CN116999029A - Method for measuring endometrial peristalsis based on magnetic resonance image - Google Patents
Method for measuring endometrial peristalsis based on magnetic resonance image Download PDFInfo
- Publication number
- CN116999029A CN116999029A CN202310984188.7A CN202310984188A CN116999029A CN 116999029 A CN116999029 A CN 116999029A CN 202310984188 A CN202310984188 A CN 202310984188A CN 116999029 A CN116999029 A CN 116999029A
- Authority
- CN
- China
- Prior art keywords
- endometrial
- magnetic resonance
- peristalsis
- measuring
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002357 endometrial effect Effects 0.000 title claims abstract description 56
- 230000008855 peristalsis Effects 0.000 title claims abstract description 35
- 238000000034 method Methods 0.000 title claims abstract description 28
- 210000004696 endometrium Anatomy 0.000 claims abstract description 21
- 210000004291 uterus Anatomy 0.000 claims abstract description 16
- 238000005259 measurement Methods 0.000 claims abstract description 12
- 238000007405 data analysis Methods 0.000 claims abstract description 6
- 230000002572 peristaltic effect Effects 0.000 claims description 13
- 230000003068 static effect Effects 0.000 claims description 5
- 210000000754 myometrium Anatomy 0.000 claims description 4
- 238000000264 spin echo pulse sequence Methods 0.000 claims description 4
- 210000001835 viscera Anatomy 0.000 claims description 2
- 238000000691 measurement method Methods 0.000 abstract description 4
- 238000010191 image analysis Methods 0.000 abstract description 2
- 230000004899 motility Effects 0.000 abstract description 2
- 238000002595 magnetic resonance imaging Methods 0.000 description 5
- 238000002604 ultrasonography Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 210000001161 mammalian embryo Anatomy 0.000 description 3
- 238000002054 transplantation Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 208000000509 infertility Diseases 0.000 description 2
- 231100000535 infertility Toxicity 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 210000003815 abdominal wall Anatomy 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000032692 embryo implantation Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 210000003692 ilium Anatomy 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4318—Evaluation of the lower reproductive system
- A61B5/4325—Evaluation of the lower reproductive system of the uterine cavities, e.g. uterus, fallopian tubes, ovaries
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- High Energy & Nuclear Physics (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Abstract
The invention relates to the technical field of medical image analysis, in particular to a measurement method of endometrial peristalsis based on a magnetic resonance image. The method specifically comprises the following steps: s1, performing dynamic scanning on the median sagittal plane of the uterus by using magnetic resonance; s2, observing dynamic images obtained by dynamic scanning to obtain the direction and frequency of endometrial peristalsis; s3, decomposing the scanned dynamic image frame by frame, and measuring an endometrium binding band of the interest point to obtain measurement data; and S4, carrying out data analysis according to the measurement data to obtain the amplitude of endometrial peristalsis. The invention indirectly obtains the direction and frequency of the endometrial peristalsis through observing the signal change of the endometrial binding band; and then, the endometrial motility amplitude is indirectly obtained by measuring the endometrial thickness change of the region of interest, and the method is high in insight and operability, low in cost and suitable for clinical popularization and application.
Description
Technical Field
The invention relates to the technical field of medical image analysis, in particular to a measurement method of endometrial peristalsis based on a magnetic resonance image.
Background
In recent years, there have been a significant increase in infertility patients due to various causes such as environmental and pressure effects. Various pregnancy assisting technologies such as embryo transplantation successfully solve the fertility requirements of partial infertility patients, but most patients still fail repeatedly in the embryo transplantation receiving process, and researches show that peristaltic abnormality of endometrial peristalsis is one of factors causing embryo transplantation failure. There are many existing examination methods of endometrial peristalsis, existing ways of detecting endometrial peristalsis are mainly by transvaginal ultrasound, but the section selection and video quality are highly dependent on the level of operators; moreover, the invasive probe is easy to touch the vagina and the cervix, and the change of uterine peristalsis frequency is artificially caused, so that the positive rate of examination is increased.
The detection method, as for example referred to in patent CN113274028A, is invasive, is prone to patient discomfort, and the catheter may irritate the endometrium, adversely affecting embryo implantation, and therefore cannot be used for routine examination prior to implantation. In the CN112704517B, CN114025072a patent, ultrasound is used to detect endometrial peristaltic waves, ultrasound is used as an acoustic image, and there is a significant lack of development of uterus in the case of excessive abdominal wall fat or insufficient bladder filling of the patient, and the above patent does not measure specific values of peristaltic amplitude.
Therefore, how to objectively, accurately and atraumatically measure various parameters of endometrium and reduce the requirements on the conditions of the subject is a technical problem to be solved.
Disclosure of Invention
The invention aims to provide a measurement method of endometrial peristalsis based on a magnetic resonance image, and provides a non-invasive and objective observation method for clinically observing endometrial peristalsis waves. The invention relates to a measurement method based on magnetic resonance images, which solves the problems of inconsistent measurement layers and abnormal endometrial stress peristalsis caused by invasive examination due to human factors.
In order to achieve the aim of the invention, the technical scheme adopted by the invention is as follows: the method for measuring the endometrial peristalsis based on the magnetic resonance image specifically comprises the following steps: s1, performing dynamic scanning on the median sagittal plane of the uterus by using magnetic resonance; s2, observing dynamic images obtained by dynamic scanning to obtain the direction and frequency of endometrial peristalsis; s3, decomposing the scanned dynamic image frame by frame, and measuring an endometrium binding band of the interest point to obtain measurement data; and S4, carrying out data analysis according to the measurement data to obtain the amplitude of endometrial peristalsis.
In a further preferred embodiment of the present invention, in S1, the median sagittal plane of the uterus is obtained by performing MRI flat scanning on the coronal plane and performing T2 cross-sectional weighted image positioning.
Further, in the preferred technical scheme of the present invention, in the step S1, the dynamic scanning means that the magnetic resonance is repeatedly acquired for the same layer of the median sagittal plane of the uterus.
Further as a preferred technical scheme of the invention, in the S2, the dynamic image is a continuous and repeated acquisition of the same layer by adopting a half fourier acquisition single excitation fast spin echo sequence, and the fast imaging is implemented on the moving organ, so as to generate a series of static images of different time periods and time phases in the moving process.
Further as a preferred technical solution of the present invention, the step S3 specifically includes: analyzing each frame of the scanned dynamic image one by one, and marking the juncture of the endometrium of the front wall and the rear wall of the uterus of each frame, namely the union line of the narrowest place of the uterine cavity of the cervical orifice; a straight line is made at the point of interest so as to be perpendicular to the parallel connection line and the myometrium is cut, and the thickness of the endometrial binding band at the point of interest is measured.
Further as a preferable technical scheme of the invention, the dynamic image is a T2 weighted image, and the endometrium combined band is clearly displayed; endometrial binding band the T2 weighted image is a low signal band.
Further as a preferred technical scheme of the invention, in the step S4, the data analysis is to collect all measurement data, and the maximum value and the minimum value of the thickness of each single peristaltic endometrium binding band are subtracted to obtain the peristaltic amplitude of the endometrium.
Compared with the prior art, the method for measuring the endometrial peristalsis based on the magnetic resonance image has the following technical effects:
(1) The method for measuring the endometrial peristalsis parameters acquires 'static' images of different periods (time phases) of a moving organ through repeated acquisition of the magnetic resonance HASTE sequence on the same layer. The method has the advantages of no wound and objectivity, so that the objective record can be carried out on the endometrium peristaltic state, and the influence of invasive detection on the endometrium peristaltic state and the influence of subjective factors of different operators on the data accuracy are solved. And compared with ultrasound, the method has relatively less limitation on the conditions of the testee, and can be widely used in clinic.
(2) The measuring method of the endometrial peristalsis parameter indirectly obtains the direction and the frequency of endometrial peristalsis through observing the signal change of the uterine binding tape; and then, the endometrial motility amplitude is indirectly obtained by measuring the endometrial thickness change of the region of interest, and the method is high in insight and operability, low in cost and suitable for clinical popularization and application.
Drawings
FIG. 1 is a schematic flow chart of a specific implementation of a method for measuring endometrial peristaltic parameters according to an embodiment of the invention;
fig. 2 is a schematic illustration of a measurement of endometrial-binding band thickness as an example of a 1/2 point measurement of the uterine body in accordance with an embodiment of the invention.
Detailed Description
The invention is further explained in the following detailed description with reference to the drawings so that those skilled in the art can more fully understand the invention and can practice it, but the invention is explained below by way of example only and not by way of limitation.
The method for measuring the endometrial peristalsis based on the magnetic resonance image specifically comprises the following steps: s1, performing dynamic scanning on the median sagittal plane of the uterus by using magnetic resonance; s2, observing dynamic images obtained by dynamic scanning to obtain the direction and frequency of endometrial peristalsis; s3, decomposing the scanned dynamic image frame by frame, and measuring an endometrium binding band of the interest point to obtain measurement data; and S4, carrying out data analysis according to the measurement data to obtain the amplitude of endometrial peristalsis.
In S1, the median sagittal plane of the uterus is obtained by pelvic MRI (magnetic resonance imaging) flat scanning coronal plane and cross section T2 weighted image positioning. In S1, dynamic scanning refers to repeated collection of the same layer of the median sagittal plane of the uterus by magnetic resonance. In S2, the dynamic image is a continuous and repeated acquisition of the same layer by adopting a half Fourier acquisition single excitation fast spin echo sequence, and the fast imaging is implemented on the moving viscera, so that the static image of different time periods and time phases in a series of movement processes is generated. S3, the specific steps include: analyzing each frame of the scanned dynamic image one by one, and marking the juncture of the endometrium of the front wall and the rear wall of the uterus of each frame, namely the union line of the narrowest place of the uterine cavity of the cervical orifice; a straight line is made at the point of interest so as to be perpendicular to the parallel connection line and the myometrium is cut, and the thickness of the endometrial binding band at the point of interest is measured. The dynamic image is a T2 weighted image, and the endometrial binding band is clearly displayed; endometrial binding band the T2 weighted image is a low signal band. And S4, analyzing the data to collect all measured data, and subtracting the minimum value from the maximum value of the thickness of the endometrial binding band of each single peristaltic movement to obtain the peristaltic movement amplitude of the endometrium.
In practice, as shown in fig. 1, in one embodiment of the present invention, a siemens avatho 1.5T MRI machine is used, and the method for measuring endometrial peristalsis parameters of the present invention comprises the following steps:
step 1. The examinee needs to empty the bladder and rectum in the first half hour of examination, does not use contrast medium, and adopts Siemens Avanto1.5T MRI scanner to scan by 8-channel body phased array coil. The examiner lies on the back with his legs parallel, and the scan range is horizontal from the upper ilium edge to the lower ischial branch edge.
Step 2, under a calm breathing state, a chemical shift selective fat suppression technology is applied to obtain a pelvic cavity axis position and a coronal position MR T2 fat-pressing image: repetition Time (TR) =6470 ms, echo time (echo time, TE) =83 ms; the layer thickness is 5mm; the field of view (FOV) is 370mm. Chemical shift selective fat suppression technology obtains a pelvic crown MR T2 fat-pressing image: tr=4490 ms; te=83 ms; layer thickness = 5mm; FOV = 270mm.
And 3, positioning the mid-sagittal plane of the uterus by taking the obtained pelvic axial position and coronal position images as references, and then carrying out continuous and repeated acquisition on the same layer by using a half Fourier acquisition single-excitation fast spin echo sequence (TR/TE=2000/81 ms; layer thickness=4 mm; FOV=300 mm) to generate 'static' images in different periods in a series of movement processes, wherein 60 images are obtained in 6 minutes. The endometrial-binding band appears as a low-signal band in the image.
And 4, observing the change of signals of the acquired image endometrial binding bands (low signal bands) to acquire the direction and frequency of endometrial peristalsis.
Step 5, analyzing each frame of the scanned dynamic image one by one, as shown in fig. 2, wherein a transverse line between points B and C is an endometrium line, namely a connecting line between an endometrium junction point of the front and rear walls of the bottom of the uterus and an endocervical opening, a line on the outer side B and C of the endometrium line is a uterine junction belt-endometrium boundary line, and a line on the outer side a and D of the uterine junction belt-endometrium boundary line is a uterine junction belt-myometrium boundary line; making a straight line perpendicular to the endometrial line at 1/2 point of the uterine body to cut the myometrium, AB: posterior uterine wall binding tape, CD: the anterior uterine wall incorporates a band. The thickness of the endometrial-binding band (low signal zone) was measured. The maximum value minus the minimum value of the thickness of the combination band of the endometrium is adopted to obtain the peristaltic amplitude of the endometrium.
While the foregoing is directed to embodiments of the present invention, other and further details of the invention may be devised without departing from the basic scope thereof, and the scope thereof is determined by the claims that follow.
Claims (7)
1. The method for measuring the endometrial peristalsis based on the magnetic resonance image is characterized by comprising the following steps of:
s1, performing dynamic scanning on the median sagittal plane of the uterus by using magnetic resonance;
s2, observing dynamic images obtained by dynamic scanning to obtain the direction and frequency of endometrial peristalsis;
s3, decomposing the scanned dynamic image frame by frame, and measuring an endometrium binding band of the interest point to obtain measurement data;
and S4, carrying out data analysis according to the measurement data to obtain the amplitude of endometrial peristalsis.
2. The method for measuring endometrial peristalsis based on magnetic resonance images according to claim 1, wherein in S1, the mid-sagittal plane of the uterus is located by a pelvic MRI flat coronal plane, cross-section T2 weighted image.
3. The method for measuring endometrial peristalsis based on magnetic resonance images according to claim 2, wherein in S1, dynamic scanning means that magnetic resonance is repeatedly acquired for the same layer of the median sagittal plane of the uterus.
4. The method for measuring endometrial peristalsis based on magnetic resonance images according to claim 3, wherein in S2, the dynamic image is a continuous and repeated acquisition of the same plane by using a half fourier acquisition single-shot fast spin echo sequence, and the moving viscera is rapidly imaged, so as to generate static images of different time periods and time phases in a series of movement processes.
5. The method for measuring endometrial peristalsis based on magnetic resonance images according to claim 4, wherein said step S3 specifically comprises: analyzing each frame of the scanned dynamic image one by one, and marking the juncture of the endometrium of the front wall and the rear wall of the uterus of each frame, namely the union line of the narrowest place of the uterine cavity of the cervical orifice; a straight line is made at the point of interest so as to be perpendicular to the parallel connection line and the myometrium is cut, and the thickness of the endometrial binding band at the point of interest is measured.
6. The method for measuring endometrial peristalsis based on magnetic resonance images according to claim 5, characterized in that the dynamic image is a T2 weighted image, the endometrial binding band is clearly displayed; endometrial binding band the T2 weighted image is a low signal band.
7. The method for measuring endometrial peristalsis based on magnetic resonance images according to claim 6, wherein in S4, the data analysis is to collect all the measured data, and the maximum value and the minimum value of the thickness of each single peristaltic endometrial binding band are subtracted to obtain the peristaltic amplitude of the endometrium.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310984188.7A CN116999029A (en) | 2023-08-07 | 2023-08-07 | Method for measuring endometrial peristalsis based on magnetic resonance image |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310984188.7A CN116999029A (en) | 2023-08-07 | 2023-08-07 | Method for measuring endometrial peristalsis based on magnetic resonance image |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116999029A true CN116999029A (en) | 2023-11-07 |
Family
ID=88566867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310984188.7A Pending CN116999029A (en) | 2023-08-07 | 2023-08-07 | Method for measuring endometrial peristalsis based on magnetic resonance image |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116999029A (en) |
-
2023
- 2023-08-07 CN CN202310984188.7A patent/CN116999029A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7297116B2 (en) | Method and apparatus for imaging the cervix and uterine wall | |
| CN109893146B (en) | Female pelvic floor dysfunction assessment method and system | |
| Griffin et al. | Research applications of ultrasonic imaging in reproductive biology | |
| RU2451487C2 (en) | Diagnosis of urethral obstruction | |
| Tang et al. | Measurement of local pulse wave velocity for carotid artery by using an ultrasound-based method | |
| US20070167818A1 (en) | Device and system for in-vivo measurement of biomechanical properties of internal tissues | |
| Hee et al. | Cervical stiffness evaluated in vivo by endoflip in pregnant women | |
| CN110522473B (en) | Full-automatic examination imaging system of gynaecology and obstetrics | |
| RU2681515C1 (en) | Method of differential diagnosis of cynic formations of pancreas | |
| KR102143381B1 (en) | Ultrasonic image processing apparatus and method | |
| CN111281426B (en) | Ultrasonic imaging and image analysis method for superficial nerves | |
| Kamel et al. | Fetal head descent assessed by transabdominal ultrasound: a prospective observational study | |
| Ginther | Ultrasonic imaging of equine ovarian follicles and corpora lutea | |
| CN116999029A (en) | Method for measuring endometrial peristalsis based on magnetic resonance image | |
| Wang et al. | Perineal ultrasound versus magnetic resonance imaging (MRI) detection for evaluation of pelvic diaphragm in resting state | |
| Kratochwil et al. | Ultrasonic pelvimetry | |
| CN108720870A (en) | A kind of fatty liver detecting system based on ultrasonic attenuation coefficient | |
| CN111202519B (en) | Method and system for detecting hardness of in-vivo thrombus | |
| Watmough et al. | A critical assessment of ultrasonic fetal cephalometry | |
| Henrich et al. | Advantages of and applications for extended field-of-view ultrasound in obstetrics | |
| Varma et al. | Ultrasonic assessment of cervix in “at risk” patients | |
| CN116035538B (en) | Multi-modality imaging system for assessing oxygenation status of tissue, method of operation and use | |
| Ulm et al. | Ultrasound evaluation of fetal spine length between 14 and 24 weeks of gestation | |
| RU2377950C2 (en) | Diagnostic technique for vascular remodelling in arterial hypertension | |
| Casciaro et al. | Quantitative and automatic echographic monitoring of labor progression |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication |