CN116190195B - Mass spectrometer detection reagent business turn over device and mass spectrometer - Google Patents

Mass spectrometer detection reagent business turn over device and mass spectrometer Download PDF

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Publication number
CN116190195B
CN116190195B CN202310460547.9A CN202310460547A CN116190195B CN 116190195 B CN116190195 B CN 116190195B CN 202310460547 A CN202310460547 A CN 202310460547A CN 116190195 B CN116190195 B CN 116190195B
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China
Prior art keywords
bin
plate
mass spectrometer
outlet
detection reagent
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CN202310460547.9A
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CN116190195A (en
Inventor
张贤栋
李惠静
吴彦超
徐华
张家苒
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Sichuan Mass Spectrometry Biotechnology Co ltd
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Sichuan Mass Spectrometry Biotechnology Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02WCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W30/00Technologies for solid waste management
    • Y02W30/10Waste collection, transportation, transfer or storage, e.g. segregated refuse collecting, electric or hybrid propulsion

Abstract

The invention discloses a mass spectrometer detection reagent inlet and outlet device and a mass spectrometer, and relates to the technical field of mass spectrometers. A bin opening is arranged at one side of the reagent inlet and outlet bin, a bin door is arranged at the bin opening, and the bottom of the bin door is hinged with the reagent inlet and outlet bin; the top of the storage tray is provided with a plurality of grooves, the grooves are used for accommodating corresponding detection reagent bottles, and the width of the storage tray is consistent with the width of the bin opening; the push-pull mechanism is arranged in the reagent inlet and outlet bin and used for enabling the object placing disc to move between the bin opening and the reagent inlet and outlet bin; the lifting mechanism is arranged in the reagent feeding and discharging bin and comprises a hydraulic lifting rod and a lifting plate, the top of the hydraulic lifting rod is arranged on the first support, the bottom of the hydraulic lifting rod is connected with the lifting plate, and a plurality of liquid taking pipes are distributed on the lifting plate and are used for being inserted into corresponding detection reagent bottles. The automatic insertion and extraction of the reagent bottle in and out of the mass spectrometer and the liquid taking pipe can be realized.

Description

Mass spectrometer detection reagent business turn over device and mass spectrometer
Technical Field
The invention relates to the technical field of mass spectrometers, in particular to a mass spectrometer detection reagent inlet and outlet device and a mass spectrometer.
Background
Mass spectrometers are capable of bombarding sample molecules with a stream of energetic electrons or the like, causing the molecules to lose electrons and become positively charged molecular ions and fragment ions. The different ions have different masses and the time for the ions of different masses to reach the detector under the influence of the magnetic field is different, as a result of which a mass spectrum is obtained. The compounds participate in derivatization reactions, which deviate in solubility, boiling point, melting point, aggregation state, or chemical composition, and thus new chemical properties can be quantified or isolated, by which characteristics, in mass spectrometry, substances that are difficult to analyze can be converted into substances that are similar in chemical structure to but easy to analyze, such as chromophores can be added to the detected substances when they are not uv-absorbing, thereby facilitating detection. In the mass spectrometer, a plurality of reagent bottles are internally provided with different detection reagents, each reagent bottle is internally provided with a liquid taking pipe for sucking the corresponding detection reagent and mixing the sample to be detected, the problem is that when a new reagent bottle is replaced each time, a cover of the mass spectrometer is required to be opened, the plurality of liquid taking pipes are pulled out, the liquid taking pipes are sequentially inserted after the new reagent bottle is replaced, the whole process is time-consuming, and the risk of wrong insertion of the liquid taking pipes exists.
Disclosure of Invention
In order to solve the defects in the prior art, the invention provides a mass spectrometer detection reagent inlet and outlet device and a mass spectrometer, which can realize automatic inlet and outlet of a reagent bottle in the mass spectrometer and automatic insertion and extraction of a liquid taking pipe.
In order to achieve the object of the invention, the following scheme is adopted:
a mass spectrometer detection reagent inlet and outlet device comprises a reagent inlet and outlet bin, a storage disc, a plurality of liquid taking pipes, a lifting mechanism and a push-pull mechanism.
A bin opening is arranged at one side of the reagent inlet and outlet bin, a bin gate is arranged at the bin opening, the bottom of the bin gate is hinged to the reagent inlet and outlet bin, and when the bin gate is unfolded, the top surface of the bin gate is flush with the bottom of the reagent inlet and outlet bin;
the top of the storage tray is provided with a plurality of grooves, the grooves are used for accommodating corresponding detection reagent bottles, and the width of the storage tray is consistent with the width of the bin opening;
the push-pull mechanism is arranged in the reagent inlet and outlet bin and used for enabling the object placing disc to move between the bin opening and the reagent inlet and outlet bin;
the lifting mechanism is arranged in the reagent feeding and discharging bin and comprises a hydraulic lifting rod and a lifting plate, the top of the hydraulic lifting rod is arranged on the first support, the bottom of the hydraulic lifting rod is connected with the lifting plate, and a plurality of liquid taking pipes are distributed on the lifting plate and are used for being inserted into corresponding detection reagent bottles.
Further, the one end of putting the thing dish towards the storehouse mouth is equipped with the flange, and the flange bottom flushes with putting the thing dish bottom, and the flange top is equipped with the arc wall.
Further, push-and-pull mechanism includes regulation and control board, spring, pull rod, and regulation and control board top is equipped with the rotor plate, and rotor plate normal running fit is equipped with h type connecting rod in the second support, and h type connecting rod bottom has and falls U type groove, and one side that the storehouse mouth was kept away from to the regulation and control board is equipped with the connecting block, and pull rod one end is passed through spring coupling in the connecting block, and the other end is equipped with the roller, and the pull rod middle section rotates locates and falls U type inslot, and the spring is in tensile state, and the roller is used for matching with the arc groove.
Further, the bin bottom is provided with a jacking post for jacking the pull rod so that the roller is in a lifting state, and when the object placing disc is placed in the bin opening and contacts with the jacking post, the jacking post falls down so that the roller is matched with the arc-shaped groove.
Further, the storage disc is provided with two rows of grooves, and the projection of the push-pull mechanism at the bottom of the bin is positioned between the two rows of grooves.
Further, the lifter plate includes two L templates, and hydraulic lifting rod bottom is equipped with the slider, and sliding fit is in the stopper from top to bottom, and the stopper sets up with the both sides wall opening that puts thing dish direction of movement looks vertically, and two L templates symmetrical connection are in the slider both sides, and a plurality of liquid taking pipe symmetrical distribution are on two L templates.
Further, the bottom of the L-shaped plate is provided with a plurality of caps, a liquid taking pipe is arranged in each cap in a penetrating mode, and the caps are used for covering corresponding detection reagent bottles.
Further, be equipped with the guide way on the regulation and control board, the guide way is towards storehouse mouth direction slope downward setting, and the stopper is equipped with the spacing groove towards a side wall of push-and-pull mechanism, and the stopper is run through at the spacing groove top, is equipped with the deflector on the slider, and deflector sliding fit is in the spacing groove, and the deflector other end is equipped with the guide post, and guide post sliding fit is in the guide way.
Further, the guide groove is divided into two sections, the included angle of the two sections of guide grooves is back to the direction of the bin opening, when the hydraulic lifting rod enables the sliding block to descend, the guide column firstly slides along the first section of guide groove, meanwhile, the regulating plate rotates back to the direction of the bin opening, and under the action of the pull rod, the object placing disc at the bin opening is pulled to a preset position for entering and exiting the reagent bin; when the guide post slides to the junction of the two sections of guide grooves, the second section of guide groove is in a vertical state; when the guide post continues to slide along the second section guide groove, the liquid taking pipe is promoted to be inserted into the corresponding detection reagent bottle.
A mass spectrometer comprising said mass spectrometer detection reagent access means.
The invention has the beneficial effects that: through ingenious cooperation of the lifting mechanism and the push-pull mechanism, automatic in-and-out of the detection reagent bottle in the reagent inlet and outlet bin and automatic insertion and extraction of the liquid taking pipe can be realized. When the hydraulic lifting rod descends the sliding block, the guide column slides along the first section of guide groove so that the pull rod pulls the storage disc from the bin opening into the preset position of reagent entering and exiting the bin; when the guide column slides to the junction of the two sections of guide grooves, the object placing disc just moves to a preset position of the reagent inlet and outlet bin, and the second section of guide groove is in a vertical state; the hydraulic lifting rod continuously descends the sliding block, and the guide column slides along the second section of guide groove so that the liquid taking pipe starts to be inserted into the corresponding detection reagent bottle.
Drawings
FIG. 1 is a view showing the external construction of a reagent inlet and outlet compartment according to an embodiment;
FIG. 2 is a diagram of a tray structure according to an embodiment;
FIG. 3 is a plan view of an embodiment of a tray placed at a mouth;
FIG. 4 is a diagram showing the structure of the tray according to the embodiment when the tray is placed at the bin opening;
FIG. 5 is an enlarged view of a portion of FIG. 4 at A;
FIG. 6 is a first block diagram of an elevator mechanism according to an embodiment;
FIG. 7 is a second block diagram of the lifting mechanism of the embodiment;
FIG. 8 is a plan view of a regulator board of an embodiment;
FIG. 9 is a diagram showing the structure of the tray after the tray moves to the reagent inlet and outlet;
reference numerals: the reagent feeding and discharging bin-1, a storage disc-2, a liquid taking tube-3, a bin gate-11, a groove-21, a hydraulic lifting rod-41, a lifting plate-42, a first bracket-411, a convex plate-22, an arc-shaped groove-23, a regulating plate-51, a spring-52, a pull rod-53, a rotating plate-511, a second bracket-512, an h-shaped connecting rod-513, a connecting block-515, a roller-531, a jacking column-12, an L-shaped plate-421, a sliding block-43, a limiting block-44, a cap-422, a guide groove-514, a limiting groove-441, a guide plate-45 and a guide column-451.
Detailed Description
As shown in fig. 3, the embodiment provides a device for detecting reagent in and out of a mass spectrometer, which comprises a reagent in and out bin 1, a storage tray 2, a plurality of liquid taking pipes 3, a lifting mechanism and a push-pull mechanism.
Specifically, as shown in fig. 1, a bin opening is formed in the bottom of one side of the reagent inlet and outlet bin 1, a bin door 11 capable of automatically opening and closing is arranged at the bin opening, the bottom of the bin door 11 is hinged to the reagent inlet and outlet bin 1, and when the bin door 11 is unfolded, the top surface of the bin door 11 is flush with the bottom of the reagent inlet and outlet bin 1.
Specifically, as shown in fig. 2, a plurality of grooves 21 are formed in the top of the storage tray 2, corresponding detection reagent bottles are placed in the grooves 21, the number and positions of the detection reagent bottles are set according to practical situations, 2 rows of 3 columns of grooves 21 are arranged in the storage tray 2 in this embodiment, and the width of the storage tray 2 is consistent with the width of the bin opening, so that the storage tray 2 can be placed at the bin opening.
Specifically, the push-pull mechanism is arranged in the reagent feeding and discharging bin 1, the projection of the push-pull mechanism at the bottom of the bin is positioned between two rows of grooves 21 of the storage tray 2, the push-pull mechanism is used for pulling the storage tray 2 at the bin opening to a preset position in the reagent feeding and discharging bin 1, and when a new detection reagent bottle needs to be replaced, the push-pull mechanism is also used for pushing the storage tray 2 from the reagent feeding and discharging bin 1 to the bin opening.
One implementation mode of the push-pull mechanism is as follows: as shown in fig. 3 and 4, the device comprises a regulating plate 51, a spring 52 and a pull rod 53, wherein the top of the regulating plate 51 is provided with a rotating plate 511, the rotating plate 511 is in running fit with a second bracket 512, a power source for rotating the regulating plate 51 can be a motor, an h-shaped connecting rod 513 is arranged at one side of the bottom of the regulating plate 51, which is far away from a bin opening, an inverted U-shaped groove is formed in the bottom of the h-shaped connecting rod 513, a connecting block 515 is arranged at one side of the regulating plate 51, which is far away from the bin opening, one end of the pull rod 53 is connected with the connecting block 515 through the spring 52, the middle section of the pull rod 53 is rotationally arranged in the inverted U-shaped groove, a roller 531 is arranged at the other end of the pull rod 53, and the spring 52 is always in a stretching state, so that the roller 531 is guaranteed to be propped against the bin bottom of a reagent inlet and outlet bin 1.
One end of the storage tray 2 facing the bin opening is provided with a convex plate 22, the bottom of the convex plate 22 is flush with the bottom of the storage tray 2, and the top of the convex plate 22 is provided with an arc groove 23. When the storage tray 2 is placed at the preset position of the bin opening, the roller 531 can be matched with the arc-shaped groove 23, and at the moment, the roller 531 always abuts against the inside of the arc-shaped groove 23 under the action of the tensile force of the spring 52.
There are two ways to achieve the matching of the roller 531 with the arc groove 23, the first: the staff inserts the convex plate 22 of the object placing disc 2 from the bin mouth forcefully and slowly, the roller 531 is extruded and lifted, and when clicking sounds, the roller 531 falls into the arc-shaped groove 23; the first mode is laborious and requires a good speed control, and the second mode is more optimal, and is specifically as follows: as shown in fig. 5, the position of the bin bottom close to the bin opening is provided with a jack-up post 12, the jack-up post 12 can be lifted up when needed, and can be completely hidden inside the bin bottom when not needed, when in use, a worker firstly turns on a control switch of the jack-up post 12 to lift up the pull rod 53, so that the roller 531 is in a lifted state, then the object placing tray 2 is placed into the bin opening and contacted with the jack-up post 12, and then the jack-up post 12 is dropped to the original position, so that the roller 531 is dropped into the arc groove 23.
When in use, a new detection reagent bottle is placed at the corresponding position of the object placing disc 2; opening the bin gate 11 and lifting the jack-up column 12; placing the object placing disc 2 into the bin opening and contacting the jack-up post 12, and enabling the jack-up post 12 to fall to the original position, so that the matching of the roller 531 and the arc-shaped groove 23 is completed; the regulating plate 51 rotates in a direction away from the bin opening under the action of the power source, and in the process, one end of the pull rod 53 connected with the spring 52 is always subjected to the tensile force of the spring 52, so that the roller 531 always abuts against the arc-shaped groove 23 and pulls the storage tray 2 to a preset position in the reagent feeding and discharging bin 1; on the contrary, when the batch of detection reagent bottles are used up, the regulating plate 51 rotates towards the direction of the bin opening under the action of the power source.
Specifically, the lifting mechanism is arranged in the reagent inlet and outlet bin 1 and comprises a hydraulic lifting rod 41 and a lifting plate 42, the top of the hydraulic lifting rod 41 is arranged on the first bracket 411, and the bottom of the hydraulic lifting rod is connected with the lifting plate 42,6 liquid taking pipes 3 which are distributed on the lifting plate 42 and used for being inserted into corresponding detection reagent bottles downwards.
More specifically, as shown in fig. 6 and 7, the lifting plate 42 includes two L-shaped plates 421, a slider 43 is disposed at the bottom of the hydraulic lifting rod 41, the slider 43 is slidably fitted in the stopper 44 up and down, two side walls of the stopper 44 perpendicular to the moving direction of the tray 2 are opened, the two L-shaped plates 421 are symmetrically connected to two sides of the slider 43, and 6 liquid taking tubes 3 are symmetrically distributed on the two L-shaped plates 421. When in use, after the storage tray 2 is pulled to a preset position in the reagent inlet and outlet bin 1, the hydraulic lifting rod 41 enables the sliding block 43 and the lifting plate 42 to descend, so that the liquid taking pipe 3 is inserted into a corresponding detection reagent bottle.
More specifically, in order to protect the detection reagent bottles, 6 caps 422 are disposed at the bottom of the L-shaped plate 421, a liquid taking tube 3 is inserted into each cap 422, and the caps 422 are used for covering the corresponding detection reagent bottles.
The power source of the adjusting plate 51 may be a motor, preferably, the adjusting plate 51 may also share a power source with the lifting plate 42, in a specific manner: as shown in fig. 8, the regulating plate 51 is provided with a guide groove 514, the guide groove 514 is inclined downward toward the direction of the bin opening, a limit groove 441 is provided on a side wall of the limit block 44 toward the push-pull mechanism, the top of the limit groove 441 penetrates the limit block 44, the slide block 43 is provided with a guide plate 45, the guide plate 45 is slidably engaged with the limit groove 441, the other end of the guide plate 45 is provided with a guide column 451, and the guide column 451 is slidably engaged with the guide groove 514. When the slider 43 is lowered by the hydraulic lifting lever 41, the guide bar 451 is caused to slide along the guide groove 514, and the regulation plate 51 is rotated.
More specifically, the guide groove 514 is divided into two sections, the included angle of the two sections of guide grooves 514 is opposite to the direction of the bin opening, when the hydraulic lifting rod 41 makes the sliding block 43 descend, the guide column 451 firstly slides along the first section of guide groove 514, meanwhile, the regulating plate 51 rotates towards the direction opposite to the bin opening, the pull rod 53 moves towards the deep part of the bin opening, the object placing tray 2 at the bin opening is pulled to the preset position of the reagent inlet and outlet bin 1 under the action of the pull rod 53, and in the process, the lifting plate 42 and the liquid taking tube 3 thereon can descend for a certain distance, but the tail end of the liquid taking tube 3 is still higher than the detection reagent bottle; when the hydraulic lifting rod 41 continues to lower the sliding block 43, the guide column 451 slides to the junction of the two sections of guide grooves 514, the tray 2 just moves to the preset position of the reagent inlet and outlet bin 1, and the second section of guide groove 514 is in a vertical state at this time, which means that the control plate 51 will not rotate when the guide column 451 slides down along the second section of guide groove 514; when the slider 43 is further lowered by the hydraulic lifting lever 41, the guide column 451 slides along the second-stage guide groove 514, and the liquid taking tube 3 is urged to be inserted into the corresponding test reagent bottle, as shown in fig. 9.
When a new detection reagent bottle needs to be replaced, the hydraulic lifting rod 41 enables the sliding block 43 to be lifted, the guide column 451 firstly slides along the second section of guide groove 514, so that the regulating plate 51 does not rotate, and only the lifting plate 42 moves upwards in the process, so that the liquid taking tube 3 is pulled out of the detection reagent bottle; when the guide column 451 slides to the junction of the two sections of guide grooves 514, the liquid taking tube 3 is completely separated from the detection reagent bottle; the hydraulic lifting rod 41 continues to lift the sliding block 43, and the guide column 451 slides along the first-stage guide groove 514 to enable the pull rod 53 to push the object placing tray 2 from the reagent inlet and outlet bin 1 to the bin opening; the jack-up column 12 is raised so that the staff takes the tray 2 away.
In another embodiment, a mass spectrometer comprises a mass spectrometer detection reagent access device as described above.
In conclusion, through ingenious cooperation of the lifting mechanism and the push-pull mechanism, automatic in-and-out of the detection reagent bottle in the reagent in-and-out bin 1 and automatic insertion and extraction of the liquid taking pipe 3 can be realized.
The above embodiments are merely for illustrating the technical ideas and features of the present invention, and are not meant to be exclusive or limiting. It will be understood by those skilled in the art that various changes may be made and equivalents may be substituted for elements thereof without departing from the scope of the invention.

Claims (8)

1. The device for detecting the reagent inlet and outlet of the mass spectrometer is characterized by comprising a reagent inlet and outlet bin (1), a storage disc (2), a plurality of liquid taking pipes (3), a lifting mechanism and a push-pull mechanism;
one side of the reagent inlet and outlet bin (1) is provided with a bin opening, a bin gate (11) is arranged at the bin opening, the bottom of the bin gate (11) is hinged to the reagent inlet and outlet bin (1), and when the bin gate (11) is unfolded, the top surface of the bin gate is flush with the bin bottom of the reagent inlet and outlet bin (1);
the top of the storage tray (2) is provided with a plurality of grooves (21), the grooves (21) are used for accommodating corresponding detection reagent bottles, and the width of the storage tray (2) is consistent with the width of the bin opening;
the push-pull mechanism is arranged in the reagent inlet and outlet bin (1) and used for enabling the storage tray (2) to move between the bin opening and the reagent inlet and outlet bin (1), a convex plate (22) is arranged at one end, facing the bin opening, of the storage tray (2), the bottom of the convex plate (22) is flush with the bottom of the storage tray (2), an arc-shaped groove (23) is formed in the top of the convex plate (22), the push-pull mechanism comprises a regulating plate (51), a spring (52) and a pull rod (53), a rotating plate (511) is arranged at the top of the regulating plate (51), the rotating plate (511) is in rotating fit with a second bracket (512), an h-shaped connecting rod (513) is arranged at the bottom of the regulating plate (51), an inverted U-shaped groove is formed in the bottom of the h-shaped connecting rod (513), a connecting block (515) is arranged at one side, far away from the bin opening, one end of the pull rod (53) is connected with the connecting block (515) through the spring (52), a roller (531) is arranged at the other end, the middle section of the pull rod (53) is rotationally arranged in the inverted U-shaped groove, the spring (52) is in a stretching state, and the roller (531) is used for being matched with the arc-shaped groove (23);
the lifting mechanism is arranged in the reagent inlet and outlet bin (1) and comprises a hydraulic lifting rod (41) and a lifting plate (42), the top of the hydraulic lifting rod (41) is arranged on the first bracket (411), the bottom of the hydraulic lifting rod is connected with the lifting plate (42), and a plurality of liquid taking pipes (3) are distributed on the lifting plate (42) and are used for being inserted into corresponding detection reagent bottles.
2. The mass spectrometer detection reagent access device according to claim 1, wherein the bottom of the bin is provided with a jack-up post (12) for jack-up of the pull rod (53) to bring the roller (531) into a lifted state, and when the tray (2) is placed in the bin mouth and contacts the jack-up post (12), the jack-up post (12) falls down to match the roller (531) with the arc-shaped groove (23).
3. The mass spectrometer detection reagent access device according to claim 1, wherein the tray (2) is provided with two rows of grooves (21), and the projection of the push-pull mechanism on the bottom of the bin is located between the two rows of grooves (21).
4. The mass spectrometer detection reagent inlet and outlet device according to claim 3, wherein the lifting plate (42) comprises two L-shaped plates (421), a sliding block (43) is arranged at the bottom of the hydraulic lifting rod (41), the sliding block (43) is matched in the limiting block (44) in an up-down sliding manner, openings on two side walls of the limiting block (44) perpendicular to the moving direction of the object placing plate (2) are formed, the two L-shaped plates (421) are symmetrically connected to two sides of the sliding block (43), and the liquid taking pipes (3) are symmetrically distributed on the two L-shaped plates (421).
5. The device for detecting reagent in and out of a mass spectrometer according to claim 4, wherein a plurality of caps (422) are arranged at the bottom of the L-shaped plate (421), a liquid taking pipe (3) is arranged in each cap (422) in a penetrating way, and the caps (422) are used for covering corresponding detection reagent bottles.
6. The mass spectrometer detection reagent inlet and outlet device according to claim 4, wherein a guide groove (514) is formed in the regulating plate (51), the guide groove (514) is obliquely arranged downwards towards the direction of the bin opening, a limit groove (441) is formed in one side wall of the limit block (44) towards the push-pull mechanism, the top of the limit groove (441) penetrates through the limit block (44), a guide plate (45) is arranged on the sliding block (43), the guide plate (45) is in sliding fit with the limit groove (441), a guide column (451) is arranged at the other end of the guide plate (45), and the guide column (451) is in sliding fit with the guide groove (514).
7. The mass spectrometer detection reagent inlet and outlet device according to claim 6, wherein the guide groove (514) is divided into two sections, the included angle of the two sections of guide grooves (514) is opposite to the direction of the bin mouth, when the hydraulic lifting rod (41) enables the sliding block (43) to descend, the guide column (451) slides along the first section of guide groove (514) at first, meanwhile, the regulating plate (51) rotates towards the direction opposite to the bin mouth, and the object placing disc (2) at the bin mouth is pulled to the preset position of the reagent inlet and outlet bin (1) under the action of the pull rod (53); when the guide column (451) slides to the junction of the two sections of guide grooves (514), the second section of guide groove (514) is in a vertical state; when the guide column (451) slides along the second-stage guide groove (514), the liquid taking pipe (3) is caused to be inserted into the corresponding detection reagent bottle.
8. A mass spectrometer comprising a mass spectrometer detection reagent access device as claimed in any one of claims 1 to 7.
CN202310460547.9A 2023-04-26 2023-04-26 Mass spectrometer detection reagent business turn over device and mass spectrometer Active CN116190195B (en)

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