CN116942550A - Cleaning composition and preparation method and application thereof - Google Patents
Cleaning composition and preparation method and application thereof Download PDFInfo
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- CN116942550A CN116942550A CN202310938216.1A CN202310938216A CN116942550A CN 116942550 A CN116942550 A CN 116942550A CN 202310938216 A CN202310938216 A CN 202310938216A CN 116942550 A CN116942550 A CN 116942550A
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- cleaning composition
- amino acid
- cleaning
- foaming agent
- taurine
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- 238000004140 cleaning Methods 0.000 title claims abstract description 61
- 239000000203 mixture Substances 0.000 title claims abstract description 46
- 238000002360 preparation method Methods 0.000 title abstract description 5
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 30
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 26
- 150000001413 amino acids Chemical class 0.000 claims abstract description 24
- 239000003899 bactericide agent Substances 0.000 claims abstract description 22
- 239000004088 foaming agent Substances 0.000 claims abstract description 18
- 229960003080 taurine Drugs 0.000 claims abstract description 15
- XTJKNGLLPGBHHO-HNNXBMFYSA-N (2s)-5-(diaminomethylideneamino)-2-(dodecanoylamino)pentanoic acid Chemical group CCCCCCCCCCCC(=O)N[C@H](C(O)=O)CCCN=C(N)N XTJKNGLLPGBHHO-HNNXBMFYSA-N 0.000 claims abstract description 12
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000002738 chelating agent Substances 0.000 claims abstract description 7
- 229940024606 amino acid Drugs 0.000 claims description 21
- 235000001014 amino acid Nutrition 0.000 claims description 21
- 229910052708 sodium Inorganic materials 0.000 claims description 16
- 239000011734 sodium Substances 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 13
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 12
- 239000006260 foam Substances 0.000 claims description 12
- 241000195940 Bryophyta Species 0.000 claims description 9
- 235000011929 mousse Nutrition 0.000 claims description 9
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims description 7
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical group [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 7
- 235000013922 glutamic acid Nutrition 0.000 claims description 7
- 239000004220 glutamic acid Substances 0.000 claims description 7
- 229910052700 potassium Inorganic materials 0.000 claims description 7
- 239000011591 potassium Substances 0.000 claims description 7
- 229940061605 tetrasodium glutamate diacetate Drugs 0.000 claims description 7
- UZVUJVFQFNHRSY-OUTKXMMCSA-J tetrasodium;(2s)-2-[bis(carboxylatomethyl)amino]pentanedioate Chemical group [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CC[C@@H](C([O-])=O)N(CC([O-])=O)CC([O-])=O UZVUJVFQFNHRSY-OUTKXMMCSA-J 0.000 claims description 7
- 125000000400 lauroyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 4
- 229940049920 malate Drugs 0.000 claims description 3
- BJEPYKJPYRNKOW-UHFFFAOYSA-N malic acid Chemical compound OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 3
- 125000000291 glutamic acid group Chemical group N[C@@H](CCC(O)=O)C(=O)* 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 239000003002 pH adjusting agent Substances 0.000 claims 2
- 230000007794 irritation Effects 0.000 abstract description 11
- 210000004400 mucous membrane Anatomy 0.000 abstract description 3
- 239000012459 cleaning agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 10
- 239000000047 product Substances 0.000 description 8
- 238000012360 testing method Methods 0.000 description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
- 229920002494 Zein Polymers 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 5
- 239000005019 zein Substances 0.000 description 5
- 229940093612 zein Drugs 0.000 description 5
- 239000007864 aqueous solution Substances 0.000 description 4
- 229940048109 sodium methyl cocoyl taurate Drugs 0.000 description 4
- 239000004094 surface-active agent Substances 0.000 description 4
- 210000003905 vulva Anatomy 0.000 description 4
- 239000003599 detergent Substances 0.000 description 3
- 238000005187 foaming Methods 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 210000002640 perineum Anatomy 0.000 description 3
- 239000000419 plant extract Substances 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 2
- 150000001412 amines Chemical class 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 229960003500 triclosan Drugs 0.000 description 2
- ARXWAVXZIMFYNC-KRWDZBQOSA-N (2s)-5-(diaminomethylideneamino)-2-[dodecanoyl(ethyl)amino]pentanoic acid Chemical compound CCCCCCCCCCCC(=O)N(CC)[C@H](C(O)=O)CCCN=C(N)N ARXWAVXZIMFYNC-KRWDZBQOSA-N 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 229920002413 Polyhexanide Polymers 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 150000001483 arginine derivatives Chemical class 0.000 description 1
- 229960003589 arginine hydrochloride Drugs 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 231100000315 carcinogenic Toxicity 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 229960002152 chlorhexidine acetate Drugs 0.000 description 1
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 description 1
- 229940073507 cocamidopropyl betaine Drugs 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- SFNALCNOMXIBKG-UHFFFAOYSA-N ethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCO SFNALCNOMXIBKG-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 210000002196 fr. b Anatomy 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 229940057950 sodium laureth sulfate Drugs 0.000 description 1
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 1
- CAVXVRQDZKMZDB-UHFFFAOYSA-M sodium;2-[dodecanoyl(methyl)amino]ethanesulfonate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CCS([O-])(=O)=O CAVXVRQDZKMZDB-UHFFFAOYSA-M 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- ICUTUKXCWQYESQ-UHFFFAOYSA-N triclocarban Chemical compound C1=CC(Cl)=CC=C1NC(=O)NC1=CC=C(Cl)C(Cl)=C1 ICUTUKXCWQYESQ-UHFFFAOYSA-N 0.000 description 1
- 229960001325 triclocarban Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to the technical field of cleaning agents, and particularly discloses a cleaning composition, a preparation method and application thereof. The cleaning composition of the present invention comprises: water, primary foaming agent, secondary foaming agent, chelating agent, bactericide, taurine and pH regulator; the bactericide is lauroyl arginine ethyl ester hydrochloride, and the mass ratio of the bactericide to the taurine is 1: (5-6). The invention discovers that taurine is a small molecular amino acid, can reduce the irritation of amino acid type bactericides, and further can be applied to cleaning female private parts related to mucous membrane tissues when the prepared composition contains the amino acid type bactericides.
Description
Technical Field
The invention relates to the technical field of personal care detergents, in particular to a cleaning composition, a preparation method and application thereof.
Background
The perineum of female has special structure, the skin is tender and involves the vulva, and microorganisms are easy to breed. It is therefore desirable that the private parts cleaning products must be mild and have an antibacterial or bacteriostatic effect.
Many private cleaning mousses on the market are compounded by using sodium (or ammonium) laureth sulfate and cocamidopropyl betaine with low content as foaming agents, and although the cleaning force is enough, the cleaning force cannot prove to be mild to the skin or vulva of sensitive parts, and bactericides such as triclosan or triclocarban contained in the cleaning mousse have cancerogenic risks and have been phased out. Other products also use chlorhexidine acetate or polyhexamethylene biguanide hydrochloride as bactericides, but they are chemically synthesized bactericides, and although the sterilizing effect is excellent, the safety of the bactericides is always subject to consumer problems, and meanwhile, the bactericides belong to cationic bactericides and cannot be compounded with high-foam anionic surfactants such as sodium laureth sulfate, so that the foaming performance of the product is poor. In addition, various plant extracts are declared to be used as bacteriostats, but in practice, the bacteriostats are not ideal, and the plant extracts often have color or unpleasant smell, have complex components and seriously affect the stability of the products, so the plant extracts are often used as conceptual additives, the addition amount is not more than 0.2%, and the sterilization effect still needs to be represented by chemical synthesized bactericides, such as triclosan and the like.
Therefore, further research into a mild and effective cleaning and sterilizing product is necessary.
Disclosure of Invention
One of the purposes of the invention is to provide a cleaning product with mild cleaning, bacteriostasis and peculiar smell removal.
In order to achieve the object, the technical scheme of the invention is as follows:
the present invention provides a cleaning composition comprising: water, primary foaming agent, secondary foaming agent, chelating agent, bactericide, taurine and pH regulator; the bactericide is lauroyl arginine ethyl ester hydrochloride, and the mass ratio of the bactericide to the taurine is 1: (5-6), preferably 1: (5.1-5.2).
The research of the invention finds that lauroyl arginine ethyl ester hydrochloride is an amino acid type bactericide, is an arginine derivative, has good antibacterial effect on staphylococcus aureus and candida albicans, but has strong irritation under the effective addition amount, and can not be independently used as an ideal bactericide to be applied to cleaning compositions with mild use effects.
Therefore, the invention is greatly researched, and the prior art discloses a method for reducing the irritation of the formula as a whole by compounding an amino acid type surfactant with milder properties, namely, sodium methyl cocoyl taurate, with other surfactants, so that the addition amount of the other surfactants is reduced. However, when other surfactants in the formulation are milder than sodium methyl cocoyl taurate, the effect of the addition of sodium methyl cocoyl taurate to reduce irritation is lost. And the method cannot reduce the irritation of the amino acid type bactericide, namely lauroyl arginine ethyl ester hydrochloride.
Through further research, the invention discovers that when the taurine which is a small molecular amino acid with a specific proportion is added into the formula, the irritation of the lauroyl arginine ethyl ester hydrochloride is unexpectedly greatly reduced, so that the formula is still moderate in whole under the condition of adding an effective amount, the application of the lauroyl arginine ethyl ester hydrochloride in cleaning tissues which are particularly sensitive to irritation (such as the skin and the vulva of female perineum parts) is suitable, and the application field of the lauroyl arginine ethyl ester hydrochloride is expanded.
The effect of reducing the irritation of the cleaning composition is reduced if the amount of taurine added is reduced, and if the amount is increased, the cost is adversely reduced.
In the cleaning composition of the invention, the primary foaming agent is sodium lauroyl oat amino acid and/or sodium cocoyl malate, and the secondary foaming agent is potassium cocoyl hydrolyzed oat protein; the mass ratio of the primary foaming agent to the secondary foaming agent is (1.2-3): 1, preferably 2.5:1.
The primary and secondary foaming agents used in the present invention are mild to the skin and eyes and are suitable for use in cleansers that may contact mucosal tissue. In addition, the main foaming agent and the secondary foaming agent are properly mixed, so that the cleaning force, the mildness and the foam effect can be simultaneously achieved. If the ratio of the two is 9:1, the product viscosity is low, and the foam is sparse and not dense. When the ratio of the two is 1:1, the viscosity of the product is too high, the foam state is not ideal, the production and the use are inconvenient, and the body feeling is uncomfortable.
In the cleaning composition of the present invention, the chelating agent is tetrasodium glutamate diacetate; the pH regulator is glutamic acid.
The chelating agent used in the invention is amino acid type chelating agent, and can be synergistic and antiseptic.
All active components of the invention are amino acid or derivatives thereof, so that consumers can more easily identify the identity of the amino acid type lotion, and the lotion has no stimulation to human skin and eyes after being integrally matched, has slight stimulation to mucous membrane tissues, and is suitable for daily cleaning of skin and vulva of female perineum parts.
The cleaning composition of the present invention comprises: 2% -3% of lauroyl oat amino acid sodium and/or 2% -3% of cocoyl apple amino acid sodium, 1.8% -2.2% of cocoyl hydrolyzed oat protein potassium, 0.05% -0.08% of tetra sodium glutamate diacetate, 0.3% -0.4% of lauroyl arginine ethyl ester hydrochloride, 1.5% -2% of taurine, 0.1% -0.2% of glutamic acid and the balance of water.
Preferably, the cleaning composition of the present invention comprises: 2.5% of lauroyl oat amino acid sodium and/or 2.5% of cocoyl apple amino acid sodium, 2.0% of cocoyl hydrolyzed oat protein potassium, 0.06-0.062% of tetra sodium glutamate diacetate, 0.35% of lauroyl arginine ethyl ester hydrochloride, 1.8% of taurine, 0.16% of glutamic acid and the balance of water.
The invention combines the cleaning effect, foaming effect, bacteriostasis effect, moisturizing effect and cost of the composition through a reasonable formula.
The composition obtained by the invention has the appearance: clear transparent liquid, no viscosity. Can be matched with a mousse foaming bottle to produce abundant foam; pH (direct assay): 5.0-5.5; stability: 45+/-1 ℃ for 24 hours, and recovering the room temperature to be normal; -5+/-2 ℃ for 24 hours, and recovering the room temperature to be normal.
The invention also provides a method for preparing the cleaning composition, which comprises the steps of mixing all components except the pH regulator and then adding the pH regulator.
The invention further provides an application of the cleaning composition or the cleaning composition prepared by the method in cleaning female private parts.
The invention further provides a female private parts cleaning mousse comprising a mousse foam bottle and a cleaning composition, the cleaning composition being disposed in the mousse foam bottle, the cleaning composition being as described above or prepared by the method described above.
The invention has the advantages that:
the invention provides a cleaning composition based on amino acid or derivatives thereof, which successfully applies an amino acid type bactericide with good antibacterial effect and strong irritation to the cleaning composition which needs a particularly mild effect, and the obtained cleaning composition has mild overall, good cleaning antibacterial effect and abundant foam, and is suitable for cleaning private parts of women.
Detailed Description
Preferred embodiments of the present invention will be described in detail below with reference to examples. It is to be understood that the following examples are given for illustrative purposes only and are not intended to limit the scope of the present invention. Various modifications and alterations of this invention may be made by those skilled in the art without departing from the spirit and scope of this invention.
The experimental methods used in the following examples are conventional methods unless otherwise specified. The materials, reagents and the like used in the examples below, unless otherwise indicated, are all those available commercially or may be prepared by methods conventional in the art.
The sodium lauroyl oat amino acid used in the specific embodiment part of the invention is 20% sodium lauroyl oat amino acid aqueous solution, 20% sodium cocoyl malate aqueous solution, 30% potassium cocoyl hydrolyzed oat protein aqueous solution, 47% tetra sodium glutamate diacetate aqueous solution, and 20% ethyl lauroyl arginine hydrochloride.
Examples 1 to 3
This example provides cleaning compositions, with the following materials in mass percent as shown in table 1.
TABLE 1
The preparation method comprises the following steps:
at normal temperature, adding metering water into a stirring kettle, adding No. 1-6 raw materials according to the sequence of the raw materials in the formula, stirring at 30-50rpm for 10 minutes, and finally adding the formula amount of glutamic acid to adjust the pH value, and filtering and discharging.
Comparative example 1
This comparative example provides a cleaning composition having a formulation substantially the same as example 1, except that sodium methyl cocoyl taurate was used in place of taurine in the same amount.
Comparative example 2
This comparative example provides a cleaning composition having a formulation substantially the same as example 1, except that sodium methyl lauroyl taurate was used in place of taurine in the same amount.
Experimental example
This experimental example tests the performance of the cleaning compositions prepared in the above examples and comparative examples. The method comprises the following steps:
1. toxicology and bacteriostasis test: reference is made to the method described in the 2002 edition of the disinfection specification.
2. Irritation test: adopting a zein method, specifically taking 10ml of cleaning composition, diluting one time, dividing the cleaning composition into two parts, adding 0.5g zein into one part, stirring for 2 hours at 25 ℃, then filtering, and measuring the mass fraction of nitrogen of the filtrate by adopting a micro Kjeldahl nitrogen determination method to be A; another cleaning composition without Zein was measured by the same method for nitrogen mass fraction B, a-b=zein value, and the level of Zein value was used to obtain the irritation intensity of the cleaning composition.
3. Foam effect test: 10ml of a standard hard water-formulated 0.1% cleaning composition was added to a 100ml stoppered cylinder, shaken 30 times, and after standing for 1 minute, the foam height was measured.
4. Cleaning force test: referring to the test method of detergency in GB/T1224-2012 liquid detergent for clothing, the test concentration is 0.2%, and the cleaning force on JB-03 sebum dirt cloth is required to be larger than or equal to that of a standard laundry detergent.
The results of each set of tests are shown in Table 2 below.
TABLE 2
While the invention has been described in detail in the foregoing general description and with reference to specific embodiments thereof, it will be apparent to one skilled in the art that modifications and improvements can be made thereto. Accordingly, such modifications or improvements may be made without departing from the spirit of the invention and are intended to be within the scope of the invention as claimed.
Claims (8)
1. A cleaning composition comprising: water, primary foaming agent, secondary foaming agent, chelating agent, bactericide, taurine and pH regulator; the bactericide is lauroyl arginine ethyl ester hydrochloride, and the mass ratio of the bactericide to the taurine is 1: (5-6).
2. The cleaning composition of claim 1, wherein the primary foaming agent is sodium lauroyl oat amino acid and/or sodium cocoyl malate and the secondary foaming agent is potassium cocoyl hydrolyzed oat protein; the mass ratio of the primary foaming agent to the secondary foaming agent is (1.2-3): 1.
3. the cleaning composition of claim 2 wherein the chelating agent is tetrasodium glutamate diacetate; the pH regulator is glutamic acid.
4. A cleaning composition according to any one of claims 1 to 3, comprising: 2% -3% of lauroyl oat amino acid sodium and/or 2% -3% of cocoyl apple amino acid sodium, 1.8% -2.2% of cocoyl hydrolyzed oat protein potassium, 0.05% -0.08% of tetra sodium glutamate diacetate, 0.3% -0.4% of lauroyl arginine ethyl ester hydrochloride, 1.5% -2% of taurine, 0.1% -0.2% of glutamic acid and the balance of water.
5. The cleaning composition of claim 4, comprising: 2.5% of lauroyl oat amino acid sodium and/or 2.5% of cocoyl apple amino acid sodium, 2.0% of cocoyl hydrolyzed oat protein potassium, 0.06-0.062% of tetra sodium glutamate diacetate, 0.35% of lauroyl arginine ethyl ester hydrochloride, 1.8% of taurine, 0.16% of glutamic acid and the balance of water.
6. A process for preparing a cleaning composition according to any one of claims 1 to 5, wherein the pH adjuster is added after mixing the components other than the pH adjuster.
7. Use of a cleaning composition according to any one of claims 1 to 5 or a cleaning composition prepared by a process according to claim 6 for cleaning female private parts.
8. A female private cleaning mousse comprising a mousse foam bottle and a cleaning composition disposed in the mousse foam bottle, the cleaning composition being as claimed in any one of claims 1 to 5 or produced by the method of claim 6.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202310938216.1A CN116942550A (en) | 2023-07-28 | 2023-07-28 | Cleaning composition and preparation method and application thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN202310938216.1A CN116942550A (en) | 2023-07-28 | 2023-07-28 | Cleaning composition and preparation method and application thereof |
Publications (1)
Publication Number | Publication Date |
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CN116942550A true CN116942550A (en) | 2023-10-27 |
Family
ID=88448795
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CN202310938216.1A Pending CN116942550A (en) | 2023-07-28 | 2023-07-28 | Cleaning composition and preparation method and application thereof |
Country Status (1)
Country | Link |
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CN (1) | CN116942550A (en) |
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2023
- 2023-07-28 CN CN202310938216.1A patent/CN116942550A/en active Pending
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