CN116439885B - Multi-segment telescopic intracranial stent - Google Patents

Multi-segment telescopic intracranial stent Download PDF

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Publication number
CN116439885B
CN116439885B CN202310414406.3A CN202310414406A CN116439885B CN 116439885 B CN116439885 B CN 116439885B CN 202310414406 A CN202310414406 A CN 202310414406A CN 116439885 B CN116439885 B CN 116439885B
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China
Prior art keywords
taking assembly
thrombus taking
thrombus
moving rod
rod
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CN202310414406.3A
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Chinese (zh)
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CN116439885A (en
Inventor
吴健平
刘红宝
刘柏杉
杨家乐
田宇
何宏宇
王鸿羽
黄聪兴
咸文龙
王国辉
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Weiming Medical Equipment Shanghai Co ltd
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Weiming Medical Equipment Shanghai Co ltd
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Priority to CN202310414406.3A priority Critical patent/CN116439885B/en
Publication of CN116439885A publication Critical patent/CN116439885A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Surgical Instruments (AREA)

Abstract

The application relates to the technical field of medical equipment, in particular to a multi-section telescopic intracranial stent, which comprises a conveying rod, a moving rod and a thrombus taking assembly; the conveying rod is arranged at the proximal end of the bracket and is provided with a hollow channel with two open ends; one end of the movable rod extends into the opening of the far end of the hollow channel, the other end extends towards the far end of the bracket, and the movable rod is connected with the conveying rod in a sliding way along the hollow channel; the thrombus taking assembly is of a self-expansion grid structure and comprises a first thrombus taking assembly and a second thrombus taking assembly, wherein the first thrombus taking assembly is fixedly connected with the distal end of the movable rod, the second thrombus taking assembly is arranged between the first thrombus taking assembly and the conveying rod, and the second thrombus taking assembly is in sliding connection with the movable rod; because movable rod and conveying rod sliding connection, second bolt subassembly and movable rod's sliding connection for first bolt subassembly is got the in-process that the movable rod was withdrawn to the first distance of getting between bolt subassembly and the second and is got the bolt subassembly and be adjusted, still form the state of centre gripping when catching thrombus, prevent that thrombus from droing.

Description

Multi-segment telescopic intracranial stent
Technical Field
The application relates to the technical field of medical appliances, in particular to a multi-section telescopic intracranial stent.
Background
The cerebral apoplexy is also called cerebral apoplexy, is a local cerebral dysfunction caused by acute cerebrovascular diseases, has the characteristics of high morbidity, high mortality, high disability rate and high recurrence rate after the clinical symptoms last for more than 24 hours, is well developed for people 50 years old and older, has the current rising morbidity of cerebral apoplexy in China year by year, and becomes the first cause of death in China.
Ischemic stroke is classified into acute stroke and chronic atherosclerotic stenotic stroke. Aiming at the first cerebral apoplexy, the main treatment means are medicine thrombolysis and interventional mechanical thrombolysis. However, the thrombolytic therapy is rarely used clinically at present due to the narrow time window and the occurrence of sequelae such as hemorrhage. So mechanical thrombus taking (stent thrombus taking) can be widely popularized and used.
In the prior art, the full-development thrombus taking bracket and thrombus taking device disclosed by Zhao Zhenxing have the publication number of CN207768466U, and the bracket has multiple development points, so that the bracket has large meshes and is convenient for catching a thrombus. However, in the process of catching thrombus, when the thrombus stent is embedded, under the action of forward blood flow, the large mesh stent is very easy to fall off from the small thrombus in the process of withdrawing. Thrombus escapes to the blood vessel at the far end, so that secondary stroke risks are easily caused, and greater risks are brought to the operation.
In the actual operation process, the probability of thrombus shedding is about 20%, because the risk of secondary stroke caused by thrombus shedding is about 60%, and the design of a stent capable of taking thrombus and preventing thrombus shedding is needed by combining the probability of occurrence of the thrombus shedding with the huge population base of China.
Disclosure of Invention
The object of the present application is to provide a multi-segmented telescopic intracranial stent to solve or alleviate the problems of the prior art described above.
In order to achieve the above object, the present application provides the following technical solutions:
A multi-section telescopic intracranial stent comprises a conveying rod, a moving rod and a thrombus taking assembly;
the conveying rod is arranged at the proximal end of the bracket and is provided with a hollow channel with two open ends;
one end of the moving rod extends into the conveying rod from the opening at the far end of the hollow passage, the moving rod is connected with the conveying rod in a sliding way along the hollow passage, and the other end of the moving rod extends towards the far end of the bracket;
The bolt taking assembly is of a self-expansion grid structure, the bolt taking assembly comprises a first bolt taking assembly and a second bolt taking assembly, the first bolt taking assembly is fixedly connected with the far end of the moving rod, the second bolt taking assembly is arranged between the first bolt taking assembly and the conveying rod, and the second bolt taking assembly is in sliding connection with the moving rod.
A multi-segment telescopic intracranial stent as described above, preferably, the hollow channels with two open ends are axially arranged along the conveying rod;
the thrombus taking assembly further comprises a third thrombus taking assembly, and the third thrombus taking assembly is fixedly connected with the distal end of the conveying rod.
In the multi-segment telescopic intracranial stent, preferably, two ends of the first thrombolysis component are contracted along the radial direction, the proximal end of the first thrombolysis component is contracted onto the moving rod along the radial direction, and the proximal end of the first thrombolysis component is fixedly sleeved at the distal end of the moving rod;
the distal end of the second thrombus taking assembly is opened to form an opening, the proximal end of the second thrombus taking assembly is radially contracted onto the moving rod, and the proximal end of the second thrombus taking assembly is sleeved on the moving rod in a sliding manner;
The distal end of the third thrombus taking assembly is opened to form an opening, and the proximal end of the third thrombus taking assembly is radially contracted onto the conveying rod; the proximal end of the third thrombus taking assembly is fixedly sleeved at the distal end of the conveying rod.
A multi-segmented telescopic intracranial stent as described above, wherein the mesh density of the first thrombolytic module is preferably gradually increased from the proximal end to the distal end.
In the multi-segment telescopic intracranial stent, preferably, the distal end of the first thrombolysis component is also contracted to a moving rod, the distal end of the first thrombolysis component 1 is sleeved on a moving rod 7, and the moving rod sequentially passes through the proximal end of the first thrombolysis component and the distal end of the first thrombolysis component to extend towards the distal end of the stent.
According to the multi-segment telescopic intracranial stent, preferably, the distal end of the moving rod is provided with the fourth developing part and the fixing part, the proximal end of the fourth developing part is fixedly connected with the distal end of the first thrombus taking assembly, and the distal end of the fourth developing part is fixedly connected with the distal end of the moving rod through the fixing part.
A multi-segmented telescopic intracranial stent as described above, wherein the first, second and third embolectomy assemblies preferably further extend axially outwardly during radial contraction.
In the multi-segment telescopic intracranial stent, preferably, a first limiter is arranged between the distal end of the second thrombus taking component and the proximal end of the first thrombus taking component, and the first limiter is fixedly connected to the moving rod; a second limiter is arranged between the proximal end of the second thrombus taking assembly and the distal end of the third thrombus taking assembly, and the second limiter is fixedly connected to the moving rod.
A multi-segmented telescopic intracranial stent as described above, preferably wherein the distance from the first stop to the proximal end of the second embolectomy assembly is less than the distance from the second stop to the proximal end of the third embolectomy assembly.
A multi-segment telescopic intracranial stent as described above, preferably further comprising an operating handle, the operating handle being provided with a regulator;
The operation handle is arranged at the opening of the proximal end of the hollow passage of the conveying rod, the operation handle is fixedly connected with the conveying rod, one end of the moving rod extending into the hollow passage extends into the operation handle, and the moving rod extends into the operation handle and is connected with the regulator.
Compared with the closest prior art, the technical scheme of the embodiment of the application has the following beneficial effects:
1. The moving rod is in sliding connection with the conveying rod, and the first thrombus taking assembly is in sliding connection with the moving rod based on the second thrombus taking assembly in the retracting process of the moving rod, so that the distance between the first thrombus taking assembly and the second thrombus taking assembly is adjusted, a clamping state is formed while thrombus is captured, and the thrombus is prevented from falling off;
2. the first thrombus taking component adopts a grid-shaped structure with two closed ends and is positioned at the tail end of the bracket and used for capturing escaping thrombus, the grid state structure of the first thrombus taking component is from near to far, grid density grouting is increased, capturing effect is further ensured, and thrombus taking efficiency is improved;
3. The multi-section design is adopted, so that the thrombus taking efficiency is further improved, and the stent can still be clung to the vessel wall even in a tortuous and complex vessel structure, so that deformation and thrombus falling are avoided.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this specification, illustrate embodiments of the application and together with the description serve to explain the application. Wherein:
FIG. 1 is a schematic illustration of the overall structure of a multi-segment telescopic intracranial stent, provided according to some embodiments of the present application;
FIG. 2 is an enlarged view of a portion of a delivery rod and a displacement rod of a multi-segment telescopic intracranial stent, provided in accordance with some embodiments of the present application;
FIG. 3 is a H-H cross-sectional view of a delivery rod and a displacement rod of a multi-segment telescopic intracranial stent, provided in accordance with some embodiments of the present application;
FIG. 4 is a cross-sectional view of a second connection point A-A of a multi-segment telescopic intracranial stent, provided in accordance with some embodiments of the present application;
FIG. 5 is a partial enlarged view at point B of a multi-segment telescopic intracranial stent, provided according to some embodiments of the present application;
FIG. 6 is a C-C cross-sectional view of a third connection point of a multi-segment telescopic intracranial stent, provided in accordance with some embodiments of the present application;
FIG. 7 is a cross-sectional view of a multi-segment telescopic intracranial stent D, E, provided in accordance with some embodiments of the present application;
FIG. 8 is an enlarged partial view of a multi-segment telescopic intracranial stent at point F, provided in accordance with some embodiments of the present application;
FIG. 9 is an enlarged partial view of a G point of a multi-segment telescopic intracranial stent, provided according to some embodiments of the present application;
FIG. 10 is a schematic illustration of a multi-segment telescopic intracranial stent thrombolysis provided according to some embodiments of the present application.
Reference numerals illustrate:
1-first thrombus removing component, 2-second thrombus removing component, 3-first limiter, 4-third thrombus removing component, 5-operating handle, 6-conveying rod, 7-moving rod, 8-fourth developing piece, 9-fixing piece, 10-second developing piece, 11-regulator, 12-stopper, 13-first connecting point, 14-second connecting point, 15-third connecting point, 16-first developing piece, 17-third developing piece, 18-second limiter and 19-thrombus.
Detailed Description
The application will be described in detail below with reference to the drawings in connection with embodiments. The examples are provided by way of explanation of the application and not limitation of the application. Indeed, it will be apparent to those skilled in the art that modifications and variations can be made in the present application without departing from the scope or spirit of the application. For example, features illustrated or described as part of one embodiment can be used on another embodiment to yield still a further embodiment. Accordingly, it is intended that the present application encompass such modifications and variations as fall within the scope of the appended claims and their equivalents.
In the following description, the terms "first/second/third" are used merely to distinguish between similar objects and do not represent a particular ordering of the objects, it being understood that the "first/second/third" may be interchanged with a particular order or precedence where allowed, to enable embodiments of the application described herein to be implemented in other than those illustrated or described herein.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs. The terminology used herein is for the purpose of describing embodiments of the present disclosure only and is not intended to be limiting of the present disclosure.
In the description of the present application, the terms "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", etc. refer to the orientation or positional relationship based on that shown in the drawings, merely for convenience of description of the present application and do not require that the present application must be constructed and operated in a specific orientation, and thus should not be construed as limiting the present application. The terms "coupled," "connected," and "configured" as used herein are to be construed broadly and may be, for example, fixedly connected or detachably connected; can be directly connected or indirectly connected through an intermediate component; either a wired electrical connection, a radio connection or a wireless communication signal connection, the specific meaning of which terms will be understood by those of ordinary skill in the art as the case may be.
The invention relates to a multi-section telescopic intracranial stent, which comprises a conveying rod 6, a moving rod 7 and a thrombus taking component; the conveying rod 6 is arranged at the proximal end of the bracket, and the conveying rod 6 is provided with a hollow channel with two open ends; one end of a moving rod 7 extends into the conveying rod 6 from the opening of the far end of the hollow passage, the moving rod 7 is connected with the conveying rod 6 in a sliding way along the hollow passage, and the other end of the moving rod 7 extends towards the far end of the bracket; the other end of the movable rod 7 extends towards the distal end of the bracket; the bolt taking assembly is of a self-expansion grid structure, the bolt taking assembly comprises a first bolt taking assembly 1 and a second bolt taking assembly 2, the first bolt taking assembly 1 is fixedly connected with the far end of a moving rod 7, the second bolt taking assembly 2 is arranged between the first bolt taking assembly 1 and a conveying rod 6, and the second bolt taking assembly 2 is in sliding connection with the moving rod 7.
According to the specific embodiment of the invention, as shown in fig. 1-10, the conveying rod 6 is in a circular tube structure, namely, a hollow channel which is opened at the far end of the conveying rod 6 and the near end of the conveying rod 6 is arranged along the axis of the conveying rod 6, and the conveying rod 6 is integrally formed by adopting a nickel-titanium alloy material or a high polymer material, so that the conveying rod 6 has good bending performance, force transmission performance, supporting performance and biocompatibility; the movable rod 7 is of a rod-shaped structure formed by integrally processing nickel-titanium super-elastic materials, and also has good bending performance, force transmission performance, supporting performance and biocompatibility, one end of the movable rod 7 extends into a hollow channel at the axial position of the conveying rod 6 from an opening at the distal end of the conveying rod 6 and extends towards the proximal end of the intracranial stent along the hollow channel of the conveying rod 6, the other end of the movable rod 7 extends towards the distal end of the intracranial stent, the movable rod 7 is in sliding connection with the conveying rod 6 through the hollow channel of the conveying rod 6, so that the movable rod 7 can relatively move axially along the hollow channel of the conveying rod 6, and the movable rod 7 and the conveying rod 6 are coaxially arranged.
The thrombus taking component is a columnar grid structure formed by processing nickel-titanium alloy materials with shape memory and weak development characteristics, can be integrally formed by laser cutting, and can also be formed into a whole by welding, specifically, after the intracranial stent is processed and formed, the processes of heat treatment, polishing and the like are performed, so that the smoothness of the surface of the stent and the overall mechanical property are improved, and the damage to blood vessels in the using process is avoided.
The bolt taking assembly comprises a first bolt taking assembly 1 and a second bolt taking assembly 2, wherein the first bolt taking assembly 1 is welded or glued at the far end of a moving rod 7, the second bolt taking assembly 2 is connected with the moving rod 7 between the first bolt taking assembly 1 and a conveying rod 6 in a sliding mode, the moving rod penetrates through a grid structure at one end of the second bolt taking assembly 2, one end of the second bolt taking assembly 2 is sleeved on the moving rod, and the second bolt taking assembly 2 can axially move along the moving rod 7 or rotate around the moving rod 7.
Because the nickel-titanium alloy material has a shape memory function, the thrombus taking component has two working states of contraction and expansion in the use process, in particular to the actual operation process:
1. Firstly, determining the position of thrombus 19, the peripheral vascular condition and the size of the thrombus 19 by a digital angiography technology, determining a stent access path, then performing vascular puncture, and introducing a micro-guide wire to the thrombus 19;
2. Then introducing the microcatheter along the microcatheter until the distal end of the microcatheter exceeds the length of the thrombus 19 by at least one first thrombolysis assembly 1, withdrawing the microcatheter;
3. According to the length of the thrombus 19 determined by angiography, the length of the moving rod 7 extending out of the conveying rod 6 is adjusted, and the relative positions of the moving rod 7 and the conveying rod 6 are fixed mechanically or manually, so that the length of the proximal end of the first thrombus taking assembly 1, which is far away from the distal end of the conveying rod 6, is not smaller than the length of the target thrombus 19;
4. the microcatheter is connected with the outer sheath tube through the connecting piece, the intracranial stent is pressed into the outer sheath tube, at the moment, the first bolt taking assembly 1 and the second bolt taking assembly 2 shrink into the outer sheath tube under the action of external force, meanwhile, as the second bolt taking assembly 2 is in sliding connection with the moving rod 7, in the pressing-in process of the stent, the second bolt taking assembly 2 moves to the connecting position of the moving rod 7 and the conveying rod 6 under the action of friction force;
5. Continuing to push the delivery rod 6, the intracranial stent enters the microcatheter through the outer sheath and reaches the region of the thrombus 19 along the microcatheter, wherein the proximal end of the first thrombus removal assembly 1 is positioned at the distal end of the target thrombus 19;
6. The microcatheter is retracted, the first thrombus taking component 1 and the second thrombus taking component 2 are restored to a preset columnar grid structure from a contracted state, and the second thrombus taking component 2 can be adjusted to a more stable state through axial movement or rotation in the process of expanding and contacting with thrombus 19;
7. The moving rod 7 is operated to retract at the opening of the proximal end of the conveying rod 6, the first thrombus taking component 1 fixedly connected to the distal end of the moving rod 7 also retracts, the distance between the first thrombus taking component 1 and the second thrombus taking component 2 is continuously shortened, the first thrombus taking component 1 and the second thrombus taking component 2 clamp the target thrombus 19, and the second thrombus taking component 2 retracts together with the moving rod 7 under the pushing action of the first thrombus taking component 1;
8. when the moving rod 7 is retracted to a proper distance, the moving rod 7 is fixed, the conveying rod 6 is retracted, the target thrombus 19 is retracted into the microcatheter together with the intracranial stent under the actions of capturing the second thrombus taking assembly 2, clamping the first thrombus taking assembly 1 and the second thrombus taking assembly 2 and pushing the first thrombus taking assembly 1, and finally is withdrawn out of the body together with the microcatheter, so that the whole thrombus taking process is completed.
In other embodiments of the present invention, the first and second thrombolysis modules 1 and 2 may have a grid structure such as curved, planar, conical, etc.
In other embodiments of the present invention, the conveying rod 6 may be provided with a C-shaped groove with two open ends on the top surface or the bottom surface along the axial direction, one end of the moving rod 7 extends into the groove of the conveying rod 6 through the opening of the conveying rod 6, and the moving rod 7 is slidably connected with the conveying rod 6 through the groove of the conveying rod 6.
In other embodiments of the present invention, the shaft of the moving rod 7 is provided with a groove along the axial direction, one end of the second bolt taking assembly 2 is processed into a shape matched with the groove, and the second bolt taking assembly 2 is matched with the groove of the moving rod 7 through the end part to realize sliding connection with the moving rod 7.
In other embodiments of the present invention, the hollow channel may not be disposed axially along the conveying rod 6, the hollow channel opening may not be disposed at two ends of the conveying rod 6, the moving rod 7 may be disposed not coaxially with the conveying rod 6, one end of the moving rod 7 extends into the hollow channel from the distal opening of the hollow channel, and the moving rod 7 and the conveying rod 6 are operated to relatively move at the proximal opening of the hollow channel to retract the moving rod 7.
In other embodiments of the present invention, the second thrombolytic device 2 may be movably disposed along the axial direction of the moving rod 7 according to different surgical requirements, and the second thrombolytic devices 2 are located between the first thrombolytic device 1 and the delivering rod 6.
The thrombus taking assembly further comprises a third thrombus taking assembly 4, and the third thrombus taking assembly 4 is fixedly connected with the distal end of the conveying rod 6.
The third thrombus taking component 4 is also of a self-expansion columnar grid structure, is made of nickel-titanium alloy material, is integrally formed by laser cutting or is integrally formed by welding, and then improves the whole mechanical system performance and smoothness by the procedures of heat treatment, polishing and the like; the third thrombus taking component 4 is welded or bonded and fixed at the distal end of the conveying rod 6, and is sequentially connected with the first thrombus taking component 1, the second thrombus taking component 2 and the third thrombus taking component 4 from the distal end of the intracranial stent to the proximal end of the intracranial stent.
After the intracranial stent is conveyed to the target thrombus 19 area through the microcatheter, the microcatheter is retracted, the first thrombus taking component 1, the second thrombus taking component 2 and the third thrombus taking component 4 are automatically expanded to be in a preset columnar grid structure, wherein the proximal end of the first thrombus taking component 1 is positioned at the distal end of the target thrombus 19, the second thrombus taking component 2 and the third thrombus taking component 4 are positioned at the position of the target thrombus 19, the second thrombus taking component 2 and the third thrombus taking component 4 are expanded to embed or comprise the target thrombus 19 for capturing, and the third thrombus taking component 4 is fixedly connected with the conveying rod 6, so that the target thrombus 19 can be kept fixed in position in the process of axially moving/rotating the second thrombus taking component 2 under the capturing of the third thrombus taking component 4, and the second thrombus taking component 2 is conveniently wrapped and embedded in the target thrombus 19, so that the capturing of the target thrombus 19 is realized.
The movable rod 7 is operated to retract at the opening at the proximal end of the conveying rod 6, the first thrombus taking component 1 fixedly connected to the distal end of the movable rod 7 also retracts, the distance between the first thrombus taking component 1 and the second thrombus taking component 2 is continuously shortened, the first thrombus taking component 1 and the second thrombus taking component 2 clamp the target thrombus 19, the second thrombus taking component 2 retracts together with the movable rod 7 under the pushing action of the first thrombus taking component 1, meanwhile, the distance between the second thrombus taking component 2 and the third thrombus taking component 4 is continuously shortened, the second thrombus taking component 2 and the third thrombus taking component 4 clamp the target thrombus 19 again, and the capturing capability of the stent on the target thrombus 19 is further enhanced.
In other embodiments of the present invention, the third embolectomy assembly 4 may also be a mesh structure such as curved, planar, conical, etc.
The two ends of the first thrombus taking assembly 1 are contracted in the radial direction, the proximal end of the first thrombus taking assembly 1 is contracted to the moving rod 7 in the radial direction, and the proximal end of the first thrombus taking assembly 1 is fixedly sleeved at the distal end of the moving rod 7 through welding or bonding; the distal end of the second thrombus taking assembly 2 is opened to form an opening, the proximal end of the second thrombus taking assembly 2 is radially contracted onto the moving rod 7, the diameter of the proximal end of the second thrombus taking assembly 2 after being radially contracted is slightly larger than that of the moving rod, and the proximal end of the second thrombus taking assembly 2 is slidably sleeved on the moving rod 7; the distal end of the third thrombus taking assembly 4 is opened to form an opening, and the proximal end of the third thrombus taking assembly 4 is radially contracted onto the conveying rod 6; the proximal end of the third thrombus taking component 4 is fixedly sleeved on the distal end of the conveying rod 6 through welding or bonding.
The movable rod 7 is coaxially arranged with the second bolt taking assembly 2 and the third bolt taking assembly 4, and the movable rod 7 sequentially penetrates through the third bolt taking assembly 4 and the second bolt taking assembly 2 along the axial direction of the movable rod and is fixedly connected with the proximal end of the first bolt taking assembly 1.
The end of the thrombus taking component extends outwards along the axial direction in the radial shrinkage process, and can be divided into a shrinkage part and a supporting part, wherein the diameter of the supporting part keeps consistent and extends along the axial direction of the thrombus taking component only, the diameter of the shrinkage part is in a trend of continuously shrinking in the process of extending outwards along the axial direction of the thrombus taking component, specifically, part of thrombus 19 can be broken under the embedding and wrapping of the thrombus 19 in the process of capturing thrombus 19, or part of thrombus 19 can fall off when the bracket is retracted and extruded in a curved blood vessel, the first thrombus taking component 1 is considered to be positioned at the far end of the movable rod 7 and is further positioned at the far end of the second thrombus taking component 2 and the far end of the third thrombus taking component 4, and the two ends of the first thrombus taking component 1 are both contracted along the radial direction in the process of extending outwards along the axial direction of the first thrombus taking component 1 to form two shrinkage parts, the diameters of the two shrinkage parts are kept consistent to form a supporting part, the whole of the first thrombus taking assembly 1 is of a closed columnar grid structure formed by clamping one supporting part by the two shrinkage parts, wherein the proximal end of the first thrombus taking assembly 1 extends outwards along the axial direction of the first thrombus taking assembly and radially shrinks to a first connecting point 13, the first connecting point 13 is positioned at the distal end of the moving rod 7, the proximal end of the first thrombus taking assembly 1 is fixedly connected with the distal end of the moving rod 7 at the position of the first connecting point 13, the proximal ends of the second thrombus taking assembly 2 and the proximal end of the third thrombus taking assembly 4 also shrink outwards along the axial direction of the second thrombus taking assembly 2 and the distal end of the third thrombus taking assembly 4 to form a shrinkage part, the distal ends of the second thrombus taking assembly 2 and the third thrombus taking assembly 4 extend outwards along the axial direction of the second thrombus taking assembly 4 to form an opening to form a supporting part, the whole of an open columnar grid structure formed by one proximal shrinkage part and one distal end supporting part, the proximal end of the third thrombolysis component 4 extends outwards along the axial direction and radially contracts to a third connection point 15, the third connection point 15 is located at the distal end of the conveying rod 6, the proximal end of the third thrombolysis component 4 is fixedly connected with the distal end of the conveying rod 6 at the third connection point 15, the proximal end of the second thrombolysis component 2 extends outwards along the axial direction and radially contracts to a second connection point 14, the second connection point 14 is located on the moving rod 7 between the first connection point 13 and the third connection point 15, and the proximal end of the second thrombolysis component 2 is slidably connected with the moving rod 7 at the second connection point 14.
In other embodiments of the present invention, the moving rod 7 is not coaxially arranged with the second and third thrombectomy assemblies 2,4, and the moving rod penetrates the proximal end of the second thrombectomy assembly 2 only at the second connection point 14, penetrates the proximal end of the third thrombectomy assembly 4 at the third connection point 15, and the second and third thrombectomy assemblies 2,4 are respectively arranged on the same side or both sides of the moving rod 7.
The outer diameter of the shrinkage part of each thrombus taking component is smaller than that of the supporting part of the adjacent thrombus taking component, so that in the retracting process of the moving rod 7, the shrinkage part of the proximal end of the distal thrombus taking component can extend into the supporting part of the distal end of the adjacent thrombus taking component at the proximal end of the adjacent thrombus taking component, the limit can extend into the shrinkage part of the proximal end of the adjacent thrombus taking component, the clamping area of the thrombus taking component on the target thrombus 19 is increased, the clamping effect between the thrombus taking components is further enhanced, the supporting parts of the adjacent thrombus taking components can be mutually contacted or overlapped in the continuous retracting process of the moving rod 7, a closed columnar grid structure with larger gauge can be formed, and the capturing effect of the intracranial stent on the target thrombus 19 is further enhanced.
In other embodiments of the present invention, the end of the thrombus taking assembly can only shrink radially and does not extend axially, that is, for the first thrombus taking assembly 1, both ends of the first thrombus taking assembly only shrink radially, the shrinkage part does not extend axially, and the whole first thrombus taking assembly 1 is a closed columnar grid structure formed by a supporting part; for the second and third thrombus taking assemblies 4, the proximal ends are only radially contracted, the contracted parts are not axially extended, the distal ends are opened to form openings, and the second and third thrombus taking assemblies are integrally formed into an open columnar grid structure formed by a supporting part. In the retracting process of the moving rod 7, the thrombus taking component does not extend into the far-end supporting parts of the adjacent thrombus taking components, and the supporting parts of the adjacent thrombus taking components can be contacted with each other in the retracting process, so that a closed columnar grid structure with a larger gauge model is formed.
In other embodiments of the present invention, the second and third thrombolytic modules 2 and 4 can also radially shrink at both ends, and the whole of the first thrombolytic module 1, the second thrombolytic module 2 and the third thrombolytic module 4 is a closed columnar grid structure formed by a supporting portion, and in the retracting process of the moving rod 7, the supporting portions of adjacent thrombolytic modules can mutually contact to form a closed columnar grid structure with larger gauge.
The first thrombus taking component 1 is gradually increased in grid density from the proximal end to the distal end, wherein the position with sparse grid density is located at the proximal end of the first thrombus taking component 1, so that thrombus 19 can enter a closed columnar grid structure of the first thrombus taking component 1 conveniently, the position with dense grid is located at the distal end of the first thrombus taking component 1, thrombus 19 entering the closed columnar grid structure is prevented from escaping again, the proximal end with sparse grid density is matched with the distal end with dense grid density, and the capability of the first thrombus taking component 1 for capturing thrombus 19 and preventing escaping again is enhanced.
In order to improve the use effect of the first thrombus taking assembly 1 and the integrity of the intracranial stent, the distal end of the first thrombus taking assembly 1 is also contracted to the moving rod 7, the distal end of the first thrombus taking assembly 1 is fixedly sleeved on the moving rod 7, the moving rod 7 sequentially penetrates through the proximal end of the first thrombus taking assembly 1, the distal end of the first thrombus taking assembly 1 extends to the distal end of the stent, and the first thrombus taking assembly 1 and the moving rod 7 are coaxially arranged.
After the intracranial stent reaches the target thrombus 19 through the microcatheter and is retracted, as the two ends of the first thrombus taking component 1 are fixedly connected to the moving rod 7, the first thrombus taking component 1 expands into a preset grid structure at the far end of the target thrombus 19, and has stronger supportability and shape maintenance capability, even if the intracranial stent is retracted in a bent blood vessel, the intracranial stent cannot be obviously deformed when being extruded by the side wall of the blood vessel.
In other embodiments of the present invention, the moving rod 7 and the first thrombolysis assembly 1 may be disposed in different axes, the moving rod 7 only passes through the proximal end of the first thrombolysis assembly 1 and the distal end of the first thrombolysis assembly 1 in sequence, and does not pass through the first thrombolysis assembly 1, and the first thrombolysis assembly 1 is disposed at one side of the moving rod 7.
In order to facilitate judging the specific position of the stent in the blood vessel, the distal end of the moving rod 7 is provided with a fourth developing part 8 and a fixing part 9, the proximal end of the fourth developing part 8 is fixedly connected with the distal end of the first thrombus taking assembly 1 through welding or bonding, and the distal end of the fourth developing part 8 is fixedly connected with the distal end of the moving rod 7 through the fixing part 9.
The fourth developing part 8 is specifically made of radiopaque noble metals such as platinum iridium, platinum tungsten, tantalum, gold and the like, and is provided with a developing spring with certain flexibility, and the developing spring is sleeved at the far end of the movable rod 7; the fixing piece 9 is a spherical cap made of elastic high polymer material with biocompatibility, and the distal end of the moving rod 7 and the distal end of the developing spring extend into the spherical cap and are fixedly connected through glue so as to prevent the moving rod 7 from damaging the inner wall of a blood vessel.
Since the distal end of the first thrombus taking assembly 1 is fixedly sleeved on the moving rod 7, the position of the developing spring on the moving rod 7 is also fixed, and the developing spring and the moving rod 7 do not move relatively.
In other embodiments of the present invention, the distal end of the first thrombolysis component 1 is slidably sleeved on the moving rod 7, the first thrombolysis component 1 is coaxially arranged with the moving rod 7, and since the distal end of the developing spring is fixedly connected with the distal end of the first thrombolysis component 1, the distal end of the developing spring can move along the axial direction of the moving rod 7 together with the distal end of the first thrombolysis component 1, after the intracranial stent reaches the target thrombus 19 position via the microcatheter, the elastic force of the developing spring is preset in advance after the microcatheter is retracted, so that the first thrombolysis component 1 expands under the limiting action of the elastic force of the elastic element and the pressure of the inner wall of the blood vessel at the same time, forming a grid structure matched with the size of the inner wall of the blood vessel; when the intracranial stent is retracted to the curved blood vessel, the elastic element can assist to maintain the shape of the first thrombus taking assembly 1 by self elastic force so as to prevent the thrombus taking assembly structure from being deformed under pressure, thereby leading to the falling-off of the target thrombus 19.
In other embodiments of the present invention, a plurality of first developing members 16 are further uniformly disposed in the circumferential direction of the first thrombolysis assembly 1, a plurality of second developing members 10 are further uniformly disposed in the circumferential direction of the second thrombolysis assembly 2, a plurality of third developing members 17 are further uniformly disposed in the circumferential direction of the third thrombolysis assembly 4, and the first, second and third developing members 17 are developing rings made of radiopaque noble metals such as platinum iridium, platinum dock, tantalum and gold, so as to facilitate observation of the deployment state of the thrombolysis assembly in blood vessels, and the developing rings are fixedly connected to the thrombolysis assembly by physical pressing, winding and the like.
In other embodiments of the present invention, the developing member disposed at the distal end of the moving rod 7 may also be a developing ring made of radiopaque noble metals such as platinum iridium, platinum dock, tantalum, gold, etc., and the developing ring is fixedly connected to the distal end of the moving rod 7 and the thrombus removing assembly by means of physical pressing and holding, winding, etc., specifically, the proximal end of the developing ring is fixedly connected to the distal end of the first thrombus removing assembly 1, and the distal end of the developing ring is fixedly connected to the distal end of the moving rod 7 by a ball cap.
A first limiter 3 is arranged between the distal end of the second thrombus taking assembly 2 and the proximal end of the first thrombus taking assembly 1, and the first limiter 3 is fixedly connected to a moving rod 7; a second limiter 18 is arranged between the proximal end of the second thrombus taking assembly 2 and the distal end of the third thrombus taking assembly, and the second limiter 18 is fixedly connected to the movable rod 7.
In order to prevent excessive clamping between the thrombus taking assemblies and to enable the target thrombus 19 to break and fall off, a first limiter 3 and a second limiter 18 are fixedly arranged at a certain distance between the distal end of the second thrombus taking assembly 2 and the proximal end of the second thrombus taking assembly 2, and meanwhile, in order to facilitate further observation of the withdrawing state of the moving rod 7, the first limiter 3 and the second limiter 18 are annular structures made of non-transmitting wire materials and are fixedly sleeved on the moving rod 7 through welding or bonding.
In the retracting process of the moving rod 7, the first bolt taking assembly 1 and the first limiter 3 retract along with the moving rod 7, the distance between the second bolt taking assembly 2 and the first bolt taking assembly 1 is continuously shortened under the retracting action of the moving rod 7, but the distance between the second bolt taking assembly 2 and the first bolt taking assembly 1 does not change any more when the first limiter 3 moves to the proximal end of the second bolt taking assembly 2, the second bolt taking assembly 2 can retract under the pushing action of the first limiter 3 and the first bolt taking assembly 1, and the moving rod 7 is stopped when the second limiter 18 retracts to the proximal end of the third bolt taking assembly 4 along with the moving rod 7, namely, the fixed connection position of the distal end of the conveying rod 6 or the third bolt taking assembly 4.
In order to achieve a good clamping state between the second and third thrombus removing assemblies 2 and 4, further improve the effect of capturing thrombus 19 by the stent, the distance from the first limiter 3 to the proximal end of the second thrombus removing assembly 2 is smaller than the distance from the second limiter 18 to the proximal end of the third thrombus removing assembly 4, so that after the first limiter 3 moves to the proximal end of the second thrombus removing assembly 2, the moving rod 7 can be further retracted until the second limiter 18 moves to the proximal end of the third thrombus removing assembly 4.
The intracranial stent also comprises an operating handle 5, and the operating handle 5 is provided with a regulator 11; the operating handle 5 sets up in conveying pole 6 cavity passageway proximal end opening part, operating handle 5 and conveying pole 6 fixed connection, and the one end that movable rod 7 stretched into conveying pole 6 cavity passageway passes conveying pole 6 cavity passageway to extend to operating handle 5 inside, movable rod 7 stretches into operating handle 5 inside and is connected with regulator 11, and regulator 11 is the rolling regulator, through operating the rolling regulator, can drive movable rod 7 and follow conveying pole 6 cavity passageway and slide.
In other embodiments of the present invention, the operating handle 5 is further provided with a stopper 12, the moving lever 7 is extended into the operating handle 5 and connected to the stopper 12, and after the operating handle 5 is moved to a certain distance by operating the moving lever 7 through the adjuster 11, the moving lever 7 can be locked by pressing the stopper 12, which plays a role of fixing the moving lever 7, and the rolling adjuster 11 can be operated again only after releasing the stopper 12.
In other embodiments of the present invention, the operating handle 5 is externally provided with stripes for increasing the friction coefficient, which is convenient for the operator to hold, making it more close to the ergonomic requirement.
In other embodiments of the present invention, the proximal end of the movable rod 7 may not pass through the hollow passage of the conveying rod 6, and the distal end of the operating handle 5 may extend from the proximal opening of the hollow passage into the hollow passage of the conveying rod 6 to be connected to the proximal end of the movable rod 7, and the proximal end of the movable rod 7 extends into the interior of the operating handle 5 in the hollow passage of the conveying rod 6 to be connected to the regulator 11.
The above description is only of the preferred embodiments of the present application and is not intended to limit the present application, but various modifications and variations can be made to the present application by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the protection scope of the present application.

Claims (6)

1. The multi-section telescopic intracranial stent is characterized by comprising a conveying rod, a moving rod and a thrombus taking assembly;
the conveying rod is arranged at the proximal end of the bracket and is provided with a hollow channel with two open ends;
one end of the moving rod extends into the conveying rod from the opening at the far end of the hollow passage, the moving rod is connected with the conveying rod in a sliding way along the hollow passage, and the other end of the moving rod extends towards the far end of the bracket;
the thrombus taking assembly is of a self-expansion grid structure and comprises a first thrombus taking assembly and a second thrombus taking assembly, the first thrombus taking assembly is fixedly connected with the distal end of the moving rod, the second thrombus taking assembly is arranged between the first thrombus taking assembly and the conveying rod, and the second thrombus taking assembly is in sliding connection with the moving rod;
the thrombus taking assembly further comprises a third thrombus taking assembly, and the third thrombus taking assembly is fixedly connected with the distal end of the conveying rod;
The two ends of the first thrombus taking assembly are contracted along the radial direction, the proximal end of the first thrombus taking assembly is contracted onto the moving rod along the radial direction, and the proximal end of the first thrombus taking assembly is fixedly sleeved at the distal end of the moving rod;
the distal end of the second thrombus taking assembly is opened to form an opening, the proximal end of the second thrombus taking assembly is radially contracted onto the moving rod, and the proximal end of the second thrombus taking assembly is sleeved on the moving rod in a sliding manner;
The distal end of the third thrombus taking assembly is opened to form an opening, and the proximal end of the third thrombus taking assembly is radially contracted onto the conveying rod; the proximal end of the third thrombus taking assembly is fixedly sleeved at the distal end of the conveying rod;
The distal end of the first thrombus taking assembly also contracts onto the moving rod, the distal end of the first thrombus taking assembly is sleeved on the moving rod in a sliding manner, and the moving rod sequentially penetrates through the proximal end of the first thrombus taking assembly and the distal end of the first thrombus taking assembly to extend towards the distal end of the bracket;
the distal end of the moving rod is provided with a fourth developing part and a fixing part, the proximal end of the fourth developing part is fixedly connected with the distal end of the first thrombus taking assembly, and the distal end of the fourth developing part is fixedly connected with the distal end of the moving rod through the fixing part;
A first limiter is arranged between the distal end of the second thrombus taking assembly and the proximal end of the first thrombus taking assembly, and the first limiter is fixedly connected to the moving rod; a second limiter is arranged between the proximal end of the second thrombus taking assembly and the distal end of the third thrombus taking assembly, and the second limiter is fixedly connected to the moving rod.
2. The multi-segment telescopic intracranial stent of claim 1, wherein the hollow channels with two open ends are axially arranged along the delivery rod.
3. The multi-segment telescopic intracranial stent of claim 1, wherein the lattice density of the first embolectomy assembly increases gradually from the proximal end to the distal end.
4. The multi-segment telescopic intracranial stent of claim 1, wherein the first, second and third embolectomy assemblies further extend axially outward during radial contraction.
5. The multi-segment telescopic intracranial stent of claim 1, wherein the distance from the first stop to the proximal end of the second embolectomy assembly is less than the distance from the second stop to the proximal end of the third embolectomy assembly.
6. The multi-segment telescopic intracranial stent according to any one of claims 1 to 5, further comprising an operating handle, the operating handle being provided with a regulator;
The operation handle is arranged at the opening of the proximal end of the hollow passage of the conveying rod, the operation handle is fixedly connected with the conveying rod, one end of the moving rod extending into the hollow passage extends into the operation handle, and the moving rod extends into the operation handle and is connected with the regulator.
CN202310414406.3A 2023-04-18 2023-04-18 Multi-segment telescopic intracranial stent Active CN116439885B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106618676A (en) * 2016-12-30 2017-05-10 上海加奇生物科技苏州有限公司 Intravascular thrombus withdrawing device
CN112890915A (en) * 2020-12-30 2021-06-04 上海融脉医疗科技有限公司 Intravascular multi-segment embolectomy support and conveying device thereof
CN114343781A (en) * 2020-10-13 2022-04-15 山东瑞安泰医疗技术有限公司 Multi-section umbrella-shaped intracranial thrombus extraction device
CN115040197A (en) * 2022-06-23 2022-09-13 适介医疗科技(广州)有限公司 Thrombus capture system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106618676A (en) * 2016-12-30 2017-05-10 上海加奇生物科技苏州有限公司 Intravascular thrombus withdrawing device
CN114343781A (en) * 2020-10-13 2022-04-15 山东瑞安泰医疗技术有限公司 Multi-section umbrella-shaped intracranial thrombus extraction device
CN112890915A (en) * 2020-12-30 2021-06-04 上海融脉医疗科技有限公司 Intravascular multi-segment embolectomy support and conveying device thereof
CN115040197A (en) * 2022-06-23 2022-09-13 适介医疗科技(广州)有限公司 Thrombus capture system

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