CN116249457A - 气溶胶形成基质 - Google Patents
气溶胶形成基质 Download PDFInfo
- Publication number
- CN116249457A CN116249457A CN202180067167.8A CN202180067167A CN116249457A CN 116249457 A CN116249457 A CN 116249457A CN 202180067167 A CN202180067167 A CN 202180067167A CN 116249457 A CN116249457 A CN 116249457A
- Authority
- CN
- China
- Prior art keywords
- aerosol
- forming substrate
- content
- weight
- cellulose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000443 aerosol Substances 0.000 title abstract description 70
- 239000011159 matrix material Substances 0.000 title description 2
- 239000000758 substrate Substances 0.000 claims abstract description 604
- 229920002678 cellulose Polymers 0.000 claims abstract description 90
- 239000001913 cellulose Substances 0.000 claims abstract description 90
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims abstract description 79
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims abstract description 79
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims abstract description 79
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims abstract description 79
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 53
- 239000012744 reinforcing agent Substances 0.000 claims abstract description 20
- 235000010980 cellulose Nutrition 0.000 claims description 88
- 239000003623 enhancer Substances 0.000 claims description 58
- 229920003043 Cellulose fiber Polymers 0.000 claims description 54
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 51
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 51
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 51
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 51
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 50
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 40
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 40
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 40
- 230000002787 reinforcement Effects 0.000 claims description 11
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 10
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 10
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 10
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 50
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 46
- 229960002715 nicotine Drugs 0.000 description 46
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 39
- 238000010438 heat treatment Methods 0.000 description 33
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 27
- 230000006698 induction Effects 0.000 description 16
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 12
- 235000011187 glycerol Nutrition 0.000 description 12
- 238000004519 manufacturing process Methods 0.000 description 11
- 239000000203 mixture Substances 0.000 description 11
- 230000000052 comparative effect Effects 0.000 description 10
- 238000009472 formulation Methods 0.000 description 10
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 10
- 229920001817 Agar Polymers 0.000 description 9
- 239000008272 agar Substances 0.000 description 9
- 239000002002 slurry Substances 0.000 description 7
- JOOXCMJARBKPKM-UHFFFAOYSA-N 4-oxopentanoic acid Chemical compound CC(=O)CCC(O)=O JOOXCMJARBKPKM-UHFFFAOYSA-N 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 6
- 150000001735 carboxylic acids Chemical class 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 6
- 235000019504 cigarettes Nutrition 0.000 description 6
- 238000012546 transfer Methods 0.000 description 6
- 229920002301 cellulose acetate Polymers 0.000 description 5
- 235000014655 lactic acid Nutrition 0.000 description 5
- 239000004310 lactic acid Substances 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 4
- 238000002788 crimping Methods 0.000 description 4
- 239000006199 nebulizer Substances 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 125000006850 spacer group Chemical group 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 229940040102 levulinic acid Drugs 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000007423 decrease Effects 0.000 description 2
- 230000005672 electromagnetic field Effects 0.000 description 2
- 230000005415 magnetization Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000000391 smoking effect Effects 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- AIBWPBUAKCMKNS-PPHPATTJSA-N 2-hydroxybenzoic acid;3-[(2s)-1-methylpyrrolidin-2-yl]pyridine Chemical compound OC(=O)C1=CC=CC=C1O.CN1CCC[C@H]1C1=CC=CN=C1 AIBWPBUAKCMKNS-PPHPATTJSA-N 0.000 description 1
- SDVKWBNZJFWIMO-UHFFFAOYSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;3-(1-methylpyrrolidin-2-yl)pyridine Chemical compound CN1CCCC1C1=CC=CN=C1.OC(=O)CC(O)(C(O)=O)CC(O)=O SDVKWBNZJFWIMO-UHFFFAOYSA-N 0.000 description 1
- VWTHFJXLFGINSW-PPHPATTJSA-N 2-hydroxypropanoic acid;3-[(2s)-1-methylpyrrolidin-2-yl]pyridine Chemical compound CC(O)C(O)=O.CN1CCC[C@H]1C1=CC=CN=C1 VWTHFJXLFGINSW-PPHPATTJSA-N 0.000 description 1
- MMOPGICOOYBFJU-UHFFFAOYSA-N 3-(1-methylpyrrolidin-2-yl)pyridine;2-oxopropanoic acid Chemical compound CC(=O)C(O)=O.CN1CCCC1C1=CC=CN=C1 MMOPGICOOYBFJU-UHFFFAOYSA-N 0.000 description 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 1
- 102100033864 G-protein coupled receptor 84 Human genes 0.000 description 1
- 101001069589 Homo sapiens G-protein coupled receptor 84 Proteins 0.000 description 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
- 241000208125 Nicotiana Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 229920002230 Pectic acid Polymers 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 229940072056 alginate Drugs 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- AEMOLEFTQBMNLQ-BKBMJHBISA-N alpha-D-galacturonic acid Chemical compound O[C@H]1O[C@H](C(O)=O)[C@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-BKBMJHBISA-N 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- VAUQRLHPXWYZRZ-PPHPATTJSA-N benzoic acid 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine Chemical compound OC(=O)c1ccccc1.CN1CCC[C@H]1c1cccnc1 VAUQRLHPXWYZRZ-PPHPATTJSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 238000002485 combustion reaction Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- LDMPZNTVIGIREC-ZGPNLCEMSA-N nicotine bitartrate Chemical compound O.O.OC(=O)[C@H](O)[C@@H](O)C(O)=O.OC(=O)[C@H](O)[C@@H](O)C(O)=O.CN1CCC[C@H]1C1=CC=CN=C1 LDMPZNTVIGIREC-ZGPNLCEMSA-N 0.000 description 1
- 229940069688 nicotine bitartrate Drugs 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/36—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring
- A24B15/40—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms
- A24B15/403—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms having only oxygen as hetero atoms
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D1/00—Cigars; Cigarettes
- A24D1/20—Cigarettes specially adapted for simulated smoking devices
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Manufacture Of Tobacco Products (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20200643 | 2020-10-07 | ||
| EP20200643.3 | 2020-10-07 | ||
| PCT/EP2021/077782 WO2022074157A1 (en) | 2020-10-07 | 2021-10-07 | An aerosol-forming substrate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116249457A true CN116249457A (zh) | 2023-06-09 |
Family
ID=72801431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180067167.8A Pending CN116249457A (zh) | 2020-10-07 | 2021-10-07 | 气溶胶形成基质 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230404132A1 (es) |
| EP (1) | EP4225055A1 (es) |
| JP (1) | JP2023544038A (es) |
| KR (1) | KR20230080444A (es) |
| CN (1) | CN116249457A (es) |
| AU (1) | AU2021357355A1 (es) |
| BR (1) | BR112023006128A2 (es) |
| CA (1) | CA3195031A1 (es) |
| IL (1) | IL301819A (es) |
| MX (1) | MX2023003823A (es) |
| WO (1) | WO2022074157A1 (es) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4333484A (en) * | 1978-08-02 | 1982-06-08 | Philip Morris Incorporated | Modified cellulosic smoking material and method for its preparation |
| US5613505A (en) | 1992-09-11 | 1997-03-25 | Philip Morris Incorporated | Inductive heating systems for smoking articles |
| WO2004087089A2 (en) * | 2003-03-26 | 2004-10-14 | The Procter & Gamble Company | Rapidly dissolving edible film compositions with improved film strength and stability |
| JP4931596B2 (ja) * | 2003-11-07 | 2012-05-16 | ユーエス スモークレス タバコ カンパニー リミテッド ライアビリティ カンパニー | タバコ組成物 |
| TWI692274B (zh) | 2014-05-21 | 2020-04-21 | 瑞士商菲利浦莫里斯製品股份有限公司 | 用於加熱氣溶膠形成基材之感應加熱裝置及操作感應加熱系統之方法 |
| US11324249B2 (en) * | 2019-03-06 | 2022-05-10 | R.J. Reynolds Tobacco Company | Aerosol delivery device with nanocellulose substrate |
| EP4110093A1 (en) | 2020-02-28 | 2023-01-04 | Philip Morris Products S.A. | Novel aerosol-generating substrate |
-
2021
- 2021-10-07 MX MX2023003823A patent/MX2023003823A/es unknown
- 2021-10-07 JP JP2023520182A patent/JP2023544038A/ja active Pending
- 2021-10-07 AU AU2021357355A patent/AU2021357355A1/en active Pending
- 2021-10-07 EP EP21782770.8A patent/EP4225055A1/en active Pending
- 2021-10-07 WO PCT/EP2021/077782 patent/WO2022074157A1/en unknown
- 2021-10-07 IL IL301819A patent/IL301819A/en unknown
- 2021-10-07 KR KR1020237014419A patent/KR20230080444A/ko unknown
- 2021-10-07 US US18/247,294 patent/US20230404132A1/en active Pending
- 2021-10-07 CN CN202180067167.8A patent/CN116249457A/zh active Pending
- 2021-10-07 CA CA3195031A patent/CA3195031A1/en active Pending
- 2021-10-07 BR BR112023006128A patent/BR112023006128A2/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112023006128A2 (pt) | 2023-05-09 |
| IL301819A (en) | 2023-06-01 |
| MX2023003823A (es) | 2023-04-13 |
| US20230404132A1 (en) | 2023-12-21 |
| AU2021357355A9 (en) | 2024-05-02 |
| WO2022074157A1 (en) | 2022-04-14 |
| AU2021357355A1 (en) | 2023-05-04 |
| EP4225055A1 (en) | 2023-08-16 |
| JP2023544038A (ja) | 2023-10-19 |
| CA3195031A1 (en) | 2022-04-14 |
| KR20230080444A (ko) | 2023-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |