CN117017209A - Method and device for locking single sweat gland - Google Patents
Method and device for locking single sweat gland Download PDFInfo
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- CN117017209A CN117017209A CN202310752051.9A CN202310752051A CN117017209A CN 117017209 A CN117017209 A CN 117017209A CN 202310752051 A CN202310752051 A CN 202310752051A CN 117017209 A CN117017209 A CN 117017209A
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- sweat
- wearable patch
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- collecting cavities
- cavities
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- 210000000106 sweat gland Anatomy 0.000 title claims abstract description 102
- 238000000034 method Methods 0.000 title claims abstract description 17
- 210000004243 sweat Anatomy 0.000 claims abstract description 154
- 230000003287 optical effect Effects 0.000 claims abstract description 18
- 238000007599 discharging Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 238000005259 measurement Methods 0.000 description 7
- 238000004458 analytical method Methods 0.000 description 4
- 239000000090 biomarker Substances 0.000 description 4
- 230000007423 decrease Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 description 1
- 238000004987 plasma desorption mass spectroscopy Methods 0.000 description 1
- -1 polydimethylsiloxane Polymers 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910001414 potassium ion Inorganic materials 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
- A61B5/4261—Evaluating exocrine secretion production
- A61B5/4266—Evaluating exocrine secretion production sweat secretion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Physiology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
The invention discloses a method and a device for locking single sweat glands, which utilize sweat gland density values of a target part of a body, design the number of sweat collecting cavities on a wearable patch and the opening area of each collecting cavity at the position where the sweat collecting cavities contact skin based on the distribution law of Poisson distribution, and the designed wearable patch is worn on the target part of the body for measuring sweat gland density randomly, so that the fact that the collecting cavities only containing single sweat glands exist on the patch can be effectively ensured, and a unit containing single sweat glands is identified through an optical sensor and the sweat discharge characteristics of the single sweat glands are analyzed. The invention solves the problem that single sweat glands can not be separated and locked when the independent wearable patch is worn randomly, and the power assisting device is suitable for analyzing sweat secreted by the single sweat glands and the wearable sensing product.
Description
Technical Field
The invention belongs to the technical field of sweat detection, and particularly relates to a method and a device for locking a single sweat gland.
Background
Sweat contains various biomarkers which are equivalent to blood and are related to human health conditions, such as electrolytes, metabolites, amino acids, proteins, hormones and the like, and the purpose of noninvasively, real-time and continuously collecting and analyzing the human health conditions can be achieved by detecting sweat, so that sweat sensing has extremely high value in the aspects of motion monitoring, disease diagnosis, telemedicine and the like.
In addition to being affected by the health condition of the human body, the sweat components and content discharged by the individual in the same state are significantly affected by the sweat rate of the individual sweat glands. For example, the concentration of sodium and chloride ions in human sweat increases with increasing sweat rate, the concentration of potassium and calcium ions decreases with increasing sweat rate, the pH is acidic (pH 3.5-6.0) at low sweat rate, the sweat pH is slightly alkaline (pH 7.0-8.5) at Gao Han, the lactic acid and urea concentrations are higher at low sweat rate, gradually decreases with increasing sweat rate, and so on. Therefore, when detecting and analyzing the concentration of the biomarker in sweat, the sweat rate of a human body needs to be synchronously measured, and the measurement result of the concentration of the biomarker is corrected by using the biomarker, so that the measurement result has comparability, and the aim of diagnosing the health of the human body by using the measurement result of sweat is fulfilled.
However, the sweat analyzed by the existing sweat sensing system (comprising a wearable sweat sensing system, an off-line measuring system and the like) is a mixture of sweat discharged by a plurality of sweat glands in an area, however, in view of the nature of intermittent active sweat discharge of sweat glands, the time and the rate of active sweat discharge of different sweat glands in a unit area are inconsistent, and the total number of active sweat discharge sweat glands in the unit area changes nonlinearly along with the sweat discharge rate; the sweat rate and marker concentration measurement results based on the average value of a plurality of sweat glands cannot accurately reflect the sweat condition of a single sweat gland, and thus, the accurate health diagnosis based on sweat analysis is difficult. It is imperative to measure sweat secreted by a single sweat gland.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a method and a device for locking a single sweat gland. The sweat collecting cavities on the wearable patch and the opening area of each collecting cavity, which are designed according to the distribution law of Poisson distribution, are designed by utilizing the sweat density value of the specific part of the body, and the wearable patch designed according to the sweat collecting cavity number and the opening area of each collecting cavity, which is worn on the specific part of the body for measuring sweat density, can effectively ensure that the collecting cavities only containing single sweat glands exist on the patch, identify the units containing the single sweat glands through the optical sensor and analyze the sweat release characteristics of the single sweat glands. The invention solves the problem that single sweat glands can not be separated and locked when the independent wearable patch is worn randomly, and the power assisting device is suitable for analyzing sweat secreted by the single sweat glands and the wearable sensing product.
The invention is realized by the following technical scheme:
a method of locking a single sweat gland comprising the steps of:
step 1, shooting an image of a target skin area, identifying sweat glands capable of discharging sweat in the target skin area in the image, and calculating sweat gland density of the target skin area;
step 2, determining the number of sweat collecting cavities on the wearable patch and the opening area of the sweat collecting cavities at the contact skin based on the poisson distribution principle according to the sweat gland density of the target skin area obtained in the step;
step 3, manufacturing the wearable patch according to the quantity of sweat collecting cavities and the opening area of the sweat collecting cavities, which are determined in the step 2, at the position where the sweat collecting cavities contact the skin;
and 4, after the wearable patch is manufactured, the wearable patch is stuck to a target skin area to be detected, so that the sweat collecting cavity only containing a single sweat gland can be realized on the wearable patch with high probability.
In the above technical scheme, in step 2, a distribution law P of Poisson distribution of n sweat glands in a single sweat collecting cavity is set n Is the number n of sweat glands actually contained therein and the average sweat gland number contained therein<n>Is a function of:
setting the opening area S of the sweat collecting cavity at the contact position with the skin, and calculating the average number of sweat glands in the single sweat collecting cavity based on the sweat gland density a of the target skin area obtained in the step 2<n>，<n>a.S by applying poisson distribution principle shown in formula (1), calculating probability P of sweat collecting cavity containing n sweat glands n N is 0, 1 or 2, and the probability of 0 sweat glands contained in all N sweat collecting cavities in the set wearable patch is R, namely P 0 N =r, the number of sweat collection chambers required can be calculated; wherein, the probability R that all N sweat collecting cavities contain 0 sweat glands can be set as a minimum probability value; wearable patches designed according to the opening area and the number of sweat collecting cavities, and probability that all sweat collecting cavities do not contain sweat glandsWill only be a set minimum probability value where the probability of having a sweat collecting cavity containing a single sweat gland will be extremely high, thereby effectively ensuring that there is a sweat collecting cavity containing only a single sweat gland on the wearable patch.
The invention also provides a device for realizing the method for locking the single sweat gland, which comprises: the sweat collecting device comprises an optical sensing system and a wearable patch, wherein the wearable patch comprises a plurality of sweat collecting cavities, the number of the sweat collecting cavities and the opening area of the sweat collecting cavities, which are contacted with skin, are determined according to sweat gland density in a target skin area to be detected and based on the distribution law of Poisson distribution; wherein sweat gland density within the target skin area is measured by an optical sensing system.
In the above technical scheme, the optical sensing system comprises an infrared micro-distance camera and an image processor, and the optical sensing system is integrally arranged in the cavity.
In the above technical solution, the arrangement form of the sweat collecting cavities on the wearable patch is not limited, and may be rectangular lattice arrangement or random arrangement.
In the above-described embodiments, the shape of the opening of all sweat collecting cavities on the wearable patch is not limited, and is preferably a circular opening.
In the above-described embodiments, the thickness of the wearable patch should be as small as possible, preferably within 1mm, even within 500 μm, within 100 μm, etc.
In the above technical solution, the inner diameter of the sweat collecting cavity may be of equal diameter.
In the technical scheme, the inner diameter of the sweat collecting cavity is gradually reduced from bottom to top, and the gradually reduced structure can effectively reduce the volume of the collecting cavity and accelerate the sweat filling the collecting cavity and the subsequent measurement and analysis process.
In the technical scheme, a circle of protrusions are respectively arranged on the periphery of the bottom opening of each sweat collecting cavity on the bottom surface of the wearable patch, so that different sweat collecting cavities are isolated from each other.
The invention has the advantages and beneficial effects that:
the sweat collecting cavities on the wearable patch and the opening area of each collecting cavity, which are designed according to the distribution law of Poisson distribution, are designed by utilizing the sweat density value of the specific part of the body, and the wearable patch designed according to the sweat collecting cavity number and the opening area of each collecting cavity, which is worn on the specific part of the body for measuring sweat density, can effectively ensure that the collecting cavities only containing single sweat glands exist on the patch, identify the units containing the single sweat glands through the optical sensor and analyze the sweat release characteristics of the single sweat glands. The invention solves the problem that single sweat glands can not be separated and locked when the independent wearable patch is worn randomly, and the power assisting device is suitable for analyzing sweat secreted by the single sweat glands and the wearable sensing product.
Drawings
Fig. 1 is a schematic view of an apparatus used in the method for locking a single sweat gland according to the present invention.
Fig. 2 is an image of a human target skin area taken by an infrared macro camera.
Fig. 3 is a flow chart of the invention for determining the number of sweat collecting cavities and the open area of sweat collecting cavities on a wearable patch based on poisson distribution principles.
Fig. 4 is a schematic illustration of the arrangement of sweat collecting chambers on a wearable patch (sweat collecting chambers are of equal diameter configuration).
Fig. 5 is a cross-sectional view of the single sweat collection chamber of fig. 4.
Fig. 6 is a schematic illustration of the arrangement of sweat collecting chambers on a wearable patch (sweat collecting chambers are of equal diameter configuration).
Fig. 7 is a schematic illustration of the arrangement of sweat collecting chambers on a wearable patch (sweat collecting chambers in a tapered configuration).
Fig. 8 is a cross-sectional view of the single sweat collection chamber of fig. 7.
Fig. 9 is a schematic view of a human skin surface.
Fig. 10 is a schematic view of a raised structure provided on the bottom surface of a wearable patch (sweat collecting cavity is of equal diameter).
Fig. 11 is a schematic view of a raised structure provided on the bottom surface of a wearable patch (sweat collecting cavity in a tapered configuration).
Other relevant drawings may be made by those of ordinary skill in the art from the above figures without undue burden.
Detailed Description
In order to make the person skilled in the art better understand the solution of the present invention, the following describes the solution of the present invention with reference to specific embodiments.
A method of locking individual sweat glands, which can be achieved by means of the device shown in fig. 1, in particular comprising: an optical sensing system 100 and a wearable patch 200. The optical sensing system 100 comprises an infrared micro-distance camera 102 and an image processor 101, and the optical sensing system 100 can be integrally arranged in the cavity 103, so that the illumination condition of the working environment of the optical sensor is consistent and is not influenced by the external environment; the wearable patch 200 has a plurality of sweat collecting cavities 201, and when the wearable patch 200 is applied to the skin surface of a human body, sweat collecting cavities 201 may contain sweat glands 301 capable of perspiration or only skin 300 does not contain any sweat glands.
The number of sweat collecting cavities 301 on the wearable patch and the opening area of the sweat collecting cavities 301 at the contact skin are designed according to sweat gland density in the target skin area to be detected and based on the poisson distribution rule, so that the designed wearable patch can effectively ensure that the sweat collecting cavities only containing single sweat glands exist on the wearable patch when the wearable patch is attached to the target skin area. Wherein sweat gland density that can sweat within the target skin area is measured by the optical sensing system 100. As shown in fig. 2, the sweating process is an effective means for reducing the body temperature, the temperature at the outlet of sweat glands is lower than the temperature of surrounding skin, the infrared macro camera 102 is used for shooting an image of a target skin area of a human body, and the image processor 101 can identify points with lower temperature than the surrounding area in the image, so that sweat glands 301 'and surrounding skin 302' capable of sweat in the target skin area are identified, and the sweat gland density of the target skin area is calculated.
The method for locking the single sweat gland by using the device is specifically described below, and comprises the following steps:
step 1, shooting an image of a target skin area, identifying sweat glands capable of discharging sweat in the target skin area in the image, and calculating sweat gland density of the target skin area.
Step 2, determining the number of sweat collecting cavities 301 on the wearable patch and the opening area of the sweat collecting cavities 301 contacting the skin based on the poisson distribution principle according to the sweat gland density of the target skin area obtained in the step.
Let P be the poisson distribution of n sweat glands in a single sweat collecting chamber n Is the number n of sweat glands actually contained therein and the average sweat gland number contained therein<n>Is a function of:
according to the procedure shown in FIG. 3, the open area S (mm) of the sweat collecting chamber where it contacts the skin is set 2 ) Sweat gland density a (root/mm) based on the target skin region obtained in step 2 2 ) Calculating the average number of sweat glands in a single sweat collecting cavity<n>，<n>= a.S, and calculating the probability P of sweat gland contained n (such as 0, 1, 2, etc.) sweat glands in the sweat collecting cavity by applying poisson distribution principle shown in formula (1) n (namely, the distribution law of sweat glands, the probability that the number of sweat collecting cavities containing sweat glands with different numbers of 0, 1, 2 and the like in the total number of sweat collecting cavities on the wearable patch shows the Poisson distribution) is R, namely P, according to the probability that all N sweat collecting cavities in the set wearable patch contain 0 sweat glands 0 N =r, the number of sweat collection chambers required can be calculated. Wherein the probability R that all N sweat collecting chambers contain 0 sweat glands can be set to a minimum probability value (e.g., 0.1%, 0.5%, 1%, etc., preferably less than 5% or even 1%); the probability that all sweat collecting cavities do not contain sweat glands will only be the minimum probability value set, wherein the probability of having sweat collecting cavities containing single sweat glands will be extremely large, thereby effectively ensuring that sweat collecting cavities containing only single sweat glands exist on the wearable patch.
Step 3, manufacturing the wearable patch according to the number of sweat collecting cavities 301 on the wearable patch and the opening area of the sweat collecting cavities 301 contacting the skin, which are determined in step 2.
The arrangement of sweat collecting cavities 301 on the wearable patch is not limited, and may be rectangular lattice arrangement (fig. 4) or random arrangement (fig. 6); the shape of the opening of all sweat collecting cavities on the wearable patch is also not limited, and is preferably a circular opening.
Because of the small amount of perspiration from individual sweat glands, the thickness of the wearable patch (i.e., sweat collecting cavity height) should be as small as possible, preferably within 1mm, even within 500 μm, within 100 μm, etc., to achieve the goal of rapid analysis.
In addition to the smaller sweat collection chamber height, the shape of the interior of the sweat collection chamber is a central factor affecting its volume, and referring to fig. 4 and 5, the inner diameter of the sweat collection chamber may be of equal diameter; more preferably, referring to fig. 7 and 8, the inner diameter of the sweat collecting cavity is gradually reduced from bottom to top, and the gradually reduced structure can effectively reduce the volume of the collecting cavity, and accelerate the sweat filling and measuring and analyzing process.
As shown in fig. 9, the skin surface is not absolutely flat, but exhibits a rugged characteristic, and when the surface of the wearable patch in contact with the skin surface is in a planar state, except at the opening of the sweat collecting cavity, there may be a gap between the skin and the patch due to the rough characteristic of the skin, thereby causing the different collecting cavities to communicate with each other, so that sweat collected in a specific collecting cavity may originate from an area outside the collecting cavity, thereby affecting the accuracy of measurement results.
In order to avoid the interconnection of the different collecting cavities, referring to fig. 10 and 11, a circle of protrusions 400 are respectively disposed on the bottom surface (i.e. the surface contacting with the skin) of the wearable patch at the periphery of the bottom opening of each sweat collecting cavity, so that the inner space enclosed by each circle of protrusions 400 and the space between each circle of protrusions 400 form a groove 401, and the groove structure can accommodate sweat discharged from the protruding skin and sweat glands at corresponding positions, thereby isolating the sweat collecting cavities from each other. Since the skin surface relief may be up to more than 100 μm, the height of the protrusions 400 is preferably comparable to or slightly larger than the skin surface relief, such as 100 μm, 150 μm or even more than 200 μm.
Of course, the skin surface is elastic and compressible, and the wearable patch is typically made of a soft material, such as polydimethylsiloxane PDMS, so the raised structures are not necessarily designed to be more rough than the skin surface.
And 4, after the wearable patch is manufactured, the wearable patch is attached to a target skin area to be detected, namely, the sweat collecting cavity only containing a single sweat gland can be realized on the wearable patch with a high probability, and the sweat collecting cavity only containing a single sweat gland on the wearable patch can be identified through an optical sensing system and used for subsequent sweat measurement analysis.
If the optical sensing system does not identify the sweat collecting cavity containing only single sweat gland on the wearable patch, re-fine adjusting the fitting position of the wearable patch on the target skin area, and then identifying the sweat collecting cavity containing only single sweat gland on the wearable patch through the optical sensing system again.
The foregoing has described exemplary embodiments of the invention, it being understood that any simple variations, modifications, or other equivalent arrangements which would not unduly obscure the invention may be made by those skilled in the art without departing from the spirit of the invention.
Claims (10)
1. A method of locking individual sweat glands comprising the steps of:
step 1, shooting an image of a target skin area, identifying sweat glands capable of discharging sweat in the target skin area in the image, and calculating sweat gland density of the target skin area;
step 2, determining the number of sweat collecting cavities on the wearable patch and the opening area of the sweat collecting cavities at the contact skin based on the poisson distribution principle according to the sweat gland density of the target skin area obtained in the step;
step 3, manufacturing the wearable patch according to the quantity of sweat collecting cavities and the opening area of the sweat collecting cavities, which are determined in the step 2, at the position where the sweat collecting cavities contact the skin;
and 4, after the wearable patch is manufactured, the wearable patch is stuck to a target skin area to be detected, so that the sweat collecting cavity only containing a single sweat gland can be realized on the wearable patch with high probability.
2. The method of locking a single sweat gland according to claim 1 wherein: in step 2, a distribution law P of Poisson distribution containing n sweat glands in a single sweat collecting cavity is set n Is the number n of sweat glands actually contained therein and the average sweat gland number contained therein<n>Is a function of:
setting the opening area S of the sweat collecting cavity at the contact position with the skin, and calculating the average number of sweat glands in the single sweat collecting cavity based on the sweat gland density a of the target skin area obtained in the step 2<n>，<n>a.S by applying poisson distribution principle shown in formula (1), calculating probability P of sweat collecting cavity containing n sweat glands n N is 0, 1 or 2, and the probability of 0 sweat glands contained in all N sweat collecting cavities in the set wearable patch is R, namely P 0 N =r, the number of sweat collection chambers required can be calculated; wherein, the probability R that all N sweat collecting cavities contain 0 sweat glands can be set as a minimum probability value; the probability that all sweat collecting cavities do not contain sweat glands will only be the minimum probability value set, wherein the probability of having sweat collecting cavities containing single sweat glands will be extremely large, thereby effectively ensuring that sweat collecting cavities containing only single sweat glands exist on the wearable patch.
3. A device for implementing the method of locking a single sweat gland as claimed in claim 1, characterized in that: the device comprises an optical sensing system and a wearable patch, wherein the wearable patch is provided with a plurality of sweat collecting cavities, the number of the sweat collecting cavities and the opening area of the sweat collecting cavities, which are contacted with skin, are determined according to sweat gland density in a target skin area to be detected and based on the distribution law of Poisson distribution; wherein sweat gland density within the target skin area is measured by an optical sensing system.
4. A device according to claim 3, characterized in that: the optical sensing system comprises an infrared micro-distance camera and an image processor, and is integrally arranged in the cavity.
5. A device according to claim 3, characterized in that: the arrangement of sweat collecting cavities on the wearable patch is not limited and may be rectangular lattice arrangement or random arrangement.
6. A device according to claim 3, characterized in that: the shape of the opening of all sweat collecting cavities on the wearable patch is not limited, but is preferably a circular opening.
7. A device according to claim 3, characterized in that: the thickness of the wearable patch is 10 μm-1mm.
8. A device according to claim 3, characterized in that: the inner diameter of the sweat collecting cavity is of equal diameter.
9. A device according to claim 3, characterized in that: the inner diameter of the sweat collecting cavity is gradually reduced from bottom to top.
10. A device according to claim 3, characterized in that: a circle of bulges are respectively arranged on the periphery of the bottom opening of each sweat collecting cavity on the bottom surface of the wearable patch, so that different sweat collecting cavities are isolated from each other.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310752051.9A CN117017209A (en) | 2023-06-25 | 2023-06-25 | Method and device for locking single sweat gland |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310752051.9A CN117017209A (en) | 2023-06-25 | 2023-06-25 | Method and device for locking single sweat gland |
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| Publication Number | Publication Date |
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| CN117017209A true CN117017209A (en) | 2023-11-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310752051.9A Pending CN117017209A (en) | 2023-06-25 | 2023-06-25 | Method and device for locking single sweat gland |
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| Country | Link |
|---|---|
| CN (1) | CN117017209A (en) |
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2023
- 2023-06-25 CN CN202310752051.9A patent/CN117017209A/en active Pending
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