CN116491911B - Heart failure monitoring equipment testing system and method - Google Patents
Heart failure monitoring equipment testing system and method Download PDFInfo
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- CN116491911B CN116491911B CN202310760774.3A CN202310760774A CN116491911B CN 116491911 B CN116491911 B CN 116491911B CN 202310760774 A CN202310760774 A CN 202310760774A CN 116491911 B CN116491911 B CN 116491911B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
- A61B2560/0228—Operational features of calibration, e.g. protocols for calibrating sensors using calibration standards
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02T—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO TRANSPORTATION
- Y02T90/00—Enabling technologies or technologies with a potential or indirect contribution to GHG emissions mitigation
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Abstract
The application relates to the technical field of heart failure monitoring, and provides a heart failure monitoring equipment testing system and a heart failure monitoring equipment testing method. The heart failure monitoring equipment testing system comprises a chest cavity simulation device, a parameter adjusting device and a controller. The chest simulation device comprises a heart simulation unit and a lung simulation unit and is used for simulating the chest of a human body. The parameter adjusting device comprises a first simulation parameter adjusting unit and a second simulation parameter adjusting unit, wherein the first simulation parameter adjusting unit is used for adjusting simulation parameters of the heart simulation unit, and the lung simulation unit is used for adjusting simulation parameters of the lung simulation unit. The controller can set the simulation parameters of the parameter adjusting device to realize different simulation parameter combinations so as to simulate different real chest conditions. The heart failure monitoring equipment monitors the chest simulation device under the combination of different simulation parameters to obtain a plurality of monitoring results, and the controller can verify the monitoring results so as to detect the monitoring accuracy of the heart failure monitoring equipment.
Description
Technical Field
The application relates to the technical field of heart failure monitoring, in particular to a heart failure monitoring equipment testing system and a heart failure monitoring equipment testing method.
Background
In the medical field, heart failure refers to a state where heart disease occurs to the end stage, and is a very serious heart disease. Heart failure patients are generally accompanied by pulmonary effusion and epicardial effusion due to heart failure. These effusions require the patients to take diuretics and other drugs to be discharged in time, otherwise heart failure symptoms can be continuously aggravated. Therefore, the monitoring of the pleural effusion condition of the heart failure patient can well guide the patient to take medicine.
The heart failure monitoring equipment can monitor the pleural effusion condition of heart failure patients in an electromagnetic wave monitoring mode. Electromagnetic wave transmitting and receiving devices can be arranged at the positions of the front chest and the rear chest of the patient corresponding to the lungs, and the condition of hydrothorax in the chest and the lungs is fed back through the change characteristics of electromagnetic waves penetrating through the chest of the patient. Generally, electromagnetic waves pass through liquid products with different proportions, such as water, and the absorption characteristic of water to electromagnetic waves and the dielectric constant characteristic of water are different from those of biological tissues of a human body, so that the relevance of different liquid product levels can be measured in a feedback manner.
However, in order to accurately obtain the pleural effusion, it is necessary to ensure the monitoring accuracy of the heart failure monitoring device. Therefore, the monitoring process of the heart failure monitoring equipment needs to be tested, so that whether the monitoring result of the heart failure monitoring equipment is accurate or not is determined, the heart failure monitoring equipment is adjusted, and the monitoring accuracy is ensured.
Disclosure of Invention
The application provides a heart failure monitoring equipment testing system and a heart failure monitoring equipment testing method, which are used for solving the problem of monitoring accuracy of heart failure monitoring equipment which cannot be tested in the prior art.
In order to solve the technical problems, the embodiment of the application discloses the following technical scheme:
in a first aspect, an embodiment of the present application provides a heart failure monitoring device testing system, including a chest simulation device, a parameter adjusting device, and a controller;
the chest simulation device comprises a heart simulation unit and a lung simulation unit and is used for simulating the chest of a human body;
the parameter adjusting device comprises a first simulation parameter adjusting unit and a second simulation parameter adjusting unit, wherein the first simulation parameter adjusting unit is used for adjusting simulation parameters of the heart simulation unit, and the second simulation parameter adjusting unit is used for adjusting simulation parameters of the lung simulation unit;
the controller is used for setting the simulation parameters of the parameter adjusting device, acquiring a plurality of monitoring results obtained by monitoring the chest cavity simulation device by heart failure monitoring equipment under the combination of different simulation parameters, and checking the monitoring results.
In some embodiments, the cardiac analog unit comprises: a heart chamber simulator and epicardial simulator; the heart chamber simulation device is internally provided with a first simulation liquid, and a second simulation liquid is arranged between the heart chamber simulation device and the epicardium simulation device;
the lung simulation unit comprises: alveolar simulator and pulmonary shell simulator; the pulmonary alveolus simulation device is fixedly arranged in the pulmonary shell simulation device, and the pulmonary shell simulation device is filled with third simulation liquid.
In some embodiments, the first simulation parameter adjustment unit comprises a heart chamber simulator adjustment module;
a first connecting piece is arranged between the heart chamber simulation device adjusting module and the heart chamber simulation device, and the heart chamber simulation device adjusting module is connected with the heart chamber simulation device in a sealing way by the first connecting piece;
the heart chamber simulation device adjusting module provides first simulation liquid for the heart chamber simulation device through the first connecting piece so as to adjust first simulation parameters of the heart chamber simulation device; the first simulation parameters include a simulated heart beat frequency and a simulated heart beat variation ratio.
In some embodiments, the first analog parameter adjustment unit comprises a second analog liquid adjustment module;
a second connecting piece is arranged between the second simulated liquid adjusting module and the epicardium simulating device, and the second connecting piece is used for connecting the second simulated liquid adjusting module with the epicardium simulating device in a sealing way;
the second simulated fluid regulating module is used for providing a second simulated fluid into the epicardium simulator through the second connecting piece so as to regulate a second simulation parameter of the epicardium simulator; the second simulation parameters include a second simulated liquid content.
In some embodiments, a third connector is provided between the second simulation parameter adjustment unit and the alveolar simulator, the third connector sealingly connecting the second simulation parameter adjustment unit and the alveolar simulator;
the second simulation parameter adjusting unit provides filling gas for the alveolus simulation device through a third connecting piece so as to adjust a third simulation parameter of the alveolus simulation device; the third simulated parameters include a simulated respiratory rate, a simulated respiratory waveform, and a simulated respiratory tidal volume.
In some embodiments, further comprising: the simulated lung water proportion adjusting unit is used for simulating the lung water proportion change process when the heart of the human body is weakened; the third simulated liquid comprises a first liquid and a second liquid;
the simulated lung water proportion adjusting unit comprises a third simulated liquid supply module and a liquid filtering module; the third simulation liquid supply module is connected with one end of the lung shell simulation device in a sealing way and is used for supplying the third simulation liquid into the lung shell simulation device; the liquid filtering module is connected with the other end of the lung shell simulation device and is used for filtering first liquid in the lung shell simulation device to the outside of the chest cavity simulation device and keeping second liquid in the lung shell simulation device.
In some embodiments, the chest simulation device further comprises: simulating a chest shell; the simulated chest shell is used for packaging the first simulated parameter adjusting unit and the second simulated parameter adjusting unit; the simulated chest housing is filled with a fourth simulated fluid.
In some embodiments, the simulated chest housing comprises: a first housing and a second housing; the first shell is made of flexible materials, and the second shell is made of rigid materials;
the liquid filtration module is disposed in the second housing, and the lung housing simulation device and the second housing are connected at the liquid filtration module.
In some embodiments, the verifying the monitoring result is further configured to:
obtaining target simulation parameters, wherein the target simulation parameters are simulation parameters of the parameter adjusting device in the current monitoring process;
acquiring a target qualified interval corresponding to the target simulation parameter based on a qualified interval database;
and acquiring a verification result of the monitoring result based on the target qualified interval, wherein the verification result is used for representing whether the monitoring result is in the target qualified interval or not.
In a second aspect, an embodiment of the present application provides a method for testing a heart failure monitoring device, where the method includes:
setting simulation parameters;
based on the set simulation parameters, adjusting the simulation parameters of the heart simulation unit and the simulation parameters of the lung simulation unit;
obtaining a plurality of monitoring results obtained by monitoring the chest cavity simulation device by the heart failure monitoring equipment under the combination of different simulation parameters;
and checking the monitoring result.
According to the technical scheme, the application provides a heart failure monitoring equipment testing system and a heart failure monitoring equipment testing method. The heart failure monitoring equipment testing system comprises a chest cavity simulation device, a parameter adjusting device and a controller. The chest simulation device comprises a heart simulation unit and a lung simulation unit and is used for simulating the chest of a human body. The parameter adjusting device comprises a first simulation parameter adjusting unit and a second simulation parameter adjusting unit, wherein the first simulation parameter adjusting unit is used for adjusting simulation parameters of the heart simulation unit, and the lung simulation unit is used for adjusting simulation parameters of the lung simulation unit. The controller can set the simulation parameters of the parameter adjusting device to realize different simulation parameter combinations so as to simulate different real chest conditions. The heart failure monitoring equipment monitors the chest simulation device under the combination of different simulation parameters to obtain a plurality of monitoring results, and the controller can verify the monitoring results so as to detect the monitoring accuracy of the heart failure monitoring equipment.
Drawings
In order to more clearly illustrate the technical solution of the present application, the drawings that are needed in the embodiments will be briefly described below, and it will be obvious to those skilled in the art that other drawings can be obtained from these drawings without inventive effort.
FIG. 1 illustrates an overall schematic of a chest simulation device in some embodiments;
FIG. 2 illustrates an overall schematic of a center decay monitoring apparatus test system in accordance with some embodiments;
FIG. 3 illustrates a schematic diagram of lung water ratio variation in some embodiments;
FIG. 4 illustrates a schematic diagram of monitoring results and pass intervals in some embodiments.
Detailed Description
Reference will now be made in detail to the embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, the same numbers in different drawings refer to the same or similar elements, unless otherwise indicated. The embodiments described in the examples below do not represent all embodiments consistent with the application. Merely exemplary of apparatus and methods consistent with some aspects of the application as set forth in the claims.
Based on the exemplary embodiments described herein, all other embodiments that may be obtained by one of ordinary skill in the art without making any inventive effort are within the scope of the appended claims. Furthermore, while the present disclosure has been described in terms of an exemplary embodiment or embodiments, it should be understood that each aspect of the disclosure can be practiced separately from the other aspects.
It should be noted that the brief description of the terminology in the present application is for the purpose of facilitating understanding of the embodiments described below only and is not intended to limit the embodiments of the present application. Unless otherwise indicated, these terms should be construed in their ordinary and customary meaning.
The terms first, second, third and the like in the description and in the claims and in the above-described figures are used for distinguishing between similar or similar objects or entities and not necessarily for describing a particular sequential or chronological order, unless otherwise indicated (Unless otherwise indicated). It is to be understood that the terms so used are interchangeable under appropriate circumstances such that the embodiments of the application are, for example, capable of operation in sequences other than those illustrated or otherwise described herein.
Furthermore, the terms "comprise" and "have," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a product or apparatus that comprises a list of elements is not necessarily limited to those elements expressly listed, but may include other elements not expressly listed or inherent to such product or apparatus.
The term "module" as used in this disclosure refers to any known or later developed hardware, software, firmware, artificial intelligence, fuzzy logic, or combination of hardware and/or software code that is capable of performing the function associated with that element.
In order to monitor the pleural effusion of patients with heart failure, heart failure monitoring devices may be used. Electromagnetic wave transmitting and receiving devices can be arranged at positions of the front chest and the rear chest of the patient corresponding to the lungs, and the condition of hydrothorax and pulmonary effusion is fed back through the changing characteristics of electromagnetic waves penetrating through the chest of the patient. In order to accurately acquire the pleural effusion condition, the monitoring accuracy of heart failure monitoring equipment needs to be ensured. Therefore, the monitoring process of the heart failure monitoring equipment needs to be tested, so that whether the monitoring result of the heart failure monitoring equipment is accurate or not is determined, the heart failure monitoring equipment is adjusted, and the monitoring accuracy is ensured.
The embodiment of the application provides a heart failure monitoring equipment testing system which is used for testing the monitoring accuracy of heart failure monitoring equipment. The heart failure monitoring equipment test system can simulate the real conditions of various human chest cavities, the heart failure monitoring equipment can monitor the pleural effusion level in the heart failure monitoring equipment test system, and the heart failure monitoring equipment test system can verify the monitoring result of the heart failure monitoring equipment, so that the monitoring accuracy of the heart failure monitoring equipment is determined, and the function of equipment test is achieved.
In the embodiment of the application, the heart failure monitoring equipment test system can comprise a chest simulation device, a parameter adjusting device and a controller.
The chest simulator can be used for simulating the real human chest, including the internal composition of the human chest. The heart failure monitoring equipment can monitor the chest simulation device to simulate and test the chest of a human body, so that a monitoring result is obtained. The chest simulation device may comprise a heart simulation unit and a lung simulation unit. Considering that heart failure monitoring equipment is used for testing pleural effusion, pleural effusion comprises pulmonary effusion and epicardial effusion, the chest of a human body containing the pleural effusion can be simulated by simulating the heart part and the lung of the human body.
Considering the differences of the chest conditions of human bodies under different states, for example, different people, the chest conditions are different, and the differences of the heart beating conditions and the lung breathing conditions can be represented. Alternatively, the chest condition may be different for the same individual in different health conditions, and may be manifested by different levels of pleural effusion. Therefore, the parameters of the thoracic cavity simulation device can be adjusted by the parameter adjusting device, so that different thoracic cavity conditions can be simulated. For example, the heart beat condition, the lung breathing condition, and the pleural effusion content can be varied to simulate various chest conditions.
The parameter adjusting means may comprise a first analog parameter adjusting unit and a second analog parameter adjusting unit. The first simulation parameter adjusting unit is used for adjusting simulation parameters of the heart simulation unit to adjust heart conditions, such as heart beating conditions and heart effusion conditions. The second simulation parameter adjusting unit is used for adjusting simulation parameters of the lung simulation unit to adjust lung conditions, for example, lung breathing conditions can be adjusted. The heart simulation unit and the lung simulation unit may be under a combination of a plurality of different simulation parameters, thereby simulating a plurality of chest conditions.
The controller can control the working process of the heart failure monitoring equipment testing system, for example, different simulation parameters can be set for the parameter adjusting device, so that the parameter adjusting device can adjust the simulation parameter conditions of the chest simulation device according to the set simulation parameter combination so as to simulate different chest conditions.
After the simulation parameters are set, the heart failure monitoring equipment can monitor the thoracic cavity simulation device, so that a monitoring result of the pleural effusion is obtained. It should be noted that the chest simulator can correspond to the combination of multiple different simulation parameters, and the heart failure monitoring device can monitor the chest simulator under each simulation parameter combination respectively to obtain the monitoring result of each condition. The controller can acquire a plurality of monitoring results and check the monitoring results so as to test the monitoring accuracy of the heart failure monitoring equipment.
FIG. 1 illustrates an overall schematic of a chest simulator in some embodiments. As shown in fig. 1, the chest simulator includes a heart simulation unit and a lung simulation unit for simulating the heart and the lung of a human body, respectively.
The chest simulator simulates the real chest of a human body, and the heart failure monitoring equipment can monitor the chest simulator. The heart failure monitoring equipment comprises a transmitting and receiving device 1-1 which can be arranged on the front side and the rear side of the chest cavity simulation device, respectively transmits electromagnetic waves to the chest cavity simulation device and receives the electromagnetic waves penetrating through the chest cavity simulation device, so that the electromagnetic waves determine the hydrops condition in the chest cavity simulation device.
The chest simulator may comprise a simulated chest housing 2 for simulating a human chest. The simulated chest housing 2 is the outer contour of the chest simulator and is used to enclose the heart and lung simulation units inside the chest simulator. The simulated thoracic housing 2 is filled with a fourth simulated fluid 3, and the fourth simulated fluid 3 is filled between the simulated thoracic housing 2 and the heart and lung simulation units. The fourth simulation liquid 3 is used for simulating internal tissues of a human body and can also play a role in buffering a heart simulation unit and a lung simulation unit. In some embodiments, the fourth simulated liquid 3 is a liquid, and 0.9% NaCl brine may be used.
The lung simulation unit includes: a lung housing simulation means 4, a third simulation liquid 5 and an alveolus simulation means 6. The lung housing simulation device 4 is used for simulating the lung housing of a human body, and may be made of a flexible material with elasticity, for example, may be made of latex or rubber material, so as to ensure that the lung simulation unit can expand and contract. The lung housing simulation device 4 can expand in a diastole when the internal pressure increases and contract again when the internal pressure decreases, thereby simulating the lung breathing situation.
The third simulation liquid 5 is used for simulating lung tissue, for example, simulating lung tissue liquid, and may be a solution formed by dissolving a polymer material in 0.9% NaCl saline, where the polymer material may be xanthan gum, and the ratio of the xanthan gum may be 10%. The third simulation liquid 5 fills between the lung housing simulation device 4 and the alveolus simulation device 6 and may buffer the alveolus simulation device 6.
The number of alveolus simulation devices 6 may be set to be plural and provided in the lung housing simulation device 4. To avoid the movement of the alveolus simulation device 6 back and forth in the lung housing simulation device 4, the alveolus simulation device 6 may be fixedly arranged in the lung housing simulation device 4, for example by means of connecting wires to the inner wall of the lung housing simulation device 4. The alveolar simulator 6 may be formed by wrapping an alveolar simulator outer wall 7, and the alveolar simulator outer wall 7 may be a flexible material, for example, may be made of latex or rubber material. A filling gas, such as air, may be included in the alveolar simulator outer wall 7 to simulate a real alveolar condition. The alveolar simulator outer wall 7 expands in a diastole when the internal pressure increases, and contracts again when the internal pressure decreases.
In some embodiments, the cardiac analog unit comprises: epicardial simulator 8 and epicardial simulator. The epicardial simulator 8 is used to simulate the epicardium and may be a flexible material, such as latex or rubber material, to simulate a real breathing situation. The heart chamber simulation device is used for simulating a heart chamber of a human body. A second simulation fluid 9 may be provided between the epicardial simulator 8 and the endocardial simulator, the second simulation fluid 9 being used to simulate epicardial fluid present in a heart failure patient. The second simulated liquid 9 may be 0.9% NaCl brine.
The heart chamber simulator comprises a heart chamber simulator outer wall 10 and a first simulator fluid 11. The outer wall 10 of the heart chamber simulator is used for simulating the outer wall of the heart chamber, and may be made of an elastic soft material, for example, latex or rubber material. Which expands upon inflation of the internal pressure and contracts upon deflation of the internal pressure. The first simulation liquid 11 may simulate heart blood of a human body. The first simulated liquid 11 may be a solution of 10% xanthan gum dissolved in 0.9% NaCl brine. The heart chamber simulator outer wall 10 and the first simulator fluid 11 together simulate a human heart chamber, including the myocardium and heart blood.
FIG. 2 illustrates an overall schematic of a center decay monitoring apparatus test system in accordance with some embodiments. As shown in fig. 2, a parameter adjustment device may be coupled to the chest simulator to adjust the simulation parameters of the chest simulator.
The first simulation parameter adjustment unit may comprise a heart chamber simulator adjustment module. The heart chamber simulation device adjusting module can adjust simulation parameters of the heart simulation unit to simulate different heart beating conditions.
A first connector 14 may be provided between the heart chamber simulator adjustment module and the heart chamber simulator. The first connector 14 may be a rigid connection tube for communicating the chamber simulator adjustment module with the chamber simulator. In order to avoid leakage of the first simulation liquid 11 in the heart chamber simulator outside the heart chamber simulator, the first connection 14 may connect the heart chamber simulator adjustment module and the heart chamber simulator in a sealed manner. One end of the first connecting piece 14 can be in sealing connection with the outer wall 10 of the heart chamber simulating device, and the other end of the first connecting piece can be in sealing connection with the adjusting module of the heart chamber simulating device.
The heart chamber simulator adjustment module may provide the first simulated fluid 11 to the heart chamber simulator via the first connector 14. By adjusting the process of supplying the first simulation liquid 11, the simulation parameters corresponding to the heart chamber simulation device, which in the present embodiment are referred to as first simulation parameters, can be adjusted. The first simulation parameters may include a simulated heart beat frequency and a simulated heart beat variation ratio. Wherein, the simulated heart beat frequency is used for simulating the real heart beat frequency, and the simulated heart beat change proportion is used for simulating the real heart beat change proportion.
The heart chamber simulator adjustment module may inject the first simulated fluid 11 into the heart chamber simulator through the first connection 14 until the heart chamber simulator is filled.
The heart chamber simulator regulating module may change the hydraulic pressure inside the heart chamber simulator to control the expansion, expansion and contraction process of the heart chamber simulator. During operation, the heart chamber simulator regulating module can extract part of the first simulation liquid 11 and then inject part of the first simulation liquid 11, and simulate a real heart beating scene by circulating the above process. At the same time, the frequency of the simulated heart beat can be adjusted by varying the frequency of the hydraulic pressure variation, i.e. the frequency of the extraction injection of the first simulated liquid 11. By varying the amplitude of the hydraulic pressure variation, i.e. the amount of the first simulation liquid 11 injected by extraction, the ratio of the simulated heart beat variation can be adjusted, enabling the adjustment of the first simulation parameter.
In some embodiments, the first analog parameter adjustment unit may further comprise a second analog liquid adjustment module. The second simulated fluid conditioning module may condition the simulation parameters of the cardiac simulation unit to simulate different epicardial fluid conditions.
A second connection 15 may be provided between the second analog fluid regulating module and the epicardial simulator 8. The second connection 15 may be a rigid connection tube for communicating the second analog fluid regulating module with the epicardial simulator 8. The second connection 15 may sealingly connect the second analog fluid regulation module to the epicardial simulator 8 to avoid leakage of the second analog fluid 9 out of the epicardial simulator 8. One end of the second connecting piece 15 may be in sealing connection with the epicardial simulator 8, and the other end may be in sealing connection with the second analog fluid regulating module.
The second analogue liquid conditioning module may provide a second analogue liquid 9 to the epicardial analogue means 8 via a second connector 15. By adjusting the procedure of providing the second simulation liquid 9, the simulation parameters of the epicardial simulator 8, in the present embodiment referred to as second simulation parameters, can be adjusted. The second simulation parameter includes a second simulated liquid content.
The second simulation liquid conditioning module may inject a second simulation liquid 9 into the epicardial simulator 8 via a second connection 15. Meanwhile, the second simulation liquid adjusting module can adjust the second simulation parameters by changing the content of the injected second simulation liquid 9 so as to simulate different epicardial effusion conditions.
In some embodiments, a third connection may be provided between the second simulation parameter adjustment unit and the alveolar simulation 6. Each alveolar simulator 6 can be connected to the second simulation parameter adjusting unit via a third connection, which can be made of flexible material, considering that the number of alveolar simulators can be large. The third connector may sealingly connect the second simulation parameter tuning unit to the alveolar simulator.
The second simulation parameter adjusting unit may provide a filling gas, e.g. air, to the alveolar simulation 6 via the third connection. The second simulation parameter adjusting unit may adjust the simulation parameters of the alveolar simulation by adjusting the process of supplying the filling gas, which is referred to as a third simulation parameter in the embodiment of the present application. The third simulation parameters can include a simulated respiratory rate, a simulated respiratory waveform and a simulated respiratory tidal volume, which respectively simulate the respiratory rate respiratory waveform and the respiratory tidal volume when the human body breathes.
The second simulation parameter adjusting unit may adjust the air pressure conditions in the alveolar simulator 6 to simulate the pulmonary breathing process. After the second simulation parameter adjusting unit injects air into the alveolar simulator 6, the process of extracting the injected air may be repeated to control the diastole and the systole of the alveolar simulator 6. Upon adjustment, the frequency of the diastolic contraction, the waveform of the alveolar simulator 6, and the tidal volume of the alveolar simulator 6 changes may be controlled to adjust the third simulation parameter.
It should be noted that, when the simulation parameters are adjusted, one of the simulation parameters may be changed, or a plurality of simulation parameters may be changed, so as to implement different combinations of simulation parameters and simulate different chest conditions.
In some embodiments, the heart failure monitoring device testing system further comprises a simulated lung water proportion adjustment unit. The simulated lung water proportion adjusting unit can simulate the lung water proportion change process during heart failure of a human body. When heart failure occurs in a human body, the lung water proportion in the chest cavity may become more, meanwhile, the lung water proportion may become larger gradually along with the aggravation of the heart failure severity, and when the heart failure severity is weakened, the lung water proportion may be reduced. The simulated lung water proportion adjusting unit can adjust the content of the simulated lung water in the lung simulating unit, so that the heart failure process is simulated.
The third simulation liquid 5 may include therein a first liquid and a second liquid. Wherein the first fluid may simulate lung water and the second fluid may simulate lung tissue. Taking a solution of 10% xanthan gum dissolved in 0.9% NaCl brine as an example, the NaCl brine may be the first liquid and the xanthan gum may be the second liquid.
The simulated lung water proportion adjustment unit may comprise a third simulated liquid supply module and a liquid filtration module 13. Wherein the third simulation liquid supply module is in sealing connection with one end of the lung housing simulation device 4, and the third simulation liquid 5 can be supplied into the lung housing simulation device 4.
The liquid filtering module 13 is connected to the other end of the lung housing simulation device 4, and can filter the first liquid in the lung housing simulation device 4 out of the chest cavity simulation device and retain the second liquid in the lung housing simulation device 4. The liquid filtration module 13 may be a filter membrane that may allow passage of the NaCl brine but not the polymeric material components, thereby effecting filtration of the NaCl brine from the lung housing analog device 4 and retention of the xanthan gum. In some embodiments, the liquid filtration module 13 may employ a hydrophilic PTFE membrane with a membrane material of 0.22 μm.
The first liquid in the third simulation liquid 5 can flow out of the chest simulation device through the liquid filtration module 13 to form a filtered liquid 16, and the filtered liquid 16 can be collected by a recovery container. At the same time, as the first liquid flows out of the lung housing simulation device 4, the volume of the lung simulation unit may decrease and the third simulation liquid supply module may continue to inject the third simulation liquid 5 into the lung simulation unit. The above-mentioned process of filtering the first liquid and replenishing the third simulation liquid 5 results in that the proportion of the polymer material in the pulmonary simulation unit is also increased synchronously, and the proportion of the water in the NaCl brine is decreased synchronously until the exuded NaCl brine is not filtered. The process of changing the proportion of the two liquids is a process simulating the proportion of lung water. Fig. 3 shows a schematic representation of lung water ratio variation in some embodiments. As shown in fig. 3, the NaCl saline mimics the lung water, and the lung water gradually decreases with time, resulting in a continuously decreasing proportion of the lung water.
In some embodiments, the simulated chest housing 2 comprises: a first housing and a second housing 12. Wherein the first housing is a flexible material and the second housing is a rigid material. The first housing may be an upper housing of a chest simulation device for enclosing a heart simulation unit and a lung simulation unit. By providing the first housing of a flexible material, which allows for possible expansion and contraction of the heart and lung simulation units, the volume changes, which may be a function of the course of the heart and lung simulation units, to avoid affecting the course of the heart and lung simulation units.
The liquid filtering module 13 may be disposed in the second housing 12. Wherein the lung housing simulation device 4 and the second housing 12 may be connected at a fluid filter module 13, thereby ensuring that the first fluid in the lung housing simulation device 4 may flow out of the chest cavity simulation device through the fluid filter module 13. The second housing 12 may also isolate the fourth analog liquid 3 from the filtered liquid 16.
In some embodiments, different chest conditions are simulated by adjusting the simulation parameters to make up different combinations of simulation parameters. The heart failure monitoring equipment can monitor the chest simulation device to obtain a monitoring result. The monitoring result may be a change curve for characterizing the relation between the effusion measurement and time.
The controller can verify the monitoring result to test the monitoring accuracy of the heart failure monitoring equipment.
The controller may first obtain the target simulation parameters. The target simulation parameters are simulation parameters set in the parameter adjusting device in the current monitoring process, and include a first simulation parameter of the heart chamber simulation device, a second simulation parameter of the epicardium simulation device 8 and a third simulation parameter of the alveolus simulation device 6.
The controller can acquire a target qualified interval corresponding to the target simulation parameter based on the qualified interval database. For each simulation parameter combination, the qualified interval data corresponding to the simulation parameter combination can be stored in the qualified interval database in advance. The qualified interval is used for representing the interval range of qualified monitoring results. The qualified interval can be determined according to the real pleural effusion change condition of the human body clinically. FIG. 4 illustrates a schematic diagram of monitoring results and pass intervals in some embodiments. As shown in fig. 4, the monitoring result curve is located in the qualified interval, which indicates that the heart failure monitoring device passes the test, that is, the test is qualified.
The controller may obtain a verification result of the monitoring result based on the target pass interval, the verification result being used to characterize whether the monitoring result is within the target pass interval. If the monitoring result is in the target qualified interval, the current monitoring result is accurate, the simulation parameter combination of the chest simulation device can be adjusted to simulate a new chest condition, and the chest simulation device is monitored again by using the heart failure monitoring equipment so as to continuously test the heart failure monitoring equipment. A test threshold may be set, and if the heart failure monitoring device detects that the accurate continuous number of times reaches the test threshold, the heart failure monitoring device is considered to pass the test.
If the monitoring result of the heart failure monitoring equipment is not in the target qualified interval, the problem of the monitoring accuracy of the heart failure monitoring equipment is described, and the heart failure monitoring equipment can be corrected at the moment.
The embodiment of the application also provides a heart failure monitoring equipment testing method which can be applied to a heart failure monitoring equipment testing system. The method comprises the following steps:
setting simulation parameters;
based on the set simulation parameters, adjusting the simulation parameters of the heart simulation unit and the simulation parameters of the lung simulation unit;
obtaining a plurality of monitoring results obtained by monitoring the chest cavity simulation device by the heart failure monitoring equipment under the combination of different simulation parameters;
and checking the monitoring result.
Embodiments of the present application also provide a computer-readable storage medium having a computer program stored thereon. When the computer program is called by the processor, the steps in the heart failure monitoring device testing method as described above can be implemented.
Since the foregoing embodiments are all described in other modes by reference to the above, the same parts are provided between different embodiments, and the same and similar parts are provided between the embodiments in the present specification. And will not be described in detail herein.
It will be apparent to those skilled in the art that the techniques of embodiments of the present application may be implemented in software plus a necessary general purpose hardware platform. Based on such understanding, the technical solutions in the embodiments of the present application may be embodied essentially or in parts contributing to the prior art in the form of a software product, which may be stored in a storage medium, such as a ROM/RAM, a magnetic disk, an optical disk, etc., including several instructions to cause a computer device (which may be a personal computer, a server, or a network device, etc.) to execute the method of the embodiments or some parts of the embodiments of the present application.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present application, and not for limiting the same; although the application has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the application.
The foregoing description, for purposes of explanation, has been presented in conjunction with specific embodiments. However, the illustrative discussions above are not intended to be exhaustive or to limit the embodiments to the precise forms disclosed above. Many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles and the practical application, to thereby enable others skilled in the art to best utilize the embodiments and various embodiments with various modifications as are suited to the particular use contemplated. This application is intended to cover any variations, uses, or adaptations of the application following, in general, the principles of the application and including such departures from the present disclosure as come within known or customary practice within the art to which the application pertains. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the application being indicated by the following claims. The embodiments of the present application described above do not limit the scope of the present application.
Claims (9)
1. The heart failure monitoring equipment testing system is characterized by comprising a chest simulation device, a parameter adjusting device and a controller;
the chest simulation device comprises a heart simulation unit and a lung simulation unit and is used for simulating the chest of a human body; the heart simulation unit comprises a heart cavity simulation device and an epicardium simulation device; the lung simulation unit comprises an alveolus simulation device and a lung shell simulation device; the lung shell simulation device is filled with a third simulation liquid, and the third simulation liquid comprises a first liquid and a second liquid;
the parameter adjusting device comprises a first simulation parameter adjusting unit, a second simulation parameter adjusting unit and a simulation lung water proportion adjusting unit, wherein the first simulation parameter adjusting unit is used for adjusting simulation parameters of the heart simulation unit, the second simulation parameter adjusting unit is used for adjusting simulation parameters of the lung simulation unit, and the simulation lung water proportion adjusting unit is used for simulating a lung water proportion changing process when a human body is in heart failure;
the heart chamber simulation device comprises first simulation parameters, wherein the first simulation parameters comprise a simulated heart beat frequency and a simulated heart beat change proportion; the epicardial simulator includes a second simulation parameter, the second simulation parameter including a second simulated fluid content; the alveolar simulator includes a third simulation parameter; the third simulation parameters comprise a simulation respiratory frequency, a simulation respiratory waveform and a simulation respiratory tidal volume;
the simulated lung water proportion adjusting unit comprises a third simulated liquid supply module and a liquid filtering module; the third simulation liquid supply module is connected with one end of the lung shell simulation device in a sealing way and is used for supplying the third simulation liquid into the lung shell simulation device; the liquid filtering module is connected with the other end of the lung shell simulation device and is used for filtering first liquid in the lung shell simulation device out of the chest cavity simulation device and retaining second liquid in the lung shell simulation device;
the controller is used for setting the simulation parameters of the parameter adjusting device, acquiring a plurality of monitoring results obtained by monitoring the chest cavity simulation device by heart failure monitoring equipment under the combination of different simulation parameters, and checking the monitoring results.
2. The heart failure monitoring device testing system of claim 1, wherein a first simulated fluid is disposed in the heart chamber simulator, and a second simulated fluid is disposed between the heart chamber simulator and the epicardial simulator;
the pulmonary alveolus simulation device is fixedly arranged in the pulmonary shell simulation device.
3. The heart failure monitoring device testing system of claim 2, wherein the first simulation parameter adjustment unit includes a heart chamber simulator adjustment module;
a first connecting piece is arranged between the heart chamber simulation device adjusting module and the heart chamber simulation device, and the heart chamber simulation device adjusting module is connected with the heart chamber simulation device in a sealing way by the first connecting piece;
the heart chamber simulator adjustment module provides first simulation liquid for the heart chamber simulator through the first connecting piece so as to adjust first simulation parameters of the heart chamber simulator.
4. The heart failure monitoring device testing system of claim 2, wherein the first analog parameter adjustment unit includes a second analog fluid adjustment module;
a second connecting piece is arranged between the second simulated liquid adjusting module and the epicardium simulating device, and the second connecting piece is used for connecting the second simulated liquid adjusting module with the epicardium simulating device in a sealing way;
the second simulated fluid adjustment module provides a second simulated fluid to the epicardial simulator via the second connection to adjust a second simulation parameter of the epicardial simulator.
5. The heart failure monitoring device testing system of claim 2, wherein,
a third connecting piece is arranged between the second simulation parameter adjusting unit and the alveolus simulation device, and the third connecting piece is used for connecting the second simulation parameter adjusting unit and the alveolus simulation device in a sealing way;
the second simulation parameter adjusting unit supplies a filling gas to the alveolar simulator through a third connection to adjust a third simulation parameter of the alveolar simulator.
6. The heart failure monitoring device testing system of claim 1, wherein the chest simulation arrangement further comprises: simulating a chest shell; the simulated chest shell is used for packaging the first simulated parameter adjusting unit and the second simulated parameter adjusting unit; the simulated chest housing is filled with a fourth simulated fluid.
7. The heart failure monitoring device testing system of claim 6, wherein the simulated chest housing comprises: a first housing and a second housing; the first shell is made of flexible materials, and the second shell is made of rigid materials;
the liquid filtration module is disposed in the second housing, and the lung housing simulation device and the second housing are connected at the liquid filtration module.
8. The heart failure monitoring device testing system of claim 1, wherein the verifying the monitoring result is further configured to:
obtaining target simulation parameters, wherein the target simulation parameters are simulation parameters of the parameter adjusting device in the current monitoring process;
acquiring a target qualified interval corresponding to the target simulation parameter based on a qualified interval database;
and acquiring a verification result of the monitoring result based on the target qualified interval, wherein the verification result is used for representing whether the monitoring result is in the target qualified interval or not.
9. The heart failure monitoring equipment testing method is characterized by being applied to a heart failure monitoring equipment testing system, wherein the heart failure monitoring equipment testing system comprises a chest cavity simulation device, a parameter adjusting device and a controller; the chest simulation device comprises a heart simulation unit and a lung simulation unit and is used for simulating the chest of a human body; the heart simulation unit comprises a heart cavity simulation device and an epicardium simulation device; the lung simulation unit comprises an alveolus simulation device and a lung shell simulation device; the lung shell simulation device is filled with a third simulation liquid, and the third simulation liquid comprises a first liquid and a second liquid; the parameter adjusting device comprises a first simulation parameter adjusting unit, a second simulation parameter adjusting unit and a simulation lung water proportion adjusting unit, wherein the first simulation parameter adjusting unit is used for adjusting simulation parameters of the heart simulation unit, the second simulation parameter adjusting unit is used for adjusting simulation parameters of the lung simulation unit, and the simulation lung water proportion adjusting unit is used for simulating a lung water proportion changing process when a human body is in heart failure; the heart chamber simulation device comprises first simulation parameters, wherein the first simulation parameters comprise a simulated heart beat frequency and a simulated heart beat change proportion; the epicardial simulator includes a second simulation parameter, the second simulation parameter including a second simulated fluid content; the alveolar simulator includes a third simulation parameter; the third simulation parameters comprise a simulation respiratory frequency, a simulation respiratory waveform and a simulation respiratory tidal volume; the simulated lung water proportion adjusting unit comprises a third simulated liquid supply module and a liquid filtering module; the third simulation liquid supply module is connected with one end of the lung shell simulation device in a sealing way and is used for supplying the third simulation liquid into the lung shell simulation device; the liquid filtering module is connected with the other end of the lung shell simulation device and is used for filtering first liquid in the lung shell simulation device out of the chest cavity simulation device and retaining second liquid in the lung shell simulation device;
the method comprises the following steps:
setting simulation parameters;
based on the set simulation parameters, adjusting the simulation parameters of the heart simulation unit and the simulation parameters of the lung simulation unit;
obtaining a plurality of monitoring results obtained by monitoring the chest cavity simulation device by the heart failure monitoring equipment under the combination of different simulation parameters;
and checking the monitoring result.
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| WO1997037589A1 (en) * | 1996-04-04 | 1997-10-16 | Merck & Co., Inc. | Model of heart failure |
| US5906207A (en) * | 1996-04-04 | 1999-05-25 | Merck & Co., Inc. | Method for simulating heart failure |
| CN111084674A (en) * | 2020-01-06 | 2020-05-01 | 清华大学 | In-vitro simulation circulation system for artificial heart test |
| CN114699646A (en) * | 2022-03-25 | 2022-07-05 | 上海东心生物医疗科技有限公司 | Performance test system for ventricular assist device |
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| WO1997037589A1 (en) * | 1996-04-04 | 1997-10-16 | Merck & Co., Inc. | Model of heart failure |
| US5906207A (en) * | 1996-04-04 | 1999-05-25 | Merck & Co., Inc. | Method for simulating heart failure |
| CN111084674A (en) * | 2020-01-06 | 2020-05-01 | 清华大学 | In-vitro simulation circulation system for artificial heart test |
| CN114699646A (en) * | 2022-03-25 | 2022-07-05 | 上海东心生物医疗科技有限公司 | Performance test system for ventricular assist device |
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