CN116528922A - Method for manufacturing filter device and filter device - Google Patents

Abstract

Provided are a filter device and a method for manufacturing the same, wherein the filter device can prevent hollow fibers from adhering to each other and can improve the filter efficiency. In the method for manufacturing the filter device 1 of the present invention, the spacer member 13 is supported by the elongated plate-like core member 12, the hollow fiber 14 is wound around the outer periphery of the spacer member 13 supported by the core member 12 in the short-length direction from one side to the other side in the long-length direction, the core member 12 is pulled out from the spacer member 13 around which the hollow fiber 14 is wound, the hollow fiber wound body 10B around which the hollow fiber 14 is wound around the outer periphery of the spacer member 13 is manufactured, the hollow fiber wound body 10B is wound around the long-length direction to manufacture the columnar filter material 10, and the filter material 10 is stored in the container.

Description

Method for manufacturing filter device and filter device

Technical Field

The present invention relates to a method for manufacturing a filter device and a filter device.

Background

Conventionally, in the case of manufacturing a filter device using hollow fibers, for example, the hollow fibers are alternately turned over on a pair of rod-shaped supports arranged parallel to each other, so as to be wound in the longitudinal direction, and a web to be a ribbon bundle is further wound up to form a filter module (see patent document 1).

Prior art literature

Patent literature

Patent document 1: japanese patent laid-open No. 47-8595

Disclosure of Invention

Problems to be solved by the invention

However, when the hollow fibers bundled in such a state are detached from the support and placed in the container, the hollow fibers are closely adhered to each other, and the filtration efficiency is deteriorated.

The invention aims to provide a filter device capable of preventing hollow fibers from being closely adhered to each other and improving the filtering efficiency, and a manufacturing method thereof.

Means for solving the problems

In order to solve the above-described problems, the present invention provides a method for manufacturing a filter device, comprising supporting a spacer member with an elongated plate-like core member, winding hollow fibers around the outer periphery of the spacer member supported with the core member in the short-length direction from one side to the other side in the long-length direction, extracting the core member from the spacer member around which the hollow fibers are wound, manufacturing a hollow fiber wound body around which the hollow fibers are wound around the outer periphery of the spacer member, winding the hollow fiber wound body in the long-length direction to manufacture a columnar filter material, and storing the filter material in a container.

The spacer is preferably in the form of a mesh.

The spacer is preferably formed in a mesh shape using fibers, the mesh having a pore diameter of 1.5mm to 2.5mm, and the fibers constituting the mesh having a linear diameter of 0.4mm to 0.6mm.

The present invention also provides a filter device comprising: a cylindrical filter material produced by winding up a hollow fiber wound body in which hollow fibers are wound around the outer periphery of a mesh-like spacer member in the longitudinal direction; and a container that houses the filter material.

ADVANTAGEOUS EFFECTS OF INVENTION

According to the present invention, it is possible to provide a filter device and a method for manufacturing the same, which can prevent adhesion of hollow fibers to each other and improve filtration efficiency.

Drawings

Fig. 1 is a diagram illustrating a configuration of a blood circulation circuit 100.

Fig. 2 is a cross-sectional view of a portion including the cleaning filter device 1 and the tube 101 connected to the cleaning filter device 1.

Fig. 3 is a diagram illustrating a method of manufacturing the filter material 10.

Fig. 4 is an exploded perspective view of the cleaning filter device 1.

Fig. 5 is a partially enlarged view of fig. 2.

Fig. 6 is a perspective view of the 2 nd container 20B as seen from the inner surface side.

Fig. 7 is a diagram showing a state in which the operating member 43 is detached from the 1 st attaching/detaching portion 40A.

Fig. 8 is a diagram illustrating a step of attaching the 2 nd attaching/detaching portion 50A of the 2 nd attaching/detaching member 80 to the 1 st attaching/detaching portion 40A of the cleaning filter device 1.

Fig. 9 is a diagram illustrating a removal step of cleaning the filter device 1.

Fig. 10 is a diagram illustrating a removal procedure of the 2 nd attachment/detachment portion 50A and the 1 st attachment/detachment portion 40A.

Detailed Description

Hereinafter, embodiments of the present invention will be described with reference to the drawings.

In the embodiment, the cleaning and filtering apparatus 1 through which the pre-flushing liquid flows is described as an example of the fluid processing apparatus. The extracorporeal circuit is described by taking the blood circulation circuit 100 as an example.

However, the fluid flowing through the fluid processing device is not limited to the pre-flush liquid, and may be blood, another chemical, or the like. The fluid treatment device may be an artificial lung, a blood filter, a heat exchanger, a blood concentrator, a blood reservoir, a blood pump, or the like. The extracorporeal circulation circuit may be a myocardial protection circuit or the like.

(blood circulation circuit 100)

Fig. 1 is a diagram illustrating a configuration of a blood circulation circuit 100. The blood circulation circuit 100 is used in an artificial heart-lung system, and therefore includes a blood reservoir 3, a blood pump 4, an artificial lung 5, a blood filter device 6, and a cleaning filter device 1 for circuit cleaning. The respective devices are connected by a flexible polyvinyl chloride pipe 101 or the like.

In the following description, the blood circulation circuit 100 is referred to as "normal use" when it is used as an artificial heart-lung system for recovering blood from a patient and feeding the blood. Before "normal use", the operation of circulating the pre-flushing liquid (for example, physiological saline) in the blood circulation circuit 100 to remove foreign substances and bubbles existing in the blood circulation circuit 100 is referred to as "pre-flushing".

(blood tank 3)

The blood reservoir 3 stores blood taken out of the patient during normal use and stores priming solution during priming.

(blood Pump 4)

The blood pump 4 is disposed downstream of the blood reservoir 3, and circulates blood or pre-flush. As the blood pump 4, a known centrifugal pump or roller pump is used. In the embodiment, a centrifugal pump is used to drive a rotor provided inside, and pressure is applied to blood or pre-flush to circulate the blood or pre-flush in the blood circulation circuit 100.

(Artificial lung 5)

The artificial lung 5 is disposed downstream of the blood pump 4. In normal use, the artificial lung 5 adjusts the temperature of blood sent from the blood tank 3 to the patient by the blood pump 4, and performs gas exchange (oxygen addition, carbon dioxide removal, and the like) of the blood. The oxygen supply is performed by, for example, an oxygen cylinder or the like, and oxygen added to blood is supplied.

(blood filtration device 6)

The blood filtration device 6 filters blood and removes air bubbles in the blood during normal use.

(cleaning Filter device 1)

The cleaning filter device 1 is used in the pre-flushing of the blood circulation circuit 100, and is removed after the pre-flushing. Fig. 2 is a cross-sectional view of a portion including the cleaning filter device 1 and the tube 101 connected to the cleaning filter device 1. The cleaning filter device 1 includes a filter material 10 and a container 20 that accommodates the filter material 10.

(Filter Material 10)

Fig. 3 is a diagram illustrating a method of manufacturing the filter material 10. First, as shown in fig. 3 (a), the supported spacer member 10A supported by the core member 12 is formed by overlapping the grid-like spacer members 13 on the elongated plate-like core member 12. The grid-like spacer 13 is made of a polyolefin polymer material. As the spacer 13, a mesh using a fiber made of polypropylene (PP) or polyethylene terephthalate (PET) is particularly preferably used. A member having an opening area (pore diameter) of 1.5mm to 2.5mm and a fiber diameter of 0.4mm to 0.6mm was used.

In the embodiment, the spacer member 13 is supported by the core member 12 by inserting the core member 12 into the inside of the bag-like (cylindrical) spacer member 13. However, the present invention is not limited to this, and the front and rear surfaces of the core member 12 may be covered with the planar spacer members 13. The spacer member 13 may be disposed on only one surface of the core member 12.

Next, as shown in fig. 3 (b), porous hollow fibers 14 are wound around the outer periphery of the supported spacer 10A.

At this time, the hollow fiber 14 is wound so as to extend in the short dimension direction S of the supported spacer 10A. That is, the hollow fiber 14 is wound from one end to the other end in the short dimension direction S on one surface side of the supported spacer 10A, is turned to the other end in the short dimension direction S, is wound from the other end to the one end in the short dimension direction on the other surface side of the supported spacer 10A, and is turned to the one end in the short dimension direction. The above operation is repeated, and the hollow fiber 14 is wound around the outer periphery of the supported spacer 10A. In this case, it is preferable that adjacent hollow fibers 14 are wound without overlapping each other and without any gap.

Then, winding of the hollow fiber 14 is performed from one side to the other side in the longitudinal direction L of the supported spacer 10A, and the hollow fiber 14 is wound over the substantially entire area of the supported spacer 10A.

Next, as shown in fig. 3 (c), the core member 12 is extracted from the side of the supported spacer member 10A around which the hollow fibers 14 are wound in the longitudinal direction L, and the hollow fiber wound body 10B around which the hollow fibers 14 are wound is formed around the outer periphery of the spacer member 13.

Then, as shown in fig. 3 (d), the hollow fiber wound body 10B is wound up from one side to the other side in the longitudinal direction L, and the cylindrical filter material 10 wound in a roll shape is formed.

If the hollow fibers 14 are wound around the spacer 13 without any gap around the filter 10 manufactured in this way, the hollow fibers 14 are uniformly arranged on the surface of the spacer 13. Thus, even when the hollow fibers 14 are wound in a roll shape and formed into a cylindrical shape, the hollow fibers can be uniformly arranged without omission, and thus, no unevenness in filtration occurs.

Since the hollow fibers 14 are wound around the spacer member 13, even when the core member 12 is taken out and wound in a roll shape to be cylindrical, the arrangement state of the hollow fibers 14 can be maintained, and thus, no filtration unevenness occurs.

Further, since the hollow fibers 14 are wound around the spacer 13, the hollow fibers 14 can be prevented from adhering to each other. Further, since the spacer 13 has a mesh shape, pressure loss during filtration can be suppressed. Further, the amount of the hollow fibers 14 corresponding to the spacer members 13 can be reduced.

Fig. 4 is an exploded perspective view of the cleaning filter device 1. Fig. 5 is a partially enlarged view of fig. 2. The container 20 includes a 1 st container 20A disposed on the upstream side (inlet side) of the fluid and a 2 nd container 20B disposed on the downstream side (outlet side) of the fluid.

(1 st container 20A)

The 1 st container 20A includes a 1 st cylindrical portion 23, a 1 st end surface portion 24 in the form of a circular plate covering an inlet side, which is one axial end portion of the 1 st cylindrical portion 23, and a fluid inlet (1 st fluid inlet/outlet) 25 extending axially upstream from a central portion of the 1 st end surface portion 24.

(1 st connecting portion 30A)

The 1 st coupling portion 30A is provided on the other end portion of the 1 st cylindrical portion 23, that is, on the downstream outer surface. The 1 st connecting portion 30A is a portion connected to a 2 nd connecting portion 30B of the 2 nd container 20B described later.

The 1 st connecting portion 30A includes, from the downstream side: in the embodiment, the engagement projections 32 are provided at 8 equal portions in the circumferential direction, and the annular projection 33 is provided on the upstream side of the engagement projections 32 and extends continuously in the circumferential direction. The number of the engaging projections 32 is not limited to 8, and may be 8 or more or 8 or less. The annular protrusion 33 may be intermittent, and may be discontinuous in the circumferential direction.

The protruding amount of the engagement protrusion 32 from the outer surface of the 1 st cylindrical portion 23 increases from the downstream side to the upstream side. That is, the outer surface of the engagement protrusion 32 is formed with a slope 34 that increases from the downstream side to the upstream side.

(2 nd Container 20B)

The 2 nd container 20B includes a cylindrical 2 nd tubular portion 26, a disk-shaped 2 nd end surface portion 27 covering the outlet side which is the other end portion in the axial direction of the 2 nd tubular portion 26, and a fluid outlet (2 nd fluid inlet/outlet) 28 axially extending downstream from the central portion of the 2 nd end surface portion 27.

(2 nd connecting portion 30B)

The 2 nd coupling portion 30B is a portion provided at one end of the 2 nd tubular portion 26 and coupled to the 1 st container 20A.

The 2 nd coupling portion 30B includes engagement holes 37 provided at 8 equal locations in the circumferential direction corresponding to the engagement projections 32 of the 1 st tubular portion 23, and a distal end portion 38 provided upstream of the engagement holes 37. The number of the engagement holes 37 is not limited to 8, as is the case with the engagement protrusions 32.

(protruding portion)

Fig. 6 is a perspective view of the 2 nd container 20B as seen from the inner surface side. A protrusion 60 having a slit 61 formed circumferentially and discontinuously is provided on the outer peripheral side of the inner surface side of the 2 nd end surface portion 27 of the 2 nd container 20B. The slits 61 are provided at 6 equal locations in the circumferential direction. However, the number of the sites is not limited to 6, and may be 6 or more or 6 or less.

(O-ring)

An O-ring 62 (not shown in fig. 6) as shown in fig. 2 and 5 is provided on the outer periphery of the projection 60.

As described above, the filter material 10 in which the hollow fibers 14 are wound around the spacer member 13 is first stored in the 1 st container 20A. Then, the downstream end portion of the filter material 10 was adhered by a urethane adhesive and fixed to the 1 st container 20A. As the fixing method, for example, a centrifugal potting method or the like can be used. Then, the 2 nd container 20B is covered on the downstream side opening of the 1 st container 20A, and the 1 st connecting portion 30A and the 2 nd connecting portion 30B are connected.

At this time, the 1 st connecting portion 30A and the 2 nd connecting portion 30B are connected as follows.

When the 2 nd tube portion 26 is inserted into the outer periphery of the 1 st tube portion 23, the diameter of the tip portion 38 of the 2 nd tube portion 26 is enlarged along the inclined surface 34 of the engagement protrusion 32. Then, when the tip end portion 38 of the 2 nd barrel portion 26 exceeds the inclined surface 34 of the engagement protrusion 32, the tip end portion 38 of the 2 nd barrel portion 26 is fitted into the recess between the annular protrusion 33 and the engagement protrusion 32. Thus, the 1 st connecting portion 30A and the 2 nd connecting portion 30B are connected, and the filter material 10 is accommodated in the internal space of the container 20.

At this time, as shown in fig. 2 and 5, when the 1 st container 20A and the 2 nd container 20B are coupled, the O-ring 62 is pressed by the end surface 23a of the 1 st tube portion 23 and the inner surface 27a of the 2 nd side end portion, and is closely adhered to the end surface 23a and the inner surface 27a. This can maintain the air tightness (liquid tightness) between the inner space and the outer space formed by the 1 st container 20A and the 2 nd container 20B.

(device side 1 st attachment/detachment section 40A)

As shown in fig. 2 and 4, the device-side 1 st detachable portion 40A is formed in a cylindrical fluid inlet 25 which extends from the center portion of the 1 st end surface portion 24 in the 1 st container 20A to the upstream side, that is, to the side, and has a smaller diameter than the 1 st tubular portion 23. The device-side 1 st attachment/detachment portion 40A includes a slot portion 41 provided at the front end of the fluid inlet 25, an operation protrusion 42 protruding radially outward from the slot portion 41 toward the 1 st end surface portion 24 on the outer surface of the fluid inlet 25, and an operation member 43 inserted into the slot portion 41 and movable in a radial direction orthogonal to the axial direction P of the device-side 1 st attachment/detachment portion 40A.

Fig. 7 is a diagram showing a state in which the operating member 43 is detached from the device-side 1 st attaching/detaching portion 40A. The operation member 43 includes an insertion portion 44 inserted into the slot portion 41, a pressing portion 45 extending from a part of an outer periphery of the insertion portion 44 in a direction orthogonal to the insertion portion 44 (the axial direction P of the 1 st tubular portion 23), and a biasing portion 46, and the biasing portion 46 extends substantially parallel to the insertion portion 44 from a position on the inner diameter side of the pressing portion 45 of the insertion portion 44 to a position on the inner diameter side of the insertion portion 44.

The insertion portion 44 has a substantially elliptical through hole 47 formed therein. The short diameter r1 of the through hole 47 is substantially equal to the inner diameter r2 of the fluid inlet 25.

When the operating member 43 is inserted into the slot portion 41, the urging portion 46 abuts against the operating protrusion 42. At this time, the surface in the longitudinal direction on the opposite side to the side where the urging portion 46 is provided, of the inner surface of the through hole 47 provided in the insertion portion 44, becomes a locking surface 49 for locking the 2 nd attachment/detachment member 80 described later.

(device side 2. Sup. Nd attaching/detaching portion 50B)

As shown in fig. 4, a device-side 2 nd attaching/detaching portion 50B is formed in a cylindrical fluid outlet 28 that extends from the center portion of the 2 nd end surface portion 27 of the 2 nd container 20B to the other side, i.e., the downstream side, and has a smaller diameter than the 2 nd cylindrical portion 26. The device-side 2 nd attachment/detachment portion 50B includes a 1 st circumferential groove 51 provided on the outer periphery of the base end side of the fluid outlet 28, and a 2 nd circumferential groove 52 provided on the outer periphery of the tip end side of the fluid outlet 28. An O-ring 53 is mounted on the 2 nd circumferential groove 52.

(No. 2 attachment and detachment part 80)

As shown in fig. 2, an upstream pipe 101U is connected to the device-side 1 st attachment/detachment portion 40A on the inlet side of the cleaning filter device 1. The 2 nd attaching/detaching member 80 is attached to the upstream side pipe 101U, and a pipe side 2 nd attaching/detaching portion 50A having the same structure as the apparatus side 2 nd attaching/detaching portion 50B on the outlet side of the cleaning filter apparatus 1 is formed.

The 2 nd attaching/detaching member 80 includes an insertion portion 81 inserted into the upstream pipe 101U, an abutting portion 82 abutting against the tip end of the upstream pipe 101U, and a pipe-side 2 nd attaching/detaching portion 50A extending from the abutting portion 82 to the outside of the upstream pipe 101U.

The pipe-side 2 nd attaching/detaching portion 50A includes a 1 st circumferential groove 51 having an outer diameter on an inner diameter side that can be inserted into the apparatus-side 1 st attaching/detaching portion 40A and provided on an outer periphery on an upstream side, and a 2 nd circumferential groove 52 provided on an outer periphery on a downstream side. An O-ring 53 is mounted on the 2 nd circumferential groove 52. In the pipe-side 2 nd attaching/detaching portion 50A, the same reference numerals are used for the same portions as those of the apparatus-side 2 nd attaching/detaching portion 50B.

The lock mechanism for locking and unlocking the device side 2 nd attachment/detachment portion 50B or the tube side 2 nd attachment/detachment portion 50A with respect to the tube side 1 st attachment/detachment portion 40B or the device side 1 st attachment/detachment portion 40A is constituted by a lock surface 49 provided on the operation member 43, a pressing portion 45 provided on the operation member 43, and a 1 st circumferential groove 51 of the device side 2 nd attachment/detachment portion 50B or the tube side 2 nd attachment/detachment portion 50A described later.

That is, in the present embodiment, the lock mechanism can lock and unlock the pipe 1 st attachment/detachment portion 40B and the pipe 2 nd attachment/detachment portion 50A or the apparatus 2 nd attachment/detachment portion 50B, and can lock and unlock the apparatus 1 st attachment/detachment portion 40A and the pipe 2 nd attachment/detachment portion 50A.

(mounting action)

The pipe-side 2 nd attaching/detaching portion 50A of the 2 nd attaching/detaching member 80 provided to the upstream pipe 101U and the device-side 1 st attaching/detaching portion 40A provided to the fluid inlet 25 of the cleaning and filtering device 1 are attached as follows.

Fig. 8 is a diagram illustrating a procedure of attaching the pipe-side 2 nd attaching/detaching portion 50A of the 2 nd attaching/detaching member 80 provided in the upstream side pipe 101U to the apparatus-side 1 st attaching/detaching portion 40A of the cleaning and filtering apparatus 1.

As shown in fig. 8 (a), in a state in which the pipe-side 2 nd attaching/detaching portion 50A of the 2 nd attaching/detaching member 80 is not inserted into the device-side 1 st attaching/detaching portion 40A of the cleaning filter device 1, the urging portion 46 abuts against the operation protrusion 42. At this time, the position of the locking surface 49 provided in the through hole 47 of the insertion portion 44 is a position P1 shown in the drawing.

As shown in fig. 8 (b), when the pipe-side 2 nd attaching/detaching portion 50A of the 2 nd attaching/detaching member 80 is inserted into the apparatus-side 1 st attaching/detaching portion 40A of the cleaning filter apparatus 1, the tip portion of the pipe-side 2 nd attaching/detaching portion 50A abuts against the locking surface 49, and the locking surface 49 is pressed downward from the position P1 shown in the drawing.

As a result, as shown in fig. 8 (c), the tip of the biasing portion 46 abuts against the operation protrusion 42, and therefore cannot move downward, but the base end of the biasing portion 46 moves downward as shown by the arrow in the figure, and the biasing portion 46 flexes. Then, the position of the locking surface 49 is moved from the illustrated position P1 to the position P2. Thereby, the pipe-side 2 nd attaching/detaching portion 50A of the 2 nd attaching/detaching member 80 can be inserted into the inside of the apparatus-side 1 st attaching/detaching portion 40A of the cleaning filter apparatus 1.

As shown in fig. 8 (d), the pipe-side 2 nd attaching/detaching portion 50A of the 2 nd attaching/detaching member 80 is inserted into the front end of the device-side 1 st attaching/detaching portion 40A of the cleaning filter device 1, and when the 1 st circumferential groove 51 of the pipe-side 2 nd attaching/detaching portion 50A reaches the position of the insertion portion 44, the lock surface 49 is moved from the position P2 to the position P1 in the drawing by the restoring force of the urging portion 46.

Accordingly, the lock surface 49 is fitted into the 1 st circumferential groove 51, and thus the cleaning filter device 1 is connected to the upstream pipe 101U in a locked state in which the device-side 1 st attachment/detachment portion 40A and the pipe-side 2 nd attachment/detachment portion 50A are prevented from coming off.

As described above, the installation of the 2 nd attachment/detachment member 80 of the upstream side pipe 101U and the device side 1 st attachment/detachment portion 40A of the cleaning filter device 1 can be performed by a one-touch operation of inserting only the 2 nd attachment/detachment member 80 of the upstream side pipe 101U into the device side 1 st attachment/detachment portion 40A of the cleaning filter device 1. Therefore, the upstream side pipe 101U is easily connected to the cleaning filter device 1.

(1 st attachment/detachment member 90)

As shown in fig. 2, a downstream pipe 101D is connected to the device-side 2 nd attachment/detachment portion 50B on the outlet side of the cleaning filter device 1. A 1 st attachment/detachment member 90 having a tube-side 1 st attachment/detachment portion 40B having the same structure as the apparatus-side 1 st attachment/detachment portion 40A on the inlet side of the cleaning filter apparatus 1 is attached to the downstream side tube 101D.

As shown in fig. 2 and 4, the 1 st detachable member 90 includes an insertion portion 91 that is inserted into the downstream pipe 101D, and a pipe-side 1 st detachable portion 40B that extends outward from the distal end of the downstream pipe 101D.

The pipe-side 1 st detachable portion 40B has an inner diameter that can be inserted into the outer diameter side of the device-side 2 nd detachable portion 50B, and includes a slot portion 41, an operation protrusion 42, and an operation member 43, similarly to the device-side 1 st detachable portion 40A. In the pipe-side 1 st attaching/detaching portion 40B, the same reference numerals are used for the same portions as those of the apparatus-side 1 st attaching/detaching portion 40A.

(mounting action)

The installation of the 1 st detachable portion 40B on the pipe side of the 1 st detachable member 90 provided on the downstream side pipe 101D and the 2 nd detachable portion 50B on the device side provided on the fluid outlet 28 of the cleaning and filtering device 1 is the same as the installation of the 2 nd detachable portion 50A on the pipe side of the 2 nd detachable member 80 provided on the upstream side pipe 101U and the 1 st detachable portion 40A on the device side provided on the fluid inlet 25 of the cleaning and filtering device 1 on the upstream side, and therefore, the description thereof is omitted.

The installation of the pipe-side 1 st attaching/detaching portion 40B of the downstream pipe 101D and the apparatus-side 2 nd attaching/detaching portion 50B of the cleaning filter apparatus 1 can also be performed by a one-touch operation of inserting only the pipe-side 1 st attaching/detaching portion 40B of the downstream pipe 101D into the apparatus-side 2 nd attaching/detaching portion 50B of the cleaning filter apparatus 1. Therefore, the downstream side pipe 101D is easily connected to the cleaning filter device 1.

(Pre-punching)

Returning to fig. 1, at the time of priming, the blood circulation circuit 100 is constructed so as not to pass through the circulation circuit in the patient.

First, the tube 102 having the vial needle 103 attached to the tip thereof is connected to the blood reservoir 3, and the vial needle 103 is connected to a container for pre-flushing, not shown, such as physiological saline. When the blood pump 4 is driven, a pre-flush fluid such as physiological saline flows into the blood reservoir 3. The fluid flowing into the blood reservoir 3 is sucked by the blood pump 4 and passes through the channel L1, and is separated into a channel L2 and a channel L3 in 2 directions by the artificial lung 5. The fluid passing through the one side channel L2 enters the blood filter device 6. The fluid passing through the other flow path L3 is further separated into 2-directional flow paths L4 and L5. The fluid in the channel L4 enters the hemofilter device 6, merges with the fluid in the channel L2, flows through the channel L6, and returns to the blood reservoir 3. The fluid in the flow path L5 is further separated into 2-directional flow paths L7 and L8. The fluid in the flow path L7 flows through the cleaning filter device 1.

Here, in the cleaning filter device 1, foreign substances in the blood circulation circuit 100 flowing together with the fluid are removed. The foreign matter-removed fluid is separated into the flow path L9 and the flow path L10, then merges with the flow path L7, and flows through the flow path L5, and then flows into the blood reservoir 3. The air present in the blood circulation circuit 100 also flows together with the fluid into the blood reservoir 3.

As shown in fig. 5, when the 1 st container 20A and the 2 nd container 20B are coupled, the O-ring 62 is pressed by the end surface 23a of the 1 st tube portion 23 and the inner surface 27a of the 2 nd side end portion, and the air tightness (liquid tightness) between the inner space and the outer space formed by the 1 st container 20A and the 2 nd container 20B can be maintained.

In this state, when the pre-flush fluid flows, the fluid flows as indicated by an arrow in the figure. At this time, there is a possibility that bubbles 70 remain in a minute gap generated between the O-ring 62 and the protrusion 60.

However, in the embodiment, as shown in fig. 6, a slit 61 is formed in the protruding portion 60. Accordingly, as shown by the arrows in fig. 6, a part of the fluid flowing on the inner surface side of the 2 nd container 20B can flow through the slit 61 in the gap generated between the O-ring 62 and the protrusion 60. Therefore, the air bubbles 70 between the O-ring 62 and the protrusion 60 can also flow out together with the fluid and flow out to the blood reservoir 3.

Then, the driving of the blood pump 4 is stopped after the end of the priming.

(removal of cleaning Filter device 1)

Fig. 9 is a diagram illustrating a removal step of cleaning the filter device 1. After the end of the pre-flushing, as shown in fig. 9 (a), first, the cleaning filter device 1 is clamped up and down. Then, the pipe-side 2 nd attaching/detaching portion 50A of the upstream-side pipe 101U on the upstream side is detached from the apparatus-side 1 st attaching/detaching portion 40A of the cleaning filter apparatus 1.

Fig. 10 is a diagram illustrating a procedure of removing the pipe-side 2 nd attaching/detaching portion 50A and the device-side 1 st attaching/detaching portion 40A.

First, when the pressing portion 45 is pressed in the direction of the arrow shown in fig. 10 (a), the insertion portion 44 moves downward in the drawing. Thus, the locking surface 49 provided in the through hole 47 of the insertion portion 44 is separated from the bottom surface of the 1 st circumferential groove 51, and the device-side 1 st attachment/detachment portion 40A and the tube-side 2 nd attachment/detachment portion 50A are unlocked. As a result, as shown in fig. 10 (b), the pipe-side 2 nd attaching/detaching portion 50A can be pulled out from the apparatus-side 1 st attaching/detaching portion 40A.

As described above, the removal of the pipe-side 2 nd attaching/detaching portion 50A of the 2 nd attaching/detaching member 80 of the upstream side pipe 101U from the apparatus-side 1 st attaching/detaching portion 40A of the cleaning and filtering apparatus 1 can also be performed by a one-touch operation of pulling out the 2 nd attaching/detaching member 80 of the upstream side pipe 101U from the apparatus-side 1 st attaching/detaching portion 40A of the cleaning and filtering apparatus 1 by pressing only the pressing portion 45. Therefore, the upstream side pipe 101U is easily removed from the cleaning filter device 1.

The removal of the pipe-side 1 st removing portion 40B of the downstream pipe 101D and the device-side 2 nd removing portion 50B of the cleaning and filtering device 1 can be performed by a one-touch operation of removing the pipe-side 1 st removing portion 40B of the downstream pipe 101D from the device-side 2 nd removing portion 50B of the cleaning and filtering device 1 by pressing only the pressing portion 45, similarly to the removal of the 2 nd removing member 80 of the upstream pipe 101U from the device-side 1 st removing portion 40A of the cleaning and filtering device 1. Therefore, the downstream side pipe 101D is easily removed from the cleaning filter device 1.

Then, as shown in fig. 9 (B), the cleaning and filtration device 1 removed from the tube-side 2 nd attachment/detachment portion 50A of the 2 nd attachment/detachment member 80 inserted into the upstream tube 101U and the tube-side 1 st attachment/detachment portion 40B of the 1 st attachment/detachment member 90 inserted into the downstream tube 101D is removed by the blood circulation circuit 100.

Next, as shown in fig. 9 (c), the pipe-side 2 nd attaching/detaching portion 50A of the 2 nd attaching/detaching member 80 of the upstream pipe 101U and the pipe-side 1 st attaching/detaching portion 40B of the downstream pipe 101D are connected. At this time, as described above, the pipe-side 2 nd attaching/detaching portion 50A and the pipe-side 1 st attaching/detaching portion 40B can be connected by one touch. Therefore, the upstream pipe 101U and the downstream pipe 101D are easily connected.

After the tubes are connected to each other, the flow paths L9 and L10 shown in fig. 1 are each cut off in the middle, and the catheter is connected to the cut-off portion, whereby the blood circulation circuit 100 becomes an artificial heart-lung system that removes foreign substances and has no air bubbles remaining.

In addition, in the case where the fluid treatment device is an artificial lung, when the fluid treatment device is used, clogging of the fluid treatment device may occur. In this case, replacement of the clogged fluid treatment device or replacement of the entire blood line including the fluid treatment device other than the artificial lung may be considered.

In this case, too, the fluid treatment device and the other fluid treatment device can be easily removed from between the upstream side pipe 101U and the downstream side pipe 101D, and there is an effect of reducing the cost when the extracorporeal circulation system including the pipe is replaced as a whole.

While the preferred embodiments of the present invention have been described above, the present invention is not limited to the above embodiments and can be implemented in various ways.

For example, the structure of the lock mechanism is not limited to the lock surface 49 and the operating member 43 as in the embodiment, and may be other structures as long as the lock mechanism can be attached and detached in one touch.

In the embodiment, the device-side 1 st attachment/detachment portion 40A and the tube-side 1 st attachment/detachment portion 40B are provided at the end portions of the fluid inlet 25 and the downstream side tube 101D of the cleaning and filtration device 1, and the tube-side 2 nd attachment/detachment portion 50A and the device-side 2 nd attachment/detachment portion 50B are provided at the end portions of the upstream side tube 101U and the fluid outlet 28 of the cleaning and filtration device 1.

However, the present invention is not limited thereto, and the pipe-side 2 nd attaching/detaching portion 50A and the device-side 2 nd attaching/detaching portion 50B may be provided at the end of the downstream pipe 101D and the fluid inlet 25 of the cleaning and filtering device 1, and the device-side 1 st attaching/detaching portion 40A and the pipe-side 1 st attaching/detaching portion 40B may be provided at the end of the fluid outlet 28 of the cleaning and filtering device 1 and the upstream pipe 101U.

Description of the reference numerals

1 cleaning filter equipment (fluid treatment equipment)

5 Artificial lung

10 Filter Material

10A supported spacer

10B hollow fiber winding body

11 urethane resin

12 core component

13 spacer member

14 hollow fiber

20 container

20A 1 st Container

20B 2 nd Container

23 1 st barrel portion

23a end face

24 st end face portion 1

25 fluid inlet (fluid inlet and outlet 1)

26 2 nd barrel portion

27 nd end face portion

27a inner surface

28 fluid outlet (fluid inlet and outlet 2)

30A 1 st connecting portion

30B No. 2 connecting portion

32 engagement projection

33 annular projection

34 inclined plane

37 clamping hole

38 front end portion

40A device side 1 st attachment/detachment section

40B tube side 1 st mounting/dismounting portion

41 slot portions

42 operating tab

43 operating parts (locking mechanism)

44 insert (locking mechanism)

45 pressing part

46 force application part

47 through hole

49 locking surface (locking mechanism)

50A tube side 2 nd mounting/dismounting portion

50B device side 2 nd attachment/detachment section

51 1 st circumferential groove (locking mechanism)

60 protruding part

61 slit

62O-ring

70 bubble

80 No. 2 mounting and dismounting parts

81 insertion portion

82 contact portion

90 st loading and unloading component

91 insert part

100 blood circulation circuit (extracorporeal circulation circuit)

101U upstream side pipe (2 nd pipe)

101D downstream side pipe (1 st pipe)

Claims (4)

1. A method for manufacturing a filter device, wherein,

the spacer member is supported by means of an elongated plate-like core member,

winding hollow fibers around the outer circumference of the spacer member supported by the core member in the short-dimension direction from one side to the other side in the long-dimension direction,

withdrawing the core member from the spacer member around which the hollow fibers are wound, producing a hollow fiber wound body around which the hollow fibers are wound around the outer periphery of the spacer member,

the hollow fiber wound body is rolled up in the longitudinal direction to manufacture a cylindrical filter material,

the filter material is stored in a container.

2. The method of manufacturing a filter device according to claim 1, wherein the spacer member is in a mesh shape.

3. The method for manufacturing a filter device according to claim 1, wherein the spacer member is formed in a mesh shape using fibers, the mesh has a pore diameter of 1.5mm to 2.5mm, and the fibers constituting the mesh have a wire diameter of 0.4mm to 0.6mm.

4. A filter device is provided with:

a cylindrical filter material produced by winding up a hollow fiber wound body in which hollow fibers are wound around the outer periphery of a mesh-like spacer member in the longitudinal direction; and

a container which accommodates the filter material.