CN115983601A - Whole-process big data management platform for coprophilous fungus transplantation - Google Patents
Whole-process big data management platform for coprophilous fungus transplantation Download PDFInfo
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Abstract
The invention discloses a fecal bacteria transplantation full-flow big data management platform, which comprises: the system comprises a fecal strain transplanting management system, a supervision system, a client, a site end and an expert end; the client is used for pushing client information and inquiring information; the fecal fungus transplantation management system comprises a personnel management module, a fecal fungus management module, an equipment management module and a big data analysis module; the big data analysis module analyzes the fecal bacteria to obtain fecal bacteria analysis results, health conditions are obtained according to the analysis results, and intelligent matching of a donor and a receptor is carried out based on the analysis results and the health conditions. The invention provides a standard fecal strain transplantation full-process management platform, which can be used for comprehensively monitoring and analyzing production equipment, transportation equipment and manufacturing process data, storing the data, and facilitating process safety monitoring and retrospective tracing. Through combining personnel, fecal bacteria, capsules, samples and the like through unique identification, the big data comprehensive analysis is convenient to carry out, and big data statistics is provided as a support for the intelligent matching of the receptor and the donor.
Description
Technical Field
The invention belongs to the field of biological and medical health big data sharing platforms, and particularly relates to a fecal bacteria transplantation full-flow big data management platform.
Background
A large amount of symbiotic microorganisms exist in human body, the weight of the symbiotic microorganisms is more than 1Kg, most of the symbiotic microorganisms inhabit human intestinal tracts, and the number of the symbiotic microorganisms is more than 1000 trillion (10 trillion) 14 Order of magnitude) of more than 10 times the total number of human cells. The intestinal flora directly influences the immunity and metabolism of human as a whole and is an immune metabolic organ for human symbiosis.
Fecal bacteria transplantation (FMT) is used as an effective means for reconstructing intestinal flora, functional flora in excrement of healthy people is transplanted into gastrointestinal tracts of patients, new intestinal flora balance is reconstructed, and treatment of intestinal tract and parenteral diseases is realized. Has been used for the treatment and exploratory study of various flora-associated diseases and is considered as a breakthrough medical advance in recent years.
At present, fecal strain transplantation faces difficulty in donor screening, stricter donor management and nonstandard feces collection; links such as bacterial liquid extraction, capsule preparation, sample storage, cold chain transportation are not supervised, any link can influence the final transplanting effect, and once a problem occurs, the final transplanting effect cannot be traced and proved. Meanwhile, the matching of the receptor and the donor does not depend on the experience of doctors, and no big data statistics is taken as a support. The above reasons are one of the reasons that the medical supervision part cannot promote the fecal strain transplantation in a large scale.
Disclosure of Invention
The invention aims to provide a coprophilous fungus transplantation whole-process big data management platform, which provides standardized and normalized process management, big data storage and service for the coprophilous fungus transplantation (FMT) whole process, promotes coprophilous fungus transplantation technology and solves the problems in the prior art.
In order to achieve the above object, the present invention provides a fecal bacteria transplantation full-flow big data management platform, comprising:
the system comprises a client, a station end, an expert end, a fecal strain transplanting management system and a supervision system;
the client is used for pushing client messages and inquiring information;
the fecal fungus transplantation management system comprises a personnel management module, a fecal fungus management module, an equipment management module and a big data analysis module;
the supervision system is used for the whole-process supervision of personnel, production, storage and transportation links;
the client and the supervision platform are respectively connected with the fecal bacteria transplantation management system;
the personnel management module is used for managing personal information of the client;
the fecal management module is used for processing, detecting and managing fecal bacteria in-out information;
the equipment management module is used for managing equipment, and the management comprises registration, deletion, binding, configuration and maintenance;
the big data analysis module analyzes the fecal bacteria to obtain the analysis result of the intestinal flora type and the relative abundance of the genus, obtains the intestinal health condition according to the analysis result, and intelligently matches a donor with a receptor based on the analysis result and the intestinal health condition;
the station side realizes the management of personnel, fecal bacteria and fecal bacteria processing products through the fecal bacteria transplantation management system;
and the expert end is used for auditing the intelligent matching result.
Optionally, the client personal information includes basic information, living habits, health conditions, personal medical history records, family genetic medical history, intestinal type and physical examination reports; the personnel management module presets an effective period of the physical examination report, and carries out validity management on the personnel according to the effective period and whether the physical examination report is qualified or not, if the physical examination report is in the effective period and the physical examination is qualified, the personnel management module judges that the personnel is effective, and if not, the personnel management module judges that the personnel is invalid; sending a physical examination notice to the client before the effective period is reached;
the client is divided into donor persons, autologous persons and recipient persons based on personal information of the client, wherein the feces provided by the donor persons can be selected to be donated or used by self.
Optionally, the fecal management module includes a fecal unit, a bacterial liquid unit, a capsule unit, and a sample retention unit;
the excrement unit judges whether the donor of the excrement, namely the information of the person providing the excrement is effective or not, and if the information is effective, warehousing treatment is carried out; selecting a storage type when the excrement is put in storage, filling acquisition time, acquisition mode, acquisition place, acquisition weight, recording time and abnormal evaluation, and generating excrement serial number, sample reserving serial number and inspection number, wherein the storage type comprises self-storage and donation;
the bacteria liquid unit records bacteria liquid associated excrement number, excrement usage amount, used equipment and consumable material codes and bacteria liquid amount, generates excrement number and sample reserving number, and stores the extraction process data;
the capsule unit records the related bacteria liquid number, the bacteria liquid usage amount, the capsule number, the generated excrement number and the sample reserving number, and stores the manufacturing process data;
the sample reserving unit is used for storing sample reserving information of excrement, bacteria liquid and capsules, and the sample reserving unit is used for abandoning the sample after reserving the preset time after all sample reserving correlation samples are taken out of the warehouse;
excrement and urine unit, fungus liquid unit, capsule unit, stay a kind unit all carry out the record with storage device data that correspond.
Optionally, the device management module adds and deletes the device, generates a serial number corresponding to the device during adding, and adds the device information into the system by using the site, the type and the configuration, wherein the device comprises an extraction device, a freeze-drying device, a storage device, a logistics device and a consumable, the consumable is a disposable consumable, and the logistics device is used for transporting feces, bacteria liquid and capsules in a cold chain manner.
Optionally, the big data analysis module includes a flora analysis unit, a health evaluation unit, and an intelligent matching unit;
the flora analysis unit compares the 16S and macrogene detection sequencing data of the customer fecal sample with flora characteristic data in the big data, and analyzes to obtain the data of the flora type and corresponding abundance in the intestinal tract;
the health assessment unit constructs a health assessment model based on the data of the flora type and corresponding abundance in the intestinal tract and a physical examination report; inputting the types of the flora existing in the intestinal tract of the client and the data of corresponding abundance into a model to obtain a health assessment result;
and the intelligent matching unit intelligently matches the optimal donor according to the analysis of the big data, the type of the flora existing in the intestinal tract of the receptor, the corresponding abundance and the health evaluation result, and the coprophilous bacteria transplantation treatment is carried out.
Optionally, the supervision system includes a personnel supervision module, a production supervision module, and a transportation supervision module;
the personnel supervision module is used for collecting, recording and monitoring physical examination reports before and after excrement collection;
the production supervision module is used for monitoring the bacterial liquid extraction and storage, the capsule manufacturing process, the storage process, the use condition of equipment and consumables in the process and the excrement detection condition;
the transportation module is used for recording and monitoring the cold chain transportation process of the excrement and the logistics transportation process of the capsules.
Optionally, the production supervision module further comprises inventory management, and statistics of using conditions and inventory conditions of feces, bacteria liquid, capsules and reserved samples is performed.
The invention has the technical effects that:
the invention provides a whole-process big data management platform for fecal fungus transplantation, provides a standard fecal collection process, monitors and analyzes equipment and process records adopted in the processes of bacterial liquid extraction, capsule preparation, sample storage and cold chain transportation, stores the equipment and the process records, and is convenient for process safety monitoring and afterwards responsibility tracing. Through combining personnel, fecal bacteria, capsules, samples and the like through unique identification, the big data comprehensive analysis is convenient to carry out, more accurate matching result is provided for customers, and big data statistics is provided for the intelligent matching of the acceptor and the donor as a support. The invention provides standardized and normalized flow management, big data storage and service for the whole process of the coprophilous fungi transplantation (FMT), and has very important significance for promoting the coprophilous fungi transplantation technology by personnel.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this application, are included to provide a further understanding of the application, and the description of the exemplary embodiments of the application are intended to be illustrative of the application and are not intended to limit the application. In the drawings:
FIG. 1 is a schematic illustration of a platform in an embodiment of the present invention;
FIG. 2 is a schematic view of a fecal bacteria bank in an embodiment of the present invention;
FIG. 3 is a diagram of a device management module according to an embodiment of the present invention;
fig. 4 is a schematic diagram of a monitoring system according to an embodiment of the present invention.
Detailed Description
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to the embodiments with reference to the attached drawings.
Example one
As shown in fig. 1 to 4, the present embodiment provides a fecal bacteria transplantation full-flow big data management platform, including:
the total-flow big data management platform for fecal fungus transplantation provided by the embodiment comprises a personnel database, a fecal fungus database, an equipment management module and a big data analysis module. The periphery comprises a site, a client, an expert and a supervision platform.
And the expert end is related to the intelligent matching unit in the big data analysis module. In the actual construction of the intelligent matching unit, besides relying on big data support, the experience of experts is required to be refined to form a screening rule. However, intelligent matching only provides reference for fecal bacteria matching, so that the subsequent workload is reduced, the medical industry is strict, and finally, a matching result needs to be selected by an expert according to the intelligent matching result.
The stations are distributed in the bacteria-making centers of different cities after being deployed as a platform, and exchange data with the core part through a network. Each station can independently manage the personnel, the fecal strain storeroom and the equipment.
As the excrement collection has the problems of time limitation, trouble in cross-city transportation and the like, the excrement collection can be served as near as possible to avoid the problems. The site is arranged in different cities and is responsible for relevant work of excrement collection in urban areas and peripheral areas, and the functions of the site comprise personnel management, excrement collection, production and processing, low-temperature storage and the like.
The client is a client and can provide functions of information inquiry, progress pushing, reservation and the like after being bound with the platform through APP, public numbers and the like.
The human libraries include donor libraries, autologous libraries, recipient libraries. The donor, the self-body and the receptor can be respectively classified and managed.
The donor is a feces donator, the self-body is a feces self-storage person, and the receptor is a fecal strain user.
The personnel library can record the basic information, living habits, health conditions, personal medical history records, family genetic medical history, intestinal type and the like of the donor personnel, the self-stored personnel and the recipient personnel and automatically generate personnel numbers.
The personnel library can record the personnel physical examination report and carry out validity management on the donor according to whether the physical examination report is qualified or not and the set valid period. One week before the clinical period, a physical examination notice is given. The system automatically marks the donor as invalid and does not perform the correlation operation for the unqualified person or the overdue person. The second physical examination is eligible or the timely supplemental physical examination report can be flagged as valid.
The fecal bacteria storehouse comprises a fecal storehouse, a bacteria liquid storehouse, a capsule storehouse and a sample reserving storehouse.
The fecal bacteria library provides functions of managing the incoming and outgoing libraries, inquiring the inventory, inquiring the documents and counting.
The excrement can be used after being put in storage, personnel storage personnel can be associated when the excrement is put in storage, the excrement and the personnel storage personnel can be associated when the donor is effective, and the excrement can be normally recorded into the excrement storage.
Donor excrement can be selectively stored in a self-storage or donation type, and other person excrement can be selectively stored in a self-storage type. During recording, the feces collection time, the feces collection place, the feces collection mode, the feces collection weight, the feces collection time, the feces collection abnormality evaluation and the feces collection registry as an accessory are required to be filled in faithfully. The collection mode comprises field collection, door-to-door collection, consignment and the like, the door-to-door collection, consignment and the like relate to excrement cold chain transportation, and related cold chain transportation equipment numbers need to be related so as to facilitate the transportation process tracing.
After the basic warehousing information is filled, excrement storage equipment and storage positions are associated in an intuitive selection mode, sample storage equipment and storage positions are reserved, and excrement numbers, sample numbers and inspection numbers are automatically generated. And connecting a printer to print the bar code and correspondingly pasting. The feces to be checked need 16S and macro gene detection, and the platform and the detection system can be connected with an interface to automatically acquire checking information, progress and result query.
And (4) performing bacterial liquid extraction, capsule preparation, bacterial liquid warehousing and capsule warehousing on the feces in case of non-detection report and qualified detection report. The feces are not qualified in the inspection report, and the feces, the reserved sample, the bacterial liquid prepared from the feces and the capsule are all subjected to waste treatment, so that the feces and the reserved sample can not be used for subsequent processing.
When the bacterial liquid is put in storage, the excrement serial number is scanned through a code scanning gun or excrement in the excrement and bacteria storage can be correlated through system screening, and the weight of the used excrement, the used consumable material code and the generated bacterial liquid amount are filled. After the basic warehousing information is filled, associating the bacteria liquid storage equipment and the storage position, reserving a sample storage equipment and the storage position in an intuitive selection mode, and automatically generating a bacteria liquid number and a reserving sample number. And connecting a printer to print the bar code and correspondingly pasting.
When the capsules are put in storage, the bacteria liquid serial numbers are scanned through a code scanning gun or the bacteria liquid of the associable bacteria liquid storage is screened through a system, and the used bacteria liquid amount and the generated capsule amount are filled. After the basic information of the storage is filled, the capsule storage equipment and the storage position are associated in an intuitive selection mode, the sample storage equipment and the storage position are reserved, and the capsule number and the sample number are automatically generated. And connecting a printer to print the bar code and correspondingly pasting the bar code.
Reserving excrement samples, bacterium liquid samples and capsule samples in a sample reserving library, timing after all the related samples are taken out of the library, and taking out of the library as waste after five years of reservation.
The effectiveness of the donor directly influences the use of the excrement products provided by the donor, namely the donor is unqualified, and the excrement and related products provided from the last physical examination to the current physical examination are all discarded; the physical examination is qualified, each excrement is qualified, and the excrement and related products provided from the last physical examination to the current physical examination can be discharged.
The self-stored product is only allowed to be used by oneself, and the donated product can be used for donors, autodonors and acceptors.
Statistics can respectively display the accumulated storage amount, the accumulated export amount and the current stock amount of the excrement, the bacteria liquid and the capsules. Screening can be performed according to self-preservation, donation, intestinal type and the like.
The equipment management module comprises extraction equipment management, freeze-drying equipment management, storage equipment management, logistics equipment management and consumable material management. All devices need to add a device ID to the system to obtain data.
The extraction equipment is bacteria liquid automatic extraction equipment, and can stir and filter the excrement under the low-oxygen and low-temperature environment to finally obtain bacteria liquid. The extraction device is internally provided with an RFID and a 4G module. The extraction equipment reads the ID number of the consumable through the RFID module, and the consumable ID number is compared through the 4G module uploading server, and the equipment is started only if the consumable is not used. The 4G module can upload operation process data, such as temperature, oxygen content and other parameters to the server in real time. The equipment can be added, deleted, bound by a client and configured with parameters.
The freeze-drying equipment freeze dryer can upload parameters such as temperature and vacuum degree through a 4G module. Additions and deletions can be made to the device.
The storage equipment is a low-temperature refrigerator, can store excrement, bacteria liquid and capsules at the temperature of minus 86 ℃, and can upload the temperature in the refrigerator through an external 4G module. Equipment addition, deletion, capacity setting and capacity maintenance can be performed.
The logistics equipment is a low-temperature transfer box, is provided with a GPS (global positioning system) positioning module and a 4G (global positioning system) module, and can upload temperature and position information in real time. Equipment additions may be made. The method is used for cold chain transportation of excrement, bacteria liquid and capsules.
The consumable is a disposable consumable special for the extraction equipment, the RFID tag is attached to the outer surface of the consumable, the consumable used by the extraction equipment can be added through the ID, and a customer and specified equipment can be bound to batches, sales time, use states, use periods and the like.
The consumable management module provides a consumable RFID information input interface, so that new consumables can be conveniently introduced. After the consumable is authenticated by swiping a card, the module can record the ID of the used equipment and the use time, and is marked as a used state and can not be used again. The cross infection and the like caused by incomplete sterilization of the consumable materials due to secondary use are avoided, the production safety is fundamentally ensured, and effective supervision measures and tracing means are provided for later medical supervision departments.
The big data analysis module comprises a flora analysis module, a health assessment analysis module and an intelligent matching module.
The flora analysis module detects sequencing data according to 16S and macrogene of personnel, compares the sequencing data with flora characteristic data in big data, and further analyzes the type and corresponding abundance of flora in intestinal tracts.
The imbalance of intestinal flora is related to more than 95% of diseases of human body. The species and the proportion of the bacteria in the intestinal tract are in a range, and are as compared with the conventional blood, white blood cells and platelets have corresponding range values, and the absence or the exceeding range is abnormal, and the absence or the different range corresponds to different diseases.
The flora type and the corresponding abundance degree of the customer can be obtained through the flora analysis module, the possibility of the attack of various diseases of the customer is judged by judging the ratio of the flora type in the customer body to the corresponding ratio, and if the flora type is in the normal range, the possibility of the health of the customer is higher because the flora type is also in the respective reasonable ratio range. If there is a loss of the flora type or the flora proportion closely related to the disease is above the normal value, it can be assumed that the client has a high probability of suffering from the disease.
The health evaluation module compares the obtained type and abundance of the intestinal flora in the intestinal tract with the types and abundances of the intestinal flora of healthy people and people with corresponding diseases in the big data respectively, and analyzes the intestinal flora intestinal health condition, and possible risks or diseases. Such as obesity, intestinal inflammation, etc.
The health assessment module is used for researching and obtaining the corresponding relation between the intestinal flora and the diseases by relying on a large number of personnel flora types and corresponding abundance data in the database and combining the physical examination result, so that a health assessment model is established.
The intelligent matching module is connected with the personnel warehouse and the fecal bacteria warehouse, and intelligently matches products of the best donors for the recipients through big data analysis so as to achieve the best treatment effect.
The supervision platform uses excrement as an entry point, associates physical examination conditions of people before and after excrement collection, diet and living conditions before excrement collection, excrement detection conditions and consumable service conditions, collects cold chain transportation data after excrement collection, stores data after excrement collection, extracts process data from bacterial liquid, stores the bacterial liquid storage data, makes capsule manufacturing process data, stores capsule data and cold chain transportation data of capsules through various devices, collects records, and records abnormal data of each module library and gives an alarm. If the physical examination is unqualified, corresponding fecal bacteria is marked abnormally, a notice is sent, if the fecal and fecal detection report is unqualified, the fecal is marked as abnormal independently, in the manufacturing and transportation process, due to the particularity of the fecal and the bacterial liquid, when the external environment changes, the detection result or the fecal bacteria effect is affected, and therefore a warning needs to be sent, specifically, in the cold chain transportation and storage process, due to power failure or illegal opening of a door and the like, the temperature is higher than a set limit value, and at the moment, the temperature is abnormal (see international consensus and Shanghai standard). In the manufacturing process, the temperature is set to be 13.5 ℃, abnormality occurs when the temperature exceeds 15 ℃ midway, and abnormality occurs when the oxygen content exceeds 10%. The alarm mode is platform alarm and wechat message push. The data is permanently stored by the server and is not modifiable. And guarantee is provided for the supervision of the whole process. Provides effective supervision measures and tracing means for medical supervision departments.
The above description is only for the preferred embodiment of the present application, but the scope of the present application is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present application should be covered within the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.
Claims (7)
1. The utility model provides a coprophilous fungi transplantation full-process big data management platform which characterized in that includes:
client, site, expert, fecal fungus transplantation management system, and supervision system;
the client is used for pushing client information and inquiring information;
the fecal fungus transplantation management system comprises a personnel management module, a fecal fungus management module, an equipment management module and a big data analysis module;
the supervision system is used for the whole-process supervision of personnel, production, storage and transportation links;
the client and the supervision platform are respectively connected with the fecal strain transplantation management system;
the personnel management module is used for managing personal information of the client;
the fecal management module is used for processing, detecting and managing fecal bacteria in-out information;
the equipment management module is used for managing the equipment, and the management comprises registration, deletion, binding, configuration and maintenance;
the big data analysis module analyzes the fecal bacteria to obtain the analysis result of the intestinal flora type and the relative abundance of the genus, obtains the intestinal health condition according to the analysis result, and intelligently matches a donor with a receptor based on the analysis result and the intestinal health condition;
the station end realizes the management of personnel, fecal bacteria and fecal bacteria processing products through the fecal bacteria transplanting management system;
and the expert end is used for auditing the intelligent matching result.
2. The fecal bacteria transplantation full-flow big data management platform according to claim 1, wherein the customer personal information includes basic information, living habits, health conditions, personal medical history records, family genetic medical history, intestinal type, physical examination reports; the personnel management module presets an effective period of the physical examination report, and carries out validity management on the personnel according to the effective period and whether the physical examination report is qualified or not, if the physical examination report is in the effective period and the physical examination is qualified, the personnel management module judges that the personnel is effective, and if not, the personnel management module judges that the personnel is invalid; before the effective period is reached, a physical examination notice is sent to the client;
the client is divided into donor persons, autologous persons and recipient persons based on personal information of the client, wherein the feces provided by the donor persons can be selected to be donated or used by self.
3. The fecal strain transplanting full-flow big data management platform according to claim 1, wherein the fecal strain management module comprises a fecal unit, a bacterial liquid unit, a capsule unit, a sample retention unit;
the excrement unit judges whether the donor of the excrement, namely the information of the person providing the excrement is effective or not, and if the information is effective, warehousing treatment is carried out; selecting a storage type when the excrement is put in storage, filling acquisition time, acquisition mode, acquisition place, acquisition weight, recording time and abnormal evaluation, and generating excrement serial number, sample reserving serial number and inspection number, wherein the storage type comprises self-storage and donation;
the bacteria liquid unit records bacteria liquid associated excrement number, excrement usage amount, used equipment and consumable material codes and bacteria liquid amount, generates excrement number and sample reserving number, and stores the extraction process data;
the capsule unit records the related bacteria liquid number, the bacteria liquid usage amount, the capsule number, the generated excrement number and the sample reserving number, and stores the manufacturing process data;
the sample reserving unit is used for storing sample reserving information of excrement, bacterial liquid and capsules, and the sample reserving unit is used for discarding the sample after reserving the preset time after all sample reserving correlation samples are discharged from the warehouse;
excrement unit, fungus liquid unit, capsule unit, stay a kind unit all will correspond memory location and storage device data record.
4. The platform of claim 1, wherein the equipment management module performs addition and deletion operations on equipment, generates a number corresponding to the equipment during addition, and adds equipment information to the system, wherein the equipment information includes a site, a type and a configuration, and the equipment information includes extraction equipment, freeze-drying equipment, storage equipment, logistics equipment and consumables, and the consumables are disposable consumables used for cold chain transportation of excrement, bacteria liquid and capsules.
5. The whole-flow big data management platform for fecal fungus transplantation according to claim 1, wherein the big data analysis module comprises a flora analysis unit, a health evaluation unit and an intelligent matching unit;
the flora analysis unit compares the 16S and macrogene detection sequencing data of the client fecal sample with flora characteristic data in the big data, and analyzes to obtain the types of flora existing in the intestinal tract and the data of corresponding abundance;
the health assessment unit constructs a health assessment model based on the data of the flora type and corresponding abundance in the intestinal tract and a physical examination report; inputting the types of the flora existing in the intestinal tract of the client and the data of corresponding abundance into a model to obtain a health assessment result;
the intelligent matching unit intelligently matches the best donor according to the analysis of the big data and the flora type, the corresponding abundance and the health assessment result existing in the intestinal tract of the receptor.
6. The coprophilous transplantation full-flow big data management platform according to claim 1, wherein the supervision system comprises a personnel supervision module, a production supervision module and a transportation supervision module;
the personnel supervision module is used for collecting, recording and monitoring physical examination reports before and after excrement collection;
the production supervision module is used for monitoring the bacterial liquid extraction and storage, the capsule manufacturing process, the storage process, the use condition of equipment and consumables in the process and the excrement detection condition;
the transportation module is used for recording and monitoring the cold chain transportation process of the excrement and the logistics transportation process of the capsules.
7. The platform of claim 6, wherein the production supervision module further comprises inventory management, statistics of usage and inventory of feces, bacteria liquid, capsules and reserved samples.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106192020A (en) * | 2016-07-07 | 2016-12-07 | 北京航空航天大学 | A kind of method that microorganism builds the flora storehouse transplanted for flora when utilizing autologous health status |
| KR20190004586A (en) * | 2017-07-04 | 2019-01-14 | (주)바이오일레븐 | The method of stool suggestion for FMT |
| CN111312353A (en) * | 2019-11-25 | 2020-06-19 | 江西善行生物科技有限公司 | Traceability system for flora and donor immune information |
| CN111681733A (en) * | 2020-04-30 | 2020-09-18 | 厦门承葛生物科技有限公司 | Method for screening intestinal flora transplantation donor |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106192020A (en) * | 2016-07-07 | 2016-12-07 | 北京航空航天大学 | A kind of method that microorganism builds the flora storehouse transplanted for flora when utilizing autologous health status |
| KR20190004586A (en) * | 2017-07-04 | 2019-01-14 | (주)바이오일레븐 | The method of stool suggestion for FMT |
| CN111312353A (en) * | 2019-11-25 | 2020-06-19 | 江西善行生物科技有限公司 | Traceability system for flora and donor immune information |
| CN111681733A (en) * | 2020-04-30 | 2020-09-18 | 厦门承葛生物科技有限公司 | Method for screening intestinal flora transplantation donor |
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