CN116585436A - Traditional Chinese medicine formula for treating pregnancy residue and annexism cyst, and granule and application thereof - Google Patents

Traditional Chinese medicine formula for treating pregnancy residue and annexism cyst, and granule and application thereof Download PDF

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CN116585436A
CN116585436A CN202310538458.1A CN202310538458A CN116585436A CN 116585436 A CN116585436 A CN 116585436A CN 202310538458 A CN202310538458 A CN 202310538458A CN 116585436 A CN116585436 A CN 116585436A
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traditional chinese
chinese medicine
rhizoma
pregnancy
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董伟
许凌雪
林天东
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Heji Hospital Affiliated To Changzhi Medical College
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Heji Hospital Affiliated To Changzhi Medical College
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Abstract

The invention provides a traditional Chinese medicine formula for treating pregnancy residual and accessory cyst, and granules and application thereof. The traditional Chinese medicine formula comprises the following raw materials in parts by weight: 8-12 parts of cassia twig, 13-17 parts of poria cocos, 8-12 parts of paeonia lactiflora, 8-12 parts of moutan bark, 8-12 parts of peach kernel, 8-12 parts of safflower, 8-12 parts of radix trichosanthis, 8-12 parts of rhizoma sparganii, 8-12 parts of rhizoma curcumae, 8-12 parts of fructus forsythiae, 8-12 parts of stiff silkworm and 8-12 parts of purified pinellia ternate. The traditional Chinese medicine formula not only has the effects of promoting the discharge of the residues of pregnancy, shortening the bleeding time, greatly reducing the defect of abortion after medicine, avoiding influencing pregnancy again, but also can treat accessory cyst, reduce pelvic effusion and the like, and comprehensively improve the health of uterus and accessories of patients.

Description

Traditional Chinese medicine formula for treating pregnancy residue and annexism cyst, and granule and application thereof
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine formula for treating pregnancy residues and annexitis cysts, and granules and application thereof.
Background
With the development of society, the number of miscarriage-requiring patients is increased clinically at present after contraceptive failure, and meanwhile, mifepristone combined with misoprostol medicine is the treatment scheme with the highest frequency of use at present for stopping early pregnancy clinically, the former plays a role in promoting the degeneration and necrosis of the womb decidua, and the later is required to be dominant for strengthening the womb contraction, so that embryos can be discharged according to a given schedule and route pattern in the treatment mode. Through the related report, the two are required to be combined together to achieve the effect of stopping early pregnancy, and the treatment mode has the advantages of high success rate, small wound, low cost, small psychological pressure, easier acceptance than uterine curettage and the like clinically. However, the residual uterine cavity caused by the medical abortion is a main common complication, if no intervention measures are taken in time, the post-abortion decidua appears, the placenta is peeled off slowly or incompletely, and gestational tissues are remained in the uterine cavity, so that the situation often causes infection, irregular vaginal bleeding, intrauterine adhesion, amenorrhea, and even the re-pregnancy of females is affected. The uterine curettage is a common treatment means for uterine cavity residue after medical abortion, has a certain curative effect, but partial patients are afraid of poor treatment coordination degree in uterine curettage, blind uterine curettage is extremely easy to cause incomplete curettage, undetected or excessive uterine curettage, so that residues are not exhausted, or endometrium is damaged, endometrium inflammation is caused, and even complications such as infertility, uterine cavity adhesion and the like are caused. Therefore, the traditional Chinese medicine formula is needed to be provided, and the pregnancy residue can be effectively treated.
Disclosure of Invention
In view of the above, the invention provides a traditional Chinese medicine formula for treating pregnancy residual and accessory cyst, which not only can treat pregnancy residual, but also can treat accessory cyst, and can reduce pelvic effusion and the like.
Etiology and pathogenesis of pregnancy residue after drug abortion: the situation that the residual pregnancy after abortion causes vaginal bleeding can be followed regularly, has the characteristics of larger bleeding amount and longer duration, can be divided into the range of abortion and bleeding in traditional Chinese medicine and can be included in the category of abdominal mass in traditional Chinese medicine, because after abortion, a part of human abdomen has the feeling of falling pain, and the vaginal bleeding is mostly due to abdominal mass. For the disease course of blood stasis and damp retention, it is usually accompanied with deficiency and excess, especially for the pregnant women, it should be used only slowly to dispel the stasis and not be able to attack, otherwise it is easy to damage healthy qi and affect the later pregnancy, so it is indicated for the treatment of blood stasis and mass.
For pregnancy residue after abortion, it is mainly indicated for qi and blood, yin and yang, viscera syndrome differentiation, and it is used to promote blood circulation to remove blood stasis, dredge collaterals and dissipate nodulation. The medicine is used for treating pregnancy residual deficiency and blood stasis after abortion from deficiency tonifying and blood stasis removing. Specifically, gestational residues following drug abortion can be divided into two main categories: firstly, the residual of deficiency of qi and blood or yin and yang; secondly, the blood stasis is a residual. Deficiency of qi and blood, failure to promote the transformation, residual deficiency syndrome, and residual excess syndrome due to qi and blood stasis. The unsmooth blood stasis and the abnormal functioning of uterus are important pathological factors of the disease. According to clinical manifestations, three general categories are: firstly, the residue of deficiency of qi and blood; secondly, the residual of blood stasis; thirdly, the residue of yin and yang deficiency. Clinically, the three syndromes can be independently seen, and the common syndrome is accompanied by the syndrome of inclusion.
The pregnancy residue after medical abortion is mostly seen by deficiency of qi and blood, and clinically manifests as little colporrhagia, pale color, weak quality, listlessness, pale lips and tongue, numbness of hands and feet, etc., and is used for treating blood circulation promoting and stasis resolving, qi tonifying and blood replenishing.
The technical scheme of the invention is realized as follows:
a traditional Chinese medicine formula for treating pregnancy residue and annexism is prepared from the following raw materials in parts by weight: 8-12 parts of cassia twig, 13-17 parts of poria cocos, 8-12 parts of paeonia lactiflora, 8-12 parts of moutan bark, 8-12 parts of peach kernel, 8-12 parts of safflower, 8-12 parts of radix trichosanthis, 8-12 parts of rhizoma sparganii, 8-12 parts of rhizoma curcumae, 8-12 parts of fructus forsythiae, 8-12 parts of stiff silkworm and 8-12 parts of purified pinellia ternate.
Further, the material is prepared from the following raw materials in parts by weight: 10 parts of cassia twig, 15 parts of poria cocos, 10 parts of paeonia lactiflora, 10 parts of cortex moutan, 10 parts of peach kernel, 10 parts of safflower, 10 parts of radix trichosanthis, 10 parts of rhizoma sparganii, 10 parts of rhizoma curcumae, 10 parts of fructus forsythiae, 10 parts of stiff silkworm and 10 parts of rhizoma pinelliae preparata.
Furthermore, the raw materials of the traditional Chinese medicine formula also comprise motherwort herb and rhizoma corydalis; the material is prepared from the following raw materials in parts by weight: 8-12 parts of cassia twig, 13-17 parts of poria cocos, 8-12 parts of paeonia lactiflora, 8-12 parts of moutan bark, 8-12 parts of peach kernel, 8-12 parts of safflower, 8-12 parts of radix trichosanthis, 8-12 parts of rhizoma sparganii, 8-12 parts of rhizoma curcumae, 8-12 parts of fructus forsythiae, 8-12 parts of stiff silkworm, 8-12 parts of rhizoma pinelliae preparata, 8-12 parts of leonurus and 8-12 parts of rhizoma corydalis.
Further, the traditional Chinese medicine formula for treating pregnancy residue and annexism cyst is prepared from the following raw materials in parts by weight: 10 parts of cassia twig, 15 parts of poria cocos, 10 parts of paeonia lactiflora, 10 parts of cortex moutan, 10 parts of peach kernel, 10 parts of safflower, 10 parts of radix trichosanthis, 10 parts of rhizoma sparganii, 10 parts of rhizoma curcumae, 10 parts of fructus forsythiae, 10 parts of stiff silkworm, 10 parts of rhizoma pinelliae preparata, 10 parts of leonurus and 10 parts of rhizoma corydalis.
A Chinese medicinal granule for treating pregnancy residual and annexism is prepared from any one of the Chinese medicinal formulas.
Further, the traditional Chinese medicine granule is prepared from the following raw materials in parts by weight: 10g of cassia twig, 15g of poria cocos, 10g of peony, 10g of cortex moutan, 10g of peach kernel, 10g of safflower, 10g of radix trichosanthis, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 10g of fructus forsythiae, 10g of stiff silkworm and 10g of rhizoma pinelliae preparata.
Further, the traditional Chinese medicine granule is prepared from the following raw materials in parts by weight: 10g of cassia twig, 15g of poria cocos, 10g of paeonia lactiflora, 10g of cortex moutan, 10g of peach kernel, 10g of safflower, 10g of radix trichosanthis, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 10g of fructus forsythiae, 10g of stiff silkworm, 10g of rhizoma pinelliae preparata, 10g of leonurus and 10g of rhizoma corydalis.
The traditional Chinese medicine disclosed by the invention is applied to the preparation of medicines for treating pregnancy residues or/and accessory cysts or/and pelvic effusion.
The cassia twig is sweet and warm in nature, and can warm yang qi of blood vessels, warm and dredge blood vessels, so as to smooth menstrual flow, guide triple energizer, downwards dredge bladder to facilitate urination, and promote qi circulation to promote body fluid, so that the medicine is monarch drug; paeonia lactiflora nourishes yin and blood, harmonizes nutrient qi, and can relieve spasm and pain; semen Persicae has effects of promoting blood circulation, removing blood stasis, removing abdominal mass, and assisting principal drug in removing blood stasis; poria has effects of regulating stomach, invigorating spleen, removing dampness, benefiting waist and umbilical qi, and benefiting spleen and qi, and can be used for recovering spleen and stomach function after abortion, with the combination of the two medicines, promoting blood circulation, removing blood stasis, promoting diuresis, eliminating dampness, eliminating phlegm, invigorating spleen, invigorating stomach, tranquilizing mind, removing mass, with the combination of ramulus Cinnamomi, enhancing phlegm and promoting diuresis, and respectively assisting principal drug in removing mass from blood stasis and phlegm dampness; cortex moutan and radix Paeoniae are bitter and slightly cold in flavor, and their blood-activating effects are beneficial to each other in eliminating mass, blood-nourishing and blood-cooling effects, and the pathology of no generation of new blood and long-term heat-dissipating due to blood stasis is taken as adjuvant drug; the rhizoma sparganii, the rhizoma curcumae zedoariae, the radix trichosanthis, the purified pinellia tuber, the stiff silkworm, the fructus forsythiae, the cortex moutan and the radix paeoniae alba are added into the prescription and are used as adjuvant drugs, the rhizoma sparganii and the rhizoma curcumae break blood and promote qi circulation, remove food retention and relieve pain, the radix trichosanthis activates blood and removes stasis, kills embryo and removes miscarriage, the purified pinellia tuber eliminates phlegm and removes food retention, the stiff silkworm eliminates wind and eliminates phlegm and removes stasis, the fructus forsythiae is used with the purified pinellia tuber to strengthen phlegm and remove stasis, the fructus forsythiae is used for removing heat and cooling blood and removing stasis, the safflower activates blood and removes stasis, and the effects of activating blood and removing stasis and relieving mass are achieved together, so that intracellular residues can be promoted to be discharged along with blood stasis.
Furthermore, based on the recipe, motherwort and corydalis tuber are added, the motherwort activates blood circulation to remove blood stasis, contracts the uterine lower fetus, and the corydalis tuber improves the abdominal pain, thereby better treating the pregnancy residual with the abdominal pain.
Compared with the prior art, the invention has the beneficial effects that:
(1) The traditional Chinese medicine formula disclosed by the invention not only has the effects of promoting the discharge of pregnancy residues, shortening the bleeding time, greatly reducing the defect of abortion after medicine, avoiding influencing pregnancy again and improving the uterine health of patients.
(2) By adopting the traditional Chinese medicine formula, the effect is remarkable, and the traditional Chinese medicine granule can reduce the viscosity of whole blood to an ideal state by pharmacological research, has good anti-inflammatory effect, and can better prevent and treat endometrial infection; secondly, the method can enhance the immunity of the organism of the patient; can achieve good effects of calming, relieving pain and stopping bleeding.
(3) From the results of clinical observation, the medicine has good effect of reducing the bleeding time, and the value and the significance are obvious, especially for the situation that the uterine involution after scar uterine medicine flow does not reach the expectations.
(4) The traditional Chinese medicine formula disclosed by the invention not only can treat the residual of pregnancy, but also can treat accessory cysts, can reduce pelvic effusion and the like, and comprehensively improves the uterus and accessory health of patients.
Drawings
FIG. 1 is an image of an ultrasound diagnostic report before treatment of case 1;
fig. 2 is an ultrasound diagnostic report image after case 1 treatment.
FIG. 3 is an image of an ultrasound diagnostic report before treatment of case 2;
fig. 4 is an ultrasound diagnostic report image after case 2 treatment.
FIG. 5 is an image of an ultrasound diagnostic report before treatment of case 3;
fig. 6 is an ultrasound diagnostic report image after case 3 treatment.
FIG. 7 is an image of an ultrasound diagnostic report before treatment of case 4;
fig. 8 is an ultrasound diagnostic report image after case 4 treatment.
FIG. 9 is an image of an ultrasound diagnostic report before treatment of case 5;
fig. 10 is an ultrasound diagnostic report image after case 5 treatment.
FIG. 11 is an image of an ultrasound diagnostic report before treatment of case 6;
fig. 12 is an ultrasound diagnostic report image after case 6 treatment.
Detailed Description
In order to better understand the technical content of the present invention, the following provides specific examples to further illustrate the present invention.
The experimental methods used in the embodiment of the invention are conventional methods unless otherwise specified.
Materials, reagents, and the like used in the examples of the present invention are commercially available unless otherwise specified.
EXAMPLE 1 Chinese medicinal granule
Consists of the following traditional Chinese medicine particles: 10g of cassia twig, 15g of poria cocos, 10g of red paeony root, 10g of tree peony bark, 10g of peach seed, 10g of safflower, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 10g of radix trichosanthis, 10g of fructus forsythiae, 10g of stiff silkworm and 10g of purified pinellia tuber.
EXAMPLE 2 Chinese medicinal granule
Consists of the following traditional Chinese medicine particles: 10g of cassia twig, 15g of poria cocos, 10g of red paeony root, 10g of tree peony bark, 10g of peach seed, 10g of safflower, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 10g of radix trichosanthis, 10g of fructus forsythiae, 10g of stiff silkworm and 10g of purified pinellia tuber.
EXAMPLE 3 Chinese medicinal granule
Consists of the following traditional Chinese medicine particles: 12g of cassia twig, 13g of tuckahoe, 8g of red paeony root, 12g of tree peony bark, 8g of peach seed, 12g of safflower, 8g of common burreed rhizome, 12g of zedoary, 8g of mongolian snakegourd root, 12g of weeping forsythia, 8g of stiff silkworm, 12g of purified pinellia tuber, 8g of motherwort herb and 12g of rhizoma corydalis.
EXAMPLE 4 Chinese medicinal granule
Consists of the following traditional Chinese medicine particles: 8g of cassia twig, 17g of tuckahoe, 12g of red paeony root, 8g of tree peony bark, 12g of peach seed, 8g of safflower, 12g of common burreed rhizome, 8g of zedoary, 12g of mongolian snakegourd root, 8g of weeping forsythia, 12g of stiff silkworm, 8g of purified pinellia tuber, 12g of motherwort herb and 8g of rhizoma corydalis.
The traditional Chinese medicine formula is applied to clinic and has good curative effect, and the examples of partial cases are as follows:
1 typical case 1-mainly for treating pregnancy residual, pelvic effusion
By a woman, 32 years old, 4 months and 23 days 2018, the patient can visit the doctor before '1 day of pregnancy residue after drug abortion is found', and the patient complains of self-induced hypodynamia, continuous small amount of bleeding in vagina, and convenient adjustment, and no obvious discomfort exists. A deep and thready pulse, a pale tongue with thin and white coating. 2018-4-23 gynecological examination B ultrasonic display: hypoechoic sounds are visible in the uterine cavity in the range of about 1.1cm, echo-free sacs are visible in the cervix in the size of about 0.4cm, echo-free sacs are visible in the Gong Gengna sacs in the left appendages in the range of about 3.0 x 1.2cm, the uterine cavity is gourd-shaped, and hydrotubation in the oviduct, pelvic cavity visible effusion and depth of about 1.2cm are considered. Considering qi deficiency and blood stasis of a patient, phlegm stagnation blocking uterus, the treatment is mainly to resolve phlegm and dredge collaterals, the granule (10 g of cassia twig, 15g of poria cocos, 10g of red paeony root, 10g of moutan bark, 10g of peach kernel, 10g of safflower, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 10g of radix trichosanthis, 10g of fructus forsythiae, 10g of stiff silkworm and 10g of purified pinellia ternate) 7 doses are given to the patient, 1 dose of the granule is taken after breakfast, the patient is ordered to have discomfort and timely visit, the patient is reevaluated after 1 week, the vagina is interrupted by a small amount of bleeding, the rest is not uncomfortable, the patient is taken for 2 weeks in front, and the patient is reexamined for gynaecology B ultrasonic in 5 months 18 days in 2018: gong Gengna capsule 0.4cm and pelvic effusion 1.0cm. The retention in the uterine cavity of the patient is disappeared, and the pelvic cavity effusion is reduced.
TABLE 1 ultrasound diagnostic report before and after treatment
Remarks: pelvic effusion is physiological effusion with a volume of not more than 1 cm.
2 typical case 2-mainly treating annexic cyst, pelvic effusion
Gu Mou women, 22 years old, 2021, 9 months, 14 days before the "find accessory cyst block 1 day" were treated, the patient complained about abdominal pain in gynaecology were treated, and abdomen examination B ultrasonic showed: the left ovary is internally probed and a tubular structure is arranged in a range of about 3.3cm by 1.3cm, and the depth of the pelvic effusion is about 1.7cm, so that the possibility of hydrotubation is considered. Gynecological operation is recommended. The patient finds our pulse before, and the pulse is wiry and slippery, and the tongue is pale and thin in coating. Patients like plain with the spleen qi, liver depression and qi stagnation, and take qi stagnation and blood stasis into account to form mass. Therefore, the granule (ramulus Cinnamomi 10g Poria 15g radix Paeoniae Rubra 10g cortex moutan 10g semen Persicae 10g flos Carthami 10g rhizoma Sparganii 10g rhizoma Curcumae 10g radix Trichosanthis 10g fructus forsythiae 10g Bombyx Batryticatus 10g rhizoma Pinelliae Preparatum 10 g) of example 1 is administered 1 dose daily with water after breakfast and supper.
The patient was re-diagnosed after 2 weeks, complained of no obvious discomfort, was taken 2 weeks in front of the patient, and was re-examined for gynecological B-mode at 10 months 12 of 2021: obvious abnormalities of uterus and double accessories are not seen. The patient is healed.
TABLE 2 ultrasound diagnostic report before and after treatment
3 typical case 3-indication of annex cyst
Zhang Mou, female, 52 years old, visit before 8 months of 2018 12, patient complain of hidden abdominal distending pain, normal urination and defecation, and examination of gynecological B-ultrasonic: the low echo package block is visible behind the uterus, the size is about 5.4cm by 5.4cm, the left accessory is about 2.7cm by 2.7cm, and the round liquid dark area is seen, the left accessory cyst of the patient is considered, the low echo package block is left behind the uterus, and the internal uterine stasis is considered, so the granule (the cassia twig 10g, the poria cocos 15g, the red paeony root 10g, the moutan bark 10g, the peach kernel 10g, the safflower 10g, the rhizoma zedoariae 10g, the radix trichosanthis 10g, the weeping forsythiae capsule 10g, the stiff silkworm 10g, the pinellia ternate 10 g) 14 dose is taken after breakfast and supper water. The patient is re-diagnosed after 2 weeks, abdominal distending pain is relieved, taking the large bag block behind the uterus of the patient into consideration, taking the medicine for a long time, and taking the medicine continuously for 5 weeks by a guardian, wherein obvious discomfort is not complained during the taking, and the gynecological B ultrasonic examination is re-examined in 2019 1 month 24 days: no obvious abnormalities were seen in the uterus and appendages. The patient's bag and accessory cyst have disappeared.
TABLE 3 ultrasound diagnostic report before and after treatment
4 typical case 4-indication of annex cyst
Sun Mou, women, 46 years old, 11 months of 2022, 11 days before "half year of finding accessory cyst block", the patient complains about finding accessory cyst block half year, repeated treatment is invalid, the block gradually increases, gynaecology recommends operation treatment, recourse to our, and examination of gynaecology B ultrasonic show: left appendix 4.9cm x 3.5cm mixed echo nodule. A wiry and slippery pulse with a pale tongue with thin coating. Considering qi stagnation and blood stasis, the mass is caused. Therefore, the granule (ramulus Cinnamomi 10g Poria 15g radix Paeoniae Rubra 10g cortex moutan 10g semen Persicae 10g flos Carthami 10g rhizoma Sparganii 10g rhizoma Curcumae 10g radix Trichosanthis 10g fructus forsythiae 10g Bombyx Batryticatus 10g rhizoma Pinelliae Preparatum 10 g) of example 1 is administered 1 dose daily with water after breakfast and supper. The patient is re-diagnosed after 2 weeks, and the patient is told that the accessory cyst is larger, the patient needs to take about 3 months, the patient takes more than 2 months, and the gynecological B ultrasonic examination is re-performed at 2023, 2 months and 4 days: obvious abnormalities of uterus and double accessories are not seen. The accessory cyst disappears when the patient takes the recipe.
TABLE 4 ultrasound diagnostic report before and after treatment
5 typical cases 5-mainly used for treating pregnancy residual, pelvic effusion
Li Mou, female, 31 years old, was treated before 2022, 7 months and 5 days old for "pregnancy remained 2 weeks after drug abortion", and the following symptoms were: lower abdomen vague pain, small amount of vaginal bleeding, normal urination and defecation, insomnia, slippery pulse, pale tongue with thin and white coating, auxiliary examination: 2022, 7, 5B ultrasonic: the intrauterine near-uterine level is detected and the bulk hyperechoic effect is obtained, the range is about 1.5cm by 1.8cm, the possible retention is considered, the small amount of effusion in the pelvic cavity is considered, and the range is about 1.5cm by 0.9cm. Considering that the patient has deficiency of vital qi and internal resistance of phlegm and blood stasis after taking medicine, the treatment takes the effects of activating blood circulation to dissipate blood stasis, dredging collaterals and resolving phlegm as the main part, and the granule (the granule of example 1 is given with 7 doses of cassia twig 10g tuckahoe 15g red paeony root 10g tree peony bark 10g peach kernel 10g safflower 10g common burreed rhizome 10g zedoary 10g mongolian snakegourd root 10g weeping forsythia 10g stiff silkworm 10g purified pinellia tuber 10 g) and 1 dose per day, is taken with water after breakfast and supper, two diagnoses are carried out after one week, the patient complains no colporrhagia, the dull pain of the lower abdomen is relieved, and the B ultrasonic examination is carried out after 7 months in 2022: echo in uterine cavity is uneven, echo is not seen in uterine cavity, and the deepest part of pelvic cavity effusion is about 1.3cm. The patient has disappeared the bulk hyperechoic retentate 1 week after taking the medicine, the effect is not more square, the front 7 doses are taken next, the mucous membrane of the uterine cavity is repaired, and the pelvic effusion is continuously reduced until disappearing.
TABLE 5 ultrasound diagnostic report before and after treatment
6 typical case 6-mainly for pregnancy residue (with abdominal pain)
Ren Mou the female, 32 years old, 10 months and 21 days 2022 mainly because of '20 days with abdominal pain with small vaginal bleeding' before diagnosis, the patient finds that the fetus stops pregnant in obstetric abortion before 20 days, after which the vagina continues to bleed a small amount with dull pain in the lower abdomen, the urination and defecation are regulated, the sleep is easy, the pulse is deep and thin, and the tongue is light and dark and the tongue coating is thin and white. The body is healthy in the past. After 21 days of drug delivery in 2022, the gynecological B-ultrasound examination shows: flocculent echoes are visible in the uterine cavity, approximately 0.46cm wide. Western diagnosis: pregnancy residue after drug abortion, diagnosis in traditional Chinese medicine: the symptoms are that the patient has little plain menstruation, debilitation, dull pain in lower abdomen, deep and thin pulse, pale tongue with thin and white coating after the medicine flow, and the patient cannot nourish viscera and channels due to the deficiency of plain qi and blood, and the deficiency of qi and blood aggravates the deficiency of qi and blood, namely, pain due to lack of nourishment, qi and blood deficiency, promotes weakness, causes internal stagnation of phlegm and blood stasis, and causes the symptoms due to accumulation. The treatment mainly comprises the steps of benefiting qi and nourishing blood, reducing phlegm and dredging collaterals, and taking the 'urgent treatment of the principal aspect of the disease and the slow treatment of the principal aspect of the disease' into consideration, firstly, the 7-dose of the granule of the example 2 (cassia twig 10g tuckahoe 15g red paeony root 10g tree peony bark 10g peach kernel 10g safflower 10g radices trichosanthis 10g purified pinellia tuber 10g weeping forsythia 10g stiff silkworm 10g rhizoma sparganii 10g zedoary 10g motherwort 10g rhizoma corydalis 10 g) is taken with water in the morning and evening to treat pregnancy residues so as to prevent the mechanization of the pregnancy residues.
The patient has no vaginal bleeding, no abdominal pain, debilitation, normal urination and no obvious discomfort after one week, the abdominal pain of the patient disappears, the traditional Chinese medicine granule of the example 1 (cassia twig 10g tuckahoe 15g red peony root 10g tree peony bark 10g peach kernel 10g safflower 10g radices trichosanthis 10g purified pinellia tuber 10g weeping forsythia 10g stiff silkworm 10g rhizoma sparganii 10g zedoary 10 g) is prepared, namely, the rhizoma corydalis and motherwort are removed, 7 doses are added, and then gynecological B ultrasonic treatment is performed again, and the uterine cavity has no flocculent residues.
TABLE 6 ultrasound diagnostic report before and after treatment
Remarks: pelvic effusion is physiological effusion with a volume of not more than 1 cm.
7 typical case 7-indication of pregnancy residual
Zhang Mou A woman, 27 years old, 2023, 3 months and 4 days old after medical abortion for early pregnancy, 2 weeks after medical abortion, vaginal bleeding still remained, and the symptoms of vaginal bleeding, dysphoria, pharyngeal foreign body sensation, no abdominal pain, insomnia, diminution of urine, deep pulse, pale tongue, plain body, and auxiliary examination: mixed echo clusters are seen in the vaginal color ultrasound uterine cavity, the size of the echo clusters is about 20mmX11mm, the echo clusters are not clearly demarcated with the anterior wall muscle layer, and CDFI: see blood flow signals, which are the spectrum of trophoblast blood flow. The anterior wall muscle layer of uterus has mixed echo mass of about 21mmX11mm, which is not clearly separated from uterine cavity, and the local visible blood vessel pool, the rolling cloud echo appears as boiling sign, CDFI: the low-resistance trophoblast blood flow spectrum and the venous spectrum are presented. Considering that villus tissue is excessively planted and attacks the muscular layer may occur. Western diagnosis: pregnancy residue after drug abortion, diagnosis in traditional Chinese medicine: the symptoms of mass, qi stagnation and blood stasis are that patients like plain food to promote the development of spleen qi, liver qi stagnation and qi stagnation, and qi stagnation and blood stasis after drug flow, and the symptoms are formed. Therefore, the preparation is administered to patients for regulating qi, activating blood circulation, resolving phlegm and resolving masses, and the granule (ramulus Cinnamomi 10g Poria 15g radix Paeoniae Rubra 10g cortex moutan 10g semen Persicae 10g flos Carthami 10g rhizoma Sparganii 10g rhizoma Curcumae 10g radix Trichosanthis 10g fructus forsythiae 10g Bombyx Batryticatus 10g rhizoma Pinelliae Preparata 10 g) 14 of example 1 is administered 1 dose daily, and water is administered after breakfast and supper.
After two weeks, the patient can carry out previous review, has no vaginal bleeding, has no discomfort such as feeling of foreign body in throat, has no abdominal distension and pain, is convenient to adjust, can receive sleep, and can carry out gynecological B ultrasonic review: obvious abnormalities of uterus and appendages are not seen. The gestation residue disappeared after two weeks of administration.
In addition, based on the recipe, stiff silkworm is replaced by centipede, so that the medicine has better curative effect.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the invention.

Claims (10)

1. The traditional Chinese medicine formula for treating pregnancy residue and annexism is characterized by comprising the following raw materials in parts by weight: 8-12 parts of cassia twig, 13-17 parts of poria cocos, 8-12 parts of paeonia lactiflora, 8-12 parts of moutan bark, 8-12 parts of peach kernel, 8-12 parts of safflower, 8-12 parts of radix trichosanthis, 8-12 parts of rhizoma sparganii, 8-12 parts of rhizoma curcumae, 8-12 parts of fructus forsythiae, 8-12 parts of stiff silkworm and 8-12 parts of purified pinellia ternate.
2. The traditional Chinese medicine formula for treating pregnancy residual and accessory cysts according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 10 parts of cassia twig, 15 parts of poria cocos, 10 parts of paeonia lactiflora, 10 parts of cortex moutan, 10 parts of peach kernel, 10 parts of safflower, 10 parts of radix trichosanthis, 10 parts of rhizoma sparganii, 10 parts of rhizoma curcumae, 10 parts of fructus forsythiae, 10 parts of stiff silkworm and 10 parts of rhizoma pinelliae preparata.
3. The traditional Chinese medicine formula for treating pregnancy residual and accessory cyst according to claim 1, wherein the raw materials of the traditional Chinese medicine formula further comprise motherwort herb and rhizoma corydalis; the material is prepared from the following raw materials in parts by weight: 8-12 parts of cassia twig, 13-17 parts of poria cocos, 8-12 parts of paeonia lactiflora, 8-12 parts of moutan bark, 8-12 parts of peach kernel, 8-12 parts of safflower, 8-12 parts of radix trichosanthis, 8-12 parts of rhizoma sparganii, 8-12 parts of rhizoma curcumae, 8-12 parts of fructus forsythiae, 8-12 parts of stiff silkworm, 8-12 parts of rhizoma pinelliae preparata, 8-12 parts of leonurus and 8-12 parts of rhizoma corydalis.
4. The traditional Chinese medicine formula for treating pregnancy residual and accessory cysts according to claim 3, which is characterized by being prepared from the following raw materials in parts by weight: 10 parts of cassia twig, 15 parts of poria cocos, 10 parts of paeonia lactiflora, 10 parts of cortex moutan, 10 parts of peach kernel, 10 parts of safflower, 10 parts of radix trichosanthis, 10 parts of rhizoma sparganii, 10 parts of rhizoma curcumae, 10 parts of fructus forsythiae, 10 parts of stiff silkworm, 10 parts of rhizoma pinelliae preparata, 10 parts of leonurus and 10 parts of rhizoma corydalis.
5. The formula of claim 3, wherein the paeonia is paeonia lactiflora pallas.
6. The traditional Chinese medicine formula for treating pregnancy residual and accessory cysts according to claim 3, wherein the stiff silkworm is replaced by centipede.
7. A Chinese medicinal granule for treating pregnancy residual and accessory cyst, which is prepared according to the Chinese medicinal formulation of any one of claims 1-4.
8. The traditional Chinese medicine granule for treating pregnancy residual and accessory cysts according to claim 7, wherein the traditional Chinese medicine granule is prepared from the following raw materials by weight: 10g of cassia twig, 15g of poria cocos, 10g of peony, 10g of cortex moutan, 10g of peach kernel, 10g of safflower, 10g of radix trichosanthis, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 10g of fructus forsythiae, 10g of stiff silkworm and 10g of rhizoma pinelliae preparata.
9. The traditional Chinese medicine granule for treating pregnancy residual and accessory cysts according to claim 7, wherein the traditional Chinese medicine granule is prepared from the following raw materials by weight: 10g of cassia twig, 15g of poria cocos, 10g of paeonia lactiflora, 10g of cortex moutan, 10g of peach kernel, 10g of safflower, 10g of radix trichosanthis, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 10g of fructus forsythiae, 10g of stiff silkworm, 10g of rhizoma pinelliae preparata, 10g of leonurus and 10g of rhizoma corydalis.
10. Use of a traditional Chinese medicine according to claims 1-6 for the preparation of a medicament for the treatment of pregnancy residual or/and accessory cysts or/and pelvic effusion.
CN202310538458.1A 2023-05-12 2023-05-12 Traditional Chinese medicine formula for treating pregnancy residue and annexism cyst, and granule and application thereof Pending CN116585436A (en)

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