CN117106549A - Chronic leukemia lymphocyte separation and extraction device - Google Patents

Chronic leukemia lymphocyte separation and extraction device Download PDF

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Publication number
CN117106549A
CN117106549A CN202311082698.1A CN202311082698A CN117106549A CN 117106549 A CN117106549 A CN 117106549A CN 202311082698 A CN202311082698 A CN 202311082698A CN 117106549 A CN117106549 A CN 117106549A
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extraction
cabinet
placing
support
square
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李晶
彭昳
赵小明
于姗姗
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Jilin University
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Jilin University
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/48Holding appliances; Racks; Supports
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/52Mobile; Means for transporting the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/05Means for pre-treatment of biological substances by centrifugation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention provides a chronic leukemia lymphocyte separation and extraction device, which comprises a placement mechanism, wherein the placement mechanism comprises a bearing base placed on the ground, a square bearing bottom plate is placed in the middle of the top surface of the bearing base, a trapezoid bearing plate is arranged in the middle of the top end of the square bearing bottom plate, a round sleeve is arranged on the side of the top surface of the trapezoid bearing plate, a linkage cylinder is vertically arranged in the middle of the top end of the round sleeve, a trapezoid frame is supported in the middle of the top end of a cylinder body of the linkage cylinder, a square placement plate is fixedly placed in the middle of the top end of the trapezoid frame, a connecting bearing plate for supporting is transversely arranged in the middle of the top end of the plate surface of the square placement plate, and in operation, the positions of the square bearing bottom plate and the round sleeve at the upper end are communicated through the bearing base, so that one end of the cylinder body of the linkage cylinder is finely adjusted to realize telescopic placement, and a user can place according to the top end of the frame of the trapezoid frame.

Description

Chronic leukemia lymphocyte separation and extraction device
Technical Field
The invention belongs to the technical field of medical treatment, and particularly relates to a chronic leukemia lymphocyte separation and extraction device.
Background
Chronic lymphocytic leukemia is a malignant tumor that is primarily derived from hematopoietic tissues. The tumor cells are monoclonal B lymphocytes, and the morphology is similar to that of small normal mature lymphocytes, and accumulate in blood, bone marrow and lymphoid tissues.
The Chinese patent application with the patent application number of 2021222455368 discloses a chronic leukemia lymphocyte separation and extraction device, which relates to the technical field of cell separation and comprises a device main body, a control panel, a top cover and a first hinge, wherein a hydraulic rod is arranged at the joint of the device main body and the top cover, a buffer structure is arranged at the rear end of the device main body, a separation groove is formed in the outer surface of the upper end of the device main body, a separation plate is arranged in the separation groove, and an overhaul structure is arranged at the outer side of the device main body; in the placing process of the device main body, the device main body can be placed according to different flatness of the wall body, so that the device main body is attached to the wall body, the stability of the device main body is improved, meanwhile, the friction between the wall body and the device main body is reduced, in addition, an access door is closed and opened through an access structure, the device main body is convenient to quickly overhaul, the disassembly of bolts is avoided, and the overhaul efficiency of the device is improved;
1) The traditional chronic leukemia lymphocytes can not extract and analyze samples stored in test tubes of a large number of patients in terms of extraction, and the manual extraction efficiency is too low, so that the time for a patient to check out an inspection reporting party is prolonged, in addition, when personnel analyze the samples extracted in a classified way in the later period, no specific analysis and refrigeration equipment is provided, the results which are difficult to recover in terms of storage in the present period are easily caused, and the deterioration or activity reduction of the sample lymphocytes is easily caused;
2) The traditional lymphocyte separation and extraction seriously affects the analysis and detection efficiency of the post-lymphocyte in the aspect of sample treatment of chronic leukemia lymph in the later stage, and the test tube stacking and arrangement is complicated in the later stage when the sample is extracted, so that the later stage stacking analysis reduces the efficiency.
Disclosure of Invention
The invention aims to provide a chronic leukemia lymphocyte separation and extraction device, which aims to solve the technical problems.
In order to achieve the above purpose, the present invention provides the following technical solutions: the utility model provides a chronic leukemia lymphocyte separation extraction element, includes a placement machine constructs, placement machine constructs including placing in a bearing base on ground, and wherein this bearing base's top surface middle part has placed a square bearing bottom plate, square bearing bottom plate's top middle part is equipped with trapezoidal loading board, a circular sleeve has been seted up to trapezoidal bearing plate's top surface avris, circular telescopic top middle part is vertical installs a linkage pneumatic cylinder, the cylinder body top middle part of linkage pneumatic cylinder supports a ladder frame, the fixed square board of placing in top middle part of ladder frame, wherein the board top middle part of this square board of placing transversely is equipped with a connection loading board that is used for supporting, the top mid-mounting of connection loading board has a square bearing base that is used for magnetism absorption, and wherein the round slot that is used for placing side by side has been placed to the top middle part of this square bearing bottom plate, and wherein this round slotted mid-mounting plate has a mounting panel, a plurality of independent outer frames have been laid in proper order to the trench middle part, and its top mid-mounting is vertical has a conveyer pipe, the pole setting middle part of conveyer pipe is vertical installs a connection, the top pole setting top of connecting is equipped with the body of rod frame.
As a preferred embodiment of the present invention: the rear end of the trapezoid bearing plate is provided with an extraction mechanism for medical extraction;
the extraction mechanism further comprises a vertical placing cabinet placed in the vertical placing cabinet, wherein a first placing support is arranged in the middle of the cabinet body of the vertical placing cabinet, a sliding groove is linearly formed in the middle of the top end of the first placing support in a sliding mode, a turntable base used for driving to rotate is attached to the middle of the groove of the sliding groove, a driving turntable is arranged in the middle of the top end of the turntable base, a transmission sleeve is vertically arranged at the top of the disc face of the driving turntable, an angle limiter is arranged at the rear end of the transmission sleeve, a rotating disc is arranged in the middle of the top end of the angle limiter, a rotating shaft is arranged in the middle of the top end of the rotating disc, a turnover large arm is arranged at one end of the rotating shaft, an electric rolling shaft is connected to the middle of the turnover large arm in a transmission mode, and a stirring supporting rod is arranged at one end of the electric rolling shaft.
As a preferred embodiment of the present invention: the middle part of the top of stirring the vaulting pole is equipped with a swing forearm, the middle part of swing forearm is equipped with the drive roller bearing, the middle part linkage of drive roller bearing is equipped with drives rotatory forearm driving motor, forearm driving motor's output and the one end linkage setting of drive roller bearing, the one end of drive roller bearing is equipped with the linkage sleeve pipe, the one end of linkage sleeve pipe is equipped with the arc regulation support that is used for injecting.
As a preferred embodiment of the present invention: the utility model provides a draw-out mechanism is installed to arc regulation support's top mid-mounting, draw-out mechanism is including installing the several style of calligraphy support that sets up in arc regulation support bottom, the vertical extraction frame of establishing on the arc connecting surface in top middle part of several style of calligraphy support, the bottom of extracting the frame is equipped with the flexible jar of lift, the cylinder body bottom of the flexible jar of lift is equipped with a pneumatic extraction support that is used for the tractive, the middle part of pneumatic extraction support is equipped with a plurality of independent pneumatic valve in proper order, the valve body bottom of pneumatic valve is equipped with the L type of being used for drawing and connects the siphunculus, the bottom middle part cover of L type switch-on hose is equipped with a detection valve table that is used for sealed UNICOM, the bottom mid-mounting of detection valve table has a connector, the bottom middle part of connector is corresponding side by side with the conveyer pipe mouth of pipe of lower extreme.
As a preferred embodiment of the present invention: the device is characterized in that an arch-shaped holding frame is hinged to the middle of the top end of the U-shaped support, a hinged connecting rod is obliquely arranged on the side of the bottom of the arch-shaped holding frame, the bottom end of the hinged connecting rod moves downwards with a pneumatic drawing support at the lower end, a classification and extraction mechanism is arranged on the side of the bottom of the vertical holding cabinet, the classification and extraction mechanism comprises an assay drawing support arranged on the side wall of the hinged connecting rod, a U-shaped clamping frame used for clamping is arranged on the front surface of the assay drawing support, and an arc-shaped stirring support is vertically arranged on the middle of the top end of the U-shaped clamping frame.
As a preferred embodiment of the present invention: the middle part of the arc toggle support is provided with an extraction frame, the middle part of the top end of the extraction frame is provided with a concave groove, the middle part of the groove of the concave groove is provided with an extraction sleeve, the middle part of the top end of the extraction sleeve is provided with an extraction piston, and the middle part of the top end of the extraction piston is provided with a telescopic connecting rod.
The telescopic connecting rod comprises a telescopic connecting rod body, and is characterized in that a connecting stay bar is vertically arranged at the bottom of the telescopic connecting rod body, a connecting needle head is arranged at one end of the connecting stay bar, a square bearing plate is arranged at the bottom of the connecting needle head, a bearing support used for clamping is arranged in the middle of the bottom end of the square bearing plate, and a trapezoid control mechanism is arranged at the middle of the bottom end of the connecting stay bar.
As a preferred embodiment of the present invention: the bottom middle part of trapezoidal control mechanism is equipped with a trapezoidal cabinet of placing, the inside cavity of one end cabinet body of cabinet is placed to trapezoidal, wherein is located the cabinet body upper end of cabinet is placed to trapezoidal installs a second and places the support, the top mid-mounting of support is placed to the second has one to place the base, the top middle part of placing the base is equipped with one and is used for supporting and places the bottom plate, the top middle part of placing the bottom plate is equipped with one and is used for placing the base.
As a preferred embodiment of the present invention: the novel energy-saving vacuum cabinet is characterized in that a trapezoid placing cabinet is arranged on the side of the placing base, a control cabinet used for being connected is arranged at one end of the trapezoid cabinet, a connecting side plate is transversely arranged in the middle of the top end of the control cabinet, a control box is arranged in the middle of the top end of the connecting side plate, a vacuum motor used for driving is arranged on the front surface of one end of the control box, and the output end of the vacuum motor and the inside of the box body of the control box are expanded.
As a preferred embodiment of the present invention: the utility model discloses a refrigerator, including trapezoidal cabinet, including the cabinet, the cabinet is placed to trapezoidal positive surface, the positive surface of cabinet is placed to trapezoidal is equipped with and is used for articulated upset curb plate, square grooved slot position avris articulates there is a sealed curb plate, the one end of sealed curb plate is equipped with and is used for articulated a controller, the inside of controller embeds has the adjustment button that is used for pressing, the refrigerator that is used for sample cold-stored has been placed to the positive surface avris of bearing the base, refrigerator is including installing the fridge that sets up at bearing the base avris, wherein this fridge box top is equipped with the regulation that is used for the upset and places the lid, the inside of adjusting and placing the lid embeds has a placement box that is used for the intercommunication.
As a preferred embodiment of the present invention: an air compressor used for placing is arranged at the rear end of the placement box, a holding rod is arranged in the middle of the top end of the air compressor, and a toggle button used for pressing is mounted on the front surface of the holding rod in a fitting mode.
Compared with the prior art, the invention has the beneficial effects that:
1) The positions of the bearing base, the square bearing bottom plate and the round sleeve at the upper end are communicated, one end of a cylinder body of the adopted fine adjustment linkage pressing cylinder is placed in a telescopic mode, a user can place the cylinder body according to the top end of the frame body of the trapezoid frame, the user can vertically assemble the cylinder according to the square bearing base and one end of the plate surface of the connecting bearing plate, the positions of a plurality of extracted outer frames are adapted to place, and at the moment, the user can extract and place the cylinder body according to one end of the square slotting;
2) The method comprises the steps that through the fact that one end of a connecting side plate, a control box and a vacuum motor are arranged, chronic leukemia lymphocytes needing to be extracted are communicated after being electrified, then vacuum extraction is carried out, after built-in stamping of a refrigerating box is arranged, the chronic leukemia lymphocytes which are completed in extraction are stored, and the inside of a box body of the overturning side plate and the inside of the control box are sealed, so that the chronic leukemia lymphocytes are purified;
3) Through the drive carousel that is equipped with and corresponding vertical cabinet of placing, realize the distributed support after the vertical support of cabinet body one end, the fridge of adoption is placed with the regulation and is sealed the state of placing the lid processing of lid and place, increase the cold-stored speed of built-in air after combining the circular telegram of air compressor machine and built-in pneumatic cylinder, swing forearm and driving motor that the extraction process adopted control the forearm and realize the upset rotation after driving the rotatory drive roller shaft and further reached the valve body one end of the pneumatic valve of front end and realize the response setting, the articulated connecting rod of adoption realizes the upset injection after articulated holding, it realizes the rotation to draw the completion analysis.
Drawings
The accompanying drawings are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate the invention and together with the embodiments of the invention, serve to explain the invention. In the drawings:
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is a schematic side view of the present invention;
FIG. 3 is a schematic view of the extraction mechanism according to the present invention;
FIG. 4 is a schematic view of a square bearing base structure according to the present invention;
FIG. 5 is a schematic view of a bearing base structure according to the present invention;
FIG. 6 is a schematic view of the arc adjustment bracket of the present invention;
FIG. 7 is a schematic view of the structure of the grip lever of the present invention;
FIG. 8 is a schematic view of a bracket structure in the shape of a Chinese character 'ji';
FIG. 9 is a schematic view of a refrigerator according to the present invention;
FIG. 10 is a schematic view of a square slotting structure of the present invention;
FIG. 11 is an enlarged schematic view of the structure of the cell of the present invention.
In the figure: 1. a placement mechanism; 11. a load-bearing base; 12. a square bearing bottom plate; 13. a trapezoid bearing plate; 14. a circular sleeve; 15. a pneumatic cylinder is connected; 16. a ladder-shaped frame; 17. square placing plate; 18. connecting the bearing plate; 19. a square bearing base; 191. round slotting; 192. a strip-shaped mounting plate; 193. an outer frame; 194. a delivery tube; 195. connecting the vertical rods; 196. a square frame; 2. an extraction mechanism; 21. a cabinet is vertically placed; 22. a first placement bracket; 23. a sliding groove; 24. a turntable base; 25. driving a turntable; 26. a transmission sleeve; 27. an angle limiter; 28. a rotating disc; 29. a rotation shaft; 291. turning over the large arm; 292. a motorized roller; 293. toggle the stay bar; 294. swinging the forearm; 295. driving a roller; 296. a driving motor; 297. a linkage sleeve; 298. an arc-shaped adjusting bracket; 3. an extraction mechanism; 31. a bracket in a shape of a Chinese character 'ji'; 32. an extraction frame; 33. lifting the telescopic cylinder; 34. pneumatically extracting the bracket; 35. a pneumatic valve; 36. detecting a valve table; 37. a connector; 38. an arched grip; 39. a hinged connecting rod; 4. a classification extraction mechanism; 41. a sample extraction rack; 42. a U-shaped clamping frame; 43. arc-shaped toggle support; 44. a drawing frame; 45. concave slotting; 46. a draw sleeve; 47. a drawing piston; 48. a telescopic connecting rod; 49. connecting a stay bar; 491. connecting a needle; 492. square bearing plate; 493. a load bearing bracket; 5. a trapezoid control mechanism; 51. a trapezoid placing cabinet; 52. a second placement bracket; 53. placing a base; 54. placing a bottom plate; 55. a bearing seat; 56. turning over the side plates; 57. square slotting; 58. sealing the side plates; 59. a controller; 71. a trapezoid cabinet; 72. a control cabinet; 73. connecting side plates; 74. a control box; 75. a vacuum motor; 6. a refrigeration mechanism; 61. a refrigerator; 62. adjusting the placement cover; 63. placing a box; 64. an air compressor; 65. a grip lever; 66. the button is toggled.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.
Referring to fig. 1 to 11, the present invention provides the following technical solutions: the utility model provides a chronic leukemia lymphocyte separation extraction element, including a placement machine 1, placement machine 1 is including placing a loading base 11 on ground, wherein square loading bottom plate 12 has been placed to the top surface middle part of this loading base 11, the top middle part of square loading bottom plate 12 is equipped with trapezoidal loading plate 13, a circular sleeve 14 has been seted up to the top surface avris of trapezoidal loading plate 13, a linkage pneumatic cylinder 15 is vertically installed to the top middle part of circular sleeve 14, a ladder frame 16 has been supported to the cylinder body top middle part of linkage pneumatic cylinder 15, square loading plate 17 has been placed to the top middle part of ladder frame 16 in the fixed placement of top, wherein the face top middle part of this square loading plate 17 transversely is equipped with a connection loading plate 18 that is used for supporting, the top middle part of connection loading plate 18 is equipped with a square loading base 19 that is used for magnetism absorption, wherein the top middle part side of this square loading base 19 has been placed and is used for placing side by side circular fluting 191, wherein the middle part of this circular fluting 191 has a bar mounting plate 192, a plurality of independent outer frames 193 in proper order have been laid at the trench middle part of bar mounting plate 192, the top middle part vertical installation pipe 194, the top vertical installation pipe 194 top vertical pole setting of the top pole setting of transfer pipe 194 has a connection pole setting 195, the top pole setting 195 is equipped with a square pole setting 196.
In this embodiment: the rear end of the trapezoid bearing plate 13 is provided with an extraction mechanism 2 for medical extraction;
the extraction mechanism 2 further comprises a vertical placing cabinet 21 placed in the vertical placing cabinet 21, wherein a first placing support 22 is arranged in the middle of a cabinet body of the vertical placing cabinet 21, a sliding groove 23 is linearly arranged in the middle of the top end of the first placing support 22 in a sliding mode, a turntable base 24 used for driving to rotate is attached to the middle of the groove position of the sliding groove 23, a driving turntable 25 is arranged in the middle of the top end of the turntable base 24, a transmission sleeve 26 is vertically arranged at the top of a disk surface of the driving turntable 25, an angle limiter 27 is arranged at the rear end of the transmission sleeve 26, a rotating disk 28 is arranged in the middle of the top end of the angle limiter 27, a rotating shaft 29 is arranged in the middle of the top end of the rotating disk 28, a turnover large arm 291 is arranged at one end of the rotating shaft 29, an electric roller 292 is connected to the middle transmission of the turnover large arm 291, and one end of the electric roller 292 is provided with a stirring supporting rod 293.
The axially rotated state of the turning large arm 291 and the motorized roller 292 realizes driving of the rod stirring state of the toggle stay 293, and free turning of the turning large arm 291 and the turning small arm is achieved.
In this embodiment: the middle part of the top end of the toggle stay rod 293 is provided with a swing small arm 294, the middle part of the swing small arm 294 is provided with a driving roller 295, the middle part of the driving roller 295 is linked and provided with a small arm driving motor 296 for driving rotation, the output end of the small arm driving motor 296 is linked with one end of the driving roller 295, one end of the driving roller 295 is provided with a linkage sleeve 297, and one end of the linkage sleeve 297 is provided with an arc-shaped adjusting bracket 298 for injection.
The rotation is realized by connecting the adopted swing small arm 294 with the pipe fitting of the appointed linkage sleeve 297 and then receiving one end of the specific small arm driving motor 296, and the change of the specific swing small arm 294 angle is realized by adopting one end of the arc-shaped adjusting bracket 298.
In this embodiment: the top mid-mounting of arc regulation support 298 has extraction mechanism 3, extraction mechanism 3 is including installing the several style of calligraphy support 31 that set up in arc regulation support 298 bottom, the vertical extraction frame 32 of establishing on the arc connection surface in top middle part of several style of calligraphy support 31, the bottom of extracting frame 32 is equipped with the flexible jar 33 of lift, the cylinder body bottom of the flexible jar 33 of lift is equipped with a pneumatic extraction support 34 that is used for the tractive, pneumatic extraction support 34's middle part is equipped with a plurality of independent pneumatic valve 35 in proper order, pneumatic valve 35's valve body bottom is equipped with the L type connecting tube 35 that is used for drawing, the bottom middle part cover of L type switch-on hose is equipped with a detection valve table 36 that is used for sealed UNICOM, the bottom mid-mounting of detection valve table 36 has a connector 37, the bottom middle part of connector 37 is corresponding side by side with the conveyer pipe 194 mouth of lower extreme.
The connection of one end of the pneumatic extraction bracket 34 is realized through the connector 37 and the conveying pipe 194, and the L-shaped connecting hose is used for connecting one part of one end which needs to be extracted in an inflation stage.
In this embodiment: the middle part of the top end of the bracket 31 in a shape like a Chinese character 'ji' is hinged with an arched holding frame 38, the side of the bottom of the arched holding frame 38 is obliquely provided with a hinged connecting rod 39, the bottom end of the hinged connecting rod 39 moves up and down with a pneumatic drawing bracket 34 at the lower end, a sorting and extracting mechanism 4 is arranged on the side of the bottom of the vertical placing cabinet 21, the sorting and extracting mechanism 4 comprises an assay drawing bracket 41 arranged on the side wall of the side of the hinged connecting rod 39, the front surface of the assay drawing bracket 41 is provided with a U-shaped clamping frame 42 for clamping, and the middle part of the top end of the U-shaped clamping frame 42 is vertically provided with an arc-shaped stirring bracket 43.
The adopted assay extraction support 41 is used for further realizing extraction of samples required to be extracted from chronic leukemia lymphocytes by connecting the adopted U-shaped clamping frame 42 with one end of the arc-shaped toggle support 43, and then filtering.
In this embodiment: the middle part of the arc-shaped toggle support 43 is provided with an extraction frame 44, the middle part of the top end of the extraction frame 44 is provided with a concave groove 45, the middle part of the groove position of the concave groove 45 is provided with an extraction sleeve 46, the middle part of the top end of the extraction sleeve 46 is provided with an extraction piston 47, and the middle part of the top end of the extraction piston 47 is provided with a telescopic connecting rod 48.
The bottom of the rod body of the telescopic connecting rod 48 is vertically provided with a connecting stay rod 49, one end of the connecting stay rod 49 is provided with a connecting needle 491, the bottom of the connecting needle 491 is provided with a square bearing plate 492, the middle part of the bottom end of the square bearing plate 492 is provided with a bearing bracket 493 for clamping, and the middle part of the bottom end of the connecting stay rod 49 is provided with a trapezoid control mechanism 5.
By using a carrier 493 and a drawing piston 47, the sample to be individually called up by different patients can be individually extracted and the connecting needle 491 can be stored as a long tube channel into the sample tube for feeding into the tube.
In this embodiment: the bottom middle part of trapezoidal control mechanism 5 is equipped with a trapezoidal cabinet 51 of placing, and the inside cavity of the one end cabinet body of cabinet 51 is placed to the trapezoid, and wherein is located the cabinet body upper end of cabinet 51 is placed to the trapezoid and is installed a second and place support 52, and the top mid-mounting of support 52 is placed to the second and is placed the base 53, and the top middle part of placing the base 53 is equipped with a bottom plate 54 of placing that is used for supporting, and the top middle part of placing the bottom plate 54 is equipped with a carrier seat 55 that is used for placing.
The trapezoid placement cabinet 51 and the built-in placement bracket are used for classifying and placing the compressors for temperature control, and the compressors are detected when the compressors are needed to be used in the later period.
In this embodiment: the trapezoidal cabinet 71 is installed to the limit side of bearing seat 55, and the one end of trapezoidal cabinet 71 is equipped with a switch board 72 that is used for the access, and the top middle part of switch board 72 transversely is equipped with a connection curb plate 73, and control box 74 has been placed to the top middle part of connection curb plate 73, and the one end of control box 74 is equipped with and is used for driven positive surface to be equipped with and is used for driven vacuum motor 75, and the extension is realized with the box inside of control box 74 to vacuum motor 75's output.
The control cabinet 72 and the interception side plate are used for limiting the installation of the vacuum motor 75 under the protection of the connecting side plate 73, and the temperature reduction of the built-in pneumatic cylinder is controlled after the vacuum motor 75 is electrified.
In this embodiment: the front surface of the trapezoid containing cabinet 51 is provided with a turnover side plate 56 for hinging, the front surface of the turnover side plate 56 is provided with a square groove 57 for hinging, the side of the groove of the square groove 57 is hinged with a sealing side plate 58, one end of the sealing side plate 58 is provided with a controller 59 for hinging, an adjusting button for pressing is arranged in the controller 59, a refrigerating mechanism 6 for refrigerating samples is arranged on the side of the front surface of the bearing base 11, the refrigerating mechanism 6 comprises a refrigerating box 61 arranged on the side of the bearing base 11, a regulating containing cover 62 for overturning is arranged at the top of the box body of the refrigerating box 61, and a containing box 63 for communicating is arranged in the regulating containing cover 62.
The cover 62 is placed by the support of the cover joint end of the adjustment placement cover and then is assembled and placed uniformly.
In this embodiment: an air compressor 64 for placing is arranged at the rear end of the placement box 63, a holding rod 65 is arranged in the middle of the top end of the air compressor 64, and a toggle button 66 for pressing is attached to the front surface of the holding rod 65.
The rod body supporting states of the air compressor 64 and the holding rod 65 are used for adjusting the clamping of the toggle button 66.
When the method is specifically used, the first step is as follows: extracting white blood cells of a patient:
firstly, a user needs to support the matched position of the bearing base 11, after the supporting is finished, the user needs to realize the up-and-down shifting of the hinged connecting rod 39 at the front end according to the holding state of the arched holding frame 38 at the upper end by hand, in the shifting process, the user can realize the communication after placing one end of the input conveying pipe 194 according to the hinged unit structure at the upper end in the holding state of the arched holding frame 38 at the lower end, further favoring the front end to realize the hinging of the vertical rod 31 for holding the front end, in the hinging process, the L-shaped extracting frame 32 at the upper end is controlled to realize the opening and closing of the extracting frame 32 in the hinging state of the vertical rod 31 in the sample, at the moment, the whole extracting frame 32 can be subjected to the rotation and overturning state of the angle limiter 27 in the specific extracting mechanism 2, the valve body structure of the pneumatic extracting frame 35 is kept to realize the downward shifting after the upward and downward lifting, the end of the input conveying pipe 194 is placed in the end of the input conveying pipe according to the hinged unit structure at the upper end, and then the specified after placing the corresponding vertical rod 193 is realized to realize the specified protection for the middle part of the outer frame 193 after placing the corresponding to the corresponding connection frame 195;
and a second step of: separation of chronic leukemia lymphocytes;
at this time, the user turns over according to one end of the angle limiter 27, turns over according to one end of the transmission sleeve 26, and then realizes the conversion direction of the extraction end, then the user realizes the angular position change according to the end of the linkage sleeve 297, moves the extraction end back and forth, then the user realizes the turning over and stirring in angle according to the forward and backward displacement of the swing small arm 294, then the user can lift and fall according to one end of the square bearing base 19 by a specific cylinder structure, and at this time, the user realizes clamping according to one end of the conveying pipe 194;
after the extraction is finished, clamping is realized according to one end of the assay extraction bracket 41, and then a user is communicated with one end of the pneumatic extraction bracket 34 by the connecting needle 491 for extraction corresponding to the U-shaped clamping bracket 42 and then is replaced to the outside;
and a third step of: one end of the square slot 57 is filled with raw materials in the vertical placement cabinet 21, and the raw materials are placed in the trapezoid placement cabinet 51;
at this time, after the user turns over according to the opening of one end of the turning side plate 56, the chronic leukemia lymphocytes corresponding to the internal communication are placed, after the centrifugal machine is required to be separated, the inside of the box body of the control box 74 is required to be started after the vacuum motor 75 is powered on, and after the stirring and turning over, the middle part of the groove position built in the square groove 57 is driven to be turned over and separated.

Claims (10)

1. The utility model provides a chronic leukemia lymphocyte separation extraction element, includes a placement machine constructs (1), a serial communication port, placement machine constructs (1) including placing one and bear base (11) on ground, wherein the top surface middle part that should bear base (11) has placed square loading board (12), the top middle part that square loading board (12) is equipped with trapezoidal loading board (13), a circular sleeve (14) has been seted up to the top surface avris of trapezoidal loading board (13), a linkage pneumatic cylinder (15) are vertically installed in the top middle part of circular sleeve (14), a trapezoidal frame (16) have been supported to the cylinder body top middle part of linkage pneumatic cylinder (15), square loading board (17) have been placed in the top middle part of trapezoidal frame (16), wherein the face top middle part of this square loading board (17) transversely is equipped with a connection loading board (18) that are used for supporting, the top middle part mid-mounting of connection loading board (18) has a square loading board (19) that are used for magnetic adsorption, and wherein the top middle part of this loading board (19) is equipped with a circular sleeve (14) that is used for placing side by side, and is equipped with a fluting (191) that are arranged side by side, and wherein a vertical pipeline (192) of top that is arranged in proper order, a plurality of strip-shaped middle part of installing plates (192) are arranged at the top of vertical pipeline (192) of installing place in proper order, the middle part of the top end of the conveying pipe (194) is vertically provided with a connecting vertical rod (195), and the top of the rod body of the connecting vertical rod (195) is provided with a square frame (196).
2. The chronic leukemia lymphocyte separation and extraction device according to claim 1, wherein: the rear end of the trapezoid bearing plate (13) is provided with an extraction mechanism (2) for medical extraction;
the extraction mechanism (2) further comprises a vertical placing cabinet (21) placed in the vertical placing cabinet, wherein a first placing support (22) is arranged in the middle of a cabinet body of the vertical placing cabinet (21), a sliding groove (23) is linearly formed in the middle of the top end of the first placing support (22), a turntable base (24) used for driving to rotate is attached to the middle of the groove position of the sliding groove (23), a driving turntable (25) is arranged in the middle of the top end of the turntable base (24), a transmission sleeve (26) is vertically arranged at the top of a disc surface of the driving turntable (25), an angle limiter (27) is arranged at the rear end of the transmission sleeve (26), a rotating disc (28) is arranged in the middle of the top end of the angle limiter (27), a rotating shaft (29) is arranged in the middle of the top end of the rotating disc (28), a turnover large arm (291) is arranged at one end of the rotating shaft, a stirring electric roller (292) is connected with a stirring rod (293) in a middle transmission mode.
3. The chronic leukemia lymphocyte separation and extraction device according to claim 2, wherein: the middle part of the top of stirring vaulting pole (293) is equipped with a swing forearm (294), the middle part of swing forearm (294) is equipped with driving roller (295), the middle part linkage of driving roller (295) is equipped with and drives rotatory forearm driving motor (296), the output of forearm driving motor (296) sets up with the one end linkage of driving roller (295), the one end of driving roller (295) is equipped with linkage sleeve (297), the one end of linkage sleeve (297) is equipped with arc regulation support (298) that are used for the injection.
4. A chronic leukemia lymphocyte separation and extraction device according to claim 3, wherein: the utility model provides a draw-out mechanism (3) is installed to top mid-mounting of arc regulation support (298), draw-out mechanism (3) are including installing several style of calligraphy support (31) that set up in arc regulation support (298) bottom, the vertical extraction frame (32) of establishing on the arc connection surface in top middle part of several style of calligraphy support (31), the bottom of extracting frame (32) is equipped with lift telescopic cylinder (33), the cylinder body bottom of lift telescopic cylinder (33) is equipped with one and is used for the pneumatic extraction support (34) of tractive, the middle part of pneumatic extraction support (34) is equipped with a plurality of independent pneumatic valve (35) in proper order, the valve body bottom of pneumatic valve (35) is equipped with one and is used for drawing L type connection pipe (35), the bottom middle part cover of L type switch-on hose is equipped with one and detects valve table (36) that are used for sealed UNICOM, the bottom mid-mounting of detecting valve table (36) has a connector (37), the bottom middle part of connector (37) is corresponding side by side with conveyer pipe (194) mouth of pipe of lower extreme.
5. The chronic leukemia lymphocyte separation and extraction device according to claim 4, wherein: the device is characterized in that an arch-shaped holding frame (38) is hinged to the middle of the top end of the U-shaped support (31), a hinged connecting rod (39) is obliquely arranged on the side of the bottom of the arch-shaped holding frame (38), the bottom end of the hinged connecting rod (39) moves downwards with a pneumatic drawing support (34) at the lower end in a lifting mode, a classification and extraction mechanism (4) is arranged on the side of the bottom of the vertical placing cabinet (21), the classification and extraction mechanism (4) comprises an assay extraction support (41) arranged on the side wall of the hinged connecting rod (39), a U-shaped holding frame (42) used for holding is arranged on the front surface of the assay extraction support (41), and an arc-shaped stirring support (43) is vertically arranged in the middle of the top end of the U-shaped holding frame (42).
6. The chronic leukemia lymphocyte separation and extraction device according to claim 5, wherein: the middle part of the arc-shaped toggle support (43) is provided with an extraction frame (44), the middle part of the top end of the extraction frame (44) is provided with a concave slot (45), the middle part of the slot position of the concave slot (45) is provided with an extraction sleeve (46), the middle part of the top end of the extraction sleeve (46) is provided with an extraction piston (47), and the middle part of the top end of the extraction piston (47) is provided with a telescopic connecting rod (48);
the telescopic rod is characterized in that a connecting stay bar (49) is vertically arranged at the bottom of the rod body of the telescopic connecting rod (48), a connecting needle head (491) is arranged at one end of the connecting stay bar (49), a square bearing plate (492) is arranged at the bottom of the connecting needle head (491), a bearing support (493) used for clamping is arranged in the middle of the bottom end of the square bearing plate (492), and a trapezoid control mechanism (5) is arranged at the middle of the bottom end of the connecting stay bar (49).
7. The chronic leukemia lymphocyte separation and extraction device according to claim 6, wherein: the bottom middle part of trapezoidal control mechanism (5) is equipped with a trapezoidal cabinet (51) of placing, the inside cavity of one end cabinet body of cabinet (51) is placed to trapezoidal, wherein is located the cabinet body upper end of cabinet (51) is installed a second and is placed support (52), the top mid-mounting of support (52) is placed to the second has a base (53) of placing, the top middle part of placing base (53) is equipped with one and is used for supporting and places bottom plate (54), the top middle part of placing bottom plate (54) is equipped with one and is used for placing and bears seat (55).
8. The chronic leukemia lymphocyte separation and extraction device according to claim 7, wherein: the utility model discloses a vacuum cabinet, including bearing seat (55), control cabinet (72), control cabinet (74) are placed at the top middle part of connection curb plate (73), control cabinet (74) are placed at the top middle part of bearing seat (55), control cabinet (71) are installed to bearing seat (55) avris, one end of trapezoidal cabinet (71) is equipped with a switch board (72) that are used for the access, the extension is realized inside with the box of control cabinet (74) to the output of vacuum motor (75).
9. The chronic leukemia lymphocyte separation and extraction device according to claim 5, wherein: the utility model provides a refrigerator, including trapezoidal cabinet (51) of placing, the front surface of cabinet (51) is equipped with and is used for articulated upset curb plate (56), the front surface of upset curb plate (56) is equipped with and is used for articulated square fluting (57), the position avris of square fluting (57) articulates has a sealed curb plate (58), the one end of sealed curb plate (58) is equipped with and is used for articulated controller (59), the inside of controller (59) is built-in to have and is used for pressing adjusting button, refrigerator (6) that are used for the sample refrigerated are placed to the front surface avris of bearing base (11), refrigerator (6) are including installing a fridge (61) that sets up in bearing base (11) avris, wherein this fridge (61) box top is equipped with and is used for the regulation of upset to place lid (62), the inside of adjusting to place lid (62) is built-in and is used for placing case (63) of intercommunication.
10. The chronic leukemia lymphocyte separation and extraction device according to claim 9, wherein: an air compressor (64) for placing is arranged at the rear end of the placement box (63), a holding rod (65) is arranged in the middle of the top end of the air compressor (64), and a toggle button (66) for pressing is mounted on the front surface of the holding rod (65) in a fitting mode.
CN202311082698.1A 2023-08-25 2023-08-25 Chronic leukemia lymphocyte separation and extraction device Pending CN117106549A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311082698.1A CN117106549A (en) 2023-08-25 2023-08-25 Chronic leukemia lymphocyte separation and extraction device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202311082698.1A CN117106549A (en) 2023-08-25 2023-08-25 Chronic leukemia lymphocyte separation and extraction device

Publications (1)

Publication Number Publication Date
CN117106549A true CN117106549A (en) 2023-11-24

Family

ID=88812378

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202311082698.1A Pending CN117106549A (en) 2023-08-25 2023-08-25 Chronic leukemia lymphocyte separation and extraction device

Country Status (1)

Country Link
CN (1) CN117106549A (en)

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