CN116602665A

CN116602665A - Subcutaneous implantation device

Info

Publication number: CN116602665A
Application number: CN202210122932.8A
Authority: CN
Inventors: 杨志勇; 陆世龙
Original assignee: Mirror Life Suzhou Technology Co ltd
Current assignee: Mirror Life Suzhou Technology Co ltd
Priority date: 2022-02-09
Filing date: 2022-02-09
Publication date: 2023-08-18

Abstract

The invention relates to a subcutaneous implantation device, which comprises an application, an implantation seat, a sliding block, a sensing seat, a needle seat, an implantation needle, a sensor, a base, a driving device and a release device, wherein one end of the implantation seat is provided with an implantation hole; the sliding block is slidably arranged in the implantation seat and is positioned at one side of the implantation hole; the sensing seat is movably arranged at one end of the sliding block; the needle seat is arranged on the sliding block; the implantation needle is fixed on the needle seat and is movably inserted on the sensing seat; the sensor is arranged in the implantation needle, and a connecting plate of the sensor is arranged on the sensor seat; the base is movably inserted into the implantation hole, a fixing device which is arranged opposite to the sensing seat is arranged on the base, and the application is fixed at the bottom of the base; the driving device is arranged on the implantation seat, is connected with the sliding block and is used for driving the sliding block to drive the sensor and the implantation needle to be implanted into a human body and ejecting the base out of the implantation hole; the release device is arranged on the implantation seat and connected with the driving device for releasing the driving device. The device simple structure, use experience are good.

Description

Subcutaneous implantation device

Technical Field

The present invention relates to a device for subcutaneously implanting a sensor, in particular a subcutaneous implantation device.

Background

Subcutaneous implantable sensors are a type of sensor used for subcutaneous analyte measurement or transdermal monitoring, typically based on electrochemical sensors or optical sensors, which are used to obtain analyte presence or concentration data by measuring and analyzing target analytes in subcutaneous tissue fluid. The sensor needs to be implanted into a subcutaneous target position, can be continuously monitored in real time, and periodically uploads data to an upper computer or a cloud server through an external transmitter.

A typical subcutaneous implanted sensor, such as a continuous blood glucose monitoring sensor, is a sensor implanted in subcutaneous tissue to continuously measure glucose concentration and changes in biological tissue fluids. When glucose in tissue fluid diffuses to the periphery of the sensor, the conversion functional sensitive unit of the sensor can convert the blood glucose concentration into an electric signal for digital acquisition, and the data can be displayed as the blood glucose concentration after being processed by a certain algorithm.

The current continuous blood glucose sensor abandons the form of a hard steel needle, and adopts a film type flexible micro needle sensor based on a flexible substrate, so that the advantages of the flexible sensor are obvious, better use experience can be provided for a user, particularly after implantation, the flexible micro needle can be bent to a certain extent along with the limb activity of the user, the physical damage to an implantation position can be greatly reduced, and the foreign body sensation of the user is greatly relieved. However, due to the flexibility of such flexible microneedle sensors, the strength of the flexible microneedle sensors cannot maintain the strength of the flexible microneedle sensors penetrating through the skin during the implantation process, so that the flexible microneedle sensors cannot be directly implanted into subcutaneous sites, and the implanter and the implantation method which are suitable for the rigid microneedle sensors are not suitable any more. How to implant a flexible sensor subcutaneously is a problem to be solved.

Disclosure of Invention

In order to solve the problems, the invention provides a subcutaneous implantation device with high implantation and needle withdrawal speed, stable angle and simple structure, which comprises the following specific technical scheme:

a subcutaneous implant device comprising an application, further comprising: an implantation seat, wherein one end of the implantation seat is provided with an implantation hole; the sliding block is slidably arranged in the implantation seat and is positioned at one side of the implantation hole; the sensing seat is movably arranged at one end of the sliding block; the needle seat is arranged on the sliding block and is positioned at the top of the sensing seat; the implantation needle is fixed on the needle seat and is movably inserted on the sensing seat; the sensor is arranged in the implantation needle, and a connecting plate of the sensor is arranged on the sensor seat; the base is movably inserted into the implantation hole, a fixing device which is arranged opposite to the sensing seat is arranged on the base, and the application is fixed at the bottom of the base; the driving device is arranged on the implantation seat, is connected with the sliding block and is used for driving the sliding block to drive the sensor and the implantation needle to be implanted into a human body, and the base is ejected out of the implantation hole; and the release device is arranged on the implantation seat, connected with the driving device and used for releasing the driving device.

Preferably, the implantation seat is provided with a sliding groove, and the sliding groove is positioned at one end of the implantation hole and is communicated with the implantation hole; the sliding block is inserted in the sliding groove in a sliding way, a guide seat is arranged on the sliding block, and the guide seat is inserted in the sliding groove in a sliding way.

Preferably, the driving device includes: the driving seat is provided with an eccentric shaft, the eccentric shaft is movably inserted into the driving groove, the driving groove is arranged on the sliding block, and the driving groove is perpendicular to the moving direction of the sliding block; one end of the coil spring is connected with the driving seat; the winding seat is rotatably arranged on the driving seat and connected with the other end of the coil spring, a pawl is arranged on the winding seat, and the pawl is arranged opposite to a ratchet arranged on the implantation seat; and a handle mounted on the winding seat and located outside the implantation seat.

Further, the method further comprises the following steps: the gland, the gland is fixed on the axis of rotation at coiling seat top, the axis of rotation is rotated and is installed in the rotation hole of implantation seat, coiling seat with the gland is located respectively the both sides of rotation hole.

The top of the winding seat is provided with a slot, the handle is provided with an inserting block matched with the slot, the inserting block is movably inserted into the slot, and the inserting block and the slot are used for driving the winding seat to rotate by the handle.

Preferably, the release device comprises: the release seat is rotatably arranged on the implantation seat and is positioned on one side of the driving seat, a plurality of locking grooves are formed in an annular array at the bottom of the release seat, a release shaft is arranged at the top of the release seat, a plurality of release blocks and positioning blocks are arranged in an annular array on the release shaft, the positioning blocks are positioned between the release blocks and the release seat, and the positioning blocks and the release blocks are arranged in a staggered manner; the release switch is inserted on the implantation seat and the release shaft in a sliding manner, a plurality of release limiting blocks and anti-rotation blocks are arranged on the release switch, the release limiting blocks are movably inserted between the adjacent release blocks or the adjacent positioning blocks, and the anti-rotation blocks are movably inserted in anti-rotation grooves of the implantation seat; the locking block is arranged on one side of the driving seat and is movably inserted into the locking groove; when the release limiting block is positioned on one side of the release block or the positioning block, the locking block is inserted into the locking groove, when the release limiting block moves from the release block to the positioning block, the release seat rotates, and the locking block leaves the locking groove and is reinserted into the locking groove after rotating for one circle.

The release switch is provided with an anti-falling block, and the anti-falling block is positioned in the implant seat.

Preferably, one end of the sliding block is provided with at least two first movable buckles symmetrically, and the sensing seat is movably arranged on the first movable buckles; the base is provided with a fixing groove and a fixing buckle, and the fixing groove and the fixing buckle are used for fixing the sensing seat.

Further, at least two second movable buckles are symmetrically arranged on the sliding block, and the needle seat is arranged on the second movable buckles.

Compared with the prior art, the invention has the following beneficial effects:

the subcutaneous implantation device provided by the invention has the advantages of simple structure, few parts, low cost, high implantation and needle withdrawal speed, stable implantation angle, simple operation and good use experience, and the sensor is not easy to be brought out of the needle after the needle is withdrawn.

Drawings

FIG. 1 is an elevation view of a subcutaneous implant device;

FIG. 2 is a side view of a subcutaneous implant device;

FIG. 3 is a cross-sectional view of a subcutaneous implant device;

FIG. 4 is an exploded view of a subcutaneous implant device;

FIG. 5 is a schematic view of a partial structure of the release device and the drive device;

FIG. 6 is a schematic diagram of the structure of the drive socket;

FIG. 7 is a schematic view of the structure of the winding seat;

FIG. 8 is a schematic view of the structure of the release seat;

FIG. 9 is a schematic diagram of the structure of the release switch;

FIG. 10 is a schematic view of the structure of the slider with the sensor mount and the hub;

fig. 11 is a schematic view of an explosive structure of the needle mount, the implant needle, the sensor, and the sensor mount;

FIG. 12 is a schematic structural view of a base;

fig. 13 is a schematic view of the structure of the base, sensor mount and applicator when implanted in a human body.

Detailed Description

The invention will now be further described with reference to the accompanying drawings.

As shown in fig. 1 to 13, a subcutaneous implant device includes an application 87, an implant seat, a slider 2, a sensor seat 84, a needle seat 83, an implant needle 82, a sensor 86, a base 81, a driving means, and a releasing means.

The implantation seat is a shell and comprises an upper cover 11 and a lower cover 12, and the upper cover 11 and the lower cover 12 are connected through screws. The top of the upper cover 11 is provided with a release hole 17 and a rotation hole 19, the release hole 17 is provided with a plurality of anti-rotation grooves 18, and the anti-rotation grooves 18 are arranged along the axis of the release hole 17. The bottom of the rotation hole 19 is provided with ratchets 10, and the ratchets 10 are arranged in an annular array. The lower cover 12 is provided with a sliding groove 13 and a positioning shaft 16, one end of the lower cover 12 is provided with a connecting seat 14, the connecting seat 14 is provided with an implantation hole 15, the implantation hole 15 is positioned at one end of the sliding groove 13, the implantation hole 15 is communicated with the sliding groove 13, and the base 81 is movably inserted into the implantation hole 15. The positioning shaft 16 is located at the other end of the sliding groove 13.

An application 87 is secured to the bottom of the base 81.

The slide block 2 is provided with a guide seat 21, the guide seat 21 is slidably inserted into the sliding groove 13 to guide the slide block 2, and the position of the slide block 2 is limited, so that the slide block 2 can only reciprocate along the axis of the sliding groove 13. The guide seat 21 is provided with a driving groove 22, the driving groove 22 is a kidney-shaped groove, and the length direction of the driving groove 22 is perpendicular to the moving direction of the sliding block 2.

One end of the sliding block 2 is provided with a first movable buckle 23 and a second movable buckle 24 which are symmetrically provided with two, the second movable buckle 24 is positioned above one side of the first movable buckle 23, the sensing seat 84 is movably arranged on the first movable buckle 23, and the needle seat 83 is movably arranged on the second movable buckle 24. The second movable catch 24 facilitates replacement of the hub 83, enabling reuse of the subcutaneous implant.

The implantation needle 82 is a C-shaped needle, an opening is provided in the implantation needle 82, and the implantation needle 82 is fixed to the needle holder 83. The sensor 86 is provided with a connection board 861, the connection board 861 is provided with a contact, and the contact is used for being connected with a detector, and the detector detects relevant data (such as blood sugar concentration detection) in a human body. The sensor 86 is movably inserted inside the implant needle 82 and is connected to the connection plate 861 through an opening in the implant needle 82. The sensor seat 84 is provided with a mounting groove 841, and the connecting plate 861 is mounted in the mounting groove 841 through the gasket 85.

The base 81 is provided with a fixing groove 811 and a fixing buckle 812, the fixing groove 811 is matched with the sensor seat 84, when the sensor seat 84 is inserted into the fixing groove 811, the fixing buckle 812 is clamped on the sensor seat 84, and the fixing groove 811 and the fixing buckle 812 realize fixing of the sensor seat 84.

The driving means comprises a driving seat 3, a coil spring 41, a winding seat 5, a handle 43 and a gland 42. One side of the driving seat 3 is provided with a locking block 31, the driving seat 3 is provided with a spring groove 32, a coil spring 41 is movably inserted into the spring groove 32, and one end of the coil spring 41 is fixed on a fixing clamping groove 35 on one side of the driving seat 3. The bottom of the driving seat 3 is provided with an eccentric shaft 33, and the eccentric shaft 33 is movably inserted in the driving groove 22. The winding seat 5 is provided with a winding shaft 51, and the winding shaft 51 is rotatably mounted on the driving seat 3 and fixedly connected with the other end of the coil spring 41. The outer circle surface of the winding seat 5 is provided with a pawl 52, the pawl 52 is elastically arranged, the top of the winding seat 5 is provided with a rotating shaft 53, the rotating shaft 53 is rotatably arranged in the rotating hole 19, the gland 42 is fixed on the top of the rotating shaft 53 through screws, the winding seat 5 and the gland 42 are respectively positioned on two sides of the rotating hole 19, and the gland 42 and the winding shaft 51 limit the axial movement of the rotating shaft 53. Pawl 52 engages ratchet 10. The top of the winding shaft 51 is provided with a slot 54, the handle 43 is provided with an inserting block 431 matched with the slot 54, the inserting block 431 is movably inserted into the slot 54, the handle 43 is implanted outside the seat, and the inserting block 431 and the slot 54 are used for driving the handle 43 to rotate the winding seat 5. Slot 54 is a cross slot and insert 431 is a cross block.

The release means comprise a release seat 7, a release switch 6 and a locking block 31. The bottom of the release seat 7 is provided with a positioning hole 72 and a plurality of locking grooves 71, the locking grooves 71 are annularly arranged around the positioning hole 72, and the locking block 31 is movably inserted in the locking grooves 71. The positioning hole 72 is rotatably arranged on the positioning shaft 16, the top of the release seat 7 is provided with a release shaft 73, the release shaft 73 is provided with a plurality of release blocks 74 and positioning blocks 75 in an annular array, the positioning blocks 75 are positioned between the release blocks 74 and the release seat 7, and the positioning blocks 75 and the release blocks 74 are arranged in a staggered mode. The release switch 6 is slidably inserted in the release hole 17 and the release shaft 73, the release switch 6 is provided with a plurality of release limiting blocks 61 and anti-rotation blocks 62, the release limiting blocks 61 are movably inserted between adjacent release blocks 74 or positioning blocks 75, the anti-rotation blocks 62 are movably inserted in the anti-rotation grooves 18, and the anti-rotation blocks 62 are in one-to-one correspondence with the anti-rotation grooves 18. The two sides of the upper bottom of the release switch 6 are symmetrically provided with anti-falling blocks 63, and the anti-falling blocks 63 are positioned at the bottom of the release hole 17 to prevent the release switch 6 from pulling out the release hole 17.

When the release stopper 61 is located on the release block 74 or the positioning block 75 side, the lock block 31 is inserted into the lock groove 71, and when the release stopper 61 is moved from the release block 74 to the positioning block 75, the release seat 7 is rotated, and the lock block 31 is separated from the lock groove 71 and is reinserted into the lock groove 71 after one rotation.

In the initial state, the release switch 6 is in the inserted state, the release stopper 61 is inserted at one side of the positioning block 75, and the locking block 31 is inserted in the locking groove 71. The release prevention block 63 restricts the extraction position of the release switch 6. When the release switch 6 is pulled out, the release limiting block 61 slides from the positioning block 75 to the release block 74, at the moment, the release seat 7 rotates by a small angle, the rotating angle is the included angle between the positioning block 75 and the release block 74, at the moment, the release seat 7 rotates to the release position, the locking block 31 is still limited in the locking groove 71, and the release limiting block 61 is positioned at one side of the release block 74. When the release switch 6 is pressed down, the release limiting block 61 slides from the release block 74 to the positioning block 75, the release seat 7 continues to rotate by an angle which is still the included angle between the release block 74 and the positioning block 75, at this time, the locking block 31 slides out of the locking groove 71, after the driving seat 3 rotates once, the locking block 31 is reinserted into the locking groove 71, and the locking block 31 is limited in the locking groove 71.

The release switch 6 is safe in the pressed state and can prevent misoperation.

In use, the release switch 6 is first depressed, then the insert 431 on the handle 43 is inserted into the slot 54 of the winding shaft 51, then the handle 43 is rotated clockwise to tighten the coil spring 41, and after the coil spring 41 is tightened in place, the handle 43 is pulled out. Since the locking block 31 on the driving seat 3 is inserted in the locking groove 71, and the release stopper 61 on the release switch 6 is movably inserted at one side of the positioning block 75, the driving seat 3 cannot rotate. Then the release switch 6 is pulled upwards, the release limiting block 61 moves from the positioning block 75 to the release block 74, the release seat 7 rotates to the release position, the connecting seat 14 is pressed to the implantation position of the human body, the application 87 is attached to the human body, then the release switch 6 is pressed down, the driving seat 3 rotates for one circle under the action of the coil spring 41, and the sliding block 2 completes the implantation and needle withdrawal actions under the action of the eccentric shaft 33 and the driving groove 22. When the driving seat 3 drives the sliding block 2 to move downwards through the eccentric shaft 33 and the driving groove 22, the sliding block 2 drives the sensing seat 84 and the needle seat 83 to move rapidly towards the base 81, the implantation needle 82 drives the sensor 86 to puncture the application 87 and the skin to be implanted into the human body, the sensing seat 84 is inserted into the fixing groove 811, and the fixing buckle 812 fixes the sensing seat 84. Then the slide block 2 returns under the action of the eccentric shaft 33 and the driving groove 22, the sensing seat 84 is separated from the first movable buckle 23, the needle seat 83 drives the implantation needle 82 to return, and the sensor 86 stays in the human body when the implantation needle 82 returns due to the opening on the implantation needle 82.

The release action of the coil spring 41 is very quick, so that the time for implantation and needle withdrawal is very short and the implantation experience is good. And because the needle is rapidly withdrawn, and the sensor 86 is positioned in the implantation needle 82, the sensor 86 is not easily carried out during needle withdrawal, and the success rate of implantation is high. The implantation needle 82 adopts a semi-open design, so that the implantation needle 82 can avoid the connecting part at the rear end of the sensor 86 when being withdrawn after implantation, and the needle withdrawal is smoothly completed without being carried out together with the sensor 86.

The novel implant device has the advantages of simple and compact integral structure, few parts, low cost, convenience in operation, repeated use, capability of setting different coil springs according to different crowds, different implantation speeds and good use experience.

The subcutaneous implanted device utilizes the resilience force of the coil spring to realize the processes of automatic implantation and automatic needle withdrawal, has exquisite structure, simple realization principle, reduces the manufacturing difficulty and saves the cost. Meanwhile, the device can be reset, can be implanted repeatedly, and reduces the use cost. The elastic force of the coil spring can be regulated, the implantation process can be implemented aiming at different skins, implantation can be successfully ensured, rapid needle withdrawal can be ensured, pain of a subject is reduced, and non-inductive implantation is realized.

The technical principle of the present invention is described above in connection with the specific embodiments. The description is made for the purpose of illustrating the general principles of the invention and should not be taken in any way as limiting the scope of the invention. Other embodiments of the invention will occur to those skilled in the art from consideration of the specification and practice of the invention without the need for inventive faculty, and are within the scope of the claims.

Claims

1. A subcutaneous implant device comprising an application (87), characterized in that it further comprises:

an implantation seat, one end of which is provided with an implantation hole (15);

a slider (2), the slider (2) being slidably mounted in the implantation seat and being located at one side of the implantation hole (15);

the sensing seat (84) is movably arranged at one end of the sliding block (2);

a needle seat (83), wherein the needle seat (83) is arranged on the sliding block (2) and is positioned at the top of the sensing seat (84);

an implantation needle (82), wherein the implantation needle (82) is fixed on the needle seat (83) and is movably inserted on the sensing seat (84);

a sensor (86), the sensor (86) being mounted within the implantation needle (82), a connection plate (861) of the sensor (86) being mounted on the sensing seat (84);

the base (81) is movably inserted into the implantation hole (15), a fixing device which is opposite to the sensing seat (84) is arranged on the base (81), and the application (87) is fixed at the bottom of the base (81);

the driving device is arranged on the implantation seat, is connected with the sliding block (2) and is used for driving the sliding block (2) to drive the sensor (86) and the implantation needle (82) to be inserted into a human body and withdraw from the implantation needle (82), so that the sensor (86) is implanted into the human body; and

And the release device is arranged on the implantation seat, connected with the driving device and used for releasing the driving device.

2. Subcutaneous implant device according to claim 1, characterized in that the implant seat is provided with a sliding groove (13), which sliding groove (13) is located at one end of the implant hole (15) and communicates with the implant hole (15); the sliding block (2) is inserted into the sliding groove (13) in a sliding mode, a guide seat (21) is arranged on the sliding block (2), and the guide seat (21) is inserted into the sliding groove (13) in a sliding mode.

3. A subcutaneous implant according to claim 1, characterized in that the drive means comprise:

the driving seat (3), the driving seat (3) is provided with an eccentric shaft (33), the eccentric shaft (33) is movably inserted into the driving groove (22), the driving groove (22) is arranged on the sliding block (2), and the driving groove (22) is perpendicular to the moving direction of the sliding block (2);

a coil spring (41), wherein one end of the coil spring (41) is connected with the driving seat (3);

the winding seat (5) is rotatably arranged on the driving seat (3) and is connected with the other end of the coil spring (41), a pawl (52) is arranged on the winding seat (5), and the pawl (52) is arranged opposite to a ratchet (10) arranged on the implantation seat; and

A handle (43), said handle (43) being mounted on said winding seat (5) and being located outside said implantation seat.

4. A subcutaneous implant device according to claim 3, further comprising: the gland (42), gland (42) is fixed on rotation axis (53) at coiling seat (5) top, rotation axis (53) rotation is installed in implantation seat's rotation hole (19), coiling seat (5) with gland (42) are located respectively the both sides of rotation hole (19).

5. A subcutaneous implant device according to claim 3, characterized in that the top of the winding seat (5) is provided with a slot (54), the handle (43) is provided with an insert (431) matched with the slot (54), the insert (431) is movably inserted into the slot (54), and the insert (431) and the slot (54) are used for the handle (43) to drive the winding seat (5) to rotate.

6. A subcutaneous implant according to claim 3, characterized in that the release means comprises:

the release seat (7), the release seat (7) is rotationally arranged on the implantation seat and is positioned on one side of the driving seat (3), a plurality of locking grooves (71) are formed in an annular array at the bottom of the release seat (7), a release shaft (73) is arranged at the top of the release seat (7), a plurality of release blocks (74) and positioning blocks (75) are arranged in an annular array on the release shaft (73), the positioning blocks (75) are positioned between the release blocks (74) and the release seat (7), and the positioning blocks (75) and the release blocks (74) are arranged in a staggered mode;

the release switch (6) is slidably inserted into the implantation seat and the release shaft (73), a plurality of release limiting blocks (61) and anti-rotation blocks (62) are arranged on the release switch (6), the release limiting blocks (61) are movably inserted between adjacent release blocks (74) or positioning blocks (75), and the anti-rotation blocks (62) are movably inserted into anti-rotation grooves (18) of the implantation seat; and

The locking block (31) is arranged on one side of the driving seat (3) and is movably inserted into the locking groove (71);

when the release limiting block (61) is positioned on one side of the release block (74) or the positioning block (75), the locking block (31) is inserted into the locking groove (71), when the release limiting block (61) moves from the release block (74) to the positioning block (75), the release seat (7) rotates, and the locking block (31) leaves the locking groove (71) and is reinserted into the locking groove (71) after rotating for one circle.

7. Subcutaneous implant device according to claim 6, characterized in that the release switch (6) is provided with an anti-drop block (63), said anti-drop block (63) being located inside the implant seat.

8. A subcutaneous implant device according to any of claims 1 to 7, characterized in that one end of the slider (2) is provided with a first movable clasp (23) symmetrically provided with at least two, the sensor seat (84) being movably mounted on the first movable clasp (23);

the base (81) is provided with a fixing groove (811) and a fixing buckle (812), and the fixing groove (811) and the fixing buckle (812) are used for fixing the sensing seat (84).

9. Subcutaneous implant device according to claim 8, characterized in that said slider (2) is symmetrically provided with at least two second movable catches (24), said needle hub (83) being mounted on said second movable catches (24).