CN116473066A - Insecticidal composition - Google Patents

Abstract

The invention relates to an insecticidal composition which contains active ingredients of a compound shown as a formula I and a compound II, wherein the compound II is selected from trifluoro-phenylpyrimidine, thiocyclam, antifeedant hydrazine and bromantraniliproleAt least one of the amides. The invention also relates to the use of the insecticidal composition for preventing or controlling insects of the families of the borer moth, plutellaceae, noctuid, leaf beetle, plant hopper, aphid and leaf beetle.

Description

Insecticidal composition

The application is a divisional application with the application number of 201910932239.5, the application date of 2019, 9 and 29, and the name of the divisional application of 'an insecticidal composition'.

Technical Field

The present invention relates to a pesticidal composition which is highly effective for controlling animal pests.

Background

The most typical problem in animal pest control is the need to reduce the dosage rate of the active ingredient to reduce or avoid adverse environmental or toxicological effects while still providing effective animal pest control effects.

Another difficulty with pest control is that repeated and unique use of a single pesticidal active ingredient in many cases results in a rapid selection of pests that produce natural or adaptive resistance to the active ingredient.

Due to the multiple generations and adaptation of the pests, the resistance of the pests is established in a relatively short time. There is also a need for pest control agents that have an effect on both pests and their larvae and eggs, which have superior penetration.

In addition, in pest control, there is also a need to combine knockdown activity with prolonged control time, i.e., rapid action and long-acting action.

The active ingredients of formula I are known from WO 2007/144100. However, the insecticidal/acaricidal efficacy of the known compounds and/or their activity spectrum and/or their compatibility with plants (in particular with crop plants) is not always sufficient.

Disclosure of Invention

It is an object of the present invention to provide a pesticidal composition which solves at least one of the problems such as improving biological properties, providing synergistic properties, lowering dose rates, expanding activity spectrum, combining knockdown activity with long acting effects, resistance management to delay resistance.

The present invention has unexpectedly found that combining a compound of formula I with a compound II selected from one of trifluoperazine, thiocyclam, imazalil, bromaroxad, is effective in preventing or controlling animal pests and their larvae and eggs. Surprisingly, it has been found that the simultaneous (i.e., combined or separate) application of the active compounds of formula I and compound II or the sequential application of the compounds of formula I and compound II gives enhanced pest control effects compared to the possible control rates of the individual compounds, which unexpected effect is a true synergistic effect, not just the addition of the activities.

The invention relates to an insecticidal composition, which is realized by adopting the following technical scheme:

an insecticidal composition comprising the active ingredients of a compound of formula I and a compound II selected from one of the following compounds: trifluoro-benzene pyrimidine, thiocyclam, hydrazine-inhibiting and bromarone-fluorobenzene bisamide.

The compound II is selected from trifluoro-phenylpyrimidine.

The compound II is selected from the thiocyclam.

The compound II is selected from the group consisting of antifeedant hydrazine.

The compound II is selected from bromothalonil fluorobenzamide.

The weight ratio of the compound of formula I to the compound II is 50:1 to 1:300, preferably 25:1 to 1:200, preferably 10:1 to 1:150, more preferably 10:1 to 1:100, more preferably 10:1 to 1:50.

The weight ratio of the compound of formula I and compound II according to the invention may also be, for example, 50:1, 40:1, 30:1, 20:1, 10:1, 5:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:13, 1:15, 1:18, 1:20, 1:25, 1:28, 1:30, 1:35, 1:40, 1:45, 1:50, 1:55, 1:60, 1:65, 1:70, 1:75, 1:80, 1:85, 1:90, 1:95, 1:100, 1:120, 1:150, 1:160, 1:180, 1:200, 1:220, 1:250, 1:280, 1:300.

An insecticidal composition comprising the active compounds of formula I and compound II, the weight of the compounds of formula I and compound II together comprising from 1% to 90%, preferably from 5% to 80%, more preferably from 5% to 70%, still more preferably from 5% to 60%, more preferably from 5% to 50% by weight of the insecticidal composition.

An insecticidal composition comprising the active compounds of formula I and compound II, the weight of the compounds of formula I and compound II together comprising, for example, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90% by weight of the insecticidal composition.

An insecticidal composition comprising the active ingredients of a compound of formula I and a compound II, the insecticidal composition further comprising a surfactant and/or a filler.

The insecticidal composition is in the forms of emulsifiable concentrate, water suspending agent, oil suspending agent, seed treatment dry powder, seed treatment suspending agent, water dispersible granule, wettable powder, suspending agent, aerosol, coated granule, extruded granule, aqueous emulsion, microcapsule suspending agent, dry suspending agent, ultra-low volume liquid, electrostatic oil agent, gel, granule and microparticle.

The insecticidal compositions of the present invention may be applied undiluted or diluted with water.

The insecticidal composition of the present invention surprisingly exhibits extremely high activity in the treatment of plants, plant propagation material, soil in which plants are grown, for the prevention or control of pests and their larvae and eggs.

The insecticidal composition of the present invention has excellent control efficacy against pests and their larvae and eggs at low doses.

In another aspect, the invention also provides the use of a pesticidal composition for the prevention or control of pests and their larvae and eggs.

In particular, the invention provides the use of an insecticidal composition for preventing or controlling insects of the families of the family of the borer, the family of the plutellaceae, the family of the noctuid, the family of the leaf beetles, the family of the plant hoppers, the family of the aphids and the family of the leaf spider.

More particularly, the present invention provides a use of an insecticidal composition for preventing or controlling myzus persicae, cotton aphid, peach aphid, plutella xylostella, asparagus caterpillar, spodoptera frugiperda, cotton bollworm, chilo suppressalis, leaf roller of rice, phyllotreta striolata, ape leaf worm, leaf scald mite pest and larvae and eggs thereof.

The use of the insecticidal composition according to the invention for treating seed to prevent attack of the seed by pests.

The insecticidal composition of the present invention can be applied to seeds, plants or fruits of plants or soil where plants grow or soil suitable for plant growth.

In another aspect, the present invention also provides a method for preventing or controlling pests and their larvae and eggs, by applying the pesticidal composition of the present invention to a target useful plant, a target pest or a propagation material of an environment thereof, a target useful plant. The plant propagation material is a seedling, rootstock, nursery seedling, cutting or seed.

A method of preventing or controlling pests and their larvae and eggs by applying the pesticidal composition of the present invention to seeds, to a target useful plant or to soil in which the plant is growing or to soil suitable for plant growth.

A method of preventing or controlling pests and their larvae and eggs by applying the pesticidal composition of the present invention to soil before, after or before or after germination of seeds and/or directly to soil in contact with plant roots or soil suitable for plant growth.

A method of protecting seeds comprising contacting the seeds prior to sowing and/or after germination with a pesticidally effective amount of a pesticidal composition of the present invention.

The plant includes stem and leaf of plant, flower of plant, fruit of plant, etc.

The seed is selected from potato, sunflower, coffee, tobacco, canola, rape, beet, tomato, cucumber, kidney bean, brassica plant, onion, soybean, wheat, barley, rye, oat, sorghum, peanut, sugarcane, rice, broccoli, cabbage, cowpea, carrot, cotton, and corn seed.

A method of preventing or controlling pests comprising the separate, sequential or simultaneous application of a compound of formula I, compound II.

The pesticidal compositions of the present invention may be applied in any desired manner, such as seed coating, soil drenching and/or direct furrow application and/or foliar spray application, as well as pre-, post-, or pre-and post-emergence application.

The present invention provides an insecticidal composition comprising a compound of formula I and a compound II as active ingredients which addresses at least one of the problems of improving biological properties, providing synergistic properties, reducing dosage rates, expanding the spectrum of activity, combining knockdown activity with long-acting action, and resistance management to delay resistance.

The combination of a compound of formula I with a compound II is effective in preventing or controlling animal pests and their larvae and eggs. The simultaneous (i.e., combined or separate) application of the active compounds of formula I and compound II or the sequential application of the compounds of formula I and compound II gives enhanced pest control effects compared to the possible control rates of the individual compounds, which unexpected effects are truly synergistic effects, not just additive effects of activity.

Detailed Description

To facilitate understanding of the present invention, examples are set forth below. It will be apparent to those skilled in the art that the examples are merely to aid in understanding the invention and are not to be construed as a specific limitation thereof.

The invention discovers that: the combination of the compounds of formula I and compound II is effective in preventing or controlling pests and their larvae and eggs. Surprisingly, the pesticidal compositions of the present invention have much higher activity in controlling pests than the sum of the properties of the active compounds alone. This unexpected effect is a true synergistic effect, not just the addition of the activities.

The term "synergistic" as used herein means that the insecticidal effect of the active compound combination or composition of the invention is greater than the sum of the effects of the individual active compounds, or that the effect is superadditive.

The invention provides an insecticidal composition which contains an active compound of a formula I and a compound II, wherein the compound II is selected from one of the following compounds: trifluoro-benzene pyrimidine, thiocyclam, hydrazine-inhibiting and bromarone-fluorobenzene bisamide.

The insecticidal composition disclosed by the invention contains a compound shown in a formula I and trifluoro-phenylpyrimidine.

The insecticidal composition provided by the invention contains a compound shown in a formula I and thiocyclam.

The insecticidal composition disclosed by the invention contains a compound shown in a formula I and antifeedant hydrazine.

The insecticidal composition disclosed by the invention contains a compound shown in a formula I and bromoxynil.

The weight ratio of the compound of formula I to the compound II is 50:1 to 1:300, preferably 25:1 to 1:200, preferably 10:1 to 1:150, more preferably 10:1 to 1:100, more preferably 10:1 to 1:50.

The weight ratio of the compound of formula I and compound II according to the invention may also be, for example, 50:1, 40:1, 30:1, 20:1, 10:1, 5:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:13, 1:15, 1:18, 1:20, 1:25, 1:28, 1:30, 1:35, 1:40, 1:45, 1:50, 1:55, 1:60, 1:65, 1:70, 1:75, 1:80, 1:85, 1:90, 1:95, 1:100, 1:120, 1:150, 1:160, 1:180, 1:200, 1:220, 1:250, 1:280, 1:300.

The more preferred specific composition is formulated as follows:

in the insecticidal composition, when the compound II is selected from trifluoro-phenylpyrimidine, the ratio of the compound of the formula I to the compound II is preferably 15:1-1:15; more preferably 10:1 to 1:10, and still more preferably 5:1 to 1:5.

In the insecticidal composition, when the compound II is selected from the thiocyclam, the ratio of the compound of the formula I to the compound II is preferably 10:1-1:50; more preferably 5:1 to 1:40, still more preferably 1:1 to 1:30, still more preferably 1:1 to 1:25.

In the insecticidal composition, when the compound II is selected from the hydrazine, the ratio of the compound of the formula I to the compound II is preferably 5:1-1:100; more preferably 1:1 to 1:50, still more preferably 1:1 to 1:25, still more preferably 1:1 to 1:10.

In the insecticidal composition, when the compound II is selected from bromoxynil, the ratio of the compound I to the compound II is preferably 15:1-1:15; more preferably 10:1 to 1:10, and still more preferably 5:1 to 1:5.

The preparation of compound II and its action on pests is known. Is disclosed in the website httpp:// www.alanwood.net/peticides.

The total amount of active ingredient in the insecticidal compositions of the present invention may be selected according to specific factors to achieve the desired effect. Such as dosage form, subject to be administered, method of administration, etc.

The invention provides an insecticidal composition which contains active compounds of formula I and compound II, wherein the total weight of the compounds of formula I and the compound II accounts for 1% -90%, preferably 5% -80%, more preferably 5% -70%, still more preferably 5% -60%, and more preferably 5% -50% of the weight of the composition.

An insecticidal composition comprising the active ingredients of formula I and compound II, the weight of the compounds of formula I and compound II together being 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90% by weight of the insecticidal composition.

The insecticidal compositions of the present invention may optionally comprise an auxiliary ingredient such as an agronomically acceptable surfactant and/or filler. Preferably, the auxiliary ingredient is one or a mixture of dispersing agent, wetting agent, antifreeze agent, thickening agent, defoamer, disintegrant, binder and auxiliary carrier.

According to the present invention, the term "filler" refers to a natural or synthetic organic or inorganic compound that can be combined or associated with an active compound to make it easier to apply to a subject (e.g., plants, crops or grasses). Thus, the filler is preferably inert, at least should be agronomically acceptable. The filler may be solid or liquid.

The inactive filler that may be used in the present invention may be either solid or liquid.

Examples of solid fillers that can be used include: plant material powders (e.g., soybean powder, starch, grain powder, wood powder, bark powder, sawdust, walnut shell powder, bran, cellulose powder, coconut shells, corn cob and tobacco stem particles, residues after extraction of plant essence, etc.), clays (e.g., kaolin, bentonite, acidic porcelain clay, etc.), talc, silicas (e.g., diatomaceous earth, silica sand, mica, hydrous silicic acid, calcium silicate), activated carbon, natural minerals (pumice, attapulgite, zeolite, etc.), and burned diatomaceous earth.

As the liquid filler, there may be used, for example, water, isopropyl alcohol, butanol, ethylene glycol, propylene glycol, ethyl acetate, methyl oleate, amides, lactams such as N-methylpyrrolidone, dimethyl sulfoxide, minerals, vegetable oils, etc.

Surfactants which can be used for emulsifying, dispersing, solubilizing and/or wetting the active ingredient compounds include, for example, fatty alcohol polyoxyethylene ethers, polyoxyethylene alkylaryl ethers, polyoxyethylene higher fatty acid esters, phosphoric acid esters of polyoxyethylene alcohols or phenols, fatty acid esters of polyhydric alcohols, naphthalene sulfonic acid polymers, lignin sulfonates, branched copolymers of high molecular combs, butylnaphthalene sulfonates, alkylaryl sulfonates, sodium alkylsulfosuccinates, oils and fats, condensates of fatty alcohols with ethylene oxide, polyacrylates of alkyl taurates, protein hydrolysates, suitable oligosaccharides or polymers, for example based on ethylene monomers, acrylic acid, polyoxyethylene and/or polyoxypropylene alone or in combination with, for example, (poly) alcohols or (poly) amines.

For dispersing, stabilizing and adhering the active ingredient compound, adjuvants such as xanthan gum, magnesium aluminum silicate, gelatin, starch, cellulose methyl ether, polyvinyl alcohol, polyvinyl acetate and natural phospholipids (e.g., cephalin and lecithin), synthetic phospholipids, bentonite, sodium lignin sulfonate and the like can be used.

Wherein the antifreezing agent can be selected from ethylene glycol, propylene glycol, glycerol, and sorbitol. As deflocculant for suspended products, adjuvants such as naphthalene sulfonic acid polymers, polymeric phosphates, and the like can be used. As the defoaming agent, a silicone defoaming agent can be used. For improving the flowability of the solid product, adjuvants such as paraffin, stearate, alkyl phosphate and the like can be used.

Colorants that may be used, for example, inorganic pigments such as iron oxide, titanium oxide, and Prussian blue; and organic pigments/dyes such as alizarin dyes, azo dyes and metal phthalocyanine dyes; and trace elements such as iron, manganese, boron, copper, cobalt, molybdenum and zinc salts.

Optionally, other additional components may also be included, such as protective colloids, binders, thickeners, thixotropic agents, penetrating agents, stabilizers, masking agents.

The pesticidal composition according to the present invention may be used as such or in the form of its formulation or use form prepared therefrom according to its respective physical and/or chemical properties, for example, aerosols, microcapsule suspensions, cold fogging agents, hot fogging agents, microcapsule granules, fine granules, suspension for seed treatment, ready-to-use solutions, powders, emulsifiable concentrates, oil-in-water emulsions, water-in-oil emulsions, macrogranules, microparticles, oil-dispersible powders, oil suspensions, oils, foams, pastes, seed coating agents, colloidal suspensions, suspension emulsions, aqueous solvents, suspending agents, wettable powders, soluble powders, powders and granules, water-soluble granules or tablets, water-soluble powders for seed treatment, wettable powders, natural products and synthetic substances impregnated with active ingredients, microcapsules in polymeric materials and seed-coated substances, and ultra-low volume cold fogging agents and hot fogging agents.

The preferred dosage forms of the insecticidal composition are emulsifiable concentrates, water suspending agents, oil suspending agents, seed treatment dry powder agents, seed treatment suspending agents, water dispersible granules, wettable powder agents, suspending agents, aerosol agents, coated granules, extruded granules, aqueous emulsion, microcapsule suspending agents, dry suspending agents, ultra-low volume liquid agents, electrostatic oil agents, gels, granules and microparticles.

The insecticidal compositions of the present invention may also be applied in combination with other active ingredients such as fungicides, bactericides, attractants, insecticides, acaricides, nematicides, growth regulators, herbicides, safeners, fertilizers or semiochemicals and the like.

The formulations according to the invention can be prepared by mixing the active ingredient with conventional additives in a known manner. Such as conventional extenders and solvents or diluents, emulsifiers, dispersants, and/or binders or fixatives, wetting agents, waterproofing agents, and if desired, siccatives and colorants, stabilizers, pigments, defoamers, preservatives, thickeners, water, and other processing aids.

The pesticidal composition of the present invention includes not only a concentrated commercial composition which is immediately applicable to a subject to be treated by means of a suitable apparatus such as a spraying or powdering apparatus, but also a concentrated commercial composition which is required to be diluted before application to the subject.

The insecticidal compositions of the present invention may be formulated for administration as a combination of the active ingredient compounds thereof, or as a combination of commercial preparations at appropriate dosages thereof.

The insecticidal composition of the invention has good plant compatibility and favorable isothermal animal toxicity, and is suitable for controlling harmful organisms encountered in agriculture, forestry, protection of stored products and materials and hygiene fields, in particular, the classes of the insects (Innecta), arachnida and Nematoda (Nematoda). They are active against species that are generally sensitive and resistant, and active against all or a single developmental stage, and also achieve the surprising "synergistic" effect of preventing or controlling pests.

The invention also provides a use of the insecticidal composition of the invention for preventing or controlling pests. The term "pest" is used herein to mean any organism that can cause a loss of the normal state of a plant. Including the insect pest class (instrecta), arachnida (Arachnida), nematoda (Nematoda).

The class of insects includes lepidoptera, coleoptera, diptera, hemiptera, homoptera, hymenoptera, thysanoptera, isopoda, polyploid, cheilopoda, syndromism, thysanoptera, pachyrhizus, pinaster, orthoptera, blattaria, leather ptera, isoptera, louse.

Lepidopteran pests: borer families (Pyralidae) such as chilo suppressalis (chilosuppressalis (walker), chilo suppressalis (Tryporyzaincertulas (walker)), cnaphalocrocis medinalis (cnaphalocrocis medinalis), cnaphalocrocis medinalis (hellullaundalis), and carpopodium borer (condogethespactionreference); pinaceae (Pieridae) such as Pincerlike Pinceros rapae, papilio citrifolia, papilio tepa; plutella xylostella (Arctidae) such as fall webworm (Hyphantricacuceae); noctidae (notuisae) such as trichoplusia ni (trichoplusia ni), cabbage looper (mamestraabrasica), beet armyworm (spodoptera exigua), prodenia litura (spodoptera litura), cotton bollworm (helicoverpa armigera), armyworm (Pseudaletia separate), agrotis yperlens (agrotis psilon); the family Torilidae (Torilidae) such as leaf roller (adolophysiovoranafava), armeniaca (armeniaca), and leaf roller (homonanamannia); plutellidae (Plutellidae) such as Plutellia xylostella (Plutellia xylostella); gelechidae (Gelechiidae) such as Pink bollworm (pecnnophora gossypiella), red bollworm (Pink bollworm);

Coleopteran pests, such as: rice weevil (sitophilus oryzae elines), citrus leaf beetles (Podagriclomeretricollis Ches), corn weevil (S.zeamails), rice weevil (S.granagarius), ape beetle (Cabbageleaf beetle), ape beetle (Daikon leaf beele), flea beetle (flea beetle), grape flea beetle (Alylactihalybia), curved strip beetle (phyllotreta striolata), cucumber flea beetle (Epitixcucurides), tobacco flea beetle (Ehirtiprennis), eggplant beetle (E.fulmula) yellow gecko (Aulacophoraindica (Gemlin)), leaf beetle (phaedonocochleariae), rice weevil (Lissorhoptrus oryzophilus), callosobruchuys chienensis, yellow meal worm (Tenebrio molitor), corn root beetle (Diabrotica virgifera virgifera), cucumber beetle (Diabrotica undecimpunctata howardi), tortoise (Anomala cuprea), red copper beetle (Anomala rufocuprea), yellow stripe beetle (Phyllotreta striolata), yellow gecko (Aulacophora femoralis), potato beetle (Leptinotarsa decemlineata), rice beetle (eulema oryzae), bostrychidae and longicoidae (Cerambycidae); the method comprises the steps of carrying out a first treatment on the surface of the;

diptera (Diptera), for example, aedes sp, anopheles sp, garden Mao Wen (bishop), red head fly Calliphora erythrocephala, medfly Ceratitis capitata, chrysomyia sp, trypanosoma sp, rickettsia sp, tskin Cordylobia anthropophaga, culex sp, huang Ying (Cuterebra sp), olive fly Dermatobia hominis, drosophila sp, fasciaria sp, gastralgia sp black flies (hylemia spp.), dermatophagoides (Hypoderma spp.), liriomyza spp.), green flies (Lucilia spp.), house flies (Musca spp.), green stinkbug (Nezara spp.), crazy flies (Oestrus spp.), swedish wheat straw flies (oscilla frat), chenopodium quinoa (Pegomyia hyoscyami), tsetse flies (Phorbia spp.), stinking flies (stoloxys spp), tabanus spp, tannia spp, european mosquitoes (Tipula paludosa), and dirty flies.

Heteroptera (Heteroptera), e.g., cucurbita moschata (Anasa triss), apostigma (Anestiposide sp.), apostigma (Blissus sp.), apostigma (Calocoris sp.), campylomma livida, apostigma (Caloglius sp.), ainsoma (Cimex sp.), creontiades dilutus, apostigma (Dasynus pirus), dichelops furcatus, apostigma (Diconocoris hewetti), apostigma (Dysosiphon sp.), apostigma (Euschslus sp.), aleurosptus (Euschstus sp.), flat stingus (Euygaster sp.), helicope sp, horcias nobilellus, apostigma (Leptosporidium sp.), bloophorus (Leptoglossus phyllopus), apostigma (Lygus sp.), apostigma (Phosphus sp.), pigus (Pigus sp.), pigskin (Piporus sp.), pigskin (26, pigskin sp), pigskin (Pitus sp.), pigskin (Pigskin sp), pistacia sp (Pigskin), pistacia sp (Pistacia sp).

Homoptera (Homoptera), for example, the species of Alternaria (Acyrthosipopon spp.), aenolamia spp., long Maimu, aleurothrix spp, eriopsis (Aleurolobus barodensis), aleurothrix spp, cerbera (Amrasca spp.), anura carpdui, kidnerella (Aoniella spp.), soviet Huang Fenya (Aphanostigma piri), aphis (Aphis spp), grape leafhopper (Arboridia apicalis), ericerus (Aspidella spp.), atanelus spp, solanum, australian (Australian) Pneum, bemisia spp.), li Duanwei aphid (Brachycaudus helichrysii), braycspep, brassica oleracea, brown (Brevicoryne brassicae), philis (Huang Tou), philis (Carneocephala fulgida) and Philis (3856). Sugarcane powder horn aphid (Ceratovacuna lanigera), cicada (Ceripoidae), ericerus spp, fragaria (Chaetosiphon fragaefolii), yellow snow white scale (Chionaspis tegalensis), tea leafhopper (Chloriti onukii), juglans mandshurica (Chromaphis juglandicola), phascopea jecorina (Chrysomphalus ficus), corn leafhopper (cicdulina mbila), coccomytilus halli, soft scale genus (Coccus spp), black currant saphenous aphid (Cryptomyzus ribis), dalbulus spp, dialeurodes spp, diaphora spp, white back scale spp, doralis spp, trimerella sp, drosaccha sp), sichup (Dysphis spp), gracilaria sp, easter sp (Easter spp), easter spp The species of the genus Aphis (Eriosoma spp.), erythroneura spp., euscelis bilobatus, gecko (Geococcus coffeae), pseudopeach virus leafhopper (Homalodis cacoagulata), myzus persicae (Hyalopterus arundinis), ericerus (Icerya spp.), pacifica (Idiocerus spp.), bifida (Idioscus spp.), latifolia (Laodelphax striatellus), lecanium spp, lepidium spp (Lepidospora spp.), aphis (Lipaposa spp.), aphis Raphani (Lipaphia cersimi), aliphus (Macrosium p.), mahanarva fimbriolata, aphis sorghum (Melanaphis sacchari), metcalfilla spp.), myzus spp, myzus aphis (Metopolophium dirhodum), myzus plague (Monellia costalis), myzus spp), lactuca sativa (Nasonovia ribisnigri), hedycepa spp (Nepeta spp), nepalum spp (Nepsidium spp.), and Nepalum spp. Yang Meiyuan Bemisia (Parabemisia myricae), pelargonium (Parlatifolia spp.), pemphrena (Pemphigus spp.), corn wax hopper (Peregrinus maidis), ericactus (Phenacoccus spp.), yang Pingchi Aphis (Phloeomyzus passerinii), phyllosperma negundo (Phorodon humuli), vitis (Phylloxa spp.), su Tiehe point and Scleroder (Pinnaspis aspidistrae), pelargonium (Planococcus spp.), pyrus pyriformis (Protopulvinaria pyriformis), sang Baidun (Pseudaulacaspis pentagona), lepidium (Pseudomonas spp.), phyllostachys (Psyloma spp.), lepidium (Pterocephalus spp.), pyzella spp., ericerus (Quadras spp.), gastrodia, quickia spp. Sp., lepidium (Quickii spp.), gecko spp. Sp., quickii spp. The genus Sinonotus (Rhopaliosphum spp.), gecko (Saissetia spp.), scaphoides titanus, mylabris (Schizaphis graminum), su Tieci round-spotted Gecko (Selenaspidus articulatus), alGastrodia spinosa (Sogata spp.), bai Beifei lice (Sogatella furcifera), brown planthoppers (Nilaparvata lugens), tomapsis spp.), aphis (Toxoptera spp.), bemisia (Trialeurodes vaporariorum), phyllostachys (Trioza spp.), leafhopper (Typhlocba spp.), petanus acuta (Una spp.), and Vitex vinifera (Viteus viniferi).

Hymenoptera (Hymenoptera), for example, genus pine (Diprion spp.), genus hornet (holocompap spp.), genus Mao Yi (Lasius spp.), genus tergite (Monomorium pharaonis), genus wasp (Vespa spp.).

Orthoptera (Orthoptera), e.g., family cricket (Acheta domesticus), oriental cockroach (Blatta orientalis), german cockroach (Blattella germanica), mole cricket (grylotalpa spp.), madverruca (Leucophaea maderae), migratory locust (Locusta spp.), black locust (Melanoplus spp.), american cockroach (Periplaneta americana), desert locust (Schistocerca gregaria), sword locust (Acrididae); stinkbug (megacappa infestans), plant bug (eurydemarkugosus), plant bug (eircororislewisi), bai Xingchun (eircororisparvus), green plant bug (nezaraviridula), plant bug (plautialstali), harlequin bug (halymorphamista), plant bug (clestumpager), chinese stinkbug (leptosphakochia), azalea stinkbug (azaleas), stinkbug (stephantispyri), and brown plant bug (trigonotyrososci estiferum).

Thysanoptera (Thysanoptera), for example, rice Thrips (Baliothrips biformis), enneothrips flavens, frankliniella spp.), nethrips (Heliothrips spp.), greenhouse Thrips (Hercinothrips femoralis), kakothrips (kakothorps spp.), grape Thrips (Rhipiphorothrips cruentatus), hard Thrips (scirtthorps spp.), taeniothrips cardamoni, thrips (threps spp).

Isoptera (Isoptera), e.g., the genus rottermes (retiulitermes spp.), the genus Odontotermes (odotottermes spp.).

The order Thysanoura, for example, thysanora (Lepisma saccharina).

The order of the lice (Anoplura, phthiaapetera), for example, the genus Pediculus (Damalinia spp.), the genus Pediculus (Haematopinus spp.), the genus Pediculus (Linognathus spp.), the genus Pediculus (Trichodectes spp.).

The Arachnida (Arachnida) are pests of the order acarina. Such as Tetranychus fulgidus (pannchus citri), tetranychus cinnabarinus (Tetranychus tenuis), tetranychus urticae (Tetranychus fulgidus), tetranychus urticae (Tetranychus urticae), tetranychus urticae (Tetranychus), tetranychus urticae (Orthosiphon), tetranychus fulgidus (Ruta), tetranychus cinnabarinus (Ruta), tetranychus rubrum (Ruta) or Puccinium, alternaria (Legiocephalus), tetranychus (Legiopus) or Puccinium, legiocephalus (Legiocephalus), legiocephalus sanguineus (Legiocephalus), legiocephalus gracilis (Phatatus), legiocephalus gracilis (Rhagogicus), leptodermatum (Legiocephalus), leptodermatum (Russian) or Puccinium (Legionella), legionella (Legionella) and the like, and the genus Phlebophus (Legionella).

Bivalve class, e.g., borrelia (Dreissena spp.).

The order Chilopoda (Chilopoda), for example, the genus Geophilus (Geophilus spp.), scutigera spp.

The order of the tail of the bullet (Collembola), for example, the army acanthus (Onychiurus armatus).

The order Dermaptera (Dermaptera), for example, forficula auricularia (Forficula auricularia).

The order of the bipeda (biplopoda), for example Blaniulus guttulatus.

Gastropoda (gastopoda), for example, aron spp., binomphalia spp., brina spp., wild slug spp, delphina spp, galba spp, samara spp, oncomelania spp, and succiniro spp.

Isopoda (Isopoda), for example, armadillidium (Armadillidium vulgare), chlamydia (Oniscus aselus), armadillidium (Porcellio scaber).

Siphonaptera (Siphonaptera), for example, metridia (Ceratophyllus spp.), porphyra (Xenopsylla cheopis).

Synthetic orders (symphysa), e.g., white pine worms (Scutigerella immaculata).

Representative organisms of the class Nematoda are selected from the group consisting of Meloidogyne (Meloidogyne spp.), heterodera (Heterodera spp.), heterodera (Globodera spp.), radopholus (radophossuspp.), pratophagous nematode (Pratylenchus spp.), long-needle nematode (Longidorus spp.), and the like. Soybean cyst nematodes (hetodera), golden-point nematodes (golcoderarostochiensis), meloidogyne incognita (meloidogyne incognita) and the like are preferred.

In particular, the insecticidal compositions of the present invention exhibit an surprising "synergistic" effect against or in controlling insects of the family borer, plutellaceae, noctuid, leaf beetle, plant hopper, aphid, leaf beetle and larvae and eggs thereof.

Borer families (Pyralidae) such as chilo suppressalis (chilosuppressalis (walker), chilo suppressalis (Tryporyzaincertulas (walker)), cnaphalocrocis medinalis (guenee), cabbage borer (hellullaundalis), and carpopodium borer (condonetspeciferlis);

noctidae (notuisae) such as noctuid (trichoplusia ni), cabbage looper (mamestraabrasica), beet armyworm (spodoptera exigua), prodenia litura (spodoptera litura), cotton bollworm (helicoverpa armigera), oriental armyworm (Pseudaletia separate), agrotis yperlon (Agrotis ipsilon);

plutellidae (Plutellidae) such as Plutellia xylostella (Plutellia xylostella);

aphididae family: such as Myzus persicae (Myzus persicae), cotton aphid (Aphis gossypii), cabbage aphid (Brevicoryne brassicae), green tea cryptotaenia frontal aphid (Cryptomyzus ribis), broad bean aphid (Aphis fabae), apple aphid (Aphis), apple cotton aphid (Eriosoma lanigerum), peach tail aphid (hyalopecurarunddinis), grape root nodule aphid (Phylloxera vastatrix), wheat long tube aphid (Macrosiphum avenae), wheat long tube aphid (Macrosiphum avenae), wheat no net long tube aphid (Metopolophium dirhodum), wheat Gu Yiguan aphid (Rhopalosiphum padi), wheat binary aphid (Schizaphis graminum);

The family of plant hoppers: laodelphax striatellus (Laodelphax striatellus), brown planthopper (Nilaparvata lugens stal), brown planthopper (Sogatella furcifera), and sugar cane planthopper (Perkinsiella saccharicidactylaldy);

leaf beetle family: yellow flea beetle (Phyllotreta striolata), yellow melon (Aulacophora femoralis), great ape beetle (cabageleaf beetle), and ape beetle (Daikon leaf beele);

leaf of the family Tetranychidae: panonychus citri (panochuscitrile), tetranychus cinnabarinus (Tetranychus cinnabarinus), panonychus ulmi (panochamus mali), tetranychus urticae (tetranychus urticae), tetranychus hawkthorn (tetranychus viennensis), tetranychus citri (eotetanides tskanmitis), tetranychus aestivus (acerba).

More particularly, the insecticidal composition of the present invention is particularly effective for preventing or controlling pests such as myzus persicae, cotton aphid, peach aphid, plutella xylostella, asparagus caterpillar, spodoptera frugiperda, cotton bollworm, chilo suppressalis, cnaphalocrocis medinalis, phyllotreta striolata, great ape leaf beetle, small ape leaf beetle, leaf scald mite, citrus panonychus, and tetranychus cinnabarinus, as well as larvae and eggs thereof.

The insecticidal composition of the invention surprisingly exhibits extremely high activity in the treatment of plants, plant propagation material, plant growth soil for the prevention or control of pests of the family borer, plutellaceae, noctuidae, phyllotoferae, delphacidae, aphididae, tetranychidae and their larvae and eggs.

The insecticidal composition of the invention has excellent control efficacy on insects of the family of borer, the family of plutellaceae, the family of noctuidae, the family of leaf beetles, the family of plant hoppers, the family of aphids, the family of leaf beetles and their larvae and eggs at low doses.

In another aspect, the invention also provides the use of an insecticidal composition for preventing or controlling insects of the family borer, the family plutellaceae, the family noctuidae, the family phyllotoferae, the family delphadae, the family aphidae, the family tetranychidae and their larvae and eggs.

The invention provides an insecticidal composition for preventing or controlling myzus persicae, cotton aphid, peach aphid, plutella xylostella, asparagus caterpillar, spodoptera frugiperda, cotton bollworm, chilo suppressalis, cnaphalocrocis medinalis, phyllotreta striolata, great ape leaf, small ape leaf worm, two leaf spot mite pests and larvae and eggs thereof.

The pesticidal composition of the present invention may be applied to any and all stages of development of pests, such as eggs, larvae, pupae and adults. Pests can be controlled by contacting the target pest, its food supply, habitat, breeding grounds or its locus with a pesticidally effective amount of the pesticidal composition of the present invention.

"locus" refers to a plant, plant propagation material, soil, area, material or environment in which pests are growing or are likely to grow.

"pesticidally effective amount" means the amount of the pesticidal composition of the present invention required to obtain an observable effect on growth, including death, prevention or removal effects, destructive effects or effects of reducing the appearance and activity of animal pests. The pesticidally effective amounts of the various pesticidal compositions used in the present invention may vary. The pesticidally effective amount of the composition will also vary depending upon the prevailing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, etc.

According to the invention, all plants and parts of plants can be treated. "plants" are understood here to mean all plants and plant populations such as desired and undesired wild plants or crops (including naturally occurring crops). The crop may be plants obtained by conventional breeding and optimization methods, or by biotechnological and genetic engineering methods or by combinations of these methods, including transgenic plants and plant cultivars including those which may or may not be protected by plant breeder certificates. Plant parts are understood to mean all above-and below-ground parts and plant organs such as seedlings, leaves, flowers and roots, examples which may be mentioned being leaves, needles, stems, flowers, fruit bodies, fruits and seeds and roots, tubers and rhizomes. Parts of plants also include post-harvest plants and vegetative and generative propagation material, such as seedlings, tubers, rhizomes, cuttings and seeds.

As described above, all plants and parts thereof can be treated according to the present invention. In a preferred embodiment, wild plant varieties and plant cultivars, or those obtained by conventional biological breeding methods such as crossing or protoplast fusion, and parts thereof, are treated. In a more preferred embodiment, transgenic plants and plant cultivars obtained by genetic engineering (optionally in combination with conventional methods (Genetically Modified Organisms) and parts thereof) are treated.

The insecticidal composition has good plant compatibility, and is suitable for controlling pests, especially insects, mites and nematodes, fungi, rodents, microorganisms and the like, especially the pests of the family of borer, plutellaceae, noctuid, phyllotoferae, delphadae, aphididae and tetranychidae. It is preferably applicable to foliar treatment, soil treatment and seed treatment.

In another aspect, the present invention also provides a method for preventing or controlling pests and their larvae and eggs, by applying the pesticidal composition of the present invention to a target useful plant, a target pest or a propagation material of an environment thereof, a target useful plant. It can be carried out before and after the plants, plant propagation material or the environment are infested with pests.

The term "plant propagation material" is understood to mean all plant parts, such as seeds, which are capable of reproductive capacity and which can be used for reproducing the latter, as well as plant materials such as cuttings or tubers (e.g. potatoes). Thus, plant parts as used herein include plant propagation material. Mention may be made, for example, of seeds, roots, fruits, tubers, bulbs, rhizomes and plant parts. Germinated plants to be germinated from soil or suppressed after emergence of seedlings, and effective plants. Young plants may be protected by impregnation, either entirely or partially, prior to implantation.

The plant propagation material is a seedling, rootstock, nursery seedling, cutting or seed. Seeds are preferred.

The insecticidal composition of the present invention can be applied to seeds, plants or fruits of plants or soil where plants grow or soil suitable for plant growth.

A method of protecting seeds comprising contacting the seeds prior to sowing and/or after germination with a pesticidally effective amount of a pesticidal composition of the present invention.

The seed is selected from potato, sunflower, coffee, tobacco, canola, rape, beet, tomato, cucumber, kidney bean, brassica plant, onion, soybean, wheat, barley, rye, oat, sorghum, peanut, sugarcane, rice, broccoli, cabbage, cowpea, carrot, cotton, and corn seed. Of particular importance are the treatment of seeds of wheat, barley, rye, oats, maize, cotton, canola, rape and rice.

Accordingly, the present invention provides a method of protecting seeds, seedling roots and shoots from attack by soil and foliar insects comprising contacting the seeds with an effective amount of the insecticidal composition of the present invention prior to sowing and/or after pregermination.

The present invention also provides a method for controlling or preventing pests and their larvae and eggs in plant propagation material and plant organs, plant parts and/or plants grown thereafter, comprising applying the pesticidal composition of the present invention to the plant propagation material or its environment. The plant propagation material is preferably seeds.

Most damage to crop plants caused by pests occurs as early as the seeds, during storage and after the seeds are sown into the soil and during or after germination of the plants, when they are infested. This stage is particularly critical because the roots and shoots of the growing plant are particularly sensitive and even minor damage can lead to death of the whole plant. Thus, protection of seeds and germinated plants by the use of suitable compositions is of particular interest.

The invention also relates in particular to a method for protecting seeds and germinating plants from pests and their larvae and eggs by treating the seeds with the insecticidal composition according to the invention. The method of the present invention for protecting seeds and germinated plants from attack by insects of the family boredae, plutellaceae, noctuidaceae, phyllotoferae, delphadae, aphidae, phyllotoidae and their larvae and eggs comprises a method of simultaneously treating the seeds with a compound of formula I and a compound II. It also includes a method of treating the seed with a compound of formula I and a compound II at different times.

A method for preventing or controlling pests and their larvae and eggs, which comprises treating the seeds from which plants are expected to grow with a synergistically effective amount of the pesticidal composition of the present invention before sowing and/or after germination.

The invention also relates to the use of the insecticidal composition according to the invention for treating seeds to protect said seeds and plants growing therefrom from attack by pests and their larvae and eggs.

Furthermore, the present invention relates to seeds treated with the pesticidal composition of the present invention to obtain protection from pests and their larvae and eggs.

The invention also relates to seeds treated simultaneously with the compound of formula I and the compound II. The invention also relates to seeds treated with a compound of formula I and a compound II at different times. For seeds treated with the compound of formula I and compound II at different times, the individual active compounds of the insecticidal compositions of the present invention may be present in different layers on the seed. Wherein the layers comprising the compound of formula I and the compound II may optionally be separated by an intermediate layer. The invention also relates to seeds in which the compounds of formula I and the compounds II are applied as coating components or as one or more additional layers outside the coating.

The pesticidal composition of the present invention may be applied to seeds of any physiological state. Preferably the seeds are in a sufficiently durable state so as not to be damaged during the treatment process. In general, the seed may be seed harvested from the field, removed from the plant, isolated from any cobs, stems, husks and surrounding pulp or other non-seed plant material. The seed may also preferably be biologically stable to the extent that the treatment does not cause biological damage to the seed. The application to the seeds may be treated at any time between seed harvest and seed sowing or during the sowing process. The seeds may also be germinated before or after treatment.

Seeds treated with the insecticidal composition of the present invention can be stored, managed, sown and cultivated.

Seed treatment can be accomplished by applying the compound of formula I and compound II thereto in any desired order or simultaneously.

Seed treatment occurs on unsown seeds, the term "unsown seeds" is intended to include seeds that are sown in the ground for any period between the time of seed harvest and the time of seed germination and growth of the plant. Preferably, the treatment occurs before sowing the seeds, whereby the sowing seeds have been pre-treated with the combination. In particular, seed coating or seed pelleting is preferred in the treatment of the combination of the invention. After treatment, the components of each combination adhere to the seed and are therefore useful for pest control.

Seed treatment methods include all methods known to those skilled in the art as suitable for treating seeds, such as seed dressing, seed coating, seed soaking, seed coating, seed multilayer coating, seed soaking, seed dusting, and seed pelleting.

Seeds treated with the insecticidal compositions of the present invention provide protection from insect pests not only for the seeds themselves but also for plants growing from the seeds after their emergence. Thus, it may not be necessary to treat the plants directly at or shortly after sowing.

The composition of the present invention may be applied to seeds, plants or fruits of plants or soil where plants are grown or soil suitable for plant growth.

The present invention also provides a method for preventing or controlling pests and their larvae and eggs, comprising applying the pesticidal composition of the present invention to seeds, to a target useful plant or to soil in which plants are grown or to soil suitable for plant growth.

In another aspect, the present invention also provides a method for preventing or controlling pests and their larvae and eggs by applying the pesticidal composition of the present invention to soil before, after or before or after germination of seeds and/or directly to soil in contact with plant roots or soil suitable for plant growth.

The present invention also provides a method of protecting plants from attack by pests and their larvae and eggs, comprising applying the pesticidal composition of the present invention to the environment, habitat or storage area in which the useful plants are grown. The environment and habitat of plant growth refer to a support body capable of rooting and growing crops, for example: soil, water, etc., concrete raw materials may be, for example, sand, pumice, vermiculite, diatomaceous earth, agar, gel-like substance, polymer substance, asbestos, wood chips, bark, etc. Soil is preferred.

The invention also provides a method of protecting plants against attack by insects of the family boredae, the family plutellaceae, the family noctuidae, the family phyllotobiaceae, the family delphadae, the family aphanidae, the family phyllotoidae and their larvae and eggs, comprising the combined, separate or sequential application of the active ingredients of the compounds of formula I and of the compounds II. In the case of separate applications, the sequence generally has no influence on the result of the control measures.

A method for preventing or controlling pests and their larvae and eggs comprising the separate, sequential or simultaneous administration of a compound of formula I, compound II.

The present invention also provides a method of protecting a useful plant from attack by pests and their larvae and eggs, which comprises applying a combination comprising a compound of formula I and a compound II, in any desired order or simultaneously, on the target useful plant or its environment, the target pest or its environment, the propagation material of the target useful plant.

The insecticidal compositions of the present invention include not only ready-to-use compositions that can be applied to plants or plant propagation material with a suitable device, but also commercial concentrates that must be diluted with water prior to application.

The insecticidal compositions of the present invention may be applied undiluted or diluted with water.

The present invention provides a method for preventing or controlling pests and their larvae and eggs by applying the pesticidal composition of the present invention to a target useful plant or its environment, to propagation material of the target useful plant, other pesticides being able to be applied simultaneously with or separately from the application of the compounds of formula I and compound II, and in the case of separate application of the compounds of formula I and compound II, each other pesticide being able to be applied simultaneously with, between or after the application of the compounds of formula I and compound II.

Methods of treating target pests, target useful plants, or seeds, soil with the pesticidal composition of the present invention include, for example, spreading treatment, soil treatment, surface treatment, and fumigation treatment. Spreading treatments include, for example, spreading, spraying, atomizing, and particle application. Soil treatment includes, for example, soil irrigation and soil mixing. Surface treatments include, for example, coating and covering. Fumigation treatment includes, for example, covering the soil with polyethylene film after injection into the soil. The preferred direct treatment of plants is foliar application treatment.

The pesticidal composition of the present invention is typically applied by the applicator to a backpack sprayer, spray can, spray aircraft or irrigation system. The insecticidal compositions of the present invention are typically formulated with water, buffers and/or other adjuvants to the desired application concentration to provide a ready-to-use spray.

Compared with the prior art, the invention has at least the following beneficial effects:

(1) The pesticidal composition of the present invention may show synergistic activity compared to the activity of the compound alone;

(2) The insecticidal composition of the present invention treats plants and plant propagation materials to a level that represents a significant improvement;

(3) The pesticidal composition of the present invention reduces infestation and attack by any undesired pests and their larvae and eggs; in particular, the moth, plutellaceae, noctuidae, phyllotoferae, delphadae, aphidae, abaenae pests and their larvae and eggs;

(4) The invention mixes the compound of the formula I and the compound II, solves the problems of lasting effect and quick acting property, thereby reducing the times of medicine application and lowering the labor cost;

(5) The insecticidal composition of the present invention exhibits high efficiency, thus reducing the dosage rate and reducing the load on the environment;

biological test case

The expected effect of a particular combination of two active ingredients can be calculated using the so-called "Colby formula" (see s.r. Colby, "Calculating Synergistic and Antagonistic Responses of HerbicideCombinations", wells 1967,15, 20-22):

x is the control effect when using an active ingredient of the formula I in an amount of m g/ha or at a concentration of m ppm, expressed as a percentage of untreated control,

y is the control effect when using an active ingredient compound II in an amount of n g/ha or at a concentration of n ppm, expressed as a percentage of untreated control,

e is the control effect when using the active ingredients of the formula I and the compound II in amounts of m and n g/ha or at concentrations of m and n ppm, expressed as a percentage of untreated control,

if the actual control effect exceeds the calculated value, the lethal effect of the composition is super-additive, i.e., there is a synergistic effect.

Test example 1 cabbage aphid test

Preparing a liquid medicine: the stock solution of the compound of formula I (synthesized by the method described in WO 2007/144100) and the stock solution of the compound II in Table 1 were each dissolved in acetone to prepare a single preparation, and diluted to the desired concentration with an aqueous solution containing 0.1% Tween-80.

The method is characterized in that the green peach aphid (Myzus persicae Sulzer) is taken as a tested pest, picked from cabbage vegetable fields in Jiangsu Kunshan test lands, and after first-generation breeding is carried out on insect-free cabbages planted in an insect-proof net room, 30 green peach aphids with similar body colors and uniform sizes are selected as a group for indoor test.

Soaking aphid and cabbage leaf in the prepared medicinal liquid for 10 s, taking out, sucking excessive medicinal liquid with absorbent paper, and placing into plastic beaker with diameter of 6cm and height of 10 cm. After the test is finished, the reaction is transferred to 25+/-2 ^o And C, feeding in a constant temperature incubator with the relative humidity of 60-80%. Control treatments a blank was made with the treatment without agent. The test results were checked by the agent treatment for 72 h. If the control mortality rate is greater than 20%, the test is reworked.

The calculation method comprises the following steps:

mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

Table 1 test of combinations of Compounds of formula I and Compound II on the green peach aphid

Test 2 plutella xylostella test

Preparing a liquid medicine: the compound of formula I (synthesized by the method described in WO 2007/144100), the compound II precursor of table 2, were dissolved with acetone to prepare a single stock solution, which was diluted to the desired concentration with an aqueous solution containing 0.1% tween-80.

Plutella xylostella ((Plutella xylostella Linnaeus) Oriental village farm indoor breeding population in Jiangsu Kunshan, 10 heads were used for indoor experiment.

Soaking caulis et folium Brassicae Capitatae in medicinal liquid for 10S, air drying, placing in glass culture dish (diameter of 60 cm) with filter paper, moistening petiole with wet cotton ball, inoculating 3-year old larva into leaf, sealing with preservative film, preserving, covering, and placing in 25+ -1 ^o C, relative humidity 60-80%, illumination period L: d= (16:8) h in an incubator.

Control treatments a blank was made with the treatment without agent. The results were checked after 72 holding in the incubator. The death judgment criteria were: the body is touched by a poking needle, and the body is completely unresponsive or can not normally respond to death.

The calculation method comprises the following steps:

mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

TABLE 2 control of plutella xylostella by combination of Compounds of formula I and Compound II

Test example 3 Chilo suppressalis test

Preparing a liquid medicine: the compound of formula I (synthesized by the method described in WO 2007/144100), the compound II precursor of table 3, were dissolved with acetone to prepare a single stock solution, which was diluted to the desired concentration with an aqueous solution containing 0.1% tween-80.

Chilo suppressalis (Chilo suppessalis). Chilo suppressalis egg masses are collected from Oriental village farm in Kunshan of Jiangsu, and after 2-3 generations of indoor feeding, 2-year middle-period larvae are selected for test.

And taking well-grown rice seedlings, and sucking the surface moisture by using water-absorbing paper. Soaking in the prepared medicinal liquid for about 10 seconds, and naturally drying in shade. Into a test tube. The 2-instar larvae are connected with 10 heads/tube and are plugged by cotton. Placed at 25+ -1 ^o C, the relative humidity is 60% -80%, and the illumination period L is as follows: d= (16:8) h in an incubator. Control treatments a blank was made with the treatment without agent. After 4d the test results were checked. Failure to crawl normally is considered dead worm.

If the control mortality rate is greater than 20%, the test is reworked.

The calculation method comprises the following steps:

mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

TABLE 3 control of Chilo suppressalis by combination of Compounds of formula I and Compound II

Test example 4 Rice leaf roller test

Preparing a liquid medicine: the compound of formula I (synthesized by the method described in WO 2007/144100), the crude drug of compound II in table 4, were dissolved in acetone to prepare a single dose of mother liquor, which was then diluted to the desired concentration with an aqueous solution containing 0.1% tween-80.

The cnaphalocrocis medinalis (Cnaphalocrocis medinalis) line was harvested from eastern village farm in the Jiangsu Kunshan and 3-generation 3-year test insects were bred with seedlings in the house.

Immersing fresh and tender rice seedlings in the liquid medicine to be tested for 10s, taking out, putting into a prepared glass test tube, naturally airing, then inoculating 10 heads of 3-year larva of cnaphalocrocis medinalis in the test tube, fastening a pipe orifice with gauze, and culturing in an observation room after treatment.

Control treatments a blank was made with the treatment without agent. After 72 hours of treatment, the rice stems are peeled off to check the death of the test insects, and the death is recorded. The death judgment standard of the test insects is as follows: gently contact with the test insects with forceps was counted as dead without reaction. If the control mortality rate is greater than 20%, the test is reworked.

The culture conditions of the target to be tested and the target after the test are 25+/-1 ^o C, the relative humidity is 60% -80%, and the illumination period L is as follows: d= (16:8) h incubator.

The calculation method comprises the following steps:

mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

TABLE 4 control of cnaphalocrocis medinalis by combination of Compounds of formula I and Compound II

Test example 5 brown planthopper test of rice

Preparing a liquid medicine: the compound of formula I (synthesized by the method described in WO 2007/144100), the crude drug of compound II in table 5, were dissolved in acetone to prepare a single dose of mother liquor, which was then diluted to the desired concentration with an aqueous solution containing 0.1% tween-80.

Brown planthoppers (Nilaparvata lugens stal) are obtained from the rice test field of the eastern village farm in the Jiangsu Kunshan, and are raised indoors with rice seedlings.

The temperature of the insect-raising room is 28+/-2 ^o And C, the relative humidity is above 70%, and the light is irradiated for 14 hours a day. After the rice seeds are sprouted, sowing the rice seeds in a plastic box with the length of 20cm multiplied by 30cm, and raising the nymphs of the rice planthoppers to adults when the rice seedlings grow to more than 10 cm. Putting the potted rice plants without the rice planthopper eggs into a 30cm multiplied by 50cm insect raising net cage, inoculating female imago with eggs and spawning for 2 to 3 days, taking out rice seedlings, and replacing the rice plants without the insect eggs in the insect raising box. After the brown planthopper eggs on the rice plants taken out of the insect-raising box are hatched, brown planthopper nymphs with the age of 3 days are taken each time for testing.

Selecting rice seedlings cultivated in a greenhouse, digging and cleaning the rice seedlings, cutting rice stems with a few root hairs and a length of about 10cm, and airing the rice stems in a shade until no water mark exists on the surfaces of the rice stems for standby. Soaking the prepared rice stems in the medicinal liquid for 30 seconds, taking out, air drying slightly, and placing into 3cm×20cm test tubes each with 3 rice stems. The test tube was sealed with black cloth and covered with a wet towel for moisture retention.

The insect is transferred into test tubes by a insect suction device, 15 heads of each test tube are covered by gauze at the mouth of each test tube. The treated test insects are placed at a temperature of 25+/-1 DEG C ^o C, the relative humidity is 60% -80%, and the illumination period is L: d= (16:8) h. The test insects were checked for mortality by 48h and recorded. The death judgment standard of the test insects is as follows: gently contact with the test insects with forceps was counted as dead without reaction. If the control mortality rate is greater than 20%, the test is reworked. Control treatments a blank was made with the treatment without agent.

The calculation method comprises the following steps:

mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

TABLE 5 control of brown planthoppers by combinations of Compounds of formula I and Compound II

Test example 6 yellow stripe flea beetle test

Preparing a liquid medicine: the compound of formula I (synthesized by the method described in WO 2007/144100) and the crude drug of compound II in table 6 were each dissolved in acetone to prepare a single-dose mother liquor, which was then diluted to the desired concentration with an aqueous solution containing 0.1% tween-80.

Yellow flea beetle (Phyllotreta striolata) is taken as a test pest from a vegetable field of the eastern village farm in the Jiangsu Kunshan. Before the test, yellow stripe flea beetles are inoculated on greenhouse potted cabbages planted in a laboratory insect-proof net room. And (5) continuously feeding for 72 hours, and selecting yellow flea beetles with consistent sizes for testing. The room test was performed with 20 heads as a group.

Soaking cabbage leaves which are not polluted by the medicament in the liquid medicine to be tested for 15 seconds, taking out, naturally airing, placing in a glass bottle, inoculating 20 yellow leaf-streak beetles with the same size, and sealing by using spun yarn cloth. After the test is finished, the reaction is transferred to 25+/-2 ^o And C, feeding in a constant temperature incubator with the relative humidity of 70-80%. Control treatments a blank was made with a clear water treatment without the agent. The test results were checked by the agent treatment for 48 h. The dead insects are regarded as the light touch and no reaction of the writing brush. If the control mortality rate is greater than 20%, the test is reworked.

The calculation method comprises the following steps:

mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

TABLE 6 test of combinations of Compounds of formula I and Compound II on phyllotreta striolata

The test results in tables 1-6 show that the combination of the compounds of the formula I and the compound II has synergistic effect on the control of cabbage aphids, brown planthoppers, cnaphalocrocis medinalis, chilo suppressalis, plutella xylostella and phyllotreta striolata.

Claims (17)

1. An insecticidal composition comprising the active ingredients of a compound of formula I and a compound II:

compounds of formula I

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The compound II is selected from bromofluorobenzene bisamide, and the weight ratio of the compound I to the compound II is 10:1-1:50.

2. The insecticidal composition according to claim 1 wherein the weight ratio of the compound of formula I to the compound of formula II is from 15:1 to 1:15.

3. The insecticidal composition according to claim 1 wherein the weight ratio of the compound of formula I to the compound of formula II is from 10:1 to 1:10.

4. The insecticidal composition according to claim 1 wherein the weight ratio of the compound of formula I to the compound of formula II is from 5:1 to 1:5.

5. The insecticidal composition of claim 1, further comprising a surfactant and/or a filler.

6. A pesticidal composition according to claim 1, wherein the weight of the compounds of formula I and compound II together comprise from 5% to 80% by weight of the pesticidal composition.

7. A pesticidal composition according to claim 1, wherein the weight of the compounds of formula I and compound II together comprise from 5% to 70% by weight of the pesticidal composition.

8. A pesticidal composition according to claim 1, wherein the weight of the compounds of formula I and compound II together comprise from 5% to 60% by weight of the pesticidal composition.

9. A pesticidal composition according to claim 1, wherein the weight of the compounds of formula I and compound II together comprise from 5% to 50% by weight of the pesticidal composition.

10. The insecticidal composition according to claim 1 in the form of an emulsifiable concentrate, an aqueous suspension, an oil suspension, a seed-treatment dry powder, a seed-treatment suspension, a water dispersible granule, a wettable powder, a suspoemulsion, an aerosol, a coated granule, an extruded granule, an aqueous emulsion, a microcapsule suspension-suspension, a dry suspension, an ultra-low volume liquid, an electrostatic oil, a gel, a granule, a microparticle.

11. Use of the pesticidal composition of claim 1 for preventing or controlling pests and their larvae and eggs.

12. Use of the insecticidal composition of claim 1 for preventing or controlling pests of the family borer, the family plutellaceae, the family noctuidae, the family phyllotoridae, the family planthopper, the family aphidae, the family tetranychidae.

13. Use of the insecticidal composition of claim 1 for the prevention or control of myzus persicae, cotton aphid, peach aphid, plutella xylostella, beet armyworm, spodoptera frugiperda, cotton bollworm, chilo suppressalis, cnaphalocrocis medinalis, phyllotreta striolata, ape leaf worm, leaf scald mite pest, and larvae and eggs thereof.

14. A method for preventing or controlling pests and their larvae and eggs, characterized in that the pesticidal composition according to claim 1 is applied to a target useful plant, a target pest or its environment, propagation material of a target useful plant.

15. A method for preventing or controlling pests and their larvae and eggs, characterized in that the pesticidal composition of claim 1 is applied to seeds of a target useful plant, to a target useful plant or to soil in which plants are grown or to soil suitable for plant growth.

16. A method for preventing or controlling pests and their larvae and eggs, characterized in that the pesticidal composition of claim 1 is applied to the soil before, after or before or after germination of the seed and/or directly to the soil in contact with the plant roots or to the soil suitable for plant growth.

17. A method of protecting seeds, characterized in that the seeds are contacted with a pesticidally effective amount of the pesticidal composition of claim 1 before sowing and/or after germination.