CN116602303A - Pesticide composition and preparation and application thereof - Google Patents
Pesticide composition and preparation and application thereof Download PDFInfo
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- CN116602303A CN116602303A CN202310578853.2A CN202310578853A CN116602303A CN 116602303 A CN116602303 A CN 116602303A CN 202310578853 A CN202310578853 A CN 202310578853A CN 116602303 A CN116602303 A CN 116602303A
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- China
- Prior art keywords
- chlorfenapyr
- composition
- pesticide composition
- pesticide
- trifluoromethyl nicotinamide
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 73
- 239000000575 pesticide Substances 0.000 title claims abstract description 55
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- CWFOCCVIPCEQCK-UHFFFAOYSA-N chlorfenapyr Chemical compound BrC1=C(C(F)(F)F)N(COCC)C(C=2C=CC(Cl)=CC=2)=C1C#N CWFOCCVIPCEQCK-UHFFFAOYSA-N 0.000 claims abstract description 51
- JUIWZYBJXUPIKF-UHFFFAOYSA-N 4-(trifluoromethyl)pyridine-3-carboxamide Chemical compound NC(=O)C1=CN=CC=C1C(F)(F)F JUIWZYBJXUPIKF-UHFFFAOYSA-N 0.000 claims abstract description 32
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 14
- 239000004480 active ingredient Substances 0.000 claims abstract description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 27
- 239000002917 insecticide Substances 0.000 claims description 16
- 239000000375 suspending agent Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 claims description 9
- 238000009472 formulation Methods 0.000 claims description 9
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 claims description 9
- 229920001296 polysiloxane Polymers 0.000 claims description 9
- 239000000230 xanthan gum Substances 0.000 claims description 9
- 229920001285 xanthan gum Polymers 0.000 claims description 9
- 229940082509 xanthan gum Drugs 0.000 claims description 9
- 235000010493 xanthan gum Nutrition 0.000 claims description 9
- -1 polydimethylsiloxane Polymers 0.000 claims description 8
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 6
- 230000000361 pesticidal effect Effects 0.000 claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 4
- 239000012752 auxiliary agent Substances 0.000 claims description 4
- 239000002270 dispersing agent Substances 0.000 claims description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N formaldehyde Natural products O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
- 239000002562 thickening agent Substances 0.000 claims description 4
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical group COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 claims description 2
- 108010010803 Gelatin Proteins 0.000 claims description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 2
- QPUYECUOLPXSFR-UHFFFAOYSA-N alpha-methyl-naphthalene Natural products C1=CC=C2C(C)=CC=CC2=C1 QPUYECUOLPXSFR-UHFFFAOYSA-N 0.000 claims description 2
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 claims description 2
- 239000002518 antifoaming agent Substances 0.000 claims description 2
- 125000003118 aryl group Chemical group 0.000 claims description 2
- 239000004202 carbamide Substances 0.000 claims description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 2
- 239000013530 defoamer Substances 0.000 claims description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 2
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 claims description 2
- 239000004495 emulsifiable concentrate Substances 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 claims description 2
- 229920000159 gelatin Polymers 0.000 claims description 2
- 235000019322 gelatine Nutrition 0.000 claims description 2
- 235000011852 gelatine desserts Nutrition 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 2
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 2
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 2
- 235000019832 sodium triphosphate Nutrition 0.000 claims description 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 2
- 239000004562 water dispersible granule Substances 0.000 claims description 2
- 230000000749 insecticidal effect Effects 0.000 claims 6
- 239000011734 sodium Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 19
- 231100000674 Phytotoxicity Toxicity 0.000 abstract description 11
- 230000002195 synergetic effect Effects 0.000 abstract description 10
- 230000002045 lasting effect Effects 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 26
- 241000238631 Hexapoda Species 0.000 description 17
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 14
- 238000000034 method Methods 0.000 description 13
- 230000000052 comparative effect Effects 0.000 description 12
- 231100000419 toxicity Toxicity 0.000 description 12
- 230000001988 toxicity Effects 0.000 description 12
- 241000196324 Embryophyta Species 0.000 description 11
- 229940079593 drug Drugs 0.000 description 8
- 239000003814 drug Substances 0.000 description 8
- MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 6
- LYUDWCGKBDSWET-UHFFFAOYSA-L aluminum;magnesium;sulfate Chemical compound [Mg+2].[Al+3].[O-]S([O-])(=O)=O LYUDWCGKBDSWET-UHFFFAOYSA-L 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 238000004383 yellowing Methods 0.000 description 6
- 241000219112 Cucumis Species 0.000 description 5
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 5
- 241000500437 Plutella xylostella Species 0.000 description 5
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 5
- 230000001965 increasing effect Effects 0.000 description 5
- 238000011835 investigation Methods 0.000 description 5
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- 230000006378 damage Effects 0.000 description 4
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- 230000009467 reduction Effects 0.000 description 4
- 244000003416 Asparagus officinalis Species 0.000 description 3
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- 239000007858 starting material Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 230000004083 survival effect Effects 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
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- 240000007124 Brassica oleracea Species 0.000 description 2
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 2
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 2
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 2
- 240000008067 Cucumis sativus Species 0.000 description 2
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 2
- 241001237160 Kallima inachus Species 0.000 description 2
- 241000255777 Lepidoptera Species 0.000 description 2
- 241000256247 Spodoptera exigua Species 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
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- 230000005764 inhibitory process Effects 0.000 description 2
- 230000036244 malformation Effects 0.000 description 2
- 239000000447 pesticide residue Substances 0.000 description 2
- 230000008635 plant growth Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 241001600407 Aphis <genus> Species 0.000 description 1
- 241000255789 Bombyx mori Species 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 239000005900 Flonicamid Substances 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 241000209504 Poaceae Species 0.000 description 1
- 244000088415 Raphanus sativus Species 0.000 description 1
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- WWBXZKQQXUFSED-UHFFFAOYSA-N [Na].O=C.C1=CC=C2C(S(=O)(=O)OC)=CC=CC2=C1 Chemical compound [Na].O=C.C1=CC=C2C(S(=O)(=O)OC)=CC=CC2=C1 WWBXZKQQXUFSED-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000000856 effect on pests Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000005562 fading Methods 0.000 description 1
- RLQJEEJISHYWON-UHFFFAOYSA-N flonicamid Chemical compound FC(F)(F)C1=CC=NC=C1C(=O)NCC#N RLQJEEJISHYWON-UHFFFAOYSA-N 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000003090 pesticide formulation Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
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- 238000007665 sagging Methods 0.000 description 1
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- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P7/00—Arthropodicides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P7/00—Arthropodicides
- A01P7/04—Insecticides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Insects & Arthropods (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to the technical field of pesticides, and particularly discloses a pesticide composition, a preparation and application thereof. The active ingredients of the pesticide composition comprise 4-trifluoromethyl nicotinamide and chlorfenapyr. The pesticide composition provided by the invention has obvious synergistic effect between two components, and the 4-trifluoromethyl nicotinamide and the chlorfenapyr are compounded according to a certain proportion, so that the use amount of the chlorfenapyr can be reduced, the pesticide composition has obvious quick-acting property, the lasting period is prolonged, the control effect of the chlorfenapyr on target pests is improved, the application times are reduced, the generation of the target pests on the chlorfenapyr resistance is slowed down, and the phytotoxicity risk of the chlorfenapyr is effectively reduced.
Description
Technical Field
The invention relates to the technical field of pesticides, in particular to a pesticide composition, a preparation and application thereof.
Background
Pesticides are indispensable special agricultural production data in modern agriculture. Due to complex ecological conditions, the number of harmful organisms such as diseases, insects, grasses, mice and the like of crops is thousands, and hundreds of harmful organisms can be seriously damaged throughout the year. The frequent occurrence or large-scale occurrence of plant diseases and insect pests can cause great loss of agriculture and forestry, and the application of pesticides is a quick, efficient, simple and necessary control means at present.
In the using process of the pesticide, as the application frequency is increased and the using amount is increased, the sensitivity of the target to the pesticide is gradually reduced and the resistance is gradually increased; in the actual use process, in order to pursue the prevention effect, the use amount of the pesticide is increased, which is a very common phenomenon, and a series of problems such as pesticide residue, food safety and the like are further generated. The chlorfenapyr is a broad-spectrum and efficient pesticide, has good stomach toxicity activity and certain contact activity on pests, and has good interlayer conductivity, and the using amount of the chlorfenapyr tends to increase year by year due to the special action mechanism.
However, in the using process of chlorfenapyr, with the increase of the application amount, the chlorfenapyr inevitably generates phytotoxicity to certain organisms, so that the chlorfenapyr is greatly limited in the actual application and popularization processes. Therefore, the development of the pesticide composition which can reduce the using amount of chlorfenapyr and the pesticide application frequency and has good control effect has very important significance.
Disclosure of Invention
In order to reduce the using amount of chlorfenapyr and the pesticide application frequency, the invention provides a pesticide composition.
The invention also provides a preparation containing the pesticide composition.
The invention also provides an application of the pesticide composition.
In order to achieve the above purpose, the embodiment of the invention adopts the following technical scheme:
the invention provides an insecticide composition, which is characterized in that: the effective components of the composition comprise 4-trifluoromethyl nicotinamide and chlorfenapyr.
Compared with the prior art, the pesticide composition provided by the invention takes 4-trifluoromethyl nicotinamide and chlorfenapyr as main active ingredients, and has obvious synergistic effect between the two components; the chlorfenapyr has the effects of contact killing and stomach poisoning on pests, and the 4-trifluoromethyl nicotinamide has no obvious biological activity on the pests, so that the speed of increasing the resistance of the pests to the chlorfenapyr in the using process can be well relieved, and the problem of frequent drug damage in the using process of the chlorfenapyr is solved. The 4-trifluoromethyl nicotinamide and the chlorfenapyr are compounded in a certain proportion, so that the using amount of the chlorfenapyr can be obviously reduced under the condition of not affecting the pesticide effect, the obvious synergistic effect is achieved, and the pest control effect is improved. The pesticide composition provided by the invention provides a solution to the problems of using safety, pesticide residue and the like of chlorfenapyr, plays a role in reducing and enhancing efficiency, and has a remarkable significance in delaying the generation of resistance of lepidoptera pests to chlorfenapyr, reducing the using amount of chlorfenapyr and reducing the generation of phytotoxicity.
Preferably, the mass ratio of the 4-trifluoromethyl nicotinamide to the chlorfenapyr is 1:20-20:1.
Further, the mass ratio of the 4-trifluoromethyl nicotinamide to the chlorfenapyr is 1:10-10:1.
Further, the mass ratio of the 4-trifluoromethyl nicotinamide to the chlorfenapyr is 3:2-1:4.
Preferably, the pesticide composition comprises the following components in percentage by weight: 10-30% of active ingredient, 10-14% of auxiliary agent and the balance of solvent.
Preferably, the auxiliary agent comprises at least one of a dispersant, a defoamer, an antifreezing agent or a thickener.
Preferably, the dispersing agent is at least one of phenethyl phenol polyoxyethylene polyoxypropylene ether, methyl naphthalene sulfonate formaldehyde condensate, aromatic sulfonate, sodium lignin sulfonate or sodium tripolyphosphate; further preferable is a sodium methyl naphthalene sulfonate formaldehyde condensate of phenethyl phenol polyoxyethylene polyoxypropylene ether.
Preferably, the antifoaming agent is at least one of polydimethylsiloxane or silicone; silicone is further preferred.
Preferably, the antifreezing agent is at least one of glycerol, ethylene glycol, propylene glycol or urea; glycerol is further preferred.
Preferably, the thickener is at least one of xanthan gum, magnesium aluminum silicate, gelatin, sodium carboxymethyl cellulose or sodium polyacrylate; xanthan gum is further preferred.
Preferably, the solvent is at least one of water or ethanol.
The invention also provides an insecticide preparation containing the 4-trifluoromethyl nicotinamide and chlorfenapyr.
Preferably, the pesticide preparation is emulsifiable concentrate, water dispersible granules, granules or suspending agents; it is further preferred that the pesticide formulation is a suspending agent.
The invention also provides application of the pesticide composition containing 4-trifluoromethyl nicotinamide and chlorfenapyr in pest control.
The pesticide composition containing 4-trifluoromethyl nicotinamide and chlorfenapyr provided by the invention can obviously reduce the usage amount of chlorfenapyr under the condition of not affecting the pesticide effect by reasonably compounding the active components, has obvious synergistic effect among the components, and improves the control effect on pests. Can delay the generation of resistance of pests to chlorfenapyr, reduce the use amount of chlorfenapyr, and has obvious significance for reducing the generation of phytotoxicity.
Detailed Description
The present invention will be described in further detail with reference to the following examples in order to make the objects, technical solutions and advantages of the present invention more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
In order to better illustrate the embodiments of the present invention, the following is further illustrated by examples.
Example 1
The embodiment provides an insecticide suspending agent, which comprises the following components in parts by weight:
0.48 kg of 4-trifluoromethyl nicotinamide, 9.52 kg of chlorfenapyr, 1.6 kg of phenethyl phenol polyoxyethylene polyoxypropylene ether, 0.16 kg of naphthalene formaldehyde methylnaphthalene sulfonate condensate, 0.6 kg of silicone, 6.67 kg of glycerol, 80 kg of water, 0.3 kg of xanthan gum and 0.67 kg of magnesium aluminum sulfate.
The preparation method of the pesticide suspending agent comprises the following steps:
weighing 4-trifluoromethyl nicotinamide, chlorfenapyr, phenethyl phenol polyoxyethylene polyoxypropylene ether, naphthalene formaldehyde methylnaphthalene sulfonate condensate, silicone, glycerol and water according to the design proportion, mixing and stirring uniformly, adding into a dispersing machine, adding equal amount of zirconia beads, grinding for 4 hours at 2000r/min, adding xanthan gum and magnesium aluminum sulfate for modulation, and sieving to obtain the pesticide suspending agent.
Example 2
The embodiment provides an insecticide suspending agent, which comprises the following components in parts by weight:
10 kg of 4-trifluoromethyl nicotinamide, 10 kg of chlorfenapyr, 3 kg of phenethyl phenol polyoxyethylene polyoxypropylene ether, 2.5 kg of naphthalene formaldehyde methylnaphthalene sulfonate condensate, 0.4 kg of silicone, 4 kg of glycerol, 69.1 kg of water, 0.3 kg of xanthan gum and 0.7 kg of magnesium aluminum sulfate.
The preparation method of the pesticide suspending agent comprises the following steps:
weighing 4-trifluoromethyl nicotinamide, chlorfenapyr, phenethyl phenol polyoxyethylene polyoxypropylene ether, naphthalene formaldehyde methylnaphthalene sulfonate condensate, silicone, glycerol and water according to the design proportion, mixing and stirring uniformly, adding into a dispersing machine, adding equal amount of zirconia beads, grinding for 4 hours at 2000r/min, adding xanthan gum and magnesium aluminum sulfate for modulation, and sieving to obtain the pesticide suspending agent.
Example 3
The embodiment provides an insecticide suspending agent, which comprises the following components in parts by weight:
28.57 kg of 4-trifluoromethyl nicotinamide, 1.43 kg of chlorfenapyr, 5 kg of phenethyl phenol polyoxyethylene polyoxypropylene ether, 4.2 kg of naphthalene formaldehyde methylnaphthalene sulfonate condensate, 0.3 kg of silicone, 4 kg of glycerol, 56 kg of water, 0.2 kg of xanthan gum and 0.3 kg of magnesium aluminum sulfate.
The preparation method of the pesticide suspending agent comprises the following steps:
weighing 4-trifluoromethyl nicotinamide, chlorfenapyr, phenethyl phenol polyoxyethylene polyoxypropylene ether, naphthalene formaldehyde methylnaphthalene sulfonate condensate, silicone, glycerol and water according to the design proportion, mixing and stirring uniformly, adding into a dispersing machine, adding equal amount of zirconia beads, grinding for 4 hours at 2000r/min, adding xanthan gum and magnesium aluminum sulfate for modulation, and sieving to obtain the pesticide suspending agent.
Comparative example 1
The comparative example provides an insecticide suspending agent, and the specific preparation method is as follows:
this comparative example was prepared using the same starting materials and preparation method as example 2, except that 4-trifluoromethyl nicotinamide was replaced with chlorfenapyr in an equal weight to prepare an insecticide suspension.
Comparative example 2
The comparative example provides an insecticide suspending agent, and the specific preparation method is as follows:
this comparative example was prepared using the same starting materials and preparation method as example 2, except that chlorfenapyr was replaced with an equivalent weight of 4-trifluoromethyl nicotinamide to make the pesticide suspension.
Comparative example 3
The comparative example provides an insecticide suspending agent, and the specific preparation method is as follows:
this comparative example was prepared using the same starting materials and preparation method as example 2, except that 4-trifluoromethyl nicotinamide was replaced with equal weight flonicamid to prepare the pesticide suspension.
For measuring the synergistic effect of 4-trifluoromethyl nicotinamide and chlorfenapyr, a grand cloud method is selected, the toxicity index (T1) and co-toxicity coefficient (CTC) of the pesticide composition are calculated according to the following formula, and the effect is evaluated:
toxicity index (T1) = (standard insecticide LC 50 Single dose LC 50 )×100；
Theoretical drug toxicity index (TT 1) =drug a toxicity index x drug content (%) in the drug mixture+drug B toxicity index x drug content (%) in the drug mixture;
actual measured toxicity index of the mixture (AT 1) = (standard insecticide LC) 50 Mixing LC 50 )×100；
Blend co-toxicity coefficient (CTC) = (blend measured toxicity index/blend theoretical toxicity index) ×100.
In the formula, LC 50 -a toxicity measurement of the substance.
Wherein, standard insecticide: the invention relates to a compound with a toxicity index of 100, which takes 4-trifluoromethyl nicotinamide as a standard pesticide;
single dose: 4-trifluoromethyl nicotinamide and chlorfenapyr;
and (3) mixing: the 4-trifluoromethyl nicotinamide and chlorfenapyr are compounded according to different proportions.
And the effect of the blend co-toxicity coefficient (CTC) was evaluated according to the following criteria:
the co-toxicity coefficient of the mixture, CTC is less than 80, and the mixture is antagonistic;
the coefficient of toxicity of the mixed agent is equal to or more than 80 and equal to or less than 120, and the mixed agent has superposition effect;
the co-toxicity coefficient of the mixture, CTC is more than 120, and the synergistic effect is achieved.
The biological activity of melon borers in the room was then determined as follows:
the indoor biological test is measured by a blade dipping method. And selecting 2-year-old larvae with uniform development and uniform size to hunger for 4 hours. Fresh insect-free cucumber leaves are taken, leaf discs with the diameter of 2cm are manufactured, washed and dried, soaked in liquid medicines with different proportions and concentrations for 10s, taken out and dried, placed in a cell culture plate paved with agar for moisture preservation, inoculated with 1 insect test per hole, and repeated for 30 insects test per proportion. The same procedure was followed with clear water without insecticide added as a control. The death of the larvae was checked 72 hours after treatment, and the co-toxicity coefficient of the mixture was calculated.
The experimental results are shown in table 1 below:
TABLE 1 determination of indoor toxicity of pesticide compositions of different proportions to Aphis cerana
The test result shows that the composition ratio of the chlorfenapyr and the 4-trifluoromethyl nicotinamide has a synergistic effect within the range of 20:1-1:20, and the synergistic effect of the chlorfenapyr and the 4-trifluoromethyl nicotinamide is optimal when the ratio of the two active components is 1:1.
Test example 1
Test object: melon silk borer field control
The pesticide composition formulations of examples 1-3 and comparative examples 1-3 of the present invention were used in field control trials on melon borers and a blank control was set as a clear water treatment.
The test was carried out in Shandong's life-saving vegetable greenhouse, cucumber with serious damage, uniform degree and uniform growth was selected as the test crop, and applied per mu in the amounts listed in table 2 below, and the plants were spray-treated with the pesticide composition 1 time. Each test was set with 4 duplicate cells, arranged in random groups, each cell having an area of about 15m 2 The method for investigating fixed-point fixed-strain is adopted, 5 points are investigated in each district, 5 strains are investigated in each district, the number of insect population base is investigated before administration, the survival number of insect population is investigated 1d, 3d, 7d and 14d after administration, and the occurrence of crop phytotoxicity is investigated 3 days after administration.
The phytotoxicity is classified as follows:
grade 0, asymptomatic;
grade 1, slightly wilting the heart leaves or not significantly changing, slightly wilting the whole plant (leaves turn dark green, leaves droop);
stage 2, leaf wilting (sagging), leaf margin yellowing, whole plant wilting, leaf yellowing and curling from the leaf tip, part of leaf withering spots, and plant growth inhibition;
stage 3, yellow and curled heart leaves, partial malformation and atrophy, whole plant fading and yellowing, increase of dead leaf area (40% -70%), plant growth inhibition and atrophy tendency;
grade 4, malformation and curling of heart leaves, serious yellowing and occurrence of dead spots, serious overall yellowing of plants, dead leaf area reaching more than 70%, plant atrophy and growth arrest;
grade 5, the plant is seriously withered, the withered area reaches more than 95%, and only a small amount of heart leaves with serious yellowing are remained, or the whole plant is dead.
The field control effect test and the drug effect calculation method are as follows:
rate of reduction of insect population = (number of insects before administration-number of insects after administration)/number of insects before administration x 100%
Control effect= (treated rate of reduction of insect population-control rate of reduction of insect population)/(1-control rate of reduction of insect population) ×100%.
The test results are shown in Table 2:
table 2 field control effect of pesticide composition formulations on melon silk moth
As can be seen from the data in Table 2, the control effect of the two mixtures on the melon borers is better than that of each single mixture, and the mixtures show obvious synergism in each investigation period.
Test example 2
Test object: plutella xylostella field control
The pesticide composition formulations of examples 1 to 3 and comparative examples 1 to 3 of the present invention were used for field control experiments on plutella xylostella, and a blank control was set as a clear water treatment.
The test was carried out on the cabbage field of Shijia in Hebei province, and cabbages having serious damage, uniform degree and uniform growth were selected as test crops, which were applied per mu in the amounts listed in table 3 below, and the plants were spray-treated 1 time with the pesticide composition. 4 repeated cells are set in each test, 5 points are investigated in each cell by adopting a fixed-point fixed-strain investigation method, 10 strains are investigated in each point, the number of insect population is investigated before the application, the survival number of insect population is investigated 1d, 3d, 7d and 14d after the application, the occurrence condition of crop phytotoxicity is investigated 3d after the application, and the phytotoxicity grading standard is shown in test example 1.
The field control effect of the pesticide composition on plutella xylostella was calculated according to the above-described method for calculating the efficacy of the pesticide in test example 1.
The test results are shown in Table 3:
table 3 field control of plutella xylostella with pesticide composition formulations
As can be seen from the data in table 3, the control effect of both the mixtures on plutella xylostella is better than that of each single mixture, and the mixtures show obvious synergistic effect in each investigation period.
Test example 3
Test object: beet armyworm field control
The pesticide composition formulations of examples 1-3 and comparative examples 1-3 of the present invention were used in field control experiments on asparagus caterpillar, and a blank control was set as a clear water treatment.
The test was carried out on vegetable planting bases in suburban areas of the Luoyang province in Henan, and radishes with serious harm, consistent degree and uniform growth vigor were selected as test crops and applied in the amounts listed in the following Table 3 per mu, and the plants were spray-treated 1 time with the pesticide composition. 4 repeated cells are set in each test, 5 points are investigated in each cell by adopting a fixed-point fixed-strain investigation method, 20 strains are investigated in each point, the number of insect population is investigated before the application, the survival number of insect population is investigated 1d, 3d, 7d and 14d after the application, the occurrence condition of crop phytotoxicity is investigated 3d after the application, and the phytotoxicity grading standard is shown in test example 1.
The field control effect of the pesticide composition on asparagus caterpillar was calculated according to the above-described method for calculating the efficacy of the pesticide composition in experimental example 1.
The test results are shown in Table 4:
table 4 field control of spodoptera exigua by pesticide composition formulations
As can be seen from the data in table 4, the control effect of both the mixtures on asparagus caterpillar is better than that of each single mixture, and the mixtures show obvious synergistic effect in each investigation period.
The pesticide composition containing 4-trifluoromethyl nicotinamide and chlorfenapyr provided by the invention can obviously improve the control effect on lepidoptera pests through reasonable compounding of active components, obviously reduce the use amount and the application frequency of pesticides, delay the time of the pests on the pesticide and reduce the risk of phytotoxicity of chlorfenapyr.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, or alternatives falling within the spirit and principles of the invention.
Claims (10)
1. An insecticide composition characterized in that: the effective components of the composition comprise 4-trifluoromethyl nicotinamide and chlorfenapyr.
2. The insecticidal composition of claim 1, wherein: the mass ratio of the 4-trifluoromethyl nicotinamide to the chlorfenapyr is 1:20-20:1.
3. The insecticidal composition of claim 1, wherein: the mass ratio of the 4-trifluoromethyl nicotinamide to the chlorfenapyr is 1:10-10:1.
4. The insecticidal composition of claim 1, wherein: the mass ratio of the 4-trifluoromethyl nicotinamide to the chlorfenapyr is 3:2-1:4.
5. The insecticidal composition of any one of claims 1-4, wherein: comprises the following components in percentage by mass: 10-30% of active ingredient, 10-14% of auxiliary agent and the balance of solvent.
6. The insecticidal composition of claim 5, wherein: the auxiliary agent comprises at least one of dispersing agent, defoamer, antifreezing agent or thickener.
7. The insecticidal composition of claim 6, wherein: the dispersing agent is at least one of phenethyl phenol polyoxyethylene polyoxypropylene ether, methyl naphthalene sulfonate sodium formaldehyde condensate, aromatic sulfonate, sodium lignin sulfonate or sodium tripolyphosphate;
the defoaming agent is at least one of polydimethylsiloxane or silicone;
the antifreezing agent is at least one of glycerol, ethylene glycol, propylene glycol or urea;
the thickener is at least one of xanthan gum, magnesium aluminum silicate, gelatin, sodium carboxymethyl cellulose or sodium polyacrylate;
the solvent is at least one of water or ethanol.
8. An insecticide formulation, characterized in that: comprising the pesticidal composition of any one of claims 1-7.
9. The insecticide formulation of claim 8, wherein: the pesticide preparation is emulsifiable concentrate, water dispersible granules, granules or suspending agents.
10. Use of the pesticidal composition of any one of claims 1 to 7 or the pesticidal formulation of any one of claims 8 to 9 for controlling pests.
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