CN116333873A - Nucleic acid detection device capable of home self-testing, use method and application - Google Patents
Nucleic acid detection device capable of home self-testing, use method and application Download PDFInfo
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- CN116333873A CN116333873A CN202310278069.XA CN202310278069A CN116333873A CN 116333873 A CN116333873 A CN 116333873A CN 202310278069 A CN202310278069 A CN 202310278069A CN 116333873 A CN116333873 A CN 116333873A
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- 238000001514 detection method Methods 0.000 title claims abstract description 76
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 45
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 45
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 45
- 238000012360 testing method Methods 0.000 title claims abstract description 28
- 238000000034 method Methods 0.000 title claims abstract description 16
- 230000003321 amplification Effects 0.000 claims abstract description 28
- 238000003199 nucleic acid amplification method Methods 0.000 claims abstract description 28
- 239000002699 waste material Substances 0.000 claims abstract description 23
- 238000005070 sampling Methods 0.000 claims abstract description 11
- 239000003153 chemical reaction reagent Substances 0.000 claims description 18
- 230000003287 optical effect Effects 0.000 claims description 18
- 238000007789 sealing Methods 0.000 claims description 16
- 238000013016 damping Methods 0.000 claims description 11
- 229920000742 Cotton Polymers 0.000 claims description 10
- 230000000694 effects Effects 0.000 claims description 9
- 241000700605 Viruses Species 0.000 claims description 7
- 239000007795 chemical reaction product Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 208000015181 infectious disease Diseases 0.000 claims description 5
- 230000000903 blocking effect Effects 0.000 claims description 4
- 230000002265 prevention Effects 0.000 claims description 4
- 238000006243 chemical reaction Methods 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 2
- 241000711573 Coronaviridae Species 0.000 description 3
- 238000009434 installation Methods 0.000 description 2
- 239000002906 medical waste Substances 0.000 description 2
- 230000003612 virological effect Effects 0.000 description 2
- 206010036790 Productive cough Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65F—GATHERING OR REMOVAL OF DOMESTIC OR LIKE REFUSE
- B65F1/00—Refuse receptacles; Accessories therefor
- B65F1/14—Other constructional features; Accessories
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65F—GATHERING OR REMOVAL OF DOMESTIC OR LIKE REFUSE
- B65F2240/00—Types of refuse collected
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Engineering & Computer Science (AREA)
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- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Biotechnology (AREA)
- Mechanical Engineering (AREA)
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
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Abstract
The invention discloses a nucleic acid detection device capable of performing home self-test, a using method and application thereof, and belongs to the technical field of nucleic acid detection, the device comprises a mounting plate, wherein a waste collection assembly is arranged at the bottom end of the mounting plate, an upper cover plate is arranged at the upper end of the mounting plate, one end of the upper cover plate is connected with a positioning dismounting assembly, a control plate is arranged between the upper cover plate and the mounting plate, one end of the control plate is provided with a fixing seat, a detection bag is arranged between the positioning dismounting assembly and the mounting plate, one end of the detection bag is connected with an amplification bin corresponding to the fixing seat, and the other end of the detection bag is provided with a plastic nozzle; according to the invention, the waste collection assembly is arranged, so that the mounting plate can be stably mounted and positioned, the stability of the equipment in use is improved, meanwhile, the waste generated by sampling and detection can be uniformly collected, the waste cannot be lost into a household garbage can to cause pollution, the quality of the equipment in use is improved, and the use safety is ensured.
Description
Technical Field
The invention belongs to the technical field of nucleic acid detection, and particularly relates to a nucleic acid detection device capable of performing home self-test, a use method and application.
Background
The substance for nucleic acid detection is a viral nucleic acid. Nucleic acid detection is the finding of whether a human respiratory specimen, blood or stool is infected with a new coronavirus by detecting the presence of foreign invading viral nucleic acid. Thus, once detected as "positive" for nucleic acid, the presence of virus in the patient is demonstrated. After the new coronavirus infects the human body, the new coronavirus is propagated in the respiratory tract system, so that whether the human body infects viruses or not can be judged by detecting virus nucleic acid in sputum and nasopharyngeal swab.
The Chinese patent application No. 202110754803.6 discloses a nucleic acid detection device capable of home self-testing, a use method and application thereof, wherein the nucleic acid detection device comprises a shell and a detection module positioned in the shell; the detection module comprises a detection package and a control element, wherein one end of the detection package is provided with an amplification cabin communicated with the inside of the detection package, the control element comprises a detection light source, an optical sensor, a data processor and an indicator light array, the detection light source is arranged at the amplification cabin, and the optical sensor and the indicator light array are respectively and independently electrically connected with the data processor. The nucleic acid detection device provided by the invention realizes qualitative analysis of the sample to be detected and rapidly and intuitively outputs the detection result, has a simple structure, is easy to operate, has low detection cost, and is suitable for home self-detection.
The above-disclosed patents have the following problems:
1. when the device is used, the reagent in the detection packet is inconvenient to squeeze and convey, the reagent amount in the amplification bin is affected, the detection effect is reduced, meanwhile, the used detection packet is difficult to take out and replace, the device is inconvenient to use, and multiple people cannot be rapidly sampled and detected;
2. medical wastes generated by sampling and used detection bags cannot be collected uniformly in the use process of home self-test, so that infectious sources are scattered and the human health is endangered easily due to random throwing.
Disclosure of Invention
To solve the problems set forth in the background art. The invention provides a nucleic acid detection device capable of performing home self-test, a use method and application thereof, and has the characteristics of unified collection of medical wastes and convenience in disassembly and assembly of a detection package.
In order to achieve the above purpose, the present invention provides the following technical solutions: the utility model provides a nucleic acid detection device that can family's self-test, includes the mounting panel, the bottom of mounting panel is provided with the waste collection subassembly, and the upper end of mounting panel is provided with the upper cover plate, and the one end of upper cover plate is connected with location dismouting subassembly, is provided with the control panel between upper cover plate and the mounting panel, and the one end of control panel is provided with the fixing base, is provided with the detection package between location dismouting subassembly and the mounting panel, and the one end that detects the package corresponds the fixing base and is connected with the amplification storehouse, and the other end that detects the package is provided with the plastic nozzle.
Further in the present invention; the waste collection assembly comprises a T-shaped sliding rail, a collection box, a sealing plate and a fixed torsion spring, wherein the bottom end of the mounting plate is provided with the collection box, the upper end of the collection box is symmetrically provided with the T-shaped sliding rail, the fixed torsion spring is arranged in the collection box, and one side of the fixed torsion spring is connected with the sealing plate.
Further in the present invention; suction cups are arranged at four corners of the bottom end of the collecting box.
Further in the present invention; the inside bottom of collecting box is provided with the manger plate piece.
Further in the present invention; the positioning disassembly and assembly comprises a positioning plug, a sliding groove, a sliding rod, a connecting torsion spring and a movable cover plate, wherein the connecting torsion spring is symmetrically arranged at one end of the upper cover plate, the movable cover plate is connected with one end of the connecting torsion spring, the sliding groove is formed in the movable cover plate, the sliding rod penetrates through the sliding groove, and the positioning plug is arranged at the bottom end of the movable cover plate.
Further in the present invention; the inside of movable cover plate is provided with the damping pivot, and the bottom of damping pivot is connected with L type support.
Further in the present invention; one end of the movable cover plate is provided with a finger groove, and the edge of the finger groove is passivated.
The invention also provides a method for using the nucleic acid detection device capable of home self-testing, which comprises the following steps:
(1) the collecting box is sucked on the tabletop through the sucker to be fixed, then the bottom end of the mounting plate is installed corresponding to the T-shaped sliding rail in a sliding way, after the equipment is stably installed on the tabletop, the nose swab is collected through the cotton swab, then the plastic nozzle is opened to insert the cotton swab into the detection bag and stir, and the nose swab is fully mixed with the nucleic acid extraction reagent in the detection bag;
(2) the finger is inserted into a finger groove in the movable cover plate, the movable cover plate is rotated along a connecting torsion spring to open the movable cover plate, then the damping rotating shaft is rotated to take out the L-shaped bracket from the movable cover plate, the L-shaped bracket is abutted to the upper end of the mounting plate to support the movable cover plate, then one end of the amplification bin is inserted into the fixing seat to be fixed, the L-shaped bracket is rotated after the mounting is completed to reset the connecting torsion spring, the movable cover plate is reset to enable the positioning plug to be inserted into the mounting plate, at the moment, the slide bar compresses the detection bag, then the slide bar is pushed downwards along the slide groove to move, and meanwhile the slide bar extrudes reagents in the detection bag into the amplification bin;
(3) the control board controls the fixing seat to heat the reagent mixture in the internal amplification bin to finish the nucleic acid amplification reaction to obtain a reaction product, the reaction product is irradiated by the detection light source to generate an optical signal, the optical sensor receives the optical signal and transmits the optical signal to the control board, and the control board instructs the indicator lamp array to display a positive or negative detection result according to the optical signal;
(4) the movable cover plate is opened again to pull out the amplification bin from the inside of the fixed seat, then the sealing plate is pressed to enable the amplification bin to rotate along the fixed torsion spring, then the used sampling cotton swabs and detection bags are fed into the inside of the collection box to be collected, the sealing plate is loosened to enable the fixed torsion spring to reset, the collection box can be closed, the infection source activity caused by the messy throwing of sampling waste generated in the household self-testing process is prevented, the virus prevention and control effect is improved, meanwhile, the reagent leakage can be effectively prevented by the set water blocking block, and the safety of waste collection is improved.
The invention also provides the application of the nucleic acid detection device capable of home self-testing: the nucleic acid detection device is used for detecting nucleic acid samples of various types and scenes in real time.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the invention, the waste collection assembly is arranged, so that the mounting plate can be stably mounted and positioned, the stability of the equipment in use is improved, meanwhile, the waste generated by sampling and detection can be uniformly collected, the waste cannot be lost into a household garbage can to cause pollution, the quality of the equipment in use is improved, and the use safety is ensured.
2. According to the invention, the positioning dismounting assembly is arranged, so that the movable cover plate can be conveniently opened and closed, the convenience of dismounting the detection bag is improved, the manpower resources are saved, the using effect of equipment is ensured, meanwhile, the sliding rod can be moved along the sliding groove to enable the reagent in the detection bag to flow into the amplification bin, the quality of reagent detection is ensured, and the illumination detection effect is improved.
Drawings
FIG. 1 is a perspective view of the structure of the present invention;
FIG. 2 is a structural exploded view of the present invention;
FIG. 3 is a schematic view of a waste collection assembly according to the present invention;
fig. 4 is a schematic structural diagram of a positioning assembly and disassembly assembly according to the present invention.
In the figure: 1. a plastic mouth; 2. positioning the dismounting component; 21. positioning a plug; 22. a chute; 23. a slide bar; 24. damping the rotating shaft; 25. connecting a torsion spring; 26. an L-shaped bracket; 27. a removable cover; 3. an upper cover plate; 4. a mounting plate; 5. a waste collection assembly; 51. a T-shaped slide rail; 52. a collection box; 53. a sealing plate; 54. fixing the torsion spring; 55. a suction cup; 56. a water blocking block; 6. detecting a packet; 7. an amplification bin; 8. a fixing seat; 9. and (5) a control panel.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In a specific embodiment, the invention provides a nucleic acid detection device capable of performing home self-test, which is shown in fig. 1-4, and comprises a mounting plate 4, wherein a waste collection assembly 5 is arranged at the bottom end of the mounting plate 4, an upper cover plate 3 is arranged at the upper end of the mounting plate 4, one end of the upper cover plate 3 is connected with a positioning dismounting assembly 2, a control plate 9 is arranged between the upper cover plate 3 and the mounting plate 4, a fixed seat 8 is arranged at one end of the control plate 9, a detection package 6 is arranged between the positioning dismounting assembly 2 and the mounting plate 4, an amplification bin 7 is connected at one end of the detection package 6 corresponding to the fixed seat 8, and a plastic nozzle 1 is arranged at the other end of the detection package 6.
Specifically, the waste collection assembly 5 includes a T-shaped slide rail 51, a collection box 52, a sealing plate 53 and a fixed torsion spring 54, wherein the bottom end of the mounting plate 4 is provided with the collection box 52, the upper end of the collection box 52 is symmetrically provided with the T-shaped slide rail 51, the inside of the collection box 52 is provided with the fixed torsion spring 54, and one side of the fixed torsion spring 54 is connected with the sealing plate 53.
By adopting the technical scheme, the collecting box 52 is sucked on the desktop through the sucking disc 55 to be fixed, and then the bottom end of the mounting plate 4 is mounted by sliding corresponding to the T-shaped sliding rail 51, so that the equipment is ensured to be stably mounted on the desktop; after the nucleic acid detection is completed, the sealing plate 53 is pressed to enable the sealing plate 53 to rotate along the fixed torsion spring 54, then the used sampling cotton swabs and the detection bag 6 are sent into the collecting box 52 for collection, the sealing plate 53 is loosened to enable the fixed torsion spring 54 to reset, the collecting box 52 can be sealed, the phenomenon that infection sources are scattered due to scattered sampling waste generated in the household self-testing process is prevented, and the virus prevention and control effect is improved.
Specifically, suction cups 55 are provided at four corners of the bottom end of the collection box 52.
By adopting the above technical scheme, the stability of the collecting box 52 mounted on the desktop is improved, and the use quality of the device is ensured.
Specifically, the inner bottom end of the collection box 52 is provided with a water stop 56.
By adopting the above technical scheme, the water stop 56 can effectively prevent reagent leakage and improve the safety of waste collection.
Specifically, the positioning dismounting assembly 2 comprises a positioning plug 21, a sliding groove 22, a sliding rod 23, a connecting torsion spring 25 and a movable cover plate 27, wherein the connecting torsion spring 25 is symmetrically arranged at one end of the upper cover plate 3, the movable cover plate 27 is connected with one end of the connecting torsion spring 25, the sliding groove 22 is arranged in the movable cover plate 27, the sliding rod 23 penetrates through the sliding groove 22, and the positioning plug 21 is arranged at the bottom end of the movable cover plate 27.
Through adopting above-mentioned technical scheme, the finger inserts in the inside finger groove of removable cover 27, rotate removable cover 27 again along connecting torsional spring 25 and open it, then rotate damping pivot 24 and take out L type support 26 from the inside of removable cover 27, and make L type support 26 butt support removable cover 27 at the upper end of mounting panel 4, then insert the inside of fixing base 8 with the one end of expansion storehouse 7 and fix, ensure that the installation is accomplished the back and rotate L type support 26 and make connecting torsional spring 25 reset, removable cover 27 resets and makes positioning plug 21 insert the inside of mounting panel 4, slide bar 23 compresses tightly detection package 6 this moment, then promote slide bar 23 down along spout 22 and remove, slide bar 23 squeezes the inside of expansion storehouse 7 with the reagent in the detection package 6 simultaneously.
Specifically, a damping rotating shaft 24 is arranged in the movable cover plate 27, and an L-shaped bracket 26 is connected to the bottom end of the damping rotating shaft 24.
Through adopting above-mentioned technical scheme, support the removable cover 27 through L type support 26, guarantee to detect the convenience of package 6 installation, need not long-time manual support removable cover 27.
Specifically, one end of the movable cover plate 27 is provided with a finger groove, and the edge of the finger groove is passivated.
By adopting the technical scheme, the comfort level of opening and closing the movable cover plate 27 is improved, and hand scratches are prevented.
In another embodiment, the invention provides a method for using a home-self-testing nucleic acid detection device, comprising:
(1) the collecting box 52 is sucked on a table top through the sucking disc 55 to be fixed, then the bottom end of the mounting plate 4 is installed by sliding corresponding to the T-shaped sliding rail 51, after the equipment is stably installed on the table top, a nose swab is collected through a cotton swab, then the cotton swab is inserted into the detection bag 6 through the plastic nozzle 1 and stirred, and the nose swab is fully mixed with a nucleic acid extraction reagent in the detection bag 6;
(2) the finger is inserted into a finger groove in the movable cover plate 27, the movable cover plate 27 is rotated along the connecting torsion spring 25 to open the movable cover plate 27, then the damping rotating shaft 24 is rotated to take the L-shaped bracket 26 out of the movable cover plate 27, the L-shaped bracket 26 is abutted against the upper end of the mounting plate 4 to support the movable cover plate 27, then one end of the amplification bin 7 is inserted into the fixed seat 8 to be fixed, the L-shaped bracket 26 is rotated after the completion of the mounting to ensure that the connecting torsion spring 25 is reset, the movable cover plate 27 is reset to enable the positioning plug 21 to be inserted into the mounting plate 4, the slide bar 23 compresses the detection bag 6 at the moment, then the slide bar 23 is pushed downwards along the slide groove 22 to move, and meanwhile, the slide bar 23 extrudes a reagent in the detection bag 6 into the amplification bin 7;
(3) the control board 9 controls the fixing seat 8 to heat the reagent mixture in the internal amplification bin 7, the nucleic acid amplification reaction is completed to obtain a reaction product, the reaction product is irradiated by the detection light source to generate an optical signal, the optical sensor receives the optical signal and transmits the optical signal to the control board 9, and the control board 9 instructs the lamp array to display a positive or negative detection result according to the optical signal;
(4) the movable cover plate 27 is opened again to pull out the amplification bin 7 from the inside of the fixed seat 8, then the sealing plate 53 is pressed to enable the amplification bin to rotate along the fixed torsion spring 54, the used sampling cotton swabs and the detection bag 6 are sent into the collecting box 52 to be collected, the sealing plate 53 is loosened to enable the fixed torsion spring 54 to reset, the collecting box 52 can be closed, the infection source is prevented from being dispersed due to the fact that sampling waste generated in the household self-testing process is thrown randomly, the virus prevention and control effect is improved, meanwhile, the water blocking block 56 can effectively prevent reagent leakage, and the waste collection safety is improved.
In another embodiment, the invention provides an application of the home-self-testing nucleic acid detecting apparatus according to the above embodiment, wherein the home-self-testing nucleic acid detecting apparatus is used for detecting nucleic acid samples of various types and scenes in real time, including but not limited to customs, families, schools and other public places.
The structure and the use principle of the amplification bin 7, the fixing seat 8 and the control panel 9 in the invention are disclosed in a nucleic acid detection device capable of home self-testing, a use method and application thereof disclosed in China patent application No. 202110754803.6, wherein the amplification bin 7 is made of a light-transmitting material, a detection light source is arranged in the fixing seat 8, and the control panel 9 comprises an optical sensor, a temperature sensor, an indicator light array and a data processor.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (9)
1. The utility model provides a nucleic acid detection device that can family's self-test, includes mounting panel, its characterized in that: the bottom of mounting panel is provided with the waste collection subassembly, and the upper end of mounting panel is provided with the upper cover plate, and the one end of upper cover plate is connected with location dismouting subassembly, is provided with the control panel between upper cover plate and the mounting panel, and the one end of control panel is provided with the fixing base, is provided with between location dismouting subassembly and the mounting panel and detects the package, and the one end that detects the package corresponds the fixing base and is connected with the expansion storehouse, and the other end that detects the package is provided with the plastic nozzle.
2. The home-self-test nucleic acid detecting apparatus according to claim 1, wherein: the waste collection assembly comprises a T-shaped sliding rail, a collection box, a sealing plate and a fixed torsion spring, wherein the bottom end of the mounting plate is provided with the collection box, the upper end of the collection box is symmetrically provided with the T-shaped sliding rail, the fixed torsion spring is arranged in the collection box, and one side of the fixed torsion spring is connected with the sealing plate.
3. The home-self-test nucleic acid detecting apparatus according to claim 2, wherein: suction cups are arranged at four corners of the bottom end of the collecting box.
4. The home-self-test nucleic acid detecting apparatus according to claim 2, wherein: the inside bottom of collecting box is provided with the manger plate piece.
5. The home-self-test nucleic acid detecting apparatus according to claim 1, wherein: the positioning disassembly and assembly comprises a positioning plug, a sliding groove, a sliding rod, a connecting torsion spring and a movable cover plate, wherein the connecting torsion spring is symmetrically arranged at one end of the upper cover plate, the movable cover plate is connected with one end of the connecting torsion spring, the sliding groove is formed in the movable cover plate, the sliding rod penetrates through the sliding groove, and the positioning plug is arranged at the bottom end of the movable cover plate.
6. The home-self-test nucleic acid detecting apparatus according to claim 5, wherein: the inside of movable cover plate is provided with the damping pivot, and the bottom of damping pivot is connected with L type support.
7. The home-self-test nucleic acid detecting apparatus according to claim 5, wherein: one end of the movable cover plate is provided with a finger groove, and the edge of the finger groove is passivated.
8. A method of using a home-self-testing nucleic acid testing device according to any one of claims 1-7, comprising: the using method comprises the following steps:
(1) the collecting box is sucked on the tabletop through the sucker to be fixed, then the bottom end of the mounting plate is installed corresponding to the T-shaped sliding rail in a sliding way, after the equipment is stably installed on the tabletop, the nose swab is collected through the cotton swab, then the plastic nozzle is opened to insert the cotton swab into the detection bag and stir, and the nose swab is fully mixed with the nucleic acid extraction reagent in the detection bag;
(2) the finger is inserted into a finger groove in the movable cover plate, the movable cover plate is rotated along a connecting torsion spring to open the movable cover plate, then the damping rotating shaft is rotated to take out the L-shaped bracket from the movable cover plate, the L-shaped bracket is abutted to the upper end of the mounting plate to support the movable cover plate, then one end of the amplification bin is inserted into the fixing seat to be fixed, the L-shaped bracket is rotated after the mounting is completed to reset the connecting torsion spring, the movable cover plate is reset to enable the positioning plug to be inserted into the mounting plate, at the moment, the slide bar compresses the detection bag, then the slide bar is pushed downwards along the slide groove to move, and meanwhile the slide bar extrudes reagents in the detection bag into the amplification bin;
(3) the control board controls the fixing seat to heat the reagent mixture in the internal amplification bin to finish the nucleic acid amplification reaction to obtain a reaction product, the reaction product is irradiated by the detection light source to generate an optical signal, the optical sensor receives the optical signal and transmits the optical signal to the control board, and the control board instructs the indicator lamp array to display a positive or negative detection result according to the optical signal;
(4) the movable cover plate is opened again to pull out the amplification bin from the inside of the fixed seat, then the sealing plate is pressed to enable the amplification bin to rotate along the fixed torsion spring, then the used sampling cotton swabs and detection bags are fed into the inside of the collection box to be collected, the sealing plate is loosened to enable the fixed torsion spring to reset, the collection box can be closed, the infection source activity caused by the messy throwing of sampling waste generated in the household self-testing process is prevented, the virus prevention and control effect is improved, meanwhile, the reagent leakage can be effectively prevented by the set water blocking block, and the safety of waste collection is improved.
9. Use of a home-self-testable nucleic acid detection device according to any one of claims 1-7, characterized in that: the nucleic acid detection device is used for detecting nucleic acid samples of various types and scenes in real time.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310278069.XA CN116333873A (en) | 2023-03-20 | 2023-03-20 | Nucleic acid detection device capable of home self-testing, use method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310278069.XA CN116333873A (en) | 2023-03-20 | 2023-03-20 | Nucleic acid detection device capable of home self-testing, use method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116333873A true CN116333873A (en) | 2023-06-27 |
Family
ID=86892496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310278069.XA Pending CN116333873A (en) | 2023-03-20 | 2023-03-20 | Nucleic acid detection device capable of home self-testing, use method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116333873A (en) |
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2023
- 2023-03-20 CN CN202310278069.XA patent/CN116333873A/en active Pending
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