CN116267922B - Use of photosynthesis inhibiting herbicides as safeners for chemical androgens - Google Patents
Use of photosynthesis inhibiting herbicides as safeners for chemical androgens Download PDFInfo
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- CN116267922B CN116267922B CN202310217290.4A CN202310217290A CN116267922B CN 116267922 B CN116267922 B CN 116267922B CN 202310217290 A CN202310217290 A CN 202310217290A CN 116267922 B CN116267922 B CN 116267922B
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- inhibiting
- methyl
- acetolactate
- tribenuron
- herbicide
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- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
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Abstract
The invention discloses an application of herbicide for inhibiting photosynthesis as safener and/or protectant of chemical emasculation, which is used for treating emasculation target plants in early bud development; the safener and/or the safener can be used for relieving the inhibition effect of the chemical emasculator on plant growth, inflorescence elongation, flower organ size and pistil setting performance when the dosage of the chemical emasculator is excessive, and simultaneously, the emasculation effect of the chemical emasculator on stamen is maintained; the female parent becomes more receptive to pollen production hybrids of the male parent plant. The safener and/or the safener allow the application dosage of the emasculation agent to be properly increased to strengthen the emasculation effect, and solve the defect that the field treatment effect is easy to swing between phytotoxicity and invalidity due to the narrow safety window of the chemical emasculation agent, so that the hybridization rate of the hybrid seeds is improved on the premise of not reducing the seed yield, and the safener have huge market application prospect.
Description
Technical Field
The invention belongs to the fields of crop breeding and seed production, relates to a plant fertility chemical regulation technology, and in particular relates to application of a herbicide for inhibiting photosynthesis as a safener (or a protectant) of an acetolactate/hydroxy acid synthetase inhibitor type chemical emasculation agent.
Background
The use of plant heterosis is an important breeding strategy to increase its biological or economic yield. Modern breeding science is increasingly large in mass innovation and breeding material transformation, traditional heterosis utilization needs more than 6-10 generations to transform parents into sterile lines or restorer lines, long work becomes a speed-limiting step of breeding, and breeders are urgent to need a short and flat hybrid seed production mode. In theory, chemical emasculation should be the simplest method of utilizing heterosis, and ideal chemical emasculation technology allows the direct induction of male sterility by chemical treatment of either a certain plant germplasm, line, or variety (chemical emasculation or chemical cross Chemical hybridizing agent), as a female parent, to receive pollen from another germplasm, line, or variety as a male parent, producing hybrids. However, in practice, most of the chemical emasculation technologies invented at present have unstable application effects, the hybridization rate (genetic purity) of seeds for large-area commercial seed production is difficult to reach the corresponding industry standard requirements, and the seed production failure risk is extremely high.
Herbicides that inhibit synthesis of branched-chain amino acids BCAAs (leucine Leu, isoleucine Ile, valine Val) by target acetolactate/hydroxy acid acetosynthetase (ALS/AHAS) are numerous and can be largely classified into 5 classes, such as Sulfonylurea (SU), imidazolinone (IM), triazolopyrimidine sulfonamide (TP), pyrimidine salicylic acid (PB), sulfonylaminocarbonyl triazolinone (SCT), and the like. In the study, it was found that part of the herbicides in sulfonylurea and imidazolinones have a high efficiency in emasculation of crucifers when applied at sub-lethal doses (near lethal doses) [ in Chengyu et al ]; the characteristics and mechanisms of action of phytochemical hybridization agents, northwest national university of agriculture and forestry science and technology doctor paper, 2009; yu CY, et al Exposure to trace amounts of sulfonylurea herbicide tribenuron-methyl causes male sterility in 17species or subspecies of cruciferous plants.BMC Plant Biology.2017, 17:95. Examples of such herbicides that can be used as androgens are sulfourea-like tribenuron-methyl (abbreviated TBM in english) [ Yu C, et al, induced male sterility in Brassica napus l by a sulfonylurea herbicide, tribenuron-methyl, plant broadcasting, 2006, 125 (1): 61-64 ], amidosulfuron [ for use in the preparation of brassica phytochemical hybridizer, ZL200610042886.1 ], chlorsulfuron, metsulfuron, bensulfuron, pyrazosulfuron [ for use in the preparation of phytochemical hybridizer, characteristic and mechanism of action of phytochemical hybridizer, doctor paper in northwest agriculture and forestry university, 2009, imidazolinone-imazethapyr [ for use in the preparation of brassica phytochemical hybridizer, etc. ], compound (RS) -5-ethyl-2- (4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl) nicotinic acid and ammonium salt thereof for use as phytochemical hybridizer ZL 200810231884.6. Through experiments, the tribenuron-methyl is found to have a emasculation effect on certain broadleaf plants such as watermelons (Jiang Liyuan. Chemical emasculation agent applied to watermelons is primarily screened and researched, the national institute of science and technology of northwest agriculture and forestry is in 2016), pansy (Hu Huirong and the like; pansy chemical emasculation agent composition, preparation method and application, chinese patent application (publication number: CN103539539A, application number: 2013104763892) and the like, wherein the chemical emasculation breeding of rape is greatly progressed in more than 10 years, the technical threshold of rape breeding is greatly reduced based on the chemical emasculation two-line method of the high-efficiency emasculation agent, and the explosion of commercial breeding is promoted.
However, breeding specialists have found that this seemingly simple and practical breeding technique still has serious technical drawbacks. Taking rape as an example, the true hybridization rate of most commercially available rape chemical emasculation two-line hybrid seeds is not high, only about 50-80%, and is lower than the national standard secondary seed requirement (GB 4407.2-2008) of 85%, because the female parent is not completely emasculated and a large number of selfs are mixed into the offspring during seed production. The hybrid seeds cannot be used for a long time and unfortunately because growers lack expertise of breeders, the female parents of chemical male-killing seed production hybrid seeds cannot be identified in a shape similar to that of heritable male sterile female parents in a pattern of flowers, otherwise, poor consistency of commercial popularization seed hybrid seeds of chemical male-killing two-line hybrid seeds can be caused, due hybrid vigor of original varieties during breeding or registration is lacked, the hybrid seeds belong to low-purity pseudo-inferior seeds, and huge industrial hidden trouble is brought.
The main technical limitation factor causing the low purity of the chemical emasculation hybrid is that target plants, especially brassica crops of cruciferae such as rape, cabbage, mustard, cabbage and the like, are very sensitive to sulfonylurea emasculation agents such as tribenuron-methyl, amidosulfuron and the like, the dosage interval from ineffective to emasculation to phytotoxicity (i.e. the "emasculation safety window", similar to the therapeutic window of pharmaceutics-the difference between the minimum effective dose and the poisoning dose) is narrow, and the narrower the window indicates that the drug has poorer safety. Taking a common technical method of rape of the applicant as an example, taking a tribenuron-methyl spraying amount of 0.3mg/L of 2ml of each plant (suitable object is a medium seedling with a bud development plant height of about 50 cm) as a standard, slightly undershot drug receiving amount (< 1 ml) or too large rape seedling nutrition can cause the drop of the emasculation rate, and slightly more drug receiving amount (> 3.5 ml) or weaker seedling can cause the phytotoxicity. Plant stem node and inflorescence section with serious phytotoxicity can not be elongated, young leaves and flower buds are yellowing and purple, flower organs are reduced, and seed production yield is obviously reduced when serious [ in Chengyu and the like ], evaluation of male sterility effect of rape induced by amino acid synthesis inhibitor herbicides is performed, crop theory report, 2014, 40 (2): 264-272; yu Cheng-Yu, et al Sublihal application of various sulfonylurea and imidazolinone herbicides favors outcrossing and hybrid seed production in oilseed rope BMC Plant Biology,2020, 20:69.
Most of the current brassica plant androgens contain sulfonylurea or imidazolinone androgens such as tribenuron-methyl. The spray effect is obviously interfered by the humidity, temperature, blowing, genetic background of female parent, development progress, growth uniformity, leaf wax powder, leaf area, bud development concentration degree and the like (in the doctor paper of northwest agriculture and forestry science and technology university, 2009), and the spray dosage cannot be accurately adjusted according to the field condition. In order to solve the technical bottleneck that the dosage window between poison and ineffective is narrow and difficult to accurately control, the safe dosage form of the androgens with higher efficiency and wider dosage range needs to be researched. For this reason, breeders have attempted to add nutrients (such as urea, sugars, boron fertilizers) to androgens, or growth regulating substances such as paclobutrazol, gibberellins, brassinolide, or adhesion promoters (esterified vegetable oils, silicone adjuvants, etc.) to increase the effective uptake. Or different androgens are mixed to expand the use range of the androgens, so as to improve the stability of the androgenic effect. For example, chinese patent application (publication No. CN108719303A, chen Jin, etc. A cruciferous crop chemical emasculation composition WP and method of use thereof) is a method of mixing bensulfuron-methyl and paclobutrazol. The compound chemical hybridization agent provided by Chinese patent application (publication No. CN101919399A, liu Xuanxia, etc. A compound chemical hybridization agent composition and application thereof, application No. 2010102042388) contains tribenuron-methyl, thifensulfuron methyl, boric fertilizer, dispersing agent and soluble starch. Chinese patent application (publication No. CN103518758A, jiang Liangcai, etc., a preparation method of novel cabbage type rape compound chemical emasculation agent and application thereof. Application No. 2012102382196) discloses an emasculation agent containing tribenuron-methyl and pyrazosulfuron-ethyl. The emasculation agent disclosed in Chinese patent application (publication No. CN103539539A, hu Huirong, etc.), pansy chemical emasculation agent composition, preparation method and application, application No. 2013104763892 is composed of tribenuron-methyl, urea, gibberellin, washing powder and water. However, these formulations for fine tuning sulfonylurea androgens have had limited practical application in seed production as tested by practice for many years. If the toxicity generation route of the androgens is not fundamentally interfered, the problem of narrow safety window of the androgens is difficult to solve. The idea of expanding the safety window is to alleviate or eliminate the toxic side effects of the androgens on non-stamen organs without interfering with their androgenic effect, so that the development of a corresponding Safener (Safener) for the androgens is required, but no research has been made in the literature to date on these problems.
Safeners for herbicides, also known as antidotes (antidotes) or safeners (safeners), are selective protection of crops between application and weed, which is relatively easy to achieve. The safeners or safeners of the emasculation agents are different, so that the stamens, pistils and other organs of the same crop are selectively protected, the action mechanism of the safeners and the safeners of the herbicide are greatly different, and the implementation difficulty is also great. At present, the detoxification mode of the special application field which is only concerned by the breeding professional technician is not focused on the pesticide research and development field.
As for the action mechanism of safeners of herbicides, the former proposes different theoretical mechanisms of absorption transport, target competition, non-target metabolic detoxification and the like. However, the former two methods can reduce the herbicidal effect, so that the actual implementation is not feasible, and the safety agent is widely accepted at the present stage to influence the metabolic detoxification of the herbicide in the crop protection bodies, but no theory exists so far [ Hu Lifeng and the like ] the research on the action mechanism of the herbicide safety agent is advanced, and the pesticide science report, 2017, 19 (2): 152-161 ]. The main cytochromes involved in metabolic detoxification and non-target resistance of plants to herbicides are CYP450s, GSTs, UGTs, GSH and the like. It is known that cross-resistance exists for some different types of herbicides, and that such non-target cross-resistance may result from genetic variation at the CYP450s, GSTs, UGTs, GSH isosite leading to enhanced metabolic detoxification of the different herbicides.
The mixing of different herbicides is a common technique at present, aiming at avoiding the generation of resistance, enlarging the weeding effect and the weeding range (weeding spectrum). For example, herbicides such as chlortoluron and isoproturon, which are substituted for urea, act on D1 protein of photosystem PSII as an action target, and inhibit photosynthesis of plants. Is commonly used for preventing and killing annual grassy weeds such as myrtle, hard grass, glory grass, bluegrass, wild oat and the like in wheat fields, and broadleaf weeds such as shepherd's purse, herba polygoni avicularis, chickweed and amaranth and the like. However, the substituted urea herbicide is gradually reduced and singly used due to the high residue problem, and is commonly used with other types of herbicides including sulfonylurea, such as isoproturon and bensulfuron-methyl (Sun Xuemei. An isoproturon and bensulfuron-methyl compound herbicide, chinese patent application, application number: CN 201010535586), mesosulfuron, pyroxsulam, flucarbazone, cycloflucarbazone and the like, and the like are compounded (pesticide quick-action information network: wheat Tian Neng is subjected to closed weeding by bensulfuron-methyl, http:// www.agroinfo.com.cn/other_detail 5944. Html).
There are 20 herbicides that have been commercially used at present and target plant photosynthetic systems. Among them, herbicides targeting photosynthetic system II (PSII) include:
Substituted ureas (e.g., fesulfuron, buthiuron, methosulfuron, chlorazuron, chlormeuron, isoproturon, diuron, chloruron, bromuron, clofentezine, linuron, tribenuron-methyl, chlorbromuron);
triazobenzenes (e.g., atrazine, simazine, prometryn, terbutryn, ametryn, cyanazine, simetryn, ametryn, prometryn, ipratropium, flubenazolin);
triazinones (e.g., oxazin, hexazinone, oxazinone);
nitriles (e.g., bromoxynil octanoate, bromophenol oxime, ioxynil);
amides (e.g., propanil);
uracil (e.g., triclopyr, terfenacet);
pyridazinones (chloroxamine);
carbamates (e.g., betanin, betalain);
triazolinones (amicarbazone);
benzothiadiazinones (bentazone);
and the like.
Herbicides targeting plant photosynthetic system I inhibitors currently include bipyridines (e.g., paraquat, diquat) and the like. At present, the application of the targeted plant photosynthesis inhibiting herbicides in combination with other herbicides is limited to enlarging the herbicide killing spectrum of the herbicides, and the substituted urea herbicides in combination have the effect that the herbicides are not protective agents and are not consciously used as detoxification protective agents of crops to be sprayed. Chinese patent application (publication No. CN 101884335A) discloses a use method of mixing isoproturon and bensulfuron-methyl serving as a androgens according to a ratio of 100:1 and spraying the mixture according to a concentration of 0.1g/L (Zhou Xuan and the like, a chemical androgens composition for cruciferous crops and an application method thereof, patent application No. 2010102347066, legal state: 2013.10.23 application published as withdrawal), but the role and the effect of isoproturon in a compound androgens are not disclosed in the application, and particularly whether the isoproturon acts as an antagonistic or protective agent for bensulfuron-methyl is not described and illustrated at all. Therefore, the application is probably only extended application of the common herbicide bensulfuron-isoproturon compounded herbicide in the market, and is used as an accidentally obtained experience, and does not relate to the application as a safener.
There are two sets of approaches in plants that conservatively regulate changes in nutrition and energy levels: the TOR Kinase (Target of Rapamycin, rapamycin target) complex is the main regulator of amino acid abundant status receptors and protein synthesis, and SnRK1 Kinase (cross non-interfering 1-linked Kinase 1) senses sugar supply [ paragraph(s) ] sugar signal regulation of plant vital activity and its synergistic regulation with auxin. Shanghai agricultural journal 2016,32 (1): 106-112 ]. GCN2 kinase (general control nonrepressed 2) determines the lack of amino acids by sensing tRNA idle load, and its mediated phosphorylation of eukaryotic translation initiation factor eif2α is part of the cellular homeostatic mechanism of plants in stress states such as dysregulated protein homeostasis, which is regulated by TOR. The amino acid homeostasis regulated by "GCN 2-TOR-autophagy" was also found to contribute to the tolerance of the herbicide tribenuron-methyl [ Zhao L, et al Autophagy contributes to sulfonylurea herbicide tolerance via GCN2-independent regulation of amino acid homeostasis. Autophagy.2018, 14 (4): 702-714 ].
In recent years, there have been few studies on the phenomenon that there may be interference between the effect of a photosynthesis inhibiting herbicide and other herbicides on TOR, reactive oxygen species ROS, etc., but there has been no special and careful study on the effect of such interference, which is limited to the study on individual physiological effects of plants, and no study on herbicidal effects. An investigation with unicellular model plant chlamydomonas found an indirect link between ALS inhibition and PSII inhibition: PSII-inhibiting herbicide Diuron (DCMU) treatment reduces the photosynthetic Calvin-Benson-Bassham cycle efficiency, resulting in reduced levels of branched-chain amino acids BCAs and the like, and then affects growth-promoting factor TOR kinase activity [ Mallin-Ponce MJ.et al photosynthetic assimilation of CO2 regulatory TOR activity, proc Natl Acad Sci USA.2022, 119 (2): e2115261119 ]. It has also been found that chlorsulfuron activates GCN2 by chloroplast Reactive Oxygen Species (ROS), and blocking electron transfer of the plastid quinone PQ/PQH2 with the photo-synthetic inhibitor diuron DCMU or the compound DBMIB inhibits chlorsulfuron-induced ROS and GCN2 kinase [ Lokdarshi A., et al light Activates the Translational Regulatory Kinase GCN2 via Reactive Oxygen Species Emanating from the chlorine Plant Cell 2020, 32 (4): 1161-1178 ].
When tribenuron-methyl TBM is used as a emasculation agent, the effect on sensitive plants such as canola may also be involved in these pathways. The applicant could therefore predict that inhibition of the PSII system by diuron or its analogues, by reference to the metabolic regulation indicated in these several documents, might have a certain antagonism towards ALS-inhibiting herbicides.
Disclosure of Invention
The invention aims to provide a safener (or a safener) used in combination with an acetolactate/hydroxy acid synthetase inhibitory chemical emasculation agent, which is used for improving the stability and the safety of emasculation effect.
In order to achieve the above task, the present invention adopts the following technical solutions:
use of a photosynthesis inhibiting herbicide as safener and/or protectant component of an acetyl/hydroxy acid lactic acid synthase inhibiting type of chemical androgens.
And is implemented according to the following method:
at the same time, or for a suitable period of time before, or after, the application of a chemical emasculation agent (the main active ingredient being acetolactate/hydroxyacid synthase-inhibiting compound) to the target plant to be emasculated (i.e., the female parent), a herbicide whose main ingredient is photosynthesis PSII-inhibiting is also applied to the female parent plant to be emasculated as a safener (or protector) treatment. The method is used for relieving the inhibition of the nutrition growth, inflorescence elongation, flower set size, chloroplast development and pistil setting performance of a female parent of a male sterile plant to be treated when the acetolactate/hydroxy acid synthetase inhibition type chemical emasculation agent is excessive, and simultaneously keeping the emasculation effect of the emasculation agent, so that the female parent of a target plant receives pollen of a male parent to produce seeds of hybrid seeds; the safener can be used to treat the female parent of the target plant with a greatly increased dose of chemical emasculation, with significantly less phytotoxicity to the vegetative organs and pistils than emasculation without the application of these safeners. So that the pistil bearing capacity can be improved on the premise of ensuring higher emasculation rate and hybridization rate of the hybrid seeds, and higher seed production yield can be obtained.
The main component is a photosynthesis PSII inhibition type herbicide, and targets are selected from non-chloruron, buthiuron, methosulfuron, chlortoluron, fluometuron, isoproturon, diuron, chloruron, bromoxynil, clodinafop-propargyl, cycloxynil, linuron, tribenuron, atrazine, simazine, prometryn, terbuthylazine, ametryn, cyanazine, moxidec, ametryn, prometryn, isoproturon, fluroxypyr, oxazin, hexazinone, oxazidone, propanil, bromoxynil, ioxynil, herbicidal, terbutachlor, chloroxadiazon, bentazone, and the like; one or more than 2 of these compounds may be used; preferably, common herbicides such as isoproturon, diuron, metribuzin, atrazine and bromoxynil are adopted; the upper dosage limit is used for slightly inhibiting the leaf development of the target plant for emasculation, and the leaf can be slightly yellow within 1-10 days without atrophy or drying out;
the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent can be a mixture of one or more than 2 compounds which target acetolactate/hydroxy acid synthetase and are commonly used as herbicide. The main components are tribenuron-methyl, metsulfuron-methyl, chlorsulfuron, trifloxysulfuron, sulfosulfuron, flusulfamuron, amidosulfuron, nicosulfuron, pyrazosulfuron-ethyl, halosulfuron-methyl, sulfosulfuron-methyl, primisulfuron-methyl, chlorimuron-ethyl, thifensulfuron-methyl, iodosulfuron-methyl, flucarbazone-methyl, imazethapyr (imazethapyr), imazethapyr, methyldisulfuron, ethoxysulfuron, epoxysulfuron-methyl, amidosulfuron-methyl, tetrazolsulfuron-methyl, bensulfuron-methyl, triflusulfuron-methyl, imidazolsulfuron-methyl, cyclosulfamuron-methyl, ether sulfuron-methyl, ether tribenuron-methyl and the like. These compounds are currently commercially used as herbicides. Preferably, compounds with relatively more stable androgenic efficiency such as tribenuron-methyl, amidosulfuron, chlorsulfuron, trifloxysulfuron, sulfosulfuron and the like are used as safeners/protectants; in practice, the dosage of the composition can be slightly increased by 0.2 to 1 times compared with the normal dosage of the composition;
The appropriate timing of the safener treatment of the target plant to be emasculated is to mix or separately treat the emasculating agent and safener/safener separately, either simultaneously with or before or within a suitable period of 0 to 72 hours after the application of the chemical emasculating agent to the target plant to be emasculated. Preferably, the safener/protectant and the emasculation agent are mixed together (i.e., the pesticide is compounded or mixed) during the spraying treatment to treat the target plant to be emasculated, so as to reduce the field workload and ensure that the safener/protectant timely protects pistils and the like.
The androgen and safener/safener treatments are typically spray-type, but may also be applied, dipped, injected, buried, root irrigation (drip irrigation or infiltrating irrigation), etc., as desired.
Male sterile target plants to be emasculated refer to all plants that are rendered male sterile by acetolactate/hydroxy acid synthase-inhibiting androgens, including, but not limited to, cruciferous plants that have a high sensitivity to herbicides such as sulfonylurea, e.g., rape, cabbage, mustard, egyptian mustard, black mustard, radish, white mustard, arabidopsis, zhugan, chikungunya, pennycress, camelina, peppers, indian rorhiza, violet, cinquefoil, sugar mustard, and the like. The plants can also be watermelon, melon, gourd, etc. of Cucurbitaceae, and pansy, etc.
The main components are photosynthesis inhibiting herbicide and chemical emasculation agent with acetolactate/hydroxy acid synthetase inhibiting compound as main active components, and may also contain other minor components, namely pesticide adjuvant (filler or carrier, solvent, emulsifier, wetting agent, dispersant, adhesive, penetrating agent, etc.); conventional growth regulating substances (e.g., paclobutrazol, uniconazole, brassinolide, etc.) and nutrients (e.g., urea, sugar, amino acids, boron, vitamin C, vitamin E, etc.) as auxiliary ingredients enhance the efficacy.
The safener and/or protectant is used, and the optimum period for the emasculation treatment of the target plant is in the bud phase. Taking brassica rape, cabbage and mustard as examples, the bud-developing period of flowering plants in spring after overwintering is to slightly separate the top few heart leaves of the stems of the plants, and the inflorescence and a large number of buds can be seen by naked eyes. The cruciferous plant is of infinite inflorescence type, has long flowering period and can last for more than 2 weeks to 6 weeks. And the biomass of flowering plants of bolting becomes larger and larger, so that the tolerance to the emasculation agent is enhanced.
If the spraying period is too early, the efficacy of the emasculation agent is weakened in the duration of the flowering period because the emasculation agent is decomposed along with metabolic detoxification, and the second and even third emasculation agent treatment is needed to be supplemented;
If the spraying is too late, the fertility of the developed buds at the earlier stage is basically normal, early buds are required to be removed by picking and topping, and the workload is increased.
Although the oxaziclomefone, isoproturon and the like have no effective emasculation effect on target plants, the safener and/or the safener can play an obvious protection role on the premise of not reducing the emasculation effect of the emasculation agent on stamens, and the obvious technical effects are that:
(1) The aging symptoms such as long-time yellowing of buds and young leaves, anthocyanin accumulation and the like after the tribenuron-methyl TBM treatment are reduced, the chloroplast structure is protected, and the buds are relatively normal green;
(2) The inhibition of TBM and the like on inflorescence elongation (mitosis and cell growth) is relieved, pistils are protected, and pollination fecundity is improved.
Drawings
FIG. 1 is a comparative picture of leaf blades of two treated oilseed rape compounded with bensulfuron-methyl Long Shandu, bensulfuron-methyl and isoproturon; wherein, the (A) graph is that tribenuron-methyl is treated independently, and young leaves of rape are yellow and flower buds fade; (B) The figure shows that the combination treatment of tribenuron-methyl and isoproturon causes the leaves to be yellow but the degree is light, and the green color of the flower buds is normal.
Fig. 2 is a picture of comparison of an electron microscope image of chloroplasts of a rape and a control treated by tribenuron-methyl alone and by compounding tribenuron-methyl and isoproturon, wherein (A) is chloroplast of a normal rape, (B) is a picture of a base grain layer of the chloroplast which is not formed by the independent treatment of tribenuron-methyl, and is blurred in overall structure, and (C) is a picture of the combined treatment of tribenuron-methyl and isoproturon, so that structural damage to the chloroplast is reduced, and the structure is clearer.
Fig. 3 is an inflorescence comparison of single-treatment of tribenuron-methyl and mixed-treatment of tribenuron-methyl and isoproturon, wherein (A) is a picture of single-treatment of tribenuron-methyl, inflorescence is difficult to elongate, flower buds are empty, petals are difficult to open, and (B) is a picture of combined treatment of tribenuron-methyl and isoproturon, so that phytotoxicity at inflorescence parts can be remarkably reduced, inflorescence is normally elongated, flower axis colors are not purple any more, flower buds are large, and petals are flat.
Fig. 4 is a picture comparing the pollen acetate magenta staining of a rape treated by tribenuron-methyl alone and by blending tribenuron-methyl and isoproturon with a control, wherein (a) is a normal rape, (B) is a tribenuron-methyl treatment, a pollen abortion deformity, and (C) is a combined treatment of tribenuron-methyl and isoproturon, which also can inhibit pollen development, a pollen grain deformity, a lighter staining, and little or no content.
The present invention will be described in further detail with reference to the accompanying drawings and examples given by the inventors.
Detailed Description
During the process of large-scale screening by the mixed pesticide spraying test of herbicide and chemical androgens, the inventor of the applicant unexpectedly found that metribuzin, isoproturon and the like targeting PSII core D1 protein of a photosynthesis system have obvious relieving/antagonism on physiological toxicity of ALS/AHAS inhibition type androgens (even comprising lower herbicide dosage treatment). This is a phenomenon which has not been examined and analyzed by the person skilled in the art, and has unexpected effects. There is currently no literature on the intrinsic scientific principles of this bio-chemical regulatory phenomenon that are of great industrial application value and attempt to explain it.
The application and implementation method of the photosynthetic inhibiting herbicide serving as a Safener/protective agent (Safener) of the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent have the main advantages of combining high efficiency emasculation on stamens and protection on pistils and nutrient growth, thus solving the defects that the emasculation safety window of the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent (hereinafter referred to as an emasculation agent) is narrow and the treatment effect swings between phytotoxicity and ineffectiveness. The emasculation effect is ensured by slightly increasing the dosage of the emasculation agent, the seed production purity is improved, and the seed production risk of the hybrid seeds is reduced; and the safener/protectant is used to antagonize the growth of nutrients other than stamens and the development of whole inflorescences and pistils, ensuring sufficient setting ability and seed yield.
The method is implemented by the following steps:
simultaneously, or before or within 0-72 hours after the application of the acetolactate/hydroxy acid synthase-inhibiting type chemical emasculation agent to the female parent of the target plant to be emasculated, the female parent is treated with a safener whose main component is a photosynthetic PSII-inhibiting herbicide to relieve the suppression of the vegetative growth, inflorescence elongation, floral size, chloroplast development, pistil setting performance of the female parent of the treated male-sterile plant when the acetolactate/hydroxy acid synthase-inhibiting chemical emasculation agent is excessive, while maintaining the emasculation effect of the emasculation agent such that the female parent of the target plant receives pollen to produce seeds of the hybrid;
The acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is one or more than 2 mixtures of acetolactate/hydroxy acid synthetases as targets, and the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is: the dosage of the tribenuron-methyl, the metsulfuron-methyl, the chlorsulfuron-methyl, the trifloxysulfuron, the sulfosulfuron-methyl, the flusulfamuron-methyl, the amidosulfuron-methyl, the nicosulfuron, the pyrazosulfuron-ethyl, the halosulfuron-methyl, the chlorimuron-ethyl, the thifensulfuron-methyl, the iodosulfuron-methyl, the flucarbazone-methyl, the imazethapyr (imazethapyr), the imazethapyr, the mesosulfuron-methyl, the ethoxysulfuron-methyl, the epoxy azosulfuron-methyl, the foramsulfuron-methyl, the tetrazole-methyl, the tribenuron-methyl, the trifloxysulfuron, the cyclosulfamuron, the cinosulfuron-methyl and the cinosulfuron-methyl can be slightly increased by 0.2 to 1 time compared with the dosage of the normal emamectin-benzoate;
the main component is one or more than 2 of compounds with a photosynthetic PSII inhibition type herbicide as an action target point of acetolactate/hydroxy acid synthetase, and the compounds are as follows: the upper dosage of the compositions is limited to slightly inhibit leaf development of a target plant to be emamectin benzoate, buthiuron, methouron, meturon, chloruron, chlormeuron, diuron, chloruron, bromoxynil, clodinafop-propargyl, cyclouron, linuron, tribenuron, atrazine, simazine, prometryn, terbuthylazine, amethomoxine, primisulfuron, prometryn, flubenuron, metribuzin, hexazinone, oxazinone, benzodiazuron, propanil, bromoxynil, bromfenaoxime, ioxynil, triclopyr, terbuthylazine, chlorchlorphenamine, betanin, amicarbazone, bentazone or pyridate, and the use of the compositions to slightly inhibit leaf development of a target plant to be emamectin benzoate, slightly yellow within 1-10 days without atrophy or dry out.
In the above-mentioned photosynthesis inhibiting herbicide as Safener (Safener)/Safener (Safener) of acetolactate/hydroxyacid synthase inhibitory chemical emasculation agent (hereinafter referred to as Safener/Safener), conventional agricultural adjuvants, agricultural growth regulating substances and agricultural nutrients may be added; wherein the conventional pesticide auxiliary agent is a filler, a carrier, a solvent, an emulsifier, a wetting agent, a dispersing agent, an adhesive or a penetrating agent; the agricultural growth regulating substance is paclobutrazol, uniconazole or brassinolide; the agricultural nutrients are urea, sugar, amino acid, boron or vitamins.
The safener/protectant is preferably applied simultaneously with the acetolactate/hydroxy acid synthase-inhibiting chemical androgens, i.e., by mixing the acetolactate/hydroxy acid synthase-inhibiting chemical androgens with the safener/protectant in respective appropriate doses such that the safener/protectant synergistically protects the acetolactate/hydroxy acid synthase-inhibiting chemical androgens.
The specific implementation mode is as follows:
the dosage of 1 or more than 2 photosynthetic PSII inhibiting herbicide formulations or other plant absorbable forms is referred to the normal herbicide usage, preferably the dosage which does not cause significant growth inhibition of the treated plants, at most slightly yellowing the leaves. For example, isoproturon and metribuzin are suitably present in a concentration of 0.1 to 2g/L, preferably 0.3 to 0.9g/L. The specific concentration is determined according to the average plant receiving amount of the plants and the plant nutrient body size in the treatment modes such as spraying.
The concentration or dosage of the primary active ingredient may be slightly greater than the optimum concentration or dosage of the androgens alone by formulating the acetolactate/hydroxy acid synthase-inhibiting chemical androgens in a suitable solution or other plant-absorbable form.
The two substances (photosynthetic PSII inhibiting herbicide and acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent) are treated successively or in mixture to female parent plant needing emasculation.
In this example, the target plants to be emasculated are all plants that can be induced to be male sterile with acetolactate/hydroxy acid synthase-inhibiting emasculating agents, including but not limited to cruciferous plants that have a high sensitivity to herbicides such as sulfonylurea, which are rape, cabbage, mustard, egyptian mustard, black mustard, radish, white mustard, arabidopsis thaliana, zhugar, arabidopsis, chikungunya, tilia, pennycress, camelina, pepperweed, robinia rorhiza, violet, cinquefoil or sugar mustard, or watermelons, melons, cucurbits, etc., of Cucurbitaceae, and pansy. Through the detection of the inventor, the broad-leaved plants are relatively sensitive to most of sulfonylurea and imidazolinone androgens such as tribenuron-methyl, amidosulfuron and imazethapyr, and the like, and can induce high male sterility through the androgens.
The most common treatment method is spraying the surface of the plant, or can adopt methods of liquid medicine infiltration, irrigation and the like for treatment.
In the implementation process, the staicicide and the safener/safener can be treated before and after the treatment in a plurality of times, and the shorter the interval time is, the better the interval time is, and the less than 3 days are needed. Taking spray treatment as an example, after the first medicament is treated, the second medicament can be sprayed after observing that the foliar mist drops are dried, the interval time can be from about half an hour to several hours or even 3 days, and the protection effect is poor if the interval time is too long. The preferable scheme can mix the emasculation agent with the safener/protective agent before the female parent plant is treated (namely the pesticide is compounded or mixed), so that the safener/protective agent can synergistically produce the detoxification protection effect on the emasculation agent, and the workload of field fractional treatment is reduced.
These treatments result in pollen male sterility in the males, but with less damage to pistils and nutrients, and these male sterile plants can receive pollen from another normal plant as a male parent for seed production and set to produce hybrid seed.
In this example, photosynthesis inhibiting herbicides that are preferably used include, but are not limited to, common photoss PSII system inhibitors such as atrazine, zinone, isoproturon, diuron, bromoxynil, and the like; the dosages of conventional herbicides used are described by referring to manufacturers. When the plant is used on a plant to be emasculated, a plant sensitivity test should be performed in advance to find out a safe dose which can cause yellowing of leaf parts of the plant to be sprayed but cannot be dried up and withered, and a lower dose which does not cause serious phytotoxicity is used as a proper safe dose.
In this example, the acetolactate/hydroxy acid synthase-inhibiting chemical androgens used are preferably tribenuron-methyl, amidosulfuron, chlorsulfuron, sulfosulfuron, flucarbazone, trifloxysulfuron, and the like. The optimum chemical emasculation dose range can be referred to (Liu Zhiquan, etc. 5 herbicides influence on ALS enzyme activity of rape and emasculation evaluation, chinese oil crop theory, 2016,38 (6): 742-749, jiuyu, amino acid synthesis inhibitor herbicides induce male sterility effect evaluation of rape, crop theory, 2014,40 (2): 264-272). For example, in the case of a normal growth rape with a plant height of about 30 to 60cm in the bud period, and a single plant spray receiving amount required for spraying wet leaves of 2 to 5ml, a suitable concentration (calculated by the active ingredients) of the emasculation agent used is given as a reference interval: 0.1 to 0.5mg/L of tribenuron-methyl, 0.1 to 0.5mg/L of amidosulfuron, 0.15 to 1.0mg/L of chlorsulfuron, 0.3 to 1.5mg/L of flucarbazone-methyl, 10 to 100mg/L of sulfosulfuron-methyl and 1 to 5mg/L of nicosulfuron. In the case of use in combination with the safener of the present invention, the dosage of the androgens may be suitably increased, for example by a factor of 0.2 to 1; the method of increasing the dosage may be to increase the concentration, or to increase the amount of the treatment solution, or to increase both the concentration and the amount of the treatment solution. The specific concentration is determined according to the average plant receiving amount of the plants and the plant nutrient body size in the treatment modes such as spraying.
The application of the herbicide for inhibiting photosynthesis as the safener and/or the safener of the acetolactate/hydroxy acid synthetase inhibitor chemical emasculator has the following positive effects:
the safener/protectant is a new concept proposed by the inventor according to the bottleneck of chemical emasculation technology development, and the implementation difficulty of the safener/protectant is much higher than that of herbicide safeners, and the stamens and other organs of the same crop are selectively protected; because of the lack of theoretical knowledge, the screening range is quite blind. According to the conventional principle of pesticide blending, the combined use of the herbicide and the acetolactate/hydroxy acid synthetase inhibitor such as sulfonylurea can aggravate phytotoxicity and weed control effect. The herbicide inhibiting photosynthesis designed in this example as safener and/or protectant for acetolactate/hydroxy acid synthase-inhibiting chemical androgens was not intentionally selected by those skilled in the art and therefore had unexpected technical effects. By implementing the given safener/protectant as a synergistic protection means, a stable emasculation effect can be obtained, the phytotoxicity is remarkably reduced compared with that of an emasculation agent without the synergistic safener/protectant, and the seed production yield is improved on the premise of ensuring the seed production purity. The application of the safener/protectant reduces the risk of seed production failure of seed production enterprises, and increases the economic benefits of seed production bearing farmers; by ensuring the purity and uniformity of the commercial hybrid seeds and the heterosis performance, the planting benefits of users who purchase the hybrid seeds are protected, so the method has great market application prospect.
The following are specific application examples given by the inventors, and it should be noted that the present invention is not limited to these examples. Application example 1: treatment effect of combination of tribenuron-methyl and different pesticides on rape
In 2021, the applicant's inventors have performed a comparison of the effect of benzenesulfon Long Jiazhi (TBM) androgens and various formulations thereof. The method is characterized in that a rape inbred line XD planted in a test farm of northwest agriculture and forestry university Cao Xinzhuang is used as a female parent, and spray treatment is carried out in a bud development period (3 late month) after bolting of spring rape. The control is benzenesulfon Long Jiazhi TBM treated alone (0.3 mg/L), and penetration enhancer (esterified vegetable oil or organosilicon) is added during dispensing and spraying to completely spray all leaves of the lettuce. Compounding treatment of tribenuron-methyl and growth regulating substances with the same concentration: TBM+gibberellin GA3 (0.02 g/L), TBM+brassinolide BR (0.1 mg/L), TBM+indolebutyric acid IBA (100 mg/L), TBM+paclobutrazol MET (0.25 g/L). The herbicide metribuzin MTB and isoproturon IPU are respectively mixed with TBM with the same concentration for treatment: TBM+MTB (0.35 g/L), TBM+IPU1 (0.5 g/L), TBM+IPU2 (1.5 g/L).
The treatment effect was investigated after 2-3 weeks. The TBM is found to have serious phytotoxicity, yellow new leaves, purple leaf edges, hardened stems and leaves, difficult bolting and flowering, and the formed flower buds are withered, yellow and shed. And the phytotoxicity is relieved until a large number of lateral branches and ineffective buds occur after one month.
Blending effect of TBM and growth regulating substance: tbm+ga3 aggravates phytotoxicity; TBM+BR and TBM+IBA treatments are basically ineffective, and do not contribute to the improvement of phytotoxicity; TBM+MET causes significant delay of bolting flowering for 9 days, so the method has a slight alleviating effect on phytotoxicity, but the phytotoxicity is still heavier.
In contrast (see table 1), both tbm+mtb and tbm+ipu were able to significantly reduce the phytotoxicity of TBM: the color of the young leaves of the two treated stems is normal compared with that of the young leaves of the TBM treated independently, and the damage of the TBM to chloroplasts is reduced by the IPU+TBM mixed treatment observed by an electron microscope (figures 1 and 2); the flowering time was essentially the same as that of normal rape or delayed by half a day, and organ damage was not apparent in terms of petal size (fig. 3), pollination seed setting rate of pistil, plant growth rate, etc. (table 1), while still maintaining high male sterility (fig. 3, 4, table 1). The mixed safener/protectant obviously relieves the toxic effect of chemical emasculation on non-stamen organs. The result shows that the adoption of the blending of the metribuzin MTB and the isoproturon IPU with the TBM is an effective means for solving the technical obstacle of safe use of the androgens.
Table 1: female and stamen fertility and plant development comparison of rape treated by compounding tribenuron-methyl (TBM) and pesticides
Application example 2: influence of separate spraying of tribenuron-methyl and isoproturon on rape
In spring 2021, the inventor of the applicant performs a fractional spraying test on rape, namely TBM solution (0.225 mg/L) and isoproturon (0.5 g/L) in the above example, and the treatment is separated at intervals of 1 hour, 1 day and 3 days; rape inbred XD was treated similarly with TBM and metribuzin (0.35 g/L) 1 hr, 1 day, 3 days apart. The result shows that the separate treatment has certain effect of alleviating the phytotoxicity, which indicates that the detoxification is not a physical and chemical reaction of the mixed medicines. However, the interval between the separate treatments should not be too long, the shorter the effect is (Table 2).
Table 2: influence of separate spraying of tribenuron-methyl and isoproturon on rape
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Application example 3: influence of combination of emasculation agent and isoproturon with different concentrations on rape
In 2022, the applicant's inventors performed a comparison of the effect of compounding various concentrations of tribenuron-methyl TBM with IPU. The method is characterized in that the rape self-bred line XD planted in autumn in a test field is used as a female parent, and spray treatment is carried out in a bud development period after bolting of the rape in spring. TBM alone at 0.15, 0.30, 0.45, 0.60mg/L TBM; the compounding treatment is to add isoproturon (0.5 g/L) based on separate treatment of TBM with different concentrations. Before spraying, adding penetration assisting agent (esterified vegetable oil or detergent) to wet the upper and lower leaves of rape.
The results show that the blending treatment of TBM and IPU with different concentrations has a certain detoxification effect, but the detoxification capacity of the IPU is only in a limited range of 2-3 times of TBM, and the TBM concentration is sharply reduced along with the increase of TBM concentration (see Table 3), so that the increase of TBM concentration during the blending of the TBM and the IPU is not more than 2 times.
Table 3: effect of treating rape with different concentrations of emasculation agent or isoproturon
Application example 4: influence of mixed treatment of different emasculation agents and PSII target herbicides on rape
In 2022, the inventors performed a comparison of the effects of the combination treatment of different androgens and PSII target herbicides. The rape Zhejiang oil 267 planted in autumn in a test field of a farm is used as a female parent, and spray treatment is carried out in a bud development period after bolting of the rape in spring. The test sets 1 blank control, the imidazolinone emamectin benzoate is 7.5mg/L, the sulfonylurea emamectin benzoate is 0.6mg/L, the amidosulfuron is 0.3mg/L and is singly treated and mixed with isoproturon (IPU 1 g/L), and the tribenuron-methyl (0.3 mg/L) and 3 PSII inhibiting herbicides of different families are mixed and treated, wherein the mixed and treated comprise TBM+bentazone (bentazone 1.0 g/L), TBM+bromoxynil (0.5 g/L) and TBM+atrazine (2 g/L). Before spraying, adding penetration assisting agent (esterified vegetable oil or detergent), and spraying wet whole plant leaves of rape.
The results show (see table 4): compared with 3 kinds of emasculation agents, namely imazethapyr, trifloxysulfuron and amidosulfuron which are treated independently, the emasculation effect of the emasculation agent after the hybrid treatment of the emasculation agent and isoproturon is similar, and the pollen activity level is similar; but the pollination seed setting rate of the plant growth and pistil is obviously improved. The detoxification effect of isoproturon is proved to have a certain detoxification effect on the treatment of three androgens with different structures. The tribenuron-methyl and 3 herbicides are mixed, and compared with the independent treatment of the tribenuron-methyl, the TBM+bentazone, TBM+bromoxynil and TBM+atrazine are male sterile, but the mixed treatment has a certain protection effect on plant growth and pollination seed setting of pistil.
Table 4: effect of treating rape with different emasculation agents or mixtures with herbicides
| Treatment of | Pollen vitality% | Pollination yield g of single plant | Plant height cm |
| Blank control | 94.28 | 15.7 | 146.6 |
| Micao cigarette | 2.63 | 13.9 | 148.3 |
| imazethapyr+IPU | 2.15 | 15.0 | 146.2 |
| Trifluazinsulfuron | 4.33 | 7.8 | 139.0 |
| Trifluazinsulfuron+IPU | 6.07 | 11.3 | 142.7 |
| Acrylsulfuron-methyl | 0.08 | 14.7 | 142.9 |
| Acrylsulfuron+IPU | 0.12 | 16.3 | 144.3 |
| TBM+bentazone | 0.04 | 15.5 | 146.2 |
| TBM+bromoxynil | 0.00 | 14.8 | 150.7 |
| TBM+atrazine | 0.01 | 14.2 | 142.5 |
| TBM | 0.04 | 13.4 | 138.3 |
Application example 5: influence of the Mixed treatment of the emasculation agent TBM and isoproturon on cabbage and mustard
In 2022, the inventors performed a comparison of the emasculation effect of the combination of the emasculation agent TBM and isoproturon on cabbage and mustard. The method is characterized in that the autumn sowing planting of the cabbages Qin Bai, the Shanghai green of the cabbages and the Qiangshanhuang of the leaf mustard in the test field of the farm is used as targets, and the spray treatment is carried out in the bud development period after bolting in spring. 1 control is set for the test, and tribenuron-methyl is treated independently at a concentration of 0.3 mg/L; compounding treatment of 0.3mg/L TBM+IPU isoproturon (0.5 g/L). Before spraying, adding penetration assisting agent (esterified vegetable oil or detergent), and spraying wet whole plant leaves of rape.
The results indicated (see table 5): compared with the independent treatment of the androstat TBM, the mixed treatment of the androstat TBM and isoproturon has similar androstatic effect and similar pollen abortion rate. But the pollination seed setting rate of the cabbage plants, the mustard plants and the pistils is obviously improved. The method shows that the mixed treatment of isoproturon and the androgens tribenuron-methyl has a certain detoxification effect on three different plants.
Table 5: effect of treating cabbage and mustard by mixing androgenic TBM and isoproturon
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Claims (6)
1. Use of a photosynthesis inhibiting herbicide as safener for acetolactate/hydroxy acid synthase inhibiting chemical androgens; the application is characterized by being implemented according to the following method: after acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent and photosynthesis inhibiting herbicide are mixed, spraying female parent of target plant;
the target plant is rape;
the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is tribenuron-methyl, and the photosynthesis inhibiting herbicide is metribuzin and isoproturon;
the concentrations of the tribenuron-methyl and the metribuzin are respectively 0.3 mg/L and 0.35 g/L; or the concentrations of the tribenuron-methyl and the isoproturon are respectively 0.3 mg/L and 0.5 g/L; or the concentrations of the tribenuron-methyl and the isoproturon are respectively 0.3 mg/L and 1.5 g/L.
2. Use of a photosynthesis inhibiting herbicide as safener for acetolactate/hydroxy acid synthase inhibiting chemical androgens; the application is characterized by being implemented according to the following method: after acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent and photosynthesis inhibiting herbicide are mixed, spraying female parent of target plant; or spraying the female parent of the target plant with acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent and photosynthesis inhibiting herbicide within 72 hr;
the target plant is rape;
the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is tribenuron-methyl, and the photosynthesis inhibiting herbicide is metribuzin and isoproturon;
the concentrations of the tribenuron-methyl and the metribuzin are respectively 0.225 mg/L and 0.35 g/L; the concentrations of the tribenuron-methyl and the isoproturon are respectively 0.225 mg/L and 0.5 g/L.
3. Use of a photosynthesis inhibiting herbicide as safener for acetolactate/hydroxy acid synthase inhibiting chemical androgens; the application is characterized by being implemented according to the following method: after acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent and photosynthesis inhibiting herbicide are mixed, spraying female parent of target plant;
The target plant is rape;
the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is tribenuron-methyl, and the photosynthesis inhibiting herbicide is isoproturon;
the concentrations of the tribenuron-methyl and the isoproturon are respectively 0.15 mg/L and 0.5 g/L.
4. Use of a photosynthesis inhibiting herbicide as safener for acetolactate/hydroxy acid synthase inhibiting chemical androgens; the application is characterized by being implemented according to the following method: after acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent and photosynthesis inhibiting herbicide are mixed, spraying female parent of target plant;
the target plant is rape;
the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is imazethapyr, and the photosynthesis inhibiting herbicide is isoproturon; the concentration of the imazethapyr and the isoproturon are 7.5 mg/L and 1 g/L respectively;
or the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is trifloxysulfuron, and the herbicide for inhibiting photosynthesis is isoproturon; the concentrations of the trifloxysulfuron and the isoproturon are respectively 0.6 mg/L and 1 g/L;
or the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is amidosulfuron, and the herbicide for inhibiting photosynthesis is isoproturon; the concentrations of the amidosulfuron and isoproturon are respectively 0.3 mg/L and 1 g/L.
5. Use of a photosynthesis inhibiting herbicide as safener for acetolactate/hydroxy acid synthase inhibiting chemical androgens; the application is characterized by being implemented according to the following method: after acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent and photosynthesis inhibiting herbicide are mixed, spraying female parent of target plant;
the target plant is rape;
the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is tribenuron-methyl, and the herbicide for inhibiting photosynthesis is bentazone; the concentrations of the tribenuron-methyl and bentazone are respectively 0.3 mg/L and 1 g/L;
or the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is tribenuron methyl, and the herbicide for inhibiting photosynthesis is bromoxynil; the concentrations of the tribenuron-methyl and bromoxynil are respectively 0.3 mg/L and 0.5 g/L;
or the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is tribenuron methyl, and the herbicide for inhibiting photosynthesis is atrazine; the concentrations of the tribenuron-methyl and atrazine are respectively 0.3 mg/L and 2 g/L.
6. Use of a photosynthesis inhibiting herbicide as safener for acetolactate/hydroxy acid synthase inhibiting chemical androgens; the application is characterized by being implemented according to the following method: after acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent and photosynthesis inhibiting herbicide are mixed, spraying female parent of target plant;
The target plants are Chinese cabbage Qin Bai, chinese cabbage Shanghai Qing and mustard Qiang mountain Huang;
the acetolactate/hydroxy acid synthetase inhibiting chemical emasculation agent is tribenuron-methyl, and the photosynthesis inhibiting herbicide is isoproturon; the concentrations of the tribenuron-methyl and the isoproturon are respectively 0.3 mg/L and 0.5 g/L.
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