CN116999679A - Magnetic compatible guide wire for medium therapy in MRI equipment - Google Patents

Magnetic compatible guide wire for medium therapy in MRI equipment Download PDF

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Publication number
CN116999679A
CN116999679A CN202311085633.2A CN202311085633A CN116999679A CN 116999679 A CN116999679 A CN 116999679A CN 202311085633 A CN202311085633 A CN 202311085633A CN 116999679 A CN116999679 A CN 116999679A
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CN
China
Prior art keywords
coating
core wire
guide wire
compatible guide
mri apparatus
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Application number
CN202311085633.2A
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Chinese (zh)
Inventor
许佳润
陈旭东
李明
王文刚
赵善铭
王富玉
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Shenzhen Liankehanwei Medical Technology Co ltd
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Shenzhen Liankehanwei Medical Technology Co ltd
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Priority to CN202311085633.2A priority Critical patent/CN116999679A/en
Publication of CN116999679A publication Critical patent/CN116999679A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046Tracking techniques
    • A61B2034/2051Electromagnetic tracking systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046Tracking techniques
    • A61B2034/2065Tracking using image or pattern recognition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09133Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Robotics (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention discloses a magnetic compatible guide wire for introducing treatment in MRI equipment, which comprises a hand-held part and a first polytetrafluoroethylene coating; one side of the hand-held part is fixedly connected with a head end, a core wire is arranged in the hand-held part, and the core wire is made of metal capable of cutting magnetic force lines; one side of the outer part of the hand-held part is coated with a first polytetrafluoroethylene coating, and one end of the outer part of the core wire is provided with a friction reducing structure; the friction reducing structure comprises a second polytetrafluoroethylene coating, wherein the second polytetrafluoroethylene coating is coated on one side of the outside of the core wire, and a hydrophilic coating is arranged on the other side of the outside of the core wire; the device can be used for MR perspective (real-time guiding operation), the puncture needle artifact has no interference to the target area, and the relationship between the target area and normal tissues can be clearly displayed, so that the MR image can be used for displaying the interventional diagnosis and treatment image in near real time; so that the surgeon can know the position relation between the surgical instrument and the lesion and the important tissue structure at any time, thereby leading the complex operation to be simpler and more visual.

Description

Magnetic compatible guide wire for medium therapy in MRI equipment
Technical Field
The invention relates to the technical field of guide wires, in particular to a magnetic compatible guide wire for treatment in MRI equipment.
Background
MRI, magnetic resonance imaging, is a non-invasive examination, and has become one of the indispensable imaging diagnostic methods in the current medical field; MRI has the advantages of good soft tissue resolution, non-invasive technology, no X-ray radiation damage, etc.
Interventional magnetic resonance (Interventional Magnetic Resonance), which is a new technology developed in recent years, can be used for diagnosing or treating diseases by using a magnetic resonance guiding instrument; as an interventional guidance tool, the magnetic resonance has the advantages incomparable with other imaging methods, has excellent tissue contrast and a spatial resolution reaching the sub-millimeter level, is beneficial to lesion positioning and interventional guidance, and more importantly, has the capabilities of multi-plane and three-dimensional volume reconstruction, and can comprehensively evaluate important anatomical relations between an interventional targeting region and adjacent tissues.
In the interventional operation process, doctors can approach patients at any time, and the development of an open magnet technology and the progress of a rapid imaging technology lead the interventional treatment under the guidance of magnetic resonance to be developed; the open magnetic resonance system has large imaging space, the operation can be performed in and out of the scanning area, and the operation can be scanned and monitored at any time, so that the operation condition can be observed in real time, and the working efficiency is greatly improved.
During MRI examination, implants made of various metal materials can cause serious artifacts in clinical examination, and the accuracy of disease diagnosis is reduced, wherein the artifacts are mainly represented by large low-signal areas at the metal implants or small high-signal areas at the edges and nearby of the metal implants, sometimes the high-signal areas extend backwards and upwards and the areas become smaller, so that adjacent tissues are also severely deformed and distorted; its generation has two reasons: firstly, the magnetic susceptibility of the metal implant is different from that of surrounding tissues, so that the local uniformity of a static magnetic field is destroyed, and the metal implant is a main cause of metal artifact; secondly, when the gradient coil is electrified to start and shut down, the metal implant generates induced current due to the change of the gradient field, which is also called vortex, and the linear relation between the proton nucleus and the gradient field is destroyed to cause irregular deformation of the image; with the increasing popularity of MRI devices, minimally invasive surgery such as tumor treatment with accurate positioning under MRI is becoming more and more mature. Therefore, research and development of novel medical metal materials and devices compatible with MRI has important clinical significance.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a magnetic compatible guide wire for introducing treatment in an MRI device.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
a magnetically compatible guide wire for use in an MRI apparatus for interventional therapy, comprising a handpiece and a first polytetrafluoroethylene coating; a head end is fixedly connected to one side of the handheld part, a core wire is arranged in the handheld part, and the core wire is made of metal capable of cutting magnetic lines of force; one side of the outer part of the handheld part is coated with a first polytetrafluoroethylene coating, and one end of the outer part of the core wire is provided with a friction reducing structure; the friction reducing structure comprises a second polytetrafluoroethylene coating, wherein the second polytetrafluoroethylene coating is coated on one side of the outside of the core wire, and a hydrophilic coating is arranged on the other side of the outside of the core wire.
Preferably, the core wires are integrally formed and sequentially arranged, the core wires are sequentially divided into a pushing section, a gradual change diameter section and a flat section from left to right, the length of the pushing section is 120-2700 mm, and the length of the gradual change diameter section is 150-250 mm.
Preferably, the length of the core wire is 1500-3000 mm.
Preferably, the core wire comprises two metals capable of cutting magnetic lines, and the two metals capable of cutting magnetic lines are mixed according to a certain proportion.
Preferably, the metal capable of cutting magnetic lines may be iron, cobalt, nickel titanium or the like.
Preferably, the hydrophilic coating is a polyvinylpyrrolidone coating or a maleic acid coating, and the hydrophilic coating is coated by dip coating or spray coating.
Preferably, the exterior of the head end is coated with a soft layer.
Preferably, the first polytetrafluoroethylene coating and the second polytetrafluoroethylene coating are both high molecular compounds formed by polymerizing tetrafluoroethylene.
Compared with the prior art, the invention has the beneficial effects that:
the invention designs a magnetic compatible guide wire for medium-into treatment in MRI equipment, which has the advantages that no ionizing radiation is generated, MR perspective (real-time guiding operation) can be performed, puncture needle artifacts are displayed without interference on a target area, three-dimensional image reconstruction is performed, MR image parameters have temperature dependence and in-vivo change can be noninvasively detected, a Proton Resonance Frequency (PRF) method is a current thermometry gold standard, an ablation effect (T2 signal reduction can be used as one of coagulation necrosis marks) is immediately monitored and evaluated, tumor signal change during puck formation and thermal ablation can be monitored in real time, arbitrary section imaging and multi-parameter imaging, multi-contrast imaging, functional imaging, soft tissue resolution and contrast are superior to CT, the relationship between the target area and normal tissue can be clearly displayed, and the MR guiding can avoid nerve and blood vessel damage to the greatest extent; ultra-fast imaging sequences such as gradient echo (GRE), fast small angle excitation (FLASH) imaging, echo Planar Imaging (EPI), single excitation fast spin echo (SSFSE), etc., enable MR images to reach near real-time display of interventional diagnostic images, MRI is a gold standard for noninvasive assessment of cardiovascular structure and function; so that the surgeon can know the position relation between the surgical instrument and the lesion and the important tissue structure at any time, thereby leading the complex operation to be simpler and more visual.
Drawings
FIG. 1 is a schematic diagram of a front cross-sectional structure according to the present invention;
fig. 2 is a schematic diagram of a partial cross-sectional structure of a core wire according to the present invention.
Legend description:
1. a hand-held part; 2. A core wire;
3. a first polytetrafluoroethylene coating; 4. A headend;
5. a hydrophilic coating; 6. And a second polytetrafluoroethylene coating.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the description of the present invention, it should be noted that, directions or positional relationships indicated by terms such as "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., are based on directions or positional relationships shown in the drawings, are merely for convenience of description and simplification of description, and do not indicate or imply that the apparatus or element to be referred to must have a specific direction, be constructed and operated in the specific direction, and thus should not be construed as limiting the present invention; the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance; furthermore, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
Referring to fig. 1 to 2, a magnetically compatible guide wire for use in an MRI apparatus for therapy, comprising a handpiece 1 and a first polytetrafluoroethylene coating 3; one side of the hand-held part 1 is fixedly connected with a head end 4, a core wire 2 is arranged in the hand-held part 1, and the core wire 2 is made of metal capable of cutting magnetic lines of force; one side of the outer part of the hand-held part 1 is coated with a first polytetrafluoroethylene coating 3, and one end of the outer part of the core wire 2 is provided with a friction reducing structure; the friction reducing structure comprises a second polytetrafluoroethylene coating 5, the second polytetrafluoroethylene coating 5 being coated on one side of the outside of the core wire 2, the other side of the outside of the core wire 2 being provided with a hydrophilic coating 4.
The core wires 2 are integrally formed and sequentially arranged, the core wires 2 are sequentially divided into a pushing section, a gradual change diameter section and a flat section from left to right, the length of the pushing section is 120-2700 mm, and the length of the gradual change diameter section is 150-250 mm; the length of the core wire is 1500-3000 mm; through being provided with hydrophilic coating and polytetrafluoroethylene coating, the inside core silk 2 of little seal wire is integrated into one piece and arrange in proper order, and core silk 2 divide into push section, gradual change diameter section and straight section from a left side to the right side in proper order, and the material of carrying the section is stainless steel material, and stainless steel material can make this seal wire have good push performance and supporting property.
The core wire 2 comprises two metals capable of cutting magnetic lines, and the two metals capable of cutting magnetic lines are mixed according to a certain proportion; the metal capable of cutting magnetic lines can be iron, cobalt, nickel titanium and other metals capable of cutting magnetic lines; selecting two metals capable of cutting magnetic lines, and mixing according to a certain proportion to prepare a core wire 2; the two metals with different proportions are selected for mixing, and the mixing proportion of the two metals can be different according to the field intensity of MRI equipment.
The hydrophilic coating 4 is a polyvinylpyrrolidone coating or a maleic acid coating, and the hydrophilic coating 4 is coated by dip coating or spray coating; the hydrophilic coating 4 is normally in the form of a dry film, and is activated when meeting water, so that the hydrophilic coating 4 becomes very lubricious, and the hydrophilic coating 4 not only can lubricate and prevent the cores and 2, but also can enable the core wires 2 to have corrosion resistance.
The outer part of the head end 4 is coated with a soft layer, and both the first polytetrafluoroethylene coating 3 and the second polytetrafluoroethylene coating 5 are high molecular compounds formed by polymerizing tetrafluoroethylene; because the polytetrafluoroethylene coating has excellent chemical stability, corrosion resistance, sealing performance, high lubrication non-viscosity, electrical insulation and good ageing resistance, the polytetrafluoroethylene coating is arranged outside the handheld end 1, so that the chemical stability of the handheld end 1 is enhanced, the handheld end 1 has the non-stick and lubrication effects, and the polytetrafluoroethylene coating is arranged outside the handheld end 1, so that the friction resistance outside the handheld end can be reduced.
The present invention is not limited to the above-mentioned embodiments, and any person skilled in the art, based on the technical solution of the present invention and the inventive concept thereof, can be replaced or changed within the scope of the present invention.

Claims (8)

1. A magnetically compatible guide wire for use in an MRI apparatus for interventional therapy, comprising a handpiece and a first polytetrafluoroethylene coating; the magnetic field generator is characterized in that one side of the handheld part is fixedly connected with a head end, a core wire is arranged in the handheld part, and the core wire is made of metal capable of cutting magnetic force lines; one side of the outer part of the handheld part is coated with a first polytetrafluoroethylene coating, and one end of the outer part of the core wire is provided with a friction reducing structure; the friction reducing structure comprises a second polytetrafluoroethylene coating, wherein the second polytetrafluoroethylene coating is coated on one side of the outside of the core wire, and a hydrophilic coating is arranged on the other side of the outside of the core wire.
2. A magnetically compatible guide wire for use in an MRI apparatus for mediating therapy according to claim 1, wherein: the core wires are integrally formed and sequentially arranged, the core wires are sequentially divided into a pushing section, a gradual change diameter section and a straight section from left to right, the length of the pushing section is 120-2700 mm, and the length of the gradual change diameter section is 150-250 mm.
3. A magnetically compatible guide wire for use in an MRI apparatus for mediating therapy according to claim 2, wherein: the length of the core wire is 1500-3000 mm.
4. A magnetically compatible guide wire for use in an MRI apparatus for interventional therapy according to claim 3, wherein the core wire comprises two magnetic flux cutting metals, the two magnetic flux cutting metals being mixed in a proportion.
5. A magnetically compatible guide wire for use in MRI apparatus for therapy as claimed in claim 4, wherein said magnetic flux cutting metal is selected from the group consisting of iron, cobalt, nickel titanium, and the like.
6. A magnetically compatible guide wire for use in an MRI apparatus for mediating therapy according to claim 1, wherein: the hydrophilic coating is a polyvinylpyrrolidone coating or a maleic acid coating, and is coated by dip coating or spray coating.
7. A magnetically compatible guide wire for use in an MRI apparatus for mediating therapy according to claim 1, wherein: the exterior of the head end is coated with a soft layer.
8. A magnetically compatible guide wire for use in an MRI apparatus for mediating therapy according to claim 1, wherein: and the first polytetrafluoroethylene coating and the second polytetrafluoroethylene coating are high polymer compounds formed by polymerizing tetrafluoroethylene.
CN202311085633.2A 2023-08-25 2023-08-25 Magnetic compatible guide wire for medium therapy in MRI equipment Pending CN116999679A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311085633.2A CN116999679A (en) 2023-08-25 2023-08-25 Magnetic compatible guide wire for medium therapy in MRI equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202311085633.2A CN116999679A (en) 2023-08-25 2023-08-25 Magnetic compatible guide wire for medium therapy in MRI equipment

Publications (1)

Publication Number Publication Date
CN116999679A true CN116999679A (en) 2023-11-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202311085633.2A Pending CN116999679A (en) 2023-08-25 2023-08-25 Magnetic compatible guide wire for medium therapy in MRI equipment

Country Status (1)

Country Link
CN (1) CN116999679A (en)

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