CN116850259A - Traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patient - Google Patents

Traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patient Download PDF

Info

Publication number
CN116850259A
CN116850259A CN202310776058.4A CN202310776058A CN116850259A CN 116850259 A CN116850259 A CN 116850259A CN 202310776058 A CN202310776058 A CN 202310776058A CN 116850259 A CN116850259 A CN 116850259A
Authority
CN
China
Prior art keywords
parts
root
chinese medicine
traditional chinese
medicine composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202310776058.4A
Other languages
Chinese (zh)
Other versions
CN116850259B (en
Inventor
王静
张志强
刘小燕
夏云
骆锦倩
黎瑜
黄琼
廖振毅
陈志潭
丁殊节
朱丽英
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen City Luohu District Chinese Medicine Hospital
Original Assignee
Shenzhen City Luohu District Chinese Medicine Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen City Luohu District Chinese Medicine Hospital filed Critical Shenzhen City Luohu District Chinese Medicine Hospital
Priority to CN202310776058.4A priority Critical patent/CN116850259B/en
Publication of CN116850259A publication Critical patent/CN116850259A/en
Application granted granted Critical
Publication of CN116850259B publication Critical patent/CN116850259B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009Sachets, pouches characterised by the material or function of the envelope
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients, which is prepared from the following raw materials in parts by weight: 5-15 parts of medicinal cyathula root, 9-15 parts of Chinese angelica, 5-15 parts of dried ginger, 10-20 parts of aconite, 5-15 parts of radix clematidis, 10-20 parts of white paeony root, 5-15 parts of eucommia bark, 9-15 parts of phellodendron, 9-15 parts of bighead atractylodes rhizome, 3-9 parts of baical skullcap root, 5-15 parts of cynomorium songaricum, 6-12 parts of Chinese mugwort leaf, 10-20 parts of prepared rehmannia root, 5-15 parts of liquorice piece, 6-12 parts of garden balsam stem, 9-15 parts of lycopodium clavatum, 10-20 parts of Chinese taxillus twig and 5-15 parts of obscured homalomena rhizome. The main recipe is phellodendron bark, which is used for removing fire, and the main recipe is monarch in dosage, so it is intended to take the action of removing fire first. Radix Scutellariae and radix Glycyrrhizae are added for purging pathogenic fire and clearing heat; eucommia ulmoides, achyranthes bidentata and Chinese angelica root, radix Angelicae sinensis are used for replenishing essence and blood to strengthen tendons and bones. White peony root, radix rehmanniae Preparata, and herba Taxilli are used as ministerial drugs for nourishing yin and tonifying blood, nourishing liver and kidney, and herba Taxilli, rhizoma homalomenae, herba Lycopodii, herba Speranskiae Tuberculatae, and strengthening tendons and bones. Herba Cynomorii warms yang and benefits essence, rhizoma Atractylodis Macrocephalae and radix rehmanniae Jiang Jianpi dispel dampness and harmonize middle energizer, and rhizoma Zingiberis and radix Aconiti lateralis Preparata warms middle energizer and promote qi circulation as adjuvant drugs, and folium Artemisiae Argyi warms and dredges channels and collaterals.

Description

Traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patient
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients.
Background
Sarcopenia is a disease caused by muscular atrophy and loss of function. Hemodialysis sarcopenia is a serious complication whose incidence depends on a number of factors including the age, sex, underlying disease, dialysis time, dialysis frequency, dialysis sufficiency, protein intake deficiency, aqueous electrolyte imbalance, chronic inflammatory response, etc. of the patient.
Currently, improvement of sarcopenia in hemodialysis patients mainly depends on exercise and diet. The diet mainly emphasizes increasing the intake of body proteins and amino acids to reduce malnutrition and metabolic abnormalities.
The muscle deficiency syndrome belongs to the flaccidity syndrome in the traditional Chinese medicine, and the pathogenesis of the muscle deficiency syndrome is mainly related to deficiency of qi and blood, weakness of spleen and stomach, deficiency of liver and kidney and the like. The traditional Chinese medicine considers that the occurrence of sarcopenia is related to qi and blood circulation, viscera functions, and channels and collaterals unobstructed and the like of a human body, and the traditional Chinese medicine has the effects of regulating qi and blood, strengthening tendons and bones and dredging channels and collaterals. However, patients with hemodialysis need to control weight, excessive water intake may be caused by oral administration of traditional Chinese medicines, which causes risk of hyperkalemia and the like, and external treatment of traditional Chinese medicines is adopted to better reduce muscle attenuation by matching with resistance exercise.
Accordingly, there is still a need in the art for further improvements and enhancements.
Disclosure of Invention
In view of the defects of the prior art, the invention aims to provide a traditional Chinese medicine composition for treating muscle decay of hemodialysis patients, which is simple and convenient to prepare, low in cost and remarkable in external treatment effect.
To achieve the purpose, the invention adopts the following technical scheme:
in a first aspect, a traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients is prepared from the following raw materials in parts by weight:
5-15 parts of medicinal cyathula root, 9-15 parts of Chinese angelica, 5-15 parts of dried ginger, 10-20 parts of aconite, 5-15 parts of radix clematidis, 10-20 parts of white paeony root, 5-15 parts of eucommia bark, 9-15 parts of phellodendron, 9-15 parts of bighead atractylodes rhizome, 3-9 parts of baical skullcap root, 5-15 parts of cynomorium songaricum, 6-12 parts of Chinese mugwort leaf, 10-20 parts of prepared rehmannia root, 5-15 parts of liquorice piece, 6-12 parts of garden balsam stem, 9-15 parts of lycopodium clavatum, 10-20 parts of Chinese taxillus twig and 5-15 parts of obscured homalomena rhizome.
The following is a preferred technical scheme of the present invention, but not a limitation of the technical scheme provided by the present invention, and the following preferred technical scheme can better achieve and achieve the objects and advantages of the present invention.
As a preferable technical scheme, the traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients is prepared from the following raw materials in parts by weight:
7-13 parts of medicinal cyathula root, 11-13 parts of Chinese angelica, 7-13 parts of dried ginger, 12-18 parts of aconite, 7-17 parts of radix clematidis, 12-18 parts of white peony root, 7-13 parts of eucommia bark, 11-13 parts of amur corktree bark, 11-13 parts of largehead atractylodes rhizome, 5-7 parts of baical skullcap root, 7-13 parts of cynomorium songaricum, 8-9 parts of Chinese mugwort leaf, 12-18 parts of prepared rehmannia root, 7-13 parts of liquoric root tablet, 8-10 parts of garden balsam stem, 11-13 parts of lycopodium clavatum, 12-18 parts of Chinese taxillus twig and 7-13 parts of obscured homalomena rhizome.
As a preferable technical scheme, the traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients is prepared from the following raw materials in parts by weight:
10 parts of medicinal cyathula root, 12 parts of Chinese angelica, 10 parts of dried ginger, 15 parts of accessory piece, 10 parts of clematis root, 15 parts of white paeony root, 10 parts of eucommia bark, 12 parts of phellodendron bark, 12 parts of bighead atractylodes rhizome, 6 parts of baical skullcap root, 10 parts of cynomorium songaricum, 9 parts of Chinese mugwort leaf, 15 parts of prepared rehmannia root, 10 parts of liquorice piece, 9 parts of garden balsam stem, 12 parts of common clubmoss herb, 15 parts of Chinese taxillus herb and 10 parts of obscured homalomena rhizome.
In a second aspect, a traditional Chinese medicine package containing the traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients, wherein the traditional Chinese medicine package further comprises: sea salt, wherein the weight ratio of the sea salt to the traditional Chinese medicine composition is 1:1-5.
As an optimal technical scheme, the traditional Chinese medicine bag is characterized in that the weight ratio of the sea salt to the traditional Chinese medicine composition is 1:1.
As a preferable technical scheme, the traditional Chinese medicine bag is characterized in that the particle size of the sea salt is 1-2mm.
In a third aspect, a method for preparing the above-mentioned traditional Chinese medicine bag includes: pulverizing the Chinese medicinal composition, mixing with sea salt, and packaging into non-woven bag to obtain Chinese medicinal bag.
As a preferable technical scheme, the preparation method of the traditional Chinese medicine bag comprises the steps of pulverizing the traditional Chinese medicine composition, and sieving with a 30-50-mesh sieve.
In a fourth aspect, the use of the said Chinese medicinal composition in the preparation of a medicament for improving muscle attenuation in hemodialysis patients.
In the traditional Chinese medicine composition of the invention:
radix Cyathulae: sweet and slightly bitter in taste, good in property, and capable of restoring liver and kidney meridians, removing blood stasis, dredging meridians, relieving joint pain, inducing diuresis and treating stranguria.
Chinese angelica root: sweet, pungent and warm, enter liver, heart and spleen meridians, tonify blood and activate blood, regulate menstruation and relieve pain, moisten intestines and relieve constipation, and is used for treating blood deficiency and chlorosis.
Dried ginger: pungent and hot. It is effective in invigorating spleen, stomach, kidney, heart and lung channels, warming spleen and stomach, dispelling cold, restoring yang, dredging collaterals, warming lung, and resolving fluid retention.
The attaching piece comprises the following parts: sex taste: da Xin it is toxic and has effects in restoring yang and relieving adverse qi, warming and invigorating spleen and kidney, dispelling cold and relieving pain, and warming yang and expelling cold.
Radix Clematidis: pungent, salty, warm, enter bladder meridian, dispel wind-damp, and unblock meridians.
White peony root: bitter and sour, slightly cold, and has the effects of nourishing liver and spleen channels, nourishing blood, regulating menstruation, astringing yin, stopping sweating, softening liver, relieving pain, and suppressing liver yang.
Eucommia ulmoides: sweet, warm, enter liver and kidney meridians, tonify liver and kidney, strengthen tendons and bones.
Cortex Phellodendri: bitter and cold, enter kidney meridian, bladder meridian and large intestine meridian, clear heat and remove toxicity and dry dampness.
White atractylodes rhizome: bitter and sweet, warm, enter spleen and stomach meridians, invigorate spleen and replenish qi, dry dampness and promote diuresis, and stop sweating.
Radix Scutellariae Baicalensis: bitter, cold, enter lung, gallbladder, spleen, large intestine and small intestine meridians, clear heat and dry dampness, purge fire and detoxify, stop bleeding.
Cynomorium songaricum: sweet and warm. It is effective in invigorating liver, kidney, and large intestine channel, tonifying kidney yang, replenishing essence and blood, and loosening bowel to relieve constipation.
Mugwort leaf: pungent, bitter and warm; has small toxicity, and can enter liver, spleen and kidney meridians, warm meridians to stop bleeding, dispel cold to stop pain; for external use, it can dispel dampness and relieve itching.
Prepared rehmannia root: sweet and slightly warm. It can enter liver and kidney meridians, enrich blood, nourish yin, benefit essence and fill marrow.
Licorice tablet: sweet, it can nourish heart, lung, spleen and stomach meridians, and has the actions of invigorating spleen and replenishing qi, and clearing heat and detoxicating.
Garden balsam stem: pungent and warm nature, good warm property, enter lung and liver meridians, dispel wind and remove dampness, relax tendons and activate blood, dispel stasis and alleviate edema.
Lycopodium clavatum: slightly bitter and pungent, warm, enter liver, spleen and kidney meridians, dispel wind and remove dampness, relax tendons and activate collaterals.
Loranthus mulberry mistletoe: bitter and sweet, pacify, enter liver and kidney meridians, dispel wind-damp, nourish liver and kidney, strengthen tendons and bones.
Homalomena occulta L.var.homalomena L.: bitter and pungent, warm, enter liver and kidney meridians, dispel wind-damp, strengthen tendons and bones.
The main recipe is phellodendron bark, which is used for removing fire, and the main recipe is monarch in dosage, so it is intended to take the action of removing fire first. Radix Scutellariae and radix Glycyrrhizae are added for purging pathogenic fire and clearing heat; eucommia ulmoides, achyranthes bidentata and Chinese angelica root, radix Angelicae sinensis are used for replenishing essence and blood to strengthen tendons and bones. White peony root, radix rehmanniae Preparata, and herba Taxilli are used as ministerial drugs for nourishing yin and tonifying blood, nourishing liver and kidney, and herba Taxilli, rhizoma homalomenae, herba Lycopodii, herba Speranskiae Tuberculatae, and strengthening tendons and bones. Herba Cynomorii warms yang and benefits essence, rhizoma Atractylodis Macrocephalae and radix rehmanniae Jiang Jianpi dispel dampness and harmonize middle energizer, and rhizoma Zingiberis and radix Aconiti lateralis Preparata warms middle energizer and promote qi circulation as adjuvant drugs, and folium Artemisiae Argyi warms and dredges channels and collaterals. The medicines are compatible, so that the fire purging does not hurt yin, the yin nourishing does not stagnate, the yang middle energizer is required to nourish yin, and both the symptoms and root causes are treated.
The beneficial effects are that: compared with the prior art, the invention is a traditional Chinese medicine for tonifying liver and kidney and strengthening tendons, and is characterized by aiming at chronic kidney disease muscular atrophy and osteoporosis liver and kidney deficiency. The combination of damp-heat clearing and blood activating is suitable for the symptoms of deficiency and excess mixed diseases of chronic kidney disease patients. The recipe has the effects of nourishing kidney, nourishing liver, promoting blood circulation, invigorating qi, relaxing muscles and tendons, relieving pain, preventing sarcopenia and osteoporosis of chronic kidney disease patients, increasing muscle strength and reducing complications.
Detailed Description
The invention provides a traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients, and the invention is further described in detail below in order to make the purposes, technical schemes and effects of the invention clearer and more definite. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
The present invention provides a Chinese medicinal composition for improving muscle attenuation of hemodialysis patients, which is further explained and illustrated by the following specific examples.
Example 1
Taking 5g of medicinal cyathula root, 9g of Chinese angelica, 5g of dried ginger, 10g of accessory piece, 5g of radix clematidis, 10g of white paeony root, 5g of eucommia bark, 9g of amur corktree bark, 9g of largehead atractylodes rhizome, 3g of baical skullcap root, 5g of cynomorium songaricum, 6g of Chinese mugwort leaf, 10g of prepared rehmannia root, 5g of liquoric root tablet, 6g of garden balsam stem, 9g of common clubmoss herb, 10g of Chinese taxillus twig and 5g of obscured homalomena rhizome, pulverizing into powder after mixing, sieving the powder with a 30-mesh sieve to obtain medicinal powder, taking 126g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag.
Example 2
Taking 7g of medicinal cyathula root, 11g of Chinese angelica, 7g of dried ginger, 12g of accessory piece, 7g of Chinese clematis, 12g of white paeony root, 7g of eucommia bark, 11g of amur corktree bark, 11g of largehead atractylodes rhizome, 5g of baical skullcap root, 7g of cynomorium songaricum, 8g of Chinese mugwort leaf, 12g of prepared rehmannia root, 7g of liquoric root tablet, 8g of garden balsam stem, 11g of common clubmoss herb, 12g of Chinese taxillus twig and 7g of obscured homalomena rhizome, pulverizing the mixture into powder, sieving the powder with a 30-mesh sieve to obtain medicinal powder, taking 162g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag.
Example 3
Weighing 10 parts of medicinal cyathula root, 12 parts of Chinese angelica, 10 parts of dried ginger, 15 parts of accessory piece, 10 parts of radix clematidis, 15 parts of white paeony root, 10 parts of eucommia ulmoides, 12 parts of phellodendron, 12 parts of bighead atractylodes rhizome, 6 parts of radix scutellariae, 10 parts of cynomorium songaricum, 9 parts of folium artemisiae argyi, 15 parts of prepared rehmannia root, 10 parts of liquorice piece, 9 parts of garden balsam stem, 12 parts of lycopodium clavatum, 15 parts of Chinese taxillus twig and 10 parts of obscured homalomena rhizome, mixing, pulverizing, sieving the powder with a 30-mesh sieve to obtain medicinal powder, taking 205g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag.
Example 4
Weighing 12 parts of medicinal cyathula root, 12 parts of Chinese angelica, 11 parts of dried ginger, 15 parts of accessory piece, 10 parts of radix clematidis, 15 parts of white paeony root, 10 parts of eucommia bark, 13 parts of amur corktree bark, 13 parts of largehead atractylodes rhizome, 6 parts of baical skullcap root, 10 parts of cynomorium songaricum, 9 parts of Chinese mugwort leaf, 17 parts of prepared rehmannia root, 12 parts of liquoric root tablet, 9 parts of garden balsam stem, 12 parts of common clubmoss herb, 16 parts of Chinese taxillus herb and 10 parts of obscured homalomena rhizome, mixing, pulverizing into powder, sieving the powder with a 30-mesh sieve to obtain medicinal powder, taking 208g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag.
Example 5
13g of medicinal cyathula root, 13g of Chinese angelica, 13g of dried ginger, 18g of accessory piece, 13g of clematis root, 18g of white paeony root, 13g of eucommia bark, 13g of amur corktree bark, 13g of largehead atractylodes rhizome, 7g of baical skullcap root, 13g of cynomorium songaricum, 9g of Chinese mugwort leaf, 18g of prepared rehmannia root, 13g of liquoric root tablet, 10g of garden balsam stem, 13g of common clubmoss herb, 18g of Chinese taxillus twig and 13g of obscured homalomena rhizome, grinding into powder after mixing, sieving the powder with a 30-mesh sieve to obtain medicinal powder, taking 243g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag.
Example 6
Taking 14g of medicinal cyathula root, 13g of Chinese angelica, 14g of dried ginger, 18g of accessory piece, 14g of radix clematidis, 18g of white paeony root, 14g of eucommia bark, 14g of amur corktree bark, 13g of largehead atractylodes rhizome, 7g of baical skullcap root, 13g of cynomorium songaricum, 9g of Chinese mugwort leaf, 18g of prepared rehmannia root, 13g of liquoric root tablet, 11g of garden balsam stem, 13g of common clubmoss herb, 18g of Chinese taxillus twig and 13g of obscured homalomena rhizome, pulverizing the mixture into powder, sieving the powder with a 30-mesh sieve to obtain medicinal powder, taking 243g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag.
Example 7
Weighing 12 parts of medicinal cyathula root, 12 parts of Chinese angelica, 11 parts of dried ginger, 15 parts of accessory piece, 10 parts of radix clematidis, 15 parts of white paeony root, 10 parts of eucommia bark, 15 parts of amur corktree bark, 13 parts of largehead atractylodes rhizome, 5 parts of baical skullcap root, 10 parts of cynomorium songaricum, 9 parts of Chinese mugwort leaf, 17 parts of prepared rehmannia root, 15 parts of liquoric root tablet, 9 parts of garden balsam stem, 14 parts of common clubmoss herb, 16 parts of Chinese taxillus herb and 15 parts of obscured homalomena rhizome, mixing, pulverizing into powder, sieving the powder with a 30-mesh sieve to obtain medicinal powder, taking 210g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag. Example 8
Example 8
13 parts of medicinal cyathula root, 12 parts of Chinese angelica, 14 parts of dried ginger, 18 parts of accessory piece, 13 parts of clematis root, 17 parts of white paeony root, 11 parts of eucommia bark, 15 parts of amur corktree bark, 13 parts of largehead atractylodes rhizome, 6 parts of baical skullcap root, 10 parts of cynomorium songaricum, 9 parts of Chinese mugwort leaf, 17 parts of prepared rehmannia root, 15 parts of liquoric root tablet, 9 parts of garden balsam stem, 14 parts of common clubmoss herb, 16 parts of Chinese taxillus herb and 15 parts of obscured homalomena rhizome, grinding into powder after mixing, sieving the powder with a 30-mesh sieve to obtain medicinal powder, taking 213g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag.
Example 9
Taking 14g of medicinal cyathula root, 14g of Chinese angelica, 13g of dried ginger, 20g of accessory piece, 14g of radix clematidis, 20g of white paeony root, 15g of eucommia bark, 15g of amur corktree bark, 15g of largehead atractylodes rhizome, 9g of baical skullcap root, 15g of cynomorium songaricum, 12g of Chinese mugwort leaf, 18g of prepared rehmannia root, 14g of liquoric root tablet, 12g of garden balsam stem, 15g of common clubmoss herb, 20g of Chinese taxillus twig and 15g of obscured homalomena rhizome, pulverizing the mixture into powder, sieving the powder with a 50-mesh sieve to obtain medicinal powder, taking 273g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag.
Example 10
Taking 15g of medicinal cyathula root, 15g of Chinese angelica, 15g of dried ginger, 20g of accessory piece, 15g of radix clematidis, 20g of white paeony root, 15g of eucommia bark, 15g of amur corktree bark, 15g of largehead atractylodes rhizome, 9g of baical skullcap root, 15g of cynomorium songaricum, 12g of Chinese mugwort leaf, 20g of prepared rehmannia root, 15g of liquoric root tablet, 12g of garden balsam stem, 15g of common clubmoss herb, 20g of Chinese taxillus twig and 15g of obscured homalomena rhizome, pulverizing the mixture into powder, sieving the powder with a 50-mesh sieve to obtain medicinal powder, taking 278g of sea salt, uniformly mixing the sea salt and the medicinal powder, and filling the mixture into a non-woven bag.
Treatment cases
Patient 1, men, 60 years old, because of chronic kidney disease, lack physical activity for a long time, lower limb muscle attenuation, walking is laborious, needs family assistance, pale tongue, white fur, deep pulse, dialectical liver and kidney deficiency, and through the external application of a traditional Chinese medicine bag and the cooperation of anti-resistance exercise, the patient can return home and hemodialysis room by oneself after 3 months of exercise.
Patient 2, female 56 years old, hemodialysis room 3 months, with restless leg syndrome, night sleep, dark red tongue, yellow greasy coating, wiry pulse, dialectical damp-heat internal accumulation, blood stasis blocking, through under doctor's guidance, through carrying on the anti-block exercise and external application of the traditional Chinese medicine bag in dialysis, sleep is improved obviously after about 1 month.
Patient 3, female, 70 years old, maintenance hemodialysis for 3 years, unstable walking, calf girth of 25CM, albumin of 33g/L, barthle index of 80 minutes, serial standing test of 2 minutes, 2.44 m walking of 2 minutes, 5 sitting test of 1 minute, diagnosis of sarcopenia, resistance exercise during dialysis combined with traditional Chinese medicine hot-covered external application, exercise after 6 months, re-measurement of calf girth of 27CM, hemoglobin of 38g/L, barthle index of 95 minutes, serial standing test of 3 minutes, 2.44 m walking of 4 minutes, 5 sitting test of 3 minutes, and self-going to and from the hemodialysis room.
Patient 4, female, age 45, maintenance hemodialysis for 2 years, tiredness and weakness, repeated pulmonary infection, pleural effusion, hospitalization every 3 months for up to 20 days. The calf circumference is 30CM, the blood albumin is 33g/L, the Barthle index is 80, the serial standing test is 2, the walking is 2, the sitting test is 1 for 5 times, the muscular deficiency is diagnosed, the chest CT does not prompt the lung infection and the pleural effusion during the period of 8 months after the treatment of the anti-resistance exercise combined with the traditional Chinese medicine heat treatment bag in dialysis. The tiredness feeling is reduced. The calf circumference is 31CM, the blood albumin is 41g/L, the Barthle index is 100 minutes, the series standing test is 3 minutes, the walking is 3 minutes at 2.44 meters, and the sitting test is 4 minutes for 5 times.
It is to be understood that the invention is not limited in its application to the examples described above, but is capable of modification and variation in light of the above teachings by those skilled in the art, and that all such modifications and variations are intended to be included within the scope of the appended claims.

Claims (9)

1. The traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients is characterized by being prepared from the following raw materials in parts by weight:
5-15 parts of medicinal cyathula root, 9-15 parts of Chinese angelica, 5-15 parts of dried ginger, 10-20 parts of aconite, 5-15 parts of radix clematidis, 10-20 parts of white paeony root, 5-15 parts of eucommia bark, 9-15 parts of phellodendron, 9-15 parts of bighead atractylodes rhizome, 3-9 parts of baical skullcap root, 5-15 parts of cynomorium songaricum, 6-12 parts of Chinese mugwort leaf, 10-20 parts of prepared rehmannia root, 5-15 parts of liquorice piece, 6-12 parts of garden balsam stem, 9-15 parts of lycopodium clavatum, 10-20 parts of Chinese taxillus twig and 5-15 parts of obscured homalomena rhizome.
2. The traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients according to claim 1, wherein the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight:
7-13 parts of medicinal cyathula root, 11-13 parts of Chinese angelica, 7-13 parts of dried ginger, 12-18 parts of aconite, 7-13 parts of radix clematidis, 12-18 parts of white peony root, 7-13 parts of eucommia bark, 11-13 parts of amur corktree bark, 11-13 parts of largehead atractylodes rhizome, 5-7 parts of baical skullcap root, 7-13 parts of cynomorium songaricum, 8-9 parts of Chinese mugwort leaf, 12-18 parts of prepared rehmannia root, 7-13 parts of liquoric root tablet, 8-10 parts of garden balsam stem, 11-13 parts of lycopodium clavatum, 12-18 parts of Chinese taxillus twig and 7-13 parts of obscured homalomena rhizome.
3. The traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients according to claim 1, wherein the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight:
10 parts of medicinal cyathula root, 12 parts of Chinese angelica, 10 parts of dried ginger, 15 parts of accessory piece, 10 parts of clematis root, 15 parts of white paeony root, 10 parts of eucommia bark, 12 parts of phellodendron bark, 12 parts of bighead atractylodes rhizome, 6 parts of baical skullcap root, 10 parts of cynomorium songaricum, 9 parts of Chinese mugwort leaf, 15 parts of prepared rehmannia root, 10 parts of liquorice piece, 9 parts of garden balsam stem, 12 parts of common clubmoss herb, 15 parts of Chinese taxillus herb and 10 parts of obscured homalomena rhizome.
4. A kit comprising the traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patients according to any one of claims 1-3, wherein the kit further comprises: sea salt, wherein the weight ratio of the sea salt to the traditional Chinese medicine composition is 1:1-5.
5. The traditional Chinese medicine package according to claim 4, wherein the weight ratio of the sea salt to the traditional Chinese medicine composition is 1:1.
6. The traditional Chinese medicine bag according to claim 4, wherein the particle size of the sea salt is 1-2mm.
7. A method of preparing a pharmaceutical pack according to claim 4, comprising: pulverizing the Chinese medicinal composition, mixing with sea salt, and packaging into non-woven bag to obtain Chinese medicinal bag.
8. The method of claim 6, wherein the powder of the composition is sieved through a 30-50 mesh sieve.
9. Use of a traditional Chinese medicine composition according to any one of claims 1-3 for the preparation of a medicament for improving muscle attenuation in hemodialysis patients.
CN202310776058.4A 2023-06-28 2023-06-28 Traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patient Active CN116850259B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310776058.4A CN116850259B (en) 2023-06-28 2023-06-28 Traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patient

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202310776058.4A CN116850259B (en) 2023-06-28 2023-06-28 Traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patient

Publications (2)

Publication Number Publication Date
CN116850259A true CN116850259A (en) 2023-10-10
CN116850259B CN116850259B (en) 2024-03-19

Family

ID=88224417

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202310776058.4A Active CN116850259B (en) 2023-06-28 2023-06-28 Traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patient

Country Status (1)

Country Link
CN (1) CN116850259B (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1317315A (en) * 2000-04-11 2001-10-17 潘秋兰 Tendon-comfortable analgesic
CN1742994A (en) * 2005-09-29 2006-03-08 夏景祁 Chinese foot-soaking powder
CN101219202A (en) * 2007-01-12 2008-07-16 李芝芹 Soup for strengthening tendon and waist
CN108310191A (en) * 2018-03-28 2018-07-24 李兴云 Promoting blood air circulation and building up bone Chinese medicine composition and its preparation method and application
CN113288939A (en) * 2021-07-15 2021-08-24 深圳市罗湖区中医院 Traditional Chinese medicine composition for protecting kidney and bathing feet and preparation method thereof
CN113384670A (en) * 2021-07-16 2021-09-14 深圳市罗湖区中医院 Kidney-protecting enema prescription for delaying progress of chronic kidney disease

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1317315A (en) * 2000-04-11 2001-10-17 潘秋兰 Tendon-comfortable analgesic
CN1742994A (en) * 2005-09-29 2006-03-08 夏景祁 Chinese foot-soaking powder
CN101219202A (en) * 2007-01-12 2008-07-16 李芝芹 Soup for strengthening tendon and waist
CN108310191A (en) * 2018-03-28 2018-07-24 李兴云 Promoting blood air circulation and building up bone Chinese medicine composition and its preparation method and application
CN113288939A (en) * 2021-07-15 2021-08-24 深圳市罗湖区中医院 Traditional Chinese medicine composition for protecting kidney and bathing feet and preparation method thereof
CN113384670A (en) * 2021-07-16 2021-09-14 深圳市罗湖区中医院 Kidney-protecting enema prescription for delaying progress of chronic kidney disease

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
孙晓芳,等: "孙西庆教授治疗小儿假肥大型肌营养不良的经验", 现代中医药, vol. 35, no. 04, 10 July 2015 (2015-07-10), pages 17 - 18 *
徐文泉,等: "肾着汤加味治疗腰肌纤维织炎228例", 山东中医杂志, no. 01, 20 January 2001 (2001-01-20), pages 26 *
许蔚荣: "痿证验案三则", 江西中医药, no. 02, 21 April 2002 (2002-04-21), pages 29 - 30 *
郭俊含,等: "慢性肾脏病PEW患者IPTH与脂肪和肌肉代谢指标的相关性", 热带医学杂志, vol. 19, no. 05, 28 May 2019 (2019-05-28), pages 579 - 582 *
郭希岩,等: "虎潜丸加减治疗脊髓内出血性痿证", 四川中医, no. 07, 15 July 1989 (1989-07-15), pages 1 *

Also Published As

Publication number Publication date
CN116850259B (en) 2024-03-19

Similar Documents

Publication Publication Date Title
CN101129817B (en) Chinese medicine formulation for treating hypertension and method of producing the same
CN100411649C (en) Traditional Chinese medicine for treating rheumatic and rheumatoid arthritis
CN103920117A (en) Chinese medicinal composition for treating gout and preparation method thereof
CN116850259B (en) Traditional Chinese medicine composition for improving muscle attenuation of hemodialysis patient
CN103611100A (en) Traditional Chinese medicine for treating toothaches
CN112089809A (en) Traditional Chinese medicine composition with spleen invigorating and qi benefiting functions, traditional Chinese medicine plaster and preparation method thereof
CN112316034A (en) Externally-applied traditional Chinese medicine composition for treating chronic pharyngitis as well as preparation method and application thereof
CN105998582A (en) Preparation method of traditional Chinese medicinal composition for treating rheumatoid arthritis
CN111544506A (en) Deer fetus ointment and preparation method thereof
CN104888132A (en) Traditional Chinese medicine composition for treatment of chronic gastritis
CN1054997C (en) Chinese medicine
CN104435962A (en) Pharmaceutical composition for treating dyspeptic diarrhea of piglets and preparation method thereof
CN103656464A (en) Traditional Chinese medicine for treating aplastic anemia
CN1145229A (en) Method for production of cleaning powder for treating internal organs of the body
CN113769046B (en) Traditional Chinese medicine composition for treating intestinal metaplasia, preparation method and application
CN112972564B (en) Traditional Chinese medicine composition for treating osteoporosis and preparation method and application thereof
CN114732879B (en) Pharmaceutical composition for gout and uric acid elevation and preparation method and application thereof
CN110680849B (en) Oral traditional Chinese medicine formula for treating fracture
CN101985027A (en) Chinese herbal medicine for treating liver cirrhosis
CN106955348A (en) Chinese medicine composition and preparation method for treating chronic nephritis
CN108721579A (en) Alleviate the Chinese medicine composition of neck-shoulder pain
CN105456832A (en) Decoction medicine for treating infantile diarrhea and preparation method thereof
CN114886955A (en) Chinese herbal medicine prescription for treating liver disease and preparation method thereof
CN1049599C (en) Medicine for treatment of thromboangiitis obliterans
CN104800703A (en) Traditional Chinese medicine composition for treating irregular menstruation

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant