CN1169319A - Filter for blood dialysis - Google Patents
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- CN1169319A CN1169319A CN 96117593 CN96117593A CN1169319A CN 1169319 A CN1169319 A CN 1169319A CN 96117593 CN96117593 CN 96117593 CN 96117593 A CN96117593 A CN 96117593A CN 1169319 A CN1169319 A CN 1169319A
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Abstract
The medical blood-dialysis filter comprises a non-semmetrical-diaphragm hollow tube wide in diameter which is made of high-molecular material and biological film material and a symmetrical-diaphraym hollow tube which is made of other medical high-molecular material and biological film material, which imitates the action of glomerulus and renal corpusele and has no need of using negative pressure. The medical dialysis filter can be used for treating acute renal failure, chronic toxuria resulted from venal failure and poisoning etc..
Description
The present invention relates to a kind of armarium, particularly a kind of novel hemodialysis filter.The present invention is suitable for giving treatment to acute renal failure (ARF), chronic renal failure (CRF), and multiple organ dysfunction syndrome (MOF) companion renal failure, serious fluid retention, medicine, toxic poisoning etc. carry out hemodiafiltration (HDF) treatment.Be more suitable for hemodialysis filter of new generation, use, also can establish one's own system separately as the equipment of hemodiafiltration treatment as its conventional consumable goods as non-negative pressure dialysis-type.
At present, the used dialyser great majority of conventional hemodialysis (CHD) machine (negative pressure dialysis-type haemodialysis control unit) are simple hemodialyzer, as the TX-110 type (Shanghai) of domestic production; Cuprammonium film dialyser (Zhangjiagang); Cellulose acetate film dialyser and polyacrylonitrile film dialyser and filter (Ningbo), polysulfone membrane filter (Ningbo).The kind of external dialyser of producing and filter is more, but is simple dialysis-type hemodialyzer basically.The SPIRAFLO SG PairedFiltration Filters series of products that gondola this company of Bellc (hundred that sections) produces link to each other dialyser with the method for filter with butt joint, this new structure takes another step undoubtedly to improving therapeutic effect.But, this product links to each other dialyser in the mode of butt joint with filtering, following shortcoming is arranged: (1) HEMOFILTER (High Flux ConvectiveSection) and (HEMODIALYZER) Low Flux DiffusiveSection) the relative connection make its volume seem bigger, oversize; (2) every price reaches the many units of 1200-1800, it is applied in certain limit be restricted; (3) must can use under the monitoring of conventional hemo system, price of complete machine meets or exceeds 800,000 yuan (396000.00 main frames+220000.00-630000.00 water treatment machine).For the County Hospital of vast developing country, so the real difficulty of fancy price is born.Purpose of the present invention, a kind of novel hemodialysis filter that designs at above deficiency exactly.This dialysis filter has been drawn the advantage of dialyser and filter, both can be used as the conventional hemodialysis (CHD) treatment, can implement the hemodiafiltration treatment again; Both improve therapeutic effect, reduced the treatment cost again.Be convenient to promote the use of, be China's economise-create import fund in vast developing country.
The present invention is achieved in that the present invention is by polysulfone membrane, the thicker anisotropic membrane hollow fibrous membrane tube (1) in aperture that poly (ether sulfone) film or other macromolecular material and biomembrane material are made, the core of the hollow fibrous membrane tube of formation dialysis filter; In polysulfone membrane, the outer part of poly (ether sulfone) film hollow fibrous membrane tube (1), the thinner symmetric membrane hollow fibrous membrane tube (2) in aperture that other macromolecular material and biomembrane material are made around central part hollow fibrous membrane tube parallel arranged, in polysulfone membrane, the two ends of the thin two kinds of film pipes of symmetric membrane hollow fibrous membrane tube in the aperture that the film pipe that poly (ether sulfone) film anisotropic membrane aperture is thicker and other macromolecular material and biomembrane material are made, adopt adhesive of medical that two kinds of hollow fibrous membrane tubes are bonded together outside pipe, make the mouth of pipe (3a of hollow fibrous membrane tube, 3b) open, in the outside of two-layer hollow fibrous membrane tube, make shell (4) with macromolecular material, on shell (4), two dialysis solution access hole joint (5a are arranged, 5b), at the two ends of shell, the joint (6a that links to each other with arterio-venous catheter that joins with binding agent with Luo Xuan is arranged respectively, 6b), joint (6a, (3a 3b) locates near the hollow-fiber film tube opening in inside 6b), have the silicone rubber seal packing ring (7a, 7b).As Figure 1-3.Can also be polysulfone membrane, the thicker anisotropic membrane hollow fibrous membrane tube (1) in aperture that poly (ether sulfone) film or other macromolecular material are made, mix to be staggered with film pipe (2) that thinner symmetric membrane macromolecular material in aperture and biomembrane material are made, as shown in Figure 2.
The invention is characterized in: 1. feature of the present invention is that hollow fibre hemodialyzer and filter macromolecule member material and the biomembrane material with different quality and aperture combined, by polysulfone membrane, the thicker material in anisotropic membrane tube material that poly (ether sulfone) film or other macromolecule hollow fibrous membrane tube aperture are thicker and biological hollow fibrous membrane tube aperture constitutes the internal layer core (1 of dialysis filter; It in the outside of (1) the outer membrane pipe (2) that constitutes dialysis filter by thinner symmetric membrane macromolecule member material in aperture and biomembrane material; Can also be polysulfone membrane, the thicker anisotropic membrane hollow fibrous membrane tube (1) in aperture that poly (ether sulfone) film or other macromolecular material and biomembrane material are made mixes to be staggered with film pipe (2) that thinner symmetric membrane macromolecular material in aperture and biomembrane material are made.2. the effective area of dialysis filter is 0.3-1.8M2.3. the cross section, two ends of the film pipe (1) of dialysis filter part and film pipe (2) part is in before the capable crosscut, bonds together mutually outside the film pipe with the no-toxicity medical binding agent.4. in the outside of two kinds of film pipes, make shell (4) with medical macromolecular materials, on shell (4), have dialysis solution access hole joint (5a, 5b); Two ends in shell (4), have respectively the joint that is connected with arterio-venous catheter that joins with medical binding agent with Luo Xuan (6a, 6b), joint (6a, inside 6b) is by the one side of hollow-fiber film tube opening, have the silicone rubber seal packing ring (7a, 7b).
Embodiment: 1. directly adopt polysulfone membrane pipe, poly (ether sulfone) film pipe and hemophan membrane pipe or cuprophan membrane pipe or cellulose acetate film pipe; 2. employing adhesive of medical, two kinds of film pipes are bonded together by certain length (area 0.3-1.8M2), and (the anisotropic membrane pipe is at the center, the symmetric membrane pipe in the periphery or the anisotropic membrane pipe mix the back that is staggered together with the symmetric membrane pipe bonding), constitute the core (1) of dialysis filter, the glomerule part of similar natural kidney; 3. take medical macromolecular materials, make the shell (4) of dialysis filter, have on the shell (4) the dialysis solution access hole (5a, 5b); 4. at the two ends of shell (4), respectively with Luo Xuan and medical bonding agent connect the arteriovenous joint (6a, 6b); 5. (6a, internal layer 6b) are near the one side of hollow-fiber film tube opening, and (7a is 7b) with medical bonding agent sealing with the silicone rubber seal packing ring at joint; 6. the gamma ray sterilization is adopted or with packaging spare after the ethylene oxide gas sterilization in packing back; 7. product of the present invention both can use for non-negative pressure dialysis-type hemo system, also can use for negative pressure dialysis-type hemo system, and it is acute also can be used for the bedside hemodialysis filtration treatment separately, chronic kidney hypofunction, uremia; Also can be used for Wearable artificial kidney device treatment acute renal failure, the multiple organ failure, MOF accompanies the patient of renal failure.
Claims (1)
- A kind of medicinal blood dialysis filter, the present invention is by polysulfone membrane, the thicker anisotropic membrane hollow fibrous membrane tube (1) in aperture that poly (ether sulfone) film or other macromolecular material and biomembrane material are made, constitute the core of the hollow fibrous membrane tube of filter for blood dialysis, in polysulfone membrane, the outside of poly (ether sulfone) film hollow fibrous membrane tube (1), the thinner symmetric membrane hollow fibrous membrane tube of making round other macromolecular material and biomembrane material (2) in aperture, in polysulfone membrane, the two ends of poly (ether sulfone) film pipe or other macromolecular material and biomembrane material hollow fibrous membrane tube, adopt adhesive of medical that two kinds of hollow fibrous membrane tubes are bonded together, cut off the two ends stick portion with lathe, make the mouth of pipe (3a of hollow fibrous membrane tube, 3b) open, outside at two-layer hollow fibrous membrane tube, make shell (4) with macromolecular material, dialysis solution access hole joint (5a is arranged on shell (4), 5b), at the two ends of shell, the joint (6a that links to each other with arterio-venous catheter that joins with binding agent with Luo Xuan is arranged respectively, 6b), joint (6a, there is silicone rubber seal packing ring (7a inside 6b) by hollow fibrous membrane tube one side, 7b) and with medical bonding agent handle (6a 6b) joins with shell (4).The invention is characterized in: 1. feature of the present invention is that the used different quality of hollow fibre hemodialyzer and filter and the macromolecule member material and the biomembrane tube material in aperture are combined, by polysulfone membrane, the thicker material in film tube material that poly (ether sulfone) film or other macromolecule hollow fibre anisotropic membrane pore footpath are thicker and biological hollow fibre anisotropic membrane pore footpath constitutes the internal layer core (1) of dialysis filter; It in the outside of (1) skin (2) that constitutes dialysis filter by thinner symmetric membrane macromolecule member material in aperture and biomembrane material.Can also be polysulfone membrane, polyether sulfone anisotropic membrane or other macromolecular material, the thicker hollow fibrous membrane tube made from biological non-symmetric membrane material (1) in aperture mixes to be staggered with film pipe (2) that thinner macromolecular material in aperture and biomembrane material are made.2. effective exchange area of filter for blood dialysis is 0.3-1.8M2.3. the cross section, two ends of the film pipe (1) of filter for blood dialysis part and film pipe (2) part is in before the crosscut, the film pipe is bonded together mutually outside the film pipe with the no-toxicity medical binding agent.4. cut off the film pipe at the two ends of hollow fibrous membrane tube binding part, make the mouth of pipe (3a, 3b) opening of hollow fibrous membrane tube.5 in the outside of two kinds of film pipes, makes shell (4) with macromolecular material, on shell (4), dialysis solution access hole joint (5a is arranged, 5b), the two ends in shell (4) have the blood that is connected with arterio-venous catheter that joins with medical binding agent with Luo Xuan to import and export joint (6a respectively, 6b), blood import and export joint (6a, inside 6b) is by hollow-fiber film tube opening (3a, one side 3b), have the silicone rubber seal packing ring (7a, 7b).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 96117593 CN1101706C (en) | 1996-06-21 | 1996-06-21 | Filter for blood dialysis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 96117593 CN1101706C (en) | 1996-06-21 | 1996-06-21 | Filter for blood dialysis |
Publications (2)
Publication Number | Publication Date |
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CN1169319A true CN1169319A (en) | 1998-01-07 |
CN1101706C CN1101706C (en) | 2003-02-19 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN 96117593 Expired - Fee Related CN1101706C (en) | 1996-06-21 | 1996-06-21 | Filter for blood dialysis |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100518836C (en) * | 2000-10-30 | 2009-07-29 | 尼弗茹斯公司 | Diafiltration method |
CN102078646A (en) * | 2011-01-22 | 2011-06-01 | 江西三鑫医疗器械集团有限公司 | Polyether sulfone hollow fiber blood dialyzer |
CN102240417A (en) * | 2011-07-11 | 2011-11-16 | 薛磊 | Blood filtration and transfusion bag with double layers of filter membranes |
CN101505811B (en) * | 2006-08-24 | 2012-05-23 | 弗雷泽纽斯医疗保健控股有限公司 | Device for removing fluid from blood in a patient |
CN101035862B (en) * | 2004-10-04 | 2012-08-08 | 索维高级聚合物股份有限公司 | High performance shaped articles, methods of making, and uses thereof |
-
1996
- 1996-06-21 CN CN 96117593 patent/CN1101706C/en not_active Expired - Fee Related
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100518836C (en) * | 2000-10-30 | 2009-07-29 | 尼弗茹斯公司 | Diafiltration method |
CN101035862B (en) * | 2004-10-04 | 2012-08-08 | 索维高级聚合物股份有限公司 | High performance shaped articles, methods of making, and uses thereof |
CN101505811B (en) * | 2006-08-24 | 2012-05-23 | 弗雷泽纽斯医疗保健控股有限公司 | Device for removing fluid from blood in a patient |
CN102078646A (en) * | 2011-01-22 | 2011-06-01 | 江西三鑫医疗器械集团有限公司 | Polyether sulfone hollow fiber blood dialyzer |
CN102240417A (en) * | 2011-07-11 | 2011-11-16 | 薛磊 | Blood filtration and transfusion bag with double layers of filter membranes |
CN102240417B (en) * | 2011-07-11 | 2013-12-18 | 薛磊 | Blood filtration and transfusion bag with double layers of filter membranes |
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Publication number | Publication date |
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CN1101706C (en) | 2003-02-19 |
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