CN1159940A - Composition for promoting muscle growing and skin healing and preparing method thereof - Google Patents
Composition for promoting muscle growing and skin healing and preparing method thereof Download PDFInfo
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- CN1159940A CN1159940A CN 97100165 CN97100165A CN1159940A CN 1159940 A CN1159940 A CN 1159940A CN 97100165 CN97100165 CN 97100165 CN 97100165 A CN97100165 A CN 97100165A CN 1159940 A CN1159940 A CN 1159940A
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- radix angelicae
- semen armeniacae
- armeniacae amarum
- myrrha
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Abstract
A medicinal composition for treating intractable chronic ulcer, large-area nutritional skin ulcer and deep ulcer such as fistula is prepared from 6 Chinese-medicinal materials such as bitter apricot kernel, liquorice root, Chinese angelica root, dahurian angelica root, frankincense, etc. and pharmacological acceptable carrier, and features distinct curative effect and no hypertoxic components, for example Pb, Hg and Zn.
Description
The present invention relates to a kind of composition for promoting muscle growing and skin healing with heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling and reducing swelling and alleviating pain effect and preparation method thereof, specifically, is a kind of Chinese medicine pharmaceutical composition of external.
At present, many medicines that the difficult more property of treatment clinically chronic ulcer is used comprise that Western medicine and Chinese medicine can not reach ideal curative effect, usually bring the misery of skin-grafting amputation to patient.
The present invention just provides a kind of like this Chinese medicine composition of growing muscle and healing skin, it has unique promoting healing effect to healing property of difficulty chronic ulcer, especially evident in efficacy to deep ulcer such as large tracts of land dystrophic skin ulcer and sinus tract, fistulas, and do not contain any severe toxicity (lead, hydrargyrum, zinc etc.) composition.
The present invention also provides the preparation method of this Chinese medicine composition simultaneously.
Growing muscle and healing skin Chinese medicine composition of the present invention can be made active component by the Chinese crude drug of following proportioning: (by weight) Semen Armeniacae Amarum 10-70 part, Radix Glycyrrhizae 1-20 part, Radix Angelicae Sinensis 1-20 part, Radix Angelicae Dahuricae 1-20 part, Olibanum 1-10 part, Myrrha 1-10 part; Wherein be preferably: (by weight) Semen Armeniacae Amarum 15-45 part, Radix Glycyrrhizae 1-10 part, Radix Angelicae Sinensis 1-10 part, Radix Angelicae Dahuricae 1-10 part, Olibanum 1-5 part, Myrrha 1-5 part; Wherein the best is: (by weight)
Semen Armeniacae Amarum 20-30 part, Radix Glycyrrhizae 4-8 part, Radix Angelicae Sinensis 4-8 part,
Radix Angelicae Dahuricae 4-8 part, Olibanum 1-2 part, Myrrha 1-2 part.Wherein preferably Semen Armeniacae Amarum is carried out following processing: will concoct container and be preheated to 100-200 ℃, and drop into Semen Armeniacae Amarum and fried 2-3 minute, and reach 80-95 ℃ to the Semen Armeniacae Amarum surface temperature, and add 90-100 ℃ hot water of 2 times of amounts, and acutely boil taking-ups in 2-8 minute, and peel.
Active component in composition for promoting muscle growing and skin healing of the present invention can adopt conventional Chinese medicinal preparation method to make as pulverizing and/or extracting.Can and grind above-mentioned Chinese crude drug pulverize separately and be powder, mixing; Also above-mentioned Chinese crude drug ethanol extract be can be made with alcohol extraction, vegetable oil such as Oleum Sesami or sesame oil extraction perhaps used; Preferably the Chinese crude drug ethanol extraction of said ratio, concentration of ethanol is 50-95%, more preferably 80% ethanol; Percolation that extracting method is carried for conventional Chinese crude drug extracting method warm macerating as usual and reflux extraction etc. have description in the 65-72 page or leaf in Cao Chunlin chief editor " pharmaceutics of Chinese drugs ".Most preferably, in 50-80 ℃ following the Radix Angelicae Dahuricae of pulverizing, Radix Angelicae Sinensis and Radix Glycyrrhizae with twice of the alcohol reflux of 50-95%, the extracted twice time was respectively 2-4 hour and 1-3 hour, last spissated thick paste relative density is 1.30-1.35 (50 ℃ record), Semen Armeniacae Amarum, Olibanum and Myrrha are crushed into powder, again with the two mixing.
Composition for promoting muscle growing and skin healing of the present invention can also contain pharmaceutically acceptable carrier for example additives such as antiseptic, excipient etc., adopts conventional method to make exterior-applied emulsion, ointment, paste, liniment, plaster, aerosol etc.Referring to 325-351 in Cao Chunlin chief editor " pharmaceutics of Chinese drugs "; The 454-463 page or leaf.
Pharmaceutical composition of the present invention has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling and reducing swelling and alleviating pain effect, healing property of difficulty chronic ulcer had unique promoting healing effect, especially evident in efficacy to deep ulcer such as large tracts of land dystrophic skin ulcer and sinus tract, fistulas, and do not contain any severe toxicity (lead, hydrargyrum, zinc etc.) composition.Can obviously shorten the healing time of animal skin ulcer thing through the experimental study said composition, shorten and take off the abdominal mass time, improve healing rate.
Embodiment 1:
A) will concoct container and be preheated to 150 ℃, and drop into Semen Armeniacae Amarum and fried 2 minutes, reach 85 ℃ to the Semen Armeniacae Amarum surface temperature, add 100 ℃ hot water of 2 times of amounts, acutely boil taking-ups in 5 minutes, peel, standby;
B) take by weighing Semen Armeniacae Amarum 200 grams that cook, Radix Glycyrrhizae 40 grams, Radix Angelicae Sinensis 40 grams, the Radix Angelicae Dahuricae 40 grams, Olibanum 10 grams, Myrrha 10 grams;
C) Semen Armeniacae Amarum, Olibanum and Myrrha are ground into coarse powder, add Oleum Sesami 200 grams and mix pasty state, put into the colloid mushroom and grind into thin cream, standby;
D) Radix Glycyrrhizae, Radix Angelicae Sinensis and the Radix Angelicae Dahuricae are pulverized, the ethanol with 80% is 70 ℃ of following reflux, extract, twice, and 2 hours for the first time, 1 hour for the second time, merge extractive liquid, is condensed into relative density and is the thick paste of 1.30 (50 ℃ record), and was standby;
E) get Oleum Sesami 300 grams in addition and temper half an hour, stop to add Cera Flava 70 gram fusings, when being cooled to 80-90 ℃, the thick paste and the antiseptic that make in thin cream that makes in the adding step c) and the step d) stir evenly, cooling, promptly.
Claims (8)
1. treat the more composition for promoting muscle growing and skin healing of property chronic ulcer of difficulty for one kind, it is characterized in that it is active component and the pharmaceutically acceptable carrier of being made by following parts by weight of Chinese traditional medicine material: Semen Armeniacae Amarum 10-70 part, Radix Glycyrrhizae 1-20 part, Radix Angelicae Sinensis 1-20 part, Radix Angelicae Dahuricae 1-20 part, Olibanum 1-10 part, Myrrha 1-10 part.
2. according to the composition for promoting muscle growing and skin healing of claim 1, active component is wherein made by following parts by weight of Chinese traditional medicine material: Semen Armeniacae Amarum 15-45 part, Radix Glycyrrhizae 1-10 part, Radix Angelicae Sinensis 1-10 part, Radix Angelicae Dahuricae 1-10 part, Olibanum 1-5 part, Myrrha 1-5 part.
3. according to the composition for promoting muscle growing and skin healing of claim 1, active component is wherein made by following parts by weight of Chinese traditional medicine material: Semen Armeniacae Amarum 20-30 part, Radix Glycyrrhizae 4-8 part, Radix Angelicae Sinensis 4-8 part, Radix Angelicae Dahuricae 4-8 part, Olibanum 1-2 part, Myrrha 1-2 part.
4. according to any composition for promoting muscle growing and skin healing among the claim 1-3, it is characterized in that Semen Armeniacae Amarum wherein carries out following processing: will concoct container and be preheated to 100-200 ℃, dropping into Semen Armeniacae Amarum fried 2-3 minute, reach 80-95 ℃ to the Semen Armeniacae Amarum surface temperature, 90-100 ℃ the hot water that adds 2 times of amounts, acutely boil taking-up in 2-8 minute, decortication.
5. a method for preparing the composition for promoting muscle growing and skin healing of the difficult more property of treatment chronic ulcer is characterized in that it comprises the following steps:
A) will concoct container and be preheated to 100-200 ℃, and drop into Semen Armeniacae Amarum and fried 2-3 minute, reach 80-95 ℃ to the Semen Armeniacae Amarum surface temperature, add 90-100 ℃ hot water of 2 times of amounts, acutely boil taking-ups in 2-8 minute, peel, standby;
B) take by weighing the Semen Armeniacae Amarum 10-70 weight portion that cooks, Radix Glycyrrhizae 1-20 weight portion, Radix Angelicae Sinensis 1-20 weight portion, Radix Angelicae Dahuricae 1-20 weight portion, Olibanum 1-10 weight portion, Myrrha 1-10 weight portion;
C) Semen Armeniacae Amarum, Olibanum and Myrrha are ground into powder, standby;
D) Radix Glycyrrhizae, Radix Angelicae Sinensis and the Radix Angelicae Dahuricae are pulverized, the ethanol of using 50-95% is 50-80 ℃ of following reflux, extract, twice, and the time was respectively 2-4 hour and 1-3 hour, and last simmer down to records the thick paste that relative density is 1.30-1.35 for 50 ℃, and is standby;
E), mix, promptly thick paste that makes in fine powder that makes in the step c) and the step d) and pharmaceutically acceptable carrier.
6. according to the preparation method of claim 5, wherein the raw material in the step b) is: Semen Armeniacae Amarum 15-45 weight portion, Radix Glycyrrhizae 1-10 weight portion, Radix Angelicae Sinensis 1-10 weight portion, Radix Angelicae Dahuricae 1-10 weight portion, Olibanum 1-5 weight portion, Myrrha 1-5 weight portion.
7. according to the preparation method of claim 5, wherein the raw material in the step b) is: Semen Armeniacae Amarum 20-30 weight portion, Radix Glycyrrhizae 4-8 weight portion, Radix Angelicae Sinensis 4-8 weight portion, Radix Angelicae Dahuricae 4-8 weight portion, Olibanum 1-2 weight portion, Myrrha 1-2 weight portion.
8. according to the preparation method of claim 5, it comprises the following steps:
A) will concoct container and be preheated to 150 ℃, and drop into Semen Armeniacae Amarum and fried 2 minutes, reach 85 ℃ to the Semen Armeniacae Amarum surface temperature, add 100 ℃ hot water of 2 times of amounts, acutely boil taking-ups in 5 minutes, peel, standby;
B) take by weighing Semen Armeniacae Amarum 200 grams that cook, Radix Glycyrrhizae 40 grams, Radix Angelicae Sinensis 40 grams, the Radix Angelicae Dahuricae 40 grams, Olibanum 10 grams, Myrrha 10 grams;
C) Semen Armeniacae Amarum, Olibanum and Myrrha are ground into coarse powder, add Oleum Sesami 200 grams and mix pasty state, put into the colloid mushroom and grind into thin cream, standby;
D) Radix Glycyrrhizae, Radix Angelicae Sinensis and the Radix Angelicae Dahuricae are pulverized, the ethanol with 80% is 70 ℃ of following reflux, extract, twice, and 2 hours for the first time, 1 hour second time, merge extractive liquid, also is condensed into 50 ℃ to record relative density be 1.30 thick paste, and was standby;
E) get Oleum Sesami 300 grams in addition and temper half an hour, stop heating, add Cera Flava 70 gram fusings, when being cooled to 80-90 ℃, the thick paste and the antiseptic that make in thin cream that makes in the adding step c) and the step d) stir evenly, cooling, promptly.
Priority Applications (1)
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CN 97100165 CN1159940A (en) | 1997-01-15 | 1997-01-15 | Composition for promoting muscle growing and skin healing and preparing method thereof |
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CN 97100165 CN1159940A (en) | 1997-01-15 | 1997-01-15 | Composition for promoting muscle growing and skin healing and preparing method thereof |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109512853A (en) * | 2019-01-24 | 2019-03-26 | 卢洪伟 | A kind of healing powder for treating diabetic wounds ulcer |
CN110090264A (en) * | 2019-05-16 | 2019-08-06 | 王汝平 | One kind, which is applied in combination, repairs scar product formula and application method |
CN110859883A (en) * | 2019-12-18 | 2020-03-06 | 河南中医药大学 | External-use tiger ginseng leaf essential oil for treating skin ulcer |
-
1997
- 1997-01-15 CN CN 97100165 patent/CN1159940A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109512853A (en) * | 2019-01-24 | 2019-03-26 | 卢洪伟 | A kind of healing powder for treating diabetic wounds ulcer |
CN110090264A (en) * | 2019-05-16 | 2019-08-06 | 王汝平 | One kind, which is applied in combination, repairs scar product formula and application method |
CN110859883A (en) * | 2019-12-18 | 2020-03-06 | 河南中医药大学 | External-use tiger ginseng leaf essential oil for treating skin ulcer |
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