CN115996944A - 来自frzb蛋白的“netrin样”结构域的肽的治疗潜力 - Google Patents

来自frzb蛋白的“netrin样”结构域的肽的治疗潜力 Download PDF

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Publication number
CN115996944A
CN115996944A CN202180035631.5A CN202180035631A CN115996944A CN 115996944 A CN115996944 A CN 115996944A CN 202180035631 A CN202180035631 A CN 202180035631A CN 115996944 A CN115996944 A CN 115996944A
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CN
China
Prior art keywords
pep16
peptide
cells
cartilage
pathway
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Pending
Application number
CN202180035631.5A
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English (en)
Chinese (zh)
Inventor
弗里德里克·凯洛托
马里恩·克劳德尔
克里斯托夫·查尔伦
让-伊夫斯·朱泽奥
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Nanxi University Medical Center
Centre National de la Recherche Scientifique CNRS
Institut National Polytechnique de Lorraine
Original Assignee
Nanxi University Medical Center
Centre National de la Recherche Scientifique CNRS
Institut National Polytechnique de Lorraine
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Publication date
Application filed by Nanxi University Medical Center, Centre National de la Recherche Scientifique CNRS, Institut National Polytechnique de Lorraine filed Critical Nanxi University Medical Center
Publication of CN115996944A publication Critical patent/CN115996944A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN202180035631.5A 2020-05-18 2021-05-18 来自frzb蛋白的“netrin样”结构域的肽的治疗潜力 Pending CN115996944A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20315243.4 2020-05-18
EP20315243.4A EP3912991A1 (en) 2020-05-18 2020-05-18 Therapeutic potential of peptides from the "netrin-like" domain of the frzb protein
PCT/EP2021/063109 WO2021233896A1 (en) 2020-05-18 2021-05-18 Therapeutic potential of peptides from the "netrin-like" domain of the frzb protein

Publications (1)

Publication Number Publication Date
CN115996944A true CN115996944A (zh) 2023-04-21

Family

ID=71607831

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180035631.5A Pending CN115996944A (zh) 2020-05-18 2021-05-18 来自frzb蛋白的“netrin样”结构域的肽的治疗潜力

Country Status (6)

Country Link
US (1) US20230183303A1 (https=)
EP (2) EP3912991A1 (https=)
JP (1) JP2023541087A (https=)
CN (1) CN115996944A (https=)
CA (1) CA3178537A1 (https=)
WO (1) WO2021233896A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202401058D0 (en) * 2024-01-26 2024-03-13 Univ London Queen Mary Treatment

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1826130A (zh) * 2003-07-18 2006-08-30 塞诺菲-安万特德国有限公司 Pak抑制物用于治疗关节疾病的用途
JP5967685B1 (ja) * 2016-01-13 2016-08-10 国立大学法人名古屋大学 軟骨細胞のＷｎｔ／β−カテニンシグナル伝達経路の活性化抑制組成物及び変形性関節症治療用医薬組成物
CN106573030A (zh) * 2014-05-16 2017-04-19 因特穆内公司 Lpa相关蛋白和rna表达

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040031072A1 (en) * 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
WO2005070448A2 (en) * 2004-01-21 2005-08-04 Five Prime Therapeutics, Inc. Methods of use for secreted frizzled-related protein 3 (sfrp-3) in the prevention and treatment of disease
FR3051192B1 (fr) 2016-05-13 2020-12-25 Univ De Lorraine Methode de purification de proteines recombinantes par affinite basee sur l'activite lectinique du domaine crd d'une galectine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1826130A (zh) * 2003-07-18 2006-08-30 塞诺菲-安万特德国有限公司 Pak抑制物用于治疗关节疾病的用途
CN106573030A (zh) * 2014-05-16 2017-04-19 因特穆内公司 Lpa相关蛋白和rna表达
JP5967685B1 (ja) * 2016-01-13 2016-08-10 国立大学法人名古屋大学 軟骨細胞のＷｎｔ／β−カテニンシグナル伝達経路の活性化抑制組成物及び変形性関節症治療用医薬組成物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SARAH THYSEN等: "Osteogenesis induced by frizzled-related protein (FRZB) is linked to the netrin-like domain", LAB INVEST ., vol. 96, no. 5, 29 February 2016 (2016-02-29) *

Also Published As

Publication number Publication date
CA3178537A1 (en) 2021-11-25
US20230183303A1 (en) 2023-06-15
EP4153611A1 (en) 2023-03-29
EP3912991A1 (en) 2021-11-24
WO2021233896A1 (en) 2021-11-25
JP2023541087A (ja) 2023-09-28

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