CN116783209A - 用于cns或肌肉递送的重组腺相关病毒 - Google Patents
用于cns或肌肉递送的重组腺相关病毒 Download PDFInfo
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- CN116783209A CN116783209A CN202180066787.XA CN202180066787A CN116783209A CN 116783209 A CN116783209 A CN 116783209A CN 202180066787 A CN202180066787 A CN 202180066787A CN 116783209 A CN116783209 A CN 116783209A
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- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US202063088988P | 2020-10-07 | 2020-10-07 | |
| US63/088,988 | 2020-10-07 | ||
| PCT/US2021/054058 WO2022076750A2 (en) | 2020-10-07 | 2021-10-07 | Recombinant adeno-associated viruses for cns or muscle delivery |
Publications (1)
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| CN116783209A true CN116783209A (zh) | 2023-09-19 |
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| CN202180066787.XA Pending CN116783209A (zh) | 2020-10-07 | 2021-10-07 | 用于cns或肌肉递送的重组腺相关病毒 |
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| JP (1) | JP2023545384A (https=) |
| KR (1) | KR20230082613A (https=) |
| CN (1) | CN116783209A (https=) |
| AU (1) | AU2021358546A1 (https=) |
| CA (1) | CA3193685A1 (https=) |
| IL (1) | IL301563A (https=) |
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| US20260055144A1 (en) * | 2022-08-24 | 2026-02-26 | Regenxbio Inc. | Recombinant adeno-associated viruses and uses thereof |
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| WO2018119330A2 (en) * | 2016-12-22 | 2018-06-28 | Oregon Health & Science University | Adeno associated viral vectors |
| US11905312B2 (en) * | 2017-02-15 | 2024-02-20 | The University Of North Carolina At Chapel Hill | Methods and compositions for gene transfer across the vasculature |
| WO2020160508A1 (en) * | 2019-01-31 | 2020-08-06 | Oregon Health & Science University | Methods for using transcription-dependent directed evolution of aav capsids |
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2021
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| MX2023003807A (es) | 2023-04-12 |
| EP4225778A2 (en) | 2023-08-16 |
| CA3193685A1 (en) | 2022-04-14 |
| AU2021358546A9 (en) | 2024-02-08 |
| US20230374541A1 (en) | 2023-11-23 |
| IL301563A (en) | 2023-05-01 |
| AU2021358546A1 (en) | 2023-06-08 |
| KR20230082613A (ko) | 2023-06-08 |
| JP2023545384A (ja) | 2023-10-30 |
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