CN1166369C - Nanometer level pilose antler and pilose antler product and their prepn process - Google Patents
Nanometer level pilose antler and pilose antler product and their prepn process Download PDFInfo
- Publication number
- CN1166369C CN1166369C CNB011334312A CN01133431A CN1166369C CN 1166369 C CN1166369 C CN 1166369C CN B011334312 A CNB011334312 A CN B011334312A CN 01133431 A CN01133431 A CN 01133431A CN 1166369 C CN1166369 C CN 1166369C
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- cornu cervi
- cervi pantotrichum
- oil
- suspension
- vegetable oil
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- Medicines Containing Plant Substances (AREA)
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Abstract
The present invention provides a nanometer level pilose antler or antler product which is a colloid liquid or suspension formed by a pilose antler or antler with the particle diameter of 10 to 1000 nm in liquid, wherein the weight ratio for which the pilose antler or antler accounts is from 0.5 to 80%. All ingredients of the products of the present invention are refined in various forms to nanometer level to realize that maximum utilization quantity is realized when the ingredients are utilized by human bodies. Thereby, the drug effect and the utilization rate of pilose antlers and antlers are increased.
Description
(1) technical field
What the present invention relates to is a kind of nanoscale new raw material, specifically a kind of Cornu Cervi Pantotrichum or Cornu Cervi goods that can be used for producing medicine or food, cosmetics and health product etc.The present invention also relates to the manufacture method of this Cornu Cervi Pantotrichum or Cornu Cervi goods.
(2) background technology
When utilizing Cornu Cervi Pantotrichum or Cornu Cervi to make medicine, food, cosmetics and health product adopt extraction methods or be ground into the direct applied method of coarse powder.But cause the waste of some compositions when extracting Cornu Cervi Pantotrichum or Cornu Cervi effective ingredient and nutritional labeling easily.All because the granule in the system is excessive, can not makes Cornu Cervi Pantotrichum, Cornu Cervi effective ingredient or nutritional labeling fully dissociate out, and then influence the absorption of effective ingredient or nutritional labeling and the transportation in blood when using with coarse powder.And record finds that Cornu Cervi Pantotrichum, Cornu Cervi are used as medicine after mostly being pulverizing from numerous at all times medical books, the report that especially rare heating decocts.
(3) summary of the invention
The object of the present invention is to provide a kind of nutritional labeling to keep high nanoscale Cornu Cervi Pantotrichum or the Cornu Cervi goods of effective rate of utilization complete, nutritional labeling.Purpose of the present invention also is to provide the manufacture method of this Cornu Cervi Pantotrichum or Cornu Cervi goods.Product of the present invention is gel-like fluid or the suspension that is formed in the Cornu Cervi Pantotrichum of 10～1000nm or any liquid of Cornu Cervi in water, vegetable oil, animal oil or vegetable oil and 1: 1 mixture of animal oil by particle diameter, and wherein the shared weight ratio of Cornu Cervi Pantotrichum or Cornu Cervi is at 0.5-80%.Product of the present invention is to be made by such method: Cornu Cervi Pantotrichum or Cornu Cervi are ground into 60-80 purpose coarse powder earlier, add 4-8 times water, vegetable oil, animal oil or vegetable oil and any liquid in 1: 1 the mixture of animal oil, make suspension, again suspension is placed NZJ type wet method nano grinder to be crushed to particle diameter at 10～1000nm.Product of the present invention has comprised the colloidal solution that is formed by the Cornu Cervi Pantotrichum of 10～100nm or Cornu Cervi in water solublity or liquid system such as fat-soluble, comprise the oil-in-water type or the water-in-oil type microemulsion of the whole 10～100nm of being granular systems that 10～100nm granular system or the effective ingredient among them and liquid form.Two kinds of forms can be arranged, a kind ofly in liquid, pulverize the granule that directly obtains system for solid in 10～100nm scope; The granule that the another kind of granule that forms in water-based system for butyrous effective ingredient forms in the oiliness system at the effective ingredient of the water oil-packaging type micro-emulsion of 10～100nm scope or aqueous is at the water-in-oil type microemulsion of 10～100nm scope; Wherein also comprise the true solution system that the dissolubility composition forms.Product of the present invention has comprised that also grain diameter is Cornu Cervi Pantotrichum or the Cornu Cervi suspension of 100～1000nm.This characteristic feature of an invention is: pulverize by the nanoscale in liquid, make the dissolubility composition in Cornu Cervi Pantotrichum and the Cornu Cervi directly be dissolved in the liquid; The indissolubility liquid component can form nanoscale Water-In-Oil or water oil-packaging type micro-emulsion with liquid; The indissolubility solid constituent can form sol system or suspension with liquid.All the components is refine to the utilization that reaches maximum when nanoscale can make composition be utilized by human body with various forms, so improve the drug effect and the utilization rate of Cornu Cervi Pantotrichum or Cornu Cervi.Product of the present invention can be used for the medicine that pharmaceutical raw material is produced various dosage forms, also can be used for various health foods, can also be used among the various cosmetics, is used in simultaneously in other products such as health product and also can produces good effect.This product can by number of ways contact with human body the generation effect as: (1), compositions such as medicine, health product, cosmetics, bath accessory by the skin surface transdermal administration enter blood of human body circulation process and enter blood for the Transdermal absorption through the skin of body surface.(2), compositions such as the medicine by the human body mucosal drug delivery, health product enter blood of human body circulation process and enter blood for the mucosa through human body absorbs.Comprise: oral mucosa form of administration, pulmonary's mucosal drug delivery dosage form, vaginal mucosa form of administration, rectal mucosa form of administration etc.(3), compositions such as oral drug, health food, health promoting beverage enter blood of human body circulation process and enter blood for absorbing through the digestive system after oral.(4), the medicine medicine by the injection system administration enters blood of human body circulation process for making medicine directly enter blood through the method for injecting.
(4) description of drawings
Fig. 1 is the electron micrograph of Cornu Cervi Pantotrichum under the 80.0KV X50K 100nm shooting condition;
Fig. 2 is the electron micrograph of Cornu Cervi Pantotrichum under the 80.0KV X100K 50nm shooting condition;
Fig. 3 is the electron micrograph of Cornu Cervi Pantotrichum under the 80.0KV X50K 50nm shooting condition.
(5) specific embodiment
For example the present invention is done more detailed description below:
Embodiment 1.Get Cornu Cervi Pantotrichum or Cornu Cervi 100Kg, be crushed to 80 orders, the water that adds 8 times is mixed with suspension, places NZJ type wet process disintegrator to be crushed to particle diameter at liquid again and reaches 10-100nm, forms colloidal solution.
Embodiment 2.Get Cornu Cervi Pantotrichum or Cornu Cervi 100Kg, be crushed to 80 orders, the vegetable oil that adds 8 times is mixed with suspension, places NZJ type wet process disintegrator to be crushed to particle diameter at liquid again and reaches 10-100nm, forms colloidal solution.
Embodiment 3.Get Cornu Cervi Pantotrichum or Cornu Cervi 100Kg, be crushed to 80 orders, the animal oil that adds 8 times is mixed with suspension, places NZJ type wet process disintegrator to be crushed to particle diameter at liquid again and reaches 10-100nm, forms colloidal solution.
Embodiment 4.Get Cornu Cervi Pantotrichum or Cornu Cervi 100Kg, be crushed to 80 orders, add 8 times vegetable oil and 1: 1 mixture of animal oil, be mixed with suspension, place NZJ type wet process disintegrator to be crushed to particle diameter again and reach 10-100nm, form colloidal solution at liquid.
Embodiment 5.Get Cornu Cervi Pantotrichum or Cornu Cervi 100Kg, be crushed to 80 orders, the water that adds 8 times is mixed with suspension, places NZJ type wet process disintegrator to be crushed to particle diameter at liquid again and reaches 100-1000nm, forms suspension.
Embodiment 6.Get Cornu Cervi Pantotrichum or Cornu Cervi 100Kg, be crushed to 80 orders, the vegetable oil that adds 8 times is mixed with suspension, places NZJ type wet process disintegrator to be crushed to particle diameter at liquid again and reaches 100-1000nm, forms suspension.
Embodiment 7.Get Cornu Cervi Pantotrichum or Cornu Cervi 100Kg, be crushed to 80 orders, the animal oil that adds 8 times is mixed with suspension, places NZJ type wet process disintegrator to be crushed to particle diameter at liquid again and reaches 100-1000nm, forms suspension.
Embodiment 8.Get Cornu Cervi Pantotrichum or Cornu Cervi 100Kg, be crushed to 80 orders, add 8 times vegetable oil and 1: 1 mixture of animal oil, be mixed with suspension, place NZJ type wet process disintegrator to be crushed to particle diameter again and reach 100-1000nm, form suspension at liquid.
Claims (6)
1, a kind of nanoscale Cornu Cervi Pantotrichum or Cornu Cervi goods, it is characterized in that: it is colloidal solution or the suspension that is formed in the Cornu Cervi Pantotrichum of 10～1000nm or any liquid of Cornu Cervi in water, vegetable oil, animal oil or vegetable oil and 1: 1 mixture of animal oil by particle diameter, and wherein the shared weight ratio of Cornu Cervi Pantotrichum or Cornu Cervi is at 0.5-80%.
2, nanoscale Cornu Cervi Pantotrichum according to claim 1 or Cornu Cervi goods, it is characterized in that: it is the colloidal solution that is formed in the Cornu Cervi Pantotrichum of 10～100nm or any liquid of Cornu Cervi in water, vegetable oil, animal oil or vegetable oil and 1: 1 mixture of animal oil by particle diameter, and wherein the shared weight ratio of Cornu Cervi Pantotrichum or Cornu Cervi is at 0.5-80%.
3, nanoscale Cornu Cervi Pantotrichum according to claim 1 or Cornu Cervi goods, it is characterized in that: it is the suspension that is formed in the Cornu Cervi Pantotrichum of 100～1000nm or any liquid of Cornu Cervi in water, vegetable oil, animal oil or vegetable oil and 1: 1 mixture of animal oil by particle diameter, and wherein the shared weight ratio of Cornu Cervi Pantotrichum or Cornu Cervi is at 0.5-80%.
4, the manufacture method of a kind of nanoscale Cornu Cervi Pantotrichum or Cornu Cervi goods, it is characterized in that: Cornu Cervi Pantotrichum or Cornu Cervi are ground into 60-80 purpose coarse powder earlier, add 4-8 times water, vegetable oil, animal oil or vegetable oil and any liquid in 1: 1 the mixture of animal oil, make suspension, again suspension is placed NZJ type wet method nano grinder to be crushed to particle diameter at 10～1000nm.
5, the manufacture method of nanoscale Cornu Cervi Pantotrichum according to claim 4 or Cornu Cervi goods, it is characterized in that: Cornu Cervi Pantotrichum or Cornu Cervi are ground into 60-80 purpose coarse powder earlier, add 4-8 times water, vegetable oil, animal oil or vegetable oil and any liquid in 1: 1 the mixture of animal oil, make suspension, again suspension is placed NZJ type wet method nano grinder to be crushed to particle diameter, make colloidal solution at 10～100nm.
6, the manufacture method of nanoscale Cornu Cervi Pantotrichum according to claim 4 or Cornu Cervi goods, it is characterized in that: Cornu Cervi Pantotrichum or Cornu Cervi are ground into 60-80 purpose coarse powder earlier, add 4-8 times water, vegetable oil, animal oil or vegetable oil and any liquid in 1: 1 the mixture of animal oil, make suspension, again suspension is placed NZJ type wet method nano grinder to be crushed to particle diameter, make suspension at 100～1000nm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011334312A CN1166369C (en) | 2001-11-07 | 2001-11-07 | Nanometer level pilose antler and pilose antler product and their prepn process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011334312A CN1166369C (en) | 2001-11-07 | 2001-11-07 | Nanometer level pilose antler and pilose antler product and their prepn process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1416820A CN1416820A (en) | 2003-05-14 |
| CN1166369C true CN1166369C (en) | 2004-09-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011334312A Expired - Fee Related CN1166369C (en) | 2001-11-07 | 2001-11-07 | Nanometer level pilose antler and pilose antler product and their prepn process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1166369C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007124618A1 (en) * | 2006-04-28 | 2007-11-08 | Lizhong Wang | Insulin-like growth factor-enriched nano-products of hairy antler and process for preparation thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106036837A (en) * | 2016-06-03 | 2016-10-26 | 通化师范学院 | Formula and preparation method of microcapsules prepared from deer horns and pilose antlers of sika deers |
-
2001
- 2001-11-07 CN CNB011334312A patent/CN1166369C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007124618A1 (en) * | 2006-04-28 | 2007-11-08 | Lizhong Wang | Insulin-like growth factor-enriched nano-products of hairy antler and process for preparation thereof |
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| Publication number | Publication date |
|---|---|
| CN1416820A (en) | 2003-05-14 |
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