CN115931503B - Simple liquefying agent and liquefying device for sputum specimen - Google Patents
Simple liquefying agent and liquefying device for sputum specimen Download PDFInfo
- Publication number
- CN115931503B CN115931503B CN202211647226.1A CN202211647226A CN115931503B CN 115931503 B CN115931503 B CN 115931503B CN 202211647226 A CN202211647226 A CN 202211647226A CN 115931503 B CN115931503 B CN 115931503B
- Authority
- CN
- China
- Prior art keywords
- sputum
- liquefying
- needle
- liquid storage
- storage box
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 206010036790 Productive cough Diseases 0.000 title claims abstract description 68
- 210000003802 sputum Anatomy 0.000 title claims abstract description 68
- 208000024794 sputum Diseases 0.000 title claims abstract description 68
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 26
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 10
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 claims abstract description 9
- 108010067770 Endopeptidase K Proteins 0.000 claims abstract description 8
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims abstract description 5
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims abstract description 5
- 235000019796 monopotassium phosphate Nutrition 0.000 claims abstract description 5
- 239000011780 sodium chloride Substances 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 5
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 claims abstract description 4
- LWIHDJKSTIGBAC-UHFFFAOYSA-K potassium phosphate Substances [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims abstract description 4
- 239000007788 liquid Substances 0.000 claims description 34
- 238000009434 installation Methods 0.000 claims description 17
- 238000009423 ventilation Methods 0.000 claims description 7
- 230000006835 compression Effects 0.000 claims description 5
- 238000007906 compression Methods 0.000 claims description 5
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 claims description 3
- 238000007599 discharging Methods 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 claims 1
- 208000026435 phlegm Diseases 0.000 claims 1
- 210000003097 mucus Anatomy 0.000 description 6
- 238000001514 detection method Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000008055 phosphate buffer solution Substances 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 208000023504 respiratory system disease Diseases 0.000 description 2
- 241000186359 Mycobacterium Species 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 1
- 235000019833 protease Nutrition 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses a simple liquefying agent and a liquefying device for a sputum specimen, which belong to the technical field of medical treatment, wherein the liquefying agent comprises the following components: 0.65 to 0.85 part of dithiothreitol, 0.15 to 0.35 part of proteinase K,0.005 to 0.025 part of monopotassium phosphate, 0.08 to 0.1 part of disodium hydrogen phosphate, 0.5 to 0.7 part of sodium chloride and 4 to 6 parts of water. Therefore, the sample can be conveniently reserved for the patient, the pretreatment steps of laboratory staff are reduced, and the liquefaction purity is improved.
Description
Technical Field
The invention relates to a liquefying agent and a liquefying device, in particular to a simple liquefying agent and a liquefying device for sputum specimens, and belongs to the technical field of medical treatment.
Background
Sputum specimens are commonly used specimens for clinical diagnosis of respiratory diseases, particularly molecular detection specimens for mycobacterium culture and respiratory disease diagnosis, and are convenient to collect and noninvasive compared with alveolar lavage fluid specimens, but a conventional liquefaction method in a clinical laboratory uses 4% sodium hydroxide, so that the liquefaction time is long, the steps are complicated, the purity is low, and sodium hydroxide residues have an inhibition effect on later molecular detection and influence on detection results.
Disclosure of Invention
The invention aims to solve the technical problem of providing a simple liquefying agent and a liquefying device for sputum specimens, which can facilitate a patient to leave specimens, reduce the preliminary treatment steps of laboratory staff and improve the liquefying purity.
In order to solve the problems, the following technical scheme is provided:
designing a simple liquefying agent for sputum specimens, wherein the liquefying agent comprises the following components: 0.65 to 0.85 part of dithiothreitol, 0.15 to 0.35 part of proteinase K,0.005 to 0.025 part of monopotassium phosphate, 0.08 to 0.1 part of disodium hydrogen phosphate, 0.5 to 0.7 part of sodium chloride and 4 to 6 parts of water.
The simple liquefying device for the sputum specimen comprises a liquid storage box for storing simple liquefying agent for the sputum specimen, wherein a detachable sputum reserving and taking cup is connected below the liquid storage box, and a first film for preventing the simple liquefying agent for the sputum specimen from entering the sputum reserving and taking cup and a puncturing assembly for puncturing the first film are arranged in the liquid storage box.
Furthermore, the bottom of the liquid storage box is of a conical structure, and a connecting pipe I is fixedly arranged at the bottom of the liquid storage box.
Furthermore, a second connecting pipe is fixedly arranged at the top of the sputum reserving cup, and the second connecting pipe is connected with the first connecting pipe.
Further, a liquid outlet pipe for discharging the liquefied sputum specimen is fixedly arranged at the bottom of the sputum reserving and taking cup, and a valve is arranged on the liquid outlet pipe.
Further, the puncture assembly comprises a box cover arranged at the top of the liquid storage box, a needle-shaped rod I is sleeved in the middle of the box cover, the tip end of the needle-shaped rod I extends to the inside of the liquid storage box, and a pressing plate is fixedly arranged above the box cover at the extending position of the top end of the needle-shaped rod I.
Further, the peripheral surface of the needle-shaped rod I is rotationally connected with a connecting ring, and a compression spring is fixedly arranged between the upper surface of the connecting ring and the lower surface of the box cover.
Further, at least one bleeder vent has been seted up to the upper surface of lid, the inner wall of bleeder vent is fixed to be provided with film two, the lower surface fixed of clamp plate is provided with the needle-shaped pole two that is used for piercing film two, and needle-shaped pole two cup joints the guide cylinder, and the guide cylinder is located the bleeder vent and just above and the guide cylinder is connected with the lid.
Further, the upper surface of lid is provided with two and encloses the installation strip of loop shape, and two installation strips all cup joint on needle pole one and be the upper and lower setting, and the one end of installation strip is all fixed to be provided with the grafting piece, and the grafting groove corresponding with the grafting piece has all been seted up to the other end of installation strip, two fixedly between the installation strip be provided with a plurality of backup pads, the opening has all been seted up at the middle part of backup pad.
Further, the first film and the second film are tin films.
Compared with the prior art, the invention has the beneficial effects that:
1. by reducing mucus disulfide bond effect by using dithiothreitol, liquefying mucus, decomposing protein by using proteinase K phosphate buffer solution, rapidly reducing mucus in sputum specimen, doubly accelerating liquefaction process of sputum specimen by combining dithiothreitol and proteinase K, improving liquefaction efficiency and purification rate, maintaining stable reaction system for subsequent detection by adjusting PH value by using phosphate buffer solution, reducing influencing factors
2. Through liquid storage box, sputum are stayed and are got cup and puncture the subassembly, be convenient for the patient to stay the sputum sample and get, also need not add the liquefaction agent again simultaneously, medical personnel can pour into the liquefaction agent into the sputum through puncture the subassembly and stay and get the cup in, reduce laboratory personnel's preliminary treatment step, improve liquefaction purity
3. Through setting up the valve, can be convenient for discharge after the complete liquefaction of sputum sample, convenient and fast need not to stay the sputum again and get the cup and demolish.
Drawings
The accompanying drawings are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate the invention and together with the embodiments of the invention, serve to explain the invention. In the drawings:
FIG. 1 is a perspective view of a preferred embodiment of a simple sputum specimen liquefying apparatus in accordance with the present invention
FIG. 2 is a cross-sectional view of a preferred embodiment of a simple sputum specimen liquefying apparatus in accordance with the present invention
FIG. 3 is a split view of a cartridge and lancing assembly of a preferred embodiment of a simple sputum specimen liquefaction apparatus according to the present invention
FIG. 4 is a front view of a mounting bar of a simple sputum specimen liquefying apparatus in accordance with a preferred embodiment of the present invention
Fig. 5 is a front view of a sputum trap cup of a preferred embodiment of a simple sputum specimen liquefying apparatus in accordance with the present invention.
In the figure: 1. a liquid storage box; 2. a box cover; 3. a first connecting pipe; 4. a valve; 5. film I; 6. a needle-shaped rod I; 7. a pressing plate; 8. a connecting ring; 9. a compression spring; 10. ventilation holes; 11. a second film; 12. a needle-shaped rod II; 13. a guide cylinder; 14. a mounting bar; 15. a plug block; 16. a support plate; 17. a notch; 18. positioning the cover; 19. a second connecting pipe; 20. the sputum is left in the cup; 21. and a liquid outlet pipe.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The simple liquefying agent for the sputum specimen provided by the embodiment comprises the following components: 0.65 to 0.85 part of dithiothreitol, 0.15 to 0.35 part of proteinase K,0.005 to 0.025 part of monopotassium phosphate, 0.08 to 0.1 part of disodium hydrogen phosphate, 0.5 to 0.7 part of sodium chloride and 4 to 6 parts of water.
In this embodiment, the liquefying agent includes dithiothreitol 0.75 parts, proteinase K0.25 parts, potassium dihydrogen phosphate 0.015 parts, disodium hydrogen phosphate 0.09 parts, sodium chloride 0.6 parts, and water 5 parts, and by reducing mucus disulfide bond by dithiothreitol, liquefying mucus, proteinase K phosphate buffer solution to decompose protein, rapidly reduce mucus in sputum specimen, and double acceleration of liquefaction process of sputum specimen by combining dithiothreitol and proteinase K, improving liquefaction efficiency and purification rate, and phosphate buffer solution adjusting pH value maintains a stable reaction system for subsequent detection, thereby reducing influencing factors.
As shown in fig. 1-5, a simple and easy liquefying device for a sputum specimen includes a liquid storage box 1 for storing simple liquefying agent for the sputum specimen, a detachable sputum reserving and taking cup 20 is connected below the liquid storage box 1, a first film 5 for preventing the simple liquefying agent for the sputum specimen from entering the sputum reserving and taking cup 20 and a puncturing assembly for puncturing the first film 5 are arranged in the liquid storage box 1, in this embodiment, in order to facilitate the collection of the sputum by a patient, a conical cover is arranged at the top of the sputum reserving and taking cup 20, the phenomenon that the collection is difficult due to the small opening of the sputum reserving and taking cup 20 can be effectively avoided when the sputum is collected, the sputum reserving and taking cup 20 is detached in a rotating mode by the patient, then the sputum is collected into the sputum reserving and taking cup 20, then the sputum reserving and taking cup 20 is reset, a medical staff mixes the liquefying agent in the liquid storage box 1 with the sputum reserving and taking cup 20 through using a puncturing assembly, and then shakes and mixes for 15 minutes, and the like, and after the sputum reserving and taking cup is completely and taking the sputum reserving at the lower place.
The bottom of the liquid storage box 1 is of a conical structure, and a connecting pipe I3 is fixedly arranged at the bottom of the liquid storage box 1.
The top of the sputum reserving cup 20 is fixedly provided with a second connecting pipe 19, the second connecting pipe 19 is connected with a first connecting pipe 3, and the second connecting pipe 19 is connected with the first connecting pipe 3 in a threaded or spliced mode.
In this embodiment, the second connecting pipe 19 is in threaded connection with the first connecting pipe 3, so that the sputum reserving and taking cup 20 can be quickly detached.
The bottom of the sputum reserving and taking cup 20 is fixedly provided with a liquid outlet pipe 21 for discharging liquid of the liquefied sputum specimen, the liquid outlet pipe 21 is provided with a valve 4, and medical staff can collect the completely liquefied sputum specimen conveniently by arranging the valve 4.
The puncture assembly comprises a box cover 2 arranged at the top of a liquid storage box 1, the box cover 2 and the liquid storage box 1 can be in an integral structure or in a split threaded connection, a needle-shaped rod I6 is sleeved in the middle of the box cover 2, the tip of the needle-shaped rod I6 extends to the inside of the liquid storage box 1, a pressing plate 7 is fixedly arranged above the box cover 2 at the top end of the needle-shaped rod I6, medical staff downwards moves the needle-shaped rod I6 until a film I5 is punctured by the pressing plate 7, a liquefying agent in the liquid storage box 1 flows into a sputum reserving cup 20 through a connecting pipe I3, in this embodiment, in order to ensure the sealing effect on the liquefying agent, a soft seal is adopted between the needle-shaped rod I6 and the box cover 2, and in order to accelerate the outflow speed of the liquefying agent, and a cross blade is arranged at the bottom end of the needle-shaped rod I6.
The peripheral surface of the needle-shaped rod I6 is rotationally connected with a connecting ring 8, a compression spring 9 is fixedly arranged between the upper surface of the connecting ring 8 and the lower surface of the box cover 2, and when the pressing plate 7 is not pressed down, the needle-shaped rod I6 is positioned above the film I5 under the elastic force of the compression spring 9.
At least one ventilation hole 10 is formed in the upper surface of the box cover 2, a film II 11 is fixedly arranged on the inner wall of the ventilation hole 10, a needle-shaped rod II 12 for puncturing the film II 11 is fixedly arranged on the lower surface of the pressing plate 7, a guide cylinder 13 is sleeved on the needle-shaped rod II 12, the guide cylinder 13 is positioned right above the ventilation hole 10 and is connected with the box cover 2, in order to avoid the phenomenon that a liquefying agent cannot fall after puncturing the film I5, the needle-shaped rod II 12 moves downwards along with the pressing plate 7, the film II 11 is punctured in the space formed by the guide cylinder 13 under the guide direction of the guide cylinder, so that air can circulate, and the falling speed of the liquefying agent is conveniently accelerated.
The upper surface of lid 2 is provided with two and encloses into the installation strip 14 of loop shape, two installation strips 14 all cup joint on needle bar one 6 and be the upper and lower setting, the one end of installation strip 14 is all fixed to be provided with grafting piece 15, the grafting groove corresponding with grafting piece 15 has all been seted up to the other end of installation strip 14, fixedly be provided with a plurality of backup pads 16 between two installation strips 14, opening 17 has all been seted up at the middle part of backup pad 16, when needs transport liquefying plant, carry out the completion to two installation strips 14, make two installation strips 14 form annular structure under grafting piece 15 and grafting groove's effect, can provide reaction force to clamp plate 7 under the effect of backup pad 16, can avoid leading to needle bar one 6 to puncture film one 5's phenomenon because of collision in the in-process to liquefying plant carries out the transportation.
The first film 5 and the second film 11 are tin films, are not easy to oxidize, and can prolong the service life of the liquefying agent.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the invention.
Claims (7)
1. The simple liquefying device for the sputum specimen is characterized by comprising a liquid storage box (1) for storing a simple liquefying agent for the sputum specimen, wherein the simple liquefying agent for the sputum specimen comprises the following components: 0.65-0.85 part of dithiothreitol, 0.15-0.35 part of proteinase K, 0.005-0.025 part of monopotassium phosphate, 0.08-0.1 part of disodium hydrogen phosphate, 0.5-0.7 part of sodium chloride and 4-6 parts of water, wherein a detachable sputum reserving cup (20) is connected below the liquid storage box (1), and a film I (5) for preventing the simple liquefying agent of the sputum specimen from entering the sputum reserving cup (20) and a puncturing component for puncturing the film I (5) are arranged in the liquid storage box (1);
the puncture assembly comprises a box cover (2) arranged at the top of the liquid storage box (1), a needle-shaped rod I (6) is sleeved at the middle part of the box cover (2), the tip end of the needle-shaped rod I (6) extends to the inside of the liquid storage box (1), and a pressing plate (7) is fixedly arranged above the box cover (2) at the top end of the needle-shaped rod I (6);
at least one ventilation hole (10) is formed in the upper surface of the box cover (2), a second film (11) is fixedly arranged on the inner wall of the ventilation hole (10), a second needle-shaped rod (12) for puncturing the second film (11) is fixedly arranged on the lower surface of the pressing plate (7), a guide cylinder (13) is sleeved on the second needle-shaped rod (12), and the guide cylinder (13) is located right above the ventilation hole (10) and is connected with the box cover (2).
2. The simple liquefying device for sputum specimens according to claim 1, wherein the bottom of the liquid storage box (1) is of a conical structure, and a connecting pipe I (3) is fixedly arranged at the bottom of the liquid storage box (1).
3. The simple and easy liquefying device of a sputum specimen according to claim 2, wherein a second connecting pipe (19) is fixedly arranged at the top of the sputum reserving cup (20), and the second connecting pipe (19) is connected with the first connecting pipe (3).
4. The simple and easy liquefying device of a sputum specimen according to claim 1, wherein a liquid outlet pipe (21) for discharging the liquefied sputum specimen is fixedly arranged at the bottom of the sputum reserving cup (20), and a valve (4) is arranged on the liquid outlet pipe (21).
5. The simple and easy liquefying device of a sputum specimen according to claim 1, wherein the peripheral surface of the needle-shaped rod I (6) is rotatably connected with a connecting ring (8), and a compression spring (9) is fixedly arranged between the upper surface of the connecting ring (8) and the lower surface of the box cover (2).
6. The simple and easy liquefying device of phlegm sample according to claim 1, characterized in that, the upper surface of lid (2) is provided with two and encloses into annular installation strip (14), and two installation strip (14) all cup joint on needle pole one (6) and are setting up from top to bottom, and the grafting piece (15) is all fixed to be provided with in one end of installation strip (14), and the grafting groove corresponding with grafting piece (15) is all seted up to the other end of installation strip (14), two fixedly between installation strip (14) be provided with a plurality of backup pads (16), opening (17) are all seted up at the middle part of backup pad (16).
7. The simple liquefying device for sputum specimens according to claim 1, wherein the first film (5) and the second film (11) are tin films.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211647226.1A CN115931503B (en) | 2022-12-21 | 2022-12-21 | Simple liquefying agent and liquefying device for sputum specimen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211647226.1A CN115931503B (en) | 2022-12-21 | 2022-12-21 | Simple liquefying agent and liquefying device for sputum specimen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115931503A CN115931503A (en) | 2023-04-07 |
| CN115931503B true CN115931503B (en) | 2023-12-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211647226.1A Active CN115931503B (en) | 2022-12-21 | 2022-12-21 | Simple liquefying agent and liquefying device for sputum specimen |
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| CN (1) | CN115931503B (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103994909A (en) * | 2014-06-09 | 2014-08-20 | 上海微银生物技术有限公司 | Phlegm tank |
| CN204618909U (en) * | 2015-01-27 | 2015-09-09 | 海门市优耐特实验器材发展有限公司 | A kind of phlegm liquit collector |
| CN204846848U (en) * | 2015-07-27 | 2015-12-09 | 北京慕加投资有限公司 | Oral administration liquid bottle |
| CN204882189U (en) * | 2015-08-24 | 2015-12-16 | 郑州点石生物技术有限公司 | Phlegm digestion cup |
| WO2016107011A1 (en) * | 2014-12-31 | 2016-07-07 | 上海市肺科医院 | Sputum collecting device |
| CN113956979A (en) * | 2020-07-20 | 2022-01-21 | 袁梁 | Clinical sputum specimen liquefaction treatment method |
| CN216207777U (en) * | 2021-10-09 | 2022-04-05 | 上海康黎诊断技术有限公司 | Sputum sample collecting tube |
-
2022
- 2022-12-21 CN CN202211647226.1A patent/CN115931503B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103994909A (en) * | 2014-06-09 | 2014-08-20 | 上海微银生物技术有限公司 | Phlegm tank |
| WO2016107011A1 (en) * | 2014-12-31 | 2016-07-07 | 上海市肺科医院 | Sputum collecting device |
| CN204618909U (en) * | 2015-01-27 | 2015-09-09 | 海门市优耐特实验器材发展有限公司 | A kind of phlegm liquit collector |
| CN204846848U (en) * | 2015-07-27 | 2015-12-09 | 北京慕加投资有限公司 | Oral administration liquid bottle |
| CN204882189U (en) * | 2015-08-24 | 2015-12-16 | 郑州点石生物技术有限公司 | Phlegm digestion cup |
| CN113956979A (en) * | 2020-07-20 | 2022-01-21 | 袁梁 | Clinical sputum specimen liquefaction treatment method |
| CN216207777U (en) * | 2021-10-09 | 2022-04-05 | 上海康黎诊断技术有限公司 | Sputum sample collecting tube |
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| Publication number | Publication date |
|---|---|
| CN115931503A (en) | 2023-04-07 |
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