CN116296682A - Totally-enclosed pathological biological tissue dehydrator and application method thereof - Google Patents
Totally-enclosed pathological biological tissue dehydrator and application method thereof Download PDFInfo
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- CN116296682A CN116296682A CN202310293610.4A CN202310293610A CN116296682A CN 116296682 A CN116296682 A CN 116296682A CN 202310293610 A CN202310293610 A CN 202310293610A CN 116296682 A CN116296682 A CN 116296682A
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- 230000001575 pathological effect Effects 0.000 title claims abstract description 73
- 238000000034 method Methods 0.000 title claims abstract description 23
- 239000012024 dehydrating agents Substances 0.000 claims abstract description 71
- 230000007246 mechanism Effects 0.000 claims abstract description 65
- 238000005086 pumping Methods 0.000 claims abstract description 52
- 239000007921 spray Substances 0.000 claims abstract description 42
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 31
- 239000007788 liquid Substances 0.000 claims abstract description 15
- 230000009471 action Effects 0.000 claims abstract description 5
- 208000005156 Dehydration Diseases 0.000 claims description 26
- 230000018044 dehydration Effects 0.000 claims description 26
- 238000006297 dehydration reaction Methods 0.000 claims description 26
- 230000001502 supplementing effect Effects 0.000 claims description 23
- 238000011282 treatment Methods 0.000 claims description 18
- 230000005540 biological transmission Effects 0.000 claims description 17
- 238000002791 soaking Methods 0.000 claims description 10
- 238000000605 extraction Methods 0.000 claims description 7
- 238000005096 rolling process Methods 0.000 claims description 3
- 230000007170 pathology Effects 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 230000009469 supplementation Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 abstract description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 23
- 230000008569 process Effects 0.000 description 15
- 230000033001 locomotion Effects 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000007598 dipping method Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 239000012188 paraffin wax Substances 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- -1 70% ethanol Chemical compound 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 125000004430 oxygen atom Chemical group O* 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P70/00—Climate change mitigation technologies in the production process for final industrial or consumer products
- Y02P70/10—Greenhouse gas [GHG] capture, material saving, heat recovery or other energy efficient measures, e.g. motor control, characterised by manufacturing processes, e.g. for rolling metal or metal working
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- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
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Abstract
The invention relates to the field of pathological biological tissue detection, in particular to a totally-enclosed pathological biological tissue dehydrator and a use method thereof, wherein the totally-enclosed pathological biological tissue dehydrator comprises a cabinet body and a cylinder arranged in the cabinet body, and further comprises: the two spray heads are movably arranged in the cylinder, the two spray heads are respectively connected with a group of height adjusting mechanisms arranged in the cylinder, the two spray heads are connected with a circulating pumping mechanism arranged in the cabinet body, the circulating pumping mechanism is used for pumping the dehydrating agent and pumping the dehydrating agent into the cylinder along the tangential direction of the inner wall of the cylinder, the two spray heads alternately execute the dehydrating agent pumping action so as to enable two vortex flows with opposite rotation directions to be alternately formed in the cylinder, simultaneously, the dehydrating agent pumped by the circulating pumping mechanism can be pumped upwards from the bottom of the cylinder to form a plurality of liquid columns, finally, the flow of the dehydrating agent in the cylinder can be accelerated, and the replacement rate of the dehydrating agent to the water in the pathological biological tissue can be improved, so that the dehydrating efficiency can be greatly improved.
Description
Technical Field
The invention relates to the field of pathological biological tissue detection, in particular to a totally-enclosed pathological biological tissue dehydrator and a use method thereof.
Background
The narrow concept of tissue dehydration is a process in which water in tissue is gradually replaced by using some chemical solvents that are compatible with water as a medium to replace water in tissue. In pathological technology, a generalized dehydration concept is often used, namely, tissue dehydration is a process of tissue pretreatment, namely, the obtained tissue is subjected to the processes of supplementary fixation, dehydration, transparency and wax dipping, and the purpose of the tissue dehydration treatment is to facilitate the wax dipping of the next tissue. Water is not miscible with paraffin, and if only a small amount of water remains in the tissue, it will prevent paraffin penetration.
At present, when the existing pathological biological tissue dehydrator is actually used, the pathological biological tissue is usually soaked in a dehydrating agent, the whole soaking process is in a static state, the pathological biological tissue possibly generates a sinking phenomenon due to high density, and the dehydrating treatment mode has low substitution rate of the dehydrating agent on the moisture in the pathological biological tissue, so that the treatment time is long, and the ideal dehydrating efficiency is difficult to achieve.
Disclosure of Invention
The invention aims to provide a totally-enclosed pathological biological tissue dehydrator and a use method thereof, so as to solve the problems in the background technology.
In order to achieve the above purpose, the present invention provides the following technical solutions:
the utility model provides a totally closed pathology biological tissue hydroextractor, includes the cabinet body and locates the inside of cabinet body is used for splendid attire dehydrating agent's drum, still includes:
the two spray heads are movably arranged in the cylinder, a group of height adjusting mechanisms installed in the cylinder are respectively connected with the two spray heads, the two spray heads are connected with a circulating pumping mechanism installed in the cabinet body, the circulating pumping mechanism is used for pumping a dehydrating agent in the cylinder and pumping the dehydrating agent into the cylinder along the tangential direction of the inner wall of the cylinder through the spray heads, the two spray heads alternately execute the dehydrating agent pumping action so as to alternately form two vortex flows with opposite rotation directions in the cylinder, and meanwhile, the dehydrating agent pumped by the circulating pumping mechanism is pumped upwards from the bottom of the cylinder and forms a plurality of liquid columns in the cylinder so as to promote pathological biological tissues in the cylinder to maintain a suspension state;
the solute supplementing mechanism is arranged in the cabinet body and used for pumping solute into the cylinder, the solute supplementing mechanism gradually increases the amount of the solute pumped into the cabinet body so as to enable the concentration of the dehydrating agent in the cylinder to be changed in an increasing trend, and the solute supplementing mechanism is also connected with the height adjusting mechanism, when the solute supplementing mechanism pumps the solute into the cylinder, the height adjusting mechanism is driven to drive the spray head to rise, so that vortex can be formed when the spray head executes the dehydrating agent pumping action.
As a further scheme of the invention: the circulating pumping mechanism comprises a water pump arranged in the cabinet body, a water inlet of the water pump is connected with a guide pipe, the guide pipe stretches into the cylinder, a water outlet of the water pump is connected with a three-way pipe, and two interfaces on the three-way pipe are respectively connected with a disc and an electronic ball valve;
the electronic ball valve is characterized in that the disc is hollow, a plurality of small holes are formed in the upper portion of the disc, and two interfaces on the electronic ball valve are connected with two spray heads through hoses respectively.
As still further aspects of the invention: the height adjusting mechanism comprises two rotating wheels rotatably mounted on the inner wall of the cylinder, a connecting piece for connecting the two rotating wheels and an assembling block arranged on one side of the connecting piece, the connecting piece is in rolling fit with the two rotating wheels, and the spray head is mounted on the assembling block;
the rotating shaft of one rotating wheel is connected with a transmission shaft rotatably arranged on the outer wall of the cylinder through a bevel gear set, the transmission shaft is connected with a connecting shaft rotatably arranged on the outer wall of the cylinder through a first transmission belt, and the connecting shaft is connected with the solute supplementing mechanism.
As still further aspects of the invention: the solute supplementing mechanism comprises an extraction pumping assembly arranged on the outer wall of the cylinder and a circumferential rotating assembly arranged on the inner wall of the cabinet body and matched with the extraction pumping structure, and the circumferential rotating assembly is connected with the connecting shaft.
As still further aspects of the invention: the pumping assembly comprises a box body arranged on the outer wall of the cylinder, a piston plate arranged in the box body in a sealing sliding manner, and a first one-way valve and a second one-way valve which are arranged on the box body;
the piston plate is connected with a connecting plate, one end, far away from the piston plate, of the connecting plate is connected with an elastic structure arranged on the outer wall of the cylinder, the first one-way valve is connected with a solute storage tank arranged outside, and the second one-way valve is connected with the cylinder through a connecting pipe.
As still further aspects of the invention: the elastic structure comprises two upright posts arranged on the outer wall of the cylinder through protruding blocks and a sliding plate which is arranged on the two upright posts in a sliding manner and is connected with one end, far away from the piston plate, of the connecting plate, and a driven plate matched with the circumferential rotating assembly is arranged on one side, far away from the cylinder, of the sliding plate;
wherein, two the periphery of stand respectively overlaps and is equipped with a cylindricality spring, the one end of cylindricality spring is connected the protruding piece, the other end with the sliding plate is connected.
As still further aspects of the invention: the circumferential rotation assembly comprises a driving motor, a rotation plate and a sliding block, wherein the driving motor is installed on the inner wall of the cabinet body, the rotation plate is arranged at the tail end of an output shaft of the driving motor, the sliding block is arranged on the rotation plate in a sliding mode, and the output shaft of the driving motor is connected with the connecting shaft through a second transmission belt;
the sliding block is connected with a radial length adjusting structure arranged on the rotating plate, and a pulley abutted with the driven plate is rotatably arranged on one side of the sliding block, which faces the driven plate.
As still further aspects of the invention: the diameter length adjusting structure comprises a screw rod rotatably mounted on the rotating plate and a threaded sleeve sleeved on the screw rod and in threaded connection with the screw rod, and the threaded sleeve is fixed with the sliding block;
the gear is installed to one end of lead screw, be provided with the arc spare on the box, the arc spare with the coincidence of the central axis of driving motor output shaft two, just be equipped with on the arc spare with gear complex tooth.
The application method of the totally-enclosed pathological biological tissue dehydrator comprises the following steps:
opening a through hole at the top of the cylinder, introducing a dehydrating agent with a first gradient into the cylinder, putting pathological biological tissues to be dehydrated into the cylinder, and closing the through hole;
step two, the circulating pumping mechanism works, vortex and liquid column are generated in the cylinder, the flow rate of a dehydrating agent is improved, the soaking state of the pathological biological tissue is kept for 2-3 hours, and the primary dehydration treatment of the pathological biological tissue is completed;
step three, a solute supplementing mechanism works, solute is filled into the cylinder, so that the concentration of a dehydrating agent in the cylinder reaches a second gradient, the soaking state of the pathological biological tissue is kept for 1-1.5h, and the secondary dehydration treatment of the pathological biological tissue is completed;
and fourthly, filling solute into the cylinder again by the solute supplementing mechanism, so that the concentration of the dehydrating agent in the cylinder reaches a third gradient, the soaking state of the pathological biological tissue is kept for 0.5-1h, and the three-stage dehydration treatment of the pathological biological tissue is completed.
Compared with the prior art, the invention has the beneficial effects that: the invention has novel design, in the dehydration treatment process, the circulating pumping mechanism works to pump the dehydrating agent in the cylinder, and pump a part of the extracted dehydrating agent into the cylinder again through one of the spray heads, so that the dehydrating agent pumped out from the spray heads moves along the tangential direction of the inner wall of the cylinder, vortex is formed in the cylinder, the flow of the dehydrating agent in the cylinder is quickened, the replacement rate of the dehydrating agent on the moisture in the pathological biological tissue is improved, thereby greatly improving the dehydration efficiency, meanwhile, the other part of the dehydrating agent pumped out by the circulating pumping mechanism is pumped up into the cylinder from the bottom of the cylinder again, and the pumped dehydrating agent forms a plurality of liquid columns to generate certain impact force on the pathological biological tissue in the cylinder, so that the pathological biological tissue is in a suspension state in the dehydration treatment process, and further, the problem that the density of the pathological biological tissue is higher than that of the dehydrating agent is sunken in the cylinder and is contacted with the bottom wall of the cylinder is prevented, and the problem of the displacement of the moisture at the contact part of the tissue and the bottom wall of the cylinder is not favorable.
Drawings
FIG. 1 is a schematic diagram of one embodiment of a totally enclosed pathological biological tissue dehydrator;
FIG. 2 is a schematic view of another angular configuration of an embodiment of a totally enclosed pathological biological tissue dehydrator;
FIG. 3 is a schematic view showing the internal structure of a casing of an embodiment of a totally enclosed pathological biological tissue dehydrator;
FIG. 4 is an enlarged view of the structure at A in FIG. 3;
FIG. 5 is an enlarged view of the structure at B in FIG. 3;
FIG. 6 is a schematic diagram of a height adjustment mechanism and a circulation pumping mechanism in one embodiment of a totally enclosed pathological biological tissue dehydrator;
FIG. 7 is a schematic diagram of the connection between the extraction pumping assembly and the elastic structure in one embodiment of the totally enclosed pathological biological tissue dehydrator;
FIG. 8 is a schematic diagram of the mating relationship of the circumferential rotating assembly and the elastic structure in one embodiment of a totally enclosed pathological biological tissue dehydrator;
in the figure: 1. a cabinet body; 2. a cylinder; 3. a cylinder cover; 4. a disc; 5. a water pump; 6. a three-way pipe; 7. an electronic ball valve; 8. a hose; 9. a spray head; 10. a rotating wheel; 11. a connecting piece; 12. a mounting block; 13. a transmission shaft; 14. a bevel gear set; 15. a connecting shaft; 16. a first belt; 17. a case; 18. a piston plate; 19. a first one-way valve; 20. a second one-way valve; 21. a connecting plate; 22. a sliding plate; 23. a protruding block; 24. a column; 25. a slide block; 26. a conduit; 27. a driven plate; 28. a pulley; 29. a threaded sleeve; 30. a screw rod; 31. a gear; 32. an arc-shaped member; 33. a rotating plate; 34. a driving motor; 35. and a second belt.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In addition, an element in the present disclosure may be referred to as being "fixed" or "disposed" on another element or being directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for illustrative purposes only and are not meant to be the only embodiment.
Referring to fig. 1-8, in an embodiment of the present invention, a totally-enclosed pathological biological tissue dehydrator includes a cabinet body 1 and a cylinder 2 disposed in the cabinet body 1 and used for containing a dehydrating agent, a cabinet door (not shown) is disposed at one side of the cabinet body 1, a through hole for placing a pathological biological tissue to be dehydrated into the cylinder 2 is disposed at the top end of the cylinder 2, and a screw cap 3 is disposed on the through hole.
The totally-enclosed pathological biological tissue dehydrator further comprises two spray heads 9 movably arranged in the cylinder 2, the two spray heads 9 are respectively connected with a group of height adjusting mechanisms arranged in the cylinder 2, the two spray heads 9 are connected with a circulating pumping mechanism arranged in the cabinet body 1, a solute supplementing mechanism for pumping solute into the cylinder 2 is further arranged in the cabinet body 1, and the solute supplementing mechanism is further connected with the height adjusting mechanisms.
It is to be understood that:
tissue dehydration is a physical and chemical change process, ethanol is used as a dehydrating agent, is easy to dissolve in water, and can be mixed with water in any proportion. After the tissue is soaked in the ethanol, the water in the tissue is slowly replaced by the ethanol.
The ethanol molecular structural formula and the water molecular structural formula both contain hydroxyl (-OH), the hydroxyl has high hydroxyl bond polarization, the oxygen atom has negative charge, the hydrogen atom has positive charge, and the ethanol molecule and the water molecule can form hydrogen bonds to be combined into an ethanol-water combined molecule;
conventional treatments for tissue dehydration are from low to high concentrations of ethanol, such as 70% ethanol, 80% ethanol, 90% ethanol, 95% ethanol, absolute ethanol i, absolute ethanol ii, in which case the solute added is absolute ethanol to automatically increase the concentration of dehydrating agent in cylinder 2.
When the dehydrating machine is used, a worker opens the cabinet door, unscrews the cylinder cover 3, and introduces a dehydrating agent with a certain concentration into the cylinder 2 through the through hole and places the dehydrating agent into pathological biological tissues to be dehydrated;
the circulation pumping mechanism works to pump the dehydrating agent in the cylinder 2, and pump a part of the extracted dehydrating agent into the cylinder 2 again through one of the spray heads 9, the dehydrating agent pumped out from the spray heads 9 moves along the tangential direction of the inner wall of the cylinder 2, so that vortex is formed in the cylinder 2, the flow of the dehydrating agent in the cylinder 2 is quickened, the replacement rate of the dehydrating agent on the moisture in the pathological biological tissue is improved, and therefore the dehydration efficiency can be greatly improved, meanwhile, the other part of the dehydrating agent pumped out by the circulation pumping mechanism is pumped up into the cylinder 2 from the bottom of the cylinder 2 again, and the pumped dehydrating agent forms a plurality of liquid columns to generate a certain impact force on the pathological biological tissue in the cylinder 2, so that the pathological biological tissue is in a suspension state in the cylinder 2 in the dehydration treatment process, and further, the problem that the pathological biological tissue is sunken in the cylinder 2 because the density of the pathological biological tissue is higher than that of the dehydrating agent is contacted with the bottom wall of the cylinder 2 is prevented, and the problem that the dehydrating agent is not beneficial to the replacement of the moisture of the contact part of the tissue and the bottom wall of the cylinder 2 is solved.
It should be noted that, during the dehydration process, if one of the spray heads 9 continuously pumps the dehydrating agent, a larger recess is generated at the center of the cylinder 2, so that the pathological biological tissue in a suspended state may be exposed above the liquid surface of the dehydrating agent, and a dehydration dead zone is generated, so that the two spray heads 9 are controlled to be alternately conducted by the circulating pumping mechanism during operation, so that two eddy currents with opposite rotation directions are alternately formed in the cylinder 2, and the problem is avoided.
After the pathological biological tissue is soaked in the dehydrating agent for a period of time, the solute supplementing mechanism works to pump the solute into the cylinder 2 so as to ensure that the concentration of the dehydrating agent in the cylinder 2 is increased, and after the solute is pumped into the cylinder 2, the liquid level in the cylinder 2 is increased, if the current height of the spray head 9 is still kept at the current height, under the condition that the power of the circulating pumping mechanism is constant (in the initial stage, the power of the circulating pumping mechanism is not excessively high, a large recess is easily generated at the center of the cylinder 2 at the beginning, and the risk that the pathological biological tissue is damaged is increased due to the excessively high power), eddy current is possibly difficult to form, the accelerating effect on the flowing speed of the dehydrating agent in the cylinder 2 is not obvious, so that the solute supplementing mechanism works and simultaneously drives the height adjusting mechanism to move so that the spray head 9 is driven to rise along with the rising of the liquid level in the cylinder 2, the eddy current can be smoothly formed, and the effective accelerating effect on the flowing speed of the dehydrating agent is realized.
Wherein, it should be pointed out that, since the total amount of liquid in the cylinder 2 increases after each time of pumping the solute into the cylinder 2, the solute pumping mechanism presents an increasing trend each time of pumping the solute in order to ensure an effective and significant increase of the concentration of the dehydrating agent in the cylinder 2;
secondly, in the dehydration treatment process, vortex and liquid column generated by the operation of the circulating pumping mechanism can accelerate the flow speed (molecular diffusion speed) of the dehydrating agent in the cylinder 2 on one hand, improve the dehydration efficiency, and can effectively mix solutes added each time on the other hand, ensure the uniformity of solute distribution in the dehydrating agent, and improve the comprehensiveness of the dehydrating agent on the replacement of moisture in pathological biological tissues.
Referring to fig. 6 again, the circulating pumping mechanism includes a water pump 5 installed in the cabinet 1, a water inlet of the water pump 5 is connected with a conduit 26, the conduit 26 extends into the cylinder 2, a water outlet of the water pump 5 is connected with a three-way pipe 6, and two interfaces on the three-way pipe 6 are respectively connected with a disc 4 and an electronic ball valve 7. The disc 4 is hollow, a plurality of small holes are formed in the upper portion of the disc, and two interfaces on the electronic ball valve 7 are connected with two spray heads 9 through hoses 8 respectively.
When the pathological biological tissue is dehydrated, the water pump 5 works, the dehydrating agent in the cylinder 2 is pumped out through the guide pipe 26, then, the water outlet of the water pump 5 is pumped out through the three-way pipe 6, so that one part of dehydrating agent is pumped into the disc 4 and forms a plurality of liquid columns through small holes at the upper part of the disc 4 to impact the pathological biological tissue, so that the pathological biological tissue is suspended, the dehydrating effect is improved, the other part of dehydrating agent is pumped into the cylinder 2 again through the electronic ball valve 7, the hose 8 and the spray nozzle 9 and moves along the tangential direction of the inner wall of the cylinder 2 to form vortex, the flow speed of the dehydrating agent in the cylinder 2 is accelerated, and in the whole process, the electronic ball valve 7 continuously changes the conduction direction, so that the two spray nozzles 9 alternately pump the dehydrating agent to form two vortex which exist in a staggered way and are opposite in rotation direction.
The height adjusting mechanism comprises two rotating wheels 10 rotatably mounted on the inner wall of the cylinder 2, a connecting piece 11 for connecting the two rotating wheels 10 and an assembling block 12 arranged on one side of the connecting piece 11, the connecting piece 11 is in rolling fit with the two rotating wheels 10, and the spray head 9 is mounted on the assembling block 12. The rotating shaft of one rotating wheel 10 is connected with a transmission shaft 13 rotatably mounted on the outer wall of the cylinder 2 through a bevel gear set 14, the transmission shaft 13 is connected with a connecting shaft 15 rotatably mounted on the outer wall of the cylinder 2 through a first transmission belt 16, and the connecting shaft 15 is connected with the solute supplementing mechanism.
In detail, the bevel gear set 14 includes a first bevel gear installed at one end of the driving shaft 13 and a second bevel gear installed coaxially with the rotating wheel 10, and the second bevel gear is engaged with the first bevel gear.
When the solute supplementing mechanism moves, the connecting shaft 15 is driven to rotate, and then, the connecting shaft 15 drives the transmission shaft 13 to rotate through the first transmission belt 16, the transmission shaft 13 drives the rotating wheel 10 to rotate through the bevel gear set 14, so that the connecting piece 11 moves and drives the assembly block 12 and the spray head 9 to rise, the height of the spray head 9 is adjusted, the spray head 9 rises to rise the liquid level in the cylinder 2, the smooth formation of vortex is ensured under the condition that the power of the water pump 5 is constant, and the effectiveness of accelerating the flow speed of the dehydrating agent in the cylinder 2 is ensured.
Referring again to fig. 4, 5, 7 and 8, the solute replenishment mechanism includes an extracting pumping assembly mounted on the outer wall of the cylinder 2 and a circumferential rotating assembly mounted on the inner wall of the cabinet 1 and cooperating with the extracting pumping structure, and the circumferential rotating assembly is connected with the connecting shaft 15.
The extraction pumping assembly comprises a box body 17 arranged on the outer wall of the cylinder 2, a piston plate 18 arranged in the box body 17 in a sealing sliding manner, and a first check valve 19 and a second check valve 20 arranged on the box body 17. The piston plate 18 is connected with a connecting plate 21, one end of the connecting plate 21 away from the piston plate 18 is connected with an elastic structure arranged on the outer wall of the cylinder 2, the first one-way valve 19 is connected with a solute storage tank arranged outside, and the second one-way valve 20 is connected with the cylinder 2 through a connecting pipe.
When the circumferential rotation assembly moves, the elastic structure is matched with the piston plate 18 to slide back and forth in the box 17 once, firstly, the piston plate 18 slides downwards in the box 17, in the process, the first one-way valve 19 is conducted, the second one-way valve 20 is not conducted, then solute can be pumped into the box 17 through the first one-way valve 19, then, when the piston plate 18 slides upwards in the box 17, the first one-way valve 19 is not conducted, the second one-way valve 20 is conducted, and then, solute in the box 17 can be pumped out into the cylinder 2 through the second one-way valve 20, so that the concentration of the dehydrating agent in the cylinder 2 is improved, and the requirement of dehydration treatment is met.
The elastic structure comprises two upright posts 24 arranged on the outer wall of the cylinder 2 through protruding blocks 23, and a sliding plate 22 which is slidably arranged on the two upright posts 24 and is connected with one end, away from the piston plate 18, of the connecting plate 21, wherein one side, away from the cylinder 2, of the sliding plate 22 is provided with a driven plate 27 matched with the circumferential rotating assembly. And the peripheries of the two upright posts 24 are respectively sleeved with a cylindrical spring, one end of each cylindrical spring is connected with the corresponding protruding block 23, and the other end of each cylindrical spring is connected with the corresponding sliding plate 22.
The circumferential rotation assembly comprises a driving motor 34 arranged on the inner wall of the cabinet body 1, a rotation plate 33 arranged at the tail end of an output shaft of the driving motor 34, and a sliding block 25 arranged on the rotation plate 33 in a sliding manner, and the output shaft of the driving motor 34 is connected with the connecting shaft 15 through a second transmission belt 35. The sliding block 25 is connected with a radial length adjusting structure mounted on the rotating plate 33, and a pulley 28 abutting against the driven plate 27 is rotatably mounted on one side of the sliding block 25 facing the driven plate 27.
When the driving motor 34 works, the driving rotating plate 33 is driven to rotate for one circle, correspondingly, the rotating plate 33 drives the pulley 28 to complete one circle movement, when the pulley 28 rotates for an initial quarter circle, the driven plate 27 drives the sliding plate 22 to slide on the two upright posts 24 towards the protruding blocks 23, correspondingly, the cylindrical springs are compressed, the driven plate 27 drives the piston plate 18 to slide downwards in the box 17 through the connecting plate 21, solute is extracted into the box 17, then, when the pulley 28 rotates for a second quarter circle, the cylindrical springs rebound, and the pulley 28 and the driven plate 27 keep an abutting state, and the sliding plate 22 pushes the piston plate 18 to slide upwards in the box 17 through the connecting plate 21, so that the solute extracted into the box 17 is pumped into the cylinder 2;
finally, in the process of carrying out half-cycle circumferential rotation on the pulley 28, the pulley 28 is separated from the driven plate 27, the diameter length adjusting structure is triggered, and the sliding block 25 is driven to drive the pulley 28 to move along the length direction of the rotating plate 33 (the direction away from the output shaft of the driving motor 34), so that when solute is replenished into the cylinder 2 next time, the track radius of the first half-cycle circumferential movement of the pulley 28 is increased, the stroke amount of the driven plate 27 and the sliding plate 22 for driving the piston plate 18 to reciprocate in the box 17 is increased, namely the solution amount extracted when the piston plate 18 slides downwards and the solute amount pumped into the cylinder 2 when the piston plate 18 slides upwards are increased, and the circulating reciprocating is carried out in such a way, so that the increasing trend of the amount of the solute pumped each time is presented, and the effective and remarkable improvement of the concentration of the dehydrating agent in the cylinder 2 is ensured;
in the above process, the output shaft of the driving motor 34 drives the connecting shaft 15 to rotate through the second transmission belt 35, so that the height of the spray head 9 is changed.
The diameter length adjusting structure comprises a screw rod 30 rotatably mounted on the rotating plate 33 and a threaded sleeve 29 sleeved on the screw rod 30 and in threaded connection with the screw rod 30, and the threaded sleeve 29 is fixed with the sliding block 25. The gear 31 is installed to the one end of lead screw 30, be provided with arc piece 32 on the box 17, arc piece 32 with the central axis coincidence of driving motor 34 output shaft two, just be equipped with on the arc piece 32 with gear 31 complex tooth.
When the driving motor 34 works, the rotating plate 33 drives the gear 31 to perform a circular motion, in the process of performing a circular motion of the second half of the pulley 28, the gear 31 will cooperate with teeth on the arc-shaped member 32 to rotate, and the gear 31 drives the screw rod 30 to rotate, so that the threaded sleeve 29 is in threaded engagement with the screw rod 30 and drives the sliding block 25 and the pulley 28 to move along the length direction of the rotating plate 33 (the direction away from the output shaft of the driving motor 34), so that the stroke amount of the reciprocating motion of the piston plate 18 in the box 17 (namely the amount of solution extracted when the piston plate 18 slides downwards and the amount of solute pumped into the cylinder 2 when the piston plate 18 slides upwards) is increased when the solute is replenished next time.
The application method of the totally-enclosed pathological biological tissue dehydrator comprises the following steps:
firstly, opening a through hole at the top of the cylinder 2, introducing a dehydrating agent with a first gradient into the cylinder 2, putting pathological biological tissues to be dehydrated into the cylinder 2, and closing the through hole;
step two, the circulating pumping mechanism works, vortex and liquid column are generated in the cylinder 2, the flow rate of a dehydrating agent is improved, the soaking state of the pathological biological tissue is kept for 2-3 hours, and the primary dehydration treatment of the pathological biological tissue is completed;
step three, a solute supplementing mechanism works, solute is filled into the cylinder 2, so that the concentration of a dehydrating agent in the cylinder 2 reaches a second gradient, the soaking state of pathological biological tissues is kept for 1-1.5h, and secondary dehydration treatment of the pathological biological tissues is completed;
and fourthly, filling solute into the cylinder 2 again by the solute supplementing mechanism, so that the concentration of the dehydrating agent in the cylinder 2 reaches a third gradient, the soaking state of the pathological biological tissue is maintained for 0.5-1h, and the three-stage dehydration treatment of the pathological biological tissue is completed.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present disclosure describes embodiments, not every embodiment is provided with a separate embodiment, and that this description is provided for clarity only, and that the disclosure is not limited to the embodiments described in detail below, and that the embodiments described in the examples may be combined as appropriate to form other embodiments that will be apparent to those skilled in the art.
Claims (9)
1. The utility model provides a totally closed pathology biological tissue hydroextractor, includes cabinet body (1) and locates the inside of cabinet body (1) is used for splendid attire dehydrating agent's drum (2), its characterized in that still includes:
the two spray heads (9) are movably arranged in the cylinder (2), the two spray heads (9) are respectively connected with a group of height adjusting mechanisms installed in the cylinder (2), the two spray heads (9) are connected with a circulating pumping mechanism installed in the cabinet (1), the circulating pumping mechanism is used for pumping dehydrating agents in the cylinder (2) and pumping the dehydrating agents into the cylinder (2) along the tangential direction of the inner wall of the cylinder (2) through the spray heads (9), and the two spray heads (9) perform dehydrating agent pumping actions in a staggered mode so that two vortex flows with opposite rotation directions are formed in the cylinder (2) in a staggered mode, meanwhile, the dehydrating agents pumped by the circulating pumping mechanism are pumped upwards from the bottom of the cylinder (2), and a plurality of liquid columns are formed in the cylinder (2) so as to promote pathological biological tissues in the cylinder (2) to maintain a suspended state;
the solute supplementing mechanism is arranged in the cabinet body (1) and is used for pumping solute into the cylinder (2), the solute supplementing mechanism gradually increases the amount of the pumped solute into the cabinet body (1) so as to enable the concentration of the dehydrating agent in the cylinder (2) to be changed in an increasing trend, the solute supplementing mechanism is also connected with the height adjusting mechanism, when the solute supplementing mechanism pumps the solute into the cylinder (2), the height adjusting mechanism is caused to drive the spray head (9) to ascend, and therefore vortex can be formed when the spray head (9) executes the dehydrating agent pumping action.
2. The totally-enclosed pathological biological tissue dehydrator according to claim 1, characterized in that the circulating pumping mechanism comprises a water pump (5) installed in the cabinet body (1), a water inlet of the water pump (5) is connected with a guide pipe (26), the guide pipe (26) stretches into the cylinder (2), a water outlet of the water pump (5) is connected with a three-way pipe (6), and two interfaces on the three-way pipe (6) are respectively connected with a disc (4) and an electronic ball valve (7);
the electronic ball valve is characterized in that the disc (4) is hollow, a plurality of small holes are formed in the upper portion of the disc, and two interfaces on the electronic ball valve (7) are connected with two spray heads (9) through hoses (8) respectively.
3. The totally-enclosed pathological biological tissue dehydrator according to claim 2, wherein the height adjusting mechanism comprises two rotating wheels (10) rotatably mounted on the inner wall of the cylinder (2), a connecting piece (11) connecting the two rotating wheels (10) and an assembling block (12) arranged on one side of the connecting piece (11), the connecting piece (11) is in rolling fit with the two rotating wheels (10), and the spray head (9) is mounted on the assembling block (12);
the rotating shaft of one rotating wheel (10) is connected with a transmission shaft (13) rotatably arranged on the outer wall of the cylinder (2) through a bevel gear set (14), the transmission shaft (13) is connected with a connecting shaft (15) rotatably arranged on the outer wall of the cylinder (2) through a first transmission belt (16), and the connecting shaft (15) is connected with the solute supplementing mechanism.
4. A totally enclosed pathological biological tissue dehydrator according to claim 3, characterized in that said solute supplementation mechanism comprises an extraction pumping assembly mounted on the outer wall of said cylinder (2) and a circumferential rotation assembly mounted on the inner wall of said cabinet (1) and cooperating with said extraction pumping structure, and said circumferential rotation assembly is connected with said connection shaft (15).
5. The totally-enclosed pathological biological tissue dehydrator according to claim 4, characterized in that said extraction pumping assembly comprises a tank (17) arranged on the outer wall of said cylinder (2), a piston plate (18) hermetically sliding inside said tank (17), and a first check valve (19) and a second check valve (20) mounted on said tank (17);
the piston plate (18) is connected with a connecting plate (21), one end, away from the piston plate (18), of the connecting plate (21) is connected with an elastic structure arranged on the outer wall of the cylinder (2), the first one-way valve (19) is connected with a solute storage tank arranged outside, and the second one-way valve (20) is connected with the cylinder (2) through a connecting pipe.
6. The totally-enclosed pathological biological tissue dehydrator according to claim 5, characterized in that said elastic structure comprises two uprights (24) arranged on the outer wall of said cylinder (2) by means of protruding blocks (23), a sliding plate (22) slidingly arranged on both said uprights (24) and connected to one end of said connecting plate (21) remote from said piston plate (18), a driven plate (27) cooperating with said circumferential rotating assembly being arranged on the side of said sliding plate (22) facing away from said cylinder (2);
wherein, two the periphery of stand (24) respectively overlaps and is equipped with a cylindricality spring, cylindricality spring's one end is connected protruding piece (23), the other end with sliding plate (22) are connected.
7. The totally-enclosed pathological biological tissue dehydrator according to claim 6, wherein the circumferential rotation assembly comprises a driving motor (34) installed on the inner wall of the cabinet body (1), a rotation plate (33) arranged at the tail end of the output shaft of the driving motor (34) and a sliding block (25) arranged on the rotation plate (33) in a sliding manner, and the output shaft of the driving motor (34) is connected with the connecting shaft (15) through a second transmission belt (35);
the sliding block (25) is connected with a radial length adjusting structure arranged on the rotating plate (33), and a pulley (28) abutted with the driven plate (27) is rotatably arranged on one side of the sliding block (25) facing the driven plate (27).
8. The totally-enclosed pathological biological tissue dehydrator according to claim 7, characterized in that said diameter-length adjusting structure comprises a screw rod (30) rotatably mounted on said rotating plate (33) and a threaded sleeve (29) sleeved on said screw rod (30) and screwed with said screw rod (30), said threaded sleeve (29) being fixed with said slider (25);
the novel screw rod comprises a screw rod body (30), and is characterized in that a gear (31) is arranged at one end of the screw rod (30), an arc-shaped piece (32) is arranged on the box body (17), the central axes of the arc-shaped piece (32) and the output shaft of the driving motor (34) are coincident, and teeth matched with the gear (31) are arranged on the arc-shaped piece (32).
9. A method of using the totally enclosed pathological biological tissue dehydrator according to claim 1, comprising the steps of:
firstly, opening a through hole at the top of the cylinder (2), introducing a dehydrating agent with a first gradient into the cylinder (2), putting pathological biological tissues to be dehydrated into the cylinder (2), and closing the through hole;
step two, the circulating pumping mechanism works, vortex and liquid column are generated in the cylinder (2), the flow rate of a dehydrating agent is improved, the soaking state of the pathological biological tissue is kept for 2-3 hours, and the primary dehydration treatment of the pathological biological tissue is completed;
step three, a solute supplementing mechanism works, solute is filled into the cylinder (2), so that the concentration of a dehydrating agent in the cylinder (2) reaches a second gradient, the soaking state of the pathological biological tissue is kept for 1-1.5h, and the secondary dehydration treatment of the pathological biological tissue is completed;
fourthly, the solute supplementing mechanism fills solute into the cylinder (2) again, so that the concentration of the dehydrating agent in the cylinder (2) reaches a third gradient, the soaking state of the pathological biological tissue is kept for 0.5-1h, and the three-stage dehydration treatment of the pathological biological tissue is completed.
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| CN202310293610.4A CN116296682A (en) | 2023-03-23 | 2023-03-23 | Totally-enclosed pathological biological tissue dehydrator and application method thereof |
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| CN202310293610.4A CN116296682A (en) | 2023-03-23 | 2023-03-23 | Totally-enclosed pathological biological tissue dehydrator and application method thereof |
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