CN114177510A

CN114177510A - Tissue glue applying device

Info

Publication number: CN114177510A
Application number: CN202111674659.1A
Authority: CN
Inventors: 魏鹏飞; 陈慧军; 王华生; 李学军; 赵博
Original assignee: BEIJING BIOSIS HEALING BIOLOGICAL TECHNOLOGY CO LTD
Current assignee: BEIJING BIOSIS HEALING BIOLOGICAL TECHNOLOGY CO LTD
Priority date: 2021-12-31
Filing date: 2021-12-31
Publication date: 2022-03-15

Abstract

The present disclosure provides a tissue glue application device comprising: two injection assemblies and a mixer; the two injection assemblies are connected with the mixer through injection ports; each injection assembly comprises: an injection housing, a spool, and a push rod; the sliding column is inserted into the injection shell from the opening and can slide along the injection shell; the two ends of the sliding column are respectively an insertion end and a push-pull end; the insertion end is positioned in the injection shell, and the push rod is arranged on the push-pull end; the inserting end is provided with a liquid inlet hole; the push rod is provided with a plug for sealing the liquid inlet hole; the push rod slides relative to the containing cavity so that the plug opens the liquid inlet hole and the injection shell and the containing cavity are communicated through the liquid inlet hole. This is disclosed to be used for saving multiple tissue glue raw materials respectively through two injection assembly, can utilize the push rod sliding action to open the feed liquor hole and make powder and liquid mix and generate tissue glue to be convenient for produce tissue glue immediately and use, realized liquid level intermixing intensive reaction, and the advantage of applying fast.

Description

Tissue glue applying device

Technical Field

The disclosure relates to a medical appliance manufacturing technology, in particular to a tissue glue applying device, and belongs to the technical field of medical article manufacturing.

Background

The medical glue is a new medical product for replacing sewing needles, and the main component of the medical glue is alpha-cyanoacrylate which has the fastest polymerization speed in organism tissues. The medical glue can be rapidly polymerized and solidified into a film under the action of anions in wound surface blood and tissue fluid, is tightly embedded with the wound surface, can firmly keep the involution state of the wound, can prevent blood cells and blood platelets from passing through, can effectively stop bleeding by sealing small blood vessels fractured on the wound surface under the combined action of thrombin and fibrinogen, and has the functions of resisting infection and protecting the wound surface. The ether chain in the polymer also has the function of relieving pain, so the medical glue has the comprehensive effects of adhesion, hemostasis, pain relief, inflammation diminishing, wound protection, healing promotion and the like.

The medical tissue glue is a tissue adhesive, is used for bonding human tissues, and can be directly coated or sprayed on wounds or wound surfaces for wound healing. The medical hydrogel as one kind of tissue glue is one new kind of functional polymer material, which has hydrophilic group, water swellable and water insoluble polymer with three-dimensional network structure. The modified starch has the characteristics of biological safety, modifiability, good mechanical property and the like, and has wide application in the fields of biomedicine, agriculture, industry, environmental protection and the like. In the field of biomedicine, hydrogel can be used as a medical dressing to cover wounds and achieve rapid healing. In addition, the hydrogel can also be used as a drug slow-release carrier, a tissue engineering material, an oral application material and the like, and has very wide application prospect in the biomedical field due to the porosity, softness, high water content and high tissue compatibility. Currently, there are a variety of hydrogel materials in the market for clinical hemostatic sealing.

The medical hydrogel has wide application range and can be applied to various wound surfaces including body surfaces, internal bodies and the like. In the prior art, hydrogel is mainly applied through a double syringe, but the wound surface in a body, especially the wound surface in endoscopic surgery, is rubberized.

Tissue gels, such as medical hydrogels, are prepared by mixing solid and liquid components and then mixing the components at a liquid level to achieve complete and uniform gelling. The use of such well-mixed reaction means results in a faster reaction rate and requires timely application of the hydrogel to the tissue to be treated, thus placing high demands on the applicators of the prior art. Therefore, when tissue glues are used for operations, such as wound coating, it is necessary to use the tissue glues in a ready-to-use, as-produced manner.

The tissue glue in the prior art is generally prepared before the operation and then used; however, due to the fact that the number of configuration components is too large, configuration time is long, and time is not always available for configuration when the configuration components are needed; if the gel is prepared in advance, the prepared gel is easy to be polluted after being placed for a long time, and risks are generated when the gel is used.

Disclosure of Invention

The utility model provides a new tissue glue applying device, through set up the slip cavity that can mix solid-liquid formation gel in the injection subassembly to can dispose tissue glue and injection immediately, in order to solve among the prior art tissue glue can not dispose the technical problem who uses immediately after good immediately.

The tissue glue applying device of the disclosed embodiment comprises: two injection assemblies and a mixer; the two injection assemblies are fixedly connected with each other and are provided with injection ports; both of the injection ports are connected with the mixer;

each of the injection assemblies comprises: an injection housing, a spool, and a push rod; the injection shell is of a cylindrical structure with one end opened, and the other end is provided with the injection port; the sliding column is inserted into the injection shell from the opening and can slide along the injection shell;

the sliding column is provided with a containing cavity with a tubular structure, and an inserting end and a pushing and pulling end are respectively arranged at two ends of the sliding column; the insertion end is positioned in the injection shell, and the push rod is arranged on the push-pull end; one end of the push rod is positioned in the cavity and can slide along the length direction of the cavity;

a liquid inlet hole is formed in the insertion end; the push rod is provided with a plug for sealing the liquid inlet hole; the push rod slides relative to the containing cavity so that the plug opens the liquid inlet hole and the inside of the injection shell is communicated with the containing cavity through the liquid inlet hole.

In some embodiments, the push rods on both of the injection assemblies are parallel to each other.

In some embodiments, the apparatus further comprises: connecting the fixed mount and the pull ring; the two injection assemblies are mutually parallel and fixed on the connecting and fixing frame;

the two sides of the connecting fixing frame are symmetrically provided with pressing handles, and the push rods on the two injection assemblies are fixed on the pull ring.

In some embodiments, a limiting rod is further arranged on the connecting fixing frame; one end of the limiting rod is fixed on the connecting and fixing frame, and the other end of the limiting rod is propped against the pull ring.

In some embodiments, the push rod is provided with a liquid inlet groove; when the plug opens the liquid inlet hole, the liquid inlet groove establishes a liquid flow channel at the liquid inlet hole.

In some embodiments, the spool slides on the inner wall of the injection housing through the seal.

In some embodiments, a sliding hole is arranged on the push-pull end, and the push rod passes through the sliding hole to slide in the cavity; and the push rod is provided with an air inlet groove, and when the plug opens the liquid inlet hole, the air inlet groove establishes an air flow channel at the sliding hole.

In some embodiments, each of the injection ports is provided with an on-off valve, and each of the injection ports is connected to the mixer through the on-off valve.

In some embodiments, the mixer is a Y-mixer having one output port and two input ports in communication with each other; the mixer is respectively connected with the two injection ports through the two input ports;

the output port is provided with a spray head, and the spray head is preferably an atomizer.

In some embodiments, the on-off valve is a one-way valve.

In the embodiment of the disclosure, the two injection assemblies are used for storing various tissue glue raw materials respectively, and the liquid inlet hole can be opened by utilizing the sliding action of the push rod to mix powder and liquid to generate the tissue glue, so that the tissue glue is produced and used immediately, the liquid-level mutual mixing and full reaction are realized, and the advantage of quick application is realized.

The tissue glue applying device disclosed by the invention adopts the sliding columns of the double-injection assembly to contain two tubes of different liquids, and correspondingly adopts the plurality of injection shells to store different types of solutes, so that all raw materials are separated from each other, and the preservation of the tissue glue forming material is facilitated. The mixing action of liquid and holding is realized to the switch that utilizes the feed liquor hole of traveller and injection casing tip, and this disclosure distinguishes the process that liquid mixes with liquid respectively and the process that the liquid in the double injection subassembly mixes into the aquogel to further directly apply after the mixed liquid passes through the blender. The tissue glue is formed and utilized, so that the advantages of liquid-level mutual mixing and full reaction and quick application are realized.

Drawings

In order to more clearly illustrate the embodiments of the present disclosure or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present disclosure, and other drawings can be obtained according to the drawings without creative efforts for those skilled in the art.

FIG. 1 is a block diagram of a tissue glue application device according to an embodiment of the present disclosure;

FIG. 2 is a cross-sectional block diagram of a tissue glue application device according to an embodiment of the present disclosure;

FIG. 3 is a cross-sectional view of another embodiment of the disclosed tissue glue applicator.

Detailed Description

To make the objects, technical solutions and advantages of the present disclosure clearer, the present disclosure will be described in further detail with reference to the accompanying drawings, and it is apparent that the described embodiments are only a part of the embodiments of the present disclosure, rather than all embodiments. All other embodiments, which can be derived by one of ordinary skill in the art from the embodiments disclosed herein without making any creative effort, shall fall within the scope of protection of the present disclosure.

The terminology used in the embodiments of the present disclosure is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. As used in the disclosed embodiments and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise, and "a plurality" typically includes at least two.

It should be understood that the term "and/or" as used herein is merely one type of association that describes an associated object, meaning that three relationships may exist, e.g., a and/or B may mean: a exists alone, A and B exist simultaneously, and B exists alone. In addition, the character "/" herein generally indicates that the former and latter related objects are in an "or" relationship.

It is also noted that the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that an article or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such article or apparatus. Without further limitation, the recitation of an element by the phrase "comprising a" does not exclude the presence of additional like elements in a commodity or device comprising the element.

In the art, tissue gels, such as medical hydrogels, are prepared by mixing solid and liquid components, and then mixing the components at a liquid level to fully react the components, thereby achieving complete and uniform gelling. The use of such well-mixed reaction means results in a faster reaction rate and requires timely application of the hydrogel to the tissue to be treated, thus placing high demands on the applicator. Therefore, when tissue glues are used for operations, such as wound coating, it is necessary to use the tissue glues in a ready-to-use, as-produced manner.

The present disclosure provides a tissue glue application device comprising: two injection assemblies and a mixer; the two injection assemblies are fixedly connected with each other and are provided with injection ports; both of the injection ports are connected with the mixer; each of the injection assemblies comprises: an injection housing, a spool, and a push rod; the injection shell is of a cylindrical structure with one end opened, and the other end is provided with the injection port; the sliding column is inserted into the injection shell from the opening and can slide along the injection shell; the sliding column is provided with a containing cavity with a tubular structure, and an inserting end and a pushing and pulling end are respectively arranged at two ends of the sliding column; the insertion end is positioned in the injection shell, and the push rod is arranged on the push-pull end; one end of the push rod is positioned in the cavity and can slide along the length direction of the cavity; a liquid inlet hole is formed in the insertion end; the push rod is provided with a plug for sealing the liquid inlet hole; the push rod slides relative to the containing cavity so that the plug opens the liquid inlet hole and the inside of the injection shell is communicated with the containing cavity through the liquid inlet hole.

The working principle of the disclosed tissue glue applying device is as follows: the sliding columns of the double-injection assembly are adopted to respectively contain two pipes of liquid, correspondingly 2 injection shells are adopted to store different types of solutes, two sets of mutually independent structures are used for forming the liquid to be mixed to form the tissue glue, all raw materials are mutually separated, and the preservation of the material for forming the tissue glue is facilitated. The mixing action of liquid and solute is realized by utilizing the switch of the liquid inlet hole at the end part of the sliding column and the injection shell, the process that the liquid is respectively mixed with the liquid is distinguished from the process that the liquid in the double-injection component is mixed into the hydrogel, and the mixed liquid is further directly applied after passing through the mixer. The tissue glue is formed and utilized, so that the advantages of liquid-level mutual mixing and full reaction and quick application are realized.

The tissue glue application devices described in the present disclosure may be made of, and are not limited to, the following materials and components, for example: rubber plug, silica gel, plastics, nylon, polytetrafluoroethylene, check valve, atomizer, lead-free glass, plastic support, stop device, etc.

FIG. 1 is a block diagram of a tissue glue application device according to an embodiment of the present disclosure; and in conjunction with figures 2 and 3.

The tissue glue applying device of the disclosed embodiment comprises: two injection assemblies and a mixer 6; the two injection assemblies are fixedly connected with each other and are provided with injection ports; both of the injection ports are connected with the mixer 6; each injection assembly is adapted to mix to produce a mixed solution which, once again, is mixed by mixer 6 to form the desired tissue glue.

Further, as shown in fig. 2, each of the injection ports is provided with a switching valve 10, and each of the injection ports is connected to the mixer 6 through the switching valve 10.

In general, the on-off valves 10 are all check valves to prevent the generated mixed liquid from flowing backward.

Preferably, the mixer 6 is a Y-shaped mixer, having an output port and two input ports communicating with each other; the mixer 6 is respectively connected with the two injection ports through the two input ports; the delivery outlet is provided with a spray head 60, the spray head can be a liquid spray head or an atomizer, and the spray head 60 enables the tissue glue output by the tissue glue applying device to be sprayed out, so that the utilization efficiency of the tissue glue is improved. The atomiser is typically a venturi atomiser. When gas or liquid flows inside the venturi, at the narrowest point of the duct, the dynamic pressure reaches a maximum, the static pressure reaches a minimum, and the velocity of the gas (liquid) rises as the cross-sectional area of the flow decreases. The entire inrush current is subjected to the pipe reduction process at the same time, and the pressure is reduced at the same time. Thereby creating a pressure differential that is used to provide an external suction to the fluid, thereby creating an atomization effect. The venturi tube atomizer is simple in structure and good in using effect.

As shown in fig. 1, each of the injection assemblies comprises: an injection housing 1, a spool 2 and a push rod 3; the injection shell 1 is used for containing and sealing solute and can also contain mixed liquid in the process of injecting the mixed liquid; the slide column 2 is also a closed structure for sealing and storing the liquid that generates the mixed liquid.

Because two sets of injection assemblies are adopted, two different solutes and different liquids can be included, and the four components can be independently stored.

FIG. 2 is a cross-sectional block diagram of a tissue glue application device according to an embodiment of the present disclosure; the injection shell 1 is a cylinder structure with one end open, and the other end is provided with the injection port; the sliding column 2 is inserted into the injection housing 1 from the opening and can slide along the injection housing 1; the spool 2 presses the injection housing's inner space, thereby causing the injection housing 1 to perform an injection function. The two sliding columns 2 are fixedly connected with each other through a connecting fixing frame 8 and move synchronously.

One end of the slide post 2 is adapted to slide within the injection housing 1 to compress the substance within the injection housing 1 to move towards the injection port for the injection effect. That is, the spool acts as a piston of the injection housing, primarily for compressing the volume within the injection housing 1 for the injection effect.

The sliding column 2 is a cavity with a tubular structure, and an insertion end and a push-pull end are respectively arranged at two ends of the cavity; the insertion end is positioned in the injection shell 1, and the push rod 3 is arranged on the push-pull end; one end of the push rod 3 is positioned in the cavity and can slide along the length direction of the cavity; the sliding column 2 is also a closed cavity, and the push rod 3 is used for opening the closed cavity.

FIG. 3 is a cross-sectional view of another embodiment of the disclosed tissue glue applicator. The function of the push rod 3 is only to open or close the inlet opening 22 of the insertion end by axial movement, so as to achieve conduction between the injection housing 1 and the inside of the slide column 2.

The inserting end of the sliding column 2 is provided with a liquid inlet hole 22; the push rod 3 is provided with a plug 30 for sealing the liquid inlet hole 22; the push rod 3 slides relative to the chamber so that the plug 30 opens the liquid inlet hole 22 and the injection housing 1 and the chamber communicate with each other through the liquid inlet hole 22.

The mixing process of the tissue glue application device of the embodiment of the disclosure is as follows:

removing the disclosed tissue glue application device; in the two injection assemblies, the injection shell 1 is filled with solute serving as the inside of the injection shell, the sliding column 2 is internally sealed with liquid, and the end part of the push rod 3 is positioned at the liquid inlet hole 22 to seal the liquid inlet hole 22; a radial sealing structure or an axial abutting sealing structure can be adopted between the push rod 3 and the liquid inlet hole 22, for example, a plug 30 for sealing can be arranged at the front end of the push rod 3 so as to open the liquid inlet hole 22 in the axial direction, and a liquid inlet groove 31 is arranged on the cylindrical radial surface of the push rod 3, when the plug 30 opens the liquid inlet hole 22, the liquid inlet groove 31 corresponds to the liquid inlet hole 22, and then the connection between the cavity of the slide column and the inner cavity of the injection housing 1 is established; the push rod passes through the liquid inlet hole 22 and has a gap in the radial direction with the liquid inlet hole 22, and the gap is formed by the liquid inlet groove 31. In addition, an air inlet groove 32 can be arranged on one side of the push rod 3 at the push-pull end, and when the air inlet groove 32 is arranged at the sliding hole 21 at the push-pull end, the sliding hole 21 can be opened to establish a passage for external air to enter the sliding column. At the moment, the push rod 3 and the pull ring are kept still, so that the liquid inlet hole is kept in an opening state, the two sliding columns 2 are pulled towards the right side, and air is sucked into the sliding columns 2 from the sliding holes 21 at the push-pull ends at the moment due to the reduction of air pressure in the sliding columns 2; meanwhile, the volume in the injection shell 1 is increased, negative pressure is formed in the injection shell 1 due to the action of the one-way valve 10, and liquid in the sliding column 2 quickly flows into the injection shell 1 through the liquid inlet hole 22; at the moment, air is filled in the sliding column 2, mixed liquid formed by solute and liquid is filled in the injection shell 1, then the liquid inlet hole is closed through the push rod, and the mixed liquid in the injection shell 1 can be injected by adopting the sliding column.

In addition, after the liquid is completely injected into the injection housing, the injection housing 1 may be shaken to accelerate the mixing action of the mixed liquid.

In the embodiment of the disclosure, the two injection assemblies are used for storing various tissue glue raw materials respectively, the liquid inlet hole can be opened by utilizing the sliding action of the push rod to enable powder and liquid to be mixed to generate mixed liquid, and the two mixed liquids are regenerated into the tissue glue, so that the tissue glue is produced and used immediately, the liquid-level mutual mixing and sufficient reaction are realized, and the advantages of quick application are realized.

In the actual use process, mutually independent liquids are filled in the sliding column 2 of each injection assembly, and mutually independent solutes are arranged in the injection shell 1 of each injection assembly; after each injection assembly opens the liquid inlet hole through the push rod, liquid and solute are mixed to form mixed liquid, and tissue glue is formed through the mixer.

The tissue glue in the embodiment needs to form two solutions which are mutually independent in space, the solutions are respectively formed by powder and solvent which are mutually independent in space, and because the powder is accommodated in the injection shell 1 and the liquid is sealed in the sliding column 2, the tissue glue can store the liquid and the solute which are mutually separated in space for a long time, and can be simply and quickly generated and applied when operation is carried out.

The tissue glue application device of the present embodiment, wherein the push rods 3 of the two injection assemblies are parallel to each other. Therefore, in the operation process, the two liquid inlet holes can be opened through the push rod, and the sliding column can be pushed in the force applying direction, so that the glue applying process can be conveniently injected.

At the moment, the opening or closing of the liquid inlet holes in the two injection assemblies can be finished by adopting the same action, so that the operation is facilitated to the maximum extent.

Preferably, as shown in fig. 1, the tissue glue applying apparatus of the present embodiment further includes: connecting the fixed mount 4 and the pull ring 5; the two injection assemblies are mutually parallel and fixed on the connecting and fixing frame 4; connecting the mount 4 can guarantee that two injection components are parallel and level each other, and the injection mouth all links to each other with blender 6 towards one end.

The two sides of the connecting and fixing frame 4 are also symmetrically provided with pressing handles 40, and the push rods 3 on the two injection assemblies are fixed on the pull ring 5.

In the production process, because the two injection assemblies have the same structure, the injection assemblies can be produced in batch; then install injection unit side by side on connecting mount 4, then install the pull ring and can accomplish production assembly process on the push rod, simple swift.

In the process of producing mixed liquid in actual use, the pull ring 5 is pushed to the left side, and after the liquid inlet hole is opened, the solute and the liquid are mixed to form the mixed liquid; during the injection, the finger abuts against the handle 40, and the thumb pushes the pull ring 5, so that the push rod drives the slide column 2 to extrude into the injection housing 1, so as to complete the injection.

Fig. 1 is a structural diagram of the tissue glue applying device according to the embodiment of the present disclosure, and the connecting fixing frame 4 is further provided with a limiting rod 7; one end of the limiting rod 7 is fixed on the connecting and fixing frame 4, and the other end of the limiting rod is propped against the pull ring 5.

Specifically, one end of the limiting rod 7 is provided with a clamping seat 70, and is fixed on the connecting and fixing frame 4 through the clamping seat 70; the other end of the limiting rod 7 is abutted against the pull ring 5, so that the sliding column 2 is prevented from being pushed by the pull ring 5 in the process of producing mixed liquid, and the incompletely-reacted mixed liquid is injected in advance.

In the process of producing the mixed liquid, the liquid inlet hole and the sliding hole can be opened only by pulling the push rod to the right side, and extra operation on the sliding column is not needed. At the moment, although the liquid inlet hole is opened, the liquid can be only partially mixed in the liquid inlet hole; liquid cannot actively flow from the spool 2 into the injection housing 1; the limiting rod 7 can also ensure that the state of the sliding column does not extrude the injection shell 1 to the left side; keeping the push rod 3 and the pull ring still at the moment so as to keep the liquid inlet hole in an opening state, pulling the two sliding columns 2 towards the right side, and sucking air into the sliding columns 2 from the push-pull ends at the moment due to the reduction of air pressure in the sliding columns 2; meanwhile, the volume in the injection shell 1 is increased, and liquid quickly flows into the injection shell 1 from the liquid inlet hole; at the moment, air is filled in the sliding column 2, mixed liquid formed by solute and liquid is filled in the injection shell 1, then the liquid inlet hole is closed through the push rod, and the mixed liquid in the injection shell 1 can be injected by adopting the sliding column.

In the injection process, the sliding column can perform injection operation sliding towards the right side relative to the injection shell 1 only by taking down the limiting rod 7.

In this embodiment, as shown in fig. 2 and 3, a sealing plug 20 is disposed on the insertion end of the sliding column 2, and the liquid inlet hole is opened on the sealing plug 20; the sealing plug 20 is a generally cylindrical rubber sealing plug for pushing the mixture in the injection housing 1 during the injection process.

The plug 30 and the sealing plug 20 are mutually matched, so that the liquid inlet hole can be opened or closed.

Typically, the sliding column 2 slides on the inner wall of the injection housing 1 via the sealing plug 20.

In the use, sealing plug 20 has not only played the mesh of sealed traveller 2 and injection casing 1, can also effectual parcel and block the feed liquor hole, avoids opening the feed liquor hole in advance to further avoid the maloperation.

The whole working process of the tissue glue applying device in the embodiment of the disclosure is as follows:

1. in the two injection assemblies of the present disclosure, the injection housing 1 is filled with solute, and the inside of the spool 2 is sealed with liquid; the liquid and solute in both syringe assemblies are separated from each other. At the moment, the plug 30 of the push rod 3 is positioned in the sealing plug 20 to seal the liquid inlet hole, so that the solute is prevented from contacting with the liquid in advance;

2. pushing the push rod 3 to the left side to remove the plug 30 from the sealing plug 20 so as to open the liquid inlet hole; although the liquid inlet hole is opened at the moment, liquid cannot enter the injection shell 1 because the pressures at the two ends of the liquid inlet hole are balanced;

3. keeping the push rod 3 and the pull ring to be relatively static with the sliding columns, pulling the two sliding columns 2 towards the right side, and sucking air into the sliding columns 2 from the sliding holes 21 through the air inlet grooves 32 at the moment due to the reduction of air pressure in the sliding columns 2; meanwhile, the volume in the injection shell 1 is increased, the air pressure is reduced, and liquid quickly flows into the injection shell 1 from the liquid inlet hole through the liquid inlet groove 31; the entire strut 2 is now air.

4. The push rod is pulled to seal the liquid inlet hole, and the mixture liquid is shaken to accelerate the mixing action of the mixture liquid in the injection shell 1;

5. inverting the whole device, and slightly discharging the redundant air in the injection shell 1 by slightly pushing the sliding column 2; removing the limiting rod 7;

6. the sliding column 2 is pushed, so that the mixed liquid in the injection shell enters the mixer 6 through the one-way valve and enters the spray head 60 to be sprayed after being mixed.

In addition, the tissue glue applying device disclosed by the invention is low in manufacturing cost, small and exquisite, compact in structural design, stable in finished product quality, convenient and quick to use and operate, and suitable for instant storage and configuration of various modified tissue glues and medical gels.

The above-mentioned serial numbers of the embodiments of the present disclosure are merely for description and do not represent the merits of the embodiments. Through the above description of the embodiments, those skilled in the art will clearly understand that the above embodiment method can be implemented by some modifications plus the necessary general technical overlap; of course, the method can also be realized by simplifying some important technical features in the upper level. Based on such understanding, the technical solution of the present disclosure essentially or contributing to the prior art is: the whole structure and the connection mode are matched with the structure of each embodiment of the disclosure.

Finally, it should be noted that: the above embodiments are only used for illustrating the technical solutions of the present disclosure, and not for limiting the same; while the present disclosure has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art will understand that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present disclosure.

Claims

1. A tissue glue application device, comprising: two injection assemblies and a mixer; the two injection assemblies are fixedly connected with each other and are provided with injection ports; both of the injection ports are connected with the mixer;

2. The tissue gel application apparatus of claim 1, wherein the push rods on both of the injection assemblies are parallel to each other.

3. The tissue gel application apparatus of claim 2, further comprising: connecting the fixed mount and the pull ring; the two injection assemblies are mutually parallel and fixed on the connecting and fixing frame;

4. The tissue glue application device according to claim 3, wherein a stop bar is further provided on the connection holder; one end of the limiting rod is fixed on the connecting and fixing frame, and the other end of the limiting rod is propped against the pull ring.

5. The tissue glue applicator according to any one of claims 1 to 4, wherein the push rod is provided with a liquid inlet groove; when the plug opens the liquid inlet hole, the liquid inlet groove establishes a liquid flow channel at the liquid inlet hole.

6. The tissue gel application device of claim 5, wherein the sliding post slides on an inner wall of the injection housing via the sealing plug.

7. The tissue glue applicator according to any one of claims 1 to 4, wherein a sliding hole is formed on the push-pull end, and the push rod passes through the sliding hole to slide in the accommodating cavity;

and the push rod is provided with an air inlet groove, and when the plug opens the liquid inlet hole, the air inlet groove establishes an air flow channel at the sliding hole.

8. The tissue glue application device according to any one of claims 1 to 4, wherein each injection port is provided with an on-off valve, and each injection port is connected to the mixer through the on-off valve.

9. The tissue glue application device according to any one of claims 1 to 4, wherein the mixer is a Y-shaped mixer having one output port and two input ports in communication with each other; the mixer is respectively connected with the two injection ports through the two input ports;

10. The tissue gel application device of claim 8, wherein the on-off valve is a one-way valve.