CN116211401A - Vortex ultrasonic thrombolysis device - Google Patents
Vortex ultrasonic thrombolysis device Download PDFInfo
- Publication number
- CN116211401A CN116211401A CN202310340595.4A CN202310340595A CN116211401A CN 116211401 A CN116211401 A CN 116211401A CN 202310340595 A CN202310340595 A CN 202310340595A CN 116211401 A CN116211401 A CN 116211401A
- Authority
- CN
- China
- Prior art keywords
- ultrasonic
- thrombolysis
- target
- vortex
- ultrasonic element
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002537 thrombolytic effect Effects 0.000 title claims abstract description 62
- 238000004382 potting Methods 0.000 claims abstract description 9
- 239000000919 ceramic Substances 0.000 claims description 19
- 239000003146 anticoagulant agent Substances 0.000 claims description 15
- 239000004642 Polyimide Substances 0.000 claims description 6
- 229920001721 polyimide Polymers 0.000 claims description 6
- -1 polytetrafluoroethylene Polymers 0.000 claims description 6
- 230000000712 assembly Effects 0.000 claims description 5
- 238000000429 assembly Methods 0.000 claims description 5
- 239000004814 polyurethane Substances 0.000 claims description 5
- 230000003321 amplification Effects 0.000 claims description 4
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 4
- 239000004593 Epoxy Substances 0.000 claims description 3
- 239000004698 Polyethylene Substances 0.000 claims description 3
- 229920000573 polyethylene Polymers 0.000 claims description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 3
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 3
- 229920002635 polyurethane Polymers 0.000 claims description 3
- 229920003225 polyurethane elastomer Polymers 0.000 claims description 3
- 229920002379 silicone rubber Polymers 0.000 claims description 3
- 239000004945 silicone rubber Substances 0.000 claims description 3
- 230000005540 biological transmission Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 9
- 208000007536 Thrombosis Diseases 0.000 description 10
- 238000002604 ultrasonography Methods 0.000 description 9
- 238000000034 method Methods 0.000 description 6
- 238000012986 modification Methods 0.000 description 6
- 230000004048 modification Effects 0.000 description 6
- 230000006378 damage Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000010008 shearing Methods 0.000 description 3
- 241000282414 Homo sapiens Species 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000028389 Nerve injury Diseases 0.000 description 1
- 208000010378 Pulmonary Embolism Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 206010053648 Vascular occlusion Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 238000002399 angioplasty Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 230000008764 nerve damage Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 208000021331 vascular occlusion disease Diseases 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
- A61B17/2202—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement the ultrasound transducer being inside patient's body at the distal end of the catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
- A61B2017/22084—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance stone- or thrombus-dissolving
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Mechanical Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The application provides an eddy current ultrasonic thrombolysis device, which relates to the technical field of medical equipment. The vortex ultrasonic thrombolysis device comprises a host and a catheter which are connected, wherein an ultrasonic element is arranged in an end pipe of the catheter, a gap between the ultrasonic element and the inner wall of the end pipe is filled with a potting medium, the potting medium is used for fixing the ultrasonic element and has an ultrasonic wave propagation function, the host is used for driving and controlling the ultrasonic element to work in real time, the catheter is used for delivering the ultrasonic element to a target thrombolysis position, and different ultrasonic emission positions on the ultrasonic element respectively emit ultrasonic waves to reach the target thrombolysis position and have a phase difference, so that the efficiency of damaging target tissues by the ultrasonic waves is improved, and the thrombolysis effect is optimized.
Description
Technical Field
The application relates to the technical field of medical equipment, in particular to an eddy-current ultrasonic thrombolysis device.
Background
Thrombus is one of the common clinical diseases, and the thrombosis often causes peripheral vascular occlusion, serious dangerous diseases such as ischemic cerebral apoplexy, myocardial infarction, pulmonary embolism and the like, and seriously endangers the life and health of human beings. The traditional methods for thrombolysis, balloon interventional angioplasty or surgical operation thrombolysis have obvious defects, the injury to patients caused by operation thrombolysis is large, the time window of thrombolysis is short, the success rate is low, and complications such as nerve injury and internal hemorrhage of tissues are often caused.
And researches show that the mechanical effect and cavitation effect of the ultrasonic waves can accelerate the breaking and dissolution of thrombus. The ultrasonic thrombolysis technology has the characteristics of high thrombolysis efficiency and good safety, and has attractive application prospect. However, most of the existing ultrasonic thrombolysis technologies adopt plane wave mode for treatment, and the thrombus is gradually broken by means of the tensile stress and the compressive stress of the mechanical wave which cause the reciprocating cycle in the thrombus, and the tensile stress and the compressive stress of the reciprocating cycle are often insufficient for destroying the internal structure aiming at the old thrombus.
Disclosure of Invention
In view of this, the embodiments of the present disclosure provide an eddy current ultrasonic thrombolysis device, which improves the efficiency of ultrasonic destruction of target tissue and optimizes thrombolysis effect.
The embodiment of the specification provides the following technical scheme:
the vortex ultrasonic thrombolysis device comprises a host and a catheter which are connected, wherein an ultrasonic element is arranged in an end pipe of the catheter, a gap between the ultrasonic element and the inner wall of the end pipe is filled with a potting medium, the potting medium is used for fixing the ultrasonic element and has an ultrasonic wave propagation function, the host is used for driving and controlling the ultrasonic element to work in real time, the catheter is used for delivering the ultrasonic element to a target thrombolysis position, and different ultrasonic emission positions on the ultrasonic element respectively emit ultrasonic waves to reach the target thrombolysis position and have phase differences.
In some embodiments, the shape of the ultrasound element comprises a cube, cuboid, cylinder, triangle, round tube, or sheet.
In some embodiments, the ultrasonic element comprises a plurality of piezoelectric ceramic components arranged in a predetermined arrangement, the plurality of piezoelectric ceramic components being integrally connected by a decoupling medium.
In some embodiments, the ultrasound element comprises four piezo-ceramic components, each square, arranged in a 2 x 2 array.
In some embodiments, the four piezoelectric ceramic assemblies each have a different height from the four top surfaces extending outwardly in the direction of the end tube centerline such that the four top surfaces are each at a different target spacing from the target thrombolytic site.
In some embodiments, the target distance from the target thrombolytic site is a distance value corresponding to half wavelength of the emitted ultrasound.
In some embodiments, the square sides of the piezoceramic assembly are 0.8mm long.
In some embodiments, the host includes a frequency control module and a power amplification module for driving the ultrasonic element to emit ultrasonic waves of a preset frequency or preset power.
In some embodiments, the host computer further comprises a circuit module for realizing that different ultrasound emission sites on the ultrasound element respectively emit ultrasound waves with different phase angles reaching the target thrombolysis site through phase control.
In some embodiments, the potting medium is made of epoxy, polyurethane or silicone rubber, and/or the catheter is made of polyimide, polyurethane, polytetrafluoroethylene, polyethylene or woven polyimide; and/or the catheter has a dimension of 3mm outside diameter and 2.6mm inside diameter.
Compared with the prior art, the beneficial effects that above-mentioned at least one technical scheme that this description embodiment adopted can reach include at least: the ultrasonic element is driven by the host computer and is controlled to work in real time, the catheter delivers the ultrasonic element to the target thrombolysis position to dissolve thrombus, and different ultrasonic emission positions on the ultrasonic element respectively emit ultrasonic waves to reach the target thrombolysis position and have phase differences, so that shearing force is formed between adjacent sound field areas, the efficiency of damaging target tissues by ultrasonic waves is improved, and the thrombolysis effect is optimized.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic structural diagram of an eddy current ultrasonic thrombolysis device provided in an embodiment of the present application;
fig. 2 is a schematic structural view of an ultrasonic original in an end tube according to an embodiment of the present application.
Detailed Description
Embodiments of the present application are described in detail below with reference to the accompanying drawings.
Other advantages and effects of the present application will become apparent to those skilled in the art from the present disclosure, when the following description of the embodiments is taken in conjunction with the accompanying drawings. It will be apparent that the described embodiments are only some, but not all, of the embodiments of the present application. The present application may be embodied or carried out in other specific embodiments, and the details of the present application may be modified or changed from various points of view and applications without departing from the spirit of the present application. It should be noted that the following embodiments and features in the embodiments may be combined with each other without conflict. All other embodiments, which can be made by one of ordinary skill in the art based on the embodiments herein without making any inventive effort, are intended to be within the scope of the present application.
It is noted that various aspects of the embodiments are described below within the scope of the following claims. It should be apparent that the aspects described herein may be embodied in a wide variety of forms and that any specific structure and/or function described herein is merely illustrative. Based on the present application, one skilled in the art will appreciate that one aspect described herein may be implemented independently of any other aspect, and that two or more of these aspects may be combined in various ways. For example, apparatus may be implemented and/or methods practiced using any number and aspects set forth herein. In addition, such apparatus may be implemented and/or such methods practiced using other structure and/or functionality in addition to one or more of the aspects set forth herein.
It should also be noted that the illustrations provided in the following embodiments merely illustrate the basic concepts of the application by way of illustration, and only the components related to the application are shown in the drawings and are not drawn according to the number, shape and size of the components in actual implementation, and the form, number and proportion of the components in actual implementation may be arbitrarily changed, and the layout of the components may be more complicated.
In addition, in the following description, specific details are provided in order to provide a thorough understanding of the examples. However, it will be understood by those skilled in the art that the present invention may be practiced without these specific details.
The following describes the technical solutions provided by the embodiments of the present application with reference to the accompanying drawings.
As shown in fig. 1 and 2, the vortex ultrasonic thrombolysis device provided in the embodiment of the present disclosure includes a main unit 1 and a catheter 2 connected to each other, an ultrasonic element 31 is disposed in an end tube 33 of the catheter 2, a gap between the ultrasonic element 31 and an inner wall of the end tube 33 is filled with a potting medium 32, the potting medium 32 is used for fixing the ultrasonic element 31 and has an ultrasonic propagation function, the main unit 1 is used for driving and controlling the operation of the ultrasonic element 31 in real time, the catheter 2 is used for delivering the ultrasonic element 31 to a target thrombolysis site to dissolve thrombus, and different ultrasonic emission sites on the ultrasonic element 31 respectively emit ultrasonic waves having a phase difference when reaching the target thrombolysis site.
In some embodiments, the shape of the ultrasonic element 31 may be square, rectangular, cylindrical, triangular, round tubular, sheet-like, or any other feasible shape. The ultrasonic element 31 is a core device for emitting ultrasonic, the size of the ultrasonic element 31 determines the ultrasonic frequency, and the manufacturing process level determines the performance of the ultrasonic element, so that the ultrasonic element 31 is preferably made of piezoelectric ceramic, more preferably made of piezoelectric ceramic P81, and has the characteristics of high power and excellent stability, thereby meeting the expected ultrasonic radiation requirement. In some embodiments, the ultrasound element 31 comprises a plurality of piezo ceramic components arranged in a predetermined arrangement, the plurality of piezo ceramic components being connected together by a decoupling medium (preferably a relatively soft-textured decoupling medium), i.e. the ultrasound element 31 may also be an array structure of smaller ultrasound components. In some embodiments, as shown in fig. 2, the ultrasonic element 31 comprises four piezo-ceramic components, each of which is square, arranged in a 2 x 2 array. In some embodiments, the square sides of the piezoceramic assembly are 0.8mm long.
In some embodiments, the material of the potting medium 32 between the ultrasonic element 31 and the inner wall of the end tube 33 may be a material with excellent sound transmission performance and acoustic impedance close to that of human blood, and preferably an epoxy rubber, polyurethane rubber or silicone rubber. In some embodiments, the catheter 2 may be made of a material having sufficient flexibility, kink resistance and structural support properties, because a certain structural strength can support the catheter 2 body to the treatment site, and also has the ability to transmit torque, preferably polyimide, polyurethane, polytetrafluoroethylene, polyethylene, woven polyimide, or the like. In some embodiments, the catheter 2 may be sized to have an outer diameter of 3mm and an inner diameter of 2.6mm.
In some embodiments, the heights of the four top surfaces of the four piezoceramic assemblies extending outwardly in the direction of the centerline of the end tube 33 are all different, such that the target spacing of the four top surfaces from the target thrombolytic site is all different. When the distance between the top surface of each piezoelectric ceramic component and the target thrombolysis (thrombus) position is the same, the ultrasonic wave is transmitted to the target thrombolysis position to cause reciprocating vibration (the phase angle is the same) of the target, and cyclic tensile stress and compressive stress are formed inside the target; when the distances between the top surfaces of the adjacent piezoelectric ceramic components and the target thrombolysis position are different, the distance value corresponding to the half wavelength is preferable, and because the phase angles of the adjacent piezoelectric ceramic components when the ultrasonic waves are radiated to reach the target thrombolysis position are different, shearing force is formed between the adjacent sound field areas, so that the efficiency of damaging target tissues by the ultrasonic waves is further improved, and the thrombolysis effect is optimized.
In some embodiments, the host 1 includes a frequency control module (not shown in the figure) and a power amplification module (not shown in the figure), where the frequency control module and the power amplification module are used to drive the ultrasonic element 31 to emit ultrasonic waves with a preset frequency or preset power, and the preset frequency or preset power may be a specific frequency or specific power that can meet the thrombolysis requirement, and may be selected according to the actual situation, which is not particularly limited in the embodiments of the present application. In some embodiments, the host 1 further includes a circuit module (not shown in the figure), where the circuit module is configured to implement, through phase control (specifically combined with phase control technology), that phase angles of the ultrasonic waves emitted by different ultrasonic emission sites on the ultrasonic element 31 reaching the target thrombolytic site are different, that is, whether heights of top surfaces of the different ultrasonic emission sites on the ultrasonic element 31 are the same or not, phase differences between the plurality of ultrasonic emission sites can be implemented, so that phase angles of the ultrasonic waves emitted by the respective ultrasonic emission sites when reaching the target thrombolytic site are different, and further, a shear force is formed between adjacent sound field regions, thereby achieving the intended high thrombolytic efficiency.
In summary, the vortex ultrasonic thrombolysis device provided in the embodiments of the present application has at least the following beneficial effects:
1. the ultrasonic element is driven by the host computer and is controlled to work in real time, the catheter delivers the ultrasonic element to the target thrombolysis position to dissolve thrombus, and different ultrasonic emission positions on the ultrasonic element respectively emit ultrasonic waves to reach the target thrombolysis position and have phase differences, so that shearing force is formed between adjacent sound field areas, the efficiency of damaging target tissues by the ultrasonic waves is improved, and the thrombolysis effect is optimized;
2. the heights of the four top surfaces extending outwards along the central line direction of the end pipe are different through the four piezoelectric ceramic components, so that the target distances between the four top surfaces and the target thrombolysis part are different, and the efficiency of ultrasonic destruction of target tissues and thrombolysis effect are further improved;
3. the circuit module combined with the host machine realizes that the phase angles of the ultrasonic waves transmitted by different ultrasonic transmitting parts on the ultrasonic element to the target thrombolysis part are different through phase control, and the efficiency of damaging the target tissue by the ultrasonic waves can be improved.
In this specification, identical and similar parts of the embodiments are referred to each other, and each embodiment focuses on the differences from the other embodiments. In particular, for the product embodiments described later, since they correspond to the methods, the description is relatively simple, and reference is made to the description of parts of the system embodiments.
Meanwhile, the specification uses specific words to describe the embodiments of the specification. Reference to "one embodiment," "an embodiment," and/or "some embodiments" means that a particular feature, structure, or characteristic is associated with at least one embodiment of the present description. Thus, it should be emphasized and should be appreciated that two or more references to "an embodiment" or "one embodiment" or "an alternative embodiment" in various positions in this specification are not necessarily referring to the same embodiment. Furthermore, certain features, structures, or characteristics of one or more embodiments of the present description may be combined as suitable.
Furthermore, the order in which the elements and sequences are processed, the use of numerical letters, or other designations in the description are not intended to limit the order in which the processes and methods of the description are performed unless explicitly recited in the claims. While certain presently useful inventive embodiments have been discussed in the foregoing disclosure, by way of various examples, it is to be understood that such details are merely illustrative and that the appended claims are not limited to the disclosed embodiments, but, on the contrary, are intended to cover all modifications and equivalent arrangements included within the spirit and scope of the embodiments of the present disclosure. For example, while the system components described above may be implemented by hardware devices, they may also be implemented solely by software solutions, such as installing the described system on an existing processing device or mobile device.
While the basic concepts have been described above, it will be apparent to those skilled in the art that the foregoing detailed disclosure is by way of example only and is not intended to be limiting. Although not explicitly described herein, various modifications, improvements, and adaptations to the present disclosure may occur to one skilled in the art. Such modifications, improvements, and modifications are intended to be suggested within this specification, and therefore, such modifications, improvements, and modifications are intended to be included within the spirit and scope of the exemplary embodiments of the present invention.
Claims (10)
1. The utility model provides a vortex supersound thrombolysis device which characterized in that, includes host computer and pipe that is connected, be equipped with the ultrasonic element in the tip intraductal of pipe the ultrasonic element with the clearance between the tip intraductal wall is filled with the embedment medium, the embedment medium is used for fixing the ultrasonic element and has the ultrasonic wave propagation function, the host computer is used for driving and real-time control the work of ultrasonic element, the pipe is used for with the ultrasonic element delivers to target thrombolysis position, different supersound transmission positions on the ultrasonic element respectively transmit the ultrasonic wave and have the phase difference when reaching target thrombolysis position.
2. The vortex ultrasonic thrombolytic device of claim 1 wherein the shape of the ultrasonic element comprises a cube, a cuboid, a cylinder, a triangle, a round tube, or a sheet.
3. The vortex ultrasonic thrombolytic device according to claim 1 wherein said ultrasonic element comprises a plurality of piezoelectric ceramic components arranged in a predetermined arrangement, a plurality of said piezoelectric ceramic components being integrally connected by a decoupling medium.
4. A vortex ultrasonic thrombolytic device according to claim 3 wherein said ultrasonic element comprises four piezo-ceramic assemblies each square, four of said piezo-ceramic assemblies being arranged in a 2 x 2 array.
5. The vortex ultrasonic thrombolytic device according to claim 4 wherein the four piezoelectric ceramic assemblies each have a different height of four top surfaces extending outwardly in the direction of the centerline of the end tube such that the four top surfaces are each at a different target spacing from the target thrombolytic site.
6. The vortex ultrasonic thrombolytic device of claim 5 wherein the target distance from the target thrombolytic site is a distance value corresponding to half wavelength of the emitted ultrasonic waves.
7. The vortex ultrasonic thrombolytic device according to any of claims 4 to 6 wherein the square side of said piezoelectric ceramic assembly is 0.8mm.
8. The vortex ultrasonic thrombolysis device according to claim 1 wherein said host comprises a frequency control module and a power amplification module for driving said ultrasonic element to emit ultrasonic waves of a preset frequency or preset power.
9. The vortex ultrasonic thrombolysis device according to claim 8 wherein the host computer further comprises a circuit module for realizing different phase angles of ultrasonic waves emitted by different ultrasonic emission sites on the ultrasonic element to reach the target thrombolysis site respectively by phase control.
10. The vortex ultrasonic thrombolytic device according to any of claims 1 to 6, 8 and 9 wherein the potting medium is epoxy, polyurethane or silicone rubber and/or the catheter is polyimide, polyurethane, polytetrafluoroethylene, polyethylene or woven polyimide; and/or the catheter has a dimension of 3mm outside diameter and 2.6mm inside diameter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310340595.4A CN116211401A (en) | 2023-03-31 | 2023-03-31 | Vortex ultrasonic thrombolysis device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310340595.4A CN116211401A (en) | 2023-03-31 | 2023-03-31 | Vortex ultrasonic thrombolysis device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116211401A true CN116211401A (en) | 2023-06-06 |
Family
ID=86571445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310340595.4A Pending CN116211401A (en) | 2023-03-31 | 2023-03-31 | Vortex ultrasonic thrombolysis device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116211401A (en) |
-
2023
- 2023-03-31 CN CN202310340595.4A patent/CN116211401A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20210007759A1 (en) | Ultrasound transducer and array for intravascular thrombolysis | |
| US20210316334A1 (en) | Method and system for generating mechanical pulses | |
| US6733451B2 (en) | Apparatus and method for an ultrasonic probe used with a pharmacological agent | |
| US6228046B1 (en) | Catheters comprising a plurality of oscillators and methods for their use | |
| US8292835B1 (en) | Non-invasive ultrasonic soft-tissue treatment method | |
| CN1901837B (en) | Component ultrasound transducer | |
| US20140073995A1 (en) | Histotripsy therapy system | |
| US9566079B2 (en) | Single probe with disturber | |
| Zocchi | Basic physics for ultrasound-assisted lipoplasty | |
| WO2005034793A2 (en) | Apparatus and method for an ultrasonic medical device with a non-compliant balloon | |
| WO2004098426A1 (en) | Apparatus and method for preshaped ultrasonic probe | |
| JP2008541843A (en) | Intravascular ultrasound catheter device and method for removing atheroma | |
| US20100057097A1 (en) | Micro-emulsifier for arterial thrombus removal | |
| CN113331912B (en) | Vibration actuator for removing cerebral thrombosis and thrombus removing equipment | |
| CN116211401A (en) | Vortex ultrasonic thrombolysis device | |
| AU2008361369B2 (en) | Micro-emulsifier for arterial thrombus removal | |
| CN111437007A (en) | Ultrasonic structure | |
| Dadgar et al. | High-power phased-array transducer module for the construction of a system for the treatment of deep vein thrombosis | |
| CN113729855A (en) | Insertion type combined ultrasonic thrombolysis device | |
| TW202142192A (en) | Ultrasonic probes for producing multiple cavitation volumes | |
| US20040210140A1 (en) | Apparatus and method for preshaped ultrasonic probe | |
| Woodacre et al. | A 5 mm× 5 mm square, aluminum lens based histotripsy transducer: Reaching the endoscopic form factor | |
| CN221771247U (en) | Guide wire drag reduction system | |
| Zhang et al. | Integration of Forward-viewing and Side-viewing Ultrasound Transducers in an Intravascular Sonothrombolysis Catheter | |
| WO2004096061A1 (en) | Ultrasonic probe used with a pharmacological agent |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |