CN116942577A - Multi-effect moisturizing, tightening and soothing skin care composition - Google Patents
Multi-effect moisturizing, tightening and soothing skin care composition Download PDFInfo
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- CN116942577A CN116942577A CN202311067688.0A CN202311067688A CN116942577A CN 116942577 A CN116942577 A CN 116942577A CN 202311067688 A CN202311067688 A CN 202311067688A CN 116942577 A CN116942577 A CN 116942577A
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- sodium hyaluronate
- skin care
- extract
- tightening
- care composition
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- 239000000203 mixture Substances 0.000 title claims abstract description 44
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 42
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 89
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 89
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 89
- 239000000284 extract Substances 0.000 claims abstract description 50
- 235000002168 Tilia europaea Nutrition 0.000 claims abstract description 32
- 240000006909 Tilia x europaea Species 0.000 claims abstract description 32
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims abstract description 31
- 229920002498 Beta-glucan Polymers 0.000 claims abstract description 31
- 150000003384 small molecules Chemical class 0.000 claims abstract description 30
- 229940041514 candida albicans extract Drugs 0.000 claims abstract description 28
- 239000012138 yeast extract Substances 0.000 claims abstract description 28
- AJLNZWYOJAWBCR-OOPVGHQCSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=C)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O AJLNZWYOJAWBCR-OOPVGHQCSA-N 0.000 claims abstract description 27
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims abstract description 27
- 108010087806 Carnosine Proteins 0.000 claims abstract description 27
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical compound NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 claims abstract description 27
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims abstract description 27
- 229940095094 acetyl hexapeptide-8 Drugs 0.000 claims abstract description 27
- 108010006338 acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide Proteins 0.000 claims abstract description 27
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims abstract description 27
- 229940044199 carnosine Drugs 0.000 claims abstract description 27
- 108010013296 Sericins Proteins 0.000 claims abstract description 22
- 239000002904 solvent Substances 0.000 claims description 16
- 239000006286 aqueous extract Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 52
- 230000037303 wrinkles Effects 0.000 abstract description 18
- 238000005562 fading Methods 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 64
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 22
- 230000001153 anti-wrinkle effect Effects 0.000 description 19
- 239000008367 deionised water Substances 0.000 description 13
- 229910021641 deionized water Inorganic materials 0.000 description 13
- 230000001804 emulsifying effect Effects 0.000 description 12
- 208000003351 Melanosis Diseases 0.000 description 10
- 239000002994 raw material Substances 0.000 description 10
- 238000003756 stirring Methods 0.000 description 10
- 239000000126 substance Substances 0.000 description 9
- 238000001816 cooling Methods 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 6
- 238000004140 cleaning Methods 0.000 description 6
- 238000007599 discharging Methods 0.000 description 6
- 239000004744 fabric Substances 0.000 description 6
- 238000001914 filtration Methods 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 238000000265 homogenisation Methods 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 230000002087 whitening effect Effects 0.000 description 5
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 4
- 238000005054 agglomeration Methods 0.000 description 4
- 230000002776 aggregation Effects 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 230000036564 melanin content Effects 0.000 description 4
- MTCFGRXMJLQNBG-UHFFFAOYSA-N serine Chemical compound OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 description 4
- 244000146553 Ceiba pentandra Species 0.000 description 3
- 235000003301 Ceiba pentandra Nutrition 0.000 description 3
- 108010022355 Fibroins Proteins 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 241000628997 Flos Species 0.000 description 2
- 240000002129 Malva sylvestris Species 0.000 description 2
- 235000006770 Malva sylvestris Nutrition 0.000 description 2
- 241001522306 Serinus serinus Species 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 230000009759 skin aging Effects 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 206010014970 Ephelides Diseases 0.000 description 1
- 244000268590 Euryale ferox Species 0.000 description 1
- 235000006487 Euryale ferox Nutrition 0.000 description 1
- 240000000982 Malva neglecta Species 0.000 description 1
- 235000000060 Malva neglecta Nutrition 0.000 description 1
- 244000234609 Portulaca oleracea Species 0.000 description 1
- 235000001855 Portulaca oleracea Nutrition 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- 241000907897 Tilia Species 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- -1 pentapeptide-3 Chemical compound 0.000 description 1
- 229940064064 purslane extract Drugs 0.000 description 1
- 230000037384 skin absorption Effects 0.000 description 1
- 231100000274 skin absorption Toxicity 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 230000037339 smooth wrinkles Effects 0.000 description 1
- 229940063898 tilia extract Drugs 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The application relates to the technical field of skin care products, and particularly discloses a skin care composition with multiple effects of moisturizing, tightening and soothing, which comprises the following components of sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), sodium hyaluronate acetylated, sericin, tilia europaea extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine and oat beta-glucan. The application has the advantages of making the skin care product capable of multiple-effect moisturizing, tightening and relieving and playing a better role in resisting wrinkle and fading spots.
Description
Technical Field
The application relates to the field of skin care products, in particular to a multi-effect moisturizing, tightening and soothing skin care composition.
Background
The skin care product is used for protecting skin, and the skin can be protected by the skin care product, so that the spirit and the image of people can be effectively improved, and the attractiveness is greatly improved.
In addition to basic raw materials, functional raw materials are generally added into the skin care product, so that the skin care product has a directional skin care effect, and the skin aging can cause the phenomena of wrinkling, color spots and the like of the skin along with the aging, so that the image of people is reduced, and in order to improve the problem of skin aging, raw materials with the effects of resisting wrinkles and reducing spots are generally added into the skin care product, so that the effects of resisting wrinkles and reducing spots are expected to be realized.
In practice, it is found that when a plurality of substances with different effects are added to the skin care product at the same time, the effects exerted by the substances with different effects are relatively common, so that only substances with similar effects are usually added to one skin care product to superpose the similar effects so as to obtain a better effect, for example, in order to achieve a better anti-wrinkle effect, raw materials with similar effects such as moisturizing, tightening, relieving and the like are usually combined, so that the problem of wrinkles is relieved in multiple aspects, and the principles of the moisturizing, tightening and relieving substances have similar effects on the skin are matched with each other, so that the better effect can be achieved.
However, to solve the problem of color spots, the principle of efficacy of the corresponding functional substances in the skin is greatly different from the principle of efficacy of moisturizing, tightening and soothing substances on the skin, if whitening, freckle-lightening substances and moisturizing, tightening and soothing substances are compounded, the skin care product can have the effects of resisting wrinkles and lightening spots at the same time, but the effect is relatively general and takes effect slowly, so that the anti-wrinkle product and the freckle-lightening product are produced independently to obtain the higher single effect, the product competitiveness is increased, the consumer wants to obtain the nursing effect of resisting wrinkles and lightening spots at the same time, multiple products are required to be used at the same time, and in order to enable the multiple products to have better effect, the use sequence of the various products is also required to be noted, so that the room for improvement is provided.
Disclosure of Invention
In order to enable the skin care product to play a better anti-wrinkle and freckle-removing effect at the same time, the application provides a multi-effect moisturizing and tightening skin care composition.
The application provides a multi-effect moisturizing, tightening and soothing skin care composition which adopts the following technical scheme:
a multi-effect moisturizing, tightening and soothing skin care composition comprising the following components:
sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), acetylated sodium hyaluronate, sericin, tilia europaea extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine, oat beta-glucan, and solvent.
By adopting the technical scheme, better tightening and anti-wrinkle effects can be achieved through the cooperation of the acetylated sodium hyaluronate, the tripeptide-1, the acetyl hexapeptide-8, the pentapeptide-3 and the carnosine; the effects of moisture preservation and wrinkle resistance can be achieved by matching sodium hyaluronate (medium molecules), sodium hyaluronate (small molecules) and sericin; the Tilia europaea flower extract, the yeast extract and the oat beta-glucan are matched to achieve a good moisturizing and relieving effect, so that the good anti-wrinkle effect is achieved through the matching of various components, meanwhile, when sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), sodium hyaluronate, silk fibroin, tilia europaea flower extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine and oat beta-glucan are compounded, the synergistic effect of the components can promote skin metabolism, and pigment can be discharged pointedly and rapidly, the good anti-wrinkle effect is achieved, the extra raw materials with the whitening effect as main materials are not needed, the conflict among the raw materials is avoided, and the prepared skin care product can play the good anti-wrinkle and freckle-lightening effects at the same time.
Preferably, the mass ratio of the sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), sodium hyaluronate acetylated, sericin, tilia europaea extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine, oat beta-glucan and solvent is 1.5-2.5:5.1-7.6:0.5-1.5:0.6-1.5:0.1-0.5:0.4-2:0.00009-0.001:0.0002-0.001:0.0002-0.001:0.04-0.4:0.0004-0.2:84.5-94.5.
By adopting the technical scheme, the composition has better anti-wrinkle effect, further improves the freckle removing effect, can better and rapidly smooth wrinkles and fade freckles, and has better skin care effect by specifically selecting the mass ratio of sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), acetylated sodium hyaluronate, serin, tilia europaea extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine and oat beta-glucan.
Preferably, the mass ratio of the acetylated sodium hyaluronate, the tripeptide-1, the acetyl hexapeptide-8, the pentapeptide-3 and the carnosine is 1:0.000545:0.0006:0.0006:0.22.
by adopting the technical scheme, the skin tightening effect is better, the anti-wrinkle effect is better, and the skin relaxation can be effectively reduced by specifically selecting the mass ratio of the acetylated sodium hyaluronate, the tripeptide-1, the acetyl hexapeptide-8, the pentapeptide-3 and the carnosine.
Preferably, the mass ratio of the sodium hyaluronate (medium molecule), the sodium hyaluronate (small molecule) and the sericin is 2:6.35:1.05.
by adopting the technical scheme, the moisturizing and wrinkle-resisting effects are better by specifically selecting the mass proportion of the sodium hyaluronate (medium molecule), the sodium hyaluronate (small molecule) and the sericin, so that the skin moisture is more sufficient, and the skin is more elastic and resists wrinkles better.
Preferably, the mass ratio of the tilia europaea extract to the yeast extract to the oat beta-glucan is 0.3:1.2:0.1002.
by adopting the technical scheme, the effects of moisturizing and relieving are better by specifically selecting the mass ratio of the tilia europaea extract, the yeast extract and the oat beta-glucan, and the skin injury can be better repaired and the stimulation can be reduced while the skin is supplemented with water, so that the attack of the stimulation factors on skin cells is reduced, the generation of wrinkles is better reduced, and the anti-wrinkle effect is better.
Preferably, the molecular weight of the sodium hyaluronate (medium molecule) is 200000-400000 daltons.
By adopting the technical scheme, the molecular weight of the sodium hyaluronate (medium molecule) is specifically selected, so that the effect of the sodium hyaluronate (small molecule) is better, and the moisturizing effect is better.
Preferably, the molecular weight of the sodium hyaluronate (small molecule) is 5000-8000 daltons.
By adopting the technical scheme, the molecular weight of the sodium hyaluronate (small molecule) is specifically selected, so that the effect of the sodium hyaluronate (medium molecule) is better, and the moisturizing effect is better.
Preferably, the tilia europaea extract is an aqueous extract.
By adopting the technical scheme, the tilia europaea extract is taken as the water extract, so that the skin absorption effect is better, and the moisturizing and soothing effects are better.
In summary, the application has the following beneficial effects:
1. according to the application, the good tightening and anti-wrinkle effects can be achieved through the cooperation of the acetylated sodium hyaluronate, the tripeptide-1, the acetyl hexapeptide-8, the pentapeptide-3 and the carnosine; the effects of moisture preservation and wrinkle resistance can be achieved by matching sodium hyaluronate (medium molecules), sodium hyaluronate (small molecules) and sericin; the Tilia europaea flower extract, the yeast extract and the oat beta-glucan are matched to achieve a good moisturizing and relieving effect, so that the good anti-wrinkle effect is achieved through the matching of various components, meanwhile, when sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), sodium hyaluronate, silk fibroin, tilia europaea flower extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine and oat beta-glucan are compounded, the synergistic effect of the components can promote skin metabolism, and pigment can be discharged pointedly and rapidly, the good anti-wrinkle effect is achieved, the extra raw materials with the whitening effect as main materials are not needed, the conflict among the raw materials is avoided, and the prepared skin care product can play the good anti-wrinkle and freckle-lightening effects at the same time.
2. According to the application, the composition has better anti-wrinkle effect, and meanwhile, the freckle removing effect is further improved, the wrinkles can be quickly smoothed, the color spots can be desalted and the skin care effect is better by specifically selecting the mass ratio of sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), acetylated sodium hyaluronate, serin, tilia extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine and oat beta-glucan.
Detailed Description
The present application will be described in further detail with reference to examples.
Example 1
A skin care composition with multiple effects of moisturizing and relieving is composed of the following components:
solvent, sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), acetylated sodium hyaluronate, sericin, tilia europaea extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine, oat beta-glucan.
Wherein the solvent is deionized water.
Wherein sodium hyaluronate (medium molecule) is purchased from Shandong Furuida, and the molecular weight is 200000 daltons.
Wherein sodium hyaluronate (small molecule) is purchased from Shandong Furuida, and has molecular weight of 5000 daltons.
Among them, sodium hyaluronate was purchased from switzerland patent Hua Du.
Wherein, the sericin is purchased from Korean RADIANT.
Wherein, tilia europaea flower extract is purchased from Switzerland Li Baode (lipoid), water extract, 10:1 Tilia europaea extract.
Wherein the yeast extract is purchased from Angel yeast.
Wherein, tripeptide-1 is purchased from Dongguan Viqi.
Wherein, acetyl hexapeptide-8 is purchased from Dongguan Viqi.
Wherein, the pentapeptide-3 is purchased from Dongguan Viqi.
Wherein, carnosine is purchased from Dongguan Viqi.
Wherein oat beta-glucan is purchased from guangzhou Zhongkang.
The preparation method of the skin care composition with multiple effects of moisturizing and relieving is as follows:
step 1), cleaning the emulsifying pot and various using equipment.
Step 2), adding 94.5kg of deionized water, 1.5kg of sodium hyaluronate (medium molecules), 5.1kg of sodium hyaluronate (small molecules) and 0.5kg of acetylated sodium hyaluronate into a main emulsifying pot, starting low-speed homogenization (500 r/min), dispersing until no agglomeration exists, starting stirring (60 r/min), heating to 85 ℃, preserving heat for 15min, and then cooling.
Step 3), cooling to 45 ℃, adding 0.6kg of sericin, 0.1kg of tilia europaea extract, 0.4kg of yeast extract, 0.00009kg of tripeptide-1, 0.0002kg of acetyl hexapeptide-8, 0.0002kg of pentapeptide-3, 0.04kg of carnosine and 0.0004kg of oat beta-glucan, stirring for 5min at a rotating speed of 60r/min, and uniformly mixing.
And 4) filtering with 300-mesh filter cloth, and discharging to obtain the multi-effect moisturizing and tightening skin care composition.
Example 2
A skin care composition with multiple effects of moisturizing and relieving is composed of the following components:
solvent, sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), acetylated sodium hyaluronate, sericin, tilia europaea extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine, oat beta-glucan.
Wherein the solvent is deionized water.
Wherein sodium hyaluronate (medium molecule) is purchased from Shandong Furuida, and the molecular weight is 320000 daltons.
Wherein sodium hyaluronate (small molecule) is purchased from Shandong Furuida, and has molecular weight of 7540 daltons.
Among them, sodium hyaluronate was purchased from switzerland patent Hua Du.
Wherein, the sericin is purchased from Korean RADIANT.
Wherein, tilia europaea flower extract is purchased from Switzerland Li Baode (lipoid), water extract, 10:1 Tilia europaea extract.
Wherein the yeast extract is purchased from Angel yeast.
Wherein, tripeptide-1 is purchased from Dongguan Viqi.
Wherein, acetyl hexapeptide-8 is purchased from Dongguan Viqi.
Wherein, the pentapeptide-3 is purchased from Dongguan Viqi.
Wherein, carnosine is purchased from Dongguan Viqi.
Wherein oat beta-glucan is purchased from guangzhou Zhongkang.
The preparation method of the skin care composition with multiple effects of moisturizing and relieving is as follows:
step 1), cleaning the emulsifying pot and various using equipment.
Step 2), 89.5kg of deionized water, 2kg of sodium hyaluronate (medium molecular), 6.35kg of sodium hyaluronate (small molecular) and 1kg of acetylated sodium hyaluronate are added into a main emulsifying pot, low-speed homogenization (500 r/min) is started, the mixture is dispersed until no caking exists, stirring (60 r/min) is started, the temperature is raised to 85 ℃, and the temperature is kept for 15min, and then the temperature is lowered.
Step 3), cooling to 45 ℃, adding 1.05kg of sericin, 0.3kg of tilia europaea extract, 1.2kg of yeast extract, 0.000545kg of tripeptide-1, 0.0006kg of acetyl hexapeptide-8, 0.0006kg of pentapeptide-3, 0.22kg of carnosine and 0.1002kg of oat beta-glucan, stirring for 5min at the rotating speed of 60r/min, and uniformly mixing.
And 4) filtering with 300-mesh filter cloth, and discharging to obtain the multi-effect moisturizing and tightening skin care composition.
Example 3
A skin care composition with multiple effects of moisturizing and relieving is composed of the following components:
solvent, sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), acetylated sodium hyaluronate, sericin, tilia europaea extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine, oat beta-glucan.
Wherein the solvent is deionized water.
Wherein sodium hyaluronate (middle molecule) is purchased from Shandong Furita, and has a molecular weight of 400000 daltons.
Wherein sodium hyaluronate (small molecule) is purchased from Shandong Furuida, and the molecular weight is 8000 daltons.
Among them, sodium hyaluronate was purchased from switzerland patent Hua Du.
Wherein, the sericin is purchased from Korean RADIANT.
Wherein, tilia europaea flower extract is purchased from Switzerland Li Baode (lipoid), water extract, 10:1 Tilia europaea extract.
Wherein the yeast extract is purchased from Angel yeast.
Wherein, tripeptide-1 is purchased from Dongguan Viqi.
Wherein, acetyl hexapeptide-8 is purchased from Dongguan Viqi.
Wherein, the pentapeptide-3 is purchased from Dongguan Viqi.
Wherein, carnosine is purchased from Dongguan Viqi.
Wherein oat beta-glucan is purchased from guangzhou Zhongkang.
The preparation method of the skin care composition with multiple effects of moisturizing and relieving is as follows:
step 1), cleaning the emulsifying pot and various using equipment.
And 2), adding 84.5kg of deionized water, 2.5kg of sodium hyaluronate (medium molecules), 7.6kg of sodium hyaluronate (small molecules) and 1.5kg of acetylated sodium hyaluronate into a main emulsifying pot, starting low-speed homogenization (500 r/min), dispersing until no agglomeration exists, starting stirring (60 r/min), heating to 85 ℃, preserving heat for 15min, and then cooling.
Step 3), cooling to 45 ℃, adding 1.5kg of fibroin, 0.5kg of tilia europaea extract, 2kg of yeast extract, 0.001kg of tripeptide-1, 0.001kg of acetyl hexapeptide-8, 0.001kg of pentapeptide-3, 0.4kg of carnosine and 0.2kg of oat beta-glucan, stirring for 5min at the rotating speed of 60r/min, and uniformly mixing.
And 4) filtering with 300-mesh filter cloth, and discharging to obtain the multi-effect moisturizing and tightening skin care composition.
Comparative example 1
A skin care composition, comprising the following components:
solvent, sodium hyaluronate, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine, oat beta-glucan.
Wherein the solvent is deionized water.
Among them, sodium hyaluronate was purchased from switzerland patent Hua Du.
Wherein, tripeptide-1 is purchased from Dongguan Viqi.
Wherein, acetyl hexapeptide-8 is purchased from Dongguan Viqi.
Wherein, the pentapeptide-3 is purchased from Dongguan Viqi.
Wherein, carnosine is purchased from Dongguan Viqi.
Wherein oat beta-glucan is purchased from guangzhou Zhongkang.
The preparation method of the skin care composition with multiple effects of moisturizing and relieving is as follows:
step 1), cleaning the emulsifying pot and various using equipment.
And 2) adding 89.5kg of deionized water and 1kg of sodium hyaluronate into a main emulsifying pot, starting low-speed homogenization (500 r/min), dispersing until no agglomeration, starting stirring (60 r/min), heating to 85 ℃, preserving heat for 15min, and cooling.
Step 3), cooling to 45 ℃, adding 0.000545kg of tripeptide-1, 0.0006kg of acetyl hexapeptide-8, 0.0006kg of pentapeptide-3, 0.22kg of carnosine and 0.1002kg of oat beta-glucan, stirring for 5min at a rotating speed of 60r/min, and uniformly mixing.
And 4) filtering with 300-mesh filter cloth, and discharging to obtain the multi-effect moisturizing and tightening skin care composition.
Comparative example 2
A skin care composition, comprising the following components:
solvent, sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), and sericin.
Wherein the solvent is deionized water.
Wherein sodium hyaluronate (medium molecule) is purchased from Shandong Furuida, and the molecular weight is 320000 daltons.
Wherein sodium hyaluronate (small molecule) is purchased from Shandong Furuida, and has molecular weight of 7540 daltons.
Wherein, the sericin is purchased from Korean RADIANT.
The preparation method of the skin care composition with multiple effects of moisturizing and relieving is as follows:
step 1), cleaning the emulsifying pot and various using equipment.
Step 2), 89.5kg of deionized water, 2kg of sodium hyaluronate (medium molecules) and 6.35kg of sodium hyaluronate (small molecules) are added into a main emulsifying pot, low-speed homogenization (500 r/min) is started, the mixture is dispersed until no agglomeration exists, stirring (60 r/min) is started, the temperature is raised to 85 ℃, and the temperature is kept for 15min, and then the temperature is lowered.
And 3) cooling to 45 ℃, adding 1.05kg of sericin, stirring for 5min at the rotating speed of 60r/min, and uniformly mixing.
And 4) filtering with 300-mesh filter cloth, and discharging to obtain the multi-effect moisturizing and tightening skin care composition.
Comparative example 3
A skin care composition, comprising the following components:
solvent, tilia europaea extract, yeast extract, oat beta-glucan.
Wherein the solvent is deionized water.
Wherein, tilia europaea flower extract is purchased from Switzerland Li Baode (lipoid), water extract, 10:1 Tilia europaea extract.
Wherein the yeast extract is purchased from Angel yeast.
Wherein oat beta-glucan is purchased from guangzhou Zhongkang.
The preparation method of the skin care composition with multiple effects of moisturizing and relieving is as follows:
step 1), cleaning the emulsifying pot and various using equipment.
Step 2), 89.5kg deionized water, 0.3kg Tilia europaea extract, 1.2kg yeast extract and 0.1002kg oat beta-glucan are added into a main emulsifying pot, and the mixture is stirred for 5min at the rotating speed of 60r/min and uniformly mixed.
And 3) filtering with 300-mesh filter cloth, and discharging to obtain the multi-effect moisturizing and tightening skin care composition.
Comparative example 4
A skin care composition differing from example 2 only in that:
the extract of flos Tiliae Miquelianae is replaced by the extract of flos kapok in equal amount.
Wherein, the kapok extract is from commercial market, water extract, 10:1 kapok proportional extract.
Comparative example 5
A skin care composition differing from example 2 only in that:
the yeast extract was replaced with the mallow extract in equal amounts.
Wherein, the malva sylvestris extract is from the market, the water extract, 10:1 Malva sylvestris extract.
Comparative example 6
A skin care composition differing from example 2 only in that:
herba Portulacae extract is used to replace oat beta-glucan in equal amount.
Wherein, purslane extract is from commercial market, water extract, 10:1 purslane proportional extract.
Experiment 1
The test specimens prepared from the skin care compositions of examples and comparative examples were used once a day before sleeping for 90 days, one group of volunteers was summoned.
Prior to use of the test specimen, skin wrinkles were detected using the PRIMOS rapid three-dimensional imaging system of skin, noted as a pre-use wrinkle measurement, wherein the lower the measurement, the less skin wrinkles.
After 90 days of use of the test specimen, skin wrinkles were again detected using the rapid three-dimensional imaging system PRIMOS of skin, which was noted as a post-use wrinkle measurement, wherein the lower the measurement, the less skin wrinkles.
Prior to use of the test sample, the skin melanin content was measured using the MX18 melanin tester from CK, germany, and recorded as the pre-use melanin content.
After 90 days of use of the test sample, the skin melanin content was again measured using the MX18 melanin tester from CK corporation, germany, and was recorded as the melanin content after use.
The experimental data above were averaged.
The preparation method of the sample to be tested comprises the following steps:
weighing 5g of skin care composition, putting into a container, adding deionized water, shaking uniformly, and fixing the volume to 100ml to obtain a sample to be tested.
The specific test data for experiment 1 are detailed in table 1.
TABLE 1
According to the comparison of the data in the table 1, the compounding of sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), acetylated sodium hyaluronate, sericin, tilia euryale extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine and oat beta-glucan can play a good anti-wrinkle effect and a good melanin removal effect, meanwhile, the effects of smoothing wrinkles and removing color spots are realized, and the effects of eliminating the special whitening effect substances are not required to be added, so that the conflict of raw materials with different effects is avoided, the raw materials with various anti-wrinkle effects are fully utilized, the anti-wrinkle effect is very good, the very remarkable whitening and freckle removal effects can be played, and a consumer can achieve the anti-wrinkle and freckle removal effects with very good effects by using only one product.
The present embodiment is only for explanation of the present application and is not to be construed as limiting the present application, and modifications to the present embodiment, which may not creatively contribute to the present application as required by those skilled in the art after reading the present specification, are all protected by patent laws within the scope of claims of the present application.
Claims (8)
1. A multi-effect moisturizing, tightening and soothing skin care composition characterized by: the composition comprises the following components:
sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), acetylated sodium hyaluronate, sericin, tilia europaea extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine, oat beta-glucan, and solvent.
2. A multi-effect moisturizing, tightening and soothing skin care composition according to claim 1, characterized in that: the mass ratio of the sodium hyaluronate (medium molecule), sodium hyaluronate (small molecule), acetylated sodium hyaluronate, sericin, tilia europaea extract, yeast extract, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, carnosine, oat beta-glucan and solvent is 1.5-2.5:5.1-7.6:0.5-1.5:0.6-1.5:0.1-0.5:0.4-2:0.00009-0.001:0.0002-0.001:0.0002-0.001:0.04-0.4:0.0004-0.2:84.5-94.5.
3. A multi-effect moisturizing, tightening and soothing skin care composition according to claim 2, characterized in that: the mass ratio of the acetylated sodium hyaluronate to the tripeptide-1 to the acetyl hexapeptide-8 to the pentapeptide-3 to the carnosine is 1:0.000545:0.0006:0.0006:0.22.
4. a multi-effect moisturizing, tightening and soothing skin care composition according to claim 2, characterized in that: the mass ratio of the sodium hyaluronate (medium molecule), the sodium hyaluronate (small molecule) and the sericin is 2:6.35:1.05.
5. a multi-effect moisturizing, tightening and soothing skin care composition according to claim 2, characterized in that: the mass ratio of the Tilia europaea extract to the yeast extract to the oat beta-glucan is 0.3:1.2:0.1002.
6. a multi-effect moisturizing, tightening and soothing skin care composition according to claim 1, characterized in that: the molecular weight of the sodium hyaluronate (medium molecule) is 200000-400000 daltons.
7. A multi-effect moisturizing, tightening and soothing skin care composition according to claim 1, characterized in that: the molecular weight of the sodium hyaluronate (small molecule) is 5000-8000 daltons.
8. A multi-effect moisturizing, tightening and soothing skin care composition according to claim 1, characterized in that: the Tilia europaea flower extract is an aqueous extract.
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| KR20170114457A (en) * | 2016-04-05 | 2017-10-16 | 김영미 | Cosmetic Composition for Moisturizing of Skin |
| CN109718194A (en) * | 2018-12-09 | 2019-05-07 | 广州珈源日化用品有限公司 | A kind of yeast extract, oligopeptides -1 and the compact micro- face stoste of acetyl group hexapeptide -1 |
| KR101983217B1 (en) * | 2019-01-03 | 2019-05-28 | 함정율 | Making Method of Cosmetic composition through freeze-drying Preparation having Peptides and sodium hyaluronate |
| CN110731924A (en) * | 2019-07-30 | 2020-01-31 | 浙江养生堂天然药物研究所有限公司 | Enhanced anti-aging cosmetic compositions |
| CN111150681A (en) * | 2020-02-26 | 2020-05-15 | 广州留今科学研究有限公司 | Moisturizing compound containing symbiotic bacteria combined fermentation product, moisturizing essence and preparation method of moisturizing compound |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20170114457A (en) * | 2016-04-05 | 2017-10-16 | 김영미 | Cosmetic Composition for Moisturizing of Skin |
| CN109718194A (en) * | 2018-12-09 | 2019-05-07 | 广州珈源日化用品有限公司 | A kind of yeast extract, oligopeptides -1 and the compact micro- face stoste of acetyl group hexapeptide -1 |
| KR101983217B1 (en) * | 2019-01-03 | 2019-05-28 | 함정율 | Making Method of Cosmetic composition through freeze-drying Preparation having Peptides and sodium hyaluronate |
| CN110731924A (en) * | 2019-07-30 | 2020-01-31 | 浙江养生堂天然药物研究所有限公司 | Enhanced anti-aging cosmetic compositions |
| WO2021017846A1 (en) * | 2019-07-30 | 2021-02-04 | 浙江养生堂天然药物研究所有限公司 | Enhanced anti-aging cosmetic composition |
| CN111150681A (en) * | 2020-02-26 | 2020-05-15 | 广州留今科学研究有限公司 | Moisturizing compound containing symbiotic bacteria combined fermentation product, moisturizing essence and preparation method of moisturizing compound |
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