CN117214448A - Method and apparatus for preventing misaddition of sample - Google Patents

Method and apparatus for preventing misaddition of sample Download PDF

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Publication number
CN117214448A
CN117214448A CN202311187001.7A CN202311187001A CN117214448A CN 117214448 A CN117214448 A CN 117214448A CN 202311187001 A CN202311187001 A CN 202311187001A CN 117214448 A CN117214448 A CN 117214448A
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China
Prior art keywords
sample
target
pipetting
hole
component
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CN202311187001.7A
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Chinese (zh)
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冯文聪
袁丽媛
梁凤琼
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Dongguan Integrated Traditional Chinese And Western Medicine Hospital
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Dongguan Integrated Traditional Chinese And Western Medicine Hospital
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Priority to CN202311187001.7A priority Critical patent/CN117214448A/en
Publication of CN117214448A publication Critical patent/CN117214448A/en
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The application relates to the field of sample detection, and discloses a method and a device for preventing a sample from being added by mistake, wherein the method comprises the following steps: when a target sample is added to a target sample hole of a sample plate, a transmitting component on a liquid dispenser sends out a liquid-transferring signal; a target receiving component corresponding to the target sample hole receives the pipetting signal; responding to the received pipetting signals, and sending out target indication information by a target indication assembly corresponding to the target sample hole when the sample is added subsequently; the target indication information comprises visible rays; wherein, the sample board is transparent structure, is equipped with a plurality of sample holes on the sample board, and every sample hole on the sample board corresponds a receiving module and an instruction subassembly, and receiving module and instruction subassembly all locate the bottom of sample board and locate between the adjacent sample hole. The application simplifies the structure of the structure for preventing the sample from being added by mistake and improves the convenience of the structure for preventing the sample from being added by mistake.

Description

Method and apparatus for preventing misaddition of sample
Technical Field
The application relates to the technical field of sample detection, in particular to a method and a device for preventing a sample from being added by mistake.
Background
In various medical test items in hospitals, whether it is an assay for blood or body fluid, or an assay for patient excreta, it is generally necessary to perform an assay on a plurality of samples simultaneously in order to ensure stability of an assay result and perform a rapid assay, and thus, it is common to perform a concentrated assay by adding samples to a sample plate during an assay. For example, when performing certain biochemical tests using an enzyme-labeled instrument, a sample plate may be used to hold the sample and reagents to be assayed. For another example, in actual use, 96 samples may be assayed simultaneously using a sample plate of 96 sample wells. During use of the sample plate, it is generally necessary to sequentially add a plurality of reagents to the sample wells of the sample plate using a pipette. Because the number of sample holes and samples to be assayed on the sample plate is large, and the samples added in the sample holes are usually colorless liquid, an assaying person easily forgets which sample hole the sample is added in the last operation in the process of adding the sample to the sample plate by using a liquid shifter, and the repeated addition of the sample to the sample holes or the omission of the sample addition to a certain sample hole is easily caused.
Patent CN213475930U (application number: 202021666534.5) provides a 96-well plate mechanical error-proofing indicator, which comprises a base plate, a 96-well plate, a protruding strip and identification buttons, wherein a row type digital indicator is transversely arranged on the left and right direction of the end surface of the 96-well plate, a row type letter indicator is arranged on the up and down longitudinal direction of the end surface of the 96-well plate, a plurality of identification buttons are arranged on the base plate and transversely distributed in parallel, the plurality of identification buttons correspond to the row type digital indicator, and the identification buttons comprise an outer shell and an inner shell. The indicating button in the patent CN213475930U adopts a mechanical adjustment mode, so that omission or repeated sample adding in the operation process can be avoided, and adverse effects of light and electromagnetism on some cells and samples can be avoided. However, the indication button in CN213475930U requires manual rotation of the casing when switching between the first and second states during operation, so that the stopper moves along the vertical slot and cooperates with the first or second lateral limit slot, which results in a complex structure for preventing erroneous addition of the sample, and increases the workload when adding the sample into the sample hole, resulting in complicated operation when adding the sample into the sample hole, and is not suitable for use in actual sample assay work.
Disclosure of Invention
The application aims to provide a method and a device for preventing a sample from being added by mistake, which solve the technical problems of complex structure and complicated operation of preventing the sample from being added by mistake, and achieve the technical effects of simplifying the structure for preventing the sample from being added by mistake and being convenient to operate.
The embodiment of the application provides a method and a device for preventing a sample from being added by mistake, wherein the method comprises the following steps: when a target sample is added to a target sample hole of a sample plate, a transmitting component on a liquid dispenser sends out a liquid-transferring signal; a target receiving component corresponding to the target sample hole receives the pipetting signal; responding to the received pipetting signals, and sending out target indication information by a target indication assembly corresponding to the target sample hole when the sample is added subsequently; the target indication information comprises visible rays; wherein, the sample board is transparent structure, is equipped with a plurality of sample holes on the sample board, and every sample hole on the sample board corresponds a receiving module and an instruction subassembly, and receiving module and instruction subassembly all locate the bottom of sample board and locate between the adjacent sample hole.
In one possible implementation, the method further includes: placing a sample plate in a positioning flange on a base; the receiving assembly and the indicating assembly are arranged on the base, and each receiving assembly and each indicating assembly are respectively and electrically connected with the indicating control assembly; when a sample is added to a target sample hole of a sample plate, a transmitting assembly on the liquid dispenser is triggered to send out a liquid-transferring signal when the liquid dispenser extrudes the sample; the indication control component stores the target number of the target sample hole and controls the target indication component to send out target indication information according to the target number of the target sample hole.
In another possible implementation, the pipette comprises a housing, an extrusion rod, a photoelectric switch, a power supply assembly and a signal control assembly, wherein the extrusion rod is slidably connected in the housing, the power supply assembly and the signal control assembly are fixedly connected in the housing, and the emission assembly is connected to the outer side wall of a liquid tube ejection rod of the pipette; a limiting flange is arranged in the shell, and the photoelectric switch is fixedly connected to the limiting flange; the extruding rod is provided with a baffle, the baffle can trigger the photoelectric switch when the extruding rod extrudes a sample, and the transmitting assembly, the photoelectric switch and the power supply assembly are respectively and electrically connected with the signal control assembly.
In another possible implementation manner, the transmitting assembly comprises a connecting seat and a transmitting head, the connecting seat is fixedly connected to the liquid pipe ejecting rod, the transmitting head is rotationally connected to the connecting seat, a wire plug terminal electrically connected with the signal control assembly is arranged on the shell, and the transmitting head is electrically connected with the wire plug terminal through the wire plug terminal.
In another possible implementation manner, the signal control component is provided with a plurality of kinds of buttons, the kinds of buttons protrude from the housing, different kinds of buttons are used for controlling the emission component to emit pipetting signals corresponding to different sample kinds, and the method further includes: when a target sample of a target sample type is added to a target sample hole of the sample plate, a target sample button corresponding to the target sample type is pressed, and a target pipetting signal corresponding to the target sample type is sent out by an emitter head of the emitter assembly; a target receiving component corresponding to the target sample hole receives a target pipetting signal; responding to the received target pipetting signal, and sending out target indication information corresponding to the target sample type by the indication component when the sample is added subsequently; the target indication information corresponding to different target sample types corresponds to visible rays of different colors.
In another possible implementation, a pipetting sensor electrically connected to the indication control assembly is provided on the base, and the method further includes: when the pipetting detecting sensor is not shielded, the indication components corresponding to all the sample holes do not send out target indication information; when the pipetting detecting sensor is shielded, the target indicating assembly corresponding to the target sample hole to which the sample is added sends out target indicating information.
In another possible implementation, the method further includes: storing different sample areas corresponding to sample holes on a sample plate in an indication control assembly, wherein receiving assemblies of the sample holes in the different sample areas correspond to different target pipetting signals, and indication assemblies of the sample holes in the different sample areas correspond to different target indication information; different target indication information corresponds to different colors of visible rays; when a target sample is added to a target sample hole of a target sample area of the sample plate, a target sample button corresponding to a target pipetting signal of the target sample area is pressed, and a target pipetting signal corresponding to the target sample button is sent out by an emitter of the emitter component; a target receiving component corresponding to a target sample hole of the target sample area receives a target pipetting signal; when the sample is added later, the target indication component corresponding to the target sample hole of the target sample area sends out target indication information corresponding to the target sample area.
In another possible implementation, the method further includes: storing the target addition pattern within the indication control component; the target adding mode comprises a continuous adding mode and an interval adding mode, wherein the continuous adding mode is used for continuously adding samples to all sample holes in the sample area, and the interval adding mode is used for adding samples to every two sample holes Kong Liuchu in the sample area; when the target sample is added into the target sample hole, the indication control component controls the indication component to send out target indication information to indicate the target sample hole according to the target addition mode.
In another possible implementation, the method further includes: when the target sample area corresponding to the target sample hole stored by the indicating control component is matched with the target sample area corresponding to the target pipetting information received by the target sample hole, or when the sample type information corresponding to the target sample hole stored by the indicating control component is matched with the sample type information corresponding to the target pipetting information received by the target sample hole, the indicating component corresponding to the target sample hole sends out visible light rays for sample matching, or the indicating control component sends out sound information for sample matching; when the target sample area corresponding to the target sample hole stored by the indicating control component is not matched with the target sample area corresponding to the target pipetting information received by the target sample hole, or when the sample type information corresponding to the target sample hole stored by the indicating control component is not matched with the sample type information corresponding to the target pipetting information received by the target sample hole, the indicating component corresponding to the target sample hole sends out visible light rays of sample mismatch, or the indicating control component sends out sound information of sample mismatch.
In another possible implementation, the method further includes: when the target sample area corresponding to the target sample hole stored by the indication control component is not matched with the target sample area of the target pipetting information received by the target sample hole, or when the sample type information corresponding to the target sample hole stored by the indication control component is not matched with the sample type information of the target pipetting information received by the target sample hole, the indication control component stores the number corresponding to the target sample hole, and when the sample is added subsequently, the indication component corresponding to the target sample hole sends out mistakenly-added sample indication information which comprises visible light rays with different colors from the target indication information.
In another possible implementation, the method further includes: storing sample plate information of the sample plate and sample addition information of all sample holes on the sample plate, and uploading the sample plate information and the sample addition information to a server; when the first sample Kong Wu is added, the sample detection results in all the sample wells around the first sample well on the sample plate are discarded, and the pipetting signals of the first sample well on the sample plate and the pipetting signals of all the sample wells around the first sample well on the sample plate are stored.
The application also provides a device for preventing the false addition of the sample, which comprises a sample plate, a liquid shifter and a base, wherein the base is provided with a positioning flange for positioning the sample plate, the liquid shifter is provided with a transmitting component for transmitting a liquid shifting signal, the base is provided with a receiving component and an indicating component, the receiving component is used for receiving the liquid shifting signal, and the indicating component is used for transmitting indicating information according to the liquid shifting signal, and the indicating information corresponds to the liquid shifting signal.
Compared with the prior art, the embodiment of the application has the beneficial effects that:
the embodiment of the application provides a method for preventing a sample from being added by mistake, which comprises the following steps: when a target sample is added to a target sample hole of the sample plate, a transmitting component on the liquid dispenser sends out a liquid-transferring signal, and the liquid-transferring signal can indicate that the liquid dispenser is adding the target sample; a target receiving component corresponding to the target sample hole receives the pipetting signal; responding to the received pipetting signals, and sending out target indication information by a target indication component corresponding to a target sample hole when the sample is added later, wherein the target indication information is used for indicating the result of adding the target sample and preventing the sample from being added into the added sample hole by mistake when the sample is added later; the target indication information comprises visible rays; wherein, the sample board is transparent structure, be equipped with a plurality of sample holes on the sample board, every sample hole on the sample board corresponds a receiving module and an instruction subassembly, receiving module and instruction subassembly all locate the bottom of sample board and locate between the adjacent sample hole, through receiving module direct reception the information of the sample of interpolation, and instruct the interpolation result of sample through target indication information, can instruct the result of interpolation sample accurately through target indication information, compare and prevent the mistake through mechanical structure and add the sample, simplified the structure of preventing the mistake and add the sample, the convenience when having improved the prevention mistake and adding the sample.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the embodiments or the description of the prior art will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a flow chart of a method for preventing false addition of a sample according to an embodiment of the present application;
FIG. 2 is a schematic diagram showing a front view of a method for preventing a sample from being added by mistake in the use of the method according to the embodiment of the present application;
FIG. 3 is a schematic view of a partial structure at A of the method for preventing erroneous addition of a sample in FIG. 2;
FIG. 4 is a schematic diagram showing an exploded front view of a method for preventing erroneous application of a sample according to an embodiment of the present application;
FIG. 5 is a schematic view showing a partial cross-sectional structure of a pipette according to an embodiment of the present application;
FIG. 6 is a schematic view showing a part of a construction of a portion B of the pipette of FIG. 5;
FIG. 7 is a schematic view showing a part of a structure of a pipette of FIG. 1 at C;
FIG. 8 is a schematic view showing a part of a structure of a pipette of FIG. 1 at D;
FIG. 9 is a schematic diagram of a control structure of a pipette according to an embodiment of the present application;
FIG. 10 is a flow chart of another method for preventing false addition of a sample according to an embodiment of the present application;
FIG. 11 is a schematic top view of a sample plate according to an embodiment of the present application;
FIG. 12 is a schematic view of a portion of the sample plate of FIG. 11 at E;
FIG. 13 is a schematic top view of a sample plate according to an embodiment of the present application;
in the figure, 1, a sample plate; 11. a sample well; 2. a pipette; 21. a transmitting assembly; 211. a connecting seat; 212. a transmitting head; 22. a housing; 221. a limiting flange; 23. extruding a rod; 231. a baffle; 24. an optoelectronic switch; 25. a power supply assembly; 26. a signal control assembly; 261. a category button; 27. a liquid tube ejecting rod; 3. a base; 31. a receiving assembly; 32. an indication assembly; 33. an indication control assembly; 34. positioning a flange; 35. pipetting detecting sensor.
Detailed Description
In order to make the technical problems, technical schemes and beneficial effects to be solved more clear, the application is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the application.
It will be understood that when an element or structure is referred to as being "mounted" or "disposed" on another element or structure, it can be directly on the other element or structure or be indirectly on the other element or structure. When an element or structure is referred to as being "connected to" another element or structure, it can be directly connected to the other element or structure or be indirectly connected to the other element or structure.
It is to be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are merely for convenience in describing and simplifying the description based on the orientation or positional relationship shown in the drawings, and do not indicate or imply that the apparatus or one component or structure referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the application.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present application, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
Patent CN213475930U (application number: 202021666534.5) provides a 96-well plate mechanical error-proofing indicator, which comprises a base plate, a 96-well plate, a protruding strip and identification buttons, wherein a row type digital indicator is transversely arranged on the left and right direction of the end surface of the 96-well plate, a row type letter indicator is arranged on the up and down longitudinal direction of the end surface of the 96-well plate, a plurality of identification buttons are arranged on the base plate and transversely distributed in parallel, the plurality of identification buttons correspond to the row type digital indicator, and the identification buttons comprise an outer shell and an inner shell. The indicating button in the patent CN213475930U adopts a mechanical adjustment mode, so that omission or repeated sample adding in the operation process can be avoided, and adverse effects of light and electromagnetism on some cells and samples can be avoided. However, the indication button in CN213475930U requires manual rotation of the casing when switching between the first and second states during operation, so that the stopper moves along the vertical slot and cooperates with the first or second lateral limit slot, which results in a complex structure for preventing erroneous addition of the sample, and increases the workload when adding the sample into the sample hole, resulting in complicated operation when adding the sample into the sample hole, and is not suitable for use in actual sample assay work.
For the above reasons, an embodiment of the present application provides a method for preventing a sample from being added by mistake, the method including: when a target sample is added to a target sample hole of the sample plate, a transmitting component on the liquid dispenser sends out a liquid-transferring signal, and the liquid-transferring signal can indicate that the liquid dispenser is adding the target sample; a target receiving component corresponding to the target sample hole receives the pipetting signal; responding to the received pipetting signals, and sending out target indication information by a target indication component corresponding to a target sample hole when the sample is added later, wherein the target indication information is used for indicating the result of adding the target sample and preventing the sample from being added into the added sample hole by mistake when the sample is added later; the target indication information comprises visible rays; wherein, the sample board is transparent structure, be equipped with a plurality of sample holes on the sample board, every sample hole on the sample board corresponds a receiving module and an instruction subassembly, receiving module and instruction subassembly all locate the bottom of sample board and locate between the adjacent sample hole, through receiving module direct reception the information of the sample of interpolation, and instruct the interpolation result of sample through target indication information, can instruct the result of interpolation sample accurately through target indication information, compare and prevent the mistake through mechanical structure and add the sample, simplified the structure of preventing the mistake and add the sample, the convenience when having improved the prevention mistake and adding the sample.
In some scenes, the method for preventing the false addition of the sample can be applied to the process of adding the sample in the blood test, the urine test and other tests in a hospital, so that the structure of the product for preventing the false addition of the sample in the conventional hospital test is simplified, and the simplicity of the operation during the false addition of the sample in the hospital test is improved.
In other cases, the method for preventing the false addition of the sample can be applied to the addition of experimental samples in biochemical experiments, so that the structure of the product for preventing the false addition of the sample in the existing experiments is simplified, and the simplicity of the operation during the false addition of the sample in the experiments is improved.
The following describes a method and apparatus for preventing erroneous addition of a sample according to embodiments of the present application with reference to specific examples.
Fig. 1 is a schematic flow chart of a method for preventing a sample from being added by mistake in the embodiment of the present application, and as shown in fig. 1, the method for preventing a sample from being added by mistake provided in the embodiment of the present application includes S110 to S130, and S110 to S130 are specifically described below.
S110, when a target sample is added to the target sample hole of the sample plate 1, a pipetting signal is sent out by the emitting component 21 on the pipettor 2.
Fig. 2 is a schematic front view of a method for preventing a sample from being added by mistake in the embodiment of the present application, and as shown in fig. 2, a sample plate 1 is of a transparent structure, and a plurality of sample holes 11 are provided on the sample plate 1, and the plurality of sample holes 11 are used for respectively holding samples for sample assay and detection.
In use, a sample, typically a liquid, may be added to the sample plate 1 via the pipette 2.
In use, when a target sample is added to a target sample hole of the sample plate 1 through the pipette 2, the emission component 21 on the pipette 2 sends out a pipetting signal, and the subsequent pipetting signal sent out by the emission component 21 can prevent the erroneous addition of the sample.
S120, receiving the pipetting signals by the target receiving assembly corresponding to the target sample hole.
Fig. 3 is a schematic partial structure at a point a of the method for preventing the erroneous addition of a sample in fig. 2, and structurally, as shown in fig. 2 and 3, each sample hole 11 on the sample plate 1 corresponds to one receiving component 31, so that a pipetting signal can be received by the corresponding receiving component 31 of each sample hole 11, and further, the erroneous addition of a sample can be prevented by receiving the pipetting signal.
When the sample receiving device is used, after the target receiving component corresponding to the target sample hole receives the pipetting signals, the samples can be prevented from being added by mistake according to the pipetting signals received by the target receiving component corresponding to each target sample hole, and further, the samples can be prevented from being added by mistake accurately for each sample hole 11.
When the device is used, only the target receiving components corresponding to the target sample holes can be controlled to be in an electrified state, the receiving components 31 except the target receiving components corresponding to the target sample holes are kept in a power-off state, further, only the target receiving components corresponding to the target sample holes can be controlled to receive pipetting signals, all the other sample holes 11 do not receive pipetting signals, at the moment, only one target sample hole exists, and a user can add a target sample into the target sample hole. Since the transmitting component 21 is fixedly connected to the liquid dispenser 2, when the liquid dispenser 2 is used, the liquid dispenser 2 is only required to be held in a fixed posture, then the liquid outlet of the liquid dispenser 2 is aligned to the target sample hole, and the transmitting component 21 of the liquid dispenser 2 is aligned to the target receiving component, so that the sample in the liquid dispenser 2 can be smoothly added into the target sample hole, and the liquid dispenser signal is received by the target receiving component corresponding to the target sample hole.
When the device is used, only the target receiving components corresponding to the target sample holes without the added sample can be controlled to be in an electrified state, the receiving components 31 except the target receiving components corresponding to the sample holes with the added sample are kept in a power-off state, further, only the target receiving components corresponding to the target sample holes without the added sample can be controlled to receive pipetting signals, the rest sample holes 11 do not receive pipetting signals, at the moment, one or more target sample holes are arranged, and a user can selectively add the target sample in one or more target sample holes. Since the transmitting component 21 is fixedly connected to the liquid dispenser 2, when the liquid dispenser 2 is used, the liquid dispenser 2 is only required to be held in a fixed posture, then the liquid outlet of the liquid dispenser 2 is aligned to the target sample hole, and the transmitting component 21 of the liquid dispenser 2 is aligned to the target receiving component, so that the sample in the liquid dispenser 2 can be smoothly added into the target sample hole, and the liquid dispenser signal is received by the target receiving component corresponding to the target sample hole.
When the liquid dispenser is used, the receiving components of all the sample holes are kept in an electrified state, and the emission component 21 is controlled to emit the modulated linearly-transmitted liquid-transferring signals, and as the emission component 21 is fixedly connected to the liquid dispenser 2, the liquid dispenser 2 is aligned to the target sample hole and the emission component 21 of the liquid dispenser 2 is aligned to the target receiving component, the samples in the liquid dispenser 2 can be smoothly added into the target sample hole and the liquid-transferring signals are received by the target receiving component corresponding to the target sample hole only by keeping the posture of holding the liquid dispenser 2 in a stable state.
In the embodiment of the application, when the sample is added to the sample hole, the control mode of the receiving component when the power is on or off is not limited.
Illustratively, the pipetting signal may be an optical signal, an acoustic signal, a radio signal, or the like, and the emitting assembly 21 may be a light emitter, an acoustic generator, a radio emitter, or the like, accordingly.
S130, responding to the received pipetting signals, and sending out target indication information by a target indication assembly corresponding to the target sample hole when the sample is added subsequently.
When the sample adding device is used, the received pipetting signals can be responded, and when the sample is added later, the target indication information is sent out through the target indication component corresponding to the target sample hole, so that the target sample hole to which the target sample is added can be indicated through the target indication information, and when the target sample is added to the sample hole, an operator can be prevented from adding the target sample into the sample hole 11 to which the target sample is added by mistake, and the prevention of the false sample adding is effectively realized.
As shown in fig. 2 and 3, in the structure, each sample hole 11 on the sample plate 1 corresponds to one indicating component 32, so that each sample hole 11 can be indicated by the indicating component 32 corresponding to each sample hole 11, after a sample has been added in the target sample hole, the target sample hole can be indicated to have the target sample added according to the target indication information corresponding to the pipetting signal, so that the subsequent erroneous addition of the sample in the target sample hole can be prevented, and the erroneous addition of the sample to the target sample hole can be prevented.
In use, the target indication information includes visible light, so that an operator can directly observe the target indication information, and accordingly, the indication assembly 32 can be a miniature or small LED lamp bead.
As shown in fig. 3, in the structure, the receiving component 31 and the indicating component 32 are both in columnar structures, and the receiving component 31 and the indicating component 32 are both arranged at the bottom of the sample plate 1 and between the adjacent sample holes 11, so that the receiving component 31 and the indicating component 32 can be prevented from interfering with the sample holes 11 when adding samples into the sample holes 11, the operability when adding samples can be improved, and the influence of visible light rays emitted by the indicating component 32 on the samples in the sample holes 11 can be avoided, so that the accuracy of the sample detection results can be ensured.
Illustratively, the top ends of the receiving component 31 and the indicating component 32 may abut against the plate body of the sample plate 1, so as to further avoid the influence of the receiving component 31 and the indicating component 32 on the sample.
The beneficial effect that foretell realization brought lies in, sends the pipetting signal through the transmission subassembly on the pipettor, and then can trigger target indication information through pipetting signal, and the operating personnel of being convenient for observe the target sample hole that has added the sample when the follow-up adds the sample, and then prevent to add the sample by mistake, can improve the convenience of the operation when preventing to add the sample by mistake, has simplified the operation process that prevents to add the sample by mistake, has improved the accuracy that prevents to add the sample by mistake.
The beneficial effect that foretell realization brought also lies in, and receiving element and instruction subassembly all locate the bottom of sample board and locate between the adjacent sample hole, and then can avoid receiving element and instruction subassembly to produce the interference to the sample hole when adding the sample to the sample hole, also can avoid the visible light that instructs the subassembly to send to produce the influence to the sample in the sample hole, guaranteed the degree of accuracy of test result.
In some implementations, the method further includes S111 to S113, and S111 to S113 are specifically described below.
S111, placing the sample plate 1 in the positioning flange 34 on the base 3. Wherein, the receiving component 31 and the indicating component 32 are arranged on the base 3, and each receiving component 31 and each indicating component 32 are respectively and electrically connected with the indicating control component 33.
As shown in fig. 3, in use, the positioning flange 34 on the base 3 is used to position the sample plate 1, and by placing the sample plate 1 in the positioning flange 34 on the base 3, the stability of the sample plate 1 can be improved when adding a sample to the sample plate 1.
Structurally, the receiving component 31 and the indicating component 32 are arranged on the base 3, so that the receiving component 31 and the indicating component 32 can be stably fixed, each receiving component 31 and each indicating component 32 can be connected to a PCB through pins, the PCB is electrically connected with the indicating control group mountain 33, and each receiving component 31 and each indicating component 32 of the indicating control component 33 can be electrically connected.
Fig. 4 is a schematic diagram showing an exploded front view of a method for preventing a sample from being erroneously applied in use according to an embodiment of the present application, as shown in fig. 4, in use, the sample plate 1 is simply placed in the positioning flange 34 on the base 3, and the gaps between each receiving component 31 and each indicating component 32 and the sample hole are aligned.
And S112, when a sample is added to the target sample hole of the sample plate 1, the emission component 21 on the liquid dispenser 2 is triggered to emit a liquid-transferring signal when the liquid dispenser 2 extrudes the sample.
When in use, in order to ensure the accuracy of the time when the pipetting signal is sent, when the sample is added to the target sample hole of the sample plate 1, the pipetting signal can be sent by the emitter component 21 on the pipettor 2 when the pipettor 2 extrudes the sample, so that the emitter component 21 can be ensured to send out the pipetting signal only when the pipettor 2 extrudes the sample, the electric energy used by the emitter component 21 can be saved, and the situation that the emitter component 21 continuously sends out the pipetting signal to cause the false triggering of the receiver component 31 to receive the pipetting signal can be avoided.
S113, the indication control component 33 stores the target number of the target sample hole, and controls the target indication component to send out target indication information according to the target number of the target sample hole.
When the device is used, each receiving component 31 can be numbered, and each sample hole 11 corresponds to one receiving component 31, so that when the receiving component 31 receives a pipetting signal, the target number of the target sample hole can be stored through the indication control component 33, and the target indication component is controlled to send target indication information according to the target number of the target sample hole, so that the sample hole added with the sample can be accurately indicated, and the repeated sample addition of the sample hole added with the sample can be avoided.
The beneficial effect that foretell realization mode brought lies in, triggers the emission subassembly on the pipettor simultaneously and sends the pipetting signal when extruding the sample through control pipettor, and then can guarantee that the emission subassembly only sends the pipetting signal when the sample is extruded to the pipettor, can practice thrift the electric energy that the emission subassembly used, also can avoid the emission subassembly to continuously send the pipetting signal and lead to the mistake to trigger receiving assembly to receive the pipetting signal, has improved the accuracy when emission subassembly and receiving assembly use.
The implementation mode has the advantages that the indication control component stores the target number of the target sample hole, and the target indication component is controlled to send target indication information according to the target number of the target sample hole, so that the sample hole added with the sample can be conveniently and accurately indicated.
In some implementations, the pipette 2 includes a housing 22, an extrusion lever 23 and a photoelectric switch 24, a power supply assembly 25 and a signal control assembly 26, the power supply assembly 25 and the signal control assembly 26 are fixedly connected within the housing 22, and the emitter assembly 21 is connected to the outer sidewall of a liquid tube ejection lever 27 of the pipette 2.
Fig. 5 is a schematic view of a partial cross-sectional structure of a pipette according to an embodiment of the present application, fig. 6 is a schematic view of a partial structure at B of the pipette of fig. 5, fig. 7 is a schematic view of a partial structure at C of the pipette of fig. 1, fig. 8 is a schematic view of a partial structure at D of the pipette of fig. 1, and as shown in fig. 5 to 8, the housing 22 is a holding structure of the pipette, and an operator holds the housing 22 to perform the operation of the pipette in use.
It should be noted that, the structure of the pipette 2 may be the same as that of the existing pipette, and the photoelectric switch 24, the power supply assembly 25 and the signal control assembly 26 are fixed in the pipette, and the embodiment of the application will not be repeated for the similar structure of the pipette 2 and the existing pipette.
Structurally, the extrusion rod 23 is slidably connected in the housing 22, the extrusion rod 23 is of a structure for sucking and extruding samples when the existing pipettor is operated, the extrusion rod 23 is connected with a piston, the piston is of a piston structure for directly sucking and extruding samples in the existing pipettor, and the extrusion rod 23 can be extruded to drive the piston of the pipettor to move so as to suck or discharge the samples out of the pipettor.
Structurally, the power supply assembly 25 and the signal control assembly 26 are fixedly connected in the housing 22, and thus the power supply assembly 25 and the signal control assembly 26 can be fixed and installed.
Structurally, the emitter assembly 21 is connected to the outer side wall of the liquid tube ejecting rod 27 of the liquid dispenser 2, the liquid tube ejecting rod 27 is used for pushing down the liquid suction nozzle of the liquid dispenser after the liquid suction nozzle is used, and the emitter assembly 21 is connected to the outer side wall of the liquid tube ejecting rod 27 of the liquid dispenser 2, so that the emitter assembly 21 is conveniently fixed, and simultaneously, a liquid transfer signal which is convenient for the receiver assembly 31 to receive is also conveniently sent out through the emitter assembly 21.
It should be noted that, the liquid tube ejecting lever 27 may be a liquid tube ejecting lever having the same structure as that of the existing pipettor, and the specific structure and working principle of the liquid tube ejecting lever will not be described again here.
In some implementations, a limiting flange 221 is disposed within the housing 22, and the optoelectronic switch 24 is fixedly connected to the limiting flange 221. The extruding rod 23 is provided with a baffle 231, the baffle 231 can trigger the photoelectric switch 24 when the extruding rod 23 extrudes a sample, and the transmitting component 21, the photoelectric switch 24 and the power supply component 25 are respectively and electrically connected with the signal control component 26.
Structurally, a limiting flange 221 is arranged in the shell 22, the limiting flange 221 is used for limiting the extrusion rod 23, and a limiting structure matched with the limiting flange 221 is arranged on the extrusion rod 23, so that the limiting flange 221 can limit the stroke of the extrusion rod 23, and the quantitative sample is sucked into or discharged out of the pipette by limiting the extrusion rod 23 to drive the piston of the pipette.
Structurally, as shown in fig. 5 and 6, the photoelectric switch 24 is fixedly connected to the limiting flange 221, the extruding rod 23 is provided with a baffle 231, the baffle 231 can shield the detection end of the photoelectric switch 24 when the extruding rod 23 extrudes a sample, so that the extruding rod 23 can trigger the photoelectric switch 24, and further the extruding rod 23 extrudes the sample to trigger the photoelectric switch 24, so that the photoelectric switch 24 receives information when the extruding rod 23 moves, and triggering of the photoelectric switch 24 when the sample is added is realized.
Structurally, it may be set that when the extrusion rod 23 moves to a position where the limiting flange 221 limits the extrusion rod 23, the extrusion rod 23 triggers the photoelectric switch 24, so that false triggering of the photoelectric switch 24 can be avoided.
It should be noted that, the relative positions of the baffle 23 and the photoelectric switch 24 are staggered in the transverse direction, so that the baffle 23 cannot be in direct contact with the photoelectric switch 24 when moving, the influence of the photoelectric switch 24 on the movement of the baffle 23 can be avoided, and the photoelectric switch 24 can accurately detect whether the baffle 23 moves to the detection end of the photoelectric switch 24 for detection.
When the device is used, the emission component 21, the photoelectric switch 24 and the power supply component 25 are respectively electrically connected with the signal control component 26, so that the emission component 21, the photoelectric switch 24 and the signal control component 26 can be powered through the power supply component 25, the signal control component 26 can control the working state of the emission component 21 according to the on state of the photoelectric switch 24, when the photoelectric switch 24 is connected and detects a moving signal of the extrusion rod 23, the signal control component 26 controls the emission component to emit a pipetting signal, and further, the pipetting signal can be emitted when a sample is added.
The implementation mode has the advantages that the photoelectric switch can be triggered by extruding the sample through the extruding rod, so that the photoelectric switch can detect the action when extruding the sample, the triggering of the photoelectric switch when adding the sample is realized, a pipetting signal is further sent out when adding the sample, the connection and detection of the photoelectric switch can be automatically realized, and the convenience of the pipettor in use is improved; and the emission component is only connected when the sample is added, so that the energy-saving effect of the pipette is improved.
The beneficial effect that foretell realization mode brought also lies in, detects the motion state of extruding the pole through photoelectric switch, can not produce the influence to extruding the motion and the stroke of pole, can guarantee to extrude the pole and freely move in the range of standard range, has avoided producing the influence to the precision of pipettor, has guaranteed the high accuracy use of pipettor.
In some implementations, the transmitting assembly 21 includes a connection base 211 and a transmitting head 212, the connection base 211 is fixedly connected to the liquid pipe ejecting rod 27, the transmitting head 212 is rotatably connected to the connection base 211, a wire plug terminal electrically connected to the signal control assembly 26 is provided on the housing 22, and the transmitting head 212 is electrically connected to the wire plug terminal through the wire plug terminal.
As shown in fig. 7 and 8, in structure, the emitting assembly 21 includes a connection base 211 and an emitting head 212, the connection base 211 is fixedly connected to the liquid tube ejecting rod 27, the emitting head 212 can be fixed through the connection base 211, and the emitting head 212 is rotatably connected to the connection base 211, so that the angle of the emitting head 211 can be adjusted.
Structurally, as shown in fig. 7 and 8, an adjusting bolt is connected to the connection base 211, and the connection base 211 can be pressed against and connected to the liquid tube ejecting rod 27 by the adjusting bolt, and the connection base 211 can be released from the liquid tube ejecting rod 27 by the adjusting bolt.
Structurally, the shell 22 is provided with a wire plugging terminal electrically connected with the signal control assembly 26, and the transmitting head 212 is electrically connected with the signal control assembly 26 through the wire plugging terminal, so that the signal control assembly 26 and the transmitting head 212 are conveniently and quickly connected and detached through the wire plugging terminal, and the transmitting assembly 21 is conveniently installed and detached.
The beneficial effect that foretell realization mode brought lies in, through rotating the transmitting head and connecting on the connecting seat, and then the angle of being convenient for adjust the transmitting head, can be according to the angle of user demand adjustment transmitting head, the transmission angle of the quick adjustment pipetting signal of being convenient for. Meanwhile, the transmitting head is electrically connected with the signal control assembly through the wiring terminal, the plug wire terminal and the signal control assembly, so that the transmitting head can be quickly installed and detached, and the transmitting head can be quickly replaced.
In some implementations, the signal control assembly 26 is provided with a plurality of kinds of buttons 261, the kinds of buttons 261 are arranged protruding the housing 22, and different kinds of buttons 261 are used for controlling the emission assembly 21 to emit pipetting signals corresponding to different sample kinds.
As shown in fig. 1 and 3, the plurality of kinds of buttons 261 are all protruded from the housing 22, and by pressing one kind of button 261 of the plurality of kinds of buttons 261, since different kinds of buttons 261 correspond to different kinds of pipetting signals of samples, the emission component 21 can be controlled to emit pipetting signals corresponding to the kinds of samples by pressing one kind of button 261.
In some implementations, fig. 10 is a flowchart of another method for preventing a sample from being added by mistake in the embodiment of the present application, and as shown in fig. 10, the method further includes S210 to S230, and S210 to S230 are specifically described below.
S210, when a target sample of a target sample type is added to the target sample hole of the sample plate 1, a target sample button corresponding to the target sample type is pressed, and the emission head 212 of the emission component 21 emits a target pipetting signal corresponding to the target sample type.
When different kinds of samples are added into the sample hole 11 of the sample plate 1 in use, when a target sample of a target sample kind is added into the target sample hole of the sample plate 1, a target sample button corresponding to the target sample kind can be pressed down, and the emission head 212 of the emission component 21 emits a target pipetting signal corresponding to the target sample kind, so that the erroneous addition of the target sample can be prevented when the target sample is added according to the target pipetting signal.
For example, when a sample of a type is added, a sample button corresponding to the sample of a type may be pressed, and the emitter head 212 of the emitter assembly 21 emits a pipetting signal corresponding to the sample of a type.
For example, when the sample types are different, the emission assembly 21 may be controlled to emit pipetting signals in the form of radio signals of different types.
It should be noted that, different sample types include samples with different batches, samples with different collection sources, and the like, and the method for classifying the sample types according to the embodiment of the present application is not limited.
S220, receiving a target pipetting signal by a target receiving component corresponding to the target sample hole.
When the device is used, the target pipetting signals are received through the target receiving components corresponding to the target sample holes, and then the target sample holes can be indicated according to the target pipetting signals received by the target receiving components.
S230, in response to the received target pipetting signal, the indication component 32 sends out target indication information corresponding to the target sample type when the sample is added subsequently. The target indication information corresponding to different target sample types corresponds to visible rays of different colors.
When the sample adding device is used, the received target pipetting signal is responded, the indication component 32 sends out target indication information corresponding to the target sample type when the sample is added later, so that corresponding target indication information can be sent out according to the target sample type when the sample is added later, further, the repeated sample adding is prevented when the sample is added, confusion of sample types when the sample is added can be avoided, and the mistaken sample adding of samples of different types can be prevented according to the sample types.
When the device is used, the target indication information corresponding to different target sample types corresponds to visible light rays of different colors, so that operators can observe the indication information corresponding to different sample types according to the visible light rays of different colors.
For example, the target indication information corresponding to different target sample types may correspond to visible rays of red, yellow, and blue, respectively.
The beneficial effect that foretell realization mode brought lies in, sends the pipetting signal that the sample kind corresponds through control emission subassembly, and then sends different instruction information through receiving pipetting signal that the sample kind corresponds, can instruct when the follow-up adds the sample according to different instruction information when adding the sample to operating personnel, can prevent to add the sample by mistake to different kinds of samples, and then avoid different kinds of samples to take place to confuse when adding, be fit for distinguishing the sample when adding multiple sample on the sample board, improved the result of use that prevents to add the sample by mistake.
In some implementations, the base 3 is provided with a pipetting sensor 35 electrically connected to the indication control unit 33, and the method further includes: when the pipetting detecting sensor 35 is not shielded, the indication components corresponding to all the sample wells do not send out target indication information. When the pipetting detecting sensor 35 is blocked, the target indicating assembly corresponding to the target sample hole to which the sample has been added emits target indicating information.
Fig. 11 is a schematic top view of a sample plate according to an embodiment of the present application, and fig. 12 is a schematic partial structure of an E-part of a pipette of fig. 11, and as shown in fig. 11 and 12, in the structure, a pipetting sensor 35 can detect whether an operator adds a sample above a base 3, and when adding the sample, an indication component is controlled to send out target indication information, so that electric energy can be saved, and the influence of sending out the target indication information for a long time on the sample can be avoided.
Illustratively, when the operator does not add a sample, the indication components corresponding to all sample holes do not emit target indication information when the operator's hand does not block the pipetting sensor 35, at which time electric energy can be saved and long-time emission of target indication information can be avoided to affect the sample.
Illustratively, when the operator does not add a sample, the indication components corresponding to all sample holes emit target indication information when the operator's hand shields the pipetting sensor 35, at which time erroneous addition of a sample can be prevented by the target indication information.
The beneficial effect that foretell realization mode brought lies in, through setting up the pipetting detects sensor, can practice thrift the electric energy and can be to avoiding sending target indication information for a long time to produce the influence to the sample, improved the intelligent degree when preventing the mistake and adding the sample.
In some implementations, the method further includes S310 to S320, and S310 to S320 are specifically described below.
S310, storing different sample areas corresponding to the sample holes 11 on the sample plate 1 in the indication control assembly 33, wherein receiving assemblies of the sample holes in the different sample areas correspond to different target pipetting signals, and indication assemblies of the sample holes in the different sample areas correspond to different target indication information; different target indication information corresponds to different colors of visible light.
In order to improve the detection efficiency of the sample when the samples of different types are detected at the same time, the samples of different types can be added to the same sample plate 1 for detection at the same time. In order to prevent the wrong addition of samples when different types of samples are added on the sample plate 1, different sample areas corresponding to the sample holes 11 on the sample plate 1 can be stored in the indication control component 33, the different sample areas are used for correspondingly adding different samples, the receiving components of the sample holes in the different sample areas correspond to different target pipetting information, further, different target pipetting signals can be received according to the receiving components of the sample holes in the different sample areas, the indicating components of the sample holes in the different sample areas correspond to different target indicating information, and further, different sample areas can be indicated according to the different target indicating information.
Fig. 13 is a schematic top view of a sample plate according to an embodiment of the present application, and as shown in fig. 13, the region of the sample plate 1 may be divided into a region 1A, a region 1B and a region 1C, and then different kinds of samples may be added to the region 1A, the region 1B and the region 1C, respectively.
Illustratively, different target indication information corresponds to different colors of visible light.
S320, when adding the target sample to the target sample hole of the target sample area of the sample plate 1, pressing the target sample button corresponding to the target pipetting signal of the target sample area, and the transmitting head 212 of the transmitting assembly 21 sends out the target pipetting signal corresponding to the target sample button.
In use, when a target sample is added to the target sample hole of the target sample area of the sample plate 1, a target sample button of a corresponding target pipetting signal of the target sample area is pressed, and the emission head 212 of the emission component 21 emits a target pipetting signal corresponding to the target sample button, so that the sample can be prevented from being added by mistake according to the target pipetting signal corresponding to the target sample button.
Illustratively, when the receiving component 31 in the sample area 1A can receive the a pipetting signals and the indicating component 32 in the sample area 1A can emit the a indicating information, the transmitting component 21 can be controlled to emit the a pipetting signals by pressing the target sample button a for controlling the transmitting component 21 to emit the a pipetting signals and the a pipetting signals can be received by the receiving component 31 in the sample area 1A.
S330, receiving a target pipetting signal by a target receiving component corresponding to a target sample hole of the target sample area.
When the anti-false-addition device is used, the target pipetting signal is received through the target receiving component corresponding to the target sample hole of the target sample area, and then the target sample hole can be indicated through the received target pipetting signal, so that the anti-false-addition of the sample is realized.
And S340, when the sample is added later, the target indication component corresponding to the target sample hole of the target sample area sends out target indication information corresponding to the target sample area.
When the method is used, when a target sample is added into the target sample hole in the target sample area, when the sample is added later, the target indication component corresponding to the target sample hole is controlled to send out target indication information corresponding to the target sample area, so that when the sample is added in different sample areas, the target indication component of the target sample hole with the added sample is controlled to send out target indication information corresponding to the target sample area, and the effect of preventing the false addition of the sample is further improved.
For example, when a sample is added to the sample hole in the area 1A, the target indication component corresponding to the target sample hole in the area 1A to which the sample has been added can be controlled to emit yellow visible light corresponding to the area 1A, so as to achieve the purpose of indicating the sample hole to which the sample has been added according to the area.
The implementation method has the beneficial effects that different target pipetting signals and target indication information are sent out according to different area control, the sample holes to which the target samples are added can be indicated according to the indication information corresponding to different areas, and further, when the samples are added later, the samples are prevented from being added by mistake according to the target indication information corresponding to the target sample areas, the samples corresponding to the samples in different areas are prevented from being added by mistake, and the purpose of preventing the samples from being added by mistake according to the areas is achieved.
In some implementations, the method further includes S410 to S420, and S410 to S420 are specifically described below.
S410, instructs the control module 33 to store the target addition pattern. The target adding mode comprises a continuous adding mode and a spacing adding mode, wherein the continuous adding mode corresponds to that all sample holes 11 in the sample area continuously add samples, and the spacing adding mode corresponds to that one sample hole 11 is reserved for every two sample holes 11 in the sample area to add samples.
In use, it may be desirable in some instances to add samples in different ways, so samples may be added in different modes of addition.
The target adding mode may include a continuous adding mode and an interval adding mode, where the continuous adding mode corresponds to adding samples continuously to all the sample holes 11 in the sample area, and the interval adding mode corresponds to adding samples to each two sample holes 11 in the sample area while leaving one sample hole 11 for adding samples, and thus samples may be added according to the continuous adding mode or the interval adding mode, in the interval adding mode, the gaps between the sample holes 11 may be increased, and the samples in adjacent sample holes 11 may be prevented from interfering with each other and affecting each other.
S420, when adding the target sample into the target sample hole, the instruction control component 33 controls the instruction component 32 to issue the target instruction information to instruct the target sample hole according to the target addition mode.
Illustratively, in the continuous addition mode, the indication control assembly 33 controls the indication assembly 32 to emit the target indication information to continuously indicate the target sample wells according to the continuous addition mode, thereby enabling an operator to add samples in adjacent sample wells 11 according to the target indication information.
Illustratively, in the interval adding mode, the interval adding mode corresponds to leaving one sample hole 11 for adding a sample in each two sample holes 11 in the sample area, and the indication control assembly 33 controls the indication assembly 32 according to the interval adding mode to control the indication assembly 32 to leave one sample hole 11 for each two sample holes 11 without sending out the target indication information, thereby indicating the target sample hole for adding a sample at intervals, so that an operator adds a sample at intervals between each two sample holes 11 according to the target indication information.
The implementation method has the beneficial effects that in the process of adding the sample in real time, the positions of the sample holes for the operators to add the sample are indicated according to different modes through the target indication information, so that the operators can be actively indicated to accurately add the sample according to different modes.
The beneficial effects brought by the implementation manner are that the above-mentioned S310 to S340 are combined, the results of adding samples to operators can be indicated in real time according to the target indication information control of different modes in different areas, the purposes of indicating the samples to be added to the sample holes in different areas when the samples are added to the sample holes in different areas are achieved, and the effect of preventing the samples from being added by mistake is further improved.
In some implementations, the method further includes: when the target sample area corresponding to the target sample hole stored by the indicating control component 33 is matched with the target sample area corresponding to the target pipetting information received by the target sample hole, or when the sample type information corresponding to the target pipetting information received by the target sample hole stored by the indicating control component 33 is matched with the sample type information corresponding to the target pipetting information received by the target sample hole, the indicating component 32 corresponding to the target sample hole emits visible light rays for sample matching, or the indicating control component 33 emits sound information for sample matching.
In the process of adding the sample in real time, if the sample is added by mistake, an operator can be prompted and the sample can be added by mistake, and further, the subsequent treatment can be performed by prompting the sample to be added by mistake.
In use, when the target sample area corresponding to the target sample hole stored by the indication control component 33 is matched with the target sample area of the target pipetting information received by the target sample hole, the target sample area corresponding to the target pipetting information added to the target sample in the target sample hole is matched with the target sample area corresponding to the target sample hole, and the region information of the added sample is described as correct, and the indication component 32 corresponding to the target sample hole can be controlled to emit visible light for sample matching so as to prompt an operator that the sample is added as correct.
In use, when the sample type information corresponding to the target sample hole stored in the instruction control component 33 matches with the sample type information of the target pipetting information received by the target sample hole, the sample type information indicating the target pipetting information received by the target sample hole matches with the sample type information corresponding to the target sample hole stored in the instruction control component 33, and the added sample type information is indicated to be correct at this time, the instruction control component 33 can be controlled to send out the sound information of sample matching so as to prompt the operator that the sample is added correctly.
In some implementations, the method further includes: when the target sample area corresponding to the target sample well stored by the indicating control unit 33 and the target sample area corresponding to the target pipetting information received by the target sample well do not match, or when the sample type information corresponding to the target sample well stored by the indicating control unit 33 and the sample type information corresponding to the target pipetting information received by the target sample well do not match, the indicating unit 32 corresponding to the target sample well emits visible light rays for sample mismatch, or the indicating control unit 33 emits sound information for sample mismatch.
Similarly, in the process of adding the sample in real time, when the area information of the added sample is wrong or the type information of the added sample is not matched and the sample is added in error, the indication component 32 corresponding to the target sample hole can be controlled to emit visible light rays of the sample not matched or the indication control component 33 can be controlled to emit sound information of the sample not matched so as to prompt an operator to carry out subsequent processing or mark the target sample hole with the sample added with errors.
The implementation mode has the beneficial effects that in the process of adding the sample in real time, when the area information or the type information of the added sample is correct, the operator can be prompted to add the sample, the target sample hole is marked when the sample is added in correct, the sample adding result of the target sample hole can be effectively indicated, the operator can identify and process the sample hole with the sample added by mistake, and the effect of preventing the sample from being added by mistake is further improved.
The embodiment of the application also provides a device for preventing the false addition of the sample, which comprises a sample plate 1, a liquid dispenser 2 and a base 3, wherein the base 3 is provided with a positioning flange 34 for positioning the sample plate 1, the liquid dispenser 2 is provided with a transmitting component 21 for transmitting a liquid-transferring signal, the base 3 is provided with a receiving component 31 and an indicating component 32, the receiving component 31 is used for receiving the liquid-transferring signal, and the indicating component 32 is used for transmitting indicating information according to the liquid-transferring signal, and the indicating information corresponds to the liquid-transferring signal.
As shown in fig. 1 to 4, the beneficial effects brought by the implementation manner are that the sample is contained through the sample plate 1, the positioning accuracy of the sample plate 1 can be guaranteed after the sample plate 1 is positioned on the base 3, the transmitting component 21 for sending out a pipetting signal is arranged on the pipettor 2, the receiving component 31 and the indicating component 32 are arranged on the base 3, the precision of the receiving component 31, the indicating component 32 and the sample plate 1 can be improved by the base 3, and then an operator can know the adding result of the sample according to the indicating information, so that the effect of preventing the mistakenly adding the sample is improved.
In some implementations, the method further includes: when the target sample area corresponding to the target sample hole stored by the indication control component 33 and the target sample area of the target pipetting information received by the target sample hole are not matched, or when the sample type information corresponding to the target sample hole stored by the indication control component 33 and the sample type information of the target pipetting information received by the target sample hole are not matched, the indication control component 33 stores the number corresponding to the target sample hole, and the indication component 32 corresponding to the target sample hole sends out the mistakenly-added sample indication information when the sample is added subsequently, wherein the mistakenly-added sample indication information comprises visible light rays with different colors from the target indication information.
When the target sample area corresponding to the target sample hole stored by the indication control component 33 is not matched with the target sample area of the target pipetting information received by the target sample hole, the fact that the target sample area of the target pipetting information corresponding to the target sample added into the target sample hole is not matched with the target sample area corresponding to the target sample hole is indicated, at the moment, the region information of the added sample is wrong, after the sample is mistakenly added, the indication component 33 stores the corresponding number of the target sample hole, and sends out mistakenly added sample indication information to the indication component 32 corresponding to the target sample hole when the sample is subsequently added, the mistakenly added sample indication information comprises visible light rays with different colors from the target indication information, the indication control component 33 can store the mistakenly added sample information, and can prompt the mistakenly added sample according to the visible light rays with different colors from the mistakenly added sample indication information when the sample is subsequently added, the position of the sample hole where the mistakenly added sample occurs can be displayed in real time, the intelligent degree of prompting after the mistakenly added sample is improved, and an operator can be reminded of timely processing the sample hole of the mistakenly added sample.
When the sample type information corresponding to the target sample hole stored by the indication control component 33 is not matched with the sample type information of the target pipetting information received by the target sample hole, the sample type information of the target pipetting information received by the target sample hole is not matched with the sample type information corresponding to the target sample hole stored by the indication control component 33, at the moment, the added sample type information is wrong, after the sample is mistakenly added, the indication component 33 stores the number corresponding to the target sample hole, and sends out mistakenly added sample indication information to the indication component 32 corresponding to the target sample hole when the sample is subsequently added, the mistakenly added sample indication information comprises visible light rays with different colors from the target indication information, the mistakenly added sample information can be stored by the indication control component 33, and the mistakenly added sample can be indicated according to the mistakenly added sample indication information pair and the visible light rays with different colors from the target indication information when the sample is subsequently added.
The beneficial effect that the realization mode brought above is that after the mistake adds the sample, can store the information of mistake and add the sample through instruction control assembly 33 to can be according to the mistake and add the sample instruction information to the suggestion to the mistake with the different visible light of the colour of target instruction information when adding the sample in the follow-up, improved the intelligent degree to the suggestion after the mistake adds the sample, improved the suggestion effect to the sample hole of mistake and added the sample.
The implementation mode has the beneficial effects that after the sample is added by mistake, the target sample hole can be continuously prompted that the sample is added by mistake when the sample is added later, the single result of the sample added by mistake can be stored, and the result storage and the intelligent degree of prompt of the sample added by mistake are improved.
In some implementations, the method further includes:
s510, storing the sample plate information of the sample plate 1 and the sample addition information of all the sample wells 11 on the sample plate 1, and uploading the sample plate information and the sample addition information to the server.
When the sample plate is used, the sample plate information of the sample plate 1 and the sample addition information of all the sample holes 11 on the sample plate 1 are stored, so that the sample detection result can be intelligently analyzed and processed according to the sample plate information of the sample plate 1 and the sample addition information of all the sample holes 11 on the sample plate 1, the sample plate information and the sample addition information are uploaded to a server, and the sample plate information of the sample plate 1 and the sample addition information of all the sample holes 11 on the sample plate 1 can be conveniently subjected to data processing.
S520, when the first sample Kong Wu is added, discarding the sample detection results in all the sample wells 11 around the first sample well on the sample plate 1, and storing the pipetting signals of the first sample well on the sample plate 1 and the numbers of all the sample wells 11 around the first sample well on the sample plate 1.
When the first sample Kong Wu is detected by the method, the samples in the sample holes 11 after the samples are added by mistake may affect the test results of the sample holes 11 around the first sample holes, so that the sample detection results in all the sample holes 11 around the first sample holes on the sample plate 1 can be discarded, further, the influence on the accuracy of the sample detection results after the samples in the sample holes 11 after the samples are added by mistake affect the results of the sample holes 11 around the first sample holes can be avoided, and the accuracy of the sample detection results is improved.
When in use, the pipetting signals of the first sample hole on the sample plate 1 and the numbers of all the sample holes 11 around the first sample hole on the sample plate 1 are stored simultaneously, so that the information of the samples added in the first sample hole and the information of the samples added in all the sample holes 11 around the first sample hole can be obtained according to the pipetting signals of the first sample hole on the sample plate 1 and the numbers of all the sample holes 11 around the first sample hole on the sample plate 1, thereby facilitating the follow-up re-assay of the samples added in the first sample hole and the samples added around all the sample holes 11 around the first sample hole.
The implementation method has the beneficial effects that the accuracy of the overall result of the sample detection can be improved by removing the test result of the first sample hole with the erroneously added sample and removing the test result of the sample holes around the first sample hole with the erroneously added sample.
The implementation method has the beneficial effects that the serial numbers of the first sample holes for the mistakenly added samples and the serial numbers of all the sample holes around the first sample holes on the sample plate are stored, so that the samples which should be added in the first sample holes for the mistakenly added samples and the samples which should be added around all the sample holes around the first sample holes are conveniently and efficiently tested, and the tests on all the samples are conveniently and accurately completed.
The foregoing description of the preferred embodiments of the application is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the application.

Claims (10)

1. A method for preventing misaddition of a sample, the method comprising:
when a target sample is added to a target sample hole of the sample plate (1), a transmitting component (21) on the liquid dispenser (2) sends out a liquid-transferring signal;
The target receiving assembly corresponding to the target sample hole receives the pipetting signal;
responding to the received pipetting signals, and sending out target indication information by a target indication component corresponding to the target sample hole when a sample is added subsequently; the target indication information comprises visible rays;
the sample plate (1) is of a transparent structure, a plurality of sample holes (11) are formed in the sample plate (1), each sample hole (11) in the sample plate (1) corresponds to one receiving component (31) and one indicating component (32), and the receiving component (31) and the indicating components (32) are all arranged at the bottom of the sample plate (1) and between the adjacent sample holes (11).
2. The method for preventing misaddition of a sample according to claim 1, wherein the method further comprises:
placing the sample plate (1) in a positioning flange (34) on a base (3); wherein the receiving assembly (31) and the indicating assembly (32) are arranged on the base (3), and each receiving assembly (31) and each indicating assembly (32) are respectively and electrically connected with the indicating control assembly (33);
when a sample is added to a target sample hole of the sample plate (1), triggering a transmitting component (21) on the liquid dispenser (2) to send out the liquid-transferring signal when the liquid dispenser (2) extrudes the sample;
The indication control component (33) stores the target number of the target sample hole and controls the target indication component to send out the target indication information according to the target number of the target sample hole.
3. The method for preventing false addition of a sample according to claim 2, wherein the pipette (2) comprises a housing (22), an extrusion rod (23) and a photoelectric switch (24), a power supply assembly (25) and a signal control assembly (26), wherein the extrusion rod (23) is slidably connected in the housing (22), the power supply assembly (25) and the signal control assembly (26) are fixedly connected in the housing (22), and the emission assembly (21) is connected on the outer side wall of a liquid tube ejection rod (27) of the pipette (2);
a limiting flange (221) is arranged in the shell (22), and the photoelectric switch (24) is fixedly connected to the limiting flange (221); be equipped with baffle (231) on extruding rod (23), extrude when rod (23) extrude the sample baffle (231) can trigger photoelectric switch (24), emission subassembly (21) photoelectric switch (24) power supply unit (25) respectively with signal control unit (26) electricity is connected.
4. A method for preventing false addition of a sample according to claim 3, characterized in that the emitter assembly (21) comprises a connection seat (211) and an emitter head (212), the connection seat (211) is fixedly connected to the liquid tube ejecting rod (27), the emitter head (212) is rotatably connected to the connection seat (211), a wire plug terminal electrically connected to the signal control assembly (26) is provided on the housing (22), and the emitter head (212) is electrically connected to the wire plug terminal through a wire connection terminal.
5. A method for preventing false addition of samples as claimed in claim 4, characterized in that the signal control assembly (26) is provided with a plurality of kinds of buttons (261), the kinds of buttons (261) being arranged to protrude from the housing (22), different kinds of buttons (261) being used to control the emission assembly (21) to emit pipetting signals corresponding to different kinds of samples, the method further comprising:
when a target sample of a target sample type is added to a target sample hole of a sample plate (1), a target sample button corresponding to the target sample type is pressed, and a target pipetting signal corresponding to the target sample type is emitted by the emission head (212) of the emission component (21);
a target receiving component corresponding to the target sample hole receives the target pipetting signal;
in response to the received target pipetting signal, the indication component (32) emits target indication information corresponding to the target sample type when a sample is subsequently added; the target indication information corresponding to different target sample types corresponds to visible rays of different colors.
6. Method for preventing false addition of a sample according to claim 5, characterized in that the base (3) is provided with a pipetting sensor (35) electrically connected to the indication control assembly (33), the method further comprising:
When the pipetting detection sensor (35) is not shielded, the indication components corresponding to all sample holes do not send out the target indication information; when the pipetting detecting sensor (35) is shielded, the target indicating component corresponding to the target sample hole to which the sample has been added sends out the target indicating information.
7. The method for preventing misaddition of a sample of claim 6, further comprising:
storing different sample areas corresponding to the sample holes (11) on the sample plate (1) in the indication control assembly (33), wherein receiving assemblies of the sample holes in the different sample areas correspond to different target pipetting signals, and indication assemblies of the sample holes in the different sample areas correspond to different target indication information; different target indication information corresponds to different colors of visible rays;
when adding a target sample to a target sample hole of a target sample area of a sample plate (1), pressing a target sample button corresponding to a target pipetting signal corresponding to the target sample area, and sending the target pipetting signal corresponding to the target sample button by the transmitting head (212) of the transmitting component (21);
a target receiving component corresponding to a target sample hole of the target sample area receives a target pipetting signal;
And when the sample is added later, the target indication component corresponding to the target sample hole of the target sample area sends out target indication information corresponding to the target sample area.
8. The method for preventing misaddition of a sample of claim 7, further comprising:
storing a target addition pattern within the indication control component (33); the target adding mode comprises a continuous adding mode and an interval adding mode, wherein the continuous adding mode corresponds to all sample holes (11) in the sample area for continuously adding samples, and the interval adding mode corresponds to the step of reserving one sample hole (11) for adding samples for every two sample holes (11) in the sample area;
when adding a target sample into a target sample hole, the indication control component (33) controls the indication component (32) to send out target indication information to indicate the target sample hole according to the target addition mode.
9. The method for preventing misaddition of a sample of claim 8, further comprising:
when a target sample area corresponding to a target sample hole stored by the indication control component (33) is matched with a target sample area corresponding to target pipetting information received by the target sample hole, or when the sample type information corresponding to the target sample hole stored by the indication control component (33) is matched with the sample type information corresponding to the target pipetting information received by the target sample hole, an indication component (32) corresponding to the target sample hole sends out visible light rays for sample matching, or the indication control component (33) sends out sound information for sample matching;
When the target sample area corresponding to the target sample hole stored by the indication control component (33) and the target sample area corresponding to the target pipetting information received by the target sample hole are not matched, or when the sample type information corresponding to the target sample hole stored by the indication control component (33) and the sample type information corresponding to the target pipetting information received by the target sample hole are not matched, the indication component (33) corresponding to the target sample hole emits visible light with a sample being not matched, or the indication control component (33) emits sound information with a sample being not matched.
10. The utility model provides a device for preventing mistake adds sample, its characterized in that includes sample board (1), pipettor (2) and base (3), be equipped with on base (3) and be used for right locating flange (34) of sample board (1) location, be equipped with on pipettor (2) and be used for sending emitter module (21) of pipetting signal, be equipped with receiver module (31) and indicator module (32) on base (3), receiver module (31) are used for receiving pipetting signal, indicator module (32) are used for according to pipetting signal sends the indication information, the indication information with pipetting signal corresponds.
CN202311187001.7A 2023-09-14 2023-09-14 Method and apparatus for preventing misaddition of sample Pending CN117214448A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311187001.7A CN117214448A (en) 2023-09-14 2023-09-14 Method and apparatus for preventing misaddition of sample

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202311187001.7A CN117214448A (en) 2023-09-14 2023-09-14 Method and apparatus for preventing misaddition of sample

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Publication Number Publication Date
CN117214448A true CN117214448A (en) 2023-12-12

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CN202311187001.7A Pending CN117214448A (en) 2023-09-14 2023-09-14 Method and apparatus for preventing misaddition of sample

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