CN116594456A - Frequency adjusting device and method and electric field therapeutic apparatus - Google Patents

Frequency adjusting device and method and electric field therapeutic apparatus Download PDF

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Publication number
CN116594456A
CN116594456A CN202310497600.2A CN202310497600A CN116594456A CN 116594456 A CN116594456 A CN 116594456A CN 202310497600 A CN202310497600 A CN 202310497600A CN 116594456 A CN116594456 A CN 116594456A
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frequency
signal
current value
module
optimal treatment
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刘俊
熊凌志
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Hunan Antai Kangcheng Biotechnology Co ltd
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Hunan Antai Kangcheng Biotechnology Co ltd
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    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05FSYSTEMS FOR REGULATING ELECTRIC OR MAGNETIC VARIABLES
    • G05F1/00Automatic systems in which deviations of an electric quantity from one or more predetermined values are detected at the output of the system and fed back to a device within the system to restore the detected quantity to its predetermined value or values, i.e. retroactive systems
    • G05F1/10Regulating voltage or current
    • G05F1/12Regulating voltage or current wherein the variable actually regulated by the final control device is ac
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0492Patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/08Arrangements or circuits for monitoring, protecting, controlling or indicating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002Cancer treatment, e.g. tumour
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals

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  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Electrotherapy Devices (AREA)

Abstract

The invention provides a frequency adjusting device, a frequency adjusting method and an electric field therapeutic apparatus, wherein a control module in the frequency adjusting device is used for generating a control instruction; the signal generation module is used for generating an alternating current signal in a specific frequency range according to the control instruction and applying the alternating current signal to an electrode slice attached to a target human body; the signal detection module is used for detecting the current value data flowing through the electrode plate and transmitting the current value data to the control module; the control module is also used for determining the optimal treatment frequency which is adapted to the target human body according to the current value data so that the signal generation module can carry out frequency adjustment based on the optimal treatment frequency. It is known that, for different target human bodies, the corresponding detected current value data flowing through the electrode plate is different, and the optimal treatment frequency determined by the current value data can meet the treatment requirement of the target human body to a greater extent, so that the overall treatment effect is better.

Description

Frequency adjusting device and method and electric field therapeutic apparatus
Technical Field
The invention relates to the technical field of medical equipment, in particular to a frequency adjusting device and method and an electric field therapeutic apparatus.
Background
The electric field therapy is a therapy implemented by a portable and noninvasive medical instrument, and the basic principle is established on the basis of the mitosis obstruction of an electric field to tumor cells, and the different frequencies, the different directions and the different intensities of the electric field all show different tumor inhibition effects.
The existing tumor electric field therapeutic apparatus mainly comprises a signal generator and an electrode plate. During electric field therapy, the signal generator generates electric field energy that is distributed to electrode pads that couple the electric field energy into the body to apply an alternating electric field to the tissue region where the tumor is located.
The current tumor treatment electric field technology generally adopts a uniform alternating electric field, when tumor cells are in late stage and end stage in mitosis, a geometric structure 'cleavage ditch' playing a key role appears in the center of one cell when the cell is about to divide into two sub-cells, and a current line generated by applying an electric field enters from one pole of the sub-cells, is highly concentrated in the cleavage ditch and passes out from the other pole of the cell. The organelles guided by the current lines aggregate towards the cleavage groove, causing the membrane pressure there to rise and eventually the cells to break from the cleavage groove due to the "hammering effect". In particular, the electric field direction can only disrupt cell division if it is parallel to the long axis of cell division.
During the actual treatment, the following situations exist: the tumor cells of the patients are not of the same size. Tumor cells of each size will have a fixed frequency range of sensitivity, where frequency range of sensitivity refers to the frequency of the electric field applied to the tumor cells, if within the range of sensitivity there is a significant inhibition of tumor cell growth.
In the related art, for convenience of operation, electric field energy is often generated by selecting application of a certain fixed frequency signal within the sensitive frequency range. However, the internal environments of different human bodies are different, even if the internal environments of the same human body are different in different periods, for example, corresponding changes can be generated in the process of impedance re-treatment of the internal environments, and if the treatment is carried out by adopting fixed frequency for tumor cells with different sizes or the same human body or different human bodies under different environments in the treatment process, the treatment effect can be greatly reduced.
Disclosure of Invention
The embodiment of the invention at least provides a frequency adjusting device, a frequency adjusting method and an electric field therapeutic apparatus, so that the optimal therapeutic frequency suitable for different human bodies is determined through frequency adjustment, and the therapeutic effect is improved.
In a first aspect, an embodiment of the present invention provides a frequency adjustment apparatus, including: the device comprises a control module, a signal generation module and a signal detection module, wherein the signal detection module and the signal generation module are electrically connected with the control module;
the control module is used for generating a control instruction which is used for controlling the signal generation module to generate an alternating current signal in a specific frequency range;
the signal generation module is used for generating an alternating current signal in a specific frequency range according to the control instruction and applying the alternating current signal to an electrode sheet attached to a target human body;
the signal detection module is used for detecting current value data flowing through the electrode plate and transmitting the current value data to the control module;
the control module is further used for determining an optimal treatment frequency adapted to the target human body according to the current value data, so that the signal generation module carries out frequency adjustment based on the optimal treatment frequency.
In one possible implementation manner, the signal generating module comprises a signal generating unit and a signal modulating unit;
the signal generating unit is used for generating a carrier signal taking the optimal treatment frequency as a central frequency and generating a modulation signal with a preset modulation frequency;
the signal modulation unit is used for modulating the carrier signal based on the modulation signal to obtain a modulated signal.
In one possible implementation, the current value data includes a range of current values corresponding to the particular frequency range; the control module is specifically configured to determine an optimal treatment frequency adapted to the target human body according to the following steps:
determining a maximum current region segment from the current value range;
and determining the frequency corresponding to the maximum current value in the maximum current area section as the optimal treatment frequency.
In a possible embodiment, the signal generating module is specifically configured to generate an ac signal in a specific frequency range according to the following steps:
determining a frequency interval and a time interval for outputting the alternating current signal according to the control instruction;
and generating an alternating current signal with a specific frequency range according to the frequency interval and the time interval.
In one possible embodiment, the method further comprises: a power module;
the power supply module is used for directly supplying power to the control module, the signal generation module and the signal detection module respectively.
In a second aspect, the present invention further provides a frequency adjustment method, which is applied to the frequency adjustment device in any one of the first aspect and its various embodiments, the method including:
acquiring a control instruction, wherein the control instruction is used for controlling the signal generation module to generate an alternating current signal in a specific frequency range;
receiving current value data which is detected by a signal detection module and flows through the electrode plate, wherein the current value data is obtained based on the fact that the signal generation module applies the generated alternating current signal to the electrode plate attached to a target human body;
and determining an optimal treatment frequency adapted to the target human body according to the current value data, so that the signal generation module carries out frequency adjustment based on the optimal treatment frequency.
In a possible embodiment, the current value data includes a current value range corresponding to the specific frequency range, and the determining an optimal treatment frequency adapted to the target human body according to the current value data includes:
determining a maximum current region segment from the current value range;
and determining the frequency corresponding to the maximum current value in the maximum current area section as the optimal treatment frequency.
In one possible embodiment, the method for causing the signal generation module to perform frequency adjustment based on the optimal treatment frequency includes:
determining a first location coordinate indicated by a maximum current value in the maximum current region segment;
determining a second position coordinate corresponding to the preset treatment frequency;
determining a frequency difference based on a coordinate difference between the first location coordinate and the second location coordinate;
and adjusting the preset treatment frequency based on the frequency difference value to obtain the optimal treatment frequency.
In a second aspect, the present invention further provides an electric field therapeutic apparatus, which is characterized by comprising an electrode sheet, and the frequency adjustment device of the first aspect and any of its various embodiments.
The frequency adjusting device, the frequency adjusting method and the electric field therapeutic apparatus are adopted, and the frequency adjusting device comprises a control module for generating a control instruction; the signal generation module is used for generating an alternating current signal in a specific frequency range according to the control instruction and applying the alternating current signal to an electrode slice attached to a target human body; the signal detection module is used for detecting the current value data flowing through the electrode plate and transmitting the current value data to the control module; the control module is also used for determining the optimal treatment frequency which is adapted to the target human body according to the current value data. It is known that, for different target human bodies, the detected current value data flowing through the electrode plate is different, and the optimal treatment frequency determined by the current value data can meet the treatment requirement of the target human body to a greater extent.
Other advantages of the present invention will be explained in more detail in connection with the following description and accompanying drawings.
It should be understood that the foregoing description is only an overview of the technical solutions of the present invention, so that the technical means of the present invention may be more clearly understood and implemented in accordance with the content of the specification. The following specific embodiments of the present invention are described in order to make the above and other objects, features and advantages of the present invention more comprehensible.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are necessary for the embodiments to be used are briefly described below, the drawings being incorporated in and forming a part of the description, these drawings showing embodiments according to the present invention and together with the description serve to illustrate the technical solutions of the present invention. It is to be understood that the following drawings illustrate only certain embodiments of the invention and are therefore not to be considered limiting of its scope, for the person of ordinary skill in the art may admit to other equally relevant drawings without inventive effort. Also, like reference numerals are used to designate like parts throughout the figures. In the drawings:
FIG. 1 shows a schematic block diagram of an electric field therapeutic apparatus according to an embodiment of the present invention;
fig. 2 shows a schematic block diagram of a frequency adjustment device according to an embodiment of the present invention;
fig. 3 shows a schematic diagram of an electric field therapeutic apparatus according to an embodiment of the present invention;
fig. 4 is a flowchart of a frequency adjustment method according to an embodiment of the present invention;
fig. 5 is a flowchart illustrating a specific method for adjusting a carrier center frequency in the frequency adjustment method according to the embodiment of the present invention.
Detailed Description
Exemplary embodiments of the present invention will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present invention are shown in the drawings, it should be understood that the present invention may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.
In describing embodiments of the present invention, it will be understood that terms, such as "comprises" or "comprising," and the like, are intended to indicate the presence of features, numbers, steps, acts, components, portions, or combinations thereof, that are invented in this specification, and are not intended to exclude the possibility of the presence of one or more other features, numbers, steps, acts, components, portions, or combinations thereof.
Unless otherwise indicated, "/" means or, e.g., A/B may represent A or B; "and/or" herein is merely an association relationship describing an association object, and means that three relationships may exist, for example, a and/or B may mean: a exists alone, A and B exist together, and B exists alone.
The terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first", "a second", etc. may explicitly or implicitly include one or more such feature. In the description of the embodiments of the present invention, unless otherwise indicated, the meaning of "a plurality" is two or more.
It has been found that in the related art, electric field energy is often generated by application of a fixed frequency signal for tumor treatment. The prolonged use of a fixed frequency will cause the cancer cells to develop "drug resistance" and thus reduce the effective therapeutic effect. And because the frequency of sensitivity is different for each patient's cancer cells, if only one frequency of treatment is used, this will result in a condition that is ineffective for some patients. In addition, since the internal environment of the human body is not constant, the impedance value is also changed and is in a dynamic balance, the sensitive frequency tested at a certain time is only the sensitive frequency in the internal environment of that time period, and if the tumor therapeutic apparatus is always used for treating at a sensitive frequency, the therapeutic effect is affected.
In one solution in the prior art, the therapeutic effect is adjusted by adjusting the amplitude of the alternating current, i.e. the carrier signal frequency is high and constant, but the signal amplitude varies with the fundamental signal; however, amplitude modulation techniques have a number of drawbacks, such as amplitude modulation methods reduce the voltage amplitude of the signal, which correspondingly reduces the effective field strength applied to the patient's body, thereby affecting the effective therapeutic effect of the patient; and weak anti-interference capability, low power utilization rate, etc.
To at least partially address one or more of the above-mentioned problems, as well as other potential problems, the present invention provides at least one frequency adjustment scheme based on frequency dynamic adjustment to determine an optimal treatment frequency for a human body, which significantly improves the treatment effect.
Compared with the amplitude modulation technology, the frequency modulation technology provided by the invention has a plurality of obvious advantages: firstly, the anti-interference capability of frequency modulation is stronger than that of amplitude modulation, the difference between the frequency modulation and the amplitude modulation is that parasitic amplitude modulation generated can be eliminated through a limiting method specific to the frequency modulation, and the amplitude modulation cannot be used because an amplitude-modulated signal is changed, meanwhile, the higher the signal-to-noise ratio of the signal is, the stronger the anti-interference degree of the signal is, the signal-to-noise ratio of the signal obtained after demodulation is related to a modulation coefficient, the larger the modulation coefficient is, the larger the signal-to-noise ratio is, and the coefficient of the frequency modulation is far greater than that of the amplitude modulation, so the amplitude modulation is inferior; the second is that the bandwidth of the frequency modulation wave is higher than that of the amplitude modulation wave, the carrier wave of the amplitude modulation wave is a fixed frequency, the amplitude of the amplitude modulation wave only changes along with the modulation signal, the frequency of the frequency modulation wave changes along with the modulation signal, and the bandwidth is 2 times of the frequency of the modulation signal; and thirdly, the frequency modulation power utilization rate is higher, the side frequency power is the effective power for transmitting the modulation signal in the total transmission power, the side frequency power is related to the modulation coefficient, the modulation coefficient is large, the side frequency power is large, and the power utilization rate is better than that of the side frequency power.
For the convenience of understanding the embodiments of the present invention, the electric field therapeutic apparatus provided in the embodiments of the present invention will be described in detail. Referring to fig. 1, a schematic diagram of an electric field therapeutic apparatus according to an embodiment of the present invention is shown, where the electric field therapeutic apparatus mainly includes a frequency adjustment device 11 and an electrode plate 22.
The frequency adjustment device 11 can solve the problem of "drug resistance" of cancer cells generated by a fixed frequency by applying signals in a specific frequency range and the problem of low treatment effect caused by different sensitive frequencies due to individual differences and differences of internal environments, and can increase effective treatment field intensity by adjusting the center frequency point with optimal treatment effect in real time by monitoring current applied to the electrode sheet 22 on the target human body. Besides, the frequency modulation technology can solve the problem of electric field intensity attenuation in an amplitude modulation mode and the problem of poor anti-interference capability.
The signal related to the specific frequency range may be based on the signal generation module in the frequency adjustment device 11, for example, the specific frequency adjustment range may be 100KHZ-300KHZ, which mainly considers that the frequency range is a frequency range that is more effective in tumor treatment, and further considers that each size of tumor cell has a fixed sensitive frequency range, based on which the frequency adjustment range may be a range that dynamically changes with the size of the tumor cell, so that the frequency adjustment range may be within the sensitive frequency range regardless of the tumor size, thereby having an obvious inhibition effect on tumor cell growth. Meanwhile, the center frequency point with the optimal therapeutic effect determined by the frequency adjustment scheme provided by the embodiment of the invention can be the optimal therapeutic frequency falling in the sensitive frequency range, and the effective therapeutic field is stronger, so that the therapeutic effect is remarkably improved.
In addition, the step of the relevant signals and the duration of the corresponding frequencies can be determined based on different treatment requirements, for example, 1KHZ step, 100KHZ to 300KHZ output, 3 seconds of each frequency output, and other frequency output setting manners are not particularly limited herein.
The frequency adjustment device 11 is a key component of the electric field therapeutic apparatus, and the operation principle of the frequency adjustment device 11 will be described with emphasis.
As shown in fig. 2, the frequency adjustment device 11 provided in the embodiment of the present invention mainly includes a control module 111, a signal generating module 112, and a signal detecting module 113, where the signal detecting module 113 and the signal generating module 112 are electrically connected to the control module 111;
a control module 111 for generating a control instruction for controlling the signal generation module 112 to generate an ac signal in a specific frequency range;
a signal generation module 112 for generating an ac signal of a specific frequency range according to the control instruction and applying the ac signal to an electrode pad attached to a target human body;
a signal detection module 113 for detecting current value data flowing through the electrode sheet and transmitting the current value data to the control module 111;
the control module 111 is further configured to determine an optimal treatment frequency adapted to the target human body according to the current value data, so that the signal generating module 112 performs frequency adjustment based on the optimal treatment frequency.
In order to facilitate understanding of the frequency adjustment device 11 provided in the embodiment of the present invention, a simple description is first provided for an application scenario of the device. The frequency adjustment device 11 according to the embodiments of the present invention may be mainly applied in the field of electric field therapy, and in particular may be adapted to electrode pads to form alternating electric field signals for the treatment of tumors.
In this case, the frequency adjustment device 11 may be provided in the host device, and in this case, when a socket is provided in the host device, the socket may be used as a signal output terminal and may act on an electrode sheet to be applied to a human body. In practical applications, the frequency adjustment device 11 may be applied to the electric field therapeutic apparatus in other ways, which is not limited herein.
Considering that the signals with fixed frequency are correspondingly generated in the related art, which cannot achieve a good therapeutic effect, a frequency adjustment scheme for automatically determining the optimal therapeutic frequency adapted to the target human body by combining the coordination of the control module 111, the signal generation module 112 and the signal detection module 113 is provided, so as to remarkably improve the therapeutic effect.
Considering that the optimal treatment frequencies (corresponding to resonance frequency points) actually required by different human bodies in different periods are different, for example, for middle-stage and later-stage tumor patients, a higher treatment frequency may be required, and for early-stage tumor patients, a general treatment frequency is sufficient to achieve a good treatment effect, so that in the frequency adjustment scheme provided by the embodiment of the invention, dynamic frequency adjustment in a specific frequency range is required to be performed on a target human body to determine an adaptive optimal treatment frequency.
The specific frequency range may be a frequency range determined according to the therapeutic requirement, and the specific frequency range may be referred to in the above description, for example, 100KHZ-300KHZ, which is not described herein. In addition, the frequency interval and the time interval of the output signal can be predetermined according to the control command, the frequency interval corresponds to the step, the time interval corresponds to the frequency duration, generally, the same time can be continuously acted on different frequency points, so as to avoid the influence of the time factor on the subsequent determination of the optimal treatment frequency, and then the alternating current signal in the specific frequency range can be generated based on the signal output parameters.
In order to determine an optimal treatment frequency adapted to different human bodies, the optimal treatment frequency is a sub-frequency range or a specific frequency within the specific frequency range; the signal generating module 112 may generate an ac signal in the specific frequency range under the control of the control module 111, and after the ac signal is applied to the electrode patch applied to the target human body, current detection may be performed based on the signal detecting module 113, which mainly considers that the sensitivity of different human bodies to relevant frequency points in the specific frequency range is different, and the closer to the resonance frequency point, the smaller the capacitive reactance is, which can be fully reflected in the detected current value data, so that an optimal treatment frequency adapted to the target human body may be determined, and the greater the field intensity reaching the target position (such as the application center position) is, the better the treatment effect is.
The current detection herein is a detection for a specific frequency range, and generally, the current is not in a linear relationship with frequency, and the larger the frequency is, the larger the current is, and the larger the voltage is, but in the case of the same voltage value, the largest current value (because the capacitive reactance is smallest) when the frequency matching with the tumor cell (i.e., resonance frequency point) is applied, so that the current value range corresponding to the specific frequency range can be determined based on the current detection, and then the center point of the region where the current value is largest can be further determined, and then the center frequency point having the best therapeutic effect (i.e., the best therapeutic frequency) can be determined.
In the embodiment of the invention, the maximum current area section can be determined from the current value range, and then the frequency corresponding to the maximum current value in the maximum current area section is determined as the optimal treatment frequency.
Although the applied frequency and the detected current value are not in a linear relationship, there is a one-to-one correspondence between the applied frequency and the detected current value, and when the current value ranges corresponding to all the current values are determined, the maximum current area section may be selected based on the vicinity of the upper limit of the current value range.
Here, in order to further enhance the therapeutic effect, the signal generating module 112 in the frequency adjustment device 11 provided in the embodiment of the present invention may include a signal generating unit and a signal modulating unit, where:
a signal generating unit for generating a carrier signal with an optimal treatment frequency as a center frequency and generating a modulation signal with a preset modulation frequency;
and the signal modulation unit is used for modulating the carrier signal based on the modulation signal to obtain a modulated signal.
In the course of applying the optimal treatment frequency to the electrode plate, the signal generating unit may generate, on the one hand, a carrier signal centered at the optimal treatment frequency for suppressing and destroying tumor cells, and on the other hand, a modulation signal of a preset modulation frequency for limiting the frequency range of the carrier signal, i.e. the carrier signal bandwidth.
In the embodiment of the invention, the effective limitation of the frequency range may further improve the treatment effect, which mainly considers that the frequency near the optimal treatment frequency generally has better treatment effect, and the problem of drug resistance caused by long-time fixed frequency is further avoided on the premise of ensuring the treatment effect by small-amplitude frequency fluctuation.
The limitation of the frequency range is not too wide or too narrow, and the frequency range is too narrow, so that the action time of each frequency point is longer and cannot relate to other effective frequency points, and the action time of each frequency point is shorter and cannot achieve the continuous effective treatment effect, therefore, the embodiment of the invention can select a proper frequency range based on different treatment requirements, for example, in the case that the center frequency of a carrier signal is fp, frequency modulation of 1KHZ can be performed, that is, the frequency of the modulated signal corresponds to fp+/-1 KHZ.
The frequency adjustment device 11 provided in the embodiment of the present invention may further include a power module 114 that directly supplies power to the control module 111, the signal generating module 112, and the signal detecting module 113, where the specific power supply mode is not limited in particular.
Here, in order to further understand the working principle of the frequency adjustment device 11 provided in the embodiment of the present invention, the structure of the tumor electric field therapeutic apparatus shown in fig. 3 may be further described.
As shown in fig. 3, the tumor electric field therapeutic apparatus based on the frequency modulation mode provided by the embodiment of the invention includes 5 modules: 1. a micro control unit (Microcontroller Unit, MCU) control module; 2. a power module; 3. a signal detection module; 4. an electrode sheet; 5. and a signal generating and modulating module.
The MCU control module sends a control instruction to the signal generation and modulation module through the serial port to generate sine wave signals with specific frequency (default 100-300 KHZ) and voltage (peak value 100V) to be applied to the electrode plate; the electrode plates are used as electric field transducers and are attached to a human body, and comprise more than two pairs of electrode plates; the signal detection module detects the current signal flowing through the electrode plate, so as to adjust the center frequency in the signal generation and modulation module.
The power supply module supplies power to the MCU control module, the signal detection module and the signal generation and modulation module, wherein the voltages input to the MCU control module and the signal detection module can be the same and 3.3V, and the voltages input to the signal generation and modulation module can be different and respectively 3.3V and +/-50V; the signal detection module is used for detecting the current in the electrode plate, transmitting the current value data to the MCU control module through the serial port, judging the current value data received by the signal detection module by the MCU control module, obtaining a current maximum value area section, obtaining the optimal treatment frequency fp, and sending an instruction to adjust the central frequency in the signal generation and modulation module to fp.
After the frequency adjustment, the signal generating and modulating module can generate two paths of sine wave signals, one path is a carrier wave signal, the central frequency is fp (for example, 200 KHZ), the voltage is 100V peak value, the other path is a modulating signal, the frequency is 1KHZ, the voltage is 3V peak value, and the signals are output to the electrode plate through modulated frequency modulation waves (for example, 201 KHZ) to carry out subsequent tumor treatment. The frequency of the frequency modulated wave is in a specific frequency range, such as 100KHZ-300KHZ.
In the description of the present specification, reference to the terms "some possible embodiments," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiments or examples is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms are not necessarily directed to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, the various embodiments or examples described in this specification and the features of the various embodiments or examples may be combined and combined by those skilled in the art without contradiction.
With respect to the method flow diagrams of embodiments of the invention, certain operations are described as distinct steps performed in a certain order. Such a flowchart is illustrative and not limiting. Some steps described herein may be grouped together and performed in a single operation, may be partitioned into multiple sub-steps, and may be performed in an order different than that shown herein. The various steps illustrated in the flowcharts may be implemented in any manner by any circuit structure and/or tangible mechanism (e.g., by software running on a computer device, hardware (e.g., processor or chip implemented logic functions), etc., and/or any combination thereof).
Based on the same inventive concept, the embodiment of the present invention further provides a frequency adjustment method corresponding to the frequency adjustment device, and since the principle of solving the problem by the method in the embodiment of the present invention is similar to that of the frequency adjustment device in the embodiment of the present invention, the implementation of the method may refer to the implementation of the device, and the repetition is omitted.
Referring to fig. 4, a flowchart of a frequency adjustment method according to an embodiment of the present invention is shown, and the method is applied to the frequency adjustment device provided in the foregoing embodiment, where the method includes steps S401 to S403, where:
s401: acquiring a control instruction, wherein the control instruction is used for controlling the signal generation module to generate an alternating current signal in a specific frequency range;
s402: receiving current value data, which is detected by the signal detection module and flows through the electrode plate, wherein the current value data is obtained by applying the generated alternating current signal to the electrode plate attached to the target human body based on the signal generation module;
s403: and determining the optimal treatment frequency adapted to the target human body according to the current value data, so that the signal generation module carries out frequency adjustment based on the optimal treatment frequency.
By adopting the frequency adjustment method, a control instruction for controlling the signal generation module to generate an alternating current signal in a specific frequency range is acquired; the current value data of the electrode plate, which is obtained by detection of the receiving signal detection module, flows through the electrode plate; and determining the optimal treatment frequency adapted to the target human body according to the current value data, so that the signal generation module carries out frequency adjustment based on the optimal treatment frequency. It is known that, for different target human bodies, the detected current value data flowing through the electrode plate is different, and the optimal treatment frequency determined by the current value data can meet the treatment requirement of the target human body to a greater extent.
In one possible embodiment, the current value data includes a current value range corresponding to a specific frequency range, and determining an optimal treatment frequency adapted to the target human body from the current value data includes:
determining a maximum current region segment from a range of current values;
and determining the frequency corresponding to the maximum current value in the maximum current area section as the optimal treatment frequency.
In one possible implementation, determining the frequency corresponding to the maximum current value in the maximum current region segment as the optimal treatment frequency, causing the signal generation module to perform frequency adjustment based on the optimal treatment frequency includes:
establishing a current-frequency coordinate system by taking the current value as an x-axis coordinate and taking a frequency value corresponding to the current value as a y-coordinate;
determining a first position coordinate (x 1 、y 1 ) And determining a preset treatment frequency f 0 Corresponding second position coordinates (x 2 、y 2 );
Determining a frequency difference Δf based on a y-axis coordinate value difference between the first and second position coordinates;
the frequency difference Δf is calculated as follows:
Δf=y 2 -y 1
and adjusting the preset treatment frequency based on the frequency difference value to obtain the optimal treatment frequency f.
The optimal treatment frequency f is calculated as follows:
f=(f 0 +Δf)。
in one possible implementation, determining the frequency corresponding to the maximum current value in the maximum current region segment as the optimal treatment frequency, causing the signal generation module to perform frequency adjustment based on the optimal treatment frequency includes:
establishing a frequency-current coordinate system by taking the current value as a y-axis coordinate and taking a frequency value corresponding to the current value as an x-axis coordinate;
determining a first position coordinate (x 1 、y 1 ) And determining a preset treatment frequency f 0 Corresponding second position coordinates (x 2 、y 2 );
Determining a frequency difference Δf based on an x-axis coordinate value difference between the first and second position coordinates;
the frequency difference Δf is calculated as follows:
Δf=x 2 -x 1
and adjusting the preset treatment frequency based on the frequency difference value to obtain the optimal treatment frequency f.
The optimal treatment frequency f is calculated as follows:
f=(f 0 +Δf0
it will be appreciated that the signal generation module outputs an alternating electric field based on the updated optimal treatment frequency f.
It can be appreciated that the optimal treatment frequency is constantly changing due to the constantly changing internal environment of the human body; therefore, the first position coordinate (x) indicated by the maximum current value in the maximum current region segment can also be determined 1 、y 1 ) And a third position coordinate (x 3 、y 3 ) And adjusts the current output optimal treatment frequency f according to the difference of the corresponding coordinates between the two position coordinates.
To further illustrate the adjustment logic regarding the optimal treatment frequency (i.e., the center frequency of the carrier signal), the following description may be provided in conjunction with the flow chart of fig. 5.
As shown in fig. 5, after the electric field therapeutic apparatus completes the system initialization, the control module may send a control command to the signal generating and modulating module, where the default output has a center frequency of 200KHZ, and a maximum current value within a period of time is obtained according to the current detection result of the signal detecting module, so as to obtain the coordinate position of the maximum current value on the frequency-current coordinate axis and obtain the coordinate position of 200KHZ on the frequency-current coordinate axis. Then, a coordinate difference X between the maximum value of the current and 200KHZ in the frequency-current coordinate axis is calculated, when X is 0, the adjustment is not needed, when X is not 0, the adjustment is needed, and the adjustment of the corresponding frequency is carried out according to the size of the coordinate difference X, so that the adjustment logic of the whole carrier frequency is completed.
In an alternative embodiment, the first frequency adjustment is made for a period of time after the device is started, and the output is then made at the adjusted optimal treatment frequency f.
In another alternative embodiment, the device is activated with frequency adjustment at intervals. The interval time can be 6h, 8h or 12h. It should be noted that, the device in the embodiment of the present invention may implement each process of the embodiment of the foregoing method and achieve the same effects and functions, which are not described herein again.
The embodiments of the present invention are described in a progressive manner, and the same and similar parts of the embodiments are referred to each other, and each embodiment is mainly described as a difference from other embodiments. In particular, for apparatus, devices and computer readable storage medium embodiments, the description thereof is simplified as it is substantially similar to the method embodiments, as relevant points may be found in part in the description of the method embodiments.
The apparatus, the device, and the computer readable storage medium provided in the embodiments of the present invention are in one-to-one correspondence with the methods, and therefore, the apparatus, the device, and the computer readable storage medium also have similar advantageous technical effects as the corresponding methods, and since the advantageous technical effects of the methods have been described in detail above, the advantageous technical effects of the apparatus, the device, and the computer readable storage medium are not repeated herein.
It will be apparent to those skilled in the art that embodiments of the present invention may be provided as a method, apparatus (device or system), or computer readable storage medium. Accordingly, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment or an embodiment combining software and hardware aspects. Furthermore, the invention may take the form of a computer-readable storage medium embodied in one or more computer-usable storage media (including, but not limited to, disk storage, CD-ROM, optical storage, etc.) having computer-usable program code embodied therein.
The present invention is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (devices or systems) and computer-readable storage media according to embodiments of the invention. It will be understood that each flow and/or block of the flowchart illustrations and/or block diagrams, and combinations of flows and/or blocks in the flowchart illustrations and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including instruction means which implement the function specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
In one typical configuration, a computing device includes one or more processors (CPUs), input/output interfaces, network interfaces, and memory.
The memory may include volatile memory in a computer-readable medium, random Access Memory (RAM) and/or nonvolatile memory, such as Read Only Memory (ROM) or flash memory (flash RAM). Memory is an example of computer-readable media.
Computer readable media, including both non-transitory and non-transitory, removable and non-removable media, may implement information storage by any method or technology. The information may be computer readable instructions, data structures, modules of a program, or other data. Examples of storage media for a computer include, but are not limited to, phase change memory (PRAM), static Random Access Memory (SRAM), dynamic Random Access Memory (DRAM), other types of Random Access Memory (RAM), read Only Memory (ROM), electrically Erasable Programmable Read Only Memory (EEPROM), flash memory or other memory technology, compact disc read only memory (CD-ROM), digital Versatile Discs (DVD) or other optical storage, magnetic cassettes, magnetic tape magnetic disk storage or other magnetic storage devices, or any other non-transmission medium, which can be used to store information that can be accessed by a computing device. Furthermore, although the operations of the methods of the present invention are depicted in the drawings in a particular order, this is not required to either imply that the operations must be performed in that particular order or that all of the illustrated operations be performed to achieve desirable results. Additionally or alternatively, certain steps may be omitted, multiple steps combined into one step to perform, and/or one step decomposed into multiple steps to perform.
While the spirit and principles of the present invention have been described with reference to several particular embodiments, it is to be understood that the invention is not limited to the particular embodiments of the invention nor does it imply that features in the various aspects are not useful in combination, nor are they intended to be useful in any way, such as for convenience of description. The invention is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the appended claims.

Claims (9)

1. A frequency adjustment device, comprising: the device comprises a control module, a signal generation module and a signal detection module, wherein the signal detection module and the signal generation module are electrically connected with the control module;
the control module is used for generating a control instruction which is used for controlling the signal generation module to generate an alternating current signal in a specific frequency range;
the signal generation module is used for generating an alternating current signal in a specific frequency range according to the control instruction and applying the alternating current signal to an electrode sheet attached to a target human body;
the signal detection module is used for detecting current value data flowing through the electrode plate and transmitting the current value data to the control module;
the control module is further used for determining an optimal treatment frequency adapted to the target human body according to the current value data, so that the signal generation module carries out frequency adjustment based on the optimal treatment frequency.
2. The apparatus of claim 1, wherein the signal generation module comprises a signal generation unit and a signal modulation unit;
the signal generating unit is used for generating a carrier signal taking the optimal treatment frequency as a central frequency and generating a modulation signal with a preset modulation frequency;
the signal modulation unit is used for modulating the carrier signal based on the modulation signal to obtain a modulated signal.
3. The apparatus according to claim 1 or 2, wherein the current value data comprises a current value range corresponding to the specific frequency range; the control module is specifically configured to determine an optimal treatment frequency adapted to the target human body according to the following steps:
determining a maximum current region segment from the current value range;
and determining the frequency corresponding to the maximum current value in the maximum current area section as the optimal treatment frequency.
4. The apparatus according to claim 1 or 2, wherein the signal generating module is adapted to generate the ac signal of the specific frequency range in particular by:
determining a frequency interval and a time interval for outputting the alternating current signal according to the control instruction;
and generating an alternating current signal with a specific frequency range according to the frequency interval and the time interval.
5. The apparatus according to claim 1 or 2, further comprising: a power module;
the power supply module is used for directly supplying power to the control module, the signal generation module and the signal detection module respectively.
6. A frequency adjustment method, characterized in that the method is applied to the frequency adjustment device according to any one of claims 1 to 5, the method comprising:
acquiring a control instruction, wherein the control instruction is used for controlling the signal generation module to generate an alternating current signal in a specific frequency range;
receiving current value data which is detected by a signal detection module and flows through the electrode plate, wherein the current value data is obtained based on the fact that the signal generation module applies the generated alternating current signal to the electrode plate attached to a target human body;
and determining an optimal treatment frequency adapted to the target human body according to the current value data, so that the signal generation module carries out frequency adjustment based on the optimal treatment frequency.
7. The method of claim 6, wherein the current value data includes a current value range corresponding to the particular frequency range, the determining an optimal treatment frequency for the target human based on the current value data comprising:
determining a maximum current region segment from the current value range;
and determining the frequency corresponding to the maximum current value in the maximum current area section as the optimal treatment frequency.
8. The method of claim 7, wherein said causing the signal generation module to perform frequency adjustment based on the optimal treatment frequency comprises:
determining a first location coordinate indicated by a maximum current value in the maximum current region segment;
determining a second position coordinate corresponding to the preset treatment frequency;
determining a frequency difference based on a coordinate difference between the first location coordinate and the second location coordinate;
and adjusting the preset treatment frequency based on the frequency difference value to obtain the optimal treatment frequency.
9. An electric field therapeutic apparatus comprising an electrode sheet, and the frequency adjustment device according to any one of claims 1 to 5.
CN202310497600.2A 2023-05-05 2023-05-05 Frequency adjusting device and method and electric field therapeutic apparatus Pending CN116594456A (en)

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