CN116492398A - 一种治疗风湿关节炎的外涂药液及其制备方法和应用 - Google Patents
一种治疗风湿关节炎的外涂药液及其制备方法和应用 Download PDFInfo
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Abstract
本发明属于中药技术领域,涉及一种治疗风湿关节炎的外涂药液及其制备方法和应用,其包括以下步骤:1)、将野生山七、枇杷皮、皂角、钩藤、九龙腾、半枫荷和火炭母清洗晾干后按任意比例分成两份;2)、选其中一份放入高度米酒中进行浸泡,浸泡时间不低于45日,浸泡结束后过滤,留取浸泡药液一;3)、将另一份放入浸泡药液一中进行浸泡,浸泡时间不低于45日,浸泡结束后过滤,留取浸泡药液二;4)、将虎头蜂与高度白酒放置于玻璃酒瓶中清洗浸泡,浸泡时间不低于60日,待浸泡结束后过滤,留取浸泡药液三;5)、将浸泡药液二与浸泡药液三进行搅拌混合;6)、搅拌混合后的药液进行装瓶。其可以用于风湿关节炎的治疗,且疗效好,无副作用。
Description
技术领域
本发明属于中药技术领域,涉及一种外涂药液及其制备方法和应用,尤其是一种治疗风湿关节炎的外涂药液及其制备方法和应用。
背景技术
风湿关节炎被认为是一种自身免疫性疾病。发病时,免疫系统侵袭关节内和起缓冲作用的组织,以及身体许多其他部位的结缔组织,如血管、肺。久而久之,软骨、骨和关节韧带被侵蚀(磨损),导致关节畸形、不稳定和形成关节内瘢痕,而且患此病后关节的毁损速度不一。
风湿关节炎可突然发生,全身多关节同时发病。但更常见的是缓慢发病,逐渐累及不同的关节。关节炎症常是对称性的,也就是说身体一侧的某个关节发病时,身体另一侧的相同关节也发病。风湿关节炎可累及任何关节,但最先发炎的通常是以下部位的小关节。发炎的关节通常会出现疼痛和僵硬感,尤其是在刚醒后(这种僵硬通常会持续60分钟以上)或长时间不活动后。有些人会感到疲倦和无力,特别是午后不久。同时,风湿关节炎还可以引起食欲下降,伴体重减轻和低热。
目前临床上防治风湿关节炎采用的西药,如非甾体类抗炎药和糖皮质激素虽然对控制症状疗效较好,但无法抑制病情进展及关节结构的破坏,同时掩盖了病情进展的临床表现;即使联用改善病情的抗风湿药,仍有相当比例的患者无法达到预期治疗目的。
近年来,生物治疗及干细胞移植为风湿关节炎治疗开辟了新途径,但由于价格昂贵、不能口服、不能选择性到达靶组织等局限,这些方法仅适合少数特定患者。同时,西药长期治疗会产生消化道溃疡、骨髓抑制、皮疹、肝肾损害、白细胞减低等多种不良反应,甚至造成药源性疾病,导致治疗效果欠佳或治疗失败。
而且,目前现有的治疗风湿关节炎的中药存在配方传统,对于疾病的症状可缓解而无法治愈,导致风湿关节炎的治愈率较低的问题。
因此,鉴于现有技术的缺陷,迫切需要研制一种新型的治疗风湿关节炎的药物。
发明内容
本发明的目的在于克服现有技术中存在的缺点,提供一种治疗风湿关节炎的外涂药液及其制备方法和应用,其可以用于风湿关节炎的治疗,且疗效好,无副作用。
为了实现上述目的,本发明提供如下技术方案:
一种治疗风湿关节炎的外涂药液的制备方法,其特征在于,包括以下步骤:
1)、将野生山七、枇杷皮、皂角、钩藤、九龙腾、半枫荷和火炭母清洗晾干后按任意比例分成两份,且每份中不超过四种药材;
2)、任选其中一份放入高度米酒中进行浸泡,浸泡时间不低于45日,待浸泡结束后,过滤掉药渣,留取浸泡药液一备用;
3)、将另一份放入所述浸泡药液一中继续进行浸泡,浸泡时间不低于45日,待浸泡结束后,过滤掉药渣,留取浸泡药液二备用;
4)、将虎头蜂与高度白酒放置于玻璃酒瓶中进行清洗浸泡,浸泡时间不低于60日,待浸泡结束后,过滤掉蜂渣,留取浸泡药液三备用;
5)、将所述浸泡药液二与浸泡药液三按照一定比例进行搅拌混合;
6)、搅拌混合后的药液进行装瓶。
优选地,所述步骤1)中,各种药材的用量为:野生山七10kg、枇杷皮2.5kg、皂角2.5kg、钩藤5kg、九龙腾5kg、半枫荷2.5kg、火炭母2kg。
优选地,所述步骤2)中,高度米酒的用量为45kg。
优选地,所述步骤4)中,虎头蜂的用量为0.5kg,高度米酒的用量为5kg。
优选地,所述步骤2)和4)中,使用的高度米酒的度数为52-53度。
优选地,所述步骤5)中,所述浸泡药液二与浸泡药液三的比例为6:1。
优选地,所述步骤6)中,每瓶中装入的搅拌混合后的药液为30g。
此外,本发明还提供一种治疗风湿关节炎的外涂药液,其特征在于,其采用上诉制备方法制备而成。
而且,本发明还提供上述治疗风湿关节炎的外涂药液用于治疗风湿关节炎的应用。
优选地,将搅拌混合后的药液均匀涂抹至患处,每天早晚各涂抹患处一次,每次涂抹患处药液不超过0.5g,涂抹周期为7-15天。
与现有技术相比,本发明的铝合金喷射成形圆锭的致密化制备方法具有如下有益技术效果:
1、本发明采用多种中药按照特定比例浸泡而成,经过验证,其对风湿关节炎的治疗效果好。
2、本发明采用中药制成且为外涂药液,因此,其不具有副作用,对患者无不利影响。
3、本发明的外涂药液在制备时只需要进行浸泡工艺,无需采用复杂的制备工艺和制备设备,制作方法简单,成本低,便于推广应用。
附图说明
图1是本发明的治疗风湿关节炎的外涂药液的制备方法的流程图。
具体实施方式
为解决现有风湿关节炎治疗过程中存在的问题,发明人经过长期的研究,发明了一种治疗风湿关节炎的外涂药液及其制备方法和应用,其可以用于风湿关节炎的治疗,且疗效好,无副作用。
为使本发明实施例的目的、技术方案和优点更加清楚,下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例是本发明一部分实施例,而不是全部的实施例。通常在此处附图中描述和示出的本发明实施例的组件可以以各种不同的配置来布置和设计。
因此,以下对在附图中提供的本发明的实施例的详细描述并非旨在限制要求保护的本发明的范围,而是仅仅表示本发明的选定实施例。基于本发明中的实施例,本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
图1示出了本发明的治疗风湿关节炎的外涂药液的制备方法的流程图。如图1所示,本发明的治疗风湿关节炎的外涂药液的制备方法,包括以下步骤:
一、将野生山七、枇杷皮、皂角、钩藤、九龙腾、半枫荷和火炭母清洗晾干后按任意比例分成两份,且每份中不超过四种药材。
其中,野生山七味微苦、甘、性温,具有消肿定痛的作用,对于风湿痛、跌扑肿痛有一定的效果。
枇杷皮不但含有丰富的维生素C,而且,具有治疗风湿筋骨痛的作用。
皂角具有消肿散结的作用,可以疏散风湿关节炎的肿胀等。
钩藤根性寒、味苦涩,具有舒经活络、清热消肿等功效,可用于治疗各种原因引起的关节疼痛半身不遂、肢体水肿、跌扑损伤、以及痛风。
九龙藤入药后味甘略苦,性质温和,可以排出人体内风湿毒气,可缓解风湿所引起关节疼痛,起到祛风祛湿效果,可用于治疗风湿痹痛。
半枫荷性温、味甘,具有祛风除湿,舒筋活血,可用于风湿性关节炎,类风湿关节炎,腰肌劳损,慢性腰腿痛,半身不遂,跌打损伤,扭挫伤的治疗。
火炭母(又称白饭草、老虎尿)益气行血、祛风解热,可治疗气滞血瘀导致的疼痛、风热头痛等。
在本发明中,通过选择野生山七、枇杷皮、皂角、钩藤、九龙腾、半枫荷和火炭母作为药材,使得制备的外涂药液具有较好的治疗效果。
优选地,各种药材的用量为:野生山七10kg、枇杷皮2.5kg、皂角2.5kg、钩藤5kg、九龙腾5kg、半枫荷2.5kg、火炭母2kg。经过大量的研究和试用证明,上述配比制备的外涂药液的治疗效果最好。
并且,将上述七种药材分成两份,四种药材成为一份,另外三种药材成为另一份。至于将哪四种药材成为一份,哪三种药材成为另一份,则不作限定。
二、任选其中一份放入高度米酒中进行浸泡,浸泡时间不低于45日,待浸泡结束后,过滤掉药渣,留取浸泡药液一备用。
在本发明中,任选其中一份药材放入高度米酒中进行浸泡。其中,根据药材的用量,使得高度米酒的用量为45kg。由此,使得高度米酒能够将药材中的有效成分充分地浸泡出来。
并且,优选地,使用的高度米酒的度数为52-53度。这种度数的高度米酒,可以将药材中的有效成分更好地浸泡出来。
三、将另一份放入所述浸泡药液一中继续进行浸泡,浸泡时间不低于45日,待浸泡结束后,过滤掉药渣,留取浸泡药液二备用。
优选地,在步骤二和三中,在进行浸泡时,最好进行密封浸泡,且浸泡时放置在阴凉处,防止太阳直晒。
四、将虎头蜂与高度白酒放置于玻璃酒瓶中进行清洗浸泡,浸泡时间不低于60日,待浸泡结束后,过滤掉蜂渣,留取浸泡药液三备用。
其中,虎头蜂(又称地王蜂)的蜂毒中含有蚁酸、蛋白质、多肽类、酶类、生物胺等成分,其对风湿病、关节炎、风湿性关节炎有很好的治疗作用。本发明中将虎头蜂泡入高度米酒中时,使得虎头蜂的尾针会释放毒液进入所述高度米酒中,这种毒液被高度米酒中的酒精稀释后会产生化学变化,对关节炎、风湿具有非常好的疗效。
优选地,虎头蜂的用量为0.5kg,高度米酒的用量为5kg。这种配比,即能够保证虎头蜂的毒液不会对身体造成损坏,而且使得制备的药液具有良好的治疗效果。
更优选地,使用的高度米酒的度数也为52-53度。这种度数的高度米酒,可以将虎头蜂的毒液完全浸泡出来并且能够与毒液进行化学变化,形成有益的治疗成分。
同时,在进行浸泡时,优选地,将玻璃酒瓶口密封好后置于阴凉处进行浸泡,避免太阳直晒。
五、将所述浸泡药液二与浸泡药液三按照一定比例进行搅拌混合。
浸泡结束后,将所述浸泡药液二与浸泡药液三按照一定比例进行搅拌混合,即可制得本发明的外涂药液。
其中,所述浸泡药液二与浸泡药液三的比例为6:1。经过大量的研究和实验验证发现,这种比例的治疗效果最好。
六、搅拌混合后的药液进行装瓶。
为了便于销售和使用,将搅拌混合后的药液进行装瓶。
优选地,每瓶中装入的搅拌混合后的药液为30g。每瓶中这种量的药液既能够保证患者一个周期的治疗使用,也避免装入过多、使用时间过程而使得药效降低,造成浪费。
在使用本发明的治疗风湿关节炎的外涂药液治疗风湿关节炎时,可以打开药瓶,将搅拌混合后的药液均匀涂抹至患处。其中,每天早晚各涂抹患处一次,每次涂抹患处药液不超过0.5g,涂抹周期为7-15天。经过一个周期的使用,风湿关节炎的症状会得到显著减轻。
本发明的上述实施例仅仅是为清楚地说明本发明所作的举例,而并非是对本发明的实施方式的限定。对于所属领域的普通技术人员来说,在上述说明的基础上还可以做出其它不同形式的变化或变动。这里无法对所有的实施方式予以穷举。凡是属于本发明的技术方案所引伸出的显而易见的变化或变动仍处于本发明的保护范围之列。
Claims (10)
1.一种治疗风湿关节炎的外涂药液的制备方法,其特征在于,包括以下步骤:
1)、将野生山七、枇杷皮、皂角、钩藤、九龙腾、半枫荷和火炭母清洗晾干后按任意比例分成两份,且每份中不超过四种药材;
2)、任选其中一份放入高度米酒中进行浸泡,浸泡时间不低于45日,待浸泡结束后,过滤掉药渣,留取浸泡药液一备用;
3)、将另一份放入所述浸泡药液一中继续进行浸泡,浸泡时间不低于45日,待浸泡结束后,过滤掉药渣,留取浸泡药液二备用;
4)、将虎头蜂与高度白酒放置于玻璃酒瓶中进行清洗浸泡,浸泡时间不低于60日,待浸泡结束后,过滤掉蜂渣,留取浸泡药液三备用;
5)、将所述浸泡药液二与浸泡药液三按照一定比例进行搅拌混合;
6)、搅拌混合后的药液进行装瓶。
2.根据权利要求1所述的治疗风湿关节炎的外涂药液的制备方法,其特征在于,所述步骤1)中,各种药材的用量为:野生山七10kg、枇杷皮2.5kg、皂角2.5kg、钩藤5kg、九龙腾5kg、半枫荷2.5kg、火炭母2kg。
3.根据权利要求2所述的治疗风湿关节炎的外涂药液的制备方法,其特征在于,所述步骤2)中,高度米酒的用量为45kg。
4.根据权利要求3所述的治疗风湿关节炎的外涂药液的制备方法,其特征在于,所述步骤4)中,虎头蜂的用量为0.5kg,高度米酒的用量为5kg。
5.根据权利要求4所述的治疗风湿关节炎的外涂药液的制备方法,其特征在于,所述步骤2)和4)中,使用的高度米酒的度数为52-53度。
6.根据权利要求5所述的治疗风湿关节炎的外涂药液的制备方法,其特征在于,所述步骤5)中,所述浸泡药液二与浸泡药液三的比例为6:1。
7.根据权利要求6所述的治疗风湿关节炎的外涂药液的制备方法,其特征在于,所述步骤6)中,每瓶中装入的搅拌混合后的药液为30g。
8.一种治疗风湿关节炎的外涂药液,其特征在于,其采用权利要求1-7中任一项所述的制备方法制备而成。
9.权利要求8所述的治疗风湿关节炎的外涂药液用于治疗风湿关节炎的应用。
10.根据权利要求9所述的应用,其特征在于,将搅拌混合后的药液均匀涂抹至患处,每天早晚各涂抹患处一次,每次涂抹患处药液不超过0.5g,涂抹周期为7-15天。
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