CN115892648A - Partial shipment device of material ball - Google Patents

Abstract

The application relates to the field of biomedical science and discloses a partial shipment device of material ball, and this application partial shipment device of material ball includes: the feeding pipeline is vertically arranged and is provided with a feeding pipeline inlet at the top and a feeding pipeline outlet at the bottom; the split charging part comprises a housing and a roller which is rotatably arranged in the housing, the peripheral surface of the roller is provided with a plurality of split charging accommodating parts which are circumferentially separated, the housing is provided with a top opening and a bottom opening, and the top opening is communicated with the outlet of the feeding pipeline; the drying part, the feeding pipeline and the split charging part are arranged in a drying cavity of the drying part. The material ball subpackaging device has the advantages that the material balls can be subpackaged automatically, the defect of the traditional manual one-by-one subpackaging is overcome, and the material ball subpackaging device is easy to operate, high in efficiency and capable of being automated; meanwhile, a drying cavity is arranged in the subpackaging device, so that the problem that the material balls are contacted with air for a long time to absorb moisture, shrink and stick to the wall in the subpackaging process can be avoided.

Description

Partial shipment device of material ball

Technical Field

The application relates to the field of biomedical, especially, relate to partial shipment device of material ball.

Background

The biological agent has high requirement on storage environment in the using process, the high-temperature environment easily causes unstable enzyme activity and impaired activity, the prior art usually adopts cold chain transportation and low-temperature storage modes for keeping alive, but the storage mode has the defects of instability, high cost, short quality guarantee period and the like. In order to overcome the defects, a novel technology in the field of freeze-drying is developed, namely a freeze-drying ball technology, the technology has the advantages of accurate quantification, single unit, convenience in use of products and the like, has no requirement on packaging materials, can be subpackaged into packaging materials such as eight-connecting tubes, centrifuge tubes, microfluidic chips, various biological chip cards, flow tubes, 96-hole plates and the like, and can be stored at normal temperature to realize rapid diagnosis. Because the limitation of the packing material is not provided, the production capacity can be exerted to the limit of the freeze dryer. However, the freeze-dried ball has the defects that the development difficulty is very strict, the freeze-dried ball is very fragile and easy to fall off, and the freeze-dried ball is small in size and light in weight and easy to rub to generate static electricity; if the freeze-dried balls are contacted with air for a long time and easily absorb moisture and shrink, the requirements on the packaging environment and packaging equipment are very strict, and the freeze-dried balls are generally packaged manually in the market at present, which is one of the reasons that the freeze-dried balls cannot be produced on a large scale at a later time.

Disclosure of Invention

The invention aims to provide a material ball subpackaging device, which can realize automatic subpackaging of freeze-dried beads, overcomes the defect of the traditional manual subpackaging one by one, and has the characteristics of easy operation, high efficiency and automation; meanwhile, the problem that the freeze-dried beads are contacted with air for a long time to absorb moisture, shrink and stick to the wall in the split charging process is avoided.

For solving the technical problem, a first aspect of the present application provides a partial shipment device of material ball, includes: a feed conduit vertically disposed, the feed conduit having a top feed conduit inlet and a bottom feed conduit outlet; the split charging part comprises a housing and a roller which is rotatably arranged in the housing, the peripheral surface of the roller is provided with a plurality of split charging accommodating parts which are circumferentially separated, the housing is provided with a top opening and a bottom opening, and the top opening is communicated with the outlet of the feeding pipeline; the drying part, the feed conduit with the partial shipment portion is located in the drying chamber of drying part.

In an embodiment of the first aspect, the side wall of the feed conduit is provided with a plurality of gas injection openings, which open into the feed conduit.

In an embodiment of the first aspect, the plurality of gas injection ports comprises at least one first gas injection port arranged laterally and at least one second gas injection port arranged diagonally downwards towards the interior of the feed conduit.

In an embodiment of the first aspect, the at least one first gas injection port is two first gas injection ports, the two first gas injection ports being located at the bottom and the top of the feed conduit, respectively; and the at least one second gas injection port is two second gas injection ports, and the two first gas injection ports are respectively positioned at the bottom and the top of the feeding pipeline.

In an embodiment of the first aspect, the separate loading container is a plurality of cavities on the outer circumferential surface of the drum, and each cavity is located on the same radial plane as the top opening and the bottom opening.

In an embodiment of the first aspect, the diameter of the feed conduit is 10% to 40% larger than the predetermined acceptable diameter of the material pellets.

In an embodiment of the first aspect, the bottom of the dispensing container portion is provided with a vent hole, which is arranged to communicate with the air pump.

In an embodiment of the first aspect, the device further comprises a discharge pipeline, the discharge pipeline is vertically arranged, the discharge pipeline has a discharge pipeline inlet at the top and a discharge pipeline outlet at the bottom, and the bottom opening of the housing is communicated with the discharge pipeline inlet.

In an embodiment of the first aspect, further comprising a cover removably connected to the outfeed conduit outlet of the outfeed conduit.

In an embodiment of the first aspect, inner wall surfaces of the inlet duct, the outlet duct and the dispensing trough are coated with an antistatic layer.

The automatic packaging machine has the advantages that the freeze-dried beads can be automatically packaged one by rotating the rotary disc, the defect of the traditional manual packaging one by one is overcome, and the automatic packaging machine has the characteristics of easiness in operation, high efficiency and automation; simultaneously with the partial shipment device setting in dry chamber, can avoid freeze-dried pearl at the partial shipment in-process, long-time and air contact and the problem that the wall is glued to the atrophy of absorbing moisture.

Drawings

FIG. 1 is a schematic view of a material ball sub-packaging apparatus according to an embodiment of the present disclosure;

fig. 2 is a schematic structural diagram of a dispensing device for material balls including freeze-dried beads according to an embodiment of the present disclosure.

Detailed Description

The following description of the embodiments of the present application is provided by way of specific examples, and other advantages and effects of the present application will be readily apparent to those skilled in the art from the disclosure herein. The present application is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present application. It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict.

Embodiments of the present application will be described in detail below with reference to the accompanying drawings so that those skilled in the art to which the present application pertains can easily carry out the present application. The present application may be embodied in many different forms and is not limited to the embodiments described herein.

In order to clearly explain the present application, components that are not related to the description are omitted, and the same reference numerals are given to the same or similar components throughout the specification.

Throughout the specification, when a device is referred to as being "connected" to another device, this includes not only the case of being "directly connected" but also the case of being "indirectly connected" with another element interposed therebetween. In addition, when a device "includes" a certain component, unless otherwise stated, the device does not exclude other components, but may include other components.

When a device is said to be "on" another device, this may be directly on the other device, but may also be accompanied by other devices in between. When a device is said to be "directly on" another device, there are no other devices in between.

Although the terms first, second, etc. may be used herein to describe various elements in some instances, these elements should not be limited by these terms. These terms are only used to distinguish one element from another. For example, the first interface and the second interface, etc. are described. Also, as used herein, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context indicates otherwise. It will be further understood that the terms "comprises," "comprising," "includes" and/or "including," when used in this specification, specify the presence of stated features, steps, operations, elements, components, items, species, and/or groups, but do not preclude the presence, or addition of one or more other features, steps, operations, elements, components, items, species, and/or groups thereof. The terms "or" and/or "as used herein are to be construed as inclusive or meaning any one or any combination. Thus, "a, B or C" or "a, B and/or C" means "any of the following: a; b; c; a and B; a and C; b and C; A. b and C ". An exception to this definition will occur only when a combination of elements, functions, steps or operations are inherently mutually exclusive in some way.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used herein, the singular forms "a", "an" and "the" include plural forms as long as the words do not expressly indicate a contrary meaning. The term "comprises/comprising" when used in this specification is taken to specify the presence of stated features, regions, integers, steps, operations, elements, and/or components, but does not exclude the presence or addition of other features, regions, integers, steps, operations, elements, and/or components.

Terms representing relative spatial terms such as "lower", "upper", and the like may be used to more readily describe one element's relationship to another element as illustrated in the figures. Such terms are intended to include not only the meanings indicated in the drawings, but also other meanings or operations of the device in use. For example, if the device in the figures is turned over, elements described as "below" other elements would then be oriented "above" the other elements. Thus, the exemplary terms "under" and "beneath" all include above and below. The device may be rotated 90 or other angles and the terminology representing relative space is to be interpreted accordingly.

Although not defined differently, including technical and scientific terms used herein, all terms have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. Terms defined in commonly used dictionaries are to be additionally interpreted as having meanings consistent with those of related art documents and the contents of the present prompts, and must not be excessively interpreted as having ideal or very formulaic meanings unless defined.

Partial shipment device of material ball includes: the device comprises a feeding pipeline, a split charging part and a drying part, wherein the feeding pipeline is vertically arranged and is provided with a feeding pipeline inlet at the top and a feeding pipeline outlet at the bottom; the split charging part comprises a housing and a roller which is rotatably arranged in the housing, the peripheral surface of the roller is provided with a plurality of split charging accommodating parts which are circumferentially separated, the housing is provided with a top opening and a bottom opening, and the top opening is communicated with the outlet of the feeding pipeline; the feeding pipeline and the sub-packaging part are arranged in the drying cavity of the drying part. The material ball in this embodiment is a freeze-dried bead, and other materials, such as freeze-dried ball and freeze-dried micro core, are also practical.

The first embodiment of the present application is described below with reference to the accompanying drawings, as shown in fig. 1 and fig. 2, the material ball sub-packaging device of the present application comprises a feeding pipe 1, a sub-packaging part 2 and a drying part 3, the feeding pipe 1 is vertically arranged, the feeding pipe 1 has a feeding pipe inlet 11 at the top and a feeding pipe outlet 12 at the bottom, the diameter of the feeding pipe 1 is 10% -40% larger than the preset acceptable diameter of the freeze-dried beads, freeze-dried beads or a plurality of freeze-dried beads adhered together, which exceed the size range, cannot enter the feeding pipe 1, and freeze-dried beads of acceptable size entering the feeding pipe 1 can be sequentially and adjacently arranged in the feeding pipe 1 along the vertical direction. In some embodiments, the side wall of the feed conduit 1 is provided with a plurality of gas nozzles, each opening into the feed conduit 1. The plurality of air injection ports include a pair of first air injection ports 41 arranged laterally and a pair of second air injection ports 42 arranged obliquely downward toward the inside of the feed duct 1. Specifically, a pair of first air ports 41 are located at the top and bottom of the feed pipe 1, respectively, and a pair of second air ports 42 are located at the top and bottom of the feed pipe 1, respectively, thereby forming one first air port 41 and one second air port 42 at the top of the feed pipe 1, and one first air port 41 and one second air port 42 at the bottom of the feed pipe. The first air nozzles 41 transversely arranged at the top and the bottom can spray transverse air flow into the feeding pipeline 1 to prevent freeze-dried beads from being adhered to the wall due to moisture absorption in the packaging process. The oblique downward air current of second air jet 42 blowout that top and bottom set up downwards to one side promotes freeze-drying pearl and moves down, avoids freeze-drying pearl because of small, moisture low and mutual friction produces static, floats in the charge-in pipeline. In addition, the gas flow ejected from the gas nozzle is inert gas such as nitrogen, so that the reaction with the freeze-dried balls is avoided.

It is understood that one first gas jet 41 and one second gas jet 42 can be arranged opposite one another on the same radial plane of the feed conduit 1 or can be arranged offset from one another on different radial planes of the feed conduit 1. In some embodiments, only one first air nozzle 41 and one second air nozzle 42 may be disposed on the side wall of the feed pipe 1, or more first air nozzles 41 and second air nozzles 42 may be disposed, and the number of the air nozzles may be selected according to the length of the feed pipe 1, and the air nozzles may be disposed at different positions of the side wall of the feed pipe 1, such as the bottom, the middle, the top, and the like, respectively, so as to obtain better dispensing efficiency.

The dispensing portion 2 of the dispensing apparatus of the present application includes a roller 21 and a housing 22, wherein the roller 21 is rotatably disposed in the housing 22. In the preferred embodiment shown in fig. 1, the housing 22 is cylindrical and the drum 21 is cylindrical, both being concentrically arranged. The outer circumferential surface of the drum 21 is provided with a sub-packaging containing portion 23 for containing a material such as freeze-dried beads. Housing 22 has a top opening (not shown) and a bottom opening (not shown) that communicate with feed conduit outlet 12 to receive the lyophilized beads from feed conduit outlet 12. Specifically, the dispensing receptacles 23 are circumferentially spaced on the outer circumferential surface of the drum 21 and are a plurality of cavities on the outer circumferential surface of the drum 21, each cavity being located on the same radial plane as the top and bottom openings so that as the drum 21 rotates within the housing 22, each cavity is sequentially aligned with the top opening to receive the lyophilized beads from the feed conduit outlet 12 and each cavity is also sequentially aligned with the bottom opening to transfer the lyophilized beads to the dryer section 3. Specifically, when the drum 21 is rotated until the dispensing container 23 faces the inlet conduit outlet 12, the lyophilized beads enter the dispensing container 23 from the inlet conduit 1. Preferably, under the assistance of the second air jet 42 that sets up under the bottom slant, through slant decurrent second air jet 42 blowout air current, push into partial shipment portion 23 with freeze-drying pearl completely, avoid freeze-drying pearl card between partial shipment portion 23 and charge-in pipeline export 12, send garrulous with the charge-in pipeline collision during the rotation. The drum 21 may include 4 sub-compartments 23 as shown in fig. 1, or may include 8 or other numbers, and two sub-compartments are provided at two ends of the diameter of the radial surface. Further, a vent hole 24 is provided in the bottom of the separate-charging accommodating portion 23, and the vent hole 24 is provided so as to be communicable with an air pump (not shown). When the unloaded subpackage accommodating part 23 rotates to be vertically upward, the bottom air hole 24 in the subpackage accommodating part 23 can suck air flow through the air pump, freeze-dried beads are better assisted to completely fall into the subpackage accommodating part 23, meanwhile, the subpackage accommodating part 23 with the freeze-dried balls loaded at the other end of the diameter on the radial surface rotates to be vertically downward, the bottom air hole 24 of the subpackage accommodating part 23 pushes the freeze-dried balls out of the subpackage accommodating part 23 through air flow sprayed by the air pump, and the freeze-dried balls enter a product container (not shown in the figure) corresponding to the lower part through the bottom opening of the housing 22. The bottom vent holes 24 of the sub-packaging containing parts 23 can be communicated with the same air pump, the vertically upward bottom vent hole air flow at one end is pumped to the vertically downward bottom vent hole at the other end, and the switch air valves 25 are arranged between the vent holes 24 and the pressurized air source, when the sub-packaging containing parts 23 are just opposite to the bottom opening of the housing 22 below, the corresponding switch air valves 25 are controlled to be opened to spray the air flow, the freeze-dried beads are pushed out of the sub-packaging containing parts 23, and the rest switch air valves 25 are kept in a closed state. In the present invention, the dispensing container 23 may be designed to contain a predetermined amount of material, for example, in the case of freeze-dried beads, a specific amount of freeze-dried beads may be contained, so as to achieve quantitative transfer and dispensing of the freeze-dried beads.

In some embodiments, this application partial shipment device still includes ejection of compact pipeline 5, and ejection of compact pipeline 5 vertical setting, ejection of compact pipeline 5 have the ejection of compact pipeline import 51 at top and the ejection of compact pipeline export 52 of bottom, and the bottom opening and the ejection of compact pipeline import 51 intercommunication of housing 22, freeze-dried pearl leave and get into to ejection of compact pipeline 5 in through ejection of compact pipeline import 51 behind the partial shipment portion 23, during rethread ejection of compact pipeline 5 gets into corresponding partial shipment container. It should be understood that the side wall of the discharge duct 5 may be provided with a first air jet 41 and a second air jet 42 similar to those of the feed duct 1, which will not be described in detail herein. The inlet 11 of the inlet pipeline 1 and the outlet 52 of the outlet pipeline 5 may be detachably connected with a cover (not shown in the figure), after the split charging is finished, the cover can be covered, and the contact between the inner cavity of the split charging device and the external environment during the non-operation is reduced. In addition, this application partial shipment device can adopt plastics materials such as PP, PE or PET to at the inner wall surface coating antistatic backing that freeze-drying pearl probably contacted, for example the inner wall surface coating that holds the portion at charge-in pipeline, ejection of compact pipeline and partial shipment has antistatic backing, also can adopt metal material such as stainless steel, through making it possess the function of destaticing with its earth connection, reduce electrostatic action as far as and lead to freeze-drying pearl to produce and glue wall jam scheduling problem.

This application partial shipment device still includes drying portion 3, and drying portion 3 has dry chamber 31, and charge-in pipeline 1 and ejection of compact pipeline 5 can all be located in dry chamber 31 to and partial shipment portion 2 also can locate in dry chamber 31 (not shown in the figure), guarantee that the freeze-dried ball is in a dry environment at the partial shipment in-process always. In some embodiments, at least part of the inlet duct 1 and the outlet duct 5 is provided with a plurality of meshes communicating with the drying chamber 31, and at least part of the sub-section 2 may also be provided with a plurality of meshes communicating with the drying chamber 31, thereby achieving more excellent drying efficiency.

The automatic packaging machine realizes automatic and one-by-one packaging of freeze-dried beads by rotating the turntable, overcomes the defect of the traditional manual particle-by-particle packaging, and has the characteristics of easy operation, high efficiency and automation; simultaneously, the split charging device is arranged in the drying cavity, so that the problem that freeze-dried beads are contacted with air for a long time and absorb moisture, shrink and stick to the wall in the split charging process can be avoided.

The above embodiments are merely illustrative of the principles and utilities of the present application and are not intended to limit the application. Any person skilled in the art can modify or change the above-described embodiments without departing from the spirit and scope of the present application. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical concepts disclosed in the present application shall be covered by the claims of the present application.

Claims (10)

1. The utility model provides a partial shipment device of material ball which characterized in that includes:

a feed conduit vertically disposed, the feed conduit having a feed conduit inlet at a top and a feed conduit outlet at a bottom;

the split charging part comprises a housing and a roller which is rotatably arranged in the housing, the peripheral surface of the roller is provided with a plurality of split charging accommodating parts which are circumferentially separated, the housing is provided with a top opening and a bottom opening, and the top opening is communicated with the outlet of the feeding pipeline;

the drying part, the feed conduit with the partial shipment portion is located in the drying chamber of drying part.

2. The racking device of claim 1 wherein said side wall of said feed conduit is provided with a plurality of air jets, said plurality of air jets opening into said feed conduit.

3. A racking device according to claim 2 wherein said plurality of air jets comprises at least one first transversely disposed air jet and at least one second obliquely downwardly disposed air jet inwardly of said feed conduit.

4. A dispensing apparatus according to claim 3 wherein the at least one first air jet is two first air jets located at the bottom and top of the feed conduit respectively; and the at least one second gas orifice is two second gas orifices, and the two first gas orifices are respectively positioned at the bottom and the top of the feed pipeline.

5. A racking device as claimed in claim 1 wherein said racking receptacle is a plurality of cavities in said drum peripheral surface, each of said cavities being located in the same radial plane as said top opening and said bottom opening.

6. The racking device of claim 1 wherein said feed conduit has a diameter between 10% and 40% greater than a predetermined acceptable diameter of said material balls.

7. The racking device of claim 1 wherein said bottom of said racking receptacle is provided with a vent, said vent being configured to communicate with an air pump.

8. The racking device of claim 1 further comprising a discharge conduit, said discharge conduit being vertically disposed, said discharge conduit having a top discharge conduit inlet and a bottom discharge conduit outlet, wherein said bottom opening of said housing is in communication with said discharge conduit inlet.

9. The racking device according to claim 8 further comprising a closure removably connected to said discharge conduit outlet of said discharge conduit.

10. The dispensing apparatus as claimed in claim 8 wherein the inner wall surfaces of the inlet conduit, the outlet conduit and the dispensing container are coated with an antistatic layer.

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