CN116323926A - 麝香香料成分的生产方法 - Google Patents

麝香香料成分的生产方法 Download PDF

Info

Publication number
CN116323926A
CN116323926A CN202180060219.9A CN202180060219A CN116323926A CN 116323926 A CN116323926 A CN 116323926A CN 202180060219 A CN202180060219 A CN 202180060219A CN 116323926 A CN116323926 A CN 116323926A
Authority
CN
China
Prior art keywords
formula
compound
ala
gly
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180060219.9A
Other languages
English (en)
Chinese (zh)
Inventor
M·比尔曼
F·茹赛
M·波克拉
陈海滨
何魁芳
石淑敏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Givaudan SA
Original Assignee
Givaudan SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan SA filed Critical Givaudan SA
Publication of CN116323926A publication Critical patent/CN116323926A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/0026—Essential oils; Perfumes compounds containing an alicyclic ring not condensed with another ring
    • C11B9/0038—Essential oils; Perfumes compounds containing an alicyclic ring not condensed with another ring the ring containing more than six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/0069—Heterocyclic compounds
    • C11B9/0073—Heterocyclic compounds containing only O or S as heteroatoms
    • C11B9/0084—Heterocyclic compounds containing only O or S as heteroatoms the hetero rings containing more than six atoms
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/02—Recovery or refining of essential oils from raw materials
    • C11B9/027—Recovery of volatiles by distillation or stripping
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202180060219.9A 2020-07-21 2021-07-20 麝香香料成分的生产方法 Pending CN116323926A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2011259.5 2020-07-21
GBGB2011259.5A GB202011259D0 (en) 2020-07-21 2020-07-21 Method for the production of musk fragrance ingredient
PCT/CN2021/107393 WO2022017389A1 (en) 2020-07-21 2021-07-20 Method for the production of musk fragrance ingredient

Publications (1)

Publication Number Publication Date
CN116323926A true CN116323926A (zh) 2023-06-23

Family

ID=72338876

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180060219.9A Pending CN116323926A (zh) 2020-07-21 2021-07-20 麝香香料成分的生产方法

Country Status (9)

Country Link
US (1) US12612353B2 (https=)
EP (1) EP4185562A4 (https=)
JP (1) JP2023534711A (https=)
CN (1) CN116323926A (https=)
BR (1) BR112023001015A2 (https=)
GB (1) GB202011259D0 (https=)
IL (1) IL299969A (https=)
MX (1) MX2022015219A (https=)
WO (1) WO2022017389A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025168763A1 (en) 2024-02-09 2025-08-14 International Flavors & Fragrances Inc. Enzymatic method for the production of enriched musk fragrance

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101970665A (zh) * 2008-01-28 2011-02-09 生物结构实验室公司 分离的醇脱氢酶酶类及其用途
WO2015066722A1 (en) * 2013-11-04 2015-05-07 Bgn Tech Llc Methods of making vanillin via the microbial fermentation of ferulic acid from eugenol using a plant dehydrogenase.
US20160340606A1 (en) * 2014-01-14 2016-11-24 Firmenich Sa Powdery, musky odorant macrocycles
CN109890972A (zh) * 2016-10-26 2019-06-14 味之素株式会社 生产目标物质的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007076109A2 (en) 2005-12-23 2007-07-05 Biocatalytics, Inc. Method of making(+)-sitophilure
JP2014506115A (ja) * 2010-09-15 2014-03-13 アリグナ テクノロジーズ，インク． リグニン由来の化合物からの芳香族化学物質のバイオプロダクション
US20120202257A1 (en) * 2010-09-16 2012-08-09 Ranjini Chatterjee Lige-type enzymes for bioconversion of lignin-derived compounds
CN107001214B (zh) * 2014-12-26 2021-03-23 花王株式会社 环状二酮化合物的制造方法
CN119059879A (zh) 2015-08-06 2024-12-03 国际香料和香精公司 取代烯烃的环丙烷化
EP3170828A1 (de) * 2015-11-23 2017-05-24 Basf Se Verfahren zur herstellung von verbindungen mit 16-oxabicyclo[10.3.1]pentadecengerüst und deren folgeprodukten
JP7039551B2 (ja) * 2016-07-15 2022-03-22 ビーエーエスエフ ソシエタス・ヨーロピア ３－メチル－１，５－シクロペンタデカンジオンからの１４－メチル－１６－オキサビシクロ［１０．３．１］ペンタデセンの調製
CN112771051B (zh) * 2018-09-28 2022-04-05 花王株式会社 环状烯醇醚化合物的制造方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101970665A (zh) * 2008-01-28 2011-02-09 生物结构实验室公司 分离的醇脱氢酶酶类及其用途
WO2015066722A1 (en) * 2013-11-04 2015-05-07 Bgn Tech Llc Methods of making vanillin via the microbial fermentation of ferulic acid from eugenol using a plant dehydrogenase.
US20160340606A1 (en) * 2014-01-14 2016-11-24 Firmenich Sa Powdery, musky odorant macrocycles
CN109890972A (zh) * 2016-10-26 2019-06-14 味之素株式会社 生产目标物质的方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BAUGH, L.等: "Chain A ，short chain dehydrogenase, PDB:3TJR_A", 《ORIGIN》, 27 January 2018 (2018-01-27), pages 1 *
朱诚等: "醇脱氢酶KpADH的127位点对催化活性和对映选择性的影响", 《化工进展》, vol. 38, no. 12, 8 August 2019 (2019-08-08), pages 5504 - 5511 *

Also Published As

Publication number Publication date
WO2022017389A1 (en) 2022-01-27
EP4185562A4 (en) 2025-08-06
EP4185562A1 (en) 2023-05-31
IL299969A (en) 2023-03-01
GB202011259D0 (en) 2020-09-02
JP2023534711A (ja) 2023-08-10
US20240182395A1 (en) 2024-06-06
MX2022015219A (es) 2023-01-05
US12612353B2 (en) 2026-04-28
BR112023001015A2 (pt) 2023-02-14

Similar Documents

Publication Publication Date Title
JP7603041B2 (ja) 酵素およびその適用
US11091752B2 (en) Squalene hopene cyclase and use thereof for producing ambroxan
US12584153B2 (en) Enzyme-mediated process for making Amberketal and Amberketal homologues
US20250361536A1 (en) Squalene hopene cyclase (shc) variants
US11965195B2 (en) Enzyme mediated process
JP2025509737A (ja) Ｓｈｃ酵素および酵素バリアント
EP4208546B1 (en) Squalene hopene cyclase derivatives and use thereof for producing ambrox
CN116323926A (zh) 麝香香料成分的生产方法
RU2829857C9 (ru) Варианты скваленгопенциклазы (shc)
RU2829857C1 (ru) Варианты скваленгопенциклазы (shc)
BR122023025399A2 (pt) Enzimas de esqualeno hopeno ciclase (sch) e suas variantes, produtos de conversão enzimática, seus processos de preparação e produtos derivados

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination