CN116712077B - Vehicle-mounted brain magnetic chart system - Google Patents

Vehicle-mounted brain magnetic chart system Download PDF

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Publication number
CN116712077B
CN116712077B CN202310236465.6A CN202310236465A CN116712077B CN 116712077 B CN116712077 B CN 116712077B CN 202310236465 A CN202310236465 A CN 202310236465A CN 116712077 B CN116712077 B CN 116712077B
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magnetic
data
module
power supply
shielding
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CN116712077A (en
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田鹏飞
盛经纬
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Beijing Kunmai Medical Technology Co ltd
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Beijing Kunmai Medical Technology Co ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B60VEHICLES IN GENERAL
    • B60RVEHICLES, VEHICLE FITTINGS, OR VEHICLE PARTS, NOT OTHERWISE PROVIDED FOR
    • B60R11/00Arrangements for holding or mounting articles, not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/242Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
    • A61B5/245Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02JCIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J9/00Circuit arrangements for emergency or stand-by power supply, e.g. for emergency lighting
    • H02J9/04Circuit arrangements for emergency or stand-by power supply, e.g. for emergency lighting in which the distribution system is disconnected from the normal source and connected to a standby source
    • H02J9/06Circuit arrangements for emergency or stand-by power supply, e.g. for emergency lighting in which the distribution system is disconnected from the normal source and connected to a standby source with automatic change-over, e.g. UPS systems
    • H02J9/062Circuit arrangements for emergency or stand-by power supply, e.g. for emergency lighting in which the distribution system is disconnected from the normal source and connected to a standby source with automatic change-over, e.g. UPS systems for AC powered loads
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02MAPPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
    • H02M1/00Details of apparatus for conversion
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02MAPPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
    • H02M1/00Details of apparatus for conversion
    • H02M1/0003Details of control, feedback or regulation circuits
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02MAPPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
    • H02M1/00Details of apparatus for conversion
    • H02M1/0003Details of control, feedback or regulation circuits
    • H02M1/0016Control circuits providing compensation of output voltage deviations using feedforward of disturbance parameters
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02MAPPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
    • H02M1/00Details of apparatus for conversion
    • H02M1/44Circuits or arrangements for compensating for electromagnetic interference in converters or inverters

Abstract

The invention relates to the field of cranial nerve signal detection. A vehicle-mounted magnetoencephalography system, comprising: the magnetic shield apparatus 100: shielding the magnetic interference signal to make the magnetic interference signal value smaller than or equal to a preset magnetic interference signal threshold value; acquisition management device 300: comprising the following steps: the power module 301: providing an uninterrupted power supply for the vehicle-mounted magnetoencephalography system and filtering electromagnetic interference signals of a power supply; the data acquisition module 304: the brain magnetic signal acquisition device comprises a magnetic detection array for acquiring brain magnetic signals; the data acquisition module 304 is mounted within the magnetic shielding apparatus 100. The vehicle-mounted magnetoencephalography system can be used for magnetoencephalography equipment in a required place, improves the utilization rate and diagnosis and treatment quality of the equipment, and simultaneously provides an automatic gain compensation method suitable for the magnetoencephalography system, and improves signal stability.

Description

Vehicle-mounted brain magnetic chart system
Technical Field
The invention relates to the field of cranial nerve signal detection, in particular to a vehicle-mounted brain magnetic map system.
Background
The Magnetoencephalography (MEG) is a functional brain imaging technology for detecting weak magnetic fields generated by nerve electrical signals, can provide noninvasive detection on brain electrophysiology, and has wide application in clinical and scientific research, including diagnosis and positioning of nervous system diseases such as epilepsy, biomarker research of mental diseases, preoperative brain functional area positioning, brain cognitive neuroscience research and the like. Scanning principles of magnetoencephalography are based on superconducting quantum interferometry (SQUID) technology and on atomic magnetometer (also called atomic magnetometer, OPM) technology.
In the related art, the magnetoencephalography detection scanning systems are all fixed equipment, the equipment cannot be moved, and the equipment can only be installed in a fixed place, so that the magnetoencephalography scanning systems cannot be matched according to requirements, and if the magnetoencephalography system can be moved to a diagnosis and treatment place with requirements, the use efficiency and the medical service level of the magnetoencephalography equipment can be improved.
Patent document CN113160975a discloses a magnetoencephalography system, specifically discloses a fixed installation of a shielding room, the shielding room is not required to be movable, the shielding room is composed of a main body frame, a magnetic shielding layer, a magnetic shielding door, a decoration layer and automatic demagnetizing equipment, and accessory equipment is provided with an air conditioning system interface, an indoor equipment interface, a cable interface and the like. In the scheme, the magnetic shielding room of the magnetoencephalography system is arranged at a fixed place, so that the whole system cannot move according to the requirement.
Disclosure of Invention
The inventor of the present invention has found through a great deal of researches that if a vehicle-mounted magnetoencephalography system is to be provided, the problems of surrounding magnetic interference, electromagnetic interference of an input power supply, etc. need to be solved due to the requirement of the magnetoencephalography detection self principle.
The invention provides a vehicle-mounted magnetoencephalography system, which aims to solve the problem that a magnetoencephalography detection scanning system in the related art can only be installed in a fixed place and cannot be moved to a required place.
In view of the above limitations, the present invention proposes a vehicle-mounted magnetoencephalography system, including:
the magnetic shield apparatus 100: shielding the magnetic interference signal to make the magnetic interference signal value smaller than or equal to a preset magnetic interference signal threshold value;
acquisition management device 300: comprising the following steps:
the power module 301: providing an uninterrupted power supply for the vehicle-mounted magnetoencephalography system and filtering electromagnetic interference signals of a power supply;
the data acquisition module 304: the brain magnetic signal acquisition device comprises a magnetic detection array for acquiring brain magnetic signals;
the data acquisition module 304 is disposed within the magnetic shielding apparatus 100.
Further: further comprises:
damping device 200: fixing the magnetic shielding device 100 in a carriage where the vehicle-mounted magnetoencephalography system is to be installed by the shock absorbing device 200;
the acquisition management apparatus 300 further includes:
noise management module 303: and monitoring and compensating the noise value, and controlling the noise value within a preset noise threshold.
The data transmission module 305: the method comprises the steps of sending acquired brain magnetic signal data to terminal equipment to be connected;
the main control module 302: the main control module 302 is connected with and controls the data acquisition module 304, the noise management module 303 and the data transmission module 305, and acquires and displays the data acquired by the data acquisition module 304 and the noise management module 303.
Further: the magnetic shielding device 100 is formed by a plurality of magnetic shielding cylinders 101 having an opening at one end;
the innermost magnetic shielding cylinder 101 has an inner diameter value W at the position of maximum inner diameter;
in the radial direction of the magnetic shield cylinder 101, a distance Δd between adjacent magnetic shield cylinders 101 i The method meets the following conditions: from the inner magnetic shielding cylinder 101 to the outer magnetic shielding cylinder 101 direction Δd i Gradually increasing; Δd i =(D i+1 -D i ) 2; i represents an i-th shield cylinder 101, i being a natural number;
in the axial direction of the magnetic shield cylinder 101, the intervals Δl between the cylinder openings of the adjacent magnetic shield cylinders 101 are equal, the intervals Δl between the cylinder bottoms of the adjacent magnetic shield cylinders 101 are Δl, and Δl < Δl.
Further: the magnetic shielding barrels 101 are made of materials with magnetic permeability being larger than or equal to a preset magnetic permeability threshold value, the number of the magnetic shielding barrels 101 is larger than or equal to 2, preferably, the magnetic shielding barrels 101 are sleeved with 4-12 layers, and more preferably, the magnetic shielding barrels can be 2, 3, 4, 5, 6, 7, 8, 9, 10 and 11 layers.
Further: an aluminum alloy cylinder or an epoxy cylinder with a shielding layer is added on the outermost layer of the shielding cylinder to play a role in electromagnetic shielding and protection; and/or a layer of epoxy cylinder or other cylinder made of nonmagnetic material is added in the innermost layer to play a role of protection; the above structure can increase the strength of the magnetic shield apparatus 100 and prolong the service life. The inner layer can only be made of epoxy or other non-magnetic material, since the use of metal would destroy the shielding properties of the shielding cylinder.
Further: the shock absorbing device 200 includes:
and (2) a base: the base is fixed at the bottom of the magnetic shielding device 100, a fixing part is arranged on the base, and the base is fixed at the bottom of the carriage through the fixing part, so that the magnetic shielding device 100 is fixed at the bottom of the carriage;
damping layer: the damping layer is an elastic cushion block; the shock absorbing layer is disposed between the base and the magnetic shield apparatus 100.
Further: the fixing part is a lock catch, and the lock catch is arranged on the base; corresponding anchor points are preset at the bottom of the carriage; the lock catch and the anchor point are locked so as to fix the base at the bottom of the carriage; the lock catch is provided with an elastic structure; and/or the fixing part is a bolt and a screw hole, the base and the bottom of the carriage are provided with screw holes, and the base is fixed at the bottom of the carriage by using the bolt;
the elastic cushion block is made of rubber containing nonmagnetic or weak magnetic reinforcing materials.
Further: the power module 301 includes:
isolation filtering unit:
the isolation filtering unit is connected with an external power supply,
the isolation filtering unit includes: a capacitor with a cross-connected input end, a transformer with a core and a cross-connected output end;
the input/output cables of the isolation filter unit use double shielded wires;
the isolation filter unit is arranged in the electrostatic shielding shell;
and the voltage stabilizing unit is used for:
comprising the following steps: the device comprises a voltage regulating module, a sampling circuit, a servo driving module and a control circuit;
the power supply output by the isolation filtering unit is input into the voltage stabilizing unit, and the voltage stabilizing unit controls the servo motor to rotate so as to drive the voltage regulating module to regulate the voltage by comparing the input voltage sample with the output voltage sample, so that a power supply with stable voltage is output;
a power supply unit:
the power supply unit includes a battery; the power supply unit receives the power supply of the stable voltage output by the voltage stabilizing unit and charges the battery with direct current; the power supply unit outputs alternating current to supply power for the vehicle-mounted magnetoencephalography system; the cable of power supply unit output alternating current is double shielded wire.
Further: the noise management module 303 includes:
a data acquisition unit: data acquisition is carried out on the noise signals;
and a processing unit: and respectively calculating the noise value of each channel, calculating the correlation coefficient between the noise value and the noise threshold according to the preset noise threshold of each channel, normalizing the correlation coefficient into a normalized correlation coefficient, and using the normalized correlation coefficient to automatically compensate the channel gain.
Further: the data transmission module 305: comprising the following steps:
a data encryption unit:
encrypting the original data to be transmitted according to a preset encryption algorithm to obtain encrypted data;
identity information generation unit:
calculating an information hash value of the original data by using a preset hash function calculation method as data identity information of the original data, wherein the data identity information is used for verifying the integrity of the received data;
a data transfer unit:
and the network is connected with the terminal equipment, and the encrypted data and the data identity information are sent to the terminal equipment.
Further: the acquisition management apparatus 300 further includes a remote diagnosis module 306, the remote diagnosis module 306 being mounted on the terminal device;
the remote diagnostic module 306 includes:
a data verification unit:
the data verification unit decodes the encrypted data received by the terminal device according to a decryption algorithm corresponding to a preset encryption algorithm to obtain the original data, verifies whether the original data is complete according to the data identity information, and if the original data is incomplete, sends a retransmission request to the data transmission module 305;
remote diagnosis client:
and displaying the original data on the remote diagnosis client according to a preset template for remote diagnosis.
Compared with the related art, the invention has the following advantages:
the vehicle-mounted magnetoencephalography system provided by the invention has the advantages that the magnetic shielding device is arranged, so that the magnetic interference signal can be reduced to the level which does not influence the acquisition of the magnetoencephalography signal, and the interference of the magnetic interference signal on the acquisition of the magnetoencephalography signal due to the magnetic interference signal near the environment where the vehicle-mounted magnetoencephalography system is positioned is avoided. Through setting up the power module that has uninterrupted power source, filtration power electromagnetic interference to thereby can provide voltage stabilization and anti-electromagnetic interference's power input in different environment, thereby guarantee the stability of system and the accuracy of collection data. Therefore, the vehicle-mounted magnetoencephalography system is mounted in the carriage of the vehicle, so that the movable magnetoencephalography system can be realized, and the magnetoencephalography system can be transported to a place with medical requirements, thereby improving the utilization rate of magnetoencephalography equipment, enabling a medical institution which does not have magnetoencephalography detection capability originally to detect the magnetoencephalography, and improving the diagnosis and treatment quality and diagnosis and treatment efficiency of the medical institution.
Drawings
FIG. 1 is an architecture diagram of a magnetoencephalography system according to one embodiment of the present invention;
FIG. 2 is a side view of a magnetic shielding device of the magnetoencephalography system of one embodiment of the present invention;
FIG. 3 is a 1-1 cross-sectional view of a magnetic shield apparatus of the magnetoencephalography system according to one embodiment of the present invention;
FIG. 4 is a schematic block diagram of a power module of the magnetoencephalography system of one embodiment of the present invention;
FIG. 5 is a schematic block diagram of a voltage stabilizing unit of the magnetoencephalography system according to one embodiment of the present invention;
FIG. 6 is an installation diagram of a magnetoencephalography system on a vehicle according to one embodiment of the present invention;
FIG. 7 is a flow chart of a magnetoencephalography system using a real-time transmission mode according to one embodiment of the present invention;
FIG. 8 is a flow chart of a magnetoencephalography system using a backup transmission mode according to one embodiment of the present invention;
FIG. 9 is a 2-2 cross-sectional view of a magnetic shield apparatus of the magnetoencephalography system of one embodiment of the present invention;
fig. 10 is a schematic diagram of a magnetic shielding device of the magnetoencephalography system according to an embodiment of the present invention, which is changed to a magnetic shielding room.
Detailed Description
The present invention will be described in further detail below in order to make the objects, technical solutions and advantages of the present invention more apparent. It is to be understood that the description is only intended to illustrate the invention and is not intended to limit the scope of the invention.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, and the terms used herein in this description of the invention are for the purpose of describing particular embodiments only and are not intended to be limiting of the invention. The characterization means referred to herein are all referred to in the related description of the prior art, and are not described herein in detail.
For a further understanding of the present invention, the present invention will be described in further detail with reference to the following preferred embodiments.
Example 1
As shown in fig. 1, a vehicle-mounted magnetoencephalography system includes:
the magnetic shield apparatus 100: shielding the magnetic interference signal to make the magnetic interference signal value smaller than or equal to a preset magnetic interference signal threshold value;
acquisition management device 300: comprising the following steps:
the power module 301: providing an uninterrupted power supply for the vehicle-mounted magnetoencephalography system and filtering electromagnetic interference signals of a power supply;
the data acquisition module 304: the brain magnetic signal acquisition device comprises a magnetic detection array for acquiring brain magnetic signals;
the data acquisition module 304 is mounted within the magnetic shielding apparatus 100.
The vehicle-mounted magnetoencephalography system is arranged in a carriage of a vehicle, so that the vehicle-mounted magnetoencephalography system can be moved to a required medical place.
Compared with the related art, the vehicle-mounted magnetoencephalography system has the following advantages:
the vehicle-mounted magnetoencephalography system provided by the invention has the advantages that the magnetic shielding device is arranged, so that the magnetic interference signal can be reduced to the level which does not influence the acquisition of the magnetoencephalography signal, and the interference of the magnetic interference signal on the acquisition of the magnetoencephalography signal due to the magnetic interference signal near the environment where the vehicle-mounted magnetoencephalography system is positioned is avoided; through setting up the power module that has uninterrupted power source, filtration power electromagnetic interference to thereby can provide voltage stabilization and anti-electromagnetic interference's power input in different environment, thereby guarantee the stability of system and the accuracy of collection data. Therefore, the vehicle-mounted magnetoencephalography system is mounted in the carriage of the vehicle, so that the movable magnetoencephalography system can be realized, and the magnetoencephalography system can be transported to a place with medical requirements, thereby improving the utilization rate of magnetoencephalography equipment, enabling a medical institution which does not have magnetoencephalography detection capability originally to detect the magnetoencephalography, and improving the diagnosis and treatment quality of the medical institution.
Example 2
As shown in fig. 1, on the basis of example 1,
further: the vehicle-mounted magnetoencephalography system further comprises:
damping device 200: fixing the magnetic shielding device 100 in a carriage where the vehicle-mounted magnetoencephalography system is to be installed by the shock absorbing device 200;
the acquisition management apparatus 300 further includes:
noise management module 303: and monitoring and compensating the noise value, and controlling the noise value within a preset noise threshold.
The data transmission module 305: the method comprises the steps of sending acquired brain magnetic signal data to terminal equipment to be connected;
the main control module 302: the main control module 302 is connected with and controls the data acquisition module 304, the noise management module 303 and the data transmission module 305, and acquires and displays the data acquired by the data acquisition module 304 and the noise management module 303.
The control of the main control module 302 to each module can control the process of detecting the acquisition of the magnetoencephalography, check the noise level value, the transmission condition of the data transmission module, etc. so as to adjust and manage, and the data transmission module 305 can send the data to the terminal to be received, such as the server for storing the data, the client used by the doctor, etc., not limited to the above terminal. The vibration damping device 200 can play a role in fixing and protecting the magnetic shielding device 100, damage caused by impact generated in the driving process is avoided, and meanwhile stability of the magnetic shielding device 100 during the acquisition of a brain magnetic diagram is guaranteed.
Further: the magnetic shielding device 100 is formed by a plurality of magnetic shielding cylinders 101 having an opening at one end;
the innermost magnetic shielding cylinder 101 has an inner diameter value W at the position of maximum inner diameter;
in the radial direction of the magnetic shield cylinder 101, a distance Δd between adjacent magnetic shield cylinders 101 i The method meets the following conditions: from the inner magnetic shielding cylinder 101 to the outer magnetic shielding cylinder 101 direction Δd i Gradually increasing; Δd i =(D i+1 -D i ) 2; i represents an i-th shield cylinder 101, i being a natural number;
as shown in fig. 9, in the axial direction of the magnetic shield cylinder 101, the pitch Δl between the cylinder openings of the adjacent magnetic shield cylinders 101 is equal, and the pitch Δl between the cylinder bottoms of the adjacent magnetic shield cylinders 101 is equal; and Δl < Δl.
The size of the magnetic shield cylinder 101 can be designed according to the above constraint conditions and the allowable space size in the vehicle cabin.
The W is preferably 65-85cm, more preferably 70cm. The vehicle-mounted brain magnetic chart system keeps the aperture size of the largest inner diameter of the magnetic shielding barrel 101 to be 70cm, so that smooth entrance and exit of a subject can be ensured, and the space is saved to the greatest extent. The maximum inner diameter may be set in the width direction of the opening of the magnetic shield tube 101, for example.
Further: the magnetic shielding barrels 101 are made of materials with magnetic permeability being larger than or equal to a preset magnetic permeability threshold value, and the number of the magnetic shielding barrels 101 is larger than or equal to 2. Preferably, the number of the magnetic shielding cylinders 101 is 4 or more; the preset magnetic permeability threshold is 10000, preferably 10 5
The magnetic shielding cylinder 101 is preferably made of permalloy or nickel/cobalt-based amorphous material, and the nominal permeability of permalloy is 10 5 Magnitude. When an external high magnetic field passes through the shielding layer made of high-permeability material, the strength of the magnetic field is reduced by the shielding layer.
Through experimental research, the inventor of the invention discovers that the metal shielding material needs to achieve the magnetic permeability level to achieve the medical shielding effect. Because the magnetoencephalography system does not require external energy to be applied to the human body, but directly collects electromagnetic signals of the human brain through the signal collection system, which are very small, compared with the conventional medical diagnosis device, the intensity of a typical cerebral magnetic field outside the scalp is 10-100 fT (1 ft=10 -15 T) on the order of one part per billion of the earth's magnetic field. In order to ensure that the magnetic shielding device is not interfered by the outside, an environment with a magnetic field lower than a preset value needs to be provided for the signal acquisition of the brain magnetic map, if the magnetic shielding is not good, the signal to noise ratio of the signal is likely to be low, the acquisition effect is likely to be affected, and the acquisition task is likely to be impossible to be carried out if the acquisition is serious.
Since the space of the vehicle is limited, the structure of the magnetic shielding device 100 is designed reasonably in the limited space to achieve the best magnetic shielding effect; the magnetic shield apparatus 100 is composed of a magnetic shield tube 101 having an opening at one end, which is nested so that a better magnetic shield effect can be achieved than the magnetic shield apparatus 100 composed of a single-layer structure. The magnetic shielding cylinder 101 is formed by a plurality of magnetic shielding cylinders 101 with gradually decreasing geometric similar sizes, and the magnetic shielding cylinders are nested from inside to outside, as shown in fig. 3, which is a 1-1 cross-sectional view of the magnetic shielding device 100 in fig. 2, wherein the cross-section of the magnetic shielding device 100 is circular, and it can be understood that the axial projection shape of the magnetic shielding device 100 shown in fig. 3 is also circular. Preferably, the cross-sectional shape or the axial projection shape is a regular polygon having six or more sides, such as a circle, an ellipse, a square, or the like. Taking a circle as an example, as shown in fig. 3 and 9, in the radial direction, the shielding coefficient S1 is inversely related to the square of the diameter ratio between two adjacent layers, and the following is satisfied:
wherein i is a natural number, Δd i A distance between the i+1th magnetic shield cylinder 101 adjacent to the outside of the i-th magnetic shield cylinder 101, i=1 for the innermost magnetic shield cylinder 101; d (D) i The i-th magnetic shield cylinder 101 outer diameter is shown. Thus setting the spacing Deltad between the layers i= D i+1 -D i The size of the vehicle-mounted space is limited, and the shielding performance is ensured to be maximum as far as possible. It can be understood that when the cross-sectional shape or the axial projection of the magnetic shield cylinder 101 is an ellipse, a square, or a regular polygon with six or more sides, a plurality of magnetic shield cylinders 101 are concentrically arranged, and the magnetic shield cylinders are designed and stacked according to the above principle, and the distance Δd between two adjacent layers may satisfy the above constraint.
The relationship of the axial shielding coefficient S2 in the axial direction of the magnetic shield cylinder 101 and the cylinder depth ratio between the adjacent two layers satisfies:
wherein L is i Is the length of the ith magnetic shield cylinder 101 in the axial direction; in the axial direction, the constraint condition that one side of the cylinder is opened and the total length is fixed is considered, so that one side of the cylinder bottom is relatively dense in actual design, and the axial spacing of the cylinder openings of each cylinder at the cylinder opening side is equal, so that the axial shielding performance is optimal. As shown in fig. 9, in the axial direction of the magnetic shield cylinder 101, the pitch Δl between the cylinder openings of the adjacent magnetic shield cylinders 101 is equal, and the pitch Δl between the cylinder bottoms of the adjacent magnetic shield cylinders 101 is equal; and Deltal<Δl. The spacing deltal between the bottoms is also equal.
Further: as shown in fig. 6, the shock absorbing device 200 includes:
and (2) a base: the base is fixed at the bottom of the magnetic shielding device 100, a fixing part is arranged on the base, and the base is fixed at the bottom of the carriage through the fixing part, so that the magnetic shielding device 100 is fixed at the bottom of the carriage;
damping layer: the damping layer is an elastic cushion block; the shock absorbing layer is disposed between the base and the magnetic shield apparatus 100.
Further: the fixing part is a lock catch, and the lock catch is arranged on the base; corresponding anchor points are preset at the bottom of the carriage; the lock catch and the anchor point are locked so as to fix the base at the bottom of the carriage; the lock catch is provided with an elastic structure; and/or the fixing part is a bolt and a screw hole, the base and the bottom of the carriage are provided with screw holes, and the base is fixed at the bottom of the carriage by using the bolt;
the elastic cushion block is made of rubber containing nonmagnetic or weak magnetic reinforcing materials. The non-magnetic or weak magnetic reinforcing material is bakelite, epoxy resin, high molecular weight polyethylene, etc., and glass fiber, carbon fiber reinforced bakelite, epoxy resin, high molecular weight polyethylene material, not limited to the above materials.
The elastic structure is a structure which is partially made of elastic materials or is made of elastic structures such as springs, and the elastic structure can buffer external impact force during running.
Further, in order to strengthen the cushioning, a cushion pad 401 may be provided between the base and the magnetic shield device 100 and between the base and the vehicle cabin. The cushion 401 uses an elastic material having a cushioning effect.
The performance of the magnetic shielding cylinder is one of the key factors of the operation of the whole magnetoencephalography system, and compared with the magnetoencephalography system arranged at a fixed position in a hospital, the vehicle-mounted magnetoencephalography system has higher requirements on vibration, and slight changes of magnetic environment are likely to be perceived by an acquisition array and influence signal acquisition. In order to avoid the influence of vehicle vibration on the magnetic shielding cylinder, as shown in fig. 6, a fixed base is purposefully arranged below the magnetic shielding cylinder, the base is made of aluminum alloy, the base and the bottom of a carriage box body are fixed through bolts, a rubber cushion block containing non-magnetic reinforcing materials is used between the base and the bottom of the box body, and a damper capable of automatically adjusting damping coefficients is arranged on an axle to serve as primary damping; the base reserves lock catches at four corners, and locks the four lock catches with anchor points reserved on the bottom plate when the vehicle runs; the base is connected with the magnetic shielding cylinder 101 through an aluminum profile structure, a rubber cushion block with the thickness of 1.5cm is added between the base and the magnetic shielding cylinder 101 to serve as secondary shock absorption, shock caused by shaking of a vehicle body is reduced to the greatest extent in a two-stage shock absorption mode, and meanwhile the base can ensure that the magnetic shielding cylinder 101 cannot shift or collide with the inner wall of a carriage in the moving process of the vehicle; the vehicle-mounted brain magnetic map system is fixed with the bottom of a carriage through the base and the bolts, the base and the bottom of the carriage are provided with the shock absorbers capable of automatically adjusting damping coefficients, meanwhile, the buffer pads 401 are paved on all connecting surfaces, magnetic materials are avoided being used as much as possible on the basis of guaranteeing stability, the lock catch reserved on the base is locked with the anchor point on the vehicle when the vehicle runs, the lock catch adopts an elastic structure, a certain deformation degree is achieved, and the transportation safety is further enhanced.
Further: as shown in fig. 4, the power module 301 includes:
isolation filtering unit:
the isolation filtering unit is connected with an external power supply,
the isolation filtering unit includes: a capacitor with a cross-connected input end, a transformer with a core and a cross-connected output end;
the input/output cables of the isolation filter unit use double shielded wires;
the isolation filter unit is arranged in the electrostatic shielding shell;
and the voltage stabilizing unit is used for: the voltage stabilizing unit includes: the device comprises a voltage regulating module, a sampling circuit, a servo driving module and a control circuit;
the power supply output by the isolation filtering unit is input into the voltage stabilizing unit, and the voltage stabilizing unit controls the servo motor to rotate so as to drive the voltage regulating module to regulate the voltage by comparing the input voltage sample with the output voltage sample, so that a power supply with stable voltage is output;
a power supply unit:
the power supply unit includes a battery; the power supply unit receives the power supply of the stable voltage output by the voltage stabilizing unit and charges the battery with direct current; the power supply unit outputs alternating current to supply power for the vehicle-mounted magnetoencephalography system; the cable of power supply unit output alternating current is double shielded wire.
After the vehicle-mounted magnetoencephalography system is carried to a designated position, a power supply mode can be selected according to the actual situation of a site, such as power taking from municipal 220V, providing stable energy input by using an additional diesel generator or using uninterrupted power supply; in order to ensure stable operation of the device in the case of uninterruptible power supplies, a minimum of 5KVA is required. However, no matter what energy supply mode is adopted, electromagnetic interference is inevitably introduced from the outside, and the magnetoencephalography system is used as a weak magnetic acquisition signal system, is very sensitive to the electromagnetic interference, and the electromagnetic interference from the outside can influence the magnetoencephalography signal acquisition.
In order to effectively reduce the interference caused by the power supply of an external power supply, the direct coupling between an energy supply input end and a vehicle-mounted magnetoencephalography system is required to be avoided, and as shown in fig. 4, an isolation filter unit is arranged at the input end of the vehicle-mounted magnetoencephalography system. At the power input end, a Y capacitor is respectively connected between PE pairs by a power line L, N in a bridging way, so that higher harmonics of the input end are filtered, and common mode interference of power input is reduced; and the output end of the isolation and voltage stabilizing unit is connected with the primary side and the secondary side of PE, input and output in a crossing way with the Y capacitor, so that the conduction common mode interference is further reduced; the isolation filter unit transformer comprises an iron core, and the transmission of high-frequency hybrid waves to a signal line of a magnetoencephalography system is effectively restrained by utilizing the characteristic of high-frequency loss, so that the quality of the whole input voltage is improved.
Meanwhile, in order to further improve the anti-interference capability, an electrostatic shielding layer is added between the input and the output, and an electrostatic shielding shell is added to the whole isolation filter unit; on the other hand, double shielding wires are adopted before and after the isolation filtering unit so as to shield the radiation interference of the external environment in the complex environment. The EMC problem introduced by the power input is solved by the means, and the anti-interference capability of the magnetoencephalography system is isolated and improved.
In addition, the important problem to be solved is to prevent the instability of an external power supply, including unstable power supply and unstable voltage, which can affect the precision equipment of the magnetoencephalography collecting system. In order to avoid the problems of system failure, device damage, scanning interruption and the like caused by sudden power failure, a power supply unit is arranged, and when the sudden power failure occurs, a battery of the power supply unit is switched to supply power. When the external power supply supplies power normally, the rectifier firstly converts alternating current into direct current, one part of the direct current is used for charging the power supply, and the other part of the direct current is converted into alternating current through the inverter and is output to the vehicle-mounted magnetoencephalography system for power supply; when the main input fails or is disconnected, the battery is used as a power supply, and the output direct current is converted into alternating current power supply of the vehicle-mounted brain magnetic diagram system through the inverter.
In order to avoid the influence of unstable voltage, a voltage stabilizing unit is arranged, as shown in fig. 5, the sampling circuit samples the input voltage and the output voltage, and after the sampling of the input voltage and the output voltage is compared and calculated, the servo motor is driven to rotate to drive a potential slice of the voltage regulator to slide, the output voltage is stabilized at 220V by adjusting the input-output ratio, the voltage stabilizing precision is +/-1V, and the voltage after the voltage stabilizing is connected into the magnetoencephalography system through double shielding wires. The calculation mode is as follows: v (V) out =V in (1+L 1 /L 2 ) This process is achieved by adjusting L 1 /L 2 Ratio of step by step V out Adjusting to 220V + -1V. Thereby ensuring the voltage stability of the input power supply of the magnetoencephalography system.
Further: the noise management module 303 includes:
a data acquisition unit: data acquisition is carried out on the noise signals;
and a processing unit: and respectively calculating the noise value of each channel, calculating the correlation coefficient between the noise value and the noise threshold according to the preset noise threshold of each channel, normalizing the correlation coefficient into a normalized correlation coefficient, and using the normalized correlation coefficient to automatically compensate the channel gain. The channel gain automatic compensation may use a conventional noise reduction algorithm, which is not described in detail herein.
The processing unit provides an automatic gain compensation method suitable for the magnetoencephalography system, and improves signal stability to a certain extent.
Further: the data transmission module 305: comprising the following steps:
a data encryption unit:
encrypting the original data to be transmitted according to a preset encryption algorithm to obtain encrypted data;
identity information generation unit:
calculating an information hash value of the original data by using a preset hash function calculation method as data identity information of the original data, wherein the data identity information is used for verifying the integrity of the received data;
a data transfer unit:
and the network is connected with the terminal equipment, and the encrypted data and the data identity information are sent to the terminal equipment.
Further: the acquisition management apparatus 300 further includes a remote diagnosis module 306, the remote diagnosis module 306 being mounted on the terminal device;
the remote diagnostic module 306 includes:
a data verification unit:
the data verification unit decodes the encrypted data received by the terminal device according to a decryption algorithm corresponding to a preset encryption algorithm to obtain the original data, verifies whether the original data is complete according to the data identity information, and if the original data is incomplete, sends a retransmission request to the data transmission module 305;
remote diagnosis client:
and displaying the original data on the remote diagnosis client according to a preset template for remote diagnosis.
Through a preset encryption algorithm and a corresponding decryption algorithm, the data security in the data transmission process can be ensured, the privacy of a patient is prevented from being revealed, the integrity of the data can be ensured through verifying the identity information of the data, and the inaccuracy of the data caused by packet loss and the like is prevented. The remote diagnosis module 306 presents the collected data information in a preset template, so that the data information can be checked during remote diagnosis, other conventional functions required for remote diagnosis are not repeated here, and the data information can be set according to the needs.
The main control module can control the start and stop time of data acquisition and check the acquired data in real time; meanwhile, the data transmission module can be configured with a 5G wireless route, and the wireless route is connected through the cable main control module; the doctor selectively processes the acquired data according to the requirements through a remote diagnosis module, such as transmitting the acquired data to a hospital network center and the like;
the data transmission module can also be connected with the Internet through a network such as the Internet Ethernet and the like provided by a place where the cable connection system is located, and can also be connected with the Internet through a WIFI protocol and the like to send data to the terminal equipment.
The remote diagnosis module also has a remote diagnosis and report generation function.
The data acquisition module 304 may further be provided with a scanning bed for accommodating a patient, where the scanning bed is connected with the magnetic shielding cylinder 101 through a non-magnetic track, and the magnetic detection array is located at the head of the scanning bed, and when data is acquired, the magnetic detection array is sent into the magnetic shielding cylinder to perform acquisition by moving a horizontal track located on the bed body of the scanning bed. The scanning bed is a non-magnetic scanning bed.
An example of the vehicle-mounted magnetoencephalography system in actual use is given below, the system is loaded in a carriage, and a scanning room, an equipment room and an operation room are arranged in the carriage; the magnetic shielding cylinder is mainly used for shielding external magnetic field interference, namely providing a magnetic shielding environment for brain magnetic diagram signal acquisition so as to reduce magnetic interference to the level required by the system; the patient lies on the scanning bed, and enters the magnetic shielding cylinder together with the magnetic detection array during scanning; the operation room is an operation area, the main control module is arranged in the operation room, and the main control module and equipment in the scanning room communicate in a preset cable mode and synchronously receive and transmit signals; a power supply module is arranged between the devices to provide energy input for the magnetoencephalography system; other modules may be provided at the equipment or with the master control module at the operator's room and the remote diagnostic module at the remote terminal. The equipment room, the operation room and the scanning room can be set into independent rooms through the partition boards, and a passage channel is arranged, in this case, an observation window is reserved between the operation room and the scanning room, so that a doctor can observe a patient at any time; the virtual region dividing line can also be used for dividing the region and leaving a proper channel for the passage of doctors and patients.
Example 3
On the basis of example 2, further:
as shown in fig. 10, the magnetic shielding cylinder can be replaced by a part of carriage which is arranged between magnetic shielding, so that a corresponding scanning bed is not required to send a patient into the magnetic shielding cylinder any more, only a non-magnetic condition is required to be met and the magnetic shielding cylinder has a supporting function, data acquisition can be performed, the patient can lie on the scanning bed during scanning, and the non-magnetic scanning bed can be changed into a non-magnetic scanning chair as shown in fig. 10, so that the wearable detector array and the movable acquisition in a magnetic shielding effective area are realized.
A door passing through the shielding room and the operation room is arranged between the magnetic shielding room and the operation room, and the door is made of the same material as the shielding room except the supporting frame and also plays a role of shielding.
Correspondingly presetting an acquisition line into a shielding room through a waveguide tube; therefore, the position of the waveguide tube needs to be reserved between the magnetic shields; and reserving a camera position between magnetic shields, and displaying the video signal on a monitoring screen of an operation room in real time, so that a patient can be observed conveniently.
Example 4
Based on embodiment 2, the transmission modes of the data transmission module may be two modes: a real-time transmission mode and a backup transmission mode.
In a real-time transmission mode, the software provides an option of whether to automatically send or not after entering a patient acquisition interface, if the user selects to automatically send, the data is automatically sent to a remote server after the data acquisition is finished, the remote server can perform data analysis after receiving the data, and the function of completing functional diagnosis and providing a diagnosis report by combining the structural image of the patient can be provided; if automatic transmission is not selected when the data acquisition interface is entered, manual transmission or non-transmission can be selected again according to the prompt after the data acquisition is completed. The real-time transmission mode flow is shown in fig. 7.
The data can also be selected to be sent to a remote server for remote diagnosis and backup or to a backup server for data backup by using a backup mode after a certain acquisition task is completed. After the user selects the data to be backed up according to the actual needs, selecting a backup function provided by the vehicle-mounted magnetoencephalography system to start backup, informing that the backup is successful after the backup is completed, and simultaneously marking the backed up data; if the backup fails in the process, the system will perform the re-backup operation according to the set number of attempts until the data backup is successful, or the maximum number of attempts is reached and the backup failure is notified, and at the same time, inquires whether to re-backup, the flow is shown in fig. 8.
Through the two modes, the data transmission mode can be flexibly selected, and the user can use the data transmission mode conveniently. Meanwhile, the data backup function prevents loss caused by data loss and the like, and improves the safety of the data.
In the embodiment of the invention, the vehicle-mounted magnetoencephalography system can be loaded in a vehicle, and it is understood that the vehicle comprises vehicles such as trains and automobiles, is not limited to the application, and can be applied to vehicles such as aircrafts.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, or alternatives falling within the spirit and principles of the invention.

Claims (9)

1. The utility model provides a on-vehicle brain magnetic map system which characterized in that: comprising the following steps:
magnetic shield device (100): shielding the magnetic interference signal to make the magnetic interference signal value smaller than or equal to a preset magnetic interference signal threshold value;
the acquisition management device (300) comprises a power supply module (301) and a data acquisition module (304); the power module (301) provides an uninterrupted power supply for the vehicle-mounted brain magnetic diagram system and filters electromagnetic interference signals of the power supply; the data acquisition module (304) comprises a magnetic detection array for acquiring brain magnetic signals, and the data acquisition module (304) is arranged in the magnetic shielding device (100);
wherein the magnetic shielding device (100) is formed by nesting a plurality of magnetic shielding barrels (101) with openings at one ends, and the inner diameter value of the innermost magnetic shielding barrel (101) at the position with the largest inner diameter is W; in the radial direction of the magnetic shielding cylinders (101), the distance Deltad between adjacent magnetic shielding cylinders (101) i The method meets the following conditions: from the inner magnetic shielding cylinder (101) to the outer magnetic shielding cylinder (101) in the direction delta d i Gradually increasing; the shielding coefficient S1 in the radial direction is inversely related to the square of the diameter ratio between the adjacent two layers, satisfying:
i represents an ith magnetic shield cylinder (101), i is a natural number, D i Represents the i-th magnetic shielding cylinder outer diameter, D i+1 Represents the i+1th magnetic shield cylinder outer diameter adjacent to the i-th magnetic shield cylinder outer side;
in the axial direction of the magnetic shielding barrels (101), the intervals delta L between barrel openings of adjacent magnetic shielding barrels (101) are equal, the intervals delta L between barrel bottoms of adjacent magnetic shielding barrels (101) are equal, and delta L < delta L; the relationship of the shielding factor S2 in the axial direction with the barrel depth ratio between the adjacent two layers satisfies:
L i for the axial length of the ith magnetic shielding cylinder, L i+1 Represents the length in the axial direction of the (i+1) th magnetic shield cylinder adjacent to the outside of the (i) th magnetic shield cylinder.
2. The system of claim 1, wherein: further comprises:
damping device (200): the magnetic shielding device (100) is fixed in a carriage of the vehicle-mounted magnetoencephalography system to be installed through the damping device (200);
the acquisition management device (300) further comprises:
noise management module (303): monitoring and compensating the noise value, controlling the noise value within a preset noise threshold,
a data transmission module (305): the method comprises the steps of sending acquired brain magnetic signal data to terminal equipment to be connected; main control module (302): the main control module (302) is connected with and controls the data acquisition module (304), the noise management module (303) and the data transmission module (305), and acquires and displays the data acquired by the data acquisition module (304) and the noise management module (303).
3. The system of claim 1, wherein:
the magnetic shielding barrels (101) are made of materials with magnetic permeability being larger than or equal to a preset magnetic permeability threshold value, and the number of the magnetic shielding barrels (101) is larger than or equal to 2.
4. The system according to claim 2, wherein:
the shock absorbing device (200) includes:
and (2) a base: the base is fixed at the bottom of the magnetic shielding device (100), and a fixing part is arranged on the base, and the base is fixed at the bottom of the carriage through the fixing part, so that the magnetic shielding device (100) is fixed at the bottom of the carriage;
damping layer: the damping layer is an elastic cushion block; the shock absorbing layer is disposed between the base and the magnetic shield device (100).
5. The system as recited in claim 4, wherein:
the fixing part is a lock catch, and the lock catch is arranged on the base; corresponding anchor points are preset at the bottom of the carriage; the lock catch and the anchor point are locked so as to fix the base at the bottom of the carriage; the lock catch is provided with an elastic structure; and/or the fixing part is a bolt and a screw hole, the base and the bottom of the carriage are provided with screw holes, and the base is fixed at the bottom of the carriage by using the bolt;
the elastic cushion block is made of rubber containing nonmagnetic or weak magnetic reinforcing materials.
6. The system of claim 1, wherein:
the power supply module (301) comprises:
isolation filtering unit:
the isolation filtering unit is connected with an external power supply,
the isolation filtering unit includes: a capacitor with a cross-connected input end, a transformer with a core and a cross-connected output end;
the input/output cables of the isolation filter unit use double shielded wires;
the isolation filter unit is arranged in the electrostatic shielding shell;
and the voltage stabilizing unit is used for:
comprising the following steps: the device comprises a voltage regulating module, a sampling circuit, a servo driving module and a control circuit;
the power supply output by the isolation filtering unit is input into the voltage stabilizing unit, and the voltage stabilizing unit controls the servo motor to rotate so as to drive the voltage regulating module to regulate the voltage by comparing the input voltage sample with the output voltage sample, so that a power supply with stable voltage is output;
a power supply unit:
the power supply unit includes a battery; the power supply unit receives the power supply of the stable voltage output by the voltage stabilizing unit and charges the battery with direct current; the power supply unit outputs alternating current to supply power for the vehicle-mounted magnetoencephalography system; the cable of power supply unit output alternating current is double shielded wire.
7. The system according to claim 2, wherein:
the noise management module (303) comprises:
a data acquisition unit: data acquisition is carried out on the noise signals;
and a processing unit: and respectively calculating the noise value of each channel, calculating the correlation coefficient between the noise value and the noise threshold according to the preset noise threshold of each channel, normalizing the correlation coefficient into a normalized correlation coefficient, and using the normalized correlation coefficient to automatically compensate the channel gain.
8. The system according to claim 2, wherein:
the data transmission module (305): comprising the following steps:
a data encryption unit:
encrypting the original data to be transmitted according to a preset encryption algorithm to obtain encrypted data;
identity information generation unit:
calculating an information hash value of the original data by using a preset hash function calculation method as data identity information of the original data, wherein the data identity information is used for verifying the integrity of the received data;
a data transfer unit:
and the network is connected with the terminal equipment, and the encrypted data and the data identity information are sent to the terminal equipment.
9. The system as recited in claim 8, wherein:
the acquisition management device (300) further comprises a remote diagnosis module (306), wherein the remote diagnosis module (306) is installed on the terminal equipment;
the remote diagnostic module (306) includes:
a data verification unit:
the data verification unit decodes the encrypted data received by the terminal equipment according to a decryption algorithm corresponding to a preset encryption algorithm to obtain the original data, verifies whether the original data is complete according to the data identity information, and sends a retransmission request to the data transmission module (305) if the original data is incomplete;
remote diagnosis client:
and displaying the original data on the remote diagnosis client according to a preset template for remote diagnosis.
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