CN115957157B - Algae composite extraction composition for homogenizing skin color and repairing skin and application thereof - Google Patents
Algae composite extraction composition for homogenizing skin color and repairing skin and application thereof Download PDFInfo
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- 239000000203 mixture Substances 0.000 title claims abstract description 39
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- 238000000605 extraction Methods 0.000 title abstract description 9
- 239000002131 composite material Substances 0.000 title description 2
- 239000000284 extract Substances 0.000 claims abstract description 42
- 241000206753 Gloiopeltis Species 0.000 claims abstract description 18
- 235000017337 Persicaria hydropiper Nutrition 0.000 claims abstract description 11
- 240000000275 Persicaria hydropiper Species 0.000 claims abstract description 11
- 229940064399 botrytis cinerea extract Drugs 0.000 claims abstract description 9
- 235000003724 spirulina extract Nutrition 0.000 claims abstract description 8
- 239000002537 cosmetic Substances 0.000 claims description 12
- 150000004676 glycans Chemical class 0.000 claims description 10
- 229920001282 polysaccharide Polymers 0.000 claims description 10
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 9
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 8
- 238000009210 therapy by ultrasound Methods 0.000 claims description 6
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- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 4
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 3
- 239000002453 shampoo Substances 0.000 claims description 2
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- 239000002994 raw material Substances 0.000 abstract description 6
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- 102000003425 Tyrosinase Human genes 0.000 description 20
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- 238000012360 testing method Methods 0.000 description 12
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- OHDRQQURAXLVGJ-HLVWOLMTSA-N azane;(2e)-3-ethyl-2-[(e)-(3-ethyl-6-sulfo-1,3-benzothiazol-2-ylidene)hydrazinylidene]-1,3-benzothiazole-6-sulfonic acid Chemical compound [NH4+].[NH4+].S/1C2=CC(S([O-])(=O)=O)=CC=C2N(CC)C\1=N/N=C1/SC2=CC(S([O-])(=O)=O)=CC=C2N1CC OHDRQQURAXLVGJ-HLVWOLMTSA-N 0.000 description 8
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- 241000123650 Botrytis cinerea Species 0.000 description 3
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- 230000008859 change Effects 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 239000011550 stock solution Substances 0.000 description 3
- 239000012224 working solution Substances 0.000 description 3
- 235000016425 Arthrospira platensis Nutrition 0.000 description 2
- 240000002900 Arthrospira platensis Species 0.000 description 2
- 241000222455 Boletus Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
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- 239000006210 lotion Substances 0.000 description 2
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- 238000001556 precipitation Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000002390 rotary evaporation Methods 0.000 description 2
- 238000000527 sonication Methods 0.000 description 2
- 238000003809 water extraction Methods 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 241000978499 Brunnichia ovata Species 0.000 description 1
- 241001339217 Caulerpa lentillifera Species 0.000 description 1
- 241000195628 Chlorophyta Species 0.000 description 1
- 241000900541 Delesseria sanguinea Species 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 description 1
- 108090000526 Papain Proteins 0.000 description 1
- 241000199919 Phaeophyceae Species 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 241000206572 Rhodophyta Species 0.000 description 1
- 241001114003 Seira Species 0.000 description 1
- 241000006302 Usnea Species 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- OHDRQQURAXLVGJ-AXMZSLBLSA-N azane;(2z)-3-ethyl-2-[(z)-(3-ethyl-6-sulfo-1,3-benzothiazol-2-ylidene)hydrazinylidene]-1,3-benzothiazole-6-sulfonic acid Chemical compound [NH4+].[NH4+].S/1C2=CC(S([O-])(=O)=O)=CC=C2N(CC)C\1=N\N=C1/SC2=CC(S([O-])(=O)=O)=CC=C2N1CC OHDRQQURAXLVGJ-AXMZSLBLSA-N 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000006184 cosolvent Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- MHUWZNTUIIFHAS-CLFAGFIQSA-N dioleoyl phosphatidic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(COP(O)(O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC MHUWZNTUIIFHAS-CLFAGFIQSA-N 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 229960004502 levodopa Drugs 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- -1 pH adjusters Substances 0.000 description 1
- 229940055729 papain Drugs 0.000 description 1
- 235000019834 papain Nutrition 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- USHAGKDGDHPEEY-UHFFFAOYSA-L potassium persulfate Chemical compound [K+].[K+].[O-]S(=O)(=O)OOS([O-])(=O)=O USHAGKDGDHPEEY-UHFFFAOYSA-L 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000012599 radical scavenging assay Methods 0.000 description 1
- 238000002407 reforming Methods 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229940082787 spirulina Drugs 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000037072 sun protection Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- LEAHFJQFYSDGGP-UHFFFAOYSA-K trisodium;dihydrogen phosphate;hydrogen phosphate Chemical compound [Na+].[Na+].[Na+].OP(O)([O-])=O.OP([O-])([O-])=O LEAHFJQFYSDGGP-UHFFFAOYSA-K 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The application provides an alga compound extraction composition for homogenizing skin color and repairing skin, which comprises red leaf alga extract, botrytis cinerea extract, gloiopeltis alga extract and Bonatate spirulina extract. The raw materials of the composition are natural and healthy, and can effectively remove free radicals, repair skin, lighten black spots and even skin color.
Description
Technical Field
The application belongs to the field of plant extracts and cosmetics, and particularly provides an alga compound extraction composition for homogenizing skin color and repairing skin and application thereof.
Background
As ideas change, users' attention and demands on the health of cosmetic raw materials have been increasing. Plant extract raw materials are increasingly gaining importance in the cosmetic industry. In addition to various land plants, plants such as seaweed, which have high yields and excellent growing environments, are also good cosmetic raw materials. The seaweed contains a large amount of various brown algae, red algae, green algae and the like with different types and different growing environments, and the polysaccharide, protein, small peptide and other small molecular active substances contained in the seaweed have various functions of regulating immunity, resisting inflammation, resisting oxidation and the like.
The seaweed has rich variety and multiple functions, has good development prospect, and has rich development potential in the aspects of selecting proper seaweed variety, identifying and reforming the seaweed extract and the functions of the components in the seaweed extract.
Disclosure of Invention
In order to better develop the cosmetic raw material resource of seaweed extract, the applicant has developed and prepared various seaweed extracts and compositions thereof, and has achieved good effects in practical use; the applicant has further studied the method of further improving the activity of seaweed extracts, as required to maintain their natural healthy properties.
In one aspect, the present application provides an algae complex extract composition for evening skin color, repairing skin, comprising red leaf algae extract, botrytis cinerea extract, gloiopeltis furcata extract, and Bonatate spirulina extract.
Further, the weight ratio of red leaf algae extract, botrytis cinerea extract, gloiopeltis furcata extract and Botrytis cinerea extract in the composition is 1-3:0.2-0.8:5-20:0.5-3; preferably in a weight ratio of 2:0.5:10:1.
Further, the composition comprises 2wt% of red leaf algae extract, 0.5wt% of Botrytis cinerea extract, 10wt% of gloiopeltis extract, 1wt% of Bonatate spirulina extract, 0.3wt% of p-hydroxyacetophenone, 1, 2-hexanediol 1%, 10wt% of glycerin, 5wt% of butanediol, and 70.2wt% of water.
Further, the polysaccharide content of the gloiopeltis extract in the composition is more than 65wt% and is modified by ultrasonic treatment.
Further, the concentration of the Usnea hainanensis extract in the ultrasonic treatment modification is 5g/L, and the ultrasonic sound intensity is 150W/cm 2 The ultrasonic volume is 80mL; the pH in the ultrasonic system is 8.
Further, the ultrasonic treatment method comprises the following steps: the Gloiopeltis extract was formulated into a 5g/L solution using PBS at pH 8,0.05M, and 80mL of the solution was placed in a 200mL beaker; 25 ℃ and ultrasonic sound intensity of 150W/cm 2 The frequency was 20kHz, the pulse time was 2 seconds, the interval was 2 seconds, and the sonication was carried out for 30 minutes.
In another aspect, the present application provides a cosmetic comprising the above composition.
In another aspect, the application provides the use of the composition in preparing a cosmetic for skin repair with uniform skin color.
Further, the cosmetics are essence, toner, face cleansing cream, skin moisturizing cream, sun protection cream, face cream, facial mask, cleansing water, foundation, bath lotion and shampoo.
Red leaf algae, red vine fern algae, gloiopeltis algae, boletus and boletus spirulina in the application can select various specific subspecies; the polysaccharide extract is commercially available in various products, and can be prepared by various extraction methods known in the art, including but not limited to the most common water extraction and alcohol precipitation method, and the polysaccharide content in the extract can be changed within the range of 30% -80% by properly arranging parameters such as crushing method, alcohol consumption, extraction times and the like, so that the cost, convenience and effect are comprehensively considered, and the extract with the polysaccharide content of 55-65% is used in the examples (see the detailed description).
The effectiveness of the sonication is affected by factors such as the intensity of sound, the volume of solution, the shape of the container, etc., and the container used in the examples of the present application is a 200mL beaker with 80mL of solution. Subsequent verification of conventional containers of similar volumes, such as various beakers, centrifuge tubes, triangular flasks, etc. having volumes greater than 100mL but less than 250mL, can achieve similar results.
In addition to the above ingredients, other ingredients meeting relevant regulatory regulations may be used in the cosmetics according to the need, and these ingredients include, but are not limited to, solvents, cosolvents, pH adjusters, antioxidants, stabilizers, fillers, emulsifiers, thickeners, and the like.
Drawings
FIG. 1 is a graph showing the relationship between ultrasonic sound intensity and ABTS clearance and tyrosinase inhibitory activity.
FIG. 2 is a graph showing the relationship between ultrasound system pH and ABTS clearance and tyrosinase inhibitory activity.
Fig. 3 shows the change in the area of the stain in the actual skin test.
Fig. 4 shows the variation trend of skin color uniformity in an actual skin test.
Detailed Description
Example 1 materials and basic methods
Raw materials and equipment:
the red leaf algae (DELESSERIA SANGUINEA) extract (with the polysaccharide content of more than 55 wt%) and the Botrytis cinerea (CAULERPA LENTILLIFERA) extract (with the polysaccharide content of more than 65 wt%) are self-made by the applicant, and the extraction method is to extract algae powder by using a water extraction and alcohol precipitation method, and 0.2% of papain is added in the Botrytis cinerea extraction for auxiliary extraction.
The extracts of Gloiopeltis (GLOIOPELTIS FURCATA) and Bonateglinium (SPIRULINA PLATENSIS) were purchased from Seira Biotechnology Co., ltd, and the polysaccharide content was greater than 65wt%.
Other non-illustrated excipients and reagents used in the experiments were purchased from qualified manufacturers.
Ultrasonic breaker: the sound VCX750, power 750w, uses a standard probe 13mm in diameter in the experiment (sound intensity is calculated based on this probe area).
Basic composition of the composition:
2wt% of red leaf algae extract, 0.5wt% of Botrytis cinerea extract, 10wt% of gloiopeltis extract, 1wt% of Bonatate spirulina extract, 0.3wt% of p-hydroxyacetophenone, 1, 2-hexanediol 1%, 10wt% of glycerin, 5wt% of butanediol and 70.2wt% of water.
ABTS radical scavenging assay
Adding distilled water into ABTS diammonium salt to prepare 7mmol/L stock solution; adding distilled water into potassium peroxodisulfate to prepare a stock solution with the concentration of 2 mol/L; mixing two stock solutions in equal volume, and standing at dark room temperature for 12 hours to obtain an ABTS working solution; diluting the ABTS working solution to the absorbance of 734nm of about 0.7; fully mixing a sample solution to be detected (or distilled water control) with the diluted ABTS working solution (or distilled water blank), standing for 5 minutes, and recording the absorbance at 734 nm; ABTS radical clearance was calculated as follows:
clearance = [1- (A) Sample of -A Blank space )/A Control ]×100％
Three replicates were averaged.
Tyrosinase inhibition activity assay
Tyrosinase inhibitory activity was detected using a tyrosinase activity detection kit (Beijing Box Biotechnology Co., ltd., based on the DOPA dye method, using substrate buffer solution reagent 1) therein and merck tyrosinase standard (T3824, CAS number 9002-10-2, formulated as 30ug/mL tyrosinase solution); the following system was formulated: system 1: reagent 1; system 2: reagent 1+ tyrosinase solution; system 3: a reagent 1+ sample; system 4: reagent 1+ sample+tyrosinase solution; wherein the tyrosinase solution is added last, and other components in the system react in a water bath at 30 ℃ for 10 minutes before the tyrosinase solution is added; immediately after the tyrosinase solution was added, light absorption at 475nm was detected; tyrosinase inhibition was calculated according to the following formula:
tyrosinase inhibition rate= [1- (a) 4 -A 3 /A 2 -A 1 )]×100％
Three replicates were averaged.
Skin tone uniformity test
Images of the entire face were acquired using a Canfield's facial image analyzer, VISIA-CR, and the percentage of the area of the stain was analyzed for Mirr Photo Tools using additional image analysis software, melanin specific image skin tone uniformity variation.
EXAMPLE 2 ultrasonic modified polysaccharide experiments
According to researches on seaweed extracts for many years, the applicant prepares a composition of red leaf seaweed, botrytis cinerea, gloiopeltis and Bonatate spirulina extracts, and preliminary experiments show that the composition has the effects of whitening skin, fading color spots, homogenizing skin colors, repairing creeping, resisting inflammation and the like as a purely natural composition.
In order to further improve the efficacy of the composition, without introducing other chemical components that may cause consumer concerns, the applicant tried to make an ultrasonic physical modification of the extract of gloiopeltis maxima in the composition, and studied and determined suitable concentration, temperature, ultrasonic mode, etc. indices using the antioxidant and tyrosinase inhibitory activity research methods described in example 1: concentration 5g/L,25 degrees celsius, frequency 20kHz, pulse time 2 seconds, interval 2 seconds, ultrasound time 30 minutes (the ultrasound time including pulse and interval time, detailed figures and data not shown for reasons of space) and further determines the appropriate ultrasound intensity index and pH index.
Ultrasonic sound intensity:
in the experiment, 80mL of 5g/L concentration gloiopeltis alga aqueous solution is added into a 200mL beaker, and ultrasonic parameters are: 25 ℃ and the frequency is 20kHz, the pulse time is 2 seconds, the interval is 2 seconds, and the ultrasonic time is 30 minutes; rotary evaporation concentration and freeze drying; oxidation resistance (1 mg/mL solution) and tyrosinase inhibition rate (10 mg/mL solution) at different sound intensities were collected, and the results are shown in FIG. 1.
The results showed that ABTS clearance gradually increased from 40% to a level of around 70% with increasing ultrasonic sound intensity and corresponding disintegration of sugar chains; however, the trend of tyrosinase inhibition activity is different, and the ultrasonic sound intensity with the strongest inhibition rate appears at 150W/cm 2, On the left and right, the inhibition rate is rather lowered when the ultrasonic sound intensity is stronger, and it is presumed that this is related to the change in the modification condition of the sugar chain.
In summary, 150W/cm is preferred 2, The sound intensity was modified ultrasonically (ABTS clearance rate was not significantly changed at higher sound intensities).
pH aspect:
the experimental conditions are as follows: the gloiopeltis extract is prepared into a solution with the concentration of 5g/L by using PBS (disodium hydrogen phosphate-sodium dihydrogen phosphate) of 0.05M (the dissolution of the gloiopeltis extract has no obvious influence on the pH of the solution); 80mL of the solution was added to a 200mL beaker with ultrasonic parameters of: 150W/cm 2, 25 ℃ and 20kHz frequency, 2 seconds pulse time, 2 seconds interval and 30 minutes ultrasonic time; rotary evaporation concentration and freeze drying; oxidation resistance (1 mg/mL solution) and tyrosinase inhibition rate (10 mg/mL solution) at different pH were collected, and the results are shown in fig. 2.
The results show that ultrasound at different pH had no significant effect on oxidation resistance (except pH 3), tyrosinase inhibitory activity reached a maximum (54.5%) at pH 8, and significantly decreased at higher.
Practical skin test of the composition of example 3
A composition usable as skin care lotion was prepared by adding p-hydroxyacetophenone, 1, 2-hexanediol, glycerin, butylene glycol and water to the seaweed extract as described in example 1. The specific composition comprises:
composition 1 prepared using an unmodified gloiopeltis extract;
using 150W/cm 2, Composition 2 prepared by ultrasonic modification of gloiopeltis extract at a sound intensity of pH 8;
using 240W/cm 2, Composition 3 prepared by ultrasonic modification of gloiopeltis extract with sound intensity and pH 8 sound intensity;
the actual skin experiments were performed using the three compositions described above, in which 85 testers were recruited inside the applicant's business, the basic situation being:
35 men, aged between 30-48 years; 50 females, between ages 27 and 46; no obvious skin disease (such as severe acne, dermatitis, etc.) exists in the testers, and the face has mild to moderate color spots (the number of the color spots with the diameter of about 2-6mm is 2-5, which can be distinguished by naked eyes); the personnel participating in the test are all indoor staff of the enterprise, and the condition of long-term outdoor work is avoided. All testers completed the experiment.
The test time was 6 weeks, spring (3-4 months), and the relevant index was measured weekly by the tester using the apparatus described in example 1, and the average value was plotted.
The test person did not use any cosmetics other than the test article during the test, and 25 test persons for each of compositions 1-3 and 10 test persons did not use the composition of the present application as a control. The test results are shown in fig. 3 and 4:
in terms of the percentage of the area of the colored spots, the area of the colored spots overall tended to increase due to the increase in the intensity of ultraviolet light in spring and the outdoor activities of most people, but the three compositions still achieved a more pronounced effect of inhibiting the area of the colored spots compared to the control.
The results in terms of skin tone uniformity are substantially similar to the results in terms of percent panel area, and while the overall uniformity percentage is increased (i.e., tends to be non-uniform), the three compositions still achieve a more pronounced uniform skin tone effect than the control.
In conclusion, the three compositions can have the effects of fading color spots and homogenizing skin colors; as with the trend of tyrosinase activity inhibition effect in example 2, the effect of composition 2 was superior to that of compositions 1 and 3.
Claims (3)
1. Use of an algae complex extract composition in preparing cosmetics for homogenizing skin color and repairing skin, wherein the composition comprises red leaf algae extract, botrytis cinerea extract, gloiopeltis furcata extract and Bonatate spirulina extract; polysaccharide content of the gloiopeltis extract in the composition is more than 65 weight percent, and the composition is modified by ultrasonic treatment; the ultrasonic treatment modification method comprises the following steps: the Gloiopeltis extract was formulated into a 5g/L solution using PBS at pH 8,0.05M, and 80mL of the solution was placed in a 200mL beaker; 25 ℃ and ultrasonic sound intensity of 150W/cm 2 The frequency is 20kHz, the pulse time is 2 seconds, the interval is 2 seconds, and the ultrasonic treatment is carried out for 30 minutes; the weight ratio of red leaf algae extract, botrytis cinerea extract, gloiopeltis furcata extract and Bonatate spirulina extract in the composition is 2:0.5:10:1.
2. The use according to claim 1, wherein the composition consists of 2wt% of red leaf algae extract, 0.5wt% of Botrytis cinerea extract, 10wt% of gloiopeltis extract, 1wt% of bolsteri spirulina extract, 0.3wt% of p-hydroxyacetophenone, 1, 2-hexanediol 1%, 10wt% of glycerol, 5wt% of butanediol, 70.2wt% of water.
3. The use according to claim 1, wherein the cosmetic is a essence, a toner, a cleanser, a emollient milk, a sun cream, a face cream, a mask, a makeup remover, a foundation, a body wash, or a shampoo.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310102778.2A CN115957157B (en) | 2023-02-13 | 2023-02-13 | Algae composite extraction composition for homogenizing skin color and repairing skin and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310102778.2A CN115957157B (en) | 2023-02-13 | 2023-02-13 | Algae composite extraction composition for homogenizing skin color and repairing skin and application thereof |
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| Publication Number | Publication Date |
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| CN115957157A CN115957157A (en) | 2023-04-14 |
| CN115957157B true CN115957157B (en) | 2024-02-06 |
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| Country | Link |
|---|---|
| CN (1) | CN115957157B (en) |
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2023
- 2023-02-13 CN CN202310102778.2A patent/CN115957157B/en active Active
Non-Patent Citations (1)
| Title |
|---|
| 超声波在植物有效成分提取中的应用;王铮敏;《三明高等专科学校学报》;第19卷(第4期);45-53 * |
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