CN115877011A

CN115877011A - Sample analyzer and detection method thereof

Info

Publication number: CN115877011A
Application number: CN202111136335.2A
Authority: CN
Inventors: 梁绮云
Original assignee: Shenzhen Dymind Biotechnology Co Ltd
Current assignee: Shenzhen Dymind Biotechnology Co Ltd
Priority date: 2021-09-27
Filing date: 2021-09-27
Publication date: 2023-03-31

Abstract

The application discloses sample analyzer and detection method thereof, this sample analyzer includes: a sample module for collecting and distributing samples; a reagent supply module for supplying a reagent; the specific protein detection module is used for detecting a plurality of specific protein detection items of a sample; the control module is respectively connected with the sample module, the reagent supply module, the specific protein detection module and the storage module and is used for storing the plurality of calibration curves to the storage module; when the specific protein detection module performs a first specific protein detection item on the sample, the control module obtains a first calibration curve corresponding to the first specific protein detection item from the plurality of calibration curves, and obtains a first detection result based on the first calibration curve. By the mode, re-calibration is not needed, the calibration flow time is shortened, the consumption of the calibration reagent is reduced, and the use experience of a user is improved.

Description

Sample analyzer and detection method thereof

Technical Field

The application relates to the technical field of blood sample analysis, in particular to a sample analyzer and a detection method thereof.

Background

With the gradual popularization of specific proteins, the sample analyzers in the prior art are used for detecting specific proteins in blood samples to obtain detection results. The sample analyzer in the prior art needs to be calibrated again when the mode is switched every time, so that the consumption of calibration reagents is large, and the use experience of a user is poor.

Disclosure of Invention

In order to solve the above problems, the present application provides a sample analyzer and a detection method thereof, which can reduce the consumption of calibration reagents by obtaining a first calibration curve corresponding to a first specific protein detection item from a plurality of calibration curves without re-calibration.

The technical scheme adopted by the application is as follows: there is provided a sample analyzer comprising: a sample module for collecting and distributing samples; a reagent supply module for supplying a reagent; at least one specific protein detection module for performing a plurality of specific protein detection items on the sample; the control module is respectively connected with the sample module, the reagent supply module, the specific protein detection module and the storage module and is used for storing a plurality of calibration curves into the storage module; when the specific protein detection module performs a first specific protein detection item on the sample, the control module obtains a first calibration curve corresponding to the first specific protein detection item from the calibration curves, and obtains a first detection result based on the first calibration curve.

The application adopts another technical scheme that: providing a sample analyzer, the sample analyzer comprising: a sample module for collecting and distributing samples; a reagent supply module for supplying a reagent; a blood routine detection module for performing blood routine detection on the sample; at least one specific protein detection module for performing a plurality of specific protein detection items on the sample; the control module is respectively connected with the sample module, the reagent supply module, the specific protein detection module and the storage module and is used for storing a plurality of calibration curves into the storage module; when the specific protein detection module performs a first specific protein detection item on the sample, the control module obtains a first calibration curve corresponding to the first specific protein detection item from the calibration curves, and obtains a first detection result based on the first calibration curve.

Another technical scheme adopted by the application is as follows: there is provided a detection method of a sample analyzer, the detection method comprising: storing a plurality of calibration curves to the storage module; and when the specific protein detection module performs a first specific protein detection item on the sample, acquiring a first calibration curve corresponding to the first specific protein detection item from the calibration curves, and obtaining a first detection result based on the first calibration curve.

The sample analyzer comprises a sample module, a reagent supply module, at least one specific protein detection module, a control module and a storage module, wherein the specific protein detection module is used for carrying out multiple specific protein detection items on a sample; when the specific protein detection module performs a first specific protein detection item on the sample, the control module obtains a first calibration curve corresponding to the first specific protein detection item from the plurality of calibration curves, and obtains a first detection result based on the first calibration curve. A plurality of calibration curves are stored through the storage module, and the control module obtains the corresponding first calibration curve from the plurality of calibration curves, so that the sample analyzer does not need to be calibrated again during mode switching, the calibration flow time is shortened, the consumption of calibration reagents is reduced, and the use experience of a user is improved.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts. Wherein:

FIG. 1 is a block diagram of a first embodiment of a sample analyzer of the present application;

FIG. 2 is a schematic block diagram of one embodiment of the specific protein detection module of FIG. 1;

FIG. 3 is a schematic block diagram of another embodiment of the specific protein detection module of FIG. 1;

FIG. 4 is a block diagram of a second embodiment of the sample analyzer of the present application;

FIG. 5 is a schematic structural view of a third embodiment of the sample analyzer of the present application;

FIG. 6 is a schematic structural view of a fourth embodiment of the sample analyzer of the present application;

FIG. 7 is a schematic flow chart of a first embodiment of a detection method of the sample analyzer of the present application;

FIG. 8 is a schematic flow chart of a second embodiment of a detection method of the sample analyzer of the present application;

FIG. 9 is a schematic flow chart of a third embodiment of a detection method of the sample analyzer of the present application;

fig. 10 is a schematic flow chart of a fourth embodiment of the detection method of the sample analyzer of the present application.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. It is to be understood that the specific embodiments described herein are merely illustrative of the application and are not limiting of the application. It should be further noted that, for the convenience of description, only some of the structures related to the present application are shown in the drawings, not all of the structures. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The terms "first", "second", etc. in this application are used to distinguish between different objects and not to describe a particular order. Furthermore, the terms "include" and "have," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein may be combined with other embodiments.

The application of the sample analyzer is applied to the field of medical treatment or biochemical analysis, and is used for detecting various tiny particles in a sample so as to count the particles, and the more common sample analyzer can be a blood cell analyzer.

The sample analyzer of the present application may be used to detect a specific protein in a sample, where the specific protein includes one of SAA (serum amyloid a protein), CRP (C-reactive protein ), TRF (tramsferrin, transferrin), hs-CRP (hypersensitive C-reactive protein), PCT (procalcitonin ), and D-Dimer (D-Dimer).

Referring to fig. 1, fig. 1 is a schematic structural diagram of a first embodiment of a sample analyzer according to the present application. The sample analyzer 10 of the present embodiment includes a sample module 11, a reagent supply module 12, at least one specific protein detection module 13, a control module 14, and a storage module 15. Wherein, the control module 14 is respectively connected with the sample module 11, the reagent supply module 12, the at least one specific protein detection module 13 and the storage module 15.

The sample module 11 is used to collect and dispense a sample, which may be a blood sample. Wherein the sample module 11 can be used to collect a sample from a test tube and distribute the sample to the corresponding specific protein detection module 13.

The reagent supply module 12 is used for supplying a reagent; for example, the reagent supply module 12 is used to draw reagents from reagent containers and add the reagents to the corresponding specific protein detection module 13.

The specific protein detection module 13 is configured to perform a plurality of specific protein detection items on the sample, where the specific protein detection items may include a SAA detection item, a CRP detection item, a TRF detection item, an Hs-CRP detection item, a PCT detection item, or a D-Dimer detection item. Each specific protein test item has corresponding reagents, such as: the SAA detection item corresponds to a first reagent, and the CRP detection item corresponds to a second reagent; therefore, the control module 14 can control the reagent supply module 12 to supply the corresponding reagent to the specific protein detection module 13 according to the specific protein detection item of the specific protein detection module 13.

The specific protein detection module 13 of the embodiment is used for performing a plurality of specific protein detection items on a sample, and can realize channel multiplexing and improve user experience.

In the case where the sample analyzer 10 includes a plurality of specific protein detection modules 13, at least one specific protein detection module 13 of the plurality of specific protein detection modules 13 is used to perform a plurality of specific protein detection items on the sample. For example, one specific protein detection module 13 of the plurality of specific protein detection modules 13 is used for detecting a plurality of specific protein detection items on the sample, and the other specific protein detection modules 13 are respectively used for detecting one specific protein detection item on the sample; alternatively, each specific protein detection module 13 of the plurality of specific protein detection modules 13 is used for detecting a plurality of specific protein detection items on the sample.

The control module 14 is configured to store the plurality of calibration curves in the storage module 15, i.e. the storage module 15 is configured to store the plurality of calibration curves. The calibration curves are respectively corresponding to a plurality of specific protein detection items one by one, that is, each specific protein detection item in each specific protein detection module 13 corresponds to one calibration curve.

Alternatively, the control module 14 scales all the specific protein detection items of each specific protein detection module 13 to obtain a plurality of scaling curves, and stores the plurality of scaling curves in the storage module 15.

In other embodiments, when a plurality of specific protein detection modules 13 are used to detect the same specific protein detection item on the sample, the detection of the specific protein detection item may correspond to a calibration curve, that is, the plurality of specific protein detection modules 13 all use the same calibration curve when detecting the specific protein detection item on the sample. Therefore, the control module 14 scales the same specific protein detection item of the specific protein detection module 13 to obtain a scaling curve, and stores the scaling curve in the storage module 15.

When the specific protein detection module 13 is configured to detect a first specific protein detection item on a sample, the control module 14 is configured to obtain a first calibration curve corresponding to the first specific protein detection item from the plurality of calibration curves of the storage module 15, and obtain a first detection result based on the first calibration curve. That is, the control module 14 controls the specific protein detection module 13 to perform the detection of the first specific protein detection item on the sample, and the control module 14 obtains the first calibration curve from the plurality of calibration curves and obtains a first detection result based on the first calibration curve, where the first detection result includes a parameter of the first specific protein detection item.

For example, the specific protein detection module 13 may perform SAA test items and CRP test items on the sample; when the control module 14 controls the specific protein detection module 13 to detect the SAA detection item on the sample, the control module 14 obtains a calibration curve corresponding to the SAA detection item from the plurality of calibration curves; when the control module 14 controls the specific protein detection module 13 to detect the CRP detection item on the sample, the control module 14 obtains a calibration curve corresponding to the CRP detection item from the plurality of calibration curves.

The control module 14 of this embodiment stores the plurality of calibration curves in the storage module 15, and when the specific protein detection module 13 is configured to perform detection on a first specific protein detection item on a sample, the control module 14 is configured to obtain a first calibration curve corresponding to the first specific protein detection item from the plurality of calibration curves in the storage module 15, and obtain a first detection result based on the first calibration curve; therefore, when the mode of the sample analyzer 10 is switched, the control module 14 obtains the corresponding calibration curves from the plurality of calibration curves stored in the storage module 15, re-calibration is not needed, the calibration flow time is shortened, the consumption of the calibration reagent is reduced, and the use experience of a user is improved.

In one embodiment, each specific protein detection module 13 includes a reaction cell 131, as shown in FIG. 2. The sample module 11 distributes the sample to the reaction cell 131, and the reagent supply module 12 supplies the corresponding reagent to the reaction cell 131 of the specific protein detection module 13, so that the sample and the reagent in the reaction cell 131 react. The control module 14 detects the first specific protein detection item on the reacted sample through the reaction tank 131, and then the control module 14 obtains a first calibration curve from the plurality of calibration curves and obtains a first detection result based on the first calibration curve. Thus, the reaction cell 131 of the specific protein detection module 13 is used to perform reaction and detection. In other embodiments, the reaction cell 131 may be referred to as a detection cell, a reaction cup, or the like.

In one embodiment, each specific protein detection module 13 includes a reaction cell 131 and a detection cell 132, as shown in fig. 3. The sample module 11 distributes the sample to the reaction cell 131, and the reagent supply module 12 supplies the corresponding reagent to the reaction cell 131 of the specific protein detection module 13, so that the sample and the reagent in the reaction cell 131 react. The control module 14 performs detection on the reacted sample through the detection cell 132 for a first specific protein detection item, and then the control module 14 obtains a first calibration curve from the plurality of calibration curves and obtains a first detection result based on the first calibration curve. Therefore, the reaction cell 131 of the specific protein detection module 13 is used to perform a reaction, and the detection cell 132 is used to perform a detection.

In an embodiment, as shown in fig. 4, the sample analyzer 10 further includes a display module 16, the display module 16 is connected to the control module 14, and when the control module 14 obtains the first detection result based on the first calibration curve, the display module 16 is configured to display the first detection result, so as to improve the user experience.

In one embodiment, the plurality of specific protein detection items includes a first specific protein detection item and a second specific protein detection item, and when the control module 14 controls the specific protein detection module 13 to switch from the second specific protein detection item to the first specific protein detection item, that is, the sample analyzer 10 performs the mode switch, the control module 14 determines whether the storage module 15 includes a first calibration curve corresponding to the first specific protein detection item; if not, the control module 14 controls the specific protein detection module 13 to calibrate the first specific protein detection item to obtain a first calibration curve, and stores the first calibration curve in the storage module 15.

In one embodiment, the control module 14 tests a plurality of standard samples with predetermined concentration values through the specific protein detection module 13 to obtain measured values. The control module 14 obtains a first calibration curve based on a regression curve between the preset concentration value and the measured value. The number of the standard samples of the preset concentration value may be 2, 4, 6, or 8, etc. Therefore, the control module 14 tests a plurality of standard samples with preset concentration values through the specific protein detection module 13, and can implement multi-point calibration to obtain a calibration curve.

Other calibration curves disclosed herein (e.g., the second calibration curve, the third calibration curve, the fourth calibration curve, the fifth calibration curve, and the sixth calibration curve) may employ the multi-point calibration.

In one embodiment, when the sample analyzer 10 swipes the reagent card, the sample analyzer 10 imports a plurality of calibration curves from the reagent card to store the plurality of calibration curves to the storage module 15. Therefore, the sample analyzer 10 can directly obtain a plurality of calibration curves from the reagent card without performing multi-point calibration, thereby reducing the consumption of calibration reagents and improving the use experience of users.

Referring to fig. 5, fig. 5 is a schematic structural diagram of a third embodiment of the sample analyzer of the present application. The sample analyzer 10 of this embodiment includes a sample module 11, a reagent supplying module 12, at least one specific protein detecting module 13, a control module 14, a storage module 15 and a display module 16, and the sample module 11, the reagent supplying module 12, the control module 14, the storage module 15 and the display module 16 are the same as those disclosed in the above embodiments, and are not described herein again.

The sample analyzer 10 of the present embodiment includes four specific protein detection modules 13, that is, at least one specific protein detection module 13 includes a specific protein detection module 133, a specific protein detection module 134, a specific protein detection module 135, and a specific protein detection module 136.

In one embodiment, four specific protein detection modules 13 are used to perform a first specific protein detection item and a second specific protein detection item on the sample.

The control module 14 is configured to select two specific protein detection modules 13 to calibrate a first specific protein detection item, calibrate the remaining two specific protein detection modules 13 to a second specific protein detection item to obtain a first calibration curve and a second calibration curve, and store the first calibration curve and the second calibration curve in the storage module 15.

Specifically, when the control module 14 selects the specific protein detection module 133 and the specific protein detection module 134 to perform the first specific protein detection item detection on the sample, and selects the specific protein detection module 135 and the specific protein detection module 136 to perform the second specific protein detection item detection on the sample, the control module 14 respectively calibrates the specific protein detection module 133 and the specific protein detection module 134 on the first specific protein detection item to obtain a first calibration curve of the specific protein detection module 133 and a first calibration curve of the specific protein detection module 134, that is, a first calibration curve; the control module 14 scales the specific protein detection module 135 and the specific protein detection module 136 for the second specific protein detection item, respectively, to obtain a second scaling curve of the specific protein detection module 135 and a second scaling curve of the specific protein detection module 136, i.e. a second scaling curve. The control module 14 further stores the first calibration curve of the specific protein detection module 133, the first calibration curve of the specific protein detection module 134, the second calibration curve of the specific protein detection module 135, and the second calibration curve of the specific protein detection module 136 in the storage module 15.

When the sample analyzer 10 selects the detection mode, the control module 14 selects the specific protein detection module 133 and the specific protein detection module 134 to perform a first specific protein detection item on the sample, and selects the specific protein detection module 135 and the specific protein detection module 136 to perform a second specific protein detection item on the sample. The control module 14 obtains the first calibration curve of the specific protein detection module 133, the first calibration curve of the specific protein detection module 134, the second calibration curve of the specific protein detection module 135, and the second calibration curve of the specific protein detection module 136 from the storage module 15.

The control module 14 detects a first specific protein detection item on the sample through the specific protein detection module 133, and obtains a first detection result of the specific protein detection module 133 based on the first calibration curve of the specific protein detection module 133; the specific protein detection module 134 detects a first specific protein detection item for the sample, and obtains a first detection result of the specific protein detection module 134 based on the first calibration curve of the specific protein detection module 134. The control module 14 performs a second specific protein detection item on the sample through the specific protein detection module 135, and obtains a second detection result of the specific protein detection module 135 based on a second calibration curve of the specific protein detection module 135; the specific protein detection module 136 detects a second specific protein detection item for the sample, and a second detection result of the specific protein detection module 136 is obtained based on a second calibration curve of the specific protein detection module 136.

Alternatively, the control module 14 controls the specific protein detection module 133, the specific protein detection module 134, the specific protein detection module 135 and the specific protein detection module 136 to calibrate the first specific protein detection item and the second specific protein detection item, respectively, and stores the obtained first calibration curve and the second calibration curve of the specific protein detection module 133, the obtained first calibration curve and the second calibration curve of the specific protein detection module 134, the obtained first calibration curve and the second calibration curve of the specific protein detection module 135, and the obtained first calibration curve and the obtained second calibration curve of the specific protein detection module 136 in the storage module 15. When the control module 14 selects the specific protein detection module 133 and the specific protein detection module 134 to perform the second specific protein detection item on the sample, and selects the specific protein detection module 135 and the specific protein detection module 136 to perform the first specific protein detection item on the sample, the control module 14 obtains the second calibration curve of the specific protein detection module 133, the second calibration curve of the specific protein detection module 134, the first calibration curve of the specific protein detection module 135, and the first calibration curve of the specific protein detection module 136 from the storage module 15.

Or, the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, and selects the specific protein detection module 133 to perform a second specific protein detection item on the sample; the control module 14 acquires the first and second calibration curves of the specific protein detection module 133 from the storage module 15.

Alternatively, the control module 14 controls the specific protein detection module 133 (or the specific protein detection module 134, the specific protein detection module 135, and the specific protein detection module 136) to calibrate the first specific protein detection item and the second specific protein detection item, respectively, and stores the obtained first calibration curve and the second calibration curve in the storage module 15. When the control module 14 selects the specific protein detection module 133 and the specific protein detection module 134 to perform the second specific protein detection item detection on the sample, and selects the specific protein detection module 135 and the specific protein detection module 136 to perform the first specific protein detection item detection on the sample, the control module 14 obtains the second calibration curve from the storage module 15 as the calibration curve of the specific protein detection module 133 and the specific protein detection module 134, and selects the first calibration curve as the calibration curve of the specific protein detection module 135 and the specific protein detection module 136.

Or, the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, and selects the specific protein detection module 133 to perform a second specific protein detection item on the sample; the control module 14 retrieves the first and second calibration curves from the memory module 15.

Optionally, the display module 16 is configured to display the first detection result of the specific protein detection module 133, the first detection result of the specific protein detection module 134, the second detection result of the specific protein detection module 135, and the second detection result of the specific protein detection module 136 on a display interface.

In this embodiment, the four specific protein detection modules 13 of the sample analyzer 10 perform two specific protein detection items on the sample, and the sample analyzer 10 directly calls the corresponding calibration curve from the storage module 15 through the control module 14 during mode switching, so that recalibration is not required, calibration flow time is shortened, consumption of calibration reagents is reduced, and user experience is improved.

In one embodiment, the four protein-specific detection modules 13 of the sample analyzer 10 are used to perform a first protein-specific detection item, a second protein-specific detection item, and a third protein-specific detection item on the sample.

The control module 14 is configured to select two specific protein detection modules 13 to calibrate a first specific protein detection item, sequentially calibrate a second specific protein detection item and a third specific protein detection item with the remaining two specific protein detection modules 13 to obtain a first calibration curve, a second calibration curve and a third calibration curve, and store the first calibration curve, the second calibration curve and the third calibration curve in the storage module 15.

Specifically, when the control module 14 selects the specific protein detection module 133 and the specific protein detection module 134 to perform a first specific protein detection item on the sample, selects the specific protein detection module 135 to perform a second specific protein detection item on the sample, and selects the specific protein detection module 136 to perform a third specific protein detection item on the sample, the control module 14 respectively calibrates the specific protein detection module 133 and the specific protein detection module 134 on the first specific protein detection item to obtain a first calibration curve of the specific protein detection module 133 and a first calibration curve of the specific protein detection module 134, that is, a first calibration curve; the control module 14 calibrates the specific protein detection module 135 to the second specific protein detection item to obtain a second calibration curve, i.e. a second calibration curve, of the specific protein detection module 135; the control module 14 scales the specific protein detecting module 136 for the third specific protein detecting item to obtain a third scaling curve of the specific protein detecting module 136, i.e. a third scaling curve. The control module 14 further stores the first calibration curve of the specific protein detection module 133, the first calibration curve of the specific protein detection module 134, the second calibration curve of the specific protein detection module 135, and the third calibration curve of the specific protein detection module 136 in the storage module 15.

When the sample analyzer 10 selects the detection mode, the control module 14 selects the specific protein detection module 133 and the specific protein detection module 134 to perform a first specific protein detection item on the sample, selects the specific protein detection module 135 to perform a second specific protein detection item on the sample, and selects the specific protein detection module 136 to perform a third specific protein detection item on the sample. The control module 14 obtains the first calibration curve of the specific protein detection module 133, the first calibration curve of the specific protein detection module 134, the second calibration curve of the specific protein detection module 135, and the third calibration curve of the specific protein detection module 136 from the storage module 15.

The control module 14 detects a first specific protein detection item on the sample through the specific protein detection module 133, and obtains a first detection result of the specific protein detection module 133 based on the first calibration curve of the specific protein detection module 133; the specific protein detection module 134 detects a first specific protein detection item for the sample, and obtains a first detection result of the specific protein detection module 134 based on the first calibration curve of the specific protein detection module 134. The control module 14 performs a second specific protein detection item on the sample through the specific protein detection module 135, and obtains a second detection result of the specific protein detection module 135 based on a second calibration curve of the specific protein detection module 135; the specific protein detection module 136 detects a third specific protein detection item for the sample, and obtains a third detection result of the specific protein detection module 136 based on the third calibration curve of the specific protein detection module 136.

Optionally, the control module 14 controls the specific protein detection module 133, the specific protein detection module 134, the specific protein detection module 135 and the specific protein detection module 136 to calibrate the first specific protein detection item, the second specific protein detection item and the third specific protein detection item, respectively, and stores the obtained first calibration curve, the second calibration curve and the third calibration curve of the specific protein detection module 133, the first calibration curve, the second calibration curve and the third calibration curve of the specific protein detection module 134, the first calibration curve, the second calibration curve and the third calibration curve of the specific protein detection module 135, and the first calibration curve, the second calibration curve and the third calibration curve of the specific protein detection module 136 to the storage module 15. When the control module 14 selects the specific protein detection module 133 and the specific protein detection module 134 to perform a first specific protein detection item on the sample, selects the specific protein detection module 135 to perform a second specific protein detection item on the sample, and selects the specific protein detection module 136 to perform a third specific protein detection item on the sample, the control module 14 obtains the first calibration curve of the specific protein detection module 133, the first calibration curve of the specific protein detection module 134, the second calibration curve of the specific protein detection module 135, and the third calibration curve of the specific protein detection module 136 from the storage module 15.

Or, the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 133 to perform a second specific protein detection item on the sample, and selects the specific protein detection module 133 to perform a third specific protein detection item on the sample; the control module 14 acquires the first calibration curve, the second calibration curve and the third calibration curve of the specific protein detecting module 133 from the storage module 15.

Optionally, the control module 14 controls the specific protein detection module 133 (or the specific protein detection module 134, the specific protein detection module 135, and the specific protein detection module 136) to calibrate the first specific protein detection item, the second specific protein detection item, and the third specific protein detection item, respectively, and stores the obtained first calibration curve, the second calibration curve, and the third calibration curve in the storage module 15. When the control module 14 selects the specific protein detection module 133 and the specific protein detection module 134 to perform a first specific protein detection item on the sample, selects the specific protein detection module 135 to perform a second specific protein detection item on the sample, and selects the specific protein detection module 136 to perform a third specific protein detection item on the sample, the control module 14 obtains the first calibration curve from the storage module 15 as the calibration curve of the specific protein detection module 133 and the specific protein detection module 134, obtains the second calibration curve as the calibration curve of the specific protein detection module 135, and obtains the third calibration curve as the calibration curve of the specific protein detection module 136.

Or, the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 133 to perform a second specific protein detection item on the sample, and selects the specific protein detection module 133 to perform a third specific protein detection item on the sample; the control module 14 obtains the first, second and third calibration curves from the storage module 15.

Optionally, the display module 16 is configured to display the first detection result of the specific protein detection module 133, the first detection result of the specific protein detection module 134, the second detection result of the specific protein detection module 135, and the third detection result of the specific protein detection module 136 on a display interface.

In this embodiment, the four specific protein detection modules 13 of the sample analyzer 10 perform three specific protein detection items on the sample, and the sample analyzer 10 directly calls the corresponding calibration curve from the storage module 15 through the control module 14 during mode switching, so that recalibration is not required, calibration flow time is shortened, consumption of calibration reagents is reduced, and user experience is improved.

In one embodiment, the four protein-specific detection modules 13 of the sample analyzer 10 are used for performing a first protein-specific detection item, a second protein-specific detection item, a third protein-specific detection item, and a fourth protein-specific detection item on the sample.

The control module 14 selects different specific protein detection modules from the four specific protein detection modules 13, sequentially scales the first specific protein detection item, the second specific protein detection item, the third specific protein detection item, and the fourth specific protein detection item to obtain a first scaling curve, a second scaling curve, a third scaling curve, and a fourth scaling curve, and stores the first scaling curve, the second scaling curve, the third scaling curve, and the fourth scaling curve in the storage module 15.

Specifically, when the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 134 to perform a second specific protein detection item on the sample, selects the specific protein detection module 135 to perform a third specific protein detection item on the sample, and selects the specific protein detection module 136 to perform a fourth specific protein detection item on the sample, the control module 14 calibrates the specific protein detection module 133 on the first specific protein detection item to obtain a first calibration curve, i.e., a first calibration curve, of the specific protein detection module 133; the control module 14 calibrates the specific protein detection module 134 on the second specific protein detection item to obtain a second calibration curve, i.e. a second calibration curve, of the specific protein detection module 134; the control module 14 calibrates the specific protein detection module 135 in the third specific protein detection item to obtain a third calibration curve, i.e. a third calibration curve, of the specific protein detection module 135; the control module 14 scales the fourth specific protein detection item of the specific protein detection module 136 to obtain a fourth scaling curve, i.e. a fourth scaling curve, of the specific protein detection module 136. The control module 14 further stores the first calibration curve of the specific protein detection module 133, the second calibration curve of the specific protein detection module 134, the third calibration curve of the specific protein detection module 135 and the fourth calibration curve of the specific protein detection module 136 in the storage module 15.

When the sample analyzer 10 selects the detection mode, the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 134 to perform a second specific protein detection item on the sample, selects the specific protein detection module 135 to perform a third specific protein detection item on the sample, and selects the specific protein detection module 136 to perform a fourth specific protein detection item on the sample. The control module 14 obtains the first calibration curve of the specific protein detection module 133, the second calibration curve of the specific protein detection module 134, the third calibration curve of the specific protein detection module 135, and the fourth calibration curve of the specific protein detection module 136 from the storage module 15.

The control module 14 detects a first specific protein detection item on the sample through the specific protein detection module 133, and obtains a first detection result of the specific protein detection module 133 based on the first calibration curve of the specific protein detection module 133; the specific protein detection module 134 detects a second specific protein detection item for the sample, and obtains a second detection result of the specific protein detection module 134 based on the second calibration curve of the specific protein detection module 134. The control module 14 performs detection of a third specific protein detection item on the sample through the specific protein detection module 135, and obtains a third detection result of the specific protein detection module 135 based on a third calibration curve of the specific protein detection module 135; the specific protein detection module 136 detects a fourth specific protein detection item for the sample, and a fourth detection result of the specific protein detection module 136 is obtained based on the fourth calibration curve of the specific protein detection module 136.

Optionally, the control module 14 controls the specific protein detection module 133, the specific protein detection module 134, the specific protein detection module 135 and the specific protein detection module 136 to calibrate the first specific protein detection item, the second specific protein detection item, the third specific protein detection item and the fourth specific protein detection item, respectively, and stores the obtained first calibration curve, second calibration curve, third calibration curve and fourth calibration curve of the specific protein detection module 133, the first calibration curve, second calibration curve, third calibration curve and fourth calibration curve of the specific protein detection module 134, the first calibration curve, second calibration curve, third calibration curve and fourth calibration curve of the specific protein detection module 135, the first calibration curve, second calibration curve, third calibration curve and fourth calibration curve of the specific protein detection module 136, and the first calibration curve, second calibration curve, third calibration curve and fourth calibration curve of the specific protein detection module 136 in the storage module 15. When the control module 14 selects the specific protein detection module 133 to perform the first specific protein detection item on the sample, selects the specific protein detection module 134 to perform the second specific protein detection item on the sample, selects the specific protein detection module 135 to perform the third specific protein detection item on the sample, and selects the specific protein detection module 136 to perform the fourth specific protein detection item on the sample, the control module 14 obtains the first calibration curve of the specific protein detection module 133, the second calibration curve of the specific protein detection module 134, the third calibration curve of the specific protein detection module 135, and the fourth calibration curve of the specific protein detection module 136 from the storage module 15.

Or, the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 133 to perform a second specific protein detection item on the sample, selects the specific protein detection module 133 to perform a third specific protein detection item on the sample, and selects the specific protein detection module 133 to perform a fourth specific protein detection item on the sample; the control module 14 acquires the first, second, third and fourth calibration curves of the specific protein detecting module 133 from the storage module 15.

Optionally, the control module 14 controls the specific protein detecting module 133 (or the specific protein detecting module 134, the specific protein detecting module 135, and the specific protein detecting module 136) to calibrate the first specific protein detecting item, the second specific protein detecting item, the third specific protein detecting item, and the fourth specific protein detecting item, respectively, and stores the obtained first calibration curve, the second calibration curve, the third calibration curve, and the fourth calibration curve in the storage module 15. When the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 134 to perform a second specific protein detection item on the sample, selects the specific protein detection module 135 to perform a third specific protein detection item on the sample, and selects the specific protein detection module 136 to perform a fourth specific protein detection item on the sample, the control module 14 obtains the first calibration curve from the storage module 15 as the specific protein detection module 133, obtains the second calibration curve as the calibration curve of the specific protein detection module 134, obtains the third calibration curve as the calibration curve of the specific protein detection module 135, and obtains the fourth calibration curve as the calibration curve of the specific protein detection module 136.

Or, the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 133 to perform a second specific protein detection item on the sample, selects the specific protein detection module 133 to perform a third specific protein detection item on the sample, and selects the specific protein detection module 133 to perform a fourth specific protein detection item on the sample; the control module 14 obtains the first, second, third and fourth calibration curves from the storage module 15.

Optionally, the display module 16 is configured to display the first detection result of the specific protein detection module 133, the second detection result of the specific protein detection module 134, the third detection result of the specific protein detection module 135, and the fourth detection result of the specific protein detection module 136 on a display interface.

In this embodiment, the four specific protein detection modules 13 of the sample analyzer 10 perform four specific protein detection items on the sample, and the control module 14 directly calls the corresponding calibration curve from the storage module 15, so that recalibration is not required, the calibration flow time is shortened, the consumption of the calibration reagent is reduced, and the use experience of the user is improved.

In one embodiment, the four specific protein detection modules 13 of the sample analyzer 10 are used for performing a first specific protein detection item, a second specific protein detection item, a third specific protein detection item, a fourth specific protein detection item, a fifth specific protein detection item, and a sixth specific protein detection item on the sample.

The control module 14 selects different specific protein detection modules from the four specific protein detection modules 13, sequentially scales the first specific protein detection item, the second specific protein detection item, the third specific protein detection item, the fourth specific protein detection item, the fifth specific protein detection item, and the sixth specific protein detection item to obtain a first scaling curve, a second scaling curve, a third scaling curve, a fourth scaling curve, a fifth scaling curve, and a sixth scaling curve, and stores the first scaling curve, the second scaling curve, the third scaling curve, the fourth scaling curve, the fifth scaling curve, and the sixth scaling curve in the storage module 15.

Specifically, when the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 134 to perform a second specific protein detection item on the sample, selects the specific protein detection module 135 to perform a third specific protein detection item on the sample, selects the specific protein detection module 136 to perform a fourth specific protein detection item on the sample, selects the specific protein detection module 133 to perform a fifth specific protein detection item on the sample, and selects the specific protein detection module 134 to perform a sixth specific protein detection item on the sample, the control module 14 respectively calibrates the specific protein detection module 133 on the first specific protein detection item and the fifth specific protein detection item to obtain a first calibration curve and a fifth calibration curve, that is, a first calibration curve and a fifth calibration curve, of the specific protein detection module 133; the control module 14 calibrates the specific protein detection module 134 in the second specific protein detection item and the sixth specific protein detection item, respectively, to obtain a second calibration curve and a sixth calibration curve of the specific protein detection module 134, that is, the second calibration curve and the sixth calibration curve; the control module 14 calibrates the specific protein detection module 135 in the third specific protein detection item to obtain a third calibration curve, i.e. a third calibration curve, of the specific protein detection module 135; the control module 14 scales the fourth specific protein detection item of the specific protein detection module 136 to obtain a fourth scaling curve, i.e. a fourth scaling curve, of the specific protein detection module 136.

When the sample analyzer 10 detects a sample, the control module 14 performs a first specific protein detection item detection on the sample through the specific protein detection module 133, and obtains a first detection result of the specific protein detection module 133 based on a first calibration curve of the specific protein detection module 133; the specific protein detection module 134 detects a second specific protein detection item for the sample, and obtains a second detection result of the specific protein detection module 134 based on the second calibration curve of the specific protein detection module 134. The control module 14 performs detection of a third specific protein detection item on the sample through the specific protein detection module 135, and obtains a third detection result of the specific protein detection module 135 based on a third calibration curve of the specific protein detection module 135; and detecting a fourth specific protein detection item on the sample through the specific protein detection module 136, and obtaining a fourth detection result of the specific protein detection module 136 based on the fourth calibration curve of the specific protein detection module 136. The control module 14 performs a fifth specific protein detection item on the sample through the specific protein detection module 133, and obtains a fifth detection result of the specific protein detection module 133 based on a fifth calibration curve of the specific protein detection module 133; the specific protein detection module 134 detects a sixth specific protein detection item for the sample, and obtains a sixth detection result of the specific protein detection module 134 based on a sixth calibration curve of the specific protein detection module 134.

Optionally, the control module 14 controls the specific protein detection module 133, the specific protein detection module 134, the specific protein detection module 135 and the specific protein detection module 136 to respectively calibrate the first specific protein detection item, the second specific protein detection item, the third specific protein detection item, the fourth specific protein detection item, the fifth specific protein detection item and the sixth specific protein detection item, and store the first calibration curve, the second calibration curve, the third calibration curve, the fourth calibration curve, the fifth calibration curve and the sixth calibration curve of the obtained specific protein detection module 133, the first calibration curve, the second calibration curve, the third calibration curve, the fifth calibration curve and the sixth calibration curve of the obtained specific protein detection module 134, the first calibration curve, the second calibration curve, the third calibration curve and the sixth calibration curve of the obtained specific protein detection module 136, the first calibration curve, the second calibration curve, the fourth calibration curve, the fifth calibration curve and the sixth calibration curve of the obtained specific protein detection module 135, the first calibration curve, the second calibration curve, the fourth calibration curve, the third calibration curve, the fourth calibration curve, the fifth calibration curve and the sixth calibration curve of the obtained specific protein detection module 136, and the first calibration curve, the second calibration curve, the third calibration curve, the fourth calibration curve and the sixth calibration curve of the obtained specific protein detection module 136, and the specific protein detection module 15. When the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 134 to perform a second specific protein detection item on the sample, selects the specific protein detection module 135 to perform a third specific protein detection item on the sample, selects the specific protein detection module 136 to perform a fourth specific protein detection item on the sample, selects the specific protein detection module 133 to perform a fifth specific protein detection item on the sample, and selects the specific protein detection module 134 to perform a sixth specific protein detection item on the sample, the control module 14 obtains the first calibration curve and the fifth calibration curve of the specific protein detection module 133, the second calibration curve and the sixth calibration curve of the specific protein detection module 134, the third calibration curve of the specific protein detection module 135, and the fourth calibration curve of the specific protein detection module 136 from the storage module 15.

Or, the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 133 to perform a second specific protein detection item on the sample, selects the specific protein detection module 133 to perform a third specific protein detection item on the sample, selects the specific protein detection module 133 to perform a fourth specific protein detection item on the sample, selects the specific protein detection module 133 to perform a fifth specific protein detection item on the sample, and selects the specific protein detection module 133 to perform a sixth specific protein detection item on the sample; the control module 14 acquires the first, second, third, fourth, fifth and sixth calibration curves of the specific protein detecting module 133 from the storage module 15.

Optionally, the control module 14 controls the specific protein detecting module 133 (or the specific protein detecting module 134, the specific protein detecting module 135, and the specific protein detecting module 136) to calibrate the first specific protein detecting item, the second specific protein detecting item, the third specific protein detecting item, the fourth specific protein detecting item, the fifth specific protein detecting item, and the sixth specific protein detecting item, respectively, and store the obtained first calibration curve, the second calibration curve, the third calibration curve, the fourth calibration curve, the fifth calibration curve, and the sixth calibration curve in the storage module 15. When the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 134 to perform a second specific protein detection item on the sample, selects the specific protein detection module 135 to perform a third specific protein detection item on the sample, selects the specific protein detection module 136 to perform a fourth specific protein detection item on the sample, selects the specific protein detection module 133 to perform a fifth specific protein detection item on the sample, and selects the specific protein detection module 134 to perform a sixth specific protein detection item on the sample, the control module 14 obtains the first calibration curve, the second calibration curve, the third calibration curve, the fourth calibration curve, the fifth calibration curve, and the sixth calibration curve from the storage module 15.

Or, the control module 14 selects the specific protein detection module 133 to perform a first specific protein detection item on the sample, selects the specific protein detection module 133 to perform a second specific protein detection item on the sample, selects the specific protein detection module 133 to perform a third specific protein detection item on the sample, selects the specific protein detection module 133 to perform a fourth specific protein detection item on the sample, selects the specific protein detection module 133 to perform a fifth specific protein detection item on the sample, and selects the specific protein detection module 133 to perform a sixth specific protein detection item on the sample; the control module 14 obtains the first, second, third, fourth, fifth, and sixth calibration curves from the storage module 15.

Optionally, the display module 16 is configured to display the first detection result of the specific protein detection module 133, the second detection result of the specific protein detection module 134, the third detection result of the specific protein detection module 135, the fourth detection result of the specific protein detection module 136, the fifth detection result of the specific protein detection module 133, and the sixth detection result of the specific protein detection module 134 on a display interface.

In this embodiment, the four specific protein detection modules 13 of the sample analyzer 10 perform six specific protein detection items on the sample, and the control module 14 directly calls the corresponding calibration curve from the storage module 15, so that re-calibration is not required, the consumption of the calibration reagent is reduced, and the use experience of the user is improved.

Referring to fig. 6, fig. 6 is a schematic structural diagram of a fourth embodiment of the sample analyzer of the present application. The sample analyzer 10 of this embodiment includes a sample module 11, a reagent supply module 12, at least one specific protein detection module 13, a control module 14, a storage module 15 and a blood routine detection module 17, wherein the sample module 11, the reagent supply module 12, the control module 14 and the storage module 15 are the same as those disclosed in the above embodiments, and are not described herein again.

The blood routine detecting module 17 is used for performing blood routine detection on the sample, wherein the blood routine detection includes WBC (white blood cell) detection, HGB (Hemoglobin) detection, RBC (red blood cell) detection, DIFF (differential, white blood cell five classification) detection or RET (reticulocyte) detection.

The sample analyzer 10 of the embodiment is provided with a blood routine detection module 17, and the blood routine detection module 17 is used for performing blood routine detection on a sample, so that an integrated machine of blood routine detection and specific protein detection is realized, and the use experience of a user is improved.

Referring to fig. 7, fig. 7 is a schematic flow chart of a first embodiment of a detection method of the sample analyzer of the present application. The detection method of the present embodiment is applied to the sample analyzer 10 disclosed in the above embodiment, wherein the detection method includes the following steps:

s701: the plurality of calibration curves is stored to the storage module 15.

The calibration curves correspond to a plurality of specific protein detection items one by one, that is, each specific protein detection item in the specific protein detection module 13 corresponds to one calibration curve.

Optionally, the control module 14 scales all the specific protein detection items of each specific protein detection module 13 to obtain a plurality of scaling curves, and stores the plurality of scaling curves in the storage module 15, so that the control module 14 can directly call the scaling curves.

In other embodiments, when a plurality of specific protein detection modules 13 are used to detect the same specific protein detection item on a sample, the detection of the specific protein detection item can correspond to a calibration curve. Therefore, the control module 14 scales the same specific protein detection item of all the specific protein detection modules 13 to obtain a scaling curve, and stores the scaling curve in the storage module 15.

S702: when the specific protein detection module 13 detects a first specific protein detection item on the sample, a first calibration curve corresponding to the first specific protein detection item is obtained from the plurality of calibration curves, and a first detection result is obtained based on the first calibration curve.

When the specific protein detection module 13 is configured to detect a first specific protein detection item on a sample, the control module 14 is configured to obtain a first calibration curve corresponding to the first specific protein detection item from the multiple calibration curves of the storage module 15, and obtain a first detection result based on the first calibration curve. That is, the control module 14 controls the specific protein detection module 13 to perform the detection of the first specific protein detection item on the sample, and the control module 14 obtains the first calibration curve from the plurality of calibration curves and obtains a first detection result based on the first calibration curve, where the first detection result includes a parameter of the first specific protein detection item.

In this embodiment, when the specific protein detection module 13 performs a first specific protein detection item on a sample, a first calibration curve corresponding to the first specific protein detection item is obtained from a plurality of calibration curves, and a first detection result is obtained based on the first calibration curve; therefore, when the mode of the sample analyzer 10 is switched, the control module 14 obtains the corresponding calibration curves from the plurality of calibration curves stored in the storage module 15, re-calibration is not needed, the calibration flow time is shortened, the consumption of the calibration reagent is reduced, and the use experience of a user is improved.

In an embodiment, before step S701, the detection method further includes: all the specific protein detection items of each of the specific protein detection modules 13 are scaled to obtain the plurality of scaling curves, and the plurality of scaling curves are stored in the storage module 15.

In other embodiments, before step S701, the detection method further includes: and calibrating the same specific protein detection item of the specific protein detection module 13 to obtain a calibration curve, and storing the calibration curve in the storage module 15.

Referring to fig. 8, fig. 8 is a schematic flow chart of a second embodiment of a detection method of the sample analyzer of the present application. The detection method of the present embodiment is applied to the sample analyzer 10 disclosed in the above embodiment, wherein the detection method includes the following steps:

s801: and controlling the specific protein detection module 13 to switch from the second specific protein detection item to the first specific protein detection item.

When the sample analyzer 10 switches the detection mode, the control module 14 controls the specific protein detection module 13 to switch from the second specific protein detection item to the first specific protein detection item.

S802: it is determined whether the memory module 15 includes a first calibration curve corresponding to the first specific protein assay.

After the control module 14 controls the specific protein detection module 13 to switch from the second specific protein detection item to the first specific protein detection item, the control module 14 determines whether the storage module 15 includes a first calibration curve corresponding to the first specific protein detection item; if not, the process goes to step S803; if yes, go to step S804.

S803: if not, the first specific protein detection item is calibrated to obtain a first calibration curve, and the first calibration curve is stored in the storage module 15.

If not, the control module 14 controls the specific protein detection module 13 to calibrate the first specific protein detection item to obtain a first calibration curve, and stores the first calibration curve in the storage module 15. The control module 14 further controls the specific protein detection module 13 to perform a first specific protein detection item on the sample, and obtain a first detection result based on the first calibration curve.

S804: if yes, a first calibration curve corresponding to the first specific protein detection item is obtained from the storage module 15, and a first detection result is obtained based on the first calibration curve.

Step S804 is the same as step S702, and is not described herein again.

The embodiment determines whether the storage module 15 includes a first calibration curve corresponding to a first specific protein detection item; if not, calibrating the first specific protein detection item to obtain a first calibration curve; therefore, the first calibration curve corresponding to the first specific protein detection item can be obtained, and the specific protein detection module 13 can perform the first specific protein detection item on the sample.

In addition, compared with the calibration of all the specific protein detection items of each specific protein detection module 13 in the detection method of the first embodiment, this embodiment does not need to calibrate all the specific protein detection items, and can reduce the consumption of the calibration reagent and improve the user experience.

Referring to fig. 9, fig. 9 is a schematic flow chart of a third embodiment of a detection method of the sample analyzer of the present application. The detection method of the present embodiment is applied to the sample analyzer 10 disclosed in the above embodiment, wherein the detection method includes the following steps:

s901: and measuring each specific protein detection module 13 for multiple times by using a plurality of standard samples with preset concentration values respectively to obtain a measurement result.

The control module 14 performs multiple measurements on each specific protein detection module 13 by using a plurality of standard samples with preset concentration values, respectively, to obtain measurement results. The number of the standard samples of the preset concentration value may be 2, 4, 6, or 8, etc.

S902: the measurement results are used to obtain a calibration curve and the calibration curve is stored in the storage module 15.

The control module 14 uses the measurement results to obtain a calibration curve and stores the calibration curve in the storage module 15. That is, the control module 14 obtains a calibration curve using the measurement results and a plurality of preset concentration values.

The calibration curves (e.g., the first calibration curve, the second calibration curve, the third calibration curve, the fourth calibration curve, the fifth calibration curve, and the sixth calibration curve) disclosed in the present application can all obtain corresponding calibration curves through steps S901 and S902.

S903: the corresponding specific protein detection module 13 is selected according to the detection mode selected by the sample analyzer 10.

The control module 14 selects the corresponding specific protein detection module 13 according to the detection mode selected by the sample analyzer 10.

In one embodiment, the four specific protein detection modules 13 of the sample analyzer 10 are configured to perform a first specific protein detection item and a second specific protein detection item on the sample, and the control module 14 is configured to select two specific protein detection modules 13 to calibrate the first specific protein detection item, calibrate the remaining two specific protein detection modules 13 to obtain a first calibration curve and a second calibration curve, and store the first calibration curve and the second calibration curve in the storage module 15.

In one embodiment, the four protein-specific detection modules 13 of the sample analyzer 10 are used to perform a first protein-specific detection item, a second protein-specific detection item, and a third protein-specific detection item on the sample. The control module 14 is configured to select two specific protein detection modules 13 to calibrate a first specific protein detection item, sequentially calibrate a second specific protein detection item and a third specific protein detection item with the remaining two specific protein detection modules 13 to obtain a first calibration curve, a second calibration curve and a third calibration curve, and store the first calibration curve, the second calibration curve and the third calibration curve in the storage module 15.

In one embodiment, the four protein-specific detection modules 13 of the sample analyzer 10 are used for performing a first protein-specific detection item, a second protein-specific detection item, a third protein-specific detection item, and a fourth protein-specific detection item on the sample. The control module 14 selects different specific protein detection modules from the four specific protein detection modules 13, sequentially scales the first specific protein detection item, the second specific protein detection item, the third specific protein detection item, and the fourth specific protein detection item to obtain a first scaling curve, a second scaling curve, a third scaling curve, and a fourth scaling curve, and stores the first scaling curve, the second scaling curve, the third scaling curve, and the fourth scaling curve in the storage module 15.

Referring to fig. 10, fig. 10 is a schematic flow chart of a fourth embodiment of a detection method of the sample analyzer of the present application. The detection method of the present embodiment is applied to the sample analyzer 10 disclosed in the above embodiment, wherein the detection method includes the following steps:

s101: and measuring the single specific protein detection module 13 for multiple times by using the standard samples with the plurality of preset concentration values corresponding to different specific protein detection items respectively to obtain a measurement result.

The control module 14 measures a plurality of times for a single specific protein detection module 13 by using a plurality of standard samples with preset concentration values corresponding to different specific protein detection items, respectively, to obtain a measurement result. The number of the standard samples of the preset concentration value may be 2, 4, 6, or 8, etc.

S102: a plurality of calibration curves corresponding to the specific protein test items are obtained using the measurement results, and the plurality of calibration curves are stored in the storage module 15.

The control module 14 obtains a plurality of calibration curves corresponding to the specific protein detection items using the measurement results, and stores the plurality of calibration curves in the storage module 15. That is, the control module 14 obtains a plurality of calibration curves corresponding to the specific protein detection items by using the measurement results and the plurality of preset concentration values.

S103: the corresponding specific protein detection module 13 is selected according to the detection mode selected by the sample analyzer 10.

The control module 14 selects the corresponding specific protein detection module 13 according to the detection mode selected by the sample analyzer 10. In one embodiment, the four specific protein detection modules 13 of the sample analyzer 10 are used for performing a first specific protein detection item, a second specific protein detection item, a third specific protein detection item, a fourth specific protein detection item, a fifth specific protein detection item and a sixth specific protein detection item on the sample. The control module 14 selects different specific protein detection modules from the four specific protein detection modules 13, sequentially scales the first specific protein detection item, the second specific protein detection item, the third specific protein detection item, the fourth specific protein detection item, the fifth specific protein detection item, and the sixth specific protein detection item to obtain a first scaling curve, a second scaling curve, a third scaling curve, a fourth scaling curve, a fifth scaling curve, and a sixth scaling curve, and stores the first scaling curve, the second scaling curve, the third scaling curve, the fourth scaling curve, the fifth scaling curve, and the sixth scaling curve in the storage module 15.

Optionally, the control module 14 tests a plurality of standard samples with preset concentration values through the specific protein detection module 13 to obtain measured values. The control module 14 obtains a first calibration curve based on a regression curve between the preset concentration value and the measured value. The number of the standard samples of the preset concentration value may be 2, 4, 6, or 8, etc. Therefore, the control module 14 tests a plurality of standard samples with preset concentration values through the specific protein detection module 13, and can realize multi-point calibration to obtain a calibration curve. Other calibration curves disclosed herein (e.g., the second calibration curve, the third calibration curve, the fourth calibration curve, the fifth calibration curve, and the sixth calibration curve) may employ the multi-point calibration.

Alternatively, when the sample analyzer 10 swipes the reagent card, a plurality of calibration curves are imported from the reagent card to store the plurality of calibration curves in the storage module 15. Therefore, the sample analyzer 10 can directly obtain a plurality of calibration curves from the reagent card without performing multi-point calibration, thereby reducing the consumption of calibration reagents and improving the use experience of users.

In the several embodiments provided in the present application, it should be understood that the disclosed apparatus may be implemented in other manners. For example, the above-described device embodiments are merely illustrative, and for example, the division of the modules or units is only one logical division, and other divisions may be realized in practice, for example, a plurality of units or components may be combined or integrated into another system, or some features may be omitted, or not executed.

The units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the embodiment.

In addition, functional units in the embodiments of the present application may be integrated into one processing unit, or each unit may exist alone physically, or two or more units may be integrated into one unit. The integrated unit may be implemented in the form of hardware, or may also be implemented in the form of a software functional unit.

The above description is only for the purpose of illustrating embodiments of the present application and is not intended to limit the scope of the present application, and all modifications of equivalent structures and equivalent processes, which are made according to the content of the present specification and the accompanying drawings, or which are directly or indirectly applied to other related technical fields, are also included in the scope of the present application.

Claims

1. A sample analyzer, comprising:

a sample module for collecting and distributing samples;

a reagent supply module for supplying a reagent;

at least one specific protein detection module for detecting a plurality of specific protein detection items on the sample;

the control module is respectively connected with the sample module, the reagent supply module, the specific protein detection module and the storage module and is used for storing a plurality of calibration curves into the storage module;

when the specific protein detection module detects a first specific protein detection item on the sample, the control module obtains a first calibration curve corresponding to the first specific protein detection item from the calibration curves, and obtains a first detection result based on the first calibration curve.

2. The sample analyzer of claim 1, wherein each of the protein-specific detection modules includes a reaction cell, the sample module distributes the sample to the reaction cell, the reagent supply module supplies the reagent to the reaction cell, and the control module performs the detection of the first protein-specific detection item on the sample through the reaction cell.

3. The sample analyzer of claim 1, wherein each of the specific protein detection modules includes a reaction cell and a detection cell, the sample module distributes the sample to the reaction cell, and the reagent supply module supplies the reagent to the reaction cell to react the sample and the reagent in the reaction cell; and the control module detects a first specific protein detection item on the reacted sample through the detection pool.

4. The sample analyzer of any of claims 1-3, further comprising a display module, the display module being coupled to the control module, the display module being configured to display the first test result.

5. The sample analyzer of any of claims 1-3, wherein the sample analyzer comprises four protein-specific detection modules for detecting the first protein-specific detection item and the second protein-specific detection item from the sample;

the control module is used for selecting two specific protein detection modules to calibrate the first specific protein detection item, calibrating the second specific protein detection item by the remaining two specific protein detection modules to obtain a first calibration curve and a second calibration curve, and storing the first calibration curve and the second calibration curve to the storage module.

6. The sample analyzer of any of claims 1-3, wherein the sample analyzer comprises four protein-specific detection modules for performing the first protein-specific detection item, the second protein-specific detection item, and the third protein-specific detection item on the sample;

the control module is configured to select two of the specific protein detection modules to calibrate the first specific protein detection item, sequentially calibrate the second specific protein detection item and the third specific protein detection item with the remaining two specific protein detection modules to obtain the first calibration curve, the second calibration curve and the third calibration curve, and store the first calibration curve, the second calibration curve and the third calibration curve in the storage module.

7. The sample analyzer of any of claims 1-3, wherein the sample analyzer comprises four specific protein detection modules for performing the first specific protein detection item, the second specific protein detection item, the third specific protein detection item, and the fourth specific protein detection item on the sample;

the control module is configured to select different specific protein detection modules from the four specific protein detection modules, to sequentially calibrate the first specific protein detection item, the second specific protein detection item, the third specific protein detection item, and the fourth specific protein detection item to obtain a first calibration curve, a second calibration curve, a third calibration curve, and a fourth calibration curve, and to store the first calibration curve, the second calibration curve, the third calibration curve, and the fourth calibration curve in the storage module.

8. The sample analyzer of any of claims 1-3, wherein the sample analyzer comprises four specific protein detection modules for performing the first specific protein detection item, the second specific protein detection item, the third specific protein detection item, the fourth specific protein detection item, the fifth specific protein detection item, and the sixth specific protein detection item on the sample;

the control module is configured to sequentially perform calibration on the first specific protein detection item, the second specific protein detection item, the third specific protein detection item, the fourth specific protein detection item, the fifth specific protein detection item, and the sixth specific protein detection item to obtain a first calibration curve, a second calibration curve, a third calibration curve, a fourth calibration curve, a fifth calibration curve, and a sixth calibration curve, and store the first calibration curve, the second calibration curve, the third calibration curve, the fourth calibration curve, the fifth calibration curve, and the sixth calibration curve in the storage module.

9. A sample analyzer, comprising:

a sample module for collecting and distributing samples;

a reagent supply module for supplying a reagent;

a blood routine detection module for performing blood routine detection on the sample;

10. A detection method of a sample analyzer, applied to the sample analyzer of claims 1-8 or 9, the detection method comprising:

storing a plurality of calibration curves to the storage module;

when the specific protein detection module detects a first specific protein detection item on the sample, a first calibration curve corresponding to the first specific protein detection item is obtained from the calibration curves, and a first detection result is obtained based on the first calibration curve.

11. The assay of claim 10, wherein the plurality of specific protein assay items includes the first specific protein assay item and a second specific protein assay item, and wherein prior to the step of obtaining the first calibration curve corresponding to the first specific protein assay item from the plurality of calibration curves, the assay further comprises:

controlling the specific protein detection module to switch from the second specific protein detection item to the first specific protein detection item;

judging whether the storage module comprises a first calibration curve corresponding to the first specific protein detection item;

if not, the first specific protein detection item is calibrated to obtain the first calibration curve, and the first calibration curve is stored in the storage module.

12. The inspection method of claim 10, wherein prior to the step of storing a plurality of calibration curves in the storage module, the inspection method further comprises:

and calibrating all specific protein detection items of each specific protein detection module to obtain a plurality of calibration curves, and storing the plurality of calibration curves into the storage module.

13. The assay of claim 10, wherein the sample analyzer comprises a plurality of protein-specific assay modules, and wherein prior to the step of storing the plurality of calibration curves in the storage module, the assay further comprises:

measuring each specific protein detection module for multiple times by using a plurality of standard samples with preset concentration values respectively to obtain a measurement result;

obtaining the calibration curve by using the measurement result, and storing the calibration curve to the storage module;

selecting a corresponding specific protein detection module according to the detection mode selected by the sample analyzer.

14. The assay of claim 10, wherein the sample analyzer comprises a plurality of specific protein assay modules, and prior to the step of storing the plurality of calibration curves in the storage module, the assay further comprises:

measuring a single specific protein detection module for multiple times by using standard samples with multiple preset concentration values corresponding to different specific protein detection items respectively to obtain measurement results;

obtaining a plurality of calibration curves corresponding to the specific protein detection items by using the measurement result, and storing the calibration curves into the storage module;

15. The method as claimed in claim 11, wherein the step of scaling the first specific protein assay item to obtain the first scaling curve comprises:

testing a plurality of standard samples with preset concentration values through the specific protein detection module to obtain measured values;

and obtaining the first calibration curve according to a regression curve between the preset concentration value and the measured value.

16. The inspection method of claim 10, wherein prior to said step of storing a plurality of calibration curves in said storage module, said inspection method further comprises:

when the sample analyzer swipes a reagent card, the plurality of calibration curves are imported from the reagent card so as to store the plurality of calibration curves in the storage module.