CN117018110A - Medicament for removing necrotic tissue and promoting tissue regeneration and preparation method thereof - Google Patents
Medicament for removing necrotic tissue and promoting tissue regeneration and preparation method thereof Download PDFInfo
- Publication number
- CN117018110A CN117018110A CN202311230816.9A CN202311230816A CN117018110A CN 117018110 A CN117018110 A CN 117018110A CN 202311230816 A CN202311230816 A CN 202311230816A CN 117018110 A CN117018110 A CN 117018110A
- Authority
- CN
- China
- Prior art keywords
- parts
- medicine
- promoting
- pain
- vaseline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 39
- 230000001737 promoting effect Effects 0.000 title claims abstract description 30
- 230000001338 necrotic effect Effects 0.000 title claims abstract description 11
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 230000017423 tissue regeneration Effects 0.000 title claims description 12
- 239000002674 ointment Substances 0.000 claims abstract description 21
- 238000005469 granulation Methods 0.000 claims abstract description 12
- 230000003179 granulation Effects 0.000 claims abstract description 12
- 229940099259 vaseline Drugs 0.000 claims abstract description 12
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 10
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims abstract description 10
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 10
- 244000080767 Areca catechu Species 0.000 claims abstract description 10
- 235000006226 Areca catechu Nutrition 0.000 claims abstract description 10
- 240000007311 Commiphora myrrha Species 0.000 claims abstract description 10
- 235000006965 Commiphora myrrha Nutrition 0.000 claims abstract description 10
- 235000007265 Myrrhis odorata Nutrition 0.000 claims abstract description 10
- 229940116229 borneol Drugs 0.000 claims abstract description 10
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 10
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 10
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims abstract description 10
- 210000001519 tissue Anatomy 0.000 claims abstract description 10
- 235000003717 Boswellia sacra Nutrition 0.000 claims abstract description 9
- 240000007551 Boswellia serrata Species 0.000 claims abstract description 9
- 235000012035 Boswellia serrata Nutrition 0.000 claims abstract description 9
- 239000004863 Frankincense Substances 0.000 claims abstract description 9
- 241001071917 Lithospermum Species 0.000 claims abstract description 9
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 9
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 230000036772 blood pressure Effects 0.000 claims abstract description 3
- 239000008280 blood Substances 0.000 claims description 12
- 210000004369 blood Anatomy 0.000 claims description 12
- 210000000436 anus Anatomy 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 230000013872 defecation Effects 0.000 claims description 3
- 238000000227 grinding Methods 0.000 claims description 2
- 238000005303 weighing Methods 0.000 claims description 2
- 230000036407 pain Effects 0.000 abstract description 31
- 208000002193 Pain Diseases 0.000 abstract description 30
- 230000000694 effects Effects 0.000 abstract description 14
- 230000000740 bleeding effect Effects 0.000 abstract description 7
- 230000008961 swelling Effects 0.000 abstract description 7
- 206010048038 Wound infection Diseases 0.000 abstract description 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 2
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 2
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 2
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 15
- 208000035861 hematochezia Diseases 0.000 description 15
- 229940079593 drug Drugs 0.000 description 12
- 201000010099 disease Diseases 0.000 description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 208000024891 symptom Diseases 0.000 description 8
- 208000032843 Hemorrhage Diseases 0.000 description 6
- 230000035876 healing Effects 0.000 description 6
- 206010042674 Swelling Diseases 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 206010052428 Wound Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 208000014617 hemorrhoid Diseases 0.000 description 4
- 208000025865 Ulcer Diseases 0.000 description 3
- 206010053692 Wound complication Diseases 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 210000003608 fece Anatomy 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 2
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 241000282414 Homo sapiens Species 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 206010036772 Proctalgia Diseases 0.000 description 2
- 208000015815 Rectal disease Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 235000019643 salty taste Nutrition 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010048946 Anal abscess Diseases 0.000 description 1
- 206010002153 Anal fissure Diseases 0.000 description 1
- 208000016583 Anus disease Diseases 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- 241000130781 Arnebia Species 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 208000009531 Fissure in Ano Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 229920000175 Pistacia lentiscus Polymers 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000004680 Rectal Fistula Diseases 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 206010002156 anal fistula Diseases 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 235000019606 astringent taste Nutrition 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000028709 inflammatory response Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 201000009890 sinusitis Diseases 0.000 description 1
- 230000036560 skin regeneration Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 206010042772 syncope Diseases 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 229940126702 topical medication Drugs 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Zoology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention belongs to the field of traditional Chinese medicines, and discloses a medicine for removing necrotic tissue and promoting granulation, and a preparation method and application thereof. The invention discloses a medicine raw material comprising: 20-30 parts of rubber, 20-30 parts of blood pressure, 20-30 parts of red halloysite, 20-30 parts of frankincense, 20-30 parts of dragon bone, 20-30 parts of myrrh, 20-30 parts of catechu, 2-5 parts of borneol, 2-5 parts of lithospermum oil and 5-10 parts of vaseline. The ointment prepared by the compatibility of nine traditional Chinese medicine components has the effects of clearing heat and detoxicating, reducing swelling and relieving pain, can effectively inhibit wound infection, has strong antibacterial and anti-inflammatory forces, can stop bleeding and relieve pain, can promote skin repair, and has quick curative effect and low cost.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a medicine for removing putrefaction and promoting granulation and a preparation method thereof.
Background
In recent years, the incidence rate of anorectal diseases is higher and higher, and many people in life suffer from anorectal diseases, namely various diseases occurring on anus and large intestine, which are typical and frequently occurring diseases of human beings, and commonly include internal hemorrhoids, external hemorrhoids, mixed hemorrhoids, anal fissure, anal fistula, perianal abscess, hematochezia, anal sinusitis and the like. Clinical presentation shows that most perianal diseases are caused by bad life.
Most people have the experience that the delay and forgetting to defecation are bad habits of many people when sitting on buses and when working is tension. Thus, the feces can be accumulated in the intestinal tract for a long time, and the feces are dry along with water loss, so that the feces are more difficult to discharge again, and the constipation is marked. Constipation for a long period of time can easily cause hemorrhoids. Newspaper reading and mobile phone playing are habits of many people when squatting and toilet. Research shows that after ten minutes of squatting toilet, anus will receive certain oppression, produces the influence to anus health. Or the anus health is possibly influenced by little drinking water, bad dressing habit, insufficient exercise quantity and long standing and sitting in life.
Currently, the art is primarily concerned with perianal disease by saline irrigation, topical medications, oral medications, infrared therapy or surgery. However, the saline water washing has general therapeutic effect on perianal diseases; the topical medicine is suitable for patients with mild symptoms; oral administration of the drug can only help recovery of the disease by reducing the inflammatory response of the body, and the effect is not ideal; the infrared treatment requires professional operation of doctors and is complicated; although the operation treatment can effectively relieve the perianal diseases, the operation treatment still has the defects of easy recurrence, high price and the like. Therefore, how to provide a method for treating perianal diseases, which has low price, simple use and can effectively treat perianal diseases, diminish inflammation and sterilize and promote skin regeneration, becomes the problem to be solved by the invention.
Disclosure of Invention
In view of the above, the invention provides a medicament capable of removing necrotic tissue and promoting tissue regeneration and a preparation method thereof, and the medicament is prepared into ointment by matching nine Chinese herbal medicines, has the advantages of convenient use, low price, rapid curative effect, and effective hemostasis, pain relieving and tissue regeneration promoting.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
the medicine for removing the necrotic tissue and promoting tissue regeneration comprises the following components in parts by weight:
20-30 parts of rubber, 20-30 parts of blood pressure, 20-30 parts of red halloysite, 20-30 parts of frankincense, 20-30 parts of dragon bone, 20-30 parts of myrrh, 20-30 parts of catechu, 2-5 parts of borneol, 2-5 parts of lithospermum oil and 5-10 parts of vaseline.
The beneficial effects of the technical scheme are that:
the prescription of the invention is mainly formed by combining natural medicines, does not exclude the use of artificial synthetic medicines, and is formed by organically combining various medicines. The preparation method is fixed, the use method is clear, the preparation is designed for unspecified people, and the effect is obvious.
The traditional Chinese medicine formula is relatively complex in components, and from the perspective of traditional Chinese medicine, the traditional Chinese medicine formula takes the basic theory of traditional Chinese medicine as a principle, blood force as monarch drug, rubber, red halloysite, dragon bone and catechu as ministerial drugs, frankincense, myrrh, borneol and lithospermum oil as adjuvant drugs, and after a plurality of drugs are organically combined into a traditional Chinese medicine preparation, the composition drugs are mutually coordinated and the curative effect is obviously enhanced, and meanwhile, the toxicity of certain drugs is reduced or alleviated, so that the drug treatment effect is better exerted. In addition, the medicines are combined into a prescription, so that the medicine can be better suitable for complex diseases.
And (3) rubber: salty taste, warm taste, functional indications: promoting blood circulation, stopping bleeding, healing sore and all wounds, and the ulcers are not closed for a long time;
blood force: sweet, salty, flat, mainly: removing blood stasis, relieving pain, promoting blood circulation, and promoting granulation, and can be used for treating traumatic hemorrhage;
halloysitum rubrum: sweet and sour nature, astringency and warmth, and mainly treats: astringing to stop bleeding, promoting granulation, astringing intestine, and relieving diarrhea;
keel: sweet, astringent and flat nature, and has the main functions of: tranquillizing, arresting sweating, astringing essence, promoting tissue regeneration, and healing sore, and treating chronic ulcer without healing by external application;
catechu: bitter, astringent and slightly cold in nature, and mainly treats: clearing heat and resolving phlegm, healing sore and stopping bleeding, activating blood and promoting tissue regeneration, and treating sores and ulcers for a long time without healing;
mastic gum: pungent, bitter and slightly warm in nature, and mainly treats: promoting blood circulation, activating qi-flowing, dredging channels, relieving pain, detumescence, promoting granulation, relieving pain of heart and abdomen, rheumatalgia, traumatic stasis, carbuncle, swelling and toxic substance, and promoting wound healing;
myrrh: bitter and flat nature, and mainly treats: promoting blood circulation, relieving pain, detumescence, promoting granulation, removing blood stasis and pain of chest and abdomen, traumatic injury, carbuncle, swelling, pain, acute appendicitis, conjunctival congestion and swelling and pain;
borneol: pungent and pungent. Bitter and slightly cold, mainly functions: inducing resuscitation, refreshing mind, clearing heat, and relieving pain, and can be used for treating fever unconsciousness, convulsion, apoplexy, phlegm syncope, speckle and conjunctival congestion, aphtha, and laryngopharynx swelling and pain;
arnebia oil: dry nature, salty taste, cold nature, and its main indications: clearing heat and cooling blood, promoting blood circulation and removing toxic substances, promoting eruption and eliminating ecchymoses, and also can be used as a lubricant.
Further, the ratio of the raw materials is preferably as follows: 30 parts of rubber, 30 parts of blood force, 30 parts of red halloysite, 30 parts of frankincense, 30 parts of dragon bone, 30 parts of myrrh, 30 parts of catechu, 2 parts of borneol, 2 parts of lithospermum oil and 5 parts of vaseline.
A preparation method of a medicine for removing necrotic tissue and promoting granulation comprises the following steps:
(1) Weighing the raw materials according to the weight part of claim 1;
(2) Grinding the nine raw materials into fine powder respectively;
(3) Mixing the powder obtained in step (2) uniformly, adding vaseline, mixing uniformly, and making into ointment.
Further, the concentration ratio of the ointment Chinese medicinal ointment to the vaseline is 10% -30%.
The application method of the ointment for removing the necrotic tissue and promoting tissue regeneration prepared by the invention comprises the following steps: the patient is cleaned by clear water before defecation, 1 to 1.5 g of the medicine is applied or received on the anus, 2 times a day, ten days is a treatment course.
The beneficial effects of the technical scheme are that:
the ointment prepared by the invention has the effects of clearing heat and detoxicating, detumescence and relieving pain, can effectively control wound infection, accelerate wound healing, has strong antibacterial and anti-inflammatory forces, can stop bleeding, relieve pain, promote granulation, and has low cost and convenient use.
Detailed Description
The following description of the technical solutions in the embodiments of the present invention will be clear and complete, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
A medicine for removing putrefaction and promoting granulation comprises the following components:
20 parts of rubber, 20 parts of blood force, 20 parts of red halloysite, 20 parts of frankincense, 20 parts of dragon bone, 20 parts of myrrh, 20 parts of catechu, 2 parts of borneol, 2 parts of lithospermum oil and 5 parts of Vaseline.
Example 2
A medicine for removing putrefaction and promoting granulation comprises the following components:
25 parts of rubber, 25 parts of blood force, 25 parts of red halloysite, 25 parts of frankincense, 25 parts of dragon bone, 25 parts of myrrh, 25 parts of catechu, 4 parts of borneol, 4 parts of lithospermum oil and 7 parts of Vaseline.
Example 3
A medicine for removing putrefaction and promoting granulation comprises the following components:
30 parts of rubber, 30 parts of blood force, 30 parts of red halloysite, 30 parts of frankincense, 30 parts of dragon bone, 30 parts of myrrh, 30 parts of catechu, 5 parts of borneol, 5 parts of lithospermum oil and 10 parts of vaseline.
Verification of clinical treatment effect
Case 1: some Liu, men, 63 years old, the patient starts to have a small amount of hematochezia in 2010, has no pain, is not cared at that time, and does not take therapeutic measures; symptoms aggravate after 2017, and the long-term hematochezia and anus pain.
After the ointment prepared by the invention is applied, pain is relieved within 1h, the hematochezia amount is reduced, and after the ointment is continuously applied for 5 days, the symptoms disappear, and the ointment has obvious treatment effect and no hematochezia and pain.
Case 2: some plum, men, 90 years old, the patient has no cause of perianal swelling pain, crumbling and pus flowing, postoperative wound pain and occasional bleeding in 2019.
After the ointment prepared by the invention is smeared, pain is relieved within 1 hour, the blood volume is reduced, the wound is lubricated and glossy, the operation wound is basically healed after being smeared for ten days, the ointment is in a normal state, no hematochezia and pain are caused, and the treatment effect is obvious.
Case 3: a man, 85 years old, the patient had hematochezia before and after 2008, and had no other symptoms, but was not treated; in 2015, the symptoms are aggravated, hematochezia is increased, and pain is hard to be felt; wound edema and pain after operation.
After the ointment prepared by the invention is applied, pain is gradually relieved, bleeding amount is gradually reduced within 2 hours, edema disappears after ten days of continuous application, wound is free from infection, hematochezia and pain are avoided, and the ointment is basically cured and has remarkable treatment effect.
Case 4: some men in Song, 84 years old, the patient had hematochezia in 2010, the symptoms were light, and the hematochezia was increased in 2023, and the patient had pain and distention feeling.
After the ointment prepared by the invention is coated, the pain is relieved, the pain is free from falling and swelling feeling after three days of continuous coating, the hematochezia amount is relieved, and the ointment is coated for five days again, and has obvious treatment effect without pain, hematochezia and disappearance of symptoms.
Case 5: some men are born for 83 years, the patient has no cause of anal pain, no hematochezia and hard anus in 2020.
After the ointment prepared by the invention is applied, pain is relieved within 2 hours, symptoms disappear after the ointment is continuously applied for one week, pain is avoided, the package blocks become soft, and the treatment effect is obvious.
200 cases of clinical cases were summarized and the results shown in Table 1 were summarized.
TABLE 1
Through years of clinical application, the effective rate of the ointment for treating hematochezia, pain, anus Zhou Zhongzhang and difficult sore healing can reach more than 92.5%.
In the present specification, each embodiment is described in a progressive manner, and each embodiment is mainly described in a different point from other embodiments, and identical and similar parts between the embodiments are all enough to refer to each other.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (5)
1. The medicine for removing the necrotic tissue and promoting tissue regeneration is characterized by comprising the following components in parts by weight:
20-30 parts of rubber, 20-30 parts of blood pressure, 20-30 parts of red halloysite, 20-30 parts of frankincense, 20-30 parts of dragon bone, 20-30 parts of myrrh, 20-30 parts of catechu, 2-5 parts of borneol, 2-5 parts of lithospermum oil and 5-10 parts of vaseline.
2. The medicine for removing putrefaction and promoting tissue regeneration according to claim 1, wherein the ratio of the raw materials is preferably as follows:
30 parts of rubber, 30 parts of blood force, 30 parts of red halloysite, 30 parts of frankincense, 30 parts of dragon bone, 30 parts of myrrh, 30 parts of catechu, 2 parts of borneol, 2 parts of lithospermum oil and 5 parts of vaseline.
3. The preparation method of the medicine for removing the necrotic tissue and promoting tissue regeneration according to claim 1 or 2, which is characterized by comprising the following steps:
(1) Weighing raw materials according to the weight portion;
(2) Grinding the nine raw materials into fine powder respectively;
(3) Mixing the powder obtained in step (2) uniformly, adding vaseline, mixing uniformly, and making into ointment.
4. The method for preparing a medicine for removing necrotic tissue and promoting granulation according to claim 3, wherein the concentration ratio of the ointment to the vaseline is 10% -30%.
5. The method for using the medicament for removing the necrotic tissue and promoting tissue regeneration prepared by the claims 3 to 4 is characterized by comprising the following steps:
the patient is cleaned by clear water before defecation, 1 to 1.5 g of the medicine is applied or received on the anus, 2 times a day, ten days is a treatment course.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311230816.9A CN117018110A (en) | 2023-09-22 | 2023-09-22 | Medicament for removing necrotic tissue and promoting tissue regeneration and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311230816.9A CN117018110A (en) | 2023-09-22 | 2023-09-22 | Medicament for removing necrotic tissue and promoting tissue regeneration and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117018110A true CN117018110A (en) | 2023-11-10 |
Family
ID=88643398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311230816.9A Pending CN117018110A (en) | 2023-09-22 | 2023-09-22 | Medicament for removing necrotic tissue and promoting tissue regeneration and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN117018110A (en) |
-
2023
- 2023-09-22 CN CN202311230816.9A patent/CN117018110A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103230493B (en) | Traditional Chinese medicine composition for treating unhealed wound | |
| CN103230491A (en) | Orally taken and external combined miao medicine for treating haemorrhoids and preparation method thereof | |
| CN102335309B (en) | Formula of ointment for treating burns and scalds | |
| CN103893557A (en) | Traditional Chinese medicine preparation for treating bedsore | |
| CN102784316B (en) | Cancer inhibition and flesh engendering medicine for treating burns, scalds, internal and external ulcer and cataract, and its preparation method | |
| CN111529592A (en) | Traditional Chinese medicine composition for preventing and treating hemorrhoids and preparation method thereof | |
| CN100548327C (en) | Medicine for external use of treatment tickling dermatosis and preparation method thereof | |
| CN103040900B (en) | Medicine for treating bedsores | |
| CN117018110A (en) | Medicament for removing necrotic tissue and promoting tissue regeneration and preparation method thereof | |
| CN100588412C (en) | Chinese medicine composition for curing fracture | |
| CN101406579B (en) | Novel use of pinellia | |
| CN101073653A (en) | Chinese-medicinal powder for treating acne | |
| CN103735928A (en) | Chinese medicinal mixture for treating perianal abscess | |
| CN109675008B (en) | Traditional Chinese medicine composition for preventing and treating postpartum urinary retention and preparation method and application thereof | |
| CN103816381A (en) | Medicine for treating traumatic injuries and preparation method thereof | |
| CN102885893A (en) | Pharmaceutical composition for treating haemorrhoids | |
| CN103394009B (en) | Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method | |
| CN115957257B (en) | Traditional Chinese medicine composition for treating constipation, patch and preparation method thereof | |
| CN110403995B (en) | Traditional Chinese medicine composition for treating superficial phlebitis and preparation, use methods and application thereof | |
| CN107375811A (en) | A kind of composition of medicine formula for treating hemorrhoid and its preparation and application | |
| CN108853297A (en) | A kind of external application Chinese medicine for treating traumatic injury | |
| CN105055499A (en) | Navel-therapy prescription for treating chronic pelvic inflammatory diseases and preparation method thereof | |
| CN118078894A (en) | Traditional Chinese medicine composition for preventing and treating postoperative complications of hemorrhoids | |
| CN116570555A (en) | Gynecological light guide gel and preparation method thereof | |
| CN117159642A (en) | Pill for nourishing yin and relaxing bowels |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |