CN116236679A

CN116236679A - Tissue glue applying device

Info

Publication number: CN116236679A
Application number: CN202111495617.1A
Authority: CN
Inventors: 陈慧军; 魏鹏飞; 王华生; 李学军; 赵博
Original assignee: BEIJING BIOSIS HEALING BIOLOGICAL TECHNOLOGY CO LTD
Current assignee: BEIJING BIOSIS HEALING BIOLOGICAL TECHNOLOGY CO LTD
Priority date: 2021-12-08
Filing date: 2021-12-08
Publication date: 2023-06-09

Abstract

A tissue gel application device, the tissue gel application device comprising: a first syringe configured to hold a first liquid; a second syringe configured to hold a second liquid; and a mixing device comprising a first branch and a second branch in communication with the first and second syringes, respectively, each of the first and second branches being provided with a channel switching assembly comprising: a storage member having a receiving portion; a tap rotatably provided in the housing, the tap being internally provided with a first passage and a second passage which do not interfere with each other, the tap being switchable relative to the housing between a first position and a second position, in response to the tap being switched to the first position, a syringe corresponding to the branch being in communication with the first passage, and in response to the tap being switched to the second position, a syringe corresponding to the branch being in communication with the second passage.

Description

Tissue glue applying device

Technical Field

The disclosure relates to the technical field of medicines, and in particular relates to a tissue gel applying device.

Background

The tissue adhesive is used for binding human tissues, and can be directly coated or sprayed on wounds or wound surfaces for wound healing. Medical hydrogel, which is a kind of tissue gel, is a novel functional polymer material with hydrophilic groups, and is a polymer which can be swelled by water but is insoluble in water and has a three-dimensional network structure. The modified cellulose has the characteristics of biological safety, modifier, good mechanical property and the like, and has wide application in the fields of biological medicine, agriculture, industry, environmental protection and the like. In the biomedical field, the hydrogel can be used as a medical dressing to cover a wound so as to realize rapid healing. In addition, the hydrogel can also be used as a drug slow release carrier, a tissue engineering material, an oral cavity application material and the like, and has a very wide application prospect in the biomedical field due to the porous and soft properties, high water content and high tissue compatibility. Currently, a variety of hydrogel materials are commercially available for clinical hemostatic sealing.

The medical hydrogel has a very wide application range, and can be applied to various wound surfaces including body surfaces, bodies and the like. In the prior art, hydrogel is mainly applied by double syringes, but the application of the hydrogel to a wound in vivo, especially the wound gluing in endoscopic surgery, is realized.

Disclosure of Invention

Some embodiments of the present disclosure provide a tissue gel application device comprising:

a first syringe configured to hold a first liquid;

a second syringe configured to hold a second liquid; and

a mixing device comprising a first branch and a second branch which are respectively communicated with the first injector and the second injector,

each of the first and second legs is provided with a channel switching assembly,

the channel switching assembly includes:

a storage member having a receiving portion;

a cock rotatably provided in the housing, the cock having a first passage and a second passage which do not interfere with each other,

the tap is switchable relative to the housing between a first position and a second position, the syringe corresponding to the branch being in communication with the first passageway in response to the tap being switched to the first position, and the syringe corresponding to the branch being in communication with the second passageway in response to the tap being switched to the second position.

In some embodiments, the mixing device further comprises: a mixing pipe which is communicated with the first branch and the second branch,

the side wall of the accommodating part is provided with a first through hole and a second through hole, the first through hole is communicated with the corresponding injector of the branch through a first sub-part of the branch, and the second through hole is communicated with the mixing pipe fitting through a second sub-part of the branch.

In some embodiments, the faucet comprises:

the cock body is accommodated in the accommodating part;

a needling part extending from one end of the cock body along the axis direction of the cock body away from the cock body,

at least a portion of the needling section is located outside of the receptacle, the needling section being configured to pierce a container containing powder,

the first passage extends from the rotating body into the needling portion and includes a first opening on a sidewall of the needling portion, the first opening being located outside the receiving portion.

In some embodiments, the first passageway further comprises a second opening on a sidewall of the tap body, the second opening interfacing with the first through bore in response to the tap being switched to the first position.

In some embodiments, the needling portion further includes a first identifier extending from the needling portion sidewall in the axial direction of the second opening.

In some embodiments, the second passageway extends within the tap body and includes a third opening and a fourth opening on a sidewall of the tap body that interface with the first and second through holes, respectively, in response to the tap being switched to the second position.

In some embodiments, the needling portion further includes a second identifier extending from the needling portion sidewall in the axial direction of the third opening and a third identifier extending from the needling portion sidewall in the axial direction of the fourth opening.

In some embodiments, the third opening is disposed opposite the fourth opening and both are symmetrical with respect to the axis of the tap body.

In some embodiments, the tap is switchable to a third position relative to the receptacle such that the syringe corresponding to the branch is disconnected from both the first passageway and the second passageway.

In some embodiments, the tissue gel application device further comprises:

the clamp comprises a first clamping groove and a second clamping groove which are oppositely arranged,

the first and second syringes each include a sleeve and a pushrod slidably received within the sleeve,

the sleeves of the first syringe and the second syringe are respectively clamped in the first clamping groove and the second clamping groove, so that the first syringe and the second syringe are arranged in parallel.

In some embodiments, the tissue gel application device further comprises a pusher clip connected to the ends of the pushers of the first and second syringes distal from the cannula such that the pushers of the first and second syringes move in synchrony.

In some embodiments, the pusher grip further comprises an annular grip disposed on a side of the pusher grip remote from the pusher.

In some embodiments, the mixing device further comprises an outlet, and the tissue gel application device comprises a spray head disposed at the outlet of the mixing device.

Compared with the related art, the method has at least the following technical effects:

the tissue adhesive applying device adopts a double-injector to contain two pipes of liquid, and correspondingly adopts a plurality of penicillin bottles and other containers to store different types of solutes, and all the raw materials are mutually separated, so that the preservation of the materials forming the tissue adhesive is facilitated. The channel switching assembly of the tissue gel application device is in different states, the process of mixing the liquid with the liquid is distinguished from the process of mixing the liquid in the double syringe with the hydrogel, and the tissue gel is further directly applied. The tissue gel is formed and utilized, so that the advantages of full reaction of liquid-level mutual mixing and rapid application are realized.

Drawings

In order to more clearly illustrate the embodiments of the present disclosure or the technical solutions in the prior art, a brief description will be given below of the drawings required for the embodiments or the description of the prior art, and it is obvious that the drawings in the following description are some embodiments of the present disclosure, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic illustration of a tissue gel applicator provided in some embodiments of the present disclosure;

FIG. 2 is a schematic diagram of a syringe of a tissue gel application device provided in some embodiments of the present disclosure;

FIG. 3 is a schematic perspective view of a syringe of a tissue gel application device provided in some embodiments of the present disclosure;

FIG. 4 is a schematic structural view of a mixing device of a tissue gel application device provided in some embodiments of the present disclosure;

fig. 5 is a schematic structural diagram of a channel switching component provided in some embodiments of the present disclosure;

fig. 6 is a schematic structural view of a receiving member provided in some embodiments of the present disclosure;

FIG. 7 is a perspective view of a structure of a receiving member provided by some embodiments of the present disclosure;

FIG. 8 is a schematic view of a cock provided in some embodiments of the present disclosure;

FIG. 9 is a perspective view of a faucet provided in some embodiments of the present disclosure

FIG. 10 is a schematic structural view of a clamp of a tissue glue application device provided in some embodiments of the present disclosure; and

fig. 11 is a schematic structural view of a push rod clip of a tissue glue application device provided in some embodiments of the present disclosure.

Detailed Description

For the purpose of promoting an understanding of the principles and advantages of the disclosure, reference will now be made in detail to the drawings, in which it is apparent that the embodiments described are only some, but not all embodiments of the disclosure. Based on the embodiments in this disclosure, all other embodiments that a person of ordinary skill in the art would obtain without making any inventive effort are within the scope of protection of this disclosure.

The terminology used in the embodiments of the disclosure is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. As used in this disclosure of embodiments and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise, the "plurality" generally includes at least two.

It should be understood that the term "and/or" as used herein is merely one relationship describing the association of the associated objects, meaning that there may be three relationships, e.g., a and/or B, may represent: a exists alone, A and B exist together, and B exists alone. In addition, the character "/" herein generally indicates that the front and rear associated objects are an "or" relationship.

It should also be noted that the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a product or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such product or apparatus. Without further limitation, an element defined by the phrase "comprising" does not exclude the presence of other like elements in a commodity or device comprising such element.

In the art, after mixing various components such as solid, liquid and the like, tissue gel, for example, medical hydrogel, is required to be mixed in liquid level to achieve the effects of complete gel formation and uniform gel formation in order to fully react the components. The adoption of such a fully mixed reaction mode results in a relatively high reaction speed, and the hydrogel needs to be applied to the tissue to be treated in time, so that a relatively high requirement is placed on the applicator. Thus, manipulation with tissue glue, such as coating a wound, requires a means of immediate creation and use. The tissue gel, such as a medical hydrogel, in the present disclosure may be formed by mixing two solutions, i.e., a first solution and a second solution, which are not well stable nor can be stored for a long period of time. The first solution may be generated by reacting a first solute with a first liquid, and the second solution may be generated by reacting a second solute with a second liquid. The first solute, the first liquid, the second solute, and the second liquid are all readily storable substances. In order to perform medical treatment using the tissue glue of the present disclosure, it is necessary to generate a first solution using a first solute and a first liquid, generate a second solution using a second solute and a second liquid, and react the first solution and the second solution to generate the tissue glue. For this reason, there is a relatively high demand for the structure of the tissue glue application device so that it can store at least one of the first solute, the first liquid, the second solute, and the second liquid for a long period of time, and can simply and rapidly generate and apply the tissue glue when performing the operation.

The present disclosure provides a tissue gel application device comprising: a first syringe configured to hold a first liquid; a second syringe configured to hold a second liquid; and a mixing device comprising a first branch and a second branch in communication with the first and second syringes, respectively, each of the first and second branches being provided with a channel switching assembly comprising: a storage member having a receiving portion; a tap rotatably disposed in the housing, the rotation being provided internally with a first passage and a second passage which do not interfere with each other, the tap being switchable relative to the housing between a first position and a second position, in response to the tap being switched to the first position, a syringe corresponding to the branch being in communication with the first passage, and in response to the tap being switched to the second position, a syringe corresponding to the branch being in communication with the second passage.

The tissue adhesive applying device is adopted, the double syringes are used for accommodating two specific liquids, and a plurality of penicillin bottles and other containers are correspondingly adopted for storing a plurality of solutes, so that the preservation of materials forming the tissue adhesive is facilitated. The channel switching assembly of the tissue glue applying device is in different states, specific liquid and specific solute are respectively mixed to form specific solutions of the two, and the two solutions are mixed to form the tissue glue and are directly applied. The tissue gel is formed and utilized immediately, so that the reactant is fully mixed, the gel forming reaction is uniform and rapid, and the wound surface is effectively protected.

Alternative embodiments of the present disclosure are described in detail below with reference to the drawings.

Fig. 1 is a schematic structural view of a tissue gel applying device provided in some embodiments of the present disclosure.

As shown in fig. 1, the tissue gel application device 100 includes a dual syringe and a mixing device 30. The dual syringes are, for example, a first syringe 10 and a second syringe 20. The first syringe 10 and the second syringe 20 have the same structure. The first syringe 10 is for example configured to hold a first liquid and the second syringe 20 is for example configured to hold a second liquid. That is, the first liquid and the second liquid for generating the tissue gel may be stored in the first syringe 10 and the second syringe 20 of the tissue gel application device 100, respectively.

Fig. 2 is a schematic structural view of an injector of the tissue gel applying device according to some embodiments of the present disclosure, and fig. 3 is a schematic structural perspective view of an injector of the tissue gel applying device according to some embodiments of the present disclosure, and the first injector 10 is illustrated herein as an example because the structures of the first injector 10 and the second injector 20 are identical. As shown in fig. 2 and 3, the first syringe 10 comprises a cannula 11 and a push rod 12 slidably received in said cannula 11, the push rod 12 being provided with a piston 13 near the outlet of the cannula 11, i.e. at one end of the injection port of the syringe, the push rod 12 being movable in the cannula 11 by pushing and pulling the piston 13 for expelling liquid from the cannula 11 or for drawing liquid into the cannula 11.

Fig. 4 is a schematic structural view of a mixing device of a tissue gel application device according to some embodiments of the present disclosure. As shown in connection with fig. 1-4, the mixing device 30 comprises a first branch 31 and a second branch 32 and a mixing tube 33, the first branch 31 and the second branch 32 being in communication with the first syringe 10 and the second syringe 20, respectively, and both being in communication with the mixing tube 33. Specifically, both ends of the first branch 31 are respectively communicated with the first syringe 10 and the mixing tube 33, and both ends of the second branch 32 are respectively communicated with the second syringe 20 and the mixing tube 33. And each of the first leg 31 and the second leg 32 is provided with a channel switching assembly 34. The first branch 31 and the second branch 32 can control the connection or disconnection of their corresponding syringes 10 with the mixing tube 33 by a channel switching assembly 34 provided thereon. The channel switching assemblies 34 in the first leg 31 and the second leg 32 are substantially identical in structure, and the channel switching assembly 34 in the first leg 31 is explained below as an example.

Fig. 5 is a schematic structural view of a channel switching assembly provided by some embodiments of the present disclosure, fig. 6 is a schematic structural view of a receiving member provided by some embodiments of the present disclosure, fig. 7 is a perspective structural view of a receiving member provided by some embodiments of the present disclosure, fig. 8 is a schematic structural view of a tap provided by some embodiments of the present disclosure, and fig. 9 is a perspective structural view of a tap provided by some embodiments of the present disclosure. As shown in connection with fig. 1-9, the channel switch assembly 34 includes a receiving member 341 and a tap 342.

The receiving member 341 has a receiving portion 3411, and the receiving portion 3411 may be a cylindrical recess or a through hole. The side wall of the accommodating portion 3411 is provided with a first through hole 34111 and a second through hole 34112, the first through hole 34111 is communicated with a syringe (for example, the first syringe 10) corresponding to the branch (for example, the first branch 31) through a first sub-portion of the branch, and the second through hole 34112 is communicated with the mixing tube 33 through a second sub-portion of the branch (for example, the first branch 31).

The tap 342 is rotatably disposed in the receiving portion 3411, and the tap 342 is internally provided with a first passage 3421 and a second passage 3422 which do not interfere with each other. The tap 342 includes a tap body 3423 and a lancing portion 3424. Tap body 3423 is housed in housing 3411, and is rotatable with respect to housing 341 in housing 3411. The needle-punched portion 3424 extends from one end of the tap body 3423 away from the tap body 3423 in the tap body axial direction. At least a portion of the needled portion 3424 is located outside of the receptacle 3411, and is configured to pierce a container containing a powder, such as a penicillin bottle, that contains a solute for forming a tissue gel.

The first passageway 3421 extends from the rotating body 3423 into the needling portion 3424, which includes a first opening 34211 on a sidewall of the needling portion 3424, the first opening 34211 being located outside of the receiving portion 3411. The number of the first openings 34211 may be 1, and may be 2 or more, and when the number thereof is plural, they may be uniformly disposed circumferentially around the axis of the tap 342 on the side wall of the needling portion 3424. The first passageway 3421 further includes a second opening 34212, the second opening 34212 being located on a side wall of the tap body 3423.

The second passageway 3422 extends within the tap body 342, with the second passageway 3422 including a third opening 34221 and a fourth opening 34222 on the tap body side wall.

As shown in fig. 1-9, the tap 342 is switchable between a first position and a second position relative to the receptacle 3411, and when the tap 342 is switched to the first position, a syringe (e.g., the first syringe 10) corresponding to the branch (e.g., the first branch 31) communicates with the first passageway 3421. The second opening 34212 of the first passageway 3421 is now in abutting engagement with the first through-hole 34111, e.g., in sealing engagement. In this case, if the needle part 3424 of the tap 342 pierces the xiLin bottle containing the solute (e.g., the first solute) for forming the tissue cement, the syringe (e.g., the first syringe 10) may communicate with the xiLin bottle through the first passage 3421, whereby the liquid (e.g., the first liquid) of the syringe (e.g., the first syringe 10) may be injected into the xiLin bottle to be mixed with the solute (e.g., the first solute) in the xiLin bottle to form the first solution, and the first solution may be drawn into the syringe (e.g., the first syringe 10) by pulling the push rod of the syringe (e.g., the first syringe 10).

Similarly, the second syringe 20 may be filled with a second liquid held therein in the same manner into a vial containing a second solute for forming a tissue gel, and after forming a second solution, the second solution is drawn into the second syringe 20.

When the tap 342 is switched to the second position, a syringe (e.g., the first syringe 10) corresponding to the branch (e.g., the first branch 31) communicates with the second passage 3422. At this time, the third opening 34221 of the second passage 3422 is butted with the first through hole 34111, for example, sealed, and the fourth opening 34222 of the second passage 3422 is butted with the second through hole 34112, for example, sealed. I.e. the branch (e.g. the first branch 31) forms a passage through which the corresponding syringe (e.g. the first syringe 10) of the branch (e.g. the first branch 31) communicates with the mixing tube 33.

In this case, pushing the push rod 12 of the syringe (for example, the first syringe 10) may inject the first solution in the syringe (for example, the first syringe 10) into the mixing tube 33 through the branch (for example, the first branch 31). Similarly, the second syringe 20 may inject the second solution therein into the mixing tube 33 in the same manner. The first solution and the second solution are mixed and reacted in the mixing tube 33 to generate the tissue glue. Tissue cement may be output via the outlet of the mixing tube 33 for medical procedures.

With the tissue gel application device of the above embodiment, the first liquid and the second liquid are respectively stored in two syringes of the tissue gel application device, and the first solute and the second solute are respectively stored in separate containers, such as a penicillin bottle. When the tissue adhesive preparation device is used, the syringes can be communicated with the corresponding penicillin bottles through the channel switching assembly, the first liquid and the second liquid are respectively mixed with the first solute and the second solute to form the first solution and the second solution, the first solution and the second solution are respectively pumped into the corresponding syringes, the two syringes are communicated with the mixing pipe fitting through the channel switching assembly, the first solution and the second solution are pressed into the mixing pipe fitting to be mixed to form tissue adhesive, the tissue adhesive can be formed and utilized immediately, and the defects of short tissue adhesive storage time and easy deterioration are overcome.

In some embodiments, the tap 342 further includes a first marking member 3425, the first marking member 3425 extending from the sidewall of the needling portion 3424 along the axial direction of the second opening 34212 for marking the position of the second opening 34212. When the first identifier 3425 is directed to a corresponding syringe (e.g., the first syringe 10) and is substantially parallel to a corresponding leg (e.g., the first leg 31), it indicates that the second opening 34212 interfaces with the first through-hole 34111 and the syringe (e.g., the first syringe 10) communicates with the first passageway 3421.

In some embodiments, the tap 342 further comprises a second indicator 3426 extending from the lancing side wall in the axial direction of the third opening 34221 and a third indicator 3427 extending from the lancing side wall in the axial direction of the fourth opening 34222. The second and

third identifiers

3426 and 3427 are used to indicate the positions of the third and

fourth openings

34221 and 34222, respectively. When the second identifier 3426 is directed to the corresponding syringe (e.g., the first syringe 10) and is substantially parallel to the corresponding branch (e.g., the first branch 31), the third identifier 3427 is directed to the mixing tube 33 and is substantially parallel to the corresponding branch (e.g., the first branch 31), which indicates that the third opening 34221 of the second passageway 3422 is docked with the first through hole 34111, the fourth opening 34222 of the second passageway 3422 is docked with the second through hole 34112, and the syringe (e.g., the first syringe 10) is in communication with the second passageway 3422.

In some embodiments, the third opening 34221 of the second passageway 3422 is disposed opposite the fourth opening 34222, and both are disposed symmetrically with respect to the axis of the tap body 3423, and the first through hole 34111 and the second through hole 34112 on the side wall of the receiving portion 3411 are also disposed opposite, and both are also disposed symmetrically with respect to the axis of the tap body 3423. In this case, the third opening 34221 of the second passage 3422 may be butted with the second through hole 34112, and the fourth opening 34222 of the second passage 3422 is butted with the first through hole 34112, at which time the syringe (for example, the first syringe 10) is also communicated with the second passage 3422.

In some embodiments, the tap 342 is switchable to a third position relative to the housing 3411, that is, the tap 342 is switchable between a first position, a second position, and a third position relative to the housing 3411. When the cock 342 is switched to the third position, the syringe (for example, the first syringe 10) corresponding to the branch (for example, the first branch 31) is disconnected from both the first passage 3421 and the second passage 3422, and in this case, the outlet of the syringe (for example, the first syringe 10) is blocked, so that leakage of the liquid in the syringe (for example, the first syringe 10) is prevented.

Fig. 10 is a schematic structural view of a fixture of a tissue gel applying device according to some embodiments of the present disclosure, and in some embodiments, as shown in fig. 1 to 10, the tissue gel applying device 100 further includes a fixture 50, where the fixture 50 includes a first clamping groove 51 and a second clamping groove 52 that are disposed opposite to each other. The sleeves of the first syringe 10 and the second syringe 20 are respectively clamped in the first clamping groove 51 and the second clamping groove 52, so that the first syringe 10 and the second syringe 20 are arranged in parallel. Facilitating the synchronous operation of the two syringes.

Fig. 11 is a schematic structural view of a push rod clip of a tissue gel application device according to some embodiments of the present disclosure, and in some embodiments, as shown in fig. 1-11, the tissue gel application device 100 further includes a push rod clip 40, where the push rod clip 40 is connected to ends of push rods of the first syringe 10 and the second syringe 20 away from the cannula, so that the push rods of the first syringe 10 and the second syringe 20 move synchronously. Specifically, a first clamping groove 41 and a second clamping groove 42 are formed in one side surface of the push rod clamp 40, the first clamping groove 41 can be far away from the end portion of the sleeve with the push rod of the first syringe 10, the second clamping groove 42 can be far away from the end portion of the sleeve with the push rod of the second syringe 20, the push rod clamp 40 is fixedly connected with the push rods of the first syringe 10 and the second syringe 20, and under the driving of the push rod clamp 40, the push rods of the first syringe 10 and the second syringe 20 move synchronously, so that the first syringe 10 and the second syringe 20 can push liquid or extract liquid synchronously.

In some embodiments, as shown in fig. 1 and 11, the pusher grip 40 further includes an annular grip 43, the grip 43 being disposed on a side of the pusher grip 40 remote from the pusher. The user can conveniently hold the push rod clip 40 for operation.

In some embodiments, as shown in fig. 1, the mixing device 30 further comprises an outlet, for example, located on a side of the mixing tube 33 remote from the first branch 31 and the second branch 32. The tissue glue application device 100 further comprises a spray head 60, preferably an atomizing spray head, disposed at the outlet of the mixing device 30, so that the tissue glue output from the tissue glue application device is atomized and sprayed out.

In the tissue cement applying device of the present disclosure, when not in use, the first and

second syringes

10 and 20 may store the first and second liquids for generating the tissue cement, the channel switching assemblies in the first and second branches are in the closed state, i.e., the cock of the channel switching assembly is in the third position, and the first and

second syringes

10 and 20 are not in communication with the first and second passages of their corresponding channel switching assemblies. When the tissue adhesive application device is required to perform tissue adhesive operation, firstly, a penicillin bottle with a first solute and a penicillin bottle with a second solute are mounted on a channel switching assembly of a first branch and a second branch, namely, a needling part of a cock of the channel switching assembly is inserted into the corresponding penicillin bottle, and a first opening on the side wall of the needling part is positioned in the penicillin bottle. Then, the channel switching components in the first branch and the second branch are switched to a first conducting state, namely the cock of the channel switching component is in a first position, the first syringe 10 and the second syringe 20 are communicated to corresponding penicillin bottles through a first passage, the push rod clamps are pushed to enable the push rods of the first syringe 10 and the second syringe 20 to push the liquid in the first syringe 10 and the liquid in the second syringe 20 at the same time, the first liquid and the second liquid in the first syringe 10 and the second syringe 20 are respectively injected into the corresponding penicillin bottles, and the tissue gel applying device can be manually rocked, so that the first liquid and the second liquid are fully reacted with the first solute and the second solute respectively, and a first solution and a second solution are generated. Further, the first syringe 10 and the second syringe 20 are simultaneously withdrawn by pulling the push rod grip, and the first solution and the second solution in the corresponding penicillin bottles are withdrawn into the first syringe 10 and the second syringe 20, respectively. Then, the channel switching assembly in the first branch and the second branch is switched to a second conducting state, namely, the cock of the channel switching assembly is in a second position, the first syringe 10 and the second syringe 20 are communicated to the mixing pipe fitting of the mixing device through the second passage, the push rod clamp is pushed so that the push rods of the first syringe 10 and the second syringe 20 push the first solution and the second solution in the first syringe 10 and the second syringe 20 at the same time, the first solution and the second solution in the first syringe 10 and the second syringe 20 are injected into the mixing pipe fitting of the mixing device, and the two solutions react in the mixing pipe fitting to generate tissue glue. Under the continuous pressure of the pusher grip, the tissue gel is ejected through an ejection head located at the outlet of the mixing device.

Finally, it should be noted that: in the present specification, each embodiment is described in a progressive manner, and each embodiment is mainly described in a different point from other embodiments, and identical and similar parts between the embodiments are all enough to refer to each other. The system or the device disclosed in the embodiments are relatively simple in description, and the relevant points refer to the description of the method section because the system or the device corresponds to the method disclosed in the embodiments.

The above embodiments are merely for illustrating the technical solution of the present disclosure, and are not limiting thereof; although the present disclosure has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present disclosure.

Claims

1. A tissue gel application device, comprising:

a first syringe configured to hold a first liquid;

a second syringe configured to hold a second liquid; and

the channel switching assembly includes:

a storage member having a receiving portion;

2. The tissue gel application device of claim 1, wherein the mixing device further comprises: a mixing pipe which is communicated with the first branch and the second branch,

3. The tissue glue application device of claim 1 or 2, wherein the tap comprises:

the cock body is accommodated in the accommodating part;

4. The tissue glue application device of claim 3, wherein the first passageway further comprises a second opening on a sidewall of the tap body, the second opening interfacing with the first through hole in response to the tap being switched to the first position.

5. The tissue glue application device of claim 4, wherein the needled portion further comprises a first marker extending from the needled portion sidewall in the axial direction of the second opening.

6. The tissue glue application device of claim 3, wherein the second passageway extends within the tap body and includes third and fourth openings on the tap body side wall that interface with the first and second through holes, respectively, in response to the tap being switched to the second position.

7. The tissue glue application device of claim 6, wherein the needled portion further comprises a second identifier extending from the needled portion sidewall in an axial direction of the third opening and a third identifier extending from the needled portion sidewall in an axial direction of the fourth opening.

8. The tissue glue application device of claim 6, wherein the third opening is disposed opposite the fourth opening and both are symmetrical with respect to an axis of the tap body.

9. The tissue glue application device of any one of claims 1-8, wherein the tap is switchable to a third position relative to the receptacle such that a syringe corresponding to the branch is disconnected from both the first passageway and the second passageway.

10. The tissue glue application device of any of claims 1-8, wherein the tissue glue application device further comprises:

11. The tissue gel application device of claim 10, wherein the tissue gel application device further comprises a pusher clip connected to the ends of the pushers of the first and second syringes distal from the cannula such that the pushers of the first and second syringes move in synchrony.

12. The tissue glue application device of claim 11, wherein the pusher grip further comprises an annular handle disposed on a side of the pusher grip remote from the pusher.

13. The tissue glue application device of any of claims 1-8, wherein the mixing device further comprises an outlet, the tissue glue application device comprising a spray head disposed at the outlet of the mixing device.