CN1161092C - Cosmetics - Google Patents
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- CN1161092C CN1161092C CNB001069233A CN00106923A CN1161092C CN 1161092 C CN1161092 C CN 1161092C CN B001069233 A CNB001069233 A CN B001069233A CN 00106923 A CN00106923 A CN 00106923A CN 1161092 C CN1161092 C CN 1161092C
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Abstract
A cosmetic is disclosed, includeing (A) an extract of camomile and (B) one or more kinds of plant extracts selected from dog rose fruits and brunet (Sanguisorba officinalis).
Description
Technical field
The present invention relates to the good cosmetics of whitening effect.
Background technology
The speckle of skin or freckle generally can be described as owing to expose stimulation, hormonal imbalance or the inherited genetic factors that causes under daylight, make the melanocyte activation, and the result is produced by the synthetic melanin of melanocyte abnormal deposition in skin.
In order to prevent the generation of this speckle or freckle, previously used is to contain the skin-lightening cosmetic material that L-ascorbic acid and derivant, hydroquinone derivative, kojic acid and derivant, intacellin etc. can suppress the synthetic composition of melanin.But, because all only demonstrating faint melanin, these materials suppress effect, join the occasion in the cosmetic material respectively separately, can not obtain sufficient whitening effect.
Therefore, attempting with these materials and the combination of various plant extract, to strengthen whitening effect.For example, kojic acid and derivant thereof and Chamomile (Chamomile), the combination (spy opens flat 3-236322 communique) of Radix Arnebiae (Radix Lithospermi) plant extracts such as (Lithospermum Root), hydroquinone glucoside and mulberry (Mulberry Bark), the combination (spy opens flat 5-139950 communique) of Aloe extracts from crude drugs such as (Aloe), kojic acid and derivant thereof and Echinacea (Echinacea), the combination (spy opens flat 7-17846 communique) of Herba lamii barbati plant extracts such as (White Nettle), kojic acid and derivant thereof and acerola (Barbados's Fructus Pruni pseudocerasi) are (Acerola), the combination of Semen Ginkgo plant extracts such as (Ginkgo) (spy opens flat 7-61915 communique) etc.But even these combinations, the reinforced effects of whitening is also insufficient, can not be satisfactory.
Therefore, the object of the present invention is to provide the good cosmetics of a kind of whitening effect.
Summary of the invention
If the inventor finds chamomile extract and the plant extract that extracts from Fructus Rosae or Radix Sanguisorbae are used in combination, can be prevented pigmentation, have the skin-lightening cosmetic material of good whitening effect.
Composition used in the present invention (A) chamomile extract can pass through hydrophilic organic solvents such as water, ethanol, propanol, propylene glycol, 1,3 butylene glycol; Vegetable oil organic solvents such as Oleum Ricini, peach kernel oil (PersicOil), soybean oil, Oleum helianthi, isopropyl myristate, two capric acid DOPCP, liquid paraffin, squalane; Or the flower of their mixture extraction feverfew Chamomile (Matticaria chamomilla L. (Compositae)) obtains.In the present invention, can use the chamomile extract that obtains like this more than a kind.Wherein, because the oil-soluble chamomile extract has good whitening effect thereby preferred, the extract that especially preferably uses squalane to obtain.
Generally contain chamazulene (Chamazulene), umbelliferone (Umbelliferone), ayapanin, matricin (Matricin), matricarin (Matricarin), taraxasterol (Taraxasterol), lupeol (1upeol), apiin (Apiin), volution ether compound etc. in the described chamomile extract.Specifically, for example open the volution ether compound of flat 7-206657 communique record as effective ingredient with the spy.
The preferred content of composition (A) is 0.00001~5 weight % as solid constituent in the cosmetics total amount, if particularly contain 0.0005~3 weight %, more preferably 0.001~2 weight % can obtain sufficient whitening effect, and the storage stability of goods is good.
In composition used in the present invention (B) plant extract, rose hip extract (Rose FruitExtract) can be extracted by the fruit of the Flos rosae multiflorae in the Rosaceae (Rosa multiflora Thunberg) or its sibling species and obtain.
In addition, Radix Sangusorbae extract (Burnet Extract) can be obtained by the root or the rhizome extraction of rosaceous Radix Sanguisorbae (Sanguisorba 0fficinalis Linne) or its mutation.
Consider from the aspect of whitening effect and storage stability, in cosmetics of the present invention, the content of its composition (B) plant extract is 0.00001~5 weight % as solid constituent in the cosmetic material total amount, preferred especially 0.0005~3 weight %, more preferably 0.001~2 weight %.
If further adding chromone derivative shown in the following general formula (1) in cosmetics of the present invention again can strengthen whitening effect, thereby be preferred as composition (C).
(in the formula, R
1The straight or branched alkyl of expression carbon 1~16, R
2The alkoxyl of expression hydrogen atom, hydroxyl or carbon 1~6.〕
Preferred especially R in the chemical compound of general formula (1) expression
1Be the straight or branched alkyl of carbon 4~9, R
2Material for hydrogen atom, hydroxyl or methoxyl group.These chemical compounds can use more than a kind.
When using composition (C), its content preferably is 0.01~20 weight %, particularly 0.1~10 weight % in the cosmetics total amount, and more preferably 0.1~5 weight % can strengthen whitening effect, and usability is good, thereby is preferred.
If add again in the cosmetics of the present invention be selected from UV absorbent and the ultraviolet scattering diluent more than a kind, can suppress the melanin that Exposure to Sunlight causes and generate, thereby be preferred.There is no particular limitation for described UV absorbent and ultraviolet scattering diluent, and common employed oil-soluble or water solublity UV absorbent, ultraviolet scattering diluent all can use.
Wherein, preferred octyldimethyl para-amino benzoic acid, 2-ethylhexyl p-methoxycinnamate ester, 4-methoxyl group-4 '-tert-butyl group dibenzoyl methane, 1-(3, the 4-Dimethoxyphenyl)-4,4-dimethyl-1,3-pentanedione, 2-hydroxyl-UV absorbent such as 4-methoxy benzophenone; Ultraviolet scattering diluents such as zinc oxide, titanium oxide, ferrum oxide.When using these compositions, its content preferably is 0.001~30 weight % in the cosmetic material total amount, preferred especially 0.01~30 weight %, more preferably 0.05~20 weight %.
In cosmetics of the present invention, except that mentioned component, can suitably add employed various any compositions such as goods beyond the common cosmetics, medicine, medicine in case of necessity.For example water, ethanol, oiliness composition, wetting agent, viscosifier, antiseptic, emulsifying agent, active ingredient, powder body, coloring agent, spice, emulsion stabilizer, pH regulator agent etc.
Cosmetics of the present invention can prepare according to conventional method.In addition, cosmetics of the present invention not only are defined in general cosmetics for skin, also comprise goods beyond the medicine, external used medicine etc., and its dosage form also can be selected arbitrarily according to purpose.That is to say, can be dosage forms such as cream cream, ointment, emulsion, solution, gel, or form such as facial film, lotion, powder, patch.
Because cosmetics of the present invention can prevent pigmentation, have good whitening effect, therefore can be used as and prevent that the cosmetics that produce speckle or freckle because of Exposure to Sunlight etc. from using.
The specific embodiment
Embodiment 1~4 and comparative example 1~5
Preparation has the cream cream of forming shown in the table 2, estimates its whitening effect.The result is as shown in table 2.
(preparation method)
Oil-phase component in the table 2 is mixed, and 80 ℃ of following heating for dissolving, to the water-phase component that wherein is heated to 60 ℃, cool to room temperature under stirring condition obtains the cream cream again in the time of stirring.
(inducing the whitening effect test of the pigmented spots of generation for UV-B)
In 20 subjects' upper arm inboard, with 2 times of ultraviolet of measuring the radiation of UV-B fields of minimal erythema dose, 1 order 1 time shone 2, induced the chromogenesis speckle, and continuously coating sample on these pigmented spots (2 times on the 1st, applied 1 month) is investigated its whitening effect.
Adopt colour difference meter (color technical research institute system CMS-1200 in the village) to carry out colorimetric, calculate L by the マ Application ヤ Le value that obtains
*Value is with the Δ Δ L that represents its recovery
*Value is estimated.
Δ Δ L
*Value defines with following formula.That is to say the L at the tested position before the beginning coated coupons and the tested position of non-coated coupons
*Value is remembered respectively and is made L
0, L
0', the L* value at continuously coating each position after 1 month is remembered respectively and is made L
1, L
1', the numerical value that calculates according to following formula is Δ Δ L
*Value.
Δ Δ L
*Value=(L
1-L
0)-(L '
1-L
0')
The result obtains subject's pairing scoring of Δ Δ L* value separately according to boundary shown in the table 1, and 20 meansigma methods is as shown in table 2.
Scoring | Criterion is represented the Δ Δ L that pigmented spots are recovered after 1 month *Value satisfies following formula |
5 | 1.0≤ΔΔL * |
4 | 0.5 ≤ΔΔL *<1.0 |
3 | 0.2≤ΔΔL *<0.5 |
2 | -0.2≤ΔΔL *<0.2 |
1 | ΔΔL *<-0.2 |
Table 2
Composition (weight %) | Embodiment | Comparative example | ||||||||
1 | 2 | 3 | 4 | 1 | 2 | 3 | 4 | 5 | ||
Oil phase | Glyceryl monostearate | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 |
The monostearate macrogol ester | 2.0 | 2.0 | 2.0 | 2.0 | 2.0 | 2.0 | 2.0 | 2.0 | 2.0 | |
Squalane | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | |
Tricaprylin | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | 8.0 | |
Stearyl alcohol | 5.5 | 5.5 | 5.5 | 5.5 | 5.5 | 5.5 | 5.5 | 5.5 | 5.5 | |
Dimethyl polysiloxane | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | |
Propylene glycol | 5.0 | 5.0 | 5.0 | 5.0 | 6.0 | 6.0 | 5.0 | 5.0 | 5.0 | |
2-(1-ethyl pentyl group)-7-methoxyl group chromone *4 | - | - | 3.0 | 3.0 | - | - | - | 3.0 | - | |
2-ethylhexyl p-methoxycinnamate ester | - | - | - | 3.0 | - | - | - | - | - | |
Particulate titanium dioxide | - | - | - | 0.5 | - | - | - | - | - | |
Spice | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | |
Water | (A) Chamomile extracting solution *1 | 0.5 | 0.5 | 0.5 | 0.5 | 1.0 | - | - | - | - |
(B) Fructus Rosae extracting solution *2 | 0.5 | - | 0.5 | 0.5 | - | 1.0 | - | - | - | |
(B) Radix Sanguisorbae extracting solution *3 | - | 0.5 | 0.5 | 0.5 | - | - | 1.0 | - | - | |
Chinese holly rubber acid sodium | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
Second one amine tetraacethyl one sodium | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | |
Antiseptic | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | |
Ion exchange water | Surplus | Surplus | Surplus | Surplus | Surplus | Surplus | Surplus | Surplus | Surplus | |
Whitening effect (average score) | 3.9 | 4.0 | 4.4 | 4.5 | 2.5 | 2.2 | 2.3 | 1.7 | 1.6 |
*1: Chamomile extracting solution (squalane extract)
*2: Fructus Rosae extracting solution (Maruzen Pharmaceuticals Co., Ltd.'s system, ethanol extraction)
*3: Radix Sanguisorbae extracting solution (Maruzen Pharmaceuticals Co., Ltd.'s system, ethanol extraction)
*4: the synthesis example of opening in the flat 7-188208 communique according to the spy 2 prepares
As can be known from the results of Table 2: cream cream of the present invention is owing to contain composition (A) and (B), whitening effect is significantly improved.
Claims (6)
1, cosmetics contain (A) oil-soluble chamomile extract, and (B) are selected from the plant extract more than a kind in Fructus Rosae and the Radix Sangusorbae extract.
2, cosmetics as claimed in claim 1, also contain composition (C): chromone derivative shown in the following general formula (1),
In the formula, R
1The straight or branched alkyl of expression carbon 1~16, R
2The alkoxyl of expression hydrogen atom, hydroxyl or carbon 1~6.
3, cosmetics as claimed in claim 1 or 2, wherein composition (A) is for extracting the chamomile extract that obtains with squalane.
4, cosmetics as claimed in claim 1 or 2, in the cosmetics total amount, composition (A) is 0.0005~3 weight % as solid constituent.
5, cosmetics as claimed in claim 1 or 2, in the cosmetics total amount, composition (B) is 0.0005~3 weight % as solid constituent.
6, cosmetics as claimed in claim 2, in the cosmetics total amount, composition (C) is 0.1~10 weight % as solid constituent.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP112972/1999 | 1999-04-21 | ||
JP11112972A JP2000302661A (en) | 1999-04-21 | 1999-04-21 | Cosmetic |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1272360A CN1272360A (en) | 2000-11-08 |
CN1161092C true CN1161092C (en) | 2004-08-11 |
Family
ID=14600180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB001069233A Expired - Fee Related CN1161092C (en) | 1999-04-21 | 2000-04-21 | Cosmetics |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP2000302661A (en) |
CN (1) | CN1161092C (en) |
TW (1) | TWI253937B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20040043971A (en) * | 2002-11-20 | 2004-05-27 | 동방에프티엘 주식회사 | Extract compositions comprising a natural phellinus linteus, green tea, caryophilli flos and rosae fructus and cosmetic products comprising their extracts |
US20090317341A1 (en) | 2008-06-18 | 2009-12-24 | Conopco, Inc., D/B/A Unilever | Compositions for Lightening Skin Color |
JP2015117221A (en) * | 2013-12-20 | 2015-06-25 | 一丸ファルコス株式会社 | Stem cell activation agent |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2957334B2 (en) * | 1991-11-26 | 1999-10-04 | ポーラ化成工業株式会社 | Cosmetics |
JP3071990B2 (en) * | 1993-12-27 | 2000-07-31 | 花王株式会社 | External preparation for skin |
JP3696271B2 (en) * | 1994-09-22 | 2005-09-14 | 花王株式会社 | Whitening cosmetics |
JP3499616B2 (en) * | 1994-10-20 | 2004-02-23 | 一丸ファルコス株式会社 | Application to hydroxytyrosol, melanin production inhibitor or lipid peroxide production inhibitor |
JPH10265321A (en) * | 1997-03-19 | 1998-10-06 | Shiseido Co Ltd | Skin preparation for external use |
JP3592918B2 (en) * | 1997-05-14 | 2004-11-24 | 花王株式会社 | Cosmetics |
-
1999
- 1999-04-21 JP JP11112972A patent/JP2000302661A/en active Pending
-
2000
- 2000-03-22 TW TW89105229A patent/TWI253937B/en not_active IP Right Cessation
- 2000-04-21 CN CNB001069233A patent/CN1161092C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
TWI253937B (en) | 2006-05-01 |
JP2000302661A (en) | 2000-10-31 |
CN1272360A (en) | 2000-11-08 |
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Granted publication date: 20040811 Termination date: 20190421 |