CN1171958A - Health-care oral liquid - Google Patents

Health-care oral liquid Download PDF

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Publication number
CN1171958A
CN1171958A CN 97111921 CN97111921A CN1171958A CN 1171958 A CN1171958 A CN 1171958A CN 97111921 CN97111921 CN 97111921 CN 97111921 A CN97111921 A CN 97111921A CN 1171958 A CN1171958 A CN 1171958A
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liquid
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gram
oral liquid
hours
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CN 97111921
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CN1054073C (en
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吴炳新
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济南三株药业有限公司
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Abstract

The oral liquid is a mixed liquid prepared by fermenting Chinese herbal medicine extract, protein enzymolysis complex liquid, crystal sugar, glucose, mineral salt, yeast extract, black bean germ conversion protein liquid and bifidobacterium and lactobacillus acidophilus, and has unique effects of improving sexual function, enhancing immunity and regulating microecological balance.

Description

A kind of health care oral liquid
The present invention relates to a kind of health care oral liquid, specifically be a kind of be the oral liquid that main component is prepared from the extracts of Chinese herbal medicine, belong to the Medicines and Health Product field.
Along with the raising of people's living standard, more and more be urgent for the demand of health care.Health product of a great variety have just appearred on the market thereupon.Wherein occupied the suitable share in market based on the health product of kidney invigorating and YANG supporting.Because old people's body constitution descends gradually, at this stage majority based on yang deficiency, so the kidney supplementing yang invigorating health care product have certain treatment meaning for the health care of middle-aged and elderly people.Yet kidney-nourishing yang-strengthening medicine is the product of some warm-dryness syndrome after all, and it is improper to take, on the contrary impairment of YIN.Quite a few middle-aged and elderly people is particularly arranged, and its body constitution also shows the deficiency of YIN to a certain degree in yang deficiency, and these people are not suitable for taking simple medea.Therefore, invent a kind of the kidney invigorating medicine of tonifying both YIN and YANG, can satisfy these crowds' demand.
Also have a kind of microbial ecological agent health product on the market, this health preparation is for improving body immunity, and the microecosystem regulation balance has good health-care effect.But this preparation effect is single, can not satisfy the health care demand of the middle-aged and elderly people of suffering from a deficiency of the kidney.Up to the present, do not see as yet kidney-reinforcing drug and the compound comprehensive health care's product that are prepared from of microbial ecological agent.
The object of the invention provides a kind of health care oral liquid with effect of the kidney invigorating and essence nourishing, body-building tonifying YANG, slow down aging, promotion immunologic function and sexual function improvement.
Health care oral liquid of the present invention is to ferment and the fermentation liquid mixture for preparing with following component:
Extracts of Chinese herbal medicine 8-12%
Protein digestion complex liquid 8-12%
Crystal sugar 8-12%
Glucose 1-3%
Mineral salt 1-3%
Yeast extract 0.3-1%
Semen sojae atricolor plumule transforming protein liquid adds 100%
Above-mentioned fermentation is that zymocyte is fermented with bacillus bifidus, bacillus acidophilus.Zymogenic addition is by 1% inoculation fermentation with bacillus bifidus, 12 hours inmature culture of bacillus acidophilus.
The fermentating liquid PH value that makes is 6.8-7.0.
Described extracts of Chinese herbal medicine is the extracting solution with following raw material and method preparation:
Raw material (in the contained crude drug amount of per 100 milliliters of extracting solution)
Radix Astragali 15-25 gram
Fructus Lycii 15-25 gram
Herba Epimedii 8-12 gram
Semen Allii Tuberosi 8-14 gram
Mytilus 6-10 gram
Radix Ginseng 4-8 gram
Herba Cistanches 10-20 gram
Fructus Crataegi 10-20 gram
Radix Glycyrrhizae 1-5 gram
The above-mentioned raw materials proportion optimization is:
The Radix Astragali 20 grams
Fructus Lycii 20 grams
Herba Epimedii 10 grams
Semen Allii Tuberosi 12 grams
Mytilus 9 grams
Radix Ginseng 6 grams
Herba Cistanches 14 grams
Fructus Crataegi 16 grams
Radix Glycyrrhizae 2 grams
With above nine flavors, Radix Ginseng 95% ethanol, reflux, extract, 8 hours reclaims ethanol, and medicinal liquid is standby.8 flavor Chinese medicines such as Radix Ginseng residue and Herba Epimedii decoct with water three times, 1.5 hours for the first time, 1 hour for the second time, 0.5 hour for the third time, above-mentioned medicinal liquid merges, and filters, and filtrate is concentrated to relative density when being 1.03-1.04 (80-90 ℃), add the panaxynol extracting solution, decompression continue to be concentrated into 100 milliliters standby.
The preparation of described protein digestion complex liquid:
The protein digestion complex liquid is that to select high-quality beef and mutton (comprising male genitalia) for use be raw material, meat paste is made in rubbing, after being heating and curing more than 80 ℃, add trypsin and in 40 ℃ thermal environment, be incubated 10-15 minute, fully the digestion hydrolysis was made through 12 hours, and tryptic addition adds according to the conventional amount used of proteolysis.
Described yeast extract is that to select fresh yeast (or dry yeast) for use be raw material, adds water to make suspension, and under 40 ℃ of temperature conditions, short its self-dissolving is condensed into paste from solution through 100 ℃ of heating.
Described mineral salt comprises:
100 milligrams in magnesium sulfate
4 milliliters of saturated ionized calcium liquid (containing 900 milligrams of activated calciums)
100 milligrams of dipotassium hydrogen phosphates
100 milligrams of potassium dihydrogen phosphates
1 milligram in sodium chloride
The preparation of described Semen sojae atricolor transforming protein liquid:
Semen sojae atricolor transforming protein liquid is that to select the high-quality Semen sojae atricolor for use be raw material, through water logging, hatch the generation plumelet, adds water and is made into 30% concentration, and 100 ℃ of heating decocted in 30 minutes makes.
Fermentation liquid preparation process of mixture of the present invention is:
Above each component and carbohydrate are added by said ratio, add 100% with transforming protein liquid, 120 ℃ of sterilizations behind the mix homogeneously are cooled to about 40 ℃, add zymocyte, keep 39 ± 1 ℃ of fermentations of temperature 18 hours, 60 ℃ of deactivations are after 3 hours, 40 ℃ of packing, sampling inspection is qualified, warehouse-in.
Chinese medicine is thought: " YIN and YANG in a relative equilibrium, life activities being normally maintained." health preparation of the present invention selects warming the kidney to invigorate YANGs such as Herba Epimedii, Mytilus, Herba Cistanches for use, nourishing kidney yins such as Fructus Lycii get cloudy helping with sun; Be aided with Radix Ginseng, the Radix Astragali with QI invigorating, the Folium Allii tuberosi seed to be to activate yang, i.e. Jing-Yue Complete Works what is called " kind YANG invigorating person must be in treating YANG within YIN, then positive cloudy helping and biochemical infinite ", and product nourishing YIN tonifying YANG of the present invention develops simultaneously, thereby the kidney warming replenishing essence effect is arranged.
Product of the present invention is a raw material with nutritious foods such as protein digestion complex liquid, yeast extract simultaneously, is under little ecological theory instructs, and adopts modern biotechnology, the new type of health ecological agent of selecting for use the fermentation of human body beneficial bacterium to make.Product of the present invention is a compound basis with little ecological theory, Chinese medicine and pharmacy theory, threpsology's theory, and complementary advantage has unique effect to sexual function improving, raising immunity, microecosystem regulation balance.
Through zoopery and the test of human body examination clothes, show to have following effect:
1, irritate stomach for 40 milliliters/kg of castration mouse oral liquid of the present invention, once a day, administration 12 days can make its accessory sex organ-prostate and seminal vesicle weight in wet base increase, and illustrates that product of the present invention has the effect of androgen sample.
2, product of the present invention can make its deficient syndrome symptom improve to the yang deficiency syndrome mice that hydrocortisone causes.Mice autonomic activities result of the test shows, can improve yang deficiency syndrome mice autonomic activities number of times, prolongs the low temperature swimming time, illustrates that product of the present invention has certain strong effect.
3, male mice mating ability result of the test shows, product oral liquid of the present invention (30ml/kg) is given two weeks of mouse stomach, can obviously shorten and catch incubation period and improve the seizure number of times, illustrates and product year of the present invention obviously improves the mating ability of male mice.
4, product of the present invention can make the Turnover of Mouse Peritoneal Macrophages phagocytic percentage and the phagocytic index of hydrocortisone inhibition immunologic function obviously increase, and illustrates that this medicine has certain facilitation to immunologic function.
5, product of the present invention can make hydrocortisone cause the deficient syndrome depletion state of yang deficiency mice to make moderate progress, and reduces dead mouse, and can improve mouse blood SOD vigor, illustrates that product of the present invention has certain anti-aging effects.
6, through the test of 240 routine human bodies examination clothes, before product oral liquid of the present invention is drunk the back and is drunk the every symptom of experimenter be improved significantly, with matched group relatively, the remarkable meaning of difference army mail.After its gonadal hormone of experimenter T (testosterone) drinks raising is also arranged, contrast difference's significance before and after self.Show that middle-aged and elderly people drank product oral liquid of the present invention 1 month continuously, get final product physical strength reinforcing, sexual function improving.
Embodiment
Prescription:
Extracts of Chinese herbal medicine 10%
Protein digestion complex liquid 10%
Crystal sugar 10%
Glucose 1.5%
Mineral salt 1.2%
Yeast extract 0.6%
Semen sojae atricolor plumule transforming protein liquid adds 100%.
1, the preparation of extracts of Chinese herbal medicine:
Choose raw material in the contained crude drug amount of per 100 milliliters of extracting solution according to following dosage
The Radix Astragali 20 grams
Fructus Lycii 20 grams
Herba Epimedii 10 grams
Semen Allii Tuberosi 12 grams
Mytilus 9 grams
Radix Ginseng 6 grams
Herba Cistanches 14 grams
Fructus Crataegi 16 grams
Radix Glycyrrhizae 2 grams
With above nine flavors, Radix Ginseng 95% ethanol, reflux, extract, 8 hours reclaims ethanol, and medicinal liquid is standby.8 flavor Chinese medicines such as Radix Ginseng residue and Herba Epimedii decoct with water three times, 1.5 hours for the first time, 1 hour for the second time, 0.5 hour for the third time, above-mentioned medicinal liquid merges, and filters, and filtrate is concentrated to relative density when being 1.03-1.04 (80-90 ℃), add the panaxynol extracting solution, decompression continue to be concentrated into 100 milliliters standby.
2, the preparation of protein digestion complex liquid:
Selecting high-quality beef and mutton (comprising male genitalia) for use is raw material, rubs to make meat paste, after being heating and curing more than 80 ℃, adds trypsin and be incubated 10-15 minute in 40 ℃ thermal environment, and fully the enzymolysis complex liquid was made in the digestion hydrolysis through 12 hours.
3, the preparation of yeast extract:
Selecting fresh yeast (or dry yeast) for use is raw material, adds water to make suspension, and under 40 ℃ of temperature conditions, short its self-dissolving is condensed into paste from solution through 100 ℃ of heating.
4, mineral salt preparation:
100 milligrams in magnesium sulfate
4 milliliters of saturated ionized calcium liquid (containing 900 milligrams of activated calciums)
100 milligrams of dipotassium hydrogen phosphates
100 milligrams of potassium dihydrogen phosphates
1 milligram in sodium chloride
Mix homogeneously.
5, the preparation of Semen sojae atricolor transforming protein liquid:
Selecting the high-quality Semen sojae atricolor for use is raw material, through water logging, hatch the generation plumelet, adds water and is made into 30% concentration, and 100 ℃ of heating decocted in 30 minutes makes.
6, the preparation of oral liquid:
Above each component and carbohydrate are added by said ratio, add 100% with transforming protein liquid, 120 ℃ of sterilizations behind the mix homogeneously, be cooled to about 40 ℃, bacillus bifidus, 12 hours inmature culture of bacillus acidophilus by 1% inoculation fermentation, are kept 39 ± 1 ℃ of fermentations of temperature 18 hours, 60 ℃ of deactivations are after 3 hours, 40 ℃ of packing, sampling inspection is qualified, warehouse-in.

Claims (5)

1, a kind of health care oral liquid is characterized in that this oral liquid is the fermentation mixed liquor with following composition preparation:
Extracts of Chinese herbal medicine 8-12%
Protein digestion complex liquid 8-12%
Crystal sugar 8-12%
Glucose 1-3%
Mineral salt 1-3%
Yeast extract 0.3-1%
Semen sojae atricolor plumule transforming protein liquid adds 100%
Zymocyte is bacillus bifidus and bacillus acidophilus;
Wherein extracts of Chinese herbal medicine is the aqueous extract of following Chinese herbal medicine, and consumption is in the contained crude drug amount of per 100 milliliters of extracting solution:
Radix Astragali 15-25 gram
Fructus Lycii 15-25 gram
Herba Epimedii 8-12 gram
Semen Allii Tuberosi 8-14 gram
Mytilus 6-10 gram
Radix Ginseng 4-8 gram
Herba Cistanches 10-20 gram
Fructus Crataegi 10-20 gram
Radix Glycyrrhizae 1-5 gram
The preparation of above-mentioned protein digestion complex liquid:
Selecting the high-quality beef and mutton for use is raw material, rubs to make meat paste, after being heating and curing more than 80 ℃, adds trypsin and be incubated 10-15 minute in 40 ℃ thermal environment, and fully the digestion hydrolysis was made through 12 hours;
The preparation of above-mentioned yeast extract is that to select fresh yeast for use be raw material, adds water and makes suspension, and under 40 ℃ of temperature conditions, short its self-dissolving is condensed into paste from solution through 100 ℃ of heating;
Described mineral salt comprises:
100 milligrams in magnesium sulfate
4 milliliters of saturated ionized calcium liquid that contain 900 milligrams of activated calciums
100 milligrams of dipotassium hydrogen phosphates
100 milligrams of potassium dihydrogen phosphates
1 milligram in sodium chloride;
The preparation of described Semen sojae atricolor transforming protein liquid:
Selecting the high-quality Semen sojae atricolor for use is raw material, through water logging, hatch the generation plumelet, adds water and is made into 30% concentration, and 100 ℃ of heating decocted in 30 minutes makes.
2,, it is characterized in that described extracts of Chinese herbal medicine extracts with following method according to the oral liquid of claim 1:
Radix Ginseng 95% ethanol, reflux, extract, 8 hours reclaims ethanol, medicinal liquid is standby, other 8 flavor Chinese medicines such as Radix Ginseng residue and Herba Epimedii decoct with water three times, and 1.5 hours for the first time, 1 hour for the second time, 0.5 hour for the third time, medicinal liquid merges, and filters, and it is that 80-90 ℃ of heat is when surveying 1.03-1.04 that filtrate is concentrated to relative density, add the panaxynol extracting solution, decompression continue to be concentrated into 100 milliliters standby.
3, oral liquid according to claim 2 is characterized in that described herbal raw material proportioning is:
The Radix Astragali 20 grams
Fructus Lycii 20 grams
Herba Epimedii 10 grams
Semen Allii Tuberosi 12 grams
Mytilus 9 grams
Radix Ginseng 6 grams
Herba Cistanches 14 grams
Fructus Crataegi 16 grams
Radix Glycyrrhizae 2 grams.
4,, it is characterized in that this oral liquid prepares with following method according to the oral liquid of claim 1:
Described each component and carbohydrate are added by described proportioning, add 100% with Semen sojae atricolor plumule transforming protein liquid, 120 ℃ of sterilizations behind the mix homogeneously, be cooled to about 40 ℃, add bacillus bifidus, 12 hours inmature culture of bacillus acidophilus,, keep 39 ± 1 ℃ of fermentations of temperature 18 hours by 1% inoculation fermentation, 60 ℃ of deactivations are after 3 hours, 40 ℃ of packing.
5, oral liquid according to claim 1 is characterized in that described yeast extract is feedstock production with the dry yeast.
CN97111921A 1997-07-03 1997-07-03 Health-care oral liquid Expired - Fee Related CN1054073C (en)

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CN97111921A CN1054073C (en) 1997-07-03 1997-07-03 Health-care oral liquid

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CN1171958A true CN1171958A (en) 1998-02-04
CN1054073C CN1054073C (en) 2000-07-05

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100378226C (en) * 2002-12-05 2008-04-02 弘林通产株式会社 Ginseng fermented by lactic acid bacterium, yoghurt containing the same, and lactic acid bacteria used in the preparation thereof
CN103719605A (en) * 2013-12-21 2014-04-16 安徽惠尔普生物科技发展有限责任公司 Traditional Chinese medicine biological fermentation liquid feed for enhancing boar semen quality
CN105935404A (en) * 2016-05-31 2016-09-14 上海华颜医药科技有限公司 Traditional Chinese medicine fermentation medium with anti-ageing function, and preparation method of fermentation preparation

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078354B (en) * 2011-01-21 2012-08-22 吉林紫鑫药物研究有限公司 Medicine composition capable of improving immunity and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100378226C (en) * 2002-12-05 2008-04-02 弘林通产株式会社 Ginseng fermented by lactic acid bacterium, yoghurt containing the same, and lactic acid bacteria used in the preparation thereof
CN103719605A (en) * 2013-12-21 2014-04-16 安徽惠尔普生物科技发展有限责任公司 Traditional Chinese medicine biological fermentation liquid feed for enhancing boar semen quality
CN105935404A (en) * 2016-05-31 2016-09-14 上海华颜医药科技有限公司 Traditional Chinese medicine fermentation medium with anti-ageing function, and preparation method of fermentation preparation
CN105935404B (en) * 2016-05-31 2021-04-27 上海华颜医药科技有限公司 Traditional Chinese medicine fermentation medium with anti-aging function and preparation method of fermentation preparation

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