CN116413454A - Sample analyzer - Google Patents

Abstract

The application provides a sample analyzer, relates to medical instrument technical field. In practice, the casing comprises a bottom plate, a top plate, a first side plate and a second side plate; a first space is formed between the first partition plate and the first side plate, and a second space is formed between the first partition plate and the second side plate; the second partition board is positioned in the second space, a third space is formed between the second partition board and the top board, and a fourth space is formed between the second partition board and the bottom board; the reaction detection component is positioned in the first space and is adjacent to the bottom plate and the fourth space; the optical detection component is positioned in the third space and is adjacent to the reaction detection component. The partition board is used for dividing the space into a plurality of spaces, the reaction detection assembly is placed in the first space, the optical detection assembly is placed in the third space, the partition setting of each device in the sample analyzer is realized, the space can be effectively utilized, and the mutual influence between the devices can be reduced.

Description

Sample analyzer

Technical Field

The application relates to the technical field of medical instruments, in particular to a sample analyzer.

Background

With the wide application of sample analyzers, the functional requirements of diversification are also increased. Taking a blood cell analyzer as an example, most of the analyzers have complex structures, and unreasonable arrangement of internal devices, which causes space shortage inside the analyzers.

Disclosure of Invention

In one aspect, an embodiment of the present application provides a sample analyzer, including:

the shell comprises a bottom plate, a top plate, a first side plate and a second side plate, wherein the bottom plate and the top plate are oppositely arranged, the first side plate and the second side plate are oppositely arranged, the first side plate is respectively connected with the bottom plate and the top plate, and the second side plate is respectively connected with the bottom plate and the top plate;

a first partition plate disposed between the bottom plate and the top plate to form a first space between the first partition plate and the first side plate, and a second space between the first partition plate and the second side plate;

the second partition plate is positioned in the second space and is arranged between the first partition plate and the second side plate, a third space is formed between the second partition plate and the top plate, and a fourth space is formed between the second partition plate and the bottom plate;

the reaction detection assembly is positioned in the first space and is adjacent to the first partition plate and the fourth space; and

and the optical detection assembly is positioned in the third space and is adjacent to the reaction detection assembly.

The space in the casing is divided into a plurality of spaces through the first partition plate and the second partition plate, the reaction detection assembly is placed in the first space, the optical detection assembly is placed in the third space, the partition arrangement of each device in the sample analyzer is realized, the space can be effectively utilized, and each device is reasonably distributed in different spaces, so that the mutual influence between the devices is reduced.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic diagram of a sample analyzer according to an embodiment of the present application;

FIG. 2 is a partially exploded schematic illustration of the sample analyzer of FIG. 1;

FIG. 3 is a schematic view of a portion of the sample analyzer shown in FIG. 2;

FIG. 4 is a schematic view of the sample analyzer shown in FIG. 1 from another perspective;

FIG. 5 is a schematic view of the structure of the baffle plate assembly shown in FIG. 3;

FIG. 6 is a schematic view of a portion of the sample analyzer shown in FIG. 3;

FIG. 7 is a schematic view of the fourth separator plate shown in FIG. 3 mated with a fifth separator plate and a flow path system;

FIG. 8 is a schematic view of a portion of the sample analyzer shown in FIG. 3;

FIG. 9 is a schematic diagram of the flow path system, fourth baffle, and fifth baffle cooperation in the embodiment shown in FIG. 8.

Detailed Description

The present application is described in further detail below with reference to the drawings and examples. It is specifically noted that the following examples are only for illustration of the present application, but do not limit the scope of the present application. Likewise, the following embodiments are only some, but not all, of the embodiments of the present application, and all other embodiments obtained by a person of ordinary skill in the art without making any inventive effort are within the scope of the present application.

Reference in the specification to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments.

The present application describes a sample analyzer. The sample analyzer can be used for analyzing data of biological samples such as blood, urine and the like. Referring to fig. 1 and 2, fig. 1 is a schematic structural diagram of a sample analyzer according to an embodiment of the present application, and fig. 2 is a partially exploded schematic diagram of the sample analyzer shown in fig. 1. The sample analyzer 100 may include a sample placement stage 101 for placing a sample and an apparatus body 102 mounted with the sample placement stage 101 and for detecting the sample. Wherein the sample placement station 101 may be used to place samples collected by a user. The sample placing stage 101 may be mounted on the apparatus main body 102 so that the apparatus main body 102 samples and detects a sample on the sample placing stage 101. In some embodiments, the sample station 101 may be omitted. The device body 102 may perform detection and data analysis on the sample to generate a detection result.

Referring to fig. 2 and 3, fig. 3 is a schematic diagram illustrating a portion of the sample analyzer 100 shown in fig. 2. The apparatus body 102 may include a cabinet 10 mounted with the sample stage 101 and having a receiving space, a display apparatus 20 mounted on the cabinet 10, a partition plate assembly 30 mounted in the cabinet 10 to divide the receiving space into a plurality of spaces, a reaction detecting assembly 40 mounted in the cabinet 10 and used for processing a sample, a sample transferring assembly 50 mounted in the cabinet 10 and used for transferring the sample into the reaction detecting assembly 40, an optical detecting assembly 60 mounted in the cabinet 10 and used for optically detecting the sample processed in the reaction detecting assembly 40, a circuit board assembly 70 mounted in the cabinet 10 and used for controlling the normal operation of the apparatus body 102, and a flow path system mounted in the cabinet 10 and used for realizing the transfer of the sample and/or reagent among the reaction detecting assembly 40, the sample transferring assembly 50, and the optical detecting assembly 60.

The casing 10 is used for protecting each device in the device main body 102, and may also be used for dividing each device from the outside, so as to avoid interference from the outside. The display device 20 is used for inputting control instructions to the circuit board assembly 70, and may also be used for displaying operation data and detection results of the device main body 102. The partition board assembly 30 is used for dividing the accommodating space in the casing 10 into a plurality of spaces, realizing the space division setting of each device, and further creating the environment of dry-wet separation and liquid-electricity separation. The reaction detection component 40 is used to process a sample with a reagent. The sample transfer assembly 50 can be configured to transfer samples in conjunction with a flow system to inject the samples into the optical detection assembly 60. The optical detection assembly 60 is used for optically detecting the sample after the reagent treatment. The circuit board assembly 70 may be electrically connected to devices within the apparatus body 102, such as the reaction detection assembly 40, the sample transfer assembly 50, the optical detection assembly 60, the flow system, etc., to enable the apparatus body 102, such as the reaction detection assembly 40, the sample transfer assembly 50, the optical detection assembly 60, the flow system, etc., to operate properly. The flow path system may be used for sample pipetting, for injecting a reagent-treated sample into the optical detection module 60, and for discharging waste liquid from the apparatus body 102 such as the reaction detection module 40 and the optical detection module 60.

It will be appreciated that in the description of the present application, it is to be noted that the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected, unless otherwise specifically defined and limited; the connection can be mechanical connection, electrical connection, pipeline, liquid circuit and the like; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the terms herein above will be understood to those of ordinary skill in the art in a specific context.

Referring to fig. 1 and 2, the casing 10 may be made of a rigid material. The cabinet 10 may include a main housing 11 mounted with the setting table 101 and provided with a receiving space, and a sub-housing 12 mounted on a side of the main housing 11 facing the setting table 101. The sub-housing 12 is used for shielding a portion of the main housing 11 facing the sample placement table 101, so as to prevent devices in the main housing 11 from being exposed, and improve the appearance expressive force of the sample analyzer 100.

Referring to fig. 1, 2 and 4, fig. 4 is a schematic structural diagram of the sample analyzer 100 shown in fig. 1 at another view angle. The main housing 11 may include a bottom plate 111 and a top plate 112 disposed opposite to each other, a first side plate 113 and a second side plate 114 disposed opposite to each other, and a third side plate 115 and a fourth side plate 116 disposed opposite to each other. The first side plate 113 may be connected to the bottom plate 111 and/or the bottom plate 111, the second side plate 113 may be connected to the bottom plate 111 and/or the bottom plate 111, the third side plate 115 may be connected to the bottom plate 111 and/or the first side plate 113 and/or the second side plate 114, and the fourth side plate 116 may be connected to the bottom plate 111 and/or the first side plate 113 and/or the second side plate 114. Namely, the bottom plate 111, the top plate 112, the first side plate 113, the second side plate 114, the third side plate 115, and the fourth side plate 116 enclose a housing space.

It should be noted that the terms "first," "second," … … and the like herein and in the context are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, features defining "first", "second", … …, etc., can explicitly or implicitly include one or more of such features.

It will be appreciated that the designations of "first side panel", "second side panel", "third side panel", "fourth side panel", and "side panel" may be interchanged, for example, in some embodiments, the "first side panel" may be referred to as "second side panel" and the "second side panel" may be referred to as "first side panel".

In some embodiments, the base plate 111 may be secured to the docking station 101 by, for example, welding, snap-fit, plugging, screwing, or the like.

In some embodiments, the top plate 112 is disposed opposite the bottom plate 111 to form a receiving space between the top plate 112 and the bottom plate 111.

In some embodiments, the first side plate 113 may be connected and fixed to the bottom plate 111 and the top plate 112, respectively, for example, by welding, snap-fit connection, plugging, screwing, or the like. In some embodiments, the first side plate 113 may be detachably connected to the bottom plate 111 and the top plate 112, respectively, so that the device body 102 may be detached at any time for maintenance. In some embodiments, the first side panel 113 may be integrally formed with at least one of the bottom panel 111 and the top panel 112. In some embodiments, the first side plate 113 may be located on the same side of the bottom plate 111 and the top plate 112.

In some embodiments, the portion of the first side plate 113 near the side of the sample placement table 101 may be fixedly connected to the sample placement table 101, for example, by welding, snap-in connection, plugging, screwing, or the like. Of course, it is also possible to fix only the contact or the interval arrangement without connection.

In some embodiments, the second side plate 114 may be disposed opposite to the first side plate 113 to form a receiving space between the first side plate 113 and the second side plate 114. In some embodiments, the second side plate 114 may be connected and fixed to the bottom plate 111 and the top plate 112, respectively, for example, by welding, snap-fit connection, plugging, screwing, or the like. In some embodiments, the second side plate 114 may be detachably connected to the bottom plate 111 and the top plate 112, respectively, so that the device body 102 may be detached at any time for maintenance. In some embodiments, the second side panel 114 may be of unitary construction with at least one of the bottom panel 111 and the top panel 112. In some embodiments, the second side panel 114 may be located on the same side of the bottom panel 111 and the top panel 112.

In some embodiments, the portion of the second side plate 114 near the side of the sample placement table 101 may be fixedly connected to the sample placement table 101, for example, by welding, snap-in connection, plugging, screwing, or the like. Of course, it is also possible to fix only the contact or the interval arrangement without connection.

In some embodiments, the second side panel 114 is provided with a first opening 1141 proximate a side of the bottom panel 111. That is, the first opening 1141 is disposed adjacent to the bottom plate 111. Of course, the first opening 1141 may be disposed at any position on the second side plate 114, which will not be described herein. The first opening 1141 communicates with the accommodating space. In some embodiments, the second side plate 114 provides a first maintenance door 1142 at the first opening 1141. To facilitate maintenance by the first door 1142 and to avoid the expansion of maintenance work caused by removing the second side plate 114 instead of the first door 1142. In some embodiments, a vent hole is provided in the first door 1142 that communicates with the receiving space.

In some embodiments, the third side panel 115 is disposed on a side of the bottom panel 111 remote from the sample station 101. The third side plate 115 may be connected and fixed with the bottom plate 111, the top plate 112, the first side plate 113 and the second side plate 114, for example, by welding, fastening, plugging, screwing, etc. In some embodiments, the third side plate 115 may be detachably connected to the bottom plate 111, the top plate 112, the first side plate 113, and the second side plate 114, respectively, so as to be detachable at any time, and to perform maintenance on the apparatus main body 102. In some embodiments, the third side panel 115 may be integrally constructed with at least one of the bottom panel 111, the top panel 112, the first side panel 113, and the second side panel 114. In some embodiments, the third side panel 115 may be located on the same side as the bottom panel 111, the top panel 112, the first side panel 113, and the second side panel 114.

In some embodiments, the third side panel 115 is provided with a second opening 1151 adjacent to a side of the first side panel 113. That is, the second opening is disposed adjacent to the first side plate 113. Of course, the second opening 1151 may also be disposed at any position of the third side plate 115, which will not be described herein. The second opening 1151 communicates with the accommodating space. In some embodiments, the third side plate 115 provides a second maintenance door 1152 at the second opening 1151. To perform simple maintenance through the second maintenance door 1152, avoiding the expansion of maintenance work caused by the replacement of the second maintenance door 1152 by the disassembly of the third side plate 115.

In some embodiments, the fourth side plate 116 is disposed on a side of the third side plate 115 that is adjacent to the docking station 101. The fourth side plate 116 is disposed opposite to the third side plate 115 to form a receiving space between the third side plate 115 and the fourth side plate 116. In some embodiments, the fourth side plate 116 may be connected and fixed to the bottom plate 111, the top plate 112, the first side plate 113, and the second side plate 114, for example, by welding, snap-fit connection, plugging, screwing, or the like. In some embodiments, the fourth side plate 116 may be detachably connected to the bottom plate 111, the top plate 112, the first side plate 113, and the second side plate 114, respectively, so as to be detachable at any time, and to perform maintenance on the apparatus main body 102. In some embodiments, the fourth side panel 116 may be integrally constructed with at least one of the bottom panel 111, the top panel 112, the first side panel 113, and the second side panel 114. In some embodiments, the fourth side panel 116 may be located on the same side of the bottom panel 111, the top panel 112, the first side panel 113, and the second side panel 114.

In some embodiments, the fourth side plate 116 may be fixedly connected to the sample placement stage 101, such as by welding, snap-fit connection, plugging, screwing, or the like. Of course, it is also possible to fix only the contact or the interval arrangement without connection.

In some embodiments, the fourth side panel 116 is provided with a third opening 1161 adjacent to a side of the bottom panel 111. I.e., third opening 1161 is disposed adjacent to bottom plate 111.

It should be understood that the connection relationship among the bottom plate 111, the top plate 112, the first side plate 113, the second side plate 114 and the fourth side plate 116 in the main housing 11 is not limited thereto, and may be arranged in other manners, and is not limited thereto.

Referring to fig. 1 and 2, the sub-housing 12 may be disposed on a side of the main housing 11 facing the sample stage 101. The sub-housing 12 may be disposed opposite the fourth side plate 116 to form a sample space between the sub-housing 12 and the fourth side plate 116. In some embodiments, the sub-housing 12 may be fixedly connected with at least one of the top plate 112, the first side plate 113, the second side plate 114, the fourth side plate 116, and the sample placement stage 101, for example, by welding, snap-in connection, plugging, screwing, or the like. Of course, other manners of connection and fixation between the sub-housing 12 and the main housing 11 may be adopted.

Referring to fig. 1 and 2, the display device 20 may be embedded in the sub-housing 12. The display device 20 may be disposed on a side of the sub-housing 12 away from the main housing 11, so that a user may operate the sample analyzer 100, for example, to control the operation of the sample analyzer 100, and may also operate the taking, placing and moving of the sample on the sample placing table 101. In some embodiments, display device 20 may act as an output device to output operational data and detection data of sample analyzer 100. In some embodiments, display device 20 may act as an input device to input control instructions that control the operation of sample analyzer 100. It will be appreciated that other output devices, such as printers, etc., may be substituted for display device 20 as an output device. When the display device 20 is used as an input device, other output devices such as a keyboard, a code scanning device, etc. may be substituted.

Referring to fig. 3 and 5, fig. 5 is a schematic view of the separator assembly 30 shown in fig. 3. The diaphragm assembly 30 may be made of a rigid material, but may be made of the same material as the casing 10. The partition assembly 30 may include a first partition 31 disposed between the bottom plate 111 and the top plate 112 and disposed opposite the first and second side plates 113 and 114, respectively, a second partition 32 and a third partition 33 disposed between the first and second side plates 31 and 114 and disposed opposite the bottom plate 111 and 112, respectively, a fourth partition 34 disposed between the first partition 31 and the first side plate 113 and disposed opposite the bottom plate 111 and the top plate 112, respectively, and a fifth partition 35 disposed between the bottom plate 111 and the fourth partition 34 and disposed opposite the first and first side plates 113 and 31, respectively.

It will be appreciated that the designations of "first separator", "second separator", "third separator", "fourth separator", "fifth separator", and "separator" may be interchanged, for example, in some embodiments, the "first separator" may be referred to as "second separator" and the "second separator" may be referred to as "first separator".

Referring to fig. 3, 5 and 6, fig. 6 is a schematic view of a portion of the sample analyzer 100 shown in fig. 3. The first partition 31 may be connected and fixed to the bottom plate 111, the third side plate 115, and the fourth side plate 116, for example, by welding, snap-in connection, plugging, screwing, etc. It is understood that the first partition 31 may be fixedly connected to at least one of the bottom plate 111, the top plate 112, the third side plate 115, and the fourth side plate 116.

The first partition 31 may divide the receiving space into two spaces, for example, a first space 301 between the first partition 31 and the second side plate 114 and a second space 302 between the first partition 31 and the first side plate 113.

The second partition 32 may be connected and fixed to the first partition 31, the third side plate 115, and the fourth side plate 116, for example, by welding, snap-in connection, plugging, screwing, or the like. It is understood that the second partition 32 may be fixedly connected to at least one of the first partition 31, the second side plate 114, the third side plate 115, and the fourth side plate 116.

The second partition 32 may divide the first space 301 into two spaces, for example, a third space 3011 between the second partition 32 and the bottom plate 111 and a fourth space 3012 between the second partition 32 and the top plate 112. The second partition 32 is provided to separate the third space 3011 from the fourth space 3012. In some embodiments, the second separator 32 can be omitted.

In some embodiments, the third space 3011 is disposed adjacent to and in communication with the first opening 1141 (fig. 2).

The third partition 33 may be connected and fixed to the third side plate 115 and the fourth side plate 116, for example, by welding, snap-fit connection, plugging, screwing, etc. It is understood that the third partition 33 may be fixedly connected to at least one of the first partition 31, the second side plate 114, the third side plate 115, and the fourth side plate 116.

The third partition 33 may divide the fourth space 3012 into two spaces, for example, a fifth space 3013 between the third partition 33 and the second partition 32 and a sixth space 3014 between the third partition 33 and the top plate 112. In some embodiments, the third separator 33 can be omitted.

The fourth partition 34 may be connected and fixed to the first partition 31, the third side plate 115, and the fourth side plate 116, for example, by welding, snap-fit connection, plugging, screwing, or the like. It is understood that the fourth separator 34 may be fixedly connected to at least one of the first separator 31, the first side plate 113, the third side plate 115, and the fourth side plate 116.

The fourth partition 34 may divide the second space 302 into two spaces, for example, a seventh space 3021 between the fourth partition 34 and the bottom plate 111 and an eighth space 3022 between the second partition 32 and the top plate 112.

The fourth partition 34 is provided so that the seventh space 3021 is separated from the eighth space 3022.

The fifth partition 35 may be connected and fixed to the bottom plate 111, the fourth partition 34, the third side plate 115, and the fourth side plate 116, for example, by welding, fastening, plugging, screwing, etc. It will be appreciated that the fifth spacer 35 may be fixedly coupled to at least one of the bottom panel 111, the fourth spacer 34, the third side panel 115, and the fourth side panel 116.

The fifth partition 35 may divide the seventh space 3021 into two spaces, for example, a ninth space 3023 between the fourth partition 34 and the first side plate 113 and a tenth space 3024 between the fourth partition 34 and the first partition 31.

The fifth partition 35 is provided so as to separate the ninth space 3023 from the tenth space 3024.

It will be appreciated that the designations of "first space", "second space", "third space", "fourth space", "fifth space", "sixth space", "seventh space", "eighth space", "ninth space", "tenth space", and "space" may be switched between each other, for example, in some embodiments, the "first space" may be referred to as "second space" and the "second space" may be referred to as "first space".

In some embodiments, tenth space 3024 is disposed adjacent to and in communication with second opening 1151 (fig. 4).

Referring to fig. 5 and 7, fig. 7 is a schematic view showing the configuration of the fourth partition 34 and the fifth partition 35 shown in fig. 3, and the flow path system. The fifth partition 35 is provided with a fourth opening 351 on a side near the fourth side plate 116. That is, the fourth opening 351 is disposed adjacent to the fourth side plate 116. The fourth opening 351 may communicate the ninth space 3023 with the tenth space 3024.

It will be appreciated that the designations of "first opening", "second opening", "third opening", "fourth opening", and "opening" may be interchanged, for example, in some embodiments, the "first opening" may be referred to as "second opening" and the "second opening" may be referred to as "first opening".

The fifth partition 35 is provided with a movable portion 352 at the fourth opening 351 for blocking the fourth opening 351. In some embodiments, the movable portion 352 may flip into the ninth space 3023. In some embodiments, the movable portion 352 may be omitted. In some embodiments, the movable portion 352 is of unitary construction with the fifth diaphragm 35.

Referring to fig. 3, a reaction detection assembly 40 may be installed in the third space 3011. In some embodiments, the reaction detection assembly 40 may be mounted on at least one of the base plate 111 and the first separator plate 31, such as by welding, snap-fit connection, plugging, screwing, or the like. The reaction detection component 40 may include a blood routine measurement component. In some embodiments, the blood routine measurement assembly includes a RET reaction cell assembly, a WBC reaction cell assembly, and an HGB reaction cell assembly. The reaction detection component 40 can process the sample with a reagent so that the processed sample can be detected.

In one embodiment, the reaction detection assembly 40 may be disposed adjacent the first opening 1141 for easy maintenance through the first opening 1141 for ventilation through the first maintenance door 1142.

In one embodiment, the reaction detection component 40 is disposed opposite the third opening 1161 for sample pipetting into the reaction detection component 40.

Referring to fig. 3, a sample transfer assembly 50 may be installed in the third space 3011. In some embodiments, the sample transfer assembly 50 is mounted on the first separator plate 31, such as by welding, snap-fit connection, plugging, screwing, or the like. The pipetting assembly 50 is positioned above the reaction detection assembly 40 such that the pipetting assembly 50 pipettes samples into the reaction detection assembly 40.

The sample transfer assembly 50 may include a cross member 51 mounted on the first separator 31 and a sampling assembly 52 slidably coupled to the cross member 51.

Wherein the cross beam 51 may be disposed above the reaction detection assembly 40. One end of the cross member 51 in the extending direction may be located in the third space 3011, and the other end may protrude from the accommodating space at the third opening 1161 to protrude into the sample accommodating space between the main casing 11, for example, the fourth side plate 116 and the sub-casing 12.

In some embodiments, the beam 51 may also be directly disposed on the second partition 32, which is not described herein.

The sampling assembly 52 is slidably connected to the cross member 51 so as to slide in the extending direction of the cross member 51. In some embodiments, the sampling assembly 52 may be driven by a drive to slide on the cross beam 51.

The sampling assembly 52 may include a sampling needle that may be used to aspirate a sample. The sampling assembly 52 is slidable on the cross member 51 into the sample placement space between the main housing 11, e.g., the fourth side plate 116, and the sub-housing 12 to sample and pipette the sample placed in the sample placement space, and slidable on the cross member 51 to slide over the reaction detection assembly 40 to inject the sample into the reaction detection assembly 40.

Referring to fig. 3, 6 and 8, fig. 8 is a schematic diagram of a portion of the sample analyzer 100 shown in fig. 3. The optical detection assembly 60 is used to detect the sample that has been subjected to the reagent processing in the reaction detection assembly 40. The optical detection element 60 may be disposed in the eighth space 3022 and connected to the reaction detection element 40 and disposed adjacent thereto, so as to reduce the distance between the reaction detection element 40 and the optical detection element 60, for example, the distance between the reaction detection element 40 and the optical detection element 60, and facilitate cleaning. In some embodiments, the optical detection assembly 60 may be mounted on at least one of the first and fourth baffles 31, 34, such as by welding, snap-fit connection, plugging, screwing, or the like. The optical detection assembly 60 and the reaction detection assembly 40 are respectively arranged in different spaces to realize dry-wet separation.

Referring to fig. 3, the circuit board assembly 70 may be electrically connected to the display device 20, the reaction detecting assembly 40, the sample moving assembly 50, and the optical detecting assembly 60 to drive each device to operate, and may obtain the detection data of the reaction detecting assembly 40 and the optical detecting assembly 60. The circuit board assembly 70 may include a main control board assembly, a driving board assembly, a temperature control board assembly, a signal board assembly, etc. The main control board assembly can be electrically connected with the driving board assembly, the temperature control board assembly and the signal board assembly respectively. The main control board assembly can comprehensively control the normal operation of the driving board assembly, the temperature control board assembly and the signal board assembly. The driving board assembly can be used for controlling a flow path system, the signal board assembly can be used for acquiring detection data of the reaction detection assembly 40 and the optical detection assembly 60 and transmitting control data and operation data of the reaction detection assembly 40 and the optical detection assembly 60, and the temperature control board assembly can be used for detecting temperature change conditions in a space.

In some embodiments, the circuit board assembly 70 may be divided into two parts electrically connected to each other, namely a first main board 71 mounted on the second partition 32 and a second main board 72 mounted on the third partition 33. The first main board 71 is disposed in the fifth space 3013. The second main board 72 is disposed in the sixth space 3014. Of course, in some embodiments, the temperature control plate assembly may be disposed within the third space 3011 and/or the seventh space 3021 and/or the eighth space 3022 instead of being a part of the first main plate 71 and/or the second main plate 72 to perform temperature monitoring of the respective spaces. It will be appreciated that the circuit board assembly 70 is disposed in the fourth space 3012 and may have a liquid-electric separation effect from the third space 3011.

A flow path system may be used to effect transport of samples and/or reagents between reaction detection component 40, sample transfer component 50, and optical detection component 60.

Referring to fig. 4, the flow path system may include a reagent interface 801. In some embodiments, the reagent interface 801 may be provided on the third side plate 115, for example, by welding, snap-fit connection, plugging, screwing, or the like. Of course, the cover may be disposed on other side plates or the bottom plate 111 as needed, and will not be described in detail. In some embodiments, the reagent interface 801 may extend into the ninth space 3023. In some embodiments, reagent interface 801 may be disposed proximate to one side of base plate 111. That is, the reagent interface 801 is disposed adjacent to the bottom plate 111.

The reagent interface 801 is used to connect with a container containing a reagent, such as a reagent pack, etc., so that the reagent flows from the reagent interface 801 into the sample analyzer 100. It is understood that the reagents may have at least one type, and the number of specific types may be normally configured according to the requirements of the reaction detecting component 40, which will not be described in detail.

Referring to fig. 7 and 8, the flow path system may include a fluid level and gas source detection assembly 802. In some embodiments, the liquid level and gas source detection assembly 802 may be disposed in the ninth space 3023 and on the fifth bulkhead 35, such as by welding, snap-fit connection, plugging, screwing, etc. In some embodiments, a liquid level and gas source detection assembly 802 is disposed adjacent to the reagent interface 801. In some embodiments, the liquid level and gas source detection assembly 802 is disposed adjacent to the third side plate 115. In some embodiments, the liquid level and gas source detection assembly 802 is further from the base plate 111 than the reagent interface 801.

The liquid level and air source detection component 802 is used for detecting the liquid level of the reagent in the liquid path connected with the reagent interface 801, and guaranteeing the normal supply of the reagent. The liquid level and air source detection assembly 802 is arranged at a position which can facilitate the reagent to flow from a low position to a high position in a liquid path connected with the reagent interface 801, so that the detection result of the liquid level in the liquid path by the liquid level and air source detection assembly 802 is more accurate. In some embodiments, the liquid level and gas source detection assembly 802 may be omitted.

Referring to fig. 8, the flow path system may include a syringe assembly 803. In some embodiments, the syringe assembly 803 may be disposed on the fifth baffle 35, such as by welding, snap-fit, plugging, screwing, etc., so that maintenance of the syringe assembly 803 may be performed by removing the first side plate 113. In some embodiments, the injector assembly 803 may be disposed on a side of the liquid level and gas source detection assembly 802 that is adjacent to the fourth side plate 116. In some embodiments, the syringe assembly 803 may be disposed below the movable portion 352. That is, injector assembly 803 is closer to base plate 111 than movable portion 352.

The syringe assembly 803 may be used for extraction and injection of reagents, samples, etc. The injector assembly 803 may include a plurality of injection devices such that each injection device is coupled to a valve assembly in the flow system to control the flow system. In some embodiments, the portion of the injector assembly 803, e.g., the injection device, within the ninth space 3023 may be coupled to a sampling needle of a sample transfer assembly 50, e.g., the sampling assembly 52, to enable sampling for the sample extraction and to enable the sampling needle to inject the sample into a reaction detection assembly 40, e.g., a blood routine measurement assembly.

Referring to fig. 7, 8 and 9, fig. 9 is a schematic view of the configuration of the flow path system, the fourth partition 34 and the fifth partition 35 in the embodiment shown in fig. 8. The flow path system may include a first valve assembly 804. The first valve assembly 804 may be disposed on the fifth diaphragm 35, e.g., the movable portion 352, mounted, e.g., by welding, snap-fit connection, plugging, screwing, etc., to be fully flipped into the ninth space 3023 when the movable portion 352 is flipped into the ninth space 3023, so that maintenance of the first valve assembly 804 may be performed by removing the first side plate 113.

The first valve assembly 804 may include a plurality of liquid valves. In some embodiments, a first valve assembly 804, such as a liquid valve, is coupled to the syringe assembly 803 in the ninth space 3023 and is connectable to the reaction detection assembly 40 in the tenth space 3024. A first valve assembly 804, such as a liquid valve, cooperates with the syringe assembly 803 to inject reagents withdrawn by the syringe assembly 803 into a reaction detection assembly 40, such as a blood routine measurement assembly.

Referring to fig. 9, the flow path system may include a second valve assembly 805. In some embodiments, the second valve assembly 805 is disposed on the fifth bulkhead 35 and within the ninth space 3023, such as by welding, snap-fit connection, plugging, screwing, etc., so that maintenance of the second valve assembly 805 may be performed by removing the first side plate 113. In some embodiments, the second valve assembly 805 is located on a side of the first valve assembly 804 remote from the fourth side plate 116. In some embodiments, the second valve assembly 805 is located above the syringe assembly 803. In some embodiments, the second valve assembly 805 is located above the liquid level and gas source detection assembly 802.

The second valve assembly 805 may include at least one gas valve and at least one liquid valve. A second valve assembly 805, such as a liquid valve, may be coupled to the reagent interface 801 such that the liquid level and gas source detection assembly 802 performs liquid level detection of a liquid path connecting the second valve assembly 805, such as the liquid valve, to the reagent interface 801.

A second valve assembly 805, such as a liquid valve, may be coupled to a portion of the syringe assembly 803, such as an injection device, within the ninth space 3023 to mate with the syringe assembly 803, such as an injection device, to withdraw reagent from the reagent interface 801 for further injection into the reaction detection assembly 40 under the mating of the syringe assembly 803, such as an injection device, with the first valve assembly 804, such as a liquid valve.

Referring to fig. 6 and 9, the flow path system may include a third valve assembly 806. In some embodiments, third valve assembly 806 may be disposed within ninth space 3023 to provide for maintenance of second valve assembly 805 by removing first side panel 113. Of course, it may be disposed in the tenth space 3024. In some embodiments, a third valve assembly 806 may be disposed above the syringe assembly 803. In some embodiments, third valve assembly 806 is disposed adjacent to reaction detection assembly 40, optical detection assembly 60, respectively. In some embodiments, the third valve assembly 806 may be disposed on one of the fourth bulkhead 34, the fifth bulkhead 35, the fourth side plate 116, such as by welding, snap-fit connection, plugging, screwing, etc. In some embodiments, the third valve assembly 806 may be disposed on a side of the first valve assembly 804 proximate to the fourth side plate 116.

The third valve assembly 806 may include at least one liquid valve. A third valve assembly 806, such as a liquid valve, may connect the portion of the syringe assembly 803, such as the injection device, within the ninth space 3023, the reaction detection assembly 40, and the optical detection assembly 60 such that the third valve assembly 806, such as a liquid valve, mates with the syringe assembly 803, such as the injection device, such that the syringe assembly 803, such as the injection device, draws the reagent-treated sample from the reaction detection assembly 40 and injects the reagent-treated sample into the optical detection assembly 60.

Referring to fig. 8 and 9, the flow path system may include an air pump assembly 807. In some embodiments, the air pump assembly 807 is located in the tenth space 3024 and is disposed on the fifth diaphragm 35, such as by welding, snap-fit connection, plugging, screwing, or the like. In some embodiments, the air pump assembly 807 is disposed adjacent to the second valve assembly 805. In some embodiments, the air pump assembly 807 is disposed adjacent to the second opening 1151 for maintenance through the second opening 1151.

The air pump assembly 807 is used to support the air passages in the flow path system. The air pump assembly 807 may be adapted to be coupled to a second valve assembly 805, such as a gas valve, to effect delivery of air within the air pump assembly 807 in cooperation with the second valve assembly 805, such as a gas valve, and a syringe assembly 803, such as an injection device or relay, or the like.

Referring to fig. 8 and 9, the flow path system may include a plenum assembly 808. In some embodiments, the plenum assembly 808 is located within the tenth space 3024 and mounted to the fifth bulkhead 35, such as by welding, snap-fit connection, plugging, screwing, or the like. In some embodiments, the air pressure chamber assembly 808 is located below the air pump assembly 807. In some embodiments, the plenum assembly 808 is disposed adjacent to the liquid level and gas source detection assembly 802. In some embodiments, the plenum assembly 808 is disposed adjacent to the second opening 1151 for maintenance through the second opening 1151.

The air pressure chamber assembly 808 is connected to a second valve assembly 805 such as an air valve, so that the air pump assembly 807 performs air delivery with the cooperation of the second valve assembly 805 such as an air valve and the injector assembly 803 such as an injection device or a relay, etc., so that the air pressure chamber assembly 808 generates negative pressure. The air pressure chamber assembly 808 is coupled to the liquid level and air source detection assembly 802 such that the liquid level and air source detection assembly 802 detects the negative pressure of the air pressure chamber assembly 808.

Referring to fig. 6 and 9, the flow system may include a filter assembly 809. In some embodiments, filter assembly 809 is located within tenth space 3024 and mounted to first bulkhead 31, such as by welding, snap-fit connection, plugging, screwing, or the like. In some embodiments, the filter assembly 809 is disposed adjacent to the plenum assembly 808. In some embodiments, the filter assembly 809 is disposed adjacent to the second opening 1151 for maintenance through the second opening 1151.

The filter assembly 809 is connected to the reaction detecting assembly 40 and the optical detecting assembly 60, respectively, so as to filter the waste liquid in the reaction detecting assembly 40 and the optical detecting assembly 60, and reduce the influence on the flow path system. In some embodiments, the filter component 809 may be omitted.

Referring to fig. 3, 6 and 9, the flow path system may include a fourth valve assembly 810. In some embodiments, fourth valve assembly 810 is located within third space 3011 and tenth space 3024 and is mounted to first barrier 31, such as by welding, snap-fit connection, plugging, screwing, or the like. In some embodiments, the fourth valve assembly 810 is disposed adjacent to the pneumatic chamber assembly 808. In some embodiments, the fourth valve assembly 810 is disposed adjacent to the first opening 1141 and/or the second opening 1151 for maintenance through the first opening 1141 and/or the second opening 1151. In some embodiments, the fourth valve assembly 810 is located below the filter assembly 809.

It will be appreciated that the designations of "first valve assembly", "second valve assembly", "third valve assembly", "fourth valve assembly", and "valve assembly" may be interchanged, for example, in some embodiments, the "first valve assembly" may be referred to as "second valve assembly" and the "second valve assembly" may be referred to as "first valve assembly".

The fourth valve assembly 810 may include a plurality of liquid valves. A fourth valve assembly 810, such as a liquid valve, is connected to the filter assembly 809 and the air pressure chamber assembly 808 in the tenth space 3024 to draw out the waste liquid in the reaction detecting assembly 40 and the optical detecting assembly 60 in the case where the air pressure chamber assembly 808 generates negative pressure. A fourth valve assembly 810, such as a liquid valve, can drain the waste liquid drawn by the plenum assembly 808 within the third space 3011.

Referring to fig. 3, 6 and 9, the flow system may include a liquid pump assembly 811. In some embodiments, the liquid pump assembly 811 may be located within the third space 3011 and mounted to the base plate 111, such as by welding, snap-fit connection, plugging, screwing, or the like. In some embodiments, the liquid pump assembly 811 is disposed adjacent to the fourth valve assembly 810. In some embodiments, the liquid pump assembly 811 is disposed adjacent to the third side plate 115. In some embodiments, the liquid pump assembly 811 is disposed adjacent to the first opening 1141 for maintenance through the first opening 1141.

The liquid pump assembly 811 is connected to a fourth valve assembly 810, such as a liquid valve, such that the liquid pump assembly 811 draws waste liquid from the pneumatic chamber assembly 808 through the fourth valve assembly 810.

Referring to fig. 3 and 4, the flow path system can include a waste interface 812. In some embodiments, waste interface 812 may be located within third space 3011 and mounted to third side plate 115, such as by welding, snap-fit connection, plugging, screwing, or the like. It will be appreciated that waste interface 812 may also be provided on other side or bottom panels 111.

In some embodiments, waste interface 812 is disposed adjacent to liquid pump assembly 811. In some embodiments, waste interface 812 is disposed adjacent to bottom plate 111. In some embodiments, waste interface 812 is disposed adjacent to first opening 1141 for maintenance through first opening 1141.

The waste liquid port 812 is connected to the liquid pump assembly 811 to discharge waste liquid pumped by the liquid pump assembly 811.

The accommodating space in the casing 10 is divided into a plurality of spaces through the partition plate assembly 30, the space division setting of each device is realized, and then the environment of dry-wet separation and liquid-electricity separation is created. The flow path system is provided on the fifth separator 35. Maintenance can be facilitated. The arrangement of the flow path system in the accommodating space can facilitate the simplicity of the liquid path and the gas path, and can facilitate the maintenance of the flow path system. For example, the valve components are distributed to the positions close to the communicated devices, so that the space utilization rate is improved, and the liquid paths and gas paths connected with each other can be relatively shortened.

In addition, the circuit board assembly 70 is separated from other components in other spaces by the second separator 32 and the third separator 33 to prevent damage caused by other conditions such as leakage, so that the damage risk of the circuit board assembly 70 is reduced, and the sample moving assembly 50 can directly transport samples into the reaction detecting assembly 40, thereby improving the efficiency.

The sample analyzer 100 has reasonable structural layout and compact layout of each part, and can relatively reduce the volume of the sample analyzer 100.

Claims (17)

1. A sample analyzer, comprising:

the shell comprises a bottom plate, a top plate, a first side plate and a second side plate, wherein the bottom plate and the top plate are oppositely arranged, the first side plate and the second side plate are oppositely arranged, the first side plate is respectively connected with the bottom plate and the top plate, and the second side plate is respectively connected with the bottom plate and the top plate;

a first partition plate disposed between the bottom plate and the top plate to form a first space between the first partition plate and the first side plate, and a second space between the first partition plate and the second side plate;

the second partition plate is positioned in the second space and is arranged between the first partition plate and the second side plate, a third space is formed between the second partition plate and the top plate, and a fourth space is formed between the second partition plate and the bottom plate;

the reaction detection assembly is positioned in the first space and is adjacent to the first partition plate and the fourth space; and

and the optical detection assembly is positioned in the third space and is adjacent to the reaction detection assembly.

2. The sample analyzer of claim 1, further comprising:

The third partition plate is arranged between the bottom plate and the second partition plate, a fifth space is formed between the third partition plate and the first partition plate, and a sixth space is formed between the third partition plate and the second side plate;

the first valve component is arranged on the third partition board and is connected with the reaction detection component in the fifth space; and

and the injector assembly is positioned below the first valve assembly, is arranged on the third partition plate, is connected with the first valve assembly in the sixth space, is used for injecting a reagent into the reaction detection assembly in cooperation with the first valve assembly, is used for extracting a sample which is treated by the reagent in the reaction detection assembly, and is injected into the optical detection assembly.

3. The sample analyzer of claim 2, further comprising:

the second valve assembly is arranged on the third partition plate and positioned in the sixth space and above the injector assembly, the injector assembly is connected with the second valve assembly, and the injector assembly is used for being matched with the second valve assembly to extract reagents which can be injected into the reaction detection assembly.

4. The sample analyzer of claim 3, wherein the housing further comprises:

the third side plate is positioned on the same side of the first side plate and the second side plate, and is respectively connected with the first side plate, the second side plate, the bottom plate and the top plate.

5. The sample analyzer of claim 4, wherein the third side plate is provided with an opening that communicates with the fifth space.

6. The sample analyzer of claim 4, wherein the third side plate is provided with a reagent port extending into the sixth space, the reagent port being connected to the second valve assembly such that the syringe assembly draws reagent through the second valve assembly, the reagent port.

7. The sample analyzer of claim 6, wherein the second valve assembly is closer to the third side plate than the first valve assembly, and the reagent interface is closer to the bottom plate than the second valve assembly.

8. The sample analyzer of claim 6, further comprising:

the air pump assembly is positioned in the fifth space and arranged on the third partition plate, and is adjacent to and connected with the second valve assembly;

The air pump component is positioned in the fifth space and arranged on the third partition board, is positioned below the air pump component and is connected with the second valve component, the air pump component is used for controlling the air pump component to generate negative pressure, and the air pump component is used for extracting waste liquid in the reaction detection component and/or the optical detection component.

9. The sample analyzer of claim 8, further comprising:

and the third valve assembly is arranged on the first partition plate and is adjacent to the air pressure chamber assembly, and is respectively connected with the air pressure chamber assembly, the reaction detection assembly and the optical detection assembly in the fifth space, so that the air pressure chamber assembly can extract the waste liquid in the reaction detection assembly and/or the optical detection assembly through the third valve assembly.

10. The sample analyzer of claim 9, further comprising:

and the liquid pump assembly is arranged in the first space, and the third valve assembly is connected with the liquid pump assembly in the first space, so that the liquid pump assembly can pump the waste liquid in the air pressure chamber assembly through the third valve assembly.

11. The sample analyzer of claim 10, wherein the third side plate is provided with a waste port extending into the first space, the waste port being connected to the liquid pump assembly such that the liquid pump assembly discharges waste from the pneumatic chamber assembly through the waste port.

12. The sample analyzer of claim 9, further comprising:

and the filter assembly is positioned in the fifth space and is installed on the first partition plate, is positioned above the third valve assembly and is arranged adjacent to the air pressure chamber assembly, and is connected with the third valve assembly, the reaction detection assembly and the optical detection assembly so as to filter the waste liquid discharged by the reaction detection assembly and/or the optical detection assembly.

13. The sample analyzer of claim 9, further comprising:

the liquid level and air source detection assembly is located in the sixth space and arranged on the third partition board and is adjacent to the air pressure chamber assembly, the liquid level and air source detection assembly is located below the second valve assembly, the reagent interface is closer to the bottom plate than the liquid level and air source detection assembly, and the liquid level and air source detection assembly is used for detecting negative pressure of the air pressure chamber assembly and detecting reagent liquid level in a liquid path between the reagent interface and the third valve assembly.

14. The sample analyzer of claim 2, further comprising:

and the fourth valve assembly is positioned in the sixth space and is arranged above the injector assembly, is arranged adjacent to the optical detection assembly, and is respectively connected with the optical detection assembly, the reaction detection assembly and the injector assembly, so that the injector assembly can extract the sample which is treated by the reagent in the reaction detection assembly and inject the sample into the optical detection assembly.

15. The sample analyzer of claim 2, wherein the housing further comprises a fourth side plate, the fourth side plate being located on the same side of the first side plate and the second side plate and being connected to the first side plate, the second side plate, the bottom plate and the top plate, respectively, the sample analyzer further comprising:

the cross beam is arranged on the surface of the first partition board in the first space and is positioned above the reaction detection assembly, one end of the cross beam is positioned in the first space, and the other end of the cross beam is positioned outside the shell; and

the sampling assembly comprises a sampling needle which is arranged on the cross beam and can move on the cross beam so as to move from the first space to the outside of the shell or from the outside of the shell to the first space, and the sampling assembly is connected with the injector assembly so as to extract a sample and inject the sample into the reaction detection assembly.

16. The sample analyzer of claim 2, wherein the third partition is provided with a movable portion, and the first valve assembly is provided on the movable portion to completely invert the first valve assembly into the sixth space when the movable portion is inverted.

17. The sample analyzer of claim 1, further comprising:

a fourth partition plate and a fifth partition plate, which are arranged in the first space, are arranged between the first partition plate and the first side plate at intervals, the fourth partition plate is positioned above the reaction detection assembly, the fifth partition plate is arranged between the fourth partition plate and the top plate, and the reaction detection assembly is arranged between the fourth partition plate and the bottom plate; and

and the circuit board assembly is arranged between the fourth partition board and the top board and is used for controlling the sample analyzer.

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