WO2022253364A1

WO2022253364A1 - Delivery guide wire and blood flow guiding apparatus

Info

Publication number: WO2022253364A1
Application number: PCT/CN2022/113732
Authority: WO
Inventors: 曾凡艳; 石华; 贺心知; 李志刚; 王国辉
Original assignee: 上海心玮医疗科技股份有限公司
Priority date: 2021-08-23
Filing date: 2022-08-19
Publication date: 2022-12-08
Also published as: CN114451946A

Abstract

A delivery guide wire and a blood flow guiding apparatus. The delivery guide wire comprises a pressing and holding section (1) and a developing section (2) which are formed continuously. The pressing and holding section (1) comprises a bendable mandrel (11). At least one flexible friction pad (12) is provided at a position near the proximal end portion of the mandrel (11), and at least one expansion body (13) is provided at a position near the distal end portion of the mandrel (11). The expansion body (13) has, along the radial direction of the mandrel (11), the ability to automatically expand outward. The mandrel (11) and the end portion of the expansion body (13) near the friction pad (12) are fixedly connected on the axial direction. The mandrel (11) and the end portion of the expansion body (13) far away from the friction pad (12) are slidably connected on the axial direction. At least one protective body (211, 212) is provided at the proximal end of the developing section (2). The delivery guide wire can be used in the blood flow guiding apparatus. Thus, good flexibility and blood vessel super-selection performance can be maintained, and a stent can be delivered, according to different usage scenarios, to a designated position in the blood vessels of a patient.

Description

A delivery guide wire and blood flow guiding device

technical field

Embodiments of the present disclosure relate to the field of medical equipment, and in particular, to a delivery guide wire and a blood flow guiding device.

Background technique

The treatment of intracranial aneurysms has gone through the development stages of early coil packing, balloon-assisted coil packing, and mid-term stent-assisted coil packing. At present, blood flow guiding devices are widely used for the treatment of intracranial aneurysms. The design of the current blood flow guiding devices adopts the method of braiding filaments, so it has a high metal coverage, so that it can be placed at the position of the aneurysm. Spread evenly in the blood vessels of the aneurysm, the woven mesh intercepts the blood flow, changes the direction of the blood flow, guides the blood flow to flow in the direction of the stent guide, and prevents the blood flow from continuing to wash into the aneurysm, but it will further thin the blood vessel wall , increasing the risk of rupture

Current blood flow diversion devices generally have the following disadvantages:

(1) The angle of the distal end of the delivery guide wire is too small. During the operation, the doctor's limited attention is mainly focused on the release, deployment and apposition of the stent. In the process of pushing the distal end, the tortuous blood vessel or obstacle is encountered, but the operator does not notice it, and keeps pushing the guide wire. The distal end of the nearly straight delivery guide wire has the risk of puncturing the blood vessel. The blood vessel bleeds after being punctured by the guide wire, resulting in cerebral hemorrhage. Since the bleeding point is at the distal end of the intracranial blood vessel, neither the microguide wire nor the coil can be put in place and cannot be remedied, so this bleeding is fatal;

(2) If both ends of the dense-mesh stent are open (the braided mesh is cut to form a broken end), and no new development point design is added at both ends, the delivery of the stent mainly depends on the design of the delivery guide wire. There are two main points in the design of the delivery guide wire. First, the distal end of the stent is wrapped, and a friction pad is designed at the proximal end. The friction pad is inside the stent to stretch the stent so that it fits the inner wall of the delivery catheter, which reduces the risk of stent The frictional force at the distal end increases the forward pushing force of the stent, and at the same time, because the distal end of the stent is wrapped, the stent is not easy to slip during the forward pushing process. The wrapping design of the distal end also has the problem that the stent cannot be opened in the tortuous blood vessel. If the wrapping at the distal end of the stent cannot be opened, the guide wire cannot be withdrawn from the blood vessel, even if the stent and guide wire are recovered Access to the sheath is also difficult, which will bog down the clinician and take a lot of time to solve this difficult problem. And it is not always able to be properly solved; second, the distal end of the delivery guide wire does not wrap the stent, and multiple friction pads are designed at the proximal end of the stent to further increase the fit between the stent and the inner wall of the delivery catheter. This fit enables the stent to be pushed forward from the microcatheter. This design avoids the problem that the distal end of the stent cannot be opened in some special blood vessels due to being wrapped, but there is a large gap between the distal end of the stent and the distal end of the guide wire (in order to increase the flexibility of the distal end of the delivery guide wire , usually as thin as a nerve microguide wire), the existence of the gap will cause the dense mesh stent to be pushed forward in the microcatheter, the stent will bend as a whole, and there will always be a tendency to move backwards, and the pushing force of the stent comes entirely from the stent near the stent. The support force of the end friction pad will cause the braided wire at the proximal part of the stent to bear too much force, and these forces will be transmitted forward, which will make the whole stent receive uneven force. The external performance is the push of the stent in the microcatheter The force increases, and even after the stent is pushed for a certain stroke, the stent and the friction pad are relatively displaced (the stent moves to the proximal end of the delivery guide wire), and after the stent is released, the distal end of the stent is prone to insufficient opening, or the proximal end of the stent is not fully opened, or even Insufficient simultaneous proximal and distal opening;

(3) Due to the large number of models and specifications of the dense mesh support, the length of the long specification support is greater than 40mm, and the span on the conveying guide wire is large. If the force is uneven during the conveying process, it is easy to cause uneven distribution of the braided wire In some cases, the uneven distribution of the braided filaments will lead to insufficient release and deployment of the stent, or poor adhesion to the wall, bending and discounting and other problems.

Contents of the invention

In view of the above-mentioned problems in the prior art, embodiments of the present disclosure provide a delivery guide wire and a blood flow guiding device to solve the problems in the prior art.

In order to solve the above problems, the technical solution provided by the embodiments of the present disclosure is: a delivery guide wire, including a crimping section and a developing section that are continuously formed, and the crimping section includes a bendable mandrel. At least one flexible friction pad is arranged near its proximal end, and at least one expansion body is arranged near the distal end of the mandrel, and the expansion body has a diameter along the radial direction of the mandrel. The ability to self-expand outwards, the end of the expansion body close to the friction pad is fixedly connected to the mandrel in the axial direction, the end of the expansion body away from the friction pad is connected to the The mandrels are slidably connected in the axial direction, and at least one protective body is arranged at the proximal end of the developing section.

In some embodiments, the mandrel is a tubular structure with a fixed extension length or a telescoping tubular structure.

In some embodiments, the friction pad is arranged on the mandrel, its relative position with the mandrel is fixed in the axial direction, and it rotates around the mandrel in the radial direction of the mandrel 11 or is opposite to the mandrel. The mandrel is fixed.

In some embodiments, the friction pad is fixed on the mandrel in a wrapping manner or a multi-turn coil spring is arranged around the mandrel, and the friction pad is fixed on the coil spring.

In some embodiments, the coil spring is made of platinum-iridium alloy.

In some embodiments, when there are multiple friction pads, multiple friction pads are sequentially arranged on the mandrel.

In some embodiments, the friction pad adopts at least one structure among cylinder, spindle and sphere.

In some embodiments, the friction pad is made of polymer material.

In some embodiments, the polymer material is TPU material or silicone material.

In some embodiments, the number of the expansion bodies is multiple, and the plurality of expansion bodies are arranged sequentially on the mandrel near its distal end.

In some embodiments, the expansion body adopts a metal cage structure.

In some embodiments, the expansion body adopts a polymer elastic body with a hollow structure, and the polymer elastic body is arranged as a single-layer porous structure.

In some embodiments, when the expansion body adopts the structure of a metal cage, it has interconnected branches, and the developing material is disposed on the branches.

In some embodiments, the developing material is at least one of platinum-iridium alloy, platinum-tungsten alloy, gold, and tantalum alloy.

In some embodiments, the shape of the developing material is at least one of sheet shape, filament shape and ring shape.

In some embodiments, according to the shape of the developing material, the mounting method of the developing material on the branch adopts at least one of inlay, winding, and ring.

In some embodiments, the distal end of the developing section is configured as an arc structure, and the arc structure is a U-shaped structure or a J-shaped structure.

In some embodiments, the shape of the protective body is at least one of a sphere, an ellipsoid, or a cone.

In some embodiments, the material of the protective body is one of tin, UV glue, high molecular polymer, and developable alloy material.

In some embodiments, a first protective body and a second protective body are arranged near the developing section, the first protective body is arranged away from the crimping section, and the second protective body is close to the crimping section segment settings.

An embodiment of the present disclosure also provides a blood flow guiding device, which includes an introduction sheath, a stent, and the delivery guide wire according to any one of the above claims, the delivery guide wire is set in the introduction sheath, and The stent can be disposed within the delivery guidewire.

The embodiments of the present disclosure can be used in the blood flow guiding device, not only can maintain good flexibility and blood vessel super-selection performance, but also can deliver the stent to a designated position in the patient's blood vessel according to different usage scenarios.

Description of drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present disclosure or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only These are some embodiments described in the present disclosure. Those skilled in the art can also obtain other drawings based on these drawings without any creative effort.

FIG. 1 is a schematic structural view of a delivery guide wire according to an embodiment of the present disclosure;

Fig. 2 is a structural schematic diagram of a delivery guide wire according to an embodiment of the present disclosure

3 is a schematic structural diagram of a delivery guide wire according to an embodiment of the present disclosure;

4 is a schematic structural diagram of a delivery guide wire according to an embodiment of the present disclosure;

5 is a schematic structural diagram of a delivery guide wire according to an embodiment of the present disclosure;

6 is a schematic structural diagram of a delivery guide wire according to an embodiment of the present disclosure;

FIG. 7 is a schematic structural diagram of a delivery guide wire according to an embodiment of the present disclosure.

Detailed ways

Various aspects and features of the present application are described herein with reference to the accompanying drawings.

It should be understood that various modifications may be made to the embodiments applied for herein. Accordingly, the above description should not be viewed as limiting, but only as exemplifications of embodiments. Those skilled in the art will envision other modifications within the scope and spirit of the application.

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments of the application and, together with the general description of the application given above and the detailed description of the embodiments given below, serve to explain the embodiments of the application. principle.

These and other characteristics of the present application will become apparent from the following description of preferred forms of embodiment given as non-limiting examples with reference to the accompanying drawings.

It should also be understood that, while the application has been described with reference to a few specific examples, those skilled in the art will be able to implement certain other equivalents of the application.

The above and other aspects, features and advantages of the present application will become more apparent in view of the following detailed description when taken in conjunction with the accompanying drawings.

Specific embodiments of the present application are hereinafter described with reference to the accompanying drawings; however, it should be understood that the applied embodiments are merely examples of the present application, which can be implemented in various ways. Well-known and/or repetitive functions and constructions are not described in detail to avoid obscuring the application with unnecessary or redundant detail. Therefore, specific structural and functional details disclosed herein are not intended to be limiting, but merely as a basis for the claims and as a representative basis for teaching one skilled in the art to variously employ the present invention in virtually any suitable detailed structure. Application.

This specification may use the phrases "in one embodiment," "in another embodiment," "in yet another embodiment," or "in other embodiments," which may refer to the same or one or more of the different embodiments.

The first embodiment of the present disclosure provides a delivery guide wire. The delivery guide wire here is suitable for use in a blood flow guiding device. The tube is inserted into the patient's body, and then the introduction sheath is extended into the blood vessel of the patient and the medical implant such as a stent set in the delivery guide wire is delivered to a predetermined position in the patient's body. As shown in Figure 1, the delivery guide wire includes a continuously formed crimping section 1 and a developing section 2, the crimping section 1 includes a mandrel 11, the mandrel 11 is a bendable tubular structure, the core The interior of the shaft 11 is used to pass through, for example, a bracket, wherein the mandrel 11 here has a proximal end and a distal end, the proximal end refers to the end of the mandrel 11 away from the developing section 2, It refers to a position close to operators such as doctors. The proximal end of the mandrel 11 can be connected with an operating handle, for example, to facilitate operations by operators such as doctors. The distal end refers to the position of the mandrel. In 11, the end near the developing section 2 refers to a position close to the operating position for the patient, so that the developing section 2 is arranged outside the distal end of the mandrel 11, and It is fixedly connected with the crimping section 1 .

Specifically, in a preferred embodiment, the mandrel 11 has a fixed extension length, and the extension length here can be determined according to the distance of the patient's operating position, so that it is not affected by the crimping of the stent on the guide wire. Instead, there is a variation in length, and moreover, the cross-sectional dimensions at any position along the extended length of the mandrel 11 are the same. In another preferred embodiment, in order to be able to adjust the extension length of the mandrel 11 according to different patients, the mandrel 11 can adopt a retractable tubular structure, for example, a plurality of tubular structures are nested to form the core shaft 11, which can facilitate the adjustment of the extension length of the mandrel 11, so as to be used in different patients or in more operation scenarios.

Further, at least one flexible friction pad 12 is arranged on the mandrel 11 near the proximal end, the friction pad 12 is arranged on the mandrel 11, and it is coaxial with the mandrel 11 The upward relative position is fixed, and can rotate around the mandrel 11 in the radial direction of the mandrel 11 or be fixed relative to the mandrel 11; the friction pad 12 here has a certain thickness, and it is used when the After the delivery guide wire is inserted into the patient's blood vessel, friction force can be formed with the blood vessel wall through the friction pad 12, and the delivery guide wire can be fixed in the blood vessel under the action of the friction force.

Of course, the way of fixing the friction pad 12 on the mandrel 11 here can be in any way, for example, in a preferred embodiment, the friction pad 12 can be fixed on the mandrel in a wrapping manner. 11; in another preferred embodiment, on the mandrel 11, a multi-turn coil spring is arranged around the mandrel 11, and the friction pad 12 is fixed on the coil spring; in addition, the coil spring here can be, for example, Made of platinum-iridium alloy.

In addition, as shown in FIG. 2 , in order to increase the friction between the delivery guide wire and the blood vessel wall of the human body, thereby improving the fixing effect of the delivery guide wire in the blood vessel, the mandrel 11 can A plurality of said friction pads 12 are arranged on it. When the number of the friction pads 12 is multiple, multiple friction pads 12 can be arranged on the mandrel 11 in turn. In the embodiment of the present disclosure, the number of the friction pads 12 is generally selected as 2-5. , for example, 3 can be selected.

Further, the friction pad 12 can adopt a variety of structures with a certain thickness such as cylinders, spindles, and spheres that will not damage the blood vessels, so as to form a frictional force with the blood vessel walls of the blood vessels to fix the delivery. guide wire. In order to be able to fix the function of the delivery guide wire in the blood vessel without damaging the blood vessel wall, the friction pad 12 can be made of elastic material; The pad 12 is made of polymer material, for example, any one of TPU (thermoplastic polyurethane elastomer rubber) material, silicone material and the like can be used.

The friction pad 12 here can be made of a single-layer structure using the same material, or a double-layer structure can be made of different materials, so that the inside maintains a certain hardness, while the outside has a certain flexibility, wherein the friction pad The hardness of the inner structure of the friction pad 12 close to the mandrel 11 is greater than the hardness of the outer structure of the friction pad 12 away from the mandrel 11, where the inner structure and the outer structure are axially , circumferentially and radially are fixedly connected to each other.

At least one expansion body 13 is provided on the mandrel 11 close to the distal end. It should be noted that the position where the expansion body 13 is provided on the mandrel 11 is, for example, the loading section of the stent. Here, The expansion body 13 is arranged outside the mandrel 11 , and the bracket is located inside the mandrel 11 . Wherein, the expansion body 13 is used to expand at a predetermined position in the blood vessel to expand the blood vessel, and the end of the expansion body 13 close to the friction pad 12 and the core shaft 11 are axially fixed connection, the end of the expansion body 13 away from the friction pad 12 is slidably connected to the mandrel 11 in the axial direction. Wherein, the fixing method between the expansion body 13 and the mandrel 11 can be adhesive connection, welding, or physical kneading or pressing; as a preferred method, adhesive bonding is adopted. .

Further, the expansion body 13 here has scalability, that is, the outward expansion ability and elastic support force along the radial direction of the mandrel 11, so that the expansion body 13 can present Smaller volume, in other usage scenarios, the volume can be automatically increased, so that the volume can be changed according to different usage scenarios. Specifically, when the stent is loaded in the delivery guide wire and the introduction sheath, the expansion body also shrinks and becomes thinner, and is distributed inside the stent, providing a uniform support force outward, so that the stent is evenly stressed, does not move, and does not twist.

Since the expanded diameter of the expansion body 13 on the delivery guide wire is slightly larger than the inner diameter of the target blood vessel, the expansion body 13 on the delivery guide wire is first set to a compressed deformation state, and the delivery guide wire The wire goes deep into the introduction sheath. At this time, the expansion body 13 becomes thinner and longer when the delivery guidewire is accommodated in the introduction sheath. When the sheath is released in the patient's blood vessel, the delivery guidewire The expansion body 13 will expand automatically, thereby becoming thicker and shorter.

By setting the expansion body 13 on the mandrel 11, the mandrel 11 located in the inner layer realizes the flexibility of the delivery guide wire and the function of super-selecting blood vessels; the expansion body of the outer layer 13 Realize uniform stress during the stent delivery process, while not affecting or minimizing the impact on the flexibility and super-selection performance of the delivery guide wire, and not affecting the release and recovery of the delivery guide wire in the blood vessel.

Further, in order to improve the effect of dilating blood vessels or to dilate blood vessels at multiple predetermined positions, as shown in FIG. The positions close to the distal end are arranged in sequence, and the plurality of expansion bodies 13 here can be arranged independently of each other or connected to each other.

As mentioned above, the expansion body 13 has the ability to expand outwards along the radial direction of the mandrel 11. For this reason, in some embodiments, the expansion body 13 can be made of nickel-titanium alloy-based material, for example. The structure of the metal cage, in the production process, can form multiple branches by cutting and heat-treating the pipe made of nickel-titanium alloy, and then weave the multiple branches into a network structure by splicing. , thus cooling and shaping into a cage structure. Here, the network structure of the expansion body 13 will not overlap with the braided wire of the stent inside the mandrel 11 .

In some other embodiments, the expansion body 13 may be a polymer elastomer with a hollow structure. The polymeric elastomer here is arranged as a single-layer porous structure, and several through holes are evenly distributed on the surface of the polymeric elastomer. Wherein, the polymer elastic body can present an ellipsoid-like structure in a natural expansion state, and in the state of being pressed by the outside world, the air or liquid inside it is evacuated to be in a compressed state, so that it can be worn It is retracted into the sheath to support the stent, and at the same time, the resistance of the stent to be pushed is increased due to the existence of friction.

In another embodiment, when the expansion body 13 adopts a structure such as a metal cage, it has interconnected branches 131, and a developing material 132 is arranged on the branches 131 of the expansion body 13, here The developing material 132 can be selected from at least one of platinum-iridium alloy, platinum-tungsten alloy, gold, and tantalum alloy; the shape of the developing material 132 can be at least one of sheet shape, wire shape, ring shape, etc.; Corresponding to the different shapes of the developing material, the mounting method of the developing material 132 on the branch 131 may be one of wire wrapping, pressing ring and inlaying.

In one embodiment, as shown in FIG. 5 , the shape of the developing material 132 can be set as a sheet. When the developing material 132 is in the form of a sheet, for example, the developing material 132 can be set in a mosaic manner, for example. On the branches of the expansion body 13, specifically, during manufacture, a hollow ring can be formed on the branches of the expansion body 13 by, for example, cutting, and the developing material, for example, in the form of a sheet 132 is embedded in this hollow ring, so that the developing material 132 in the form of a sheet with a slightly larger area can be stably fixed on the branches; The material 132 is arranged on the branches of the expansion body 13 .

In another embodiment, as shown in FIG. 6 , the developing material 132 may adopt a filamentary structure. For a filamentous structure, the developing material 132 may be installed in a wire-wrapped manner so that the developing material 132 It is fixed on the branch of the expansion body 13. During manufacture, a thin neck section is formed on the branch of the expansion body 13 by, for example, cutting, and the filamentous developing material 132 is placed on the branch. The thin neck section of the stem is wound into a spring shape, so that the developing material 132 can be installed on the branches; because in the structure of the metal cage, there are raised steps at both ends of each branch, Here, the step can limit the spring-shaped developing material 132 to prevent the developing material 132 from being displaced.

In another embodiment, as shown in FIG. 7 , the developing material 132 can adopt a ring-shaped structure, and for the ring-shaped structure, the developing material 132 can be installed in a ring-shaped manner so that the developing material 132 It is fixed on the branch of the expansion body 13. During production, a thin neck section is formed on the branch of the expansion body 13 by, for example, cutting, and the ring-shaped developing material 132 is sleeved on the branch. On the thin neck section of the branch and press it, so that the developing material 132 can be installed on the branch; because in the structure of the metal cage, there are raised steps at both ends of each branch Here, the step can limit the ring-shaped developing material 132 to prevent the developing material 132 from being displaced.

Generally, the distal end of the imaging section can be linear, which is suitable for tortuous blood vessels at the distal end of the aneurysm, or the special anatomical structure does not have a suitable position, as shown in Figure 3, in some embodiments, the imaging The distal end of the segment 2 is set in an arc structure, and the angle of the arc structure can be, for example, a 180° U-shaped structure or a J-shaped structure, so that the delivery guide wire in this embodiment is at the distal end of the patient's blood vessel. In the process of continuous delivery, even if a tortuous blood vessel or an obstacle is encountered, the blood vessel will not be punctured and cause the patient to bleed.

In addition, at least one protective body is arranged at the proximal end of the developing section 2, and the shape of the protective body is set as at least one of a sphere, an ellipsoid or a cone, and the material of the protective body is tin, UV glue, One of high molecular polymer and developable alloy materials.

In a preferred embodiment, as shown in FIG. 4, two protective bodies are provided at the proximal end of the developing section 2, which are respectively a first protective body 211 and a second protective body 212, wherein the first protective body here is A protective body 211 is set away from the crimping section 1, and the second protective body 212 is set close to the crimping section 1,

Wherein, the function of the first protective body 211 is that when the delivery guide wire is pushed or withdrawn in the blood vessel, when encountering a tortuous blood vessel, the diameter of the first protective body 211 is slightly larger than the delivery guide wire The outer diameter of the distal end can make the delivery guide wire not close to the blood vessel wall due to the diameter factor of the first protective body, so that it is not easy to get stuck in the blood vessel; the second protective body 212 here The function is to prevent the stent from being stuck or caught on the braided wire of the stent when the guide wire is retracted into the sheath tube when it rubs against the distal end of the stent, so as to prevent the stent from being driven during the recovery process, causing the stent to Displacement, or deformation of the distal port of the stent, or even shrinkage, causing vascular occlusion.

The second embodiment of the present disclosure provides a blood flow guiding device, which includes an introduction sheath, a stent, and the delivery guide wire in any one of the above-mentioned embodiments, and the delivery guide wire is set in the introduction sheath , the stent can be arranged in the delivery guidewire, especially in the mandrel 11 of the delivery guidewire.

The above description is only a preferred embodiment of the present disclosure and an illustration of the applied technical principles. Those skilled in the art should understand that the disclosure scope involved in this disclosure is not limited to the technical solution formed by the specific combination of the above-mentioned technical features, but also covers the technical solutions formed by the above-mentioned technical features or Other technical solutions formed by any combination of equivalent features. For example, a technical solution formed by replacing the above-mentioned features with (but not limited to) technical features with similar functions disclosed in this disclosure.

In addition, while operations are depicted in a particular order, this should not be understood as requiring that the operations be performed in the particular order shown or performed in sequential order. Under certain circumstances, multitasking and parallel processing may be advantageous. Likewise, while the above discussion contains several specific implementation details, these should not be construed as limitations on the scope of the disclosure. Certain features that are described in the context of separate embodiments can also be implemented in combination in a single embodiment. Conversely, various features that are described in the context of a single embodiment can also be implemented in multiple embodiments separately or in any suitable subcombination.

Although the subject matter has been described in language specific to structural features and/or methodological acts, it is to be understood that the subject matter defined in the appended claims is not necessarily limited to the specific features or acts described above. Rather, the specific features and acts described above are merely example forms of implementing the claims.

Multiple embodiments of the present disclosure have been described in detail above, but the present disclosure is not limited to these specific embodiments. Those skilled in the art can make various variations and modifications on the basis of the concept of the disclosure. These variations and modifications All should fall within the scope of protection claimed by the present disclosure.

Claims

A delivery guide wire, characterized in that it includes a continuously formed crimping section and a developing section, the crimping section includes a bendable mandrel, and at least one flexible The friction pad is provided with at least one expansion body near the distal end of the mandrel, the expansion body has the ability to self-expand outward along the radial direction of the mandrel, and the expansion body The end of the expansion body close to the friction pad is fixedly connected to the mandrel in the axial direction, and the end of the expansion body away from the friction pad is slidably connected to the mandrel in the axial direction, At least one protective body is arranged near the developing section.
The delivery guide wire according to claim 1, wherein the mandrel is a tubular structure with a fixed extension length or a telescopic tubular structure.
The delivery guide wire according to claim 1, wherein the friction pad is arranged on the mandrel, and its relative position with the mandrel in the axial direction is fixed, and the diameter of the mandrel 11 is Rotate upwardly about the mandrel or be fixed relative to the mandrel.
The delivery guide wire according to claim 3, characterized in that, the friction pad is fixed on the mandrel in a wrapping manner or a multi-turn coil spring is arranged around the mandrel, and the friction pad fixed on the coil spring.
The delivery guide wire according to claim 4, wherein the coil spring is made of platinum-iridium alloy.
The delivery guide wire according to claim 1, wherein when there are multiple friction pads, multiple friction pads are arranged on the mandrel in sequence.
The delivery guide wire according to claim 1, wherein the friction pad adopts at least one structure among cylinder, spindle and sphere.
The delivery guide wire according to claim 1, wherein the friction pad is made of polymer material.
The delivery guide wire according to claim 8, characterized in that, the polymer material is TPU material or silica gel material.
The delivery guide wire according to claim 1, characterized in that there are multiple expansion bodies, and the plurality of expansion bodies are arranged in sequence on the mandrel near its distal end.
The delivery guide wire according to claim 1, wherein the expansion body adopts a metal cage structure.
The delivery guide wire according to claim 1, characterized in that, the expansion body is a polymer elastomer with a hollow structure, and the polymer elastomer is configured as a single-layer porous structure.
The delivery guide wire according to claim 11, wherein when the expansion body adopts a metal cage structure, it has interconnected branches, and a developing material is arranged on the branches.
The delivery guide wire according to claim 13, wherein the imaging material is at least one of platinum-iridium alloy, platinum-tungsten alloy, gold, and tantalum alloy.
The delivery guide wire according to claim 13, wherein the shape of the developing material is at least one of sheet shape, wire shape and ring shape.
The delivery guide wire according to claim 15, characterized in that, according to the shape of the developing material, the installation method of the developing material on the branch adopts at least one of inlay, wire wrapping and looping.
The delivery guide wire according to claim 1, wherein the distal end of the developing section is arranged in an arc-shaped structure, and the arc-shaped structure is a U-shaped structure or a J-shaped structure.
The delivery guide wire according to claim 1, wherein the shape of the protective body is at least one of a sphere, an ellipsoid or a cone.
The delivery guide wire according to claim 18, characterized in that, the material of the protective body is one of tin, UV glue, high molecular polymer, and developable alloy material.
The delivery guide wire according to claim 1, wherein a first protective body and a second protective body are arranged at the proximal end of the developing section, the first protective body is arranged away from the crimping section, and the The second protection body is arranged close to the crimping section.
A blood flow guiding device, characterized in that it comprises an introduction sheath, a stent, and the delivery guidewire according to any one of the above claims, the delivery guidewire is set in the introduction sheath, and the stent can disposed within the delivery guidewire.