CN115956513A - Dog tooth cleaning bone for preventing dental plaque and dental calculus and processing technology thereof - Google Patents
Dog tooth cleaning bone for preventing dental plaque and dental calculus and processing technology thereof Download PDFInfo
- Publication number
- CN115956513A CN115956513A CN202211645684.1A CN202211645684A CN115956513A CN 115956513 A CN115956513 A CN 115956513A CN 202211645684 A CN202211645684 A CN 202211645684A CN 115956513 A CN115956513 A CN 115956513A
- Authority
- CN
- China
- Prior art keywords
- parts
- dental
- bone
- calculus
- canine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 90
- 208000002064 Dental Plaque Diseases 0.000 title claims abstract description 52
- 208000006558 Dental Calculus Diseases 0.000 title claims abstract description 39
- 206010044029 Tooth deposit Diseases 0.000 title claims abstract description 37
- 230000003405 preventing effect Effects 0.000 title claims abstract description 37
- 238000012545 processing Methods 0.000 title claims abstract description 20
- 238000005516 engineering process Methods 0.000 title claims abstract description 13
- 238000004140 cleaning Methods 0.000 title claims description 43
- 240000005002 Erythronium dens canis Species 0.000 title description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 63
- 241000282465 Canis Species 0.000 claims abstract description 47
- 238000001035 drying Methods 0.000 claims abstract description 40
- 239000000843 powder Substances 0.000 claims abstract description 35
- 239000011343 solid material Substances 0.000 claims abstract description 33
- 238000010438 heat treatment Methods 0.000 claims abstract description 29
- 239000011344 liquid material Substances 0.000 claims abstract description 26
- 229920002472 Starch Polymers 0.000 claims abstract description 23
- 239000008107 starch Substances 0.000 claims abstract description 23
- 235000019698 starch Nutrition 0.000 claims abstract description 23
- 235000019482 Palm oil Nutrition 0.000 claims abstract description 21
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 21
- 239000002540 palm oil Substances 0.000 claims abstract description 21
- 241000199919 Phaeophyceae Species 0.000 claims abstract description 20
- 229920001661 Chitosan Polymers 0.000 claims abstract description 19
- 229920002678 cellulose Polymers 0.000 claims abstract description 19
- 239000001913 cellulose Substances 0.000 claims abstract description 19
- 229940027779 persimmon extract Drugs 0.000 claims abstract description 18
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims abstract description 17
- 229960000306 zinc gluconate Drugs 0.000 claims abstract description 17
- 235000011478 zinc gluconate Nutrition 0.000 claims abstract description 17
- 239000011670 zinc gluconate Substances 0.000 claims abstract description 17
- 238000007493 shaping process Methods 0.000 claims abstract description 13
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 claims abstract description 4
- 235000011180 diphosphates Nutrition 0.000 claims abstract description 4
- 229940048084 pyrophosphate Drugs 0.000 claims abstract description 4
- 229940045110 chitosan Drugs 0.000 claims abstract description 3
- 241000282472 Canis lupus familiaris Species 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- 241000287828 Gallus gallus Species 0.000 claims description 17
- 108010010803 Gelatin Proteins 0.000 claims description 16
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 16
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 16
- FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 claims description 16
- 229940107187 fructooligosaccharide Drugs 0.000 claims description 16
- 229920000159 gelatin Polymers 0.000 claims description 16
- 239000008273 gelatin Substances 0.000 claims description 16
- 235000019322 gelatine Nutrition 0.000 claims description 16
- 235000011852 gelatine desserts Nutrition 0.000 claims description 16
- DLRVVLDZNNYCBX-RTPHMHGBSA-N isomaltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-RTPHMHGBSA-N 0.000 claims description 16
- 239000000845 maltitol Substances 0.000 claims description 16
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims description 16
- 229940035436 maltitol Drugs 0.000 claims description 16
- 235000010449 maltitol Nutrition 0.000 claims description 16
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 16
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 16
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 claims description 16
- 229940048086 sodium pyrophosphate Drugs 0.000 claims description 16
- 235000019818 tetrasodium diphosphate Nutrition 0.000 claims description 16
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 claims description 16
- 239000001726 jatropha manihot extract Substances 0.000 claims description 15
- 210000004185 liver Anatomy 0.000 claims description 15
- NEGYEDYHPHMHGK-UHFFFAOYSA-N para-methoxyamphetamine Chemical compound COC1=CC=C(CC(C)N)C=C1 NEGYEDYHPHMHGK-UHFFFAOYSA-N 0.000 claims description 15
- 229940106668 yucca extract Drugs 0.000 claims description 15
- 238000001125 extrusion Methods 0.000 claims description 14
- 229940014259 gelatin Drugs 0.000 claims description 14
- 230000008569 process Effects 0.000 claims description 13
- 238000004519 manufacturing process Methods 0.000 claims description 9
- 210000003464 cuspid Anatomy 0.000 claims description 4
- 238000010924 continuous production Methods 0.000 abstract description 2
- 239000007789 gas Substances 0.000 description 17
- 238000012360 testing method Methods 0.000 description 17
- 241001465754 Metazoa Species 0.000 description 16
- 239000013642 negative control Substances 0.000 description 15
- 230000001603 reducing effect Effects 0.000 description 11
- 239000003039 volatile agent Substances 0.000 description 8
- 230000015572 biosynthetic process Effects 0.000 description 7
- 150000001875 compounds Chemical class 0.000 description 7
- 210000000214 mouth Anatomy 0.000 description 7
- 206010002091 Anaesthesia Diseases 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 6
- 206010006326 Breath odour Diseases 0.000 description 6
- 208000032139 Halitosis Diseases 0.000 description 6
- 230000037005 anaesthesia Effects 0.000 description 6
- 238000007599 discharging Methods 0.000 description 6
- 238000001514 detection method Methods 0.000 description 5
- AYRXSINWFIIFAE-SCLMCMATSA-N Isomaltose Natural products OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@@H](O)[C@@H](O)[C@@H]1O AYRXSINWFIIFAE-SCLMCMATSA-N 0.000 description 4
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 description 4
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 4
- 229940112822 chewing gum Drugs 0.000 description 4
- 235000015218 chewing gum Nutrition 0.000 description 4
- 208000007565 gingivitis Diseases 0.000 description 4
- 208000028169 periodontal disease Diseases 0.000 description 4
- 230000009467 reduction Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000011701 zinc Substances 0.000 description 4
- 229910052725 zinc Inorganic materials 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 230000007505 plaque formation Effects 0.000 description 3
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 2
- 206010039897 Sedation Diseases 0.000 description 2
- 208000008312 Tooth Loss Diseases 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 244000052616 bacterial pathogen Species 0.000 description 2
- 230000003385 bacteriostatic effect Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000001680 brushing effect Effects 0.000 description 2
- 230000035622 drinking Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910000037 hydrogen sulfide Inorganic materials 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 210000001165 lymph node Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000006996 mental state Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 230000036280 sedation Effects 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 230000009747 swallowing Effects 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- HXTQBSFRAGSYBA-UHFFFAOYSA-N 1,3-benzoxazole;hydrochloride Chemical compound [Cl-].C1=CC=C2OC=[NH+]C2=C1 HXTQBSFRAGSYBA-UHFFFAOYSA-N 0.000 description 1
- MCSXGCZMEPXKIW-UHFFFAOYSA-N 3-hydroxy-4-[(4-methyl-2-nitrophenyl)diazenyl]-N-(3-nitrophenyl)naphthalene-2-carboxamide Chemical compound Cc1ccc(N=Nc2c(O)c(cc3ccccc23)C(=O)Nc2cccc(c2)[N+]([O-])=O)c(c1)[N+]([O-])=O MCSXGCZMEPXKIW-UHFFFAOYSA-N 0.000 description 1
- TYJOQICPGZGYDT-UHFFFAOYSA-N 4-methylsulfonylbenzenesulfonyl chloride Chemical compound CS(=O)(=O)C1=CC=C(S(Cl)(=O)=O)C=C1 TYJOQICPGZGYDT-UHFFFAOYSA-N 0.000 description 1
- 241000606749 Aggregatibacter actinomycetemcomitans Species 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 208000018035 Dental disease Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010018275 Gingival atrophy Diseases 0.000 description 1
- 208000034619 Gingival inflammation Diseases 0.000 description 1
- 208000034693 Laceration Diseases 0.000 description 1
- 208000007117 Oral Ulcer Diseases 0.000 description 1
- 208000005888 Periodontal Pocket Diseases 0.000 description 1
- 241000605862 Porphyromonas gingivalis Species 0.000 description 1
- 208000014151 Stomatognathic disease Diseases 0.000 description 1
- 206010042682 Swelling face Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 206010048259 Zinc deficiency Diseases 0.000 description 1
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940124599 anti-inflammatory drug Drugs 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 210000004195 gingiva Anatomy 0.000 description 1
- 201000005562 gingival recession Diseases 0.000 description 1
- 230000036449 good health Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000018984 mastication Effects 0.000 description 1
- 238000010077 mastication Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000009740 moulding (composite fabrication) Methods 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 229940127249 oral antibiotic Drugs 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 210000003254 palate Anatomy 0.000 description 1
- 238000002559 palpation Methods 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 150000003464 sulfur compounds Chemical class 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 229960004175 xylazine hydrochloride Drugs 0.000 description 1
- 229940081836 yucca schidigera extract Drugs 0.000 description 1
Images
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Dental Preparations (AREA)
Abstract
The invention discloses a processing technology of a canine dental bone cleaner for preventing dental plaque calculus, which comprises the following steps: 1) Uniformly mixing solid materials, wherein the solid materials comprise starch, brown algae powder, persimmon extract, pyrophosphate, zinc gluconate, chitosan and cellulose; 2) Adding a liquid material into the uniformly mixed solid material, and uniformly mixing, wherein the liquid material contains hydrogenated palm oil, an emulsifier and glycerol; 3) And heating the uniformly mixed solid material and liquid material in a steam heating mode, shaping, and drying to obtain the canine clean tooth bone. The invention realizes continuous production, prevents the dental plaque from hardening in the shelf life and has obvious dental plaque and dental calculus preventing effect.
Description
Technical Field
The invention belongs to the field of tooth cleaning bones, and particularly relates to a tooth cleaning bone for dogs for preventing dental bacteria plaque dental calculus and a processing technology thereof.
Background
The teeth of the dog are clean and healthy, dental plaque discolors the teeth, and the teeth are accumulated and calcified for a long time to form dental calculus, which can cause gingival inflammation and finally cause tooth loss. Brushing a pet dog's teeth is a challenge to most pet owners and is difficult to adhere to. Going to a veterinary clinic to clean teeth is expensive and requires anesthesia to pets, and many pet owners are concerned about safety issues. Therefore, daily prevention of dental plaque dental calculus and prevention or slowing of growth of dental plaque dental calculus are very necessary.
However, the chew toy made of inedible materials such as rubber and plastic may be broken and swallowed. The animal cortex biting gum has low production efficiency and high price. The starch substrate chewing gum has high production efficiency and low price, the common starch substrate chewing gum is directly formed by extruding starch by a screw, but even if the chewing gum is in a shelf life, the chewing gum becomes harder and harder due to the aging of the starch and finally becomes into a glassy texture. The dogs are easy to hurt the gum in the biting process.
Disclosure of Invention
An object of the present invention is to solve at least the above problems and/or disadvantages and to provide at least the advantages described hereinafter.
Still another object of the present invention is to provide a process for preparing a canine dental bone cleaner for preventing plaque dental calculus,
therefore, the technical scheme provided by the invention is as follows:
a processing technology of canine dental cleaning bone for preventing dental plaque and dental calculus comprises the following steps:
1) Uniformly mixing solid materials, wherein the solid materials comprise starch, brown algae powder, persimmon extract, pyrophosphate, zinc gluconate, chitosan and cellulose;
2) Adding a liquid material into the uniformly mixed solid material, and uniformly mixing, wherein the liquid material contains hydrogenated palm oil, an emulsifier and glycerol;
3) And heating the uniformly mixed solid material and liquid material in a steam heating mode, shaping, and drying to obtain the canine dental bone cleaner.
Preferably, in the process for processing canine dental scaler for preventing dental plaque and calculus, the solid material further comprises: collecting isomaltooligosaccharide, maltitol, fructo-oligosaccharide, gelatin, carnis gallus Domesticus powder, hepar gallus Domesticus hydrolyzed powder, sodium pyrophosphate, sodium carboxymethylcellulose and Yucca Schidigera extract.
Preferably, in the process for processing canine dental cleaning bone for preventing dental plaque and dental calculus, the solid material comprises the following components in parts by weight: 10-60 parts of starch, 10-30 parts of isomaltooligosaccharide, 1-20 parts of maltitol, 1-20 parts of fructo-oligosaccharide, 1-20 parts of gelatin, 1-20 parts of chicken powder, 1-10 parts of cellulose, 1-10 parts of brown algae powder, 1-10 parts of chicken liver hydrolyzed powder, 0.01-1 part of sodium pyrophosphate, 0.01-1 part of zinc gluconate, 0.01-1 part of persimmon extract, 1-10 parts of hydrogenated palm oil, 0.1-1 part of emulsifier, 0.1-1 part of chitosan, 0.01-5 parts of sodium carboxymethylcellulose and 0.01-0.5 part of yucca extract.
Preferably, in the process for processing canine dental bone cleaner for preventing dental plaque and dental calculus, the liquid material further comprises the following components in parts by weight: and (3) water.
Preferably, in the process for processing canine dental scaler for preventing dental plaque and calculus, the liquid material comprises: 1-10 parts of hydrogenated palm oil, 0.1-1 part of emulsifier, 10-30 parts of glycerol and 10-50 parts of water.
Preferably, in the processing technology of the canine dental bone cleaner for preventing dental plaque and dental calculus, the heating temperature is not more than 90 ℃ and the time is not more than 5min.
Preferably, in the process for processing the canine dental bone cleaner for preventing dental plaque and dental calculus, the shaping adopts extrusion molding, no additional heat energy is given except mechanical energy in the extrusion molding, and the discharging temperature is not higher than 80 ℃.
Preferably, in the process for processing canine dental disease bone for preventing dental plaque and dental calculus, the drying step comprises the following steps: firstly drying at the temperature of 55 ℃ for 3h, then drying at the temperature of 65 ℃ for 5h, and finally drying at the temperature of 55 ℃ for 5h, wherein the water content in the canine dental cleaning bone is less than 16 percent after drying.
A dog tooth cleaning bone for preventing dental bacteria plaque and dental calculus is prepared by the processing technology of any one of the dog tooth cleaning bones.
Preferably, in the canine tooth cleaning bone for preventing dental plaque and dental calculus, the canine tooth cleaning bone comprises the following components in parts by weight: 10-60 parts of starch, 10-30 parts of isomaltooligosaccharide, 1-20 parts of maltitol, 1-20 parts of fructo-oligosaccharide, 1-20 parts of gelatin, 1-20 parts of chicken powder, 1-10 parts of cellulose, 1-10 parts of brown algae powder, 1-10 parts of chicken liver hydrolyzed powder, 0.01-1 part of sodium pyrophosphate, 0.01-1 part of zinc gluconate, 0.01-1 part of persimmon extract, 1-10 parts of hydrogenated palm oil, 0.1-1 part of emulsifier, 0.1-1 part of chitosan, 0.01-5 parts of sodium carboxymethylcellulose, 0.01-0.5 part of yucca extract, 1-10 parts of hydrogenated palm oil, 0.1-1 part of emulsifier and 10-30 parts of glycerol.
The invention comprises at least the following advantages:
the canine dental bone cleaner prepared by the invention has the efficacy of relieving dental plaque formation for Beagle dogs after being continuously administered for 14 days and 28 days, has the efficacy of relieving dental calculus formation for 28 days, and has the efficacy of reducing oral gas volatile compounds (H) after being continuously administered for 28 days 2 S+CH 3 SH) concentration, for two reasons: the first is due to the fact that the physical friction is appropriate, because the texture of the product of the invention is hard and has a certain elasticity. Secondly, because the chemical composition of the present invention prevents oral problems. The specific principle is as follows: brown algae powder: eating brown algae helps to reduce plaque, tartar, and calculus. The product has brown algae content of 1% or more, is safe to eat, has high palatability, is easy to absorb, and does not increase gastrointestinal burden. Persimmon extract: has obvious effect on sulfur compounds such as hydrogen sulfide, methyl mercaptan and the like which cause halitosis, and simultaneously inhibits pathogenic bacteria in the oral cavity, thereby inhibiting halitosis from the source. Pyrophosphate: in pyrophosphateOxygen ions having a negative charge can bind to positively charged calcium ions from the solution, inhibiting tartar formation. Zinc ion: zinc can destroy the formation of bacterial plaque and inhibit the growth of bacteria, and zinc acts on the enzyme system of bacteria and has the bacteriostatic action by interfering the metabolism of the bacteria. Another characteristic of zinc is its ability to stay in the oral mucosa and plaque for a longer period of time to maintain bacteriostatic concentrations. Zinc can also promote growth and development of organisms, enhance immunity and help wound healing, and zinc deficiency can also cause oral ulcer. And (3) chitosan: the chitosan has obvious inhibiting effect on two specific pathogenic bacteria of periodontal disease, namely porphyromonas gingivalis and actinobacillus actinomycetemcomitans. Cellulose: the natural material is added to extract cellulose, so that the intestinal tract peristalsis is promoted, and the halitosis caused by constipation is prevented. The components are combined to obtain the canine dental bone cleaner which has excellent dental plaque and dental calculus preventing effect.
The invention is characterized in that the continuous production is realized, the hardening of the product in the shelf life is prevented, and the invention has obvious functions of preventing dental plaque and dental calculus.
Additional advantages, objects, and features of the invention will be set forth in part in the description which follows and in part will become apparent to those having ordinary skill in the art upon examination of the following or may be learned from practice of the invention.
Drawings
FIG. 1 is a graph of the results of a Beagle dog scoring plaque on day 14 after sequential administration to the bones of the canines in one embodiment of the present invention.
FIG. 2 is a graph of the results of a Beagle dog scoring plaque on day 29 of continuous dosing with Jie's bone in one embodiment of the present invention.
FIG. 3 is a graph of the results of a Beagle dog scoring calculus on day 29 after sequential administration to the bones of the canines in accordance with one embodiment of the present invention.
Figure 4 is a graph of the concentration (ppb) of oral gas volatile compounds in Beagle dogs administered continuously to the bones of the human mouth on day 29 in accordance with one embodiment of the present invention.
FIG. 5 is a graph of the concentration of oral gas volatile compounds (ng/10 mL) by Beagle dogs administered continuously to the bones of the canines on day 29 in accordance with one embodiment of the present invention.
Detailed Description
The present invention is further described in detail below with reference to the attached drawings so that those skilled in the art can implement the invention by referring to the description text.
It will be understood that terms such as "having," "including," and "comprising," as used herein, do not preclude the presence or addition of one or more other elements or groups thereof.
It should be noted that the experimental methods described in the following embodiments are all conventional methods unless otherwise specified, and the reagents and materials described therein are commercially available unless otherwise specified.
The invention provides a processing technology of a canine dental bone cleaner for preventing dental plaque calculus, which explores the following aspects and comprises the following steps:
the formula of the tooth cleaning bone comprises: 10-60% of starch, 10-30% of isomaltooligosaccharide, 1-20% of maltitol, 1-20% of fructo-oligosaccharide, 1-20% of gelatin, 1-20% of chicken powder, 1-10% of cellulose, 1-10% of brown algae powder, 1-10% of chicken liver hydrolyzed powder, 0.01-1% of sodium pyrophosphate, 0.01-1% of zinc gluconate, 0.01-1% of persimmon extract, 1-10% of hydrogenated palm oil, 0.1-1% of emulsifier, 0.1-1% of chitosan, 0.01-5% of sodium carboxymethylcellulose, 0.01-0.5% of yucca extract and 10-30% of glycerol.
The tooth cleaning bone process comprises the following steps: mixing solid materials, adding liquid materials, mixing, heating, extruding and forming, drying and packaging. The drying process parameters are as follows: 55 ℃,3h to 65 ℃,5h to 55 ℃ and 5h. The water content after drying is less than 16%.
The heating temperature of the process is not more than 90 ℃ and the time is not more than 5min. The heating mode is as follows: and (4) heating by steam.
The extrusion molding is a molding process, no additional heat energy is provided except mechanical energy, the discharging temperature is not higher than 80 ℃, the proper gelatinization degree of the starch (starch gelatinization is carried out in the heating and extrusion molding processes) is ensured, and aging within the shelf life is prevented.
Example 1
The formula of the canine dental bone cleaner for preventing dental plaque calculus in the embodiment is as follows: by weight, 20% of starch, 29% of isomaltooligosaccharide, 5% of maltitol, 1% of fructo-oligosaccharide, 10% of gelatin, 4% of chicken powder, 2% of cellulose, 4% of brown algae powder, 3% of chicken liver hydrolyzed powder, 0.2% of sodium pyrophosphate, 0.02% of zinc gluconate, 0.5% of persimmon extract, 2% of hydrogenated palm oil, 0.3% of emulsifier, 0.46% of chitosan, 0.5% of sodium carboxymethylcellulose, 0.02% of yucca extract and 18% of glycerol.
The processing technology of the canine dental cleaning bone for preventing dental plaque calculus with the formula comprises the following steps:
1) Uniformly mixing solid materials, wherein the solid materials comprise starch, isomaltose hypgather, maltitol, fructo-oligosaccharide, gelatin, chicken powder, cellulose, brown algae powder, chicken liver hydrolyzed powder, sodium pyrophosphate, zinc gluconate, a persimmon extract, chitosan, sodium carboxymethylcellulose, a yucca extract and glycerol;
2) Adding a liquid material into the uniformly mixed solid material, and uniformly mixing, wherein the liquid material comprises hydrogenated palm oil, an emulsifier, 30% of water and glycerol;
3) And heating the uniformly mixed solid material and liquid material in a steam heating mode, shaping, and drying to obtain the canine dental bone cleaner. In the heating process, the heating temperature is not more than 90 ℃ and the time is not more than 5min. The shaping adopts extrusion molding, no additional heat energy is given except mechanical energy in the extrusion molding, and the discharging temperature is not higher than 80 ℃. The drying comprises the following steps: firstly drying at the temperature of 55 ℃ for 3h, then drying at the temperature of 65 ℃ for 5h, and finally drying at the temperature of 55 ℃ for 5h, wherein the water content in the canine dental cleaning bone is less than 16 percent after drying.
Example 2
The formula of the canine dental bone cleaner for preventing dental plaque calculus in the embodiment is as follows: by weight, 30% of starch, 20% of isomaltooligosaccharide, 5% of maltitol, 1% of fructo-oligosaccharide, 9% of gelatin, 4% of chicken powder, 2% of cellulose, 4% of brown algae powder, 3% of chicken liver hydrolyzed powder, 0.2% of sodium pyrophosphate, 0.02% of zinc gluconate, 0.5% of persimmon extract, 2% of hydrogenated palm oil, 0.3% of emulsifier, 0.46% of chitosan, 0.5% of sodium carboxymethylcellulose, 0.02% of yucca extract and 18% of glycerol.
The processing technology of the canine dental cleaning bone for preventing dental plaque calculus with the formula comprises the following steps:
1) Uniformly mixing solid materials, wherein the solid materials comprise starch, isomaltose hypgather, maltitol, fructo-oligosaccharide, gelatin, chicken powder, cellulose, brown algae powder, chicken liver hydrolyzed powder, sodium pyrophosphate, zinc gluconate, a persimmon extract, chitosan, sodium carboxymethylcellulose, a yucca extract and glycerol;
2) Adding a liquid material into the uniformly mixed solid material, and uniformly mixing, wherein the liquid material comprises hydrogenated palm oil, an emulsifier, 35% of water and glycerol;
3) And heating the uniformly mixed solid material and liquid material in a steam heating mode, shaping, and drying to obtain the canine clean tooth bone. In the heating process, the heating temperature is not more than 90 ℃ and the time is not more than 5min. The shaping adopts extrusion molding, no additional heat energy is given except mechanical energy in the extrusion molding, and the discharging temperature is not higher than 80 ℃. The drying comprises the following steps: firstly drying at the temperature of 55 ℃ for 3h, then drying at the temperature of 65 ℃ for 5h, and finally drying at the temperature of 55 ℃ for 5h, wherein the water content in the canine dental cleaning bone is less than 16 percent after drying.
Example 3
The formula of the canine dental bone cleaner for preventing dental plaque calculus in the embodiment is as follows: by weight, 40% of starch, 10% of isomaltooligosaccharide, 12% of maltitol, 1% of fructo-oligosaccharide, 3% of gelatin, 2% of chicken powder, 2% of cellulose, 4% of brown algae powder, 2% of chicken liver hydrolyzed powder, 0.2% of sodium pyrophosphate, 0.02% of zinc gluconate, 0.5% of persimmon extract, 2% of hydrogenated palm oil, 0.3% of emulsifier, 0.46% of chitosan, 0.5% of sodium carboxymethylcellulose, 0.02% of yucca extract and 20% of glycerol.
The processing technology of the canine dental cleaning bone for preventing dental plaque calculus with the formula comprises the following steps:
1) Uniformly mixing solid materials, wherein the solid materials comprise starch, isomaltose hypgather, maltitol, fructo-oligosaccharide, gelatin, chicken powder, cellulose, brown algae powder, chicken liver hydrolyzed powder, sodium pyrophosphate, zinc gluconate, a persimmon extract, chitosan, sodium carboxymethylcellulose, a yucca extract and glycerol;
2) Adding a liquid material into the solid material after uniform mixing, and uniformly mixing, wherein the liquid material comprises hydrogenated palm oil, an emulsifier, 40% of water and glycerol;
3) And heating the uniformly mixed solid material and liquid material in a steam heating mode, shaping, and drying to obtain the canine dental bone cleaner. In the heating process, the heating temperature is not more than 90 ℃ and the time is not more than 5min. The shaping adopts extrusion molding, no additional heat energy is given except mechanical energy in the extrusion molding, and the discharging temperature is not higher than 80 ℃. The drying comprises the following steps: firstly drying at 55 ℃ for 3h, then drying at 65 ℃ for 5h, and finally drying at 55 ℃ for 5h, wherein the water content in the canine clean tooth bone is less than 16 percent after drying.
Example 4
The formula of the canine dental bone cleaner for preventing dental plaque calculus in the embodiment is as follows: by weight, 60% of starch, 30% of isomaltooligosaccharide, 20% of maltitol, 20% of fructo-oligosaccharide, 20% of gelatin, 20% of chicken powder, 10% of cellulose, 10% of brown algae powder, 10% of chicken liver hydrolyzed powder, 1% of sodium pyrophosphate, 1% of zinc gluconate, 0.01-1% of persimmon extract, 10% of hydrogenated palm oil, 1% of emulsifier, 1% of chitosan, 0.01-5% of sodium carboxymethylcellulose, 0.01-0.5% of yucca extract and 10-30% of glycerol.
The processing technology of the canine dental cleaning bone for preventing dental plaque calculus with the formula comprises the following steps:
1) Uniformly mixing solid materials, wherein the solid materials comprise starch, isomaltose hypgather, maltitol, fructo-oligosaccharide, gelatin, chicken powder, cellulose, brown algae powder, chicken liver hydrolyzed powder, sodium pyrophosphate, zinc gluconate, a persimmon extract, chitosan, sodium carboxymethylcellulose, a yucca extract and glycerol;
2) Adding a liquid material into the uniformly mixed solid material, and uniformly mixing, wherein the liquid material comprises hydrogenated palm oil, an emulsifier, 50% of water and glycerol;
3) And heating the uniformly mixed solid material and liquid material in a steam heating mode, shaping, and drying to obtain the canine clean tooth bone. In the heating process, the heating temperature is not more than 90 ℃ and the time is not more than 5min. The shaping adopts extrusion molding, no additional heat energy is given except mechanical energy in the extrusion molding, and the discharging temperature is not higher than 80 ℃. The drying comprises the following steps: firstly drying at the temperature of 55 ℃ for 3h, then drying at the temperature of 65 ℃ for 5h, and finally drying at the temperature of 55 ℃ for 5h, wherein the water content in the canine dental cleaning bone is less than 16 percent after drying.
Example 5
The formula of the canine dental bone cleaner for preventing dental plaque calculus in the embodiment is as follows: by weight, 30% of starch, 15% of isomaltooligosaccharide, 10% of maltitol, 2% of fructo-oligosaccharide, 5% of gelatin, 4% of chicken powder, 2% of cellulose, 2% of brown algae powder, 2% of chicken liver hydrolyzed powder, 0.01% of sodium pyrophosphate, 0.01% of zinc gluconate, 0.02% of persimmon extract, 2% of hydrogenated palm oil, 0.1% of emulsifier, 0.8% of chitosan, 0.05% of sodium carboxymethylcellulose, 0.01% of yucca extract and 25% of glycerol. Efficacy validation data:
1. test method
1.1 design of the experiment
(1) Group design
Table 1 group design summary
(2) Route of administration, method of administration, dosage, frequency and duration of administration of the test product
(1) The administration route is as follows: the group A and the group B are fed freely. (2) Dose, frequency and duration of administration: negative control group (group a) was not given any test substance; the group (B) is fed with 1 piece of bone for 2 times per day for 28 days.
(3) Pretreatment and/or formulation of test substances and control substances
Clean bone group (group B): the clean bones (LW 2192-02) are packaged individually and formulated as described in example 1, and are applied to the animal on a daily basis.
1.2 test methods
(1) Animal screening and grouping
The test selects 15 Beagle dogs (male and female) which are qualified in oral cavity examination, have no serious periodontal disease (including severe root bifurcation of a plurality of teeth, attachment loss of periodontal pockets is more than or equal to 50 percent, tooth loose index is more than or equal to 2, tooth loss), have no severe gingivitis (spontaneous bleeding or immediate bleeding after contacting with gingiva), have no inflammation of gingiva, ulcer or mucosal laceration, normally bite teeth and have good health condition, and animals do not use systemic or oral antibiotics or anti-inflammatory drugs 7 days before the test. The animal oral examination is divided into an extraoral examination and an intraoral examination, and the extraoral examination comprises the following contents: mandibular lymph nodes, conditions of mastication and swallowing, facial uniformity (no facial swelling, no fistulous tract); the intraoral examination contents include: dental occlusal conditions, periodontal disease (gingivitis, dental calculus, gingival atrophy, tooth loosening), tongue, palate and throat. The selected 15 Beagle dogs are randomly divided into 2 groups including a negative control group (group A), a tooth cleaning bone group (group B) and 5 dogs/group by adopting a random balanced grouping method according to the condition of dental plaque score (coverage area).
(2) Animal administration
Negative control group (group a): the dogs were fed only normally to maintain the feed.
Clean bone group (group B): the maintenance feed is fed to dog normally, 1 piece of dental bone is fed after meal every time, 2 times/day, and the continuous administration is carried out for 28 days
(3) Scoring of dental plaque and calculus
The plaque and calculus scoring tests show that the teeth are respectively: maxilla-I3, C, P3, P4, M1, mandible-C, P3, P4, M1. Each grading operation is carried out under the animal sedation or anesthesia state, the anesthesia or sedation is carried out by using the xylazine hydrochloride injection, the anesthesia dose is 7.5 mg/kg-10 mg/kg, the specific use dose is based on the actual situation, and the supplementary anesthesia dose is not more than 25% of the first anesthesia dose of the animal. After the relevant operations are completed each time, the benzoxazole hydrochloride injection can be injected by intramuscular injection to accelerate the recovery of animals.
Dental plaque scoring: the plaque condition of the test teeth of each dog was counted once each on 14 th and 29 th days after the administration, the test teeth were stained with a plaque disclosing agent and rinsed with pure water, and the plaque of the test teeth was judged to be scored with reference to the quitley-Hein method modified by turesk et al, and photographed and recorded. The plaque scoring criteria were as follows:
a. coverage area: 0 point = no plaque on the tooth surface; 1 minute = scattered plaque at gingival margin of the neck; 2 points = plaque width at the tooth neck not exceeding 1mm;3 points = plaque coverage width over 1mm at the cervical part, but below 1/3 of the tooth surface; 4 points = plaque coverage area between 1/3 and 2/3 of the tooth surface; 5 points = the plaque covered area occupies more than 2/3 of the tooth surface.
b. Thickness: 0 point = no color; 1 point = light, punctate or reddish; 2 points = medium, red; 3 points = severe, deep red.
c. Calculating the dental plaque score: coverage area x thickness, arithmetic mean calculated from test tooth plaque score.
Scoring dental calculus: after counting plaque status of the test teeth of each dog on day 29, calculus scores of the test teeth were measured using a Warrick-Gorrel statistical meter. The specific operation method comprises brushing dental plaque with soft toothbrush, cleaning with pure water, blowing air with syringe to dry tooth surface or slightly dipping with dry sterile gauze to remove residual water, and grading dental calculus. Calculus scoring criteria were as follows:
a. coverage area: 0 point = no calculus on the tooth surface; 1 point = the coverage of dental calculus on the tooth surface is less than 24%; 2-point = the coverage of dental calculus on the tooth surface is 25% -49%; 3 min = the coverage range of dental calculus on the tooth surface is 50% -74%; 4 points = dental calculus coverage > 75% on tooth surface.
b. And (3) calculating dental calculus score: the arithmetic mean was calculated from the test tooth calculus coverage area.
(4) Oral gas volatile compound concentration detection
Halitosis gas (H) of animals treated with Korean Twin Breason II Tangbesson halitosis detector on day 29 after administration 2 S and CH 3 SH) is detected. The specific operation method comprises the following steps: after the dog is calmed or anesthetized, opening the mouth of the dog for 3-5 s, completely closing the lips of the dog for about 30s, then stretching an injector into the oral cavity from the gap between the canine teeth and the premolar teeth under the condition of not completely opening the lips, closing the lips as much as possible, then slowly pulling a piston to extract about 14mL of gas, staying for 3-5 s to allow the gas to be fully exchanged, immediately pulling the injector out to be connected with a Twin Breason II Thangson halitosis detector after sampling is completed, and measuring the concentration of volatile compounds (methyl mercaptan and hydrogen sulfide) in the extracted oral gas. Repeating the detection for 2-5 times per dog, and preferentially selecting the detection values of two times for statistical analysis.
2. Test results
2.1 clinical screening results.
10 Beagle dogs selected in the study have good mental state, normal appetite for drinking, normal tooth occlusion, normal chewing and swallowing, no serious periodontal disease and gingivitis, no swelling of lower jaw lymph nodes in palpation, no antibiotics in 1 week before the test, and basic requirements of the test are met; meanwhile, after teeth of each dog are cleaned and polished, no indicator residue exists on the teeth after the teeth are stained and washed by the plaque indicator.
2.2 clinical observations
During the official test period, no obvious abnormality was found in all the indications such as mental state, appetite for drinking, respiration, behavioral activities, excretion and the like of all the animals in the negative control group (group A) and the tooth cleaning bone group (group B).
(1) In reducing plaque formation
Sequential administration on day 14 (D14): animal dental plaque scores of a negative control group (group A) and a tooth cleaning bone group (group B) are respectively 5.61 +/-1.948 and 5.10 +/-1.650; mean oral plaque scores were reduced by 9.09% in the bone-cleaned group (group B) compared to the negative control group.
Sequential administration to the bone on day 29 (D29): the animal dental plaque scores of the negative control group (group A) and the tooth cleaning bone group (group B) are respectively 9.78 +/-2.931 and 6.10 +/-1.980; compared with a negative control group, the oral dental plaque score mean value of the tooth cleaning bone group (group B) is reduced by 37.63 percent
TABLE 2Beagle dogs consecutively administered plaque scoring results on days 14 and 29 with scaling of the bones
Remarks (Note): plaque score in tables is reported by "Mean ± SD
TABLE 3 successive dosing of Beagle dogs with dental plaque reduction on days 14 and 29
(2) In relieving dental calculus
Sequential administration to the cleaned bones on day 29 (D29): the calculus scores of animals in the negative control group (group A) and the tooth cleaning bone group (group B) are respectively 1.09 +/-0.400 and 0.68 +/-0.390; the mean oral calculus score was reduced by 37.61% in the bone and tooth cleaning group (group B) compared to the negative control group.
TABLE 4 calculus scoring results of Beagle dogs given consecutive and cleaned dental bones on day 29
Remarks (Note): in the table, the calculus score is reported as "Mean ± SD".
TABLE 5 Beagle dog results of efficacy in reducing dental calculus on day 29 following continuous dosing and scaling of the bones
(3) In reducing oral gas volatile compounds (H) 2 S+CH 3 SH) concentration aspect
Sequential administration to the bone on day 29 (D29): the concentration of oral gas volatile compound in animals in the negative control group (group A) and the tooth cleaning bone group (group B) is 48.40 + -41.781 ppb (0.74 + -0.674 ng/10 mL) and 8.90 + -6.777 ppb (0.14 + -0.097 ng/10 mL), respectively, and the concentration mean value of oral gas volatile compound in the tooth cleaning bone group (group B) is reduced by 81.61% (81.08%) compared with that in the negative control group
TABLE 6 detection results of oral cavity gas volatile compound concentration at 29 th day after continuous feeding and tooth cleaning of Beagle
TABLE 7 efficacy results of Beagle dogs on continuous dosing and on day 29 for reducing oral gas volatile compound concentrations
3. Discussion and evaluation of results
3.1 tooth cleaning bone
(1) In alleviating dental plaque formation
The efficacy of the Beagle dogs who continuously administered the bones for cleaning teeth (group B) was 9.09% and 37.63% and higher than 5% on the dental plaque scores on the 14 th and 29 th days, respectively, compared to the negative control group (group a), indicating that Beagle dogs who continuously administered the bones for cleaning teeth had the efficacy of reducing the formation of dental plaque, and were positively correlated with the length of time that the bones were administered.
(2) In relieving dental calculus
The efficacy of the Beagle dogs in the teeth cleaning bone group (group B) for continuously administering to the teeth cleaning bone group (group a) a calculus reduction score of 37.61% and significantly higher than 5% on day 29 compared to the negative control group (group a) indicates that the Beagle dogs have the efficacy of reducing calculus formation when continuously administering to the teeth cleaning bone group.
(3) In reducing oral gas volatile compounds (H) 2 S+CH 3 Concentration aspect of SH)
The oral gas volatile compound concentration reduction efficacy of the Beagle dog in the bone-cleaning group (group B) on day 29 of continuous administration to the bone-cleaning group (81.08%) was 81.61% (significantly higher than 5%) compared to the negative control group (group a), indicating that Beagle dog has the oral gas volatile compound concentration reduction efficacy of continuous administration to the bone-cleaning group. However, the concentration of volatile compounds in the oral cavity of different animals in the same group varies greatly, which is related to the time between the feeding time and the detection time.
19. Conclusion of the experiment
19.1 clean dental bone
(1) The Beagle dog has the efficacy of reducing the formation of dental plaque after being continuously administered for 14 days and 28 days together with the tooth cleaning bone.
(2) Beagle dogs administered to the clean tooth bone for 28 days had the effect of reducing dental calculus formation.
(3) Beagle dog has oral gas volatile compound (H) reducing effect when continuously administered to clean tooth bone for 28 days 2 S+CH 3 SH) concentration.
The number of modules and the processing scale described herein are intended to simplify the description of the invention. Applications, modifications and variations of the present invention will be apparent to those skilled in the art.
While embodiments of the invention have been described above, it is not limited to the applications set forth in the description and the embodiments, which are fully applicable in various fields of endeavor to which the invention pertains, and further modifications may readily be made by those skilled in the art, it being understood that the invention is not limited to the details shown and described herein without departing from the general concept defined by the appended claims and their equivalents.
Claims (10)
1. A processing technology of a canine tooth cleaning bone for preventing dental plaque and dental calculus is characterized by comprising the following steps:
1) Uniformly mixing solid materials, wherein the solid materials comprise starch, brown algae powder, persimmon extract, pyrophosphate, zinc gluconate, chitosan and cellulose;
2) Adding a liquid material into the uniformly mixed solid material, and uniformly mixing, wherein the liquid material contains hydrogenated palm oil, an emulsifier and glycerol;
3) And heating the uniformly mixed solid material and liquid material in a steam heating mode, shaping, and drying to obtain the canine clean tooth bone.
2. The process for preparing a canine dental bone cleaner for preventing dental plaque calculus as set forth in claim 1, wherein said solid material further comprises: collecting isomaltooligosaccharide, maltitol, fructo-oligosaccharide, gelatin, chicken powder, chicken liver hydrolyzed powder, sodium pyrophosphate, sodium carboxymethylcellulose and Yucca extract.
3. The process for preparing a canine dental bone cleaner for preventing dental plaque calculus as claimed in claim 2, wherein the solid material comprises, in parts by weight: 10-60 parts of starch, 10-30 parts of isomaltooligosaccharide, 1-20 parts of maltitol, 1-20 parts of fructo-oligosaccharide, 1-20 parts of gelatin, 1-20 parts of chicken powder, 1-10 parts of cellulose, 1-10 parts of brown algae powder, 1-10 parts of chicken liver hydrolyzed powder, 0.01-1 part of sodium pyrophosphate, 0.01-1 part of zinc gluconate, 0.01-1 part of persimmon extract, 1-10 parts of hydrogenated palm oil, 0.1-1 part of emulsifier, 0.1-1 part of chitosan, 0.01-5 parts of sodium carboxymethylcellulose and 0.01-0.5 part of yucca extract.
4. The process for preparing a canine dental bone cleaner for preventing dental plaque calculus as claimed in claim 1, wherein the liquid material further comprises, in parts by weight: and (3) water.
5. The process of claim 4, wherein the liquid material comprises: 1-10 parts of hydrogenated palm oil, 0.1-1 part of emulsifier, 10-30 parts of glycerol and 10-50 parts of water.
6. The process for preparing a canine dental bone cleaner for preventing dental plaque and dental calculus according to claim 1, wherein said heating is carried out at a temperature of not more than 90 ℃ for a period of not more than 5min.
7. The process for preparing the dental bone for dogs for preventing dental plaque and dental calculus as claimed in claim 1, wherein the shaping is performed by extrusion molding, wherein the extrusion molding is performed at a temperature not higher than 80 ℃ without adding mechanical energy and heat energy.
8. The process for preparing a canine dental bone cleaner for preventing dental plaque calculus as set forth in claim 4, wherein said drying comprises the steps of: firstly drying at the temperature of 55 ℃ for 3h, then drying at the temperature of 65 ℃ for 5h, and finally drying at the temperature of 55 ℃ for 5h, wherein the water content in the canine dental cleaning bone is less than 16 percent after drying.
9. A canine dental bone for preventing dental plaque calculus, wherein the canine dental bone is prepared according to the process of any one of claims 1 to 8.
10. The canine dental bone cleaner for preventing dental plaque calculus according to claim 9, wherein the canine dental bone cleaner comprises, in parts by weight: 10-60 parts of starch, 10-30 parts of isomaltooligosaccharide, 1-20 parts of maltitol, 1-20 parts of fructo-oligosaccharide, 1-20 parts of gelatin, 1-20 parts of chicken powder, 1-10 parts of cellulose, 1-10 parts of brown algae powder, 1-10 parts of chicken liver hydrolyzed powder, 0.01-1 part of sodium pyrophosphate, 0.01-1 part of zinc gluconate, 0.01-1 part of persimmon extract, 1-10 parts of hydrogenated palm oil, 0.1-1 part of emulsifier, 0.1-1 part of chitosan, 0.01-5 parts of sodium carboxymethylcellulose, 0.01-0.5 part of yucca extract, 1-10 parts of hydrogenated palm oil, 0.1-1 part of emulsifier and 10-30 parts of glycerol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211645684.1A CN115956513A (en) | 2022-12-19 | 2022-12-19 | Dog tooth cleaning bone for preventing dental plaque and dental calculus and processing technology thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211645684.1A CN115956513A (en) | 2022-12-19 | 2022-12-19 | Dog tooth cleaning bone for preventing dental plaque and dental calculus and processing technology thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115956513A true CN115956513A (en) | 2023-04-14 |
Family
ID=87362852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211645684.1A Pending CN115956513A (en) | 2022-12-19 | 2022-12-19 | Dog tooth cleaning bone for preventing dental plaque and dental calculus and processing technology thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115956513A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004212510A1 (en) * | 2004-09-14 | 2006-03-30 | Kra-Mar Pet Supplies Pty Ltd | Edible dental chew device for dogs |
| CN102258143A (en) * | 2011-08-09 | 2011-11-30 | 烟台中宠食品有限公司 | Chew pet food and production process thereof |
| US20110290197A1 (en) * | 2010-05-26 | 2011-12-01 | Koo Bon Gill | Pet dental chew |
| CN110150172A (en) * | 2019-06-28 | 2019-08-23 | 苏州弗艾柏生物科技有限公司 | A kind of dog chew and preparation method thereof with oral care coating |
-
2022
- 2022-12-19 CN CN202211645684.1A patent/CN115956513A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004212510A1 (en) * | 2004-09-14 | 2006-03-30 | Kra-Mar Pet Supplies Pty Ltd | Edible dental chew device for dogs |
| US20110290197A1 (en) * | 2010-05-26 | 2011-12-01 | Koo Bon Gill | Pet dental chew |
| CN102258143A (en) * | 2011-08-09 | 2011-11-30 | 烟台中宠食品有限公司 | Chew pet food and production process thereof |
| CN110150172A (en) * | 2019-06-28 | 2019-08-23 | 苏州弗艾柏生物科技有限公司 | A kind of dog chew and preparation method thereof with oral care coating |
Non-Patent Citations (1)
| Title |
|---|
| 舒航等: "猫面部信息素对家猫外出应激行为的影响", 《今日畜牧兽医》, vol. 37, no. 11, 30 November 2021 (2021-11-30), pages 14 - 17 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5340341B2 (en) | Dental gum for pets | |
| Reiter et al. | Feline odontoclastic resorptive lesions: an unsolved enigma in veterinary dentistry | |
| Clarke et al. | Effectiveness of a vegetable dental chew on periodontal disease parameters in toy breed dogs | |
| US9211246B2 (en) | Treatment and prevention of dental pathology in humans and non-human animals | |
| Fitch et al. | Focal palatine erosion associated with dental malocclusion in captive cheetahs | |
| Hennet et al. | Effect of pellet food size and polyphosphates in preventing calculus accumulation in dogs | |
| US20120276024A1 (en) | Composition And Packaging Method For Animal Dental Care | |
| CN1805692A (en) | Pet food composition | |
| Stookey | Soft rawhide reduces calculus formation in dogs | |
| Lobprise et al. | Dental and oral disease in lagomorphs | |
| Southerden | Review of feline oral disease: 1. Periodontitis and chronic gingivostomatitis | |
| CN115956513A (en) | Dog tooth cleaning bone for preventing dental plaque and dental calculus and processing technology thereof | |
| Dumonceaux | Digestive system | |
| Clarke et al. | Effect of kibble size, shape, and additives on plaque in cats | |
| Wenker et al. | Dental health status and endodontic treatment of captive brown bears (Ursus arctos ssp.) living in the Bernese bear pit | |
| Crowder et al. | Full Study: Evaluation of Efficacy of Reduction of Calculus, Plaque, Gingivitis and Malodor of a Daily Honeycomb Shaped Dental Chew in Dogs | |
| WO2004010962A1 (en) | Liquid composition for protecting oral cavities and teeth of pet animals and use thereof in plaything for pet animals | |
| Grosso–Cuiabá | Occurrence of oral diseases in neotropical wild carnivores kept in captivity at the zoo from Federal University of Mato Grosso–Cuiabá Ocorrência de afecções orais em carnívoros selvagens neotropicais mantidos em cativeiro no zoológico da Universidade Federal de | |
| JP2011079779A (en) | Chewing material for dental care | |
| Scherl et al. | Application of the gingival contour plaque index: six-month plaque and gingivitis study | |
| Hietakangas | Homecare in prevention of periodontal disease in dogs and cats: owner awareness and attitudes | |
| Fagan et al. | Dental malocclusion in a coarse-haired wombat (Vombatus ursinus) | |
| Bellows et al. | Clinical Effectiveness of Sodium Hexametaphosphate in the Important Role of Canine Calculus Reduction | |
| Gualberto et al. | Evaluation of the prophylactic action of veterinary dental gel containing Aloe vera and green tea on calculus formation in dogs submitted to periodontal treatment | |
| WO2023102458A1 (en) | Edible chew and methods of using the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |