CN116338033A - Liquid phase mass spectrometer with gas cleaning function and use method - Google Patents

Liquid phase mass spectrometer with gas cleaning function and use method Download PDF

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Publication number
CN116338033A
CN116338033A CN202310122837.2A CN202310122837A CN116338033A CN 116338033 A CN116338033 A CN 116338033A CN 202310122837 A CN202310122837 A CN 202310122837A CN 116338033 A CN116338033 A CN 116338033A
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CN
China
Prior art keywords
nozzle
fixedly connected
contact pin
mass spectrometer
liquid phase
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Application number
CN202310122837.2A
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Chinese (zh)
Inventor
杜建兵
刘华芬
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Hangzhou Kailaipu Quality Manufacturing Technology Co ltd
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Hangzhou Kailaipu Quality Manufacturing Technology Co ltd
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Application filed by Hangzhou Kailaipu Quality Manufacturing Technology Co ltd filed Critical Hangzhou Kailaipu Quality Manufacturing Technology Co ltd
Priority to CN202310122837.2A priority Critical patent/CN116338033A/en
Publication of CN116338033A publication Critical patent/CN116338033A/en
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B13/00—Accessories or details of general applicability for machines or apparatus for cleaning
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B5/00—Cleaning by methods involving the use of air flow or gas flow
    • B08B5/02—Cleaning by the force of jets, e.g. blowing-out cavities
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/20—Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

The invention discloses a liquid phase mass spectrometer with a gas cleaning function and a use method thereof, comprising a machine body, a feeding cavity arranged in the machine body, a contact pin arranged in the feeding cavity, a sample rack arranged in the feeding cavity, the contact pin positioned at the top of the sample rack, a compressor fixedly connected with the left side of the machine body, a hose communicated with the output end of the compressor, one end of the hose far away from the compressor penetrating through the interior of the feeding cavity and communicated with a nozzle, a bracket fixedly connected with the left side of the contact pin, one end of the bracket far away from the contact pin extending to the outer side of the nozzle and movably connected with the nozzle through a pin shaft, and a bearing rack fixedly connected with the left side of the contact pin. The invention can improve the functionality of the sampling space structure of the existing liquid phase mass spectrometer, can clean dust in a high-pressure airflow impact mode, reduces the influence of dust attached to the surface of a sealing gum cover at the top of a part of test tube on sampling, and prevents reagent pollution.

Description

Liquid phase mass spectrometer with gas cleaning function and use method
Technical Field
The invention relates to the technical field of liquid phase mass spectrometers, in particular to a liquid phase mass spectrometer with a gas cleaning function and a use method thereof.
Background
The liquid chromatograph-mass spectrometer is an instrument combining liquid chromatograph and mass spectrometer, combines the effective separation heat instability of the liquid chromatograph and the separation capacity of high boiling point compounds with the strong component identification capacity of the mass spectrometer, and is an effective means for separating and analyzing complex organic mixtures.
Liquid phase mass spectrometer needs to run through sample tube with the contact pin and extract liquid in the use, but current liquid phase mass spectrometer sampling space structure is comparatively single, and part test tube top seal gum cover surface can adhere to the dust, and when the contact pin runs through the test tube, part dust can be carried into inside the test tube, causes reagent pollution.
Therefore, design modifications to the liquid phase mass spectrometer are required.
Disclosure of Invention
In order to solve the problems in the prior art, the invention aims to provide a liquid phase mass spectrometer with a gas cleaning function and a use method thereof, which have the advantage of cleaning a test tube by gas flow, and solve the problems that the sampling space structure of the existing liquid phase mass spectrometer is single, dust is attached to the surface of a part of a sealing rubber sleeve at the top of the test tube, and when a contact pin penetrates through the test tube, part of dust is carried into the test tube, so that reagent is polluted.
In order to achieve the above purpose, the present invention provides the following technical solutions: a liquid phase mass spectrometer with air cleaning function and its application method are provided, which comprises a body;
the feeding cavity is arranged in the machine body;
a pin mounted inside the loading chamber;
the inside of material loading cavity is provided with the sample frame, the contact pin is located the top of sample frame, the left side fixedly connected with compressor of organism, the output intercommunication of compressor has the hose, the one end that the compressor was kept away from to the hose runs through to the inside of material loading cavity and communicates there is the nozzle, the left side fixedly connected with support of contact pin, the one end that the contact pin was kept away from to the support extends to the outside of nozzle and through round pin axle and nozzle swing joint.
Preferably, the left side of the contact pin is fixedly connected with a bearing frame, and the bearing frame is hung on the surface of the hose and is in sliding connection with the hose.
As the preferred mode of the invention, the bottom of the contact pin is fixedly connected with a connecting frame, the right side of the connecting frame is provided with a rotating wheel, the left side of the rotating wheel is fixedly connected with a sleeve pipe positioned in the connecting frame, the sleeve pipe is movably connected with the connecting frame, the internal thread of the sleeve pipe is connected with a screw rod, the top of the nozzle is fixedly connected with a transmission plate, and the left end of the screw rod is in contact with the surface of the transmission plate.
As preferable in the invention, the left end of the screw is movably connected with a roller through a pin shaft, and the outer surface of the roller is contacted with the surface of the transmission plate.
As the preferable mode of the invention, the bottom of the plugboard is fixedly connected with the vertical plate, the surface of the screw rod is provided with the limit groove, the front surface of the vertical plate is fixedly connected with the limit rod positioned in the limit groove, and the limit rod is in sliding connection with the limit groove.
Preferably, a spring plate is fixedly connected to the left side of the contact pin, one side of the spring plate, which is far away from the contact pin, extends to the left side of the transmission plate, and the spring plate has elasticity.
As preferable in the invention, the top of the nozzle is fixedly connected with a corner plate, and one side of the corner plate, which is far away from the nozzle, is fixedly connected with the surface of the transmission plate.
A liquid phase mass spectrometer with a gas cleaning function and a use method thereof comprise the following steps:
s1: moving a sample rack storing a sample to the inside of the feeding chamber;
s2: when a sample is extracted and collected, the compressor compresses external air and impacts the sample rack through the hose and the nozzle, so that dust adhered to the surface of the sample rack is separated;
s3: when the impact angle of the nozzle needs to be adjusted, the rotating wheel is rotated, the rotating wheel drives the sleeve to rotate, the sleeve pushes the screw rod to move by utilizing threads, the screw rod can utilize the idler wheel to extrude the transmission plate in the moving process, the nozzle connected with the transmission plate is extruded and swings by taking the pin shaft on the surface of the support as the axis, and therefore the impact angle adjusting effect of the nozzle is achieved.
Compared with the prior art, the invention has the following beneficial effects:
1. the invention can improve the functionality of the sampling space structure of the existing liquid phase mass spectrometer, can clean dust in a high-pressure airflow impact mode, reduces the influence of dust attached to the surface of a sealing gum cover at the top of a part of test tube on sampling, and prevents reagent pollution.
2. According to the invention, the bearing frame is arranged, so that the hose can be supported, and the influence of the hose on the movement of the contact pin is avoided.
Drawings
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is a schematic front view of a partial structure of the present invention;
FIG. 3 is a schematic front view in section of a partial structure of the present invention;
FIG. 4 is a schematic view of a partial structure of the present invention;
FIG. 5 is a schematic perspective view of a partial structure of the present invention;
fig. 6 is an enlarged schematic view of the structure of fig. 2 a according to the present invention.
In the figure: 1. a body; 2. a loading chamber; 3. a contact pin; 4. a sample holder; 5. a compressor; 6. a hose; 7. a nozzle; 8. a bracket; 9. a carrier; 10. a connection frame; 11. a rotating wheel; 12. a sleeve; 13. a screw; 14. a drive plate; 15. a roller; 16. a vertical plate; 17. a limit groove; 18. a limit rod; 19. a spring plate; 20. and (5) a corner plate.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
As shown in fig. 1 to 6, the liquid phase mass spectrometer with the air cleaning function and the use method provided by the invention comprise a machine body 1;
a feeding chamber 2 arranged inside the machine body 1;
a pin 3 mounted inside the feeding chamber 2;
the inside of material loading cavity 2 is provided with sample frame 4, and contact pin 3 is located the top of sample frame 4, and the left side fixedly connected with compressor 5 of organism 1, the output intercommunication of compressor 5 has hose 6, and the one end that compressor 5 was kept away from to hose 6 runs through to the inside of material loading cavity 2 and communicates there is nozzle 7, and the left side fixedly connected with support 8 of contact pin 3, the one end that contact pin 3 was kept away from to support 8 extends to the outside of nozzle 7 and through round pin axle and nozzle 7 swing joint.
Referring to fig. 2, a carrier 9 is fixedly connected to the left side of the pin 3, and the carrier 9 is hung on the surface of the hose 6 and is slidably connected with the hose 6.
As a technical optimization scheme of the invention, the hose 6 can be supported by arranging the bearing frame 9, so that the influence of the hose 6 on the movement of the pin 3 is avoided.
Referring to fig. 4, the bottom of the contact pin 3 is fixedly connected with a connection frame 10, the right side of the connection frame 10 is provided with a rotating wheel 11, the left side of the rotating wheel 11 is fixedly connected with a sleeve 12 positioned in the connection frame 10, the sleeve 12 is movably connected with the connection frame 10, the inside of the sleeve 12 is in threaded connection with a screw 13, the top of the nozzle 7 is fixedly connected with a transmission plate 14, and the left end of the screw 13 is in contact with the surface of the transmission plate 14.
As a technical optimization scheme of the invention, through the arrangement of the connecting frame 10, the sleeve 12 and the screw 13, a user can conveniently adjust the inclination angle of the nozzle 7, and the cleaning requirements of test tubes with different sizes are met.
Referring to fig. 4, a roller 15 is movably connected to the left end of the screw 13 through a pin, and the outer surface of the roller 15 is in contact with the surface of the driving plate 14.
As a technical optimization scheme of the invention, the roller 15 is arranged, so that the driving plate 14 and the screw 13 can be protected, and the screw 13 can release extrusion force conveniently.
Referring to fig. 4, a vertical plate 16 is fixedly connected to the bottom of the plugboard, a limit groove 17 is formed in the surface of the screw 13, a limit rod 18 located inside the limit groove 17 is fixedly connected to the front surface of the vertical plate 16, and the limit rod 18 is slidably connected with the limit groove 17.
As a technical optimization scheme of the invention, the screw 13 can be guided by arranging the vertical plate 16, the limiting groove 17 and the limiting rod 18, so that the screw 13 is prevented from rotating along with the sleeve 12.
Referring to fig. 4, a spring plate 19 is fixedly connected to the left side of the pin 3, one side of the spring plate 19 away from the pin 3 extends to the left side of the driving plate 14, and the spring plate 19 has elasticity.
As a technical optimization scheme of the present invention, the nozzle 7 can be supported by providing the spring plate 19, so that the nozzle 7 is kept in contact with the screw 13.
Referring to fig. 4, the top of the nozzle 7 is fixedly connected with a corner plate 20, and one side of the corner plate 20 away from the nozzle 7 is fixedly connected with the surface of the driving plate 14.
As a technical optimization scheme of the invention, the structure stability of the transmission plate 14 can be improved by arranging the angle plate 20, and the looseness of the joint of the transmission plate 14 and the nozzle 7 can be avoided.
Referring to fig. 1, a liquid phase mass spectrometer with a gas cleaning function and a use method thereof comprise the following steps:
s1: moving the sample holder 4 storing the sample to the inside of the upper chamber 2;
s2: when a sample is extracted and collected, the compressor 5 compresses external air and impacts the sample rack 4 through the hose 6 and the nozzle 7, so that dust adhered on the surface of the sample rack 4 is separated;
s3: when the impact angle of the nozzle 7 needs to be adjusted, the rotating wheel 11 is rotated, the rotating wheel 11 drives the sleeve 12 to rotate, the sleeve 12 pushes the screw 13 to move by using threads, the screw 13 can squeeze the transmission plate 14 by using the roller 15 in the moving process, the nozzle 7 connected with the transmission plate 14 is squeezed and swings by taking a pin shaft on the surface of the bracket 8 as an axis, and therefore the impact angle adjusting effect is achieved.
The working principle and the using flow of the invention are as follows: when the device is used, a user firstly moves the sample rack 4 storing samples into the upper part of the feeding cavity 2, when the pin 3 needs to extract and collect the samples, the compressor 5 compresses external air and impacts the sample rack 4 through the hose 6 and the nozzle 7, dust adhered on the surface of the sample rack 4 is separated, when the impact angle of the nozzle 7 needs to be adjusted, the user rotates the rotating wheel 11, the rotating wheel 11 drives the sleeve 12 to rotate, the sleeve 12 pushes the screw 13 to move by utilizing threads, the screw 13 can push the transmission plate 14 by utilizing the roller 15 in the moving process, and the nozzle 7 connected with the transmission plate 14 is extruded and swings by taking a pin shaft on the surface of the support 8 as an axle center, so that the impact angle of the nozzle is adjusted.
To sum up: according to the liquid phase mass spectrometer with the air cleaning function and the application method, the sampling space structure functionality of the existing liquid phase mass spectrometer can be improved, dust can be cleaned in a high-pressure air flow impact mode, the influence of dust attached to the surface of a sealing rubber sleeve at the top of a part of test tube on sampling is reduced, and reagent pollution is prevented.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (8)

1. A liquid phase mass spectrometer with a gas cleaning function comprises a body (1);
a feeding chamber (2) arranged inside the machine body (1);
a contact pin (3) arranged in the feeding chamber (2);
the method is characterized in that: the inside of material loading cavity (2) is provided with sample frame (4), contact pin (3) are located the top of sample frame (4), the left side fixedly connected with compressor (5) of organism (1), the output intercommunication of compressor (5) has hose (6), the one end that compressor (5) was kept away from to hose (6) is run through to the inside of material loading cavity (2) and is linked together there is nozzle (7), the left side fixedly connected with support (8) of contact pin (3), the one end that contact pin (3) was kept away from to support (8) extends to the outside of nozzle (7) and through round pin axle and nozzle (7) swing joint.
2. The liquid phase mass spectrometer with air cleaning function according to claim 1, wherein: the left side fixedly connected with of contact pin (3) bears frame (9), bear frame (9) hang and establish at the surface of hose (6) and with hose (6) sliding connection.
3. The liquid phase mass spectrometer with air cleaning function according to claim 1, wherein: the bottom fixedly connected with linking bridge (10) of contact pin (3), the right side of linking bridge (10) is provided with runner (11), the left side fixedly connected with of runner (11) is located inside sleeve pipe (12) of linking bridge (10), sleeve pipe (12) and linking bridge (10) swing joint, the inside threaded connection of sleeve pipe (12) has screw rod (13), the top fixedly connected with drive plate (14) of nozzle (7), the left end and the surface contact of drive plate (14) of screw rod (13).
4. A liquid phase mass spectrometer with air cleaning function according to claim 3, wherein: the left end of the screw rod (13) is movably connected with a roller (15) through a pin shaft, and the outer surface of the roller (15) is in contact with the surface of the transmission plate (14).
5. A liquid phase mass spectrometer with air cleaning function according to claim 3, wherein: the bottom fixedly connected with riser (16) of picture peg, spacing groove (17) have been seted up on the surface of screw rod (13), positive fixedly connected with of riser (16) is located spacing inside gag lever post (18) of spacing groove (17), gag lever post (18) and spacing groove (17) sliding connection.
6. A liquid phase mass spectrometer with air cleaning function according to claim 3, wherein: the left side fixedly connected with spring plate (19) of contact pin (3), spring plate (19) keep away from one side of contact pin (3) and extend to the left side of drive plate (14), spring plate (19) have elasticity.
7. A liquid phase mass spectrometer with air cleaning function according to claim 3, wherein: the top of the nozzle (7) is fixedly connected with a corner plate (20), and one side of the corner plate (20) away from the nozzle (7) is fixedly connected with the surface of the transmission plate (14).
8. A method of using a liquid phase mass spectrometer with a gas cleaning function according to any of the preceding claims, characterized in that: the method comprises the following steps:
s1: moving a sample holder (4) storing a sample to the interior of the upper chamber (2);
s2: when a sample is extracted and collected, the compressor (5) compresses external air and impacts the sample rack (4) through the hose (6) and the nozzle (7), so that dust adhered to the surface of the sample rack (4) is separated;
s3: when the impact angle of the nozzle (7) needs to be adjusted, the rotating wheel (11) is rotated, the rotating wheel (11) drives the sleeve (12) to rotate, the sleeve (12) pushes the screw rod (13) to move by using threads, the screw rod (13) can extrude the transmission plate (14) by using the roller (15) in the moving process, the nozzle (7) connected with the transmission plate (14) is extruded and swings by taking the pin shaft on the surface of the bracket (8) as the axis, and therefore the impact angle adjusting effect of the nozzle is achieved.
CN202310122837.2A 2023-02-16 2023-02-16 Liquid phase mass spectrometer with gas cleaning function and use method Pending CN116338033A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310122837.2A CN116338033A (en) 2023-02-16 2023-02-16 Liquid phase mass spectrometer with gas cleaning function and use method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202310122837.2A CN116338033A (en) 2023-02-16 2023-02-16 Liquid phase mass spectrometer with gas cleaning function and use method

Publications (1)

Publication Number Publication Date
CN116338033A true CN116338033A (en) 2023-06-27

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ID=86893791

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202310122837.2A Pending CN116338033A (en) 2023-02-16 2023-02-16 Liquid phase mass spectrometer with gas cleaning function and use method

Country Status (1)

Country Link
CN (1) CN116338033A (en)

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