CN115892715A

CN115892715A - Detection kit

Info

Publication number: CN115892715A
Application number: CN202211589199.7A
Authority: CN
Inventors: 宁平; 徐艳艳; 赵建华; 王硕硕; 赵国强; 孙谧
Original assignee: Qingdao Ruisikeer Biotechnology Co ltd
Current assignee: Qingdao Ruisikeer Biotechnology Co ltd
Priority date: 2022-12-12
Filing date: 2022-12-12
Publication date: 2023-04-04

Abstract

The invention provides a detection kit, which belongs to the technical field of medical consumables and comprises a kit body and a drainage assembly, wherein the kit body comprises a body, a reagent card and an injector, the body comprises a storage cavity and a first accommodating cavity which are sequentially arranged from left to right, and a second accommodating cavity and a third accommodating cavity which are sequentially arranged from top to bottom; the first accommodating cavity is communicated with the second accommodating cavity; the reagent card is placed in the second containing cavity, and the injector is placed in the third containing cavity; the storage cavity is used for storing diluent, and the reagent card comprises a sample adding area; through arranging the reagent card in the second holds the chamber for reagent card and detection sample are difficult to be contaminated, can guarantee better detection accuracy. And meanwhile, the sample adding area is matched with the stepped channel for use, so that the stepped channel has a guiding function on the injector and ensures that the injector can be aligned with the sample adding area.

Description

Detection kit

Technical Field

The invention belongs to the technical field of medical consumables, and particularly relates to a detection kit.

Background

In Vitro Diagnosis, i.e., IVD (In Vitro Diagnosis), refers to products and services for determining diseases or body functions by detecting human body samples (blood, body fluids, tissues, etc.) In addition to the human body to obtain clinical Diagnosis information. Generally, the consumables and the devices required for the in vitro diagnostic process require the professional to operate in a special laboratory or medical institution, which is expensive and takes a long time to wait for the analysis.

At present, in the use process of the detection kit, the reagent card and the diluent are generally taken out, the sample is added to the reagent card through a pipette and the diluent is injected into the reagent card, and then the result is displayed by waiting for the reagent card. However, the reagent card is usually placed on a table, and the tester will spot the card with some care, which may reduce the accuracy of the test of the card and may render the card useless.

Disclosure of Invention

The embodiment of the invention provides a detection kit, and aims to solve the problem that a reagent card of an existing detection kit is easily contaminated carelessly.

In view of the above problems, the technical solution proposed by the present invention is:

the invention provides a detection kit, comprising:

the reagent card comprises a box body, a reagent card and an injector, wherein the box body comprises a storage cavity and a first accommodating cavity which are sequentially arranged from left to right, and a second accommodating cavity and a third accommodating cavity which are sequentially arranged from top to bottom; the first accommodating cavity is communicated with the second accommodating cavity; the reagent card is placed in the second containing cavity, and the injector is placed in the third containing cavity;

the storage cavity is used for storing diluent, and the reagent card comprises a sample adding area;

a flow directing assembly including a housing embedded within the first receiving cavity, the housing having a stepped passageway therethrough along an axis;

wherein the first containing cavity is configured to correspond to the sample addition region in position, so that the stepped channel corresponds to the sample addition region in position.

As a preferable technical scheme of the invention, a cover plate is arranged in the storage cavity, and an integrally formed arc-shaped bulge is arranged on the cover plate.

As a preferred technical scheme of the present invention, an observation hole communicated with the second accommodating chamber is disposed on one side of the first accommodating chamber, and a magnifying lens is embedded in the observation hole;

wherein the reagent card further comprises a display area, the position of the viewing aperture being configured to correspond to the display area.

As a preferable technical solution of the present invention, the body is provided with a first chute which opens upward, and the first chute is provided with a freely slidable plugging cover therein.

As a preferred technical scheme of the invention, the stepped channel comprises an adapter hole and a drainage hole which are sequentially arranged from top to bottom, and the adapter hole is communicated with the drainage hole;

wherein the bore diameter of the fitting hole is configured to be larger than the bore diameter of an empty barrel of the syringe.

In a preferred embodiment of the present invention, an interlayer is disposed in the housing, and the housing is covered with a sealing cover, and an end of the sealing cover extends into the interlayer.

As a preferred technical solution of the present invention, the reagent card further comprises a squeezing springback assembly, wherein the squeezing springback assembly is disposed between the side wall of the second accommodating cavity and the reagent card; the extrusion resilience assembly comprises a bottom plate, a push plate and an extrusion resilience part, two opposite telescopic pieces are arranged between the push plate and the bottom plate, a fourth accommodating cavity is formed in the bottom plate, and the extrusion resilience part is arranged in the fourth accommodating cavity;

wherein the press resilience portion is configured to restrict a position of the push plate when the push plate is subjected to a force.

As a preferable technical solution of the present invention, the extrusion springback portion includes a moving plate, a push rod and a connecting plate, two opposite linear sliding plates are disposed in the fourth accommodating cavity, a linear sliding groove adapted to the linear sliding plates is disposed on one side of the moving plate opposite to the two linear sliding plates, a moving hole is disposed on one side of the moving plate opposite to the push plate, the push rod penetrates through the moving hole, so that one end of the push rod is fixed to the moving plate, the other end of the push rod is fixed to the push plate, a polygonal sliding groove is disposed on the moving plate, a rotating shaft and a sliding rod are respectively fixed to two ends of the connecting plate, the rotating shaft is rotatably connected to the bottom plate, and the sliding rod and the polygonal sliding groove can be freely slidably connected.

As a preferable technical solution of the present invention, the pressing resilient part further includes an elastic member, and the elastic member is disposed between the side wall of the fourth accommodating chamber and the moving plate.

As a preferred technical solution of the present invention, the polygonal sliding chute includes a first side wall, a second side wall, and a third side wall; wherein an inclination angle of the first sidewall is configured to be greater than an inclination angle of the second sidewall, and the third sidewall is configured to form a non-parallel arrangement with an opposite sidewall.

Compared with the prior art, the invention has the beneficial effects that:

(1) Through placing the reagent card in the second holds the chamber for reagent card and detection sample are difficult for being contaminated, can guarantee better detection accuracy. Meanwhile, the sample adding area is matched with the step channel for use, so that the step channel plays a guiding role on the injector, and the injector can be ensured to be aligned to the sample adding area.

(2) Through the matching between the push plate and the extrusion springback part, on one hand, the assembly is convenient during production; on the other hand, when the tester cannot effectively inject the detection sample or the diluent into the sample application area, the reagent card can be taken out, thereby providing various choices for the tester.

The above description is only an overview of the technical solutions of the present invention, and the present invention can be implemented in accordance with the content of the description so as to make the technical means of the present invention more clearly understood, and the above and other objects, features, and advantages of the present invention will be more clearly understood.

Drawings

FIG. 1 is a perspective view of a detection kit disclosed in the present invention;

FIG. 2 is a sectional elevation view from a first perspective of FIG. 1;

FIG. 3 is an elevation cross-sectional view of the second view of FIG. 1;

FIG. 4 is a schematic structural diagram of a reagent card of the detection kit disclosed in the present invention;

FIG. 5 is a perspective view of a drainage assembly of an assay kit as disclosed herein;

FIG. 6 is a sectional elevation view of a drainage assembly of a test kit as disclosed herein;

FIG. 7 is a perspective view of a tamper-evident assembly of the disclosed test kit;

FIG. 8 is an exploded view of the tamper-evident component of the disclosed test kit;

FIG. 9 is a top view of a movable plate of the detection kit disclosed in the present invention;

FIG. 10 is a flow chart of a method of using the disclosed assay kit.

Description of reference numerals: 100. a box body; 110. a body; 111. a storage chamber; 1111. a cover plate; 1112. an arc-shaped bulge; 112. a first accommodating chamber; 113. a second accommodating chamber; 114. a third accommodating chamber; 115. an observation hole; 1151. a magnifying lens; 116. a first chute; 120. a reagent card; 121. a sample adding area; 122. a display area; 123. a second chute; 130. an injector; 140. a blocking cover; 200. a drainage assembly; 210. a housing; 211. a stepped passageway; 2111. an adapter hole; 2112. a drainage hole; 212. an interlayer; 220. a sealing cover; 221. a linear protrusion; 300. squeezing the rebound assembly; 310. a base plate; 311. a fourth accommodating chamber; 3111. a linear slide plate; 3112. moving the hole; 3113. a first positioning post; 320. pushing the plate; 321. a telescoping member; 330. extruding the rebound part; 331. moving the plate; 3311. a polygonal chute; 33111. a first side wall; 33112. a second side wall; 33113. a third side wall; 3312. a linear chute; 3313. a second positioning column; 332. a push rod; 333. a connecting plate; 3331. a rotating shaft; 3332. a slide bar; 334. an elastic member.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings of the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be obtained by a person skilled in the art without inventive efforts based on the embodiments of the present invention, are within the scope of protection of the present invention.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined or explained in subsequent figures.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the equipment or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.

Examples

Referring to the attached drawings 1-9, the invention provides a technical scheme: a detection kit comprises a kit body 100 and a drainage assembly 200, wherein the kit body 100 comprises a body 110, a reagent card 120 and an injector 130, the body 110 comprises a storage cavity 111 and a first accommodating cavity 112 which are sequentially arranged from left to right, and a second accommodating cavity 113 and a third accommodating cavity 114 which are sequentially arranged from top to bottom; the first accommodating chamber 112 is communicated with the second accommodating chamber 113; the reagent card 120 is placed in the second receiving chamber 113, and the syringe 130 is placed in the third receiving chamber 114; wherein, the storage cavity 111 is used for storing diluent, and the reagent card 120 comprises a sample adding area 121; the drainage assembly 200 includes a housing 210, the housing 210 being inserted into the first accommodation chamber 112, the housing 210 having a stepped passage 211 passing therethrough along an axis; wherein the first containing chamber 112 is configured to correspond to the sample addition region 121, so that the stepped channel 211 corresponds to the sample addition region 121.

Specifically, by placing the reagent card 120 in the second accommodating cavity 113, the reagent card 120 and the detection sample are not easily contaminated, and better detection accuracy can be ensured. Meanwhile, the sample application region 121 is used in cooperation with the stepped channel 211, so that the stepped channel 211 guides the syringe 130 to ensure that the syringe 130 can be aligned with the sample application region 121.

Illustratively, during the sampling process, one of the syringes 130 is selected to collect the test sample, and the syringe 130 is inserted into the step channel 211, and then the test sample is injected into the sample application region 121 by using the syringe 130. Subsequently, another syringe 130 is taken out to suck the diluent, and the diluent is injected into the sample addition part 121 while waiting for the display of the result.

Referring to fig. 1-3, in some embodiments, a cover 1111 is disposed in the storage chamber 111, and the cover 1111 has an integrally formed arc protrusion 1112. For example, the cover 1111 is engaged with the top end of the storage cavity 111, and the cover 1111 can be quickly detached by the engagement of the arc-shaped protrusion 1112. Simultaneously, can set up the sealing washer between apron 1111 and the top of storing chamber 111 to realize storing chamber 111's sealed, avoid the diluent to reveal.

Referring to fig. 1 to 3, in some embodiments, a viewing hole 115 communicating with the second accommodating chamber 113 is disposed at a side opposite to the first accommodating chamber 112, and a magnifying lens 1151 is embedded in the viewing hole 115; wherein the reagent card 120 further comprises a display area 122. For example, the position of the viewing aperture 115 is configured to correspond to the display area 122. After the display area 122 displays the result, the tester can view the displayed result more conveniently through the action of the magnifying lens 1151, thereby providing convenience for the tester.

Referring to fig. 1 to 3, in some embodiments, the body 110 is provided with a first sliding slot 116 that opens upward, and the first sliding slot 116 is provided with a freely slidable blocking cover 140. On one hand, the blocking cover 140 limits the reagent card 120 and the two syringes 130 in the second containing cavity 113 and the third containing cavity 114, respectively, so as to prevent the reagent card 120 or the two syringes 130 from falling; on the other hand, the sliding fit of the blocking cap 140 with the first chute 116 facilitates the tester to open the blocking cap 140 and take out the reagent card 120 or the two syringes 130.

Referring to fig. 1 and 4-6, in some embodiments, the stepped channel 211 includes an adapter hole 2111 and a drainage hole 2112 which are arranged in sequence from top to bottom, and the adapter hole 2111 communicates with the drainage hole 2112; for example, the aperture of the fitting hole 2111 is configured to be larger than the aperture of an empty barrel of the syringe 130. It can be seen that the empty barrel of syringe 130 can be fitted with the fitting hole 2111 to provide support for the empty barrel of syringe 130. Meanwhile, the drainage hole 2112 can provide a guiding function for the injection end of the syringe 130, so that the detection sample and the diluent can be fully utilized. In addition, the test sample or diluent can be injected directly into the adapter well 2111 and directed through the sidewall of the drainage well 2112 to the sample addition zone 121.

Referring to fig. 2-3 and 6, in some embodiments, a compartment 212 is provided within the housing 210, and the housing 210 is covered by a sealing cap 220 such that an end of the sealing cap 220 extends into the compartment 212. The sealing cover 220 seals the stepped channel 211 to prevent dust from entering, so that the body 110 can be better stored. For example, the sealing cover 220 forms a clearance fit with the interlayer 212; alternatively, the sealing cap 220 is threaded with the interlayer 212. Thereby facilitating quick removal of the sealing cap 220 by a tester.

Referring to fig. 2-3 and 6, in some embodiments, the sealing cap 220 is provided with an integrally formed linear protrusion 221. So that the sealing cover 220 is easily detached by the linear protrusion 221.

Referring to fig. 2-3 and 7-9, in some embodiments, further comprising a compression resilient member 300, the compression resilient member 300 being disposed between the sidewall of the second receiving chamber 113 and the reagent card 120; the extrusion rebound assembly 300 comprises a bottom plate 310, a push plate 320 and an extrusion rebound part 330, wherein two opposite telescopic pieces 321 are arranged between the push plate 320 and the bottom plate 310, a fourth accommodating cavity 311 is arranged on the bottom plate 310, and the extrusion rebound part 330 is arranged in the fourth accommodating cavity 311; wherein the compression springs 330 are configured to limit the position of the push plate 320 when the push plate 320 is subjected to a force.

According to the present embodiment, by the cooperation between the push plate 320 and the pressing spring-back portion 330, on the one hand, assembly can be facilitated at the time of production; on the other hand, when the tester cannot effectively inject the test sample or the diluent into the sample application region 121, the reagent card 120 may be removed, thereby providing the tester with various options.

Illustratively, when the pushing plate 320 is stressed, the pushing plate 320 generates a force on the pressing resilient portion 330 during moving leftward, and the pressing resilient portion 330 cooperates with the limiting pushing plate 320 to limit the position of the pushing plate 320, so as to completely place the reagent card 120 in the second accommodating cavity 113; similarly, when the pushing plate 320 is forced again, the pushing plate 320 exerts a force on the pressing resilient portion 330 during the leftward movement of the pushing plate 320, and the pressing resilient portion 330 cooperates with the limiting position of the pushing plate 320 to expose the portion of the reagent card 120 outside the second accommodating cavity 113.

Referring to fig. 7 to 9, in some embodiments, the extrusion resilient part 330 includes a moving plate 331, a push rod 332 and a connecting plate 333, two opposite linear sliding plates 3111 are disposed in the fourth accommodating cavity 311, a linear sliding slot 3312 adapted to the linear sliding plates 3111 is disposed on a side of the moving plate 331 opposite to the two linear sliding plates 3111, a moving hole 3112 is formed on a side of the moving plate 331 opposite to the push plate 320, the push rod 332 penetrates through the moving hole 3112 to fix one end of the push rod 332 to the moving plate 331, the other end of the push rod 332 is fixed to the push plate 320, a polygonal sliding slot 3311 is formed on the moving plate 331, a rotating shaft 3331 and a sliding rod 3332 are respectively fixed to two ends of the connecting plate 333, the rotating shaft 3331 is rotatably connected to the bottom plate 310, and the sliding rod 3332 is freely slidably connected to the polygonal sliding slot 3311.

According to the present embodiment, the sliding rod 3332 slides in the polygonal sliding slot 3311, and the moving plate 331 also reciprocates along the linear sliding plate 3111 through the linear sliding slot 3312, and when the sliding rod 3332 stays at different positions, the moving plate 331 drives the push rod 332 to stop the push plate 320 at different positions, thereby positioning the push plate 320.

Illustratively, referring to FIGS. 7-9, when in the initial state, the post 3332 is disposed in a channel opposite the third sidewall 33113; when in the retracted state, the post 3332 is disposed in the groove opposite the first and

second sidewalls

33111, 33112.

Referring to fig. 7 to 9, in some embodiments, the pressing resilient part 330 further includes an elastic member 334, and the elastic member 334 is disposed between a side wall of the fourth receiving cavity 311 and the moving plate 331. The elastic member 334 is, for example, a spring. A first positioning post 3113 is fixed on a side wall of the fourth accommodating cavity 311 opposite to the moving plate 331, a second positioning post 3313 is fixed on a side of the moving plate 331 away from the push rod 332, one end of the elastic member 334 is sleeved on the first positioning post 3113 and abuts against the side wall of the fourth accommodating cavity 311 opposite to the moving plate 331, and the other end of the elastic member 334 is sleeved on the second positioning post 3313 and abuts against the moving plate 331. The elastic member 334 can realize the rebound of the sliding rod 3332 to the groove corresponding to the third sidewall 33113 by the restoration effect after the deformation.

Referring to fig. 7-9, in some embodiments, the polygonal chute 3311 includes a first sidewall 33111, a second sidewall 33112, and a third sidewall 33113; wherein the inclination angle of the first sidewall 33111 is configured to be larger than that of the second sidewall 33112, and the third sidewall 33113 is configured to form a non-parallel arrangement with the opposite sidewall. When the sliding rod 3332 moves, it can slide to the left when encountering the third side wall 33113; and meets the first sidewall 33111 and instantaneously falls into the groove where the first sidewall 33111 and the second sidewall 33112 oppose each other. When the sliding bar 3332 moves again, it encounters the second sidewall 33112 and slides to the right, and finally falls into the groove opposite to the third sidewall 33113.

Referring to fig. 10, another embodiment of the present invention provides a method for using a detection kit, including the following steps:

s1, a tester selects one injector 130 from the third containing cavity 114, sucks a detection sample by using the one injector 130, inserts the detection sample into the stepped channel 211 through the one injector 130, and injects the detection sample into the sample adding region 121;

s2, the tester takes out another syringe 130 from the third containing cavity 114, uses the other syringe 130 to suck the diluent from the storage cavity 111, inserts the diluent into the stepped channel 211 through the other syringe 130, and injects the diluent into the sample injection region 121;

s3, when the test sample or the diluent cannot be injected effectively, the moving plate 331 moves away from the push rod 332 by pressing the reagent card 120, the sliding rod 3332 slides right instantly after encountering the second sidewall 33112 and finally falls into the groove opposite to the third sidewall 33113, and then the reagent card 120 is taken out and injected into the test sample or the diluent.

Above, the openings of the storage cavity 111, the first accommodating cavity 112 and the observation hole 115 face upward, and the openings of the second accommodating cavity 113 and the third accommodating cavity 114 face rightward. The housing of the reagent card 120 is made of plastic.

It should be noted that the model specification of the reagent card 120 needs to be determined by type selection according to the actual specification of the device, and the specific type selection adopts the prior art in the field, so detailed description is omitted.

The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes may be made to the present invention by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A test kit, comprising:

2. The detection kit according to claim 1, wherein a cover plate is disposed in the storage chamber, and the cover plate has an integrally formed arc protrusion.

3. The detection kit as claimed in claim 1, wherein a viewing hole communicating with the second accommodating chamber is disposed at a side opposite to the first accommodating chamber, and a magnifying lens is embedded in the viewing hole;

4. The detection kit according to claim 1, wherein the body has a first chute with an upward opening, and the first chute has a freely slidable blocking cover.

5. The detection kit according to claim 1, wherein the stepped channel comprises an adapter hole and a drainage hole which are arranged from top to bottom in sequence, and the adapter hole is communicated with the drainage hole;

6. The test kit as claimed in claim 1, wherein the housing has a sandwich layer, the housing is covered with a sealing cover, and an end of the sealing cover extends into the sandwich layer.

7. The detection kit according to claim 1, further comprising a squeezing springback assembly, wherein the squeezing springback assembly is arranged between the side wall of the second containing cavity and the reagent card; the extrusion resilience assembly comprises a bottom plate, a push plate and an extrusion resilience part, two opposite telescopic pieces are arranged between the push plate and the bottom plate, a fourth accommodating cavity is formed in the bottom plate, and the extrusion resilience part is arranged in the fourth accommodating cavity;

8. The detection kit according to claim 7, wherein the extrusion resilient portion comprises a movable plate, a push rod and a connecting plate, two opposite linear sliding plates are disposed in the fourth accommodating cavity, a linear sliding groove adapted to the linear sliding plates is disposed on a side of the movable plate opposite to the two linear sliding plates, a moving hole is formed in a side of the movable plate opposite to the push plate, the push rod penetrates through the moving hole, so that one end of the push rod is fixed to the movable plate, the other end of the push rod is fixed to the push plate, a polygonal sliding groove is formed in the movable plate, a rotating shaft and a sliding rod are respectively fixed to two ends of the connecting plate, the rotating shaft is rotatably connected to the bottom plate, and the sliding rod is freely slidably connected to the polygonal sliding groove.

9. The detection kit according to claim 8, wherein the resilient member further comprises an elastic member disposed between the side wall of the fourth accommodating cavity and the movable plate.

10. The test kit of claim 8, wherein the polygonal chute comprises a first side wall, a second side wall, and a third side wall; wherein an inclination angle of the first sidewall is configured to be greater than an inclination angle of the second sidewall, and the third sidewall is configured to form a non-parallel arrangement with an opposite sidewall.