CN117194999A - Similarity determination method and device for radiotherapy plan, electronic equipment and storage medium - Google Patents

Similarity determination method and device for radiotherapy plan, electronic equipment and storage medium Download PDF

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Publication number
CN117194999A
CN117194999A CN202311175065.5A CN202311175065A CN117194999A CN 117194999 A CN117194999 A CN 117194999A CN 202311175065 A CN202311175065 A CN 202311175065A CN 117194999 A CN117194999 A CN 117194999A
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radiotherapy
plan
radiotherapy plan
similarity
feature
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周琦超
冷子轩
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Manteia Data Technology Co ltd In Xiamen Area Of Fujian Pilot Free Trade Zone
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Manteia Data Technology Co ltd In Xiamen Area Of Fujian Pilot Free Trade Zone
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Abstract

The application discloses a method, a device, electronic equipment and a storage medium for determining similarity of a radiotherapy plan. Wherein the method comprises the following steps: acquiring first characteristics corresponding to a first radiotherapy plan, wherein the first characteristics are used for representing distance information from each radioactive source to each first organ in N first organs in portal information formulated by the first radiotherapy plan; acquiring second characteristics corresponding to a second radiotherapy plan, wherein the second characteristics are used for representing distance information from each radioactive source to each second organ in M second organs in portal information formulated by the second radiotherapy plan; and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first characteristic and the second characteristic. The application solves the technical problem that the similarity determination of the radiotherapy plan is inaccurate caused by comparing the similarity of the radiotherapy plan according to the image characteristics in the prior art.

Description

Similarity determination method and device for radiotherapy plan, electronic equipment and storage medium
Technical Field
The application relates to the field of medical science and technology, in particular to a method and device for determining similarity of radiotherapy plans, electronic equipment and a storage medium.
Background
In the medical science and technology field, especially in the radiation therapy technical field, it is often necessary to compare the similarity of two radiotherapy plans, for example, when evaluating one target radiotherapy plan corresponding to a target object, it is necessary to compare the similarity of the target radiotherapy plan and the historical radiotherapy plan of the target object.
However, in the prior art, when comparing the similarity of the radiotherapy plans, the similarity determination of the radiotherapy plans is usually inaccurate because the similarity is compared only according to the image features of the medical images corresponding to the radiotherapy plans and the reference dimension and the reference information are less.
In view of the above problems, no effective solution has been proposed at present.
Disclosure of Invention
The application provides a method, a device, electronic equipment and a storage medium for determining the similarity of a radiotherapy plan, which at least solve the technical problem that the similarity determination of the radiotherapy plan is inaccurate due to the fact that the similarity of the radiotherapy plan is only compared according to image characteristics in the prior art.
According to an aspect of the present application, there is provided a method of similarity determination of radiotherapy plans, comprising: acquiring first characteristics corresponding to a first radiotherapy plan, wherein the first characteristics are used for representing distance information from each radioactive source in portal information formulated by the first radiotherapy plan to each first organ of N first organs, and the N first organs comprise a radiotherapy target area of a radiotherapy object corresponding to the first radiotherapy plan and at least one jeopardizing organ; acquiring second characteristics corresponding to a second radiotherapy plan, wherein the second characteristics are used for representing distance information from each radioactive source in portal information formulated by the second radiotherapy plan to each of M second organs, and the M second organs comprise a radiotherapy target zone and at least one jeopardizing organ of a radiotherapy object corresponding to the second radiotherapy plan; and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first characteristic and the second characteristic.
Optionally, the method for determining the similarity of the radiotherapy plan further comprises: acquiring third characteristics corresponding to the first radiotherapy plan, wherein the third characteristics are overlapped volume histogram information from each radioactive source to N first organs in the first radiotherapy plan; acquiring fourth characteristics corresponding to the second radiotherapy plan, wherein the fourth characteristics are overlapped volume histogram information of each radioactive source to M second organs in the second radiotherapy plan; and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first feature, the second feature, the third feature and the fourth feature.
Optionally, the method for determining the similarity of the radiotherapy plan further comprises: generating a first curve corresponding to the first radiotherapy plan according to the first characteristic and the third characteristic, wherein the first curve is a curve formed by taking the first characteristic as an abscissa and the third characteristic as an ordinate; generating a second curve corresponding to the second radiotherapy plan according to the second characteristic and the fourth characteristic, wherein the second curve is a curve formed by taking the second characteristic as an abscissa and the fourth characteristic as an ordinate; and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first curve and the second curve.
Optionally, the method for determining the similarity of the radiotherapy plan further comprises: displaying the first curve and the second curve on the same coordinate system, and calculating the area of a graph formed by the first curve and the second curve on the same coordinate system; and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the area of the graph, wherein the area of the graph and the similarity are in a negative correlation relationship.
Optionally, the method for determining the similarity of the radiotherapy plan further comprises: acquiring position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system, wherein the resampling coordinate system is used for enlarging the horizontal plane size on the basis of medical images in the first radiotherapy plan; and determining a first feature according to the position coordinates and the sketching information corresponding to the first radiotherapy plan, wherein the sketching information is used for representing outline information of each first organ in the N first organs in the medical image in the first radiotherapy plan.
Optionally, the method for determining the similarity of the radiotherapy plan further comprises: acquiring a corresponding field angle and a source wheelbase of each radioactive source in a first radiotherapy plan, wherein the corresponding source wheelbase of each radioactive source is used for representing the distance from the radioactive source to a rotating shaft of a rack; and determining the position coordinates of each radioactive source in the first radiotherapy plan in a resampling coordinate system according to the corresponding field angle and source wheelbase of each radioactive source in the first radiotherapy plan.
Optionally, the method for determining the similarity of the radiotherapy plan further comprises: acquiring position coordinates of each radiation source in a first radiotherapy plan on a first horizontal plane, wherein the first horizontal plane is a horizontal plane taking a radiotherapy target zone of a radiotherapy object corresponding to the first radiotherapy plan as a central point; and determining the position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system according to the position coordinates of each radiation source in the first radiotherapy plan on the first horizontal plane, the corresponding field angle of each radiation source in the first radiotherapy plan and the source wheelbase.
According to another aspect of the present application, there is also provided a similarity determination apparatus of a radiotherapy plan, including: the first acquisition unit is used for acquiring first characteristics corresponding to the first radiotherapy plan, wherein the first characteristics are used for representing distance information from each radioactive source in the portal information formulated by the first radiotherapy plan to each of N first organs, and the N first organs comprise a radiotherapy target area of a radiotherapy object corresponding to the first radiotherapy plan and at least one jeopardizing organ; the second acquisition unit is used for acquiring second characteristics corresponding to a second radiotherapy plan, wherein the second characteristics are used for representing distance information from each radioactive source in the portal information formulated by the second radiotherapy plan to each of M second organs, and the M second organs comprise a radiotherapy target area of a radiotherapy object corresponding to the second radiotherapy plan and at least one jeopardizing organ; and the determining unit is used for determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first characteristic and the second characteristic.
According to another aspect of the present application, there is also provided a computer readable storage medium, wherein the computer readable storage medium has a computer program stored therein, and wherein the computer program when executed controls a device in which the computer readable storage medium is located to perform the method for determining the similarity of radiotherapy plans according to any one of the above.
According to another aspect of the present application, there is also provided an electronic device, wherein the electronic device comprises one or more processors and a memory for storing one or more programs, wherein the one or more programs, when executed by the one or more processors, cause the one or more processors to implement the method of similarity determination of radiotherapy plans of any of the above.
In the application, the similarity of the radiotherapy plans is determined by comparing the distance information from the radioactive source to the radiotherapy target region and the organs at risk, first, the first characteristic corresponding to the first radiotherapy plan and the second characteristic corresponding to the second radiotherapy plan are obtained, and then, the similarity of the first radiotherapy plan and the second radiotherapy plan is determined according to the first characteristic and the second characteristic. The first features are used for representing distance information from each radiation source in the portal information formulated by the first radiotherapy plan to each first organ of N first organs, wherein the N first organs comprise a radiotherapy target zone of a radiotherapy object corresponding to the first radiotherapy plan and at least one jeopardizing organ; the second feature is used to characterize distance information of each radiation source in the portal information of the second radiation plan to each of M second organs including a target region of radiation of the radiation subject to which the second radiation plan corresponds and at least one organ at risk.
From the foregoing, unlike the prior art in which the similarity of the radiotherapy plan is determined only by the image features corresponding to the radiotherapy plan, the present application determines the similarity of the radiotherapy plan according to the distance information between the radiation source and the radiotherapy target and the organs at risk, and by contrast, the image features can generally only represent the sketched information of the radiotherapy target and the organs at risk, but cannot represent other information, and the distance information between the radiation source and the radiotherapy target and the organs at risk can represent both the radiation field information and the relative positional relationship among the radiation source, the radiotherapy target and the organs at risk, and at the same time, because the distance information between the radiation source and the radiotherapy target and the organs at risk of different shapes is different, the distance information between the radiation source and the radiotherapy target and the organs at risk can actually also represent the shape information of the radiotherapy target and the organs at risk.
Therefore, compared with the prior art, the technical scheme of the application can determine the similarity of the radiotherapy plan from more reference dimensions, thereby improving the accuracy of determining the similarity of the radiotherapy plan, and further solving the technical problem that the similarity determination of the radiotherapy plan is inaccurate due to the fact that the similarity of the radiotherapy plan is compared only according to image features in the prior art.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this specification, illustrate embodiments of the application and together with the description serve to explain the application and do not constitute a limitation on the application. In the drawings:
FIG. 1 is a flow chart of an alternative method of similarity determination of radiotherapy plans according to an embodiment of the application;
FIG. 2 is a schematic illustration of an alternative curve generated from distance information and overlapping volume histogram information in accordance with an embodiment of the present application;
FIG. 3 is a schematic illustration of a graph composed of an alternative first curve and second curve in accordance with an embodiment of the present application;
FIG. 4 is a flowchart of an alternative method of determining position coordinates of each radiation source in a first radiation treatment plan in a resampling coordinate system in accordance with an embodiment of the application;
FIG. 5 is an alternative distance profile according to an embodiment of the present application;
FIG. 6 is a schematic diagram of a process for determining the similarity of radiotherapy plans according to an embodiment of the application;
fig. 7 is a schematic diagram of an alternative radiotherapy plan similarity determination apparatus according to an embodiment of the present application.
Detailed Description
In order that those skilled in the art will better understand the present application, a technical solution in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in which it is apparent that the described embodiments are only some embodiments of the present application, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present application without making any inventive effort, shall fall within the scope of the present application.
It should be noted that the terms "first," "second," and the like in the description and the claims of the present application and the above figures are used for distinguishing between similar objects and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used may be interchanged where appropriate such that the embodiments of the application described herein may be implemented in sequences other than those illustrated or otherwise described herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.
It should be noted that, the relevant information (including but not limited to patient information and the like) and the data (including but not limited to data for presentation and analyzed data and the like) related to the present application are information and data authorized by the user or sufficiently authorized by each party. For example, an interface is provided between the system and the relevant user or institution, before acquiring the relevant information, the system needs to send an acquisition request to the user or institution through the interface, and acquire the relevant information after receiving the consent information fed back by the user or institution.
The application is further illustrated below in conjunction with the examples.
Example 1
According to an embodiment of the present application, there is provided an embodiment of a method of similarity determination of radiotherapy plans, it being noted that the steps shown in the flowcharts of the figures may be performed in a computer system such as a set of computer executable instructions, and although a logical order is shown in the flowcharts, in some cases the steps shown or described may be performed in an order different from that herein.
Fig. 1 is a flowchart of an alternative method of determining the similarity of radiotherapy plans, according to an embodiment of the application, as shown in fig. 1, the method comprising the steps of:
step S101, acquiring a first feature corresponding to the first radiotherapy plan.
In step S101, the first feature is used to characterize distance information from each radiation source in the portal information formulated by the first radiation plan to each of N first organs, including a target region of radiation of the radiation subject to which the first radiation plan corresponds and at least one organ at risk.
Optionally, the radiation field information formulated by the first radiation plan includes at least one radiation source, and it is assumed that the radiation field information formulated by the first radiation plan includes two radiation sources, namely a radiation source a and a radiation source B, a target area of radiation of the radiation object corresponding to the first radiation plan is a target area PTV1, and at least one endangered organ of the radiation object corresponding to the first radiation plan is OAR1 and OAR2. On the basis of this, the first features corresponding to the first radiotherapy plan are used to characterize the distance information of the radiation source a to the target volumes PTV1, OAR2, respectively, and the distance information of the radiation source B to the target volumes PTV1, OAR2, respectively.
Step S102, obtaining a second characteristic corresponding to a second radiotherapy plan.
In step S102, the second feature is used to characterize distance information of each radiation source in the portal information formulated by the second radiation plan to each of M second organs including a target area of radiation of the radiation subject to which the second radiation plan corresponds and at least one organ at risk.
Alternatively, the radiotherapy object corresponding to the first radiotherapy plan and the radiotherapy object corresponding to the second radiotherapy plan may be the same object or may be different objects. In addition, the field information formulated by the second radiotherapy plan includes at least one radiation source, for example, it is assumed that the field information formulated by the second radiotherapy plan also includes two radiation sources, namely, radiation source C and radiation source D, respectively, a target region PTV2 of a radiotherapy target region of a radiotherapy object corresponding to the second radiotherapy plan, and OAR3 and OAR4 of at least one organs at risk of the radiotherapy object corresponding to the second radiotherapy plan, respectively. On the basis of this, a second feature corresponding to the second radiotherapy plan is used to characterize the distance information of the radiation source C to the target volumes PTV2, OAR3, OAR4, respectively, and the distance information of the radiation source D to the target volumes PTV2, OAR3, OAR4, respectively.
Step S103, determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first characteristic and the second characteristic.
Optionally, since the first feature and the second feature are both distance information characterizing the radiation source to the radiotherapy target zone and the organ at risk, comparing the similarity of the first feature and the second feature is comparing the similarity of the distance information of the respective radiation source to the radiotherapy target zone and the organ at risk in the first radiotherapy plan and the second radiotherapy plan, and if the similarity of the first feature and the second feature is higher, it is indicated that the similarity of the first radiotherapy plan and the second radiotherapy plan is higher.
Based on the above-mentioned contents of step S101 to step S103, in the present application, the similarity of the radiotherapy plan is determined by comparing the distance information from the radiation source to the radiotherapy target region and the organs at risk, first, the first feature corresponding to the first radiotherapy plan and the second feature corresponding to the second radiotherapy plan are obtained, and then, the similarity of the first radiotherapy plan and the second radiotherapy plan is determined according to the first feature and the second feature. The first features are used for representing distance information from each radiation source in the portal information formulated by the first radiotherapy plan to each first organ of N first organs, wherein the N first organs comprise a radiotherapy target zone of a radiotherapy object corresponding to the first radiotherapy plan and at least one jeopardizing organ; the second feature is used to characterize distance information of each radiation source in the portal information of the second radiation plan to each of M second organs including a target region of radiation of the radiation subject to which the second radiation plan corresponds and at least one organ at risk.
According to the method, the similarity of the radiotherapy plan is determined according to the distance information from the radioactive source to the radiotherapy target area and the jeopardizing organ, as the image characteristics can only represent the sketching information of the radiotherapy target area and the jeopardizing organ, other information cannot be represented, the distance information from the radioactive source to the radiotherapy target area and the jeopardizing organ can represent the radiation field information, the relative position relation among the radioactive source, the radiotherapy target area and the jeopardizing organ can also be represented, and in addition, the distance information from the radioactive source to the radiotherapy target area and the jeopardizing organ with different shapes can also be different according to the distance information from the radioactive source to the radiotherapy target area and the jeopardizing organ, so that compared with the prior art, the method can determine the similarity of the radiotherapy plan from more reference dimensions, and further the accuracy of the similarity determination of the radiotherapy plan is improved, and the problem of the similarity determination of the radiotherapy plan caused by the fact that the radiotherapy plan is only compared according to the image characteristics in the prior art is solved.
In an alternative embodiment, a device for determining similarity of radiotherapy plans may be used as an execution body of the method for determining similarity of radiotherapy plans in the embodiment of the present application, where the device for determining similarity of radiotherapy plans may be a software system or an embedded system combining software and hardware.
In an alternative embodiment, the similarity determining device of the radiotherapy plan may obtain a third feature corresponding to the first radiotherapy plan and obtain a fourth feature corresponding to the second radiotherapy plan, where the third feature is overlapping volume histogram information of each radiation source to N first organs in the first radiotherapy plan, and the fourth feature is overlapping volume histogram information of each radiation source to M second organs in the second radiotherapy plan. Finally, the similarity determination device of the radiotherapy plans determines the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first feature, the second feature, the third feature and the fourth feature.
Alternatively, the overlapping volume histogram information of each radiation source to the N first organs in the first radiation therapy plan may be distance statistics of each radiation source with respect to the N first organs, wherein the distance statistics include intersection distance information of all distance information corresponding to the N first organs. In addition, the overlapping volume histogram information of each radiation source to N first organs in the first radiation plan may further include spatial associations between any two first organs, including, but not limited to, spatial associations between each organ at risk of a radiation subject corresponding to the first radiation plan and a target region of radiation, and spatial associations between different organs at risk of a radiation subject corresponding to the first radiation plan.
Correspondingly, the overlapping volume histogram information of each radiation source to the M second organs in the second radiation treatment plan may be distance statistics of each radiation source with respect to the M second organs, where the distance statistics include intersection distance information of all distance information corresponding to the M second organs. In addition, the overlapping volume histogram information of each radiation source to M second organs in the second radiation plan may further include spatial associations between any two second organs, including, but not limited to, spatial associations between each organ at risk of a radiation subject corresponding to the second radiation plan and a target region of radiation, and spatial associations between different organs at risk of a radiation subject corresponding to the second radiation plan.
In an alternative embodiment, the similarity determining device of the radiotherapy plan may generate a first curve corresponding to the first radiotherapy plan according to the first feature and the third feature, and generate a second curve corresponding to the second radiotherapy plan according to the second feature and the fourth feature, where the first curve is a curve formed by taking the first feature as an abscissa and the third feature as an ordinate, and the second curve is a curve formed by taking the second feature as an abscissa and the fourth feature as an ordinate. Finally, the similarity determination device of the radiotherapy plans determines the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first curve and the second curve.
Optionally, fig. 2 is a schematic diagram of an alternative curve generated according to the distance information and the overlapping volume histogram information, and as shown in fig. 2, the abscissa corresponding to the curve characterizes the distance information, e.g., r1, r2, d, of the radiation source to the radiotherapy target zone or the organ at risk, according to an embodiment of the present application. The ordinate corresponding to the curve characterizes overlapping volume histogram information of the radiation sources to the target radiotherapy region or the organ at risk, i.e. statistical information of the distance of each radiation source relative to the target radiotherapy region or the organ at risk.
It should be noted that the curve in fig. 2 is only an example, and is used to schematically illustrate one expression form of the first curve and/or the second curve, so the curve in fig. 2 may refer to both the first curve and the second curve, and the corresponding abscissa and ordinate may be adaptively changed according to the actual situation.
In an alternative embodiment, the similarity determining device of the radiotherapy plan may display the first curve and the second curve on the same coordinate system, calculate an area of a graph formed by the first curve and the second curve on the same coordinate system, and then determine the similarity of the first radiotherapy plan and the second radiotherapy plan according to the area of the graph, where the area of the graph and the similarity are in a negative correlation.
Alternatively, FIG. 3 is a schematic illustration of a graph composed of an alternative first curve and second curve in accordance with an embodiment of the present application. It will be readily appreciated that if the first curve and the second curve are identical, the two curves will overlap completely in the same coordinate system, and if the similarity between the first curve and the second curve is high, the area of the graph formed by the two curves will be small. On the basis, the similarity of the first radiotherapy plan and the second radiotherapy plan can be determined according to the areas of the patterns by displaying the first curve and the second curve on the same coordinate system and calculating the areas of the patterns formed by the first curve and the second curve on the same coordinate system.
In an alternative embodiment, in order to obtain the first features corresponding to the first radiation plan, the similarity determination means of the radiation plan first obtains position coordinates of each radiation source in the first radiation plan in a resampling coordinate system, wherein the resampling coordinate system is used for enlarging the horizontal plane size on the basis of the medical image in the first radiation plan. Then, the similarity determining device of the radiotherapy plan determines the first feature according to the position coordinates and sketching information corresponding to the first radiotherapy plan, wherein the sketching information is used for representing outline information of each first organ of the N first organs in a medical image of the first radiotherapy plan.
Optionally, by expanding the horizontal plane size based on the medical image in the first radiotherapy plan by resampling the coordinate system, it may be ensured that the position coordinates of each radiation source in the first radiotherapy plan can be accurately acquired, so as to avoid the problem that the position coordinates of some radiation sources cannot be directly determined due to undersize of the horizontal plane corresponding to the medical image.
In an alternative embodiment, fig. 4 is an alternative flow chart for determining the position coordinates of each radiation source in the first radiation treatment plan in the resampling coordinate system, as shown in fig. 4, comprising the steps of:
in step S401, a source wheelbase and a field angle corresponding to each radiation source in the first radiotherapy plan are obtained, where the source wheelbase corresponding to each radiation source is used to characterize a distance from the radiation source to a gantry rotation axis.
Alternatively, the field angle may be denoted as θ and the source wheelbase may be denoted as D SAD 。
Step S402, determining the position coordinates of each radioactive source in the first radiotherapy plan in a resampling coordinate system according to the corresponding radiation field angle and source wheelbase of each radioactive source in the first radiotherapy plan.
Optionally, in step S402, the similarity determining device of the radiotherapy plan first acquires a position coordinate of each radiation source in the first radiotherapy plan on a first horizontal plane, where the first horizontal plane is a horizontal plane with a radiotherapy target zone of a radiotherapy object corresponding to the first radiotherapy plan as a center point. Then, the similarity determining device of the radiotherapy plans determines the position coordinates of each radioactive source in the first radiotherapy plan in the resampling coordinate system according to the position coordinates of each radioactive source in the first radiotherapy plan on the first horizontal plane, the corresponding radiation field angle of each radioactive source in the first radiotherapy plan and the source wheelbase.
Alternatively, the position coordinates of the radiation source on the first horizontal plane may be expressed as (X P ，Y P ) In resampling coordinates of the sourceThe position coordinates can be expressed as (X) S ，Y S )。
Wherein formula (1) shows X S Is a calculation formula of (2).
X S ＝X P +D SAD *sinθ (1)
Equation (2) shows Y S Is a calculation formula of (2).
Y S ＝Y P +D SAD *cosθ (2)
In an alternative embodiment, after obtaining the position coordinates of the radiation source in the resampling coordinate system, the distance information (i.e. the first feature) between the radiation source and the radiotherapy target region and the at least one organ at risk of the radiotherapy object corresponding to the first radiotherapy plan is further determined by combining the sketching information corresponding to the first radiotherapy plan, and the specific operation can be seen in the following formula (3).
M ROI ＝DistMap(P P )*C ROI (3)
Wherein in formula (3), P P ＝(X P ，Y P ) DistMap is a function for generating an entire distance profile around a radiation source, M ROI Characterizing a corresponding first feature of the radiation source (the first feature may be expressed as a complete distance profile around the radiation source), C ROI And characterizing sketching information corresponding to the first radiotherapy plan.
Optionally, fig. 5 is an optional distance distribution diagram according to an embodiment of the present application, where as shown in fig. 5, the PTV in fig. 5 is a sketched image corresponding to the radiotherapy target region (i.e., sketched information corresponding to the radiotherapy target region), the OAR1 in fig. 5 is a sketched image corresponding to the organ-at-risk 1, and the OAR2 in fig. 5 is a sketched image corresponding to the organ-at-risk 2. Furthermore, the arrows connecting the radiation source with the PTV, OAR1 and OAR2 in FIG. 5 are shown as distance information between the radiation source and the PTV, OAR1 and OAR 2.
It should be noted that fig. 5 may be converted to generate fig. 2, where fig. 2 is a statistic form of fig. 5, that is, fig. 2 may further represent overlapping volume histogram information of the radiation source to the organ at risk and the radiotherapy target zone based on fig. 5.
In an alternative embodiment, in order to obtain the second feature corresponding to the second radiotherapy plan, the similarity determining device of the radiotherapy plan may obtain a position coordinate of each radiation source in the second radiotherapy plan in the resampling coordinate system, and determine the second feature according to the position coordinate and delineating information corresponding to the second radiotherapy plan, where the delineating information is used to characterize contour information of each of the M second organs in a medical image in the second radiotherapy plan.
Wherein acquiring the position coordinates of each radiation source in the second radiation therapy plan in the resampling coordinate system comprises: and acquiring a corresponding field angle and a source wheelbase of each radiation source in the second radiotherapy plan, and determining the position coordinates of each radiation source in the second radiotherapy plan in a resampling coordinate system according to the corresponding field angle and the source wheelbase of each radiation source in the second radiotherapy plan.
Optionally, determining the position coordinates of each radiation source in the second radiotherapy plan in the resampling coordinate system according to the corresponding field angle and source wheelbase of each radiation source in the second radiotherapy plan includes: and acquiring the position coordinates of each radiation source in the second radiotherapy plan on the second horizontal plane, and determining the position coordinates of each radiation source in the second radiotherapy plan in a resampling coordinate system according to the position coordinates of each radiation source in the second radiotherapy plan on the second horizontal plane, the corresponding field angle of each radiation source in the second radiotherapy plan and the source wheelbase. The second horizontal plane is a horizontal plane taking a radiotherapy target zone of a radiotherapy object corresponding to the second radiotherapy plan as a central point.
In an alternative embodiment, fig. 6 is a schematic diagram of a process for determining similarity of radiotherapy plans according to an embodiment of the application, as shown in fig. 6, first a first curve corresponding to a first radiotherapy plan and a second curve corresponding to a second radiotherapy plan are generated respectively, and then the similarity of the first radiotherapy plan and the second radiotherapy plan is determined by an area of a graph formed by the first curve and the second curve. Fig. 6 also shows a specific procedure of generating the first curve/second curve, where the field information of the radiotherapy plan (first radiotherapy plan or second radiotherapy plan) is first read, where the field information includes the field number and the field angle. Then, position coordinates of the radiation source are determined on a resampling coordinate system, a distance distribution map of the radiation source to the ROI (the endangered organ and/or the radiotherapy target zone) is determined according to the position coordinates, and the first curve/the second curve can be obtained by converting the distance distribution map into a statistic form.
From the above, unlike the prior art in which the similarity of the radiotherapy plan is determined only by the image features corresponding to the radiotherapy plan, the method determines the similarity of the radiotherapy plan according to the distance information between the radioactive source and the radiotherapy target and the organs at risk, and by contrast, the image features can generally only represent the sketching information of the radiotherapy target and the organs at risk, but cannot represent other information, and the distance information between the radioactive source and the radiotherapy target and the organs at risk can represent both the radiation field information and the relative positional relationship among the radioactive source, the radiotherapy target and the organs at risk, and meanwhile, because the distance information between the radioactive source and the radiotherapy target and the organs at risk corresponding to the radioactive source with different shapes is also different, the distance information between the radioactive source and the radiotherapy target and the organs at risk can actually represent the shape information of the radiotherapy target and the organs at risk.
Therefore, compared with the prior art, the technical scheme of the application can determine the similarity of the radiotherapy plan from more reference dimensions, thereby improving the accuracy of determining the similarity of the radiotherapy plan, and further solving the technical problem that the similarity determination of the radiotherapy plan is inaccurate due to the fact that the similarity of the radiotherapy plan is compared only according to image features in the prior art.
Example 2
According to an embodiment of the present application, an embodiment of a similarity determination device for radiotherapy planning is provided. Fig. 7 is a schematic diagram of an alternative radiotherapy plan similarity determining apparatus according to an embodiment of the present application, as shown in fig. 7, the radiotherapy plan similarity determining apparatus includes: a first acquisition unit 701, a second acquisition unit 702, and a determination unit 703.
Optionally, the first obtaining unit 701 is configured to obtain first features corresponding to a first radiotherapy plan, where the first features are used to characterize distance information from each radiation source in the portal information formulated by the first radiotherapy plan to each of N first organs, where the N first organs include a radiotherapy target region of a radiotherapy object corresponding to the first radiotherapy plan and at least one jeopardizing organ; a second obtaining unit 702, configured to obtain a second feature corresponding to a second radiotherapy plan, where the second feature is used to characterize distance information from each radiation source in the portal information formulated by the second radiotherapy plan to each of M second organs, and the M second organs include a radiotherapy target region of a radiotherapy object corresponding to the second radiotherapy plan and at least one jeopardizing organ; a determining unit 703 for determining a similarity of the first radiation therapy plan and the second radiation therapy plan based on the first feature and the second feature.
Optionally, the determining unit 703 includes: the device comprises a first acquisition subunit, a second acquisition subunit and a first determination subunit. The first acquisition subunit is used for acquiring third characteristics corresponding to the first radiotherapy plan, wherein the third characteristics are overlapped volume histogram information from each radioactive source to N first organs in the first radiotherapy plan; a second obtaining subunit, configured to obtain a fourth feature corresponding to the second radiotherapy plan, where the fourth feature is overlapping volume histogram information of each radiation source in the second radiotherapy plan to M second organs; and the first determination subunit is used for determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first feature, the second feature, the third feature and the fourth feature.
Optionally, the first determining subunit includes: the device comprises a first generation module, a second generation module and a first determination module. The first generation module is used for generating a first curve corresponding to the first radiotherapy plan according to the first characteristic and the third characteristic, wherein the first curve is a curve formed by taking the first characteristic as an abscissa and taking the third characteristic as an ordinate; the second generation module is used for generating a second curve corresponding to a second radiotherapy plan according to the second characteristic and the fourth characteristic, wherein the second curve is a curve formed by taking the second characteristic as an abscissa and the fourth characteristic as an ordinate; and the first determining module is used for determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first curve and the second curve.
Optionally, the first determining module includes: the computing sub-module and the first determining sub-module. The calculating submodule is used for displaying the first curve and the second curve on the same coordinate system and calculating the area of a graph formed by the first curve and the second curve on the same coordinate system; and the first determining submodule is used for determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the area of the graph, wherein the area of the graph and the similarity are in a negative correlation relationship.
Optionally, the first acquisition unit 701 includes: a third acquisition subunit and a second determination subunit. The third acquisition subunit is used for acquiring the position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system, wherein the resampling coordinate system is used for enlarging the horizontal plane size on the basis of the medical image in the first radiotherapy plan; and the second determining subunit is used for determining the first characteristic according to the position coordinates and the sketching information corresponding to the first radiotherapy plan, wherein the sketching information is used for representing the outline information of each first organ of the N first organs in the medical image in the first radiotherapy plan.
Optionally, the third acquisition subunit includes: the device comprises a first acquisition module and a second determination module. The first acquisition module is used for acquiring a field angle and a source wheelbase corresponding to each radioactive source in the first radiotherapy plan, wherein the source wheelbase corresponding to each radioactive source is used for representing the distance from the radioactive source to a rotating shaft of the rack; and the second determining module is used for determining the position coordinates of each radioactive source in the first radiotherapy plan in the resampling coordinate system according to the corresponding radiation field angle and source wheelbase of each radioactive source in the first radiotherapy plan.
Optionally, the second determining module includes: the first acquisition sub-module and the second determination sub-module. The first acquisition submodule is used for acquiring the position coordinates of each radiation source in the first radiotherapy plan on a first horizontal plane, wherein the first horizontal plane is a horizontal plane taking a radiotherapy target area of a radiotherapy object corresponding to the first radiotherapy plan as a central point; and the second determining submodule is used for determining the position coordinate of each radiation source in the first radiation therapy plan in the resampling coordinate system according to the position coordinate of each radiation source in the first radiation therapy plan on the first horizontal plane, the corresponding radiation field angle of each radiation source in the first radiation therapy plan and the source wheelbase.
Example 3
According to another aspect of the embodiments of the present application, there is also provided a computer readable storage medium, the computer readable storage medium including a stored computer program, wherein the computer program when run controls a device in which the computer readable storage medium is located to perform the method for determining the similarity of radiotherapy plans according to any one of the above embodiments 1.
Example 4
According to another aspect of the embodiment of the present application, there is also provided an electronic device, including: a processor; and a memory for storing executable instructions of the processor; wherein the processor is configured to perform the similarity determination method of the radiotherapy plan of any of the above-described embodiments 1 via execution of the executable instructions.
The foregoing embodiment numbers of the present application are merely for the purpose of description, and do not represent the advantages or disadvantages of the embodiments.
In the foregoing embodiments of the present application, the descriptions of the embodiments are emphasized, and for a portion of this disclosure that is not described in detail in this embodiment, reference is made to the related descriptions of other embodiments.
In the several embodiments provided in the present application, it should be understood that the disclosed technology may be implemented in other manners. The above-described embodiments of the apparatus are merely exemplary, and the division of units may be a logic function division, and there may be another division manner in actual implementation, for example, multiple units or components may be combined or integrated into another system, or some features may be omitted, or not performed. Alternatively, the coupling or direct coupling or communication connection shown or discussed with each other may be through some interfaces, units or modules, or may be in electrical or other forms.
The units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed over a plurality of units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.
In addition, each functional unit in the embodiments of the present application may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit. The integrated units may be implemented in hardware or in software functional units.
The integrated units, if implemented in the form of software functional units and sold or used as stand-alone products, may be stored in a computer readable storage medium. Based on such understanding, the technical solution of the present application may be embodied in essence or a part contributing to the prior art or all or part of the technical solution in the form of a software product stored in a storage medium, comprising several instructions for causing a computer device (which may be a personal computer, a server or a network device, etc.) to perform all or part of the steps of the method of the various embodiments of the present application. And the aforementioned storage medium includes: a U-disk, a Read-Only Memory (ROM), a random access Memory (RAM, random Access Memory), a removable hard disk, a magnetic disk, or an optical disk, or other various media capable of storing program codes.
The foregoing is merely a preferred embodiment of the present application and it should be noted that modifications and adaptations to those skilled in the art may be made without departing from the principles of the present application, which are intended to be comprehended within the scope of the present application.

Claims (10)

1. A method for determining similarity of radiation therapy plans, comprising:
acquiring first characteristics corresponding to a first radiotherapy plan, wherein the first characteristics are used for representing distance information from each radioactive source to each first organ of N first organs in portal information formulated by the first radiotherapy plan, and the N first organs comprise a radiotherapy target area and at least one jeopardizing organ of a radiotherapy object corresponding to the first radiotherapy plan;
acquiring second characteristics corresponding to a second radiotherapy plan, wherein the second characteristics are used for representing distance information from each radioactive source to each of M second organs in portal information formulated by the second radiotherapy plan, and the M second organs comprise a radiotherapy target region and at least one jeopardizing organ of a radiotherapy object corresponding to the second radiotherapy plan;
and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first characteristic and the second characteristic.
2. The method of similarity determination of radiation therapy plans according to claim 1, characterized in that determining the similarity of the first radiation therapy plan and the second radiation therapy plan from the first feature and the second feature comprises:
acquiring a third feature corresponding to the first radiotherapy plan, wherein the third feature is overlapping volume histogram information of each radiation source in the first radiotherapy plan to the N first organs;
acquiring fourth characteristics corresponding to the second radiotherapy plan, wherein the fourth characteristics are overlapping volume histogram information of each radiation source in the second radiotherapy plan to the M second organs;
and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first feature, the second feature, the third feature and the fourth feature.
3. The method of determining a similarity of a radiation therapy plan according to claim 2, wherein determining the similarity of the first radiation therapy plan and the second radiation therapy plan based on the first feature, the second feature, the third feature, and the fourth feature comprises:
generating a first curve corresponding to the first radiotherapy plan according to the first feature and the third feature, wherein the first curve is a curve formed by taking the first feature as an abscissa and the third feature as an ordinate;
Generating a second curve corresponding to the second radiotherapy plan according to the second characteristic and the fourth characteristic, wherein the second curve is a curve formed by taking the second characteristic as an abscissa and the fourth characteristic as an ordinate;
and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first curve and the second curve.
4. The method of determining the similarity of radiation therapy plans according to claim 3, wherein determining the similarity of the first radiation therapy plan and the second radiation therapy plan from the first curve and the second curve comprises:
displaying the first curve and the second curve on the same coordinate system, and calculating the area of a graph formed by the first curve and the second curve on the same coordinate system;
and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the area of the graph, wherein the area of the graph and the similarity are in a negative correlation relationship.
5. The method for determining the similarity of radiation therapy plans according to claim 1, wherein acquiring the first feature corresponding to the first radiation therapy plan comprises:
Acquiring position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system, wherein the resampling coordinate system is used for enlarging the horizontal plane size on the basis of medical images in the first radiotherapy plan;
and determining the first characteristic according to the position coordinates and the sketching information corresponding to the first radiotherapy plan, wherein the sketching information is used for representing outline information of each first organ of the N first organs in medical images in the first radiotherapy plan.
6. The method of similarity determination of radiation therapy plans according to claim 5, wherein obtaining position coordinates of each radiation source in the first radiation therapy plan in a resampling coordinate system comprises:
acquiring a corresponding field angle and a source wheelbase of each radioactive source in the first radiotherapy plan, wherein the corresponding source wheelbase of each radioactive source is used for representing the distance from the radioactive source to a rotating shaft of a rack;
and determining the position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system according to the corresponding radiation field angle and source wheelbase of each radiation source in the first radiotherapy plan.
7. The method of similarity determination of radiation therapy plans according to claim 6, wherein determining the position coordinates of each radiation source in the first radiation therapy plan in a resampling coordinate system according to the corresponding field angle and source wheelbase of each radiation source in the first radiation therapy plan comprises:
Acquiring position coordinates of each radiation source in the first radiotherapy plan on a first horizontal plane, wherein the first horizontal plane is a horizontal plane taking a radiotherapy target zone of a radiotherapy object corresponding to the first radiotherapy plan as a central point;
and determining the position coordinates of each radiation source in the first radiation therapy plan in a resampling coordinate system according to the position coordinates of each radiation source in the first radiation therapy plan on the first horizontal plane, the corresponding radiation field angle of each radiation source in the first radiation therapy plan and the source wheelbase.
8. A similarity determination apparatus for a radiation therapy plan, comprising:
a first obtaining unit, configured to obtain a first feature corresponding to a first radiotherapy plan, where the first feature is used to characterize distance information from each radiation source to each first organ of N first organs in portal information formulated by the first radiotherapy plan, where the N first organs include a radiotherapy target region of a radiotherapy object corresponding to the first radiotherapy plan and at least one jeopardizing organ;
a second obtaining unit, configured to obtain a second feature corresponding to a second radiotherapy plan, where the second feature is used to characterize distance information from each radiation source to each of M second organs in portal information formulated by the second radiotherapy plan, where the M second organs include a radiotherapy target region of a radiotherapy object corresponding to the second radiotherapy plan and at least one jeopardizing organ;
And the determining unit is used for determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first characteristic and the second characteristic.
9. A computer readable storage medium, wherein a computer program is stored in the computer readable storage medium, and wherein the computer program when run controls a device in which the computer readable storage medium is located to perform the method of similarity determination of radiotherapy plans according to any one of claims 1 to 7.
10. An electronic device comprising one or more processors and a memory for storing one or more programs, wherein the one or more programs, when executed by the one or more processors, cause the one or more processors to implement the method of similarity determination of radiotherapy plans of any one of claims 1 to 7.
CN202311175065.5A 2023-09-12 2023-09-12 Similarity determination method and device for radiotherapy plan, electronic equipment and storage medium Pending CN117194999A (en)

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