 4, 7-triperoxonane is carried out according to the following synthetic route:
the feed ratio is shown in Table 4.
TABLE 4 Table 4
The synthesis method comprises the following steps: methyl ethyl ketone is added into a 500mL four-port reaction bottle, the reaction bottle is placed into a constant-temperature bath (bath temperature is 10 ℃), and mechanical stirring, a thermometer and a reflux condenser are arranged; adding sulfuric acid with the mass fraction of 75% through a dropping funnel, and controlling the reaction temperature to be lower than 40 ℃; hydrogen peroxide with the concentration of 50% is added dropwise through a dropping funnel, the temperature of the reaction system is controlled to be lower than 40 ℃ due to the heating phenomenon; after dripping, the mixture is reacted for 3hrs at 40 ℃; finishing the reaction, transferring the reaction mixture into a separating funnel, standing for 30min and layering; obtaining an oil phase and a water phase; adding trioctylamine and isohexadecane into the oil phase, and stirring uniformly.
Wherein the oil phase is 125g of product, yield: 75% (calculated as 3,6, 9-triethyl-3, 6, 9-trimethyl-1, 4, 7-triperoxonane).
Many possible variations and modifications of the disclosed technology can be made by anyone skilled in the art without departing from the scope of the technology, or the technology can be modified to be equivalent. Therefore, any simple modification, equivalent variation and modification of the above embodiments according to the technical substance of the present invention shall still fall within the scope of the technical solution of the present invention.
Claims (9)
1. A cyclic peroxide initiator comprising a sterically hindered amine phlegmatiser, characterized in that: the initiator comprises cyclic peroxide and a hindered amine phlegmatizer, wherein the hindered amine phlegmatizer accounts for 10-80% of the weight of the cyclic peroxide.
2. The cyclic peroxide initiator containing a sterically hindered amine phlegmatiser according to claim 1, wherein: the cyclic peroxide is a six-membered ring containing 2 peroxy groups in formula (I) or a nine-membered ring containing 3 peroxy groups in formula (II):
r represents the same or different aliphatic alkyl or aromatic substituent groups.
3. The cyclic peroxide initiator containing a sterically hindered amine phlegmatiser according to claim 1, wherein: the hindered amine phlegmatizer is hydrocarbon containing a hindered amine compound, and the structure of the hindered amine compound is shown as a formula (III) or a formula (IV):
wherein R is 1 Represents various aliphatic alkyl groups of the same or different length;
the hydrocarbon comprises a linear alkane having a carbon chain length or an isomer thereof;
in the hindered amine phlegmatizer, the content of the hindered amine compound is 0.5-20% of the weight of hydrocarbon.
4. A process for the synthesis of a cyclic peroxide initiator containing a sterically hindered amine phlegmatiser as claimed in any one of claims 1 to 3, characterised in that:
the method comprises the following steps: adding a ketone compound into a reactor, adding a hydrocarbon desensitizer containing a hindered amine compound, adding an acid catalyst, controlling the temperature of a reaction system, then adding a hydrogen peroxide aqueous solution, controlling the temperature of the reaction system, standing the reaction mixture for layering after the heat preservation reaction is finished, and collecting an oil phase to obtain the cyclic peroxide containing the hindered amine sensitizer.
5. A process for the synthesis of a cyclic peroxide initiator containing a sterically hindered amine phlegmatiser as claimed in any one of claims 1 to 3, characterised in that: the method comprises the following steps: adding a ketone compound into a reactor, adding an acid catalyst, controlling the temperature of a reaction system, then adding a hydrogen peroxide aqueous solution, controlling the temperature of the reaction system, standing the reaction mixture for layering after the heat preservation reaction is finished, collecting an oil phase, and adding a hydrocarbon desensitizer containing a hindered amine compound into the oil phase to obtain the cyclic peroxide containing the hindered amine sensitizer.
6. The synthesis method according to claim 4 or 5, wherein: the ketone compound is one of acetone, butanone, pentanone and acetophenone;
the acid catalyst is one or more of sulfuric acid, nitric acid, perchloric acid, acetic acid and p-toluenesulfonic acid;
the mass concentration of the hydrogen peroxide aqueous solution is 10-70%.
7. The synthesis method according to claim 4 or 5, wherein: the molar ratio of the ketone compound to the acid catalyst to the aqueous hydrogen peroxide solution is 1 (0.2-20): 1-10.
8. The synthesis method according to claim 4 or 5, wherein: the reaction temperature range is controlled to be-40-90 ℃ when the acid catalyst is dripped; the reaction temperature is controlled to be-40-90 ℃ when the aqueous hydrogen peroxide solution is dripped.
9. Use of a cyclic peroxide initiator containing a sterically hindered amine phlegmatiser as claimed in any of claims 1 to 3 in a cross-linking reaction, a free radical reaction or in the manufacture of polypropylene plastics.
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