CN115779257B - Interventional catheter pump - Google Patents

Interventional catheter pump Download PDF

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Publication number
CN115779257B
CN115779257B CN202211450488.9A CN202211450488A CN115779257B CN 115779257 B CN115779257 B CN 115779257B CN 202211450488 A CN202211450488 A CN 202211450488A CN 115779257 B CN115779257 B CN 115779257B
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blood
pipe section
circular
pump
section
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CN115779257A (en
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陈增胜
李�远
樊瑜波
邓小燕
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Beihang University
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Beihang University
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Abstract

The invention discloses a novel interventional catheter pump, which relates to the field of medical instruments and comprises the following components: the sleeve comprises a first circular pipe section, a conical pipe section and a second circular pipe section which are sequentially communicated, the pipe diameter of the second circular pipe section is larger than that of the first circular pipe section, and a supporting shaft coaxial with the second circular pipe section is arranged in the second circular pipe section; a plurality of blood pumps, each blood pump being detachably connected to the support shaft; all blood pumps are connected in parallel and distributed along the circumferential direction of the support shaft, or all blood pumps are connected in series and distributed along the axial direction of the support shaft; all blood pumps are connected in parallel: a plurality of support rods are further arranged in the second circular tube section, the first ends of the support rods are connected with the inner wall of the second circular tube section, and the second ends of the support rods are connected with the support shafts; when all blood pumps are connected in series: one part of the supporting shaft is positioned in the second circular tube section, and the other part of the supporting shaft extends out of one end of the second circular tube section far away from the conical tube section. The invention can assist heart blood circulation and simultaneously reduce blood damage and vascular damage brought by the ventricular assist device.

Description

Interventional catheter pump
Technical Field
The invention relates to the field of medical instruments, in particular to an interventional catheter pump.
Background
Heart failure is an increasingly serious medical problem, with both morbidity and mortality. Ventricular Assist Devices (VADs) play an important role in the treatment of heart failure patients, and have been used clinically for many years and to rescue many patients. There is currently a microcatheter pump that is primarily used in the rescue of acute heart failure or in high risk PCI procedures, such as the Impella series. The catheter pump reaches the aortic arch mainly through femoral artery intervention and is inserted into the left ventricle through the aortic valve to assist or replace the heart pumping function, so that short-term support is provided for heart failure patients. Compared with the general VAD, the catheter pump has small volume, so that the catheter pump needs a very high rotating speed (30000 rpm or so) to meet the blood flow and pressure difference required by human body. This high rotational speed mode of operation causes such catheter pumps to generate, on the one hand, extremely large non-physiological shear forces, which can lead to more serious blood damage and complications such as thrombosis, hemolysis, bleeding, etc.; on the other hand, the high-speed blood flowing out of the catheter pump can impact the wall of the blood vessel, and damage the arterial blood vessel. These blood and vascular injuries and complications seriously affect the therapeutic effect of the VAD and the rehabilitation of the patient and may cause irreversible damage to the patient's body.
Disclosure of Invention
The invention aims to provide an interventional catheter pump, which solves the problems of the prior art and reduces the blood damage and the vascular damage caused by a ventricular assist device.
In order to achieve the above object, the present invention provides the following solutions:
the present invention provides an interventional catheter pump comprising:
the sleeve comprises a first circular pipe section, a conical pipe section and a second circular pipe section which are sequentially communicated, the pipe diameter of the second circular pipe section is larger than that of the first circular pipe section, and a supporting shaft coaxial with the second circular pipe section is arranged in the second circular pipe section;
a plurality of blood pumps, each of which is detachably connected with the support shaft;
all the blood pumps are connected in parallel and distributed along the circumferential direction of the supporting shaft, or all the blood pumps are connected in series and distributed along the axial direction of the supporting shaft;
all the blood pumps are connected in parallel: the second circular pipe section is also provided with a plurality of support rods, the first ends of the support rods are connected with the inner wall of the second circular pipe section, and the second ends of the support rods are connected with the support shafts;
when all the blood pumps are connected in series: one part of the supporting shaft is positioned in the second circular tube section, and the other part of the supporting shaft extends out of one end of the second circular tube section far away from the conical tube section.
Preferably, the blood pump comprises a liquid inlet pipe, a rotor, a blood pump diffuser and a motor; the pipe wall of the liquid inlet pipe is detachably connected with the supporting shaft; the rotor is arranged in the liquid inlet pipe; the blood pump diffuser is arranged at one end of the liquid inlet pipe far away from the cone pipe section, and all blood pump diffusers in the blood pump are positioned outside the second cone pipe section; the motor is used for driving the rotor to rotate, and is a waterproof motor; the rotor includes a rotor hub and rotor blades.
Preferably, the rotor hub is cone-shaped, and the tip of the rotor hub faces the cone pipe section; and the smaller end of the rotor hub is closer to the cone pipe section than the end of the rotor blade closer to the cone pipe section.
Preferably, the blood pump diffuser is curved in a direction opposite to the rotation direction of the rotor.
Preferably, all the blood pumps are uniformly distributed, and all the support rods are uniformly distributed along the circumferential direction of the support shaft; the second circular pipe section is a straight pipe.
Preferably, the end of the support shaft, which is close to the cone pipe section, is conical.
Preferably, an end of the first tubular segment remote from the conical tube segment is adapted to communicate with the left ventricle of the patient, the conical tube segment being placed in use in the aorta of the patient.
Preferably, a blood pump clip is arranged on the support shaft corresponding to each blood pump, and the blood pump clip is used for clamping the pipe wall of the liquid inlet pipe.
Preferably, the blood pump clamps and the support rods are distributed in a staggered manner.
Compared with the prior art, the invention has the following technical effects:
the rotational speed of each blood pump in the interventional catheter pump is low, and the blood damage and the blood vessel damage caused by the ventricular assist device can be reduced.
The multiple blood pumps in the interventional catheter pump are connected in series or in parallel, and the multiple blood pumps are operated simultaneously, so that the rotating speed of each blood pump can be greatly reduced compared with the existing VAD adopting only a single blood pump under the condition of ensuring that the output flow and the pressure difference of the VAD are unchanged, thereby reducing the high shear force output by the blood pump, reducing the damage of the operation of the blood pump to blood, improving the blood compatibility after the VAD is implanted and reducing complications.
Because a plurality of blood pumps run simultaneously, even if one blood pump fails or is damaged, other blood pumps can still provide life support for patients, and the risk brought by equipment failure is reduced.
The multiple blood pumps run simultaneously, and the rotating speed of the single pump is reduced under the condition of ensuring the same flow, so that the power requirement on the single blood pump is reduced, and each blood pump can be further reduced in size, so that the size of the whole blood pump is reduced, the blood pumps are convenient to install and place, and the rapid intervention of each blood pump is facilitated.
When multiple blood pumps of the present invention are connected in series, it is also possible to orient and provide support for other organs. For example, heart failure occurs, often accompanied by renal failure even with VAD assistance, the root cause of which is a double kidney insufficiency of blood supply; one of the blood pumps can be arranged near the kidney when the blood pumps are connected in series, so that the blood supply of the kidney is ensured while the heart failure patient is effectively helped, and the complications are further reduced; secondly, the radial dimension of the second circular tube segment 114 can be effectively reduced by connecting a plurality of blood pumps in series, so that a support rod is not needed, the cost is low, the dimension of a wound during implantation can be further reduced, and the wound caused by implantation is reduced.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions of the prior art, the drawings that are needed in the embodiments will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic illustration of a first embodiment of an interventional catheter pump of the present invention;
FIG. 2 is a schematic view of a portion of a first embodiment of an interventional catheter pump of the present invention;
FIG. 3 is a schematic view of a portion of a first embodiment of an interventional catheter pump of the present invention;
FIG. 4 is a schematic view of a portion of a first embodiment of an interventional catheter pump of the present invention;
FIG. 5 is a schematic view of a portion of a first embodiment of an interventional catheter pump of the present invention;
FIG. 6 is a schematic view of a portion of a first embodiment of an interventional catheter pump of the present invention;
FIG. 7 is a schematic view of a portion of a first embodiment of an interventional catheter pump of the present invention;
FIG. 8 is a schematic view of a portion of a first embodiment of an interventional catheter pump of the present invention;
FIG. 9 is a schematic diagram of a second embodiment of an interventional catheter pump of the present invention;
FIG. 10 is a schematic view of a portion of a second embodiment of an interventional catheter pump of the present invention;
FIG. 11 is a schematic view of a portion of a second embodiment of an interventional catheter pump of the present invention;
wherein, 1, the sleeve pipe; 111. a sleeve inlet; 112. a first circular tube section; 113. a cone pipe section; 114. a second circular tube section; 12. a support shaft; 13. a support rod; 14. a blood pump clip; 15. a sleeve support line; 2. a blood pump; 21. a liquid inlet pipe; 22. a rotor; 221. a rotor blade; 222. a rotor hub; 23. a blood pump diffuser; 24. a motor; 25. and (5) conducting wires.
Description of the embodiments
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The invention aims to provide an interventional catheter pump, which solves the problems of the prior art and reduces the blood damage and the vascular damage caused by a ventricular assist device.
In order that the above-recited objects, features and advantages of the present invention will become more readily apparent, a more particular description of the invention will be rendered by reference to the appended drawings and appended detailed description.
Examples
As shown in fig. 1-8, the present embodiment provides an interventional catheter pump, which includes a cannula 1 and a plurality of blood pumps 2, and in this embodiment, the number of the blood pumps 2 is four, and in practical application, the number of the blood pumps 2 can be adaptively adjusted according to actual needs.
Wherein, the sleeve 1 comprises a first circular tube section 112, a taper tube section 113 and a second circular tube section 114 which are sequentially communicated, the diameter of the second circular tube section 114 is larger than that of the first circular tube section 112, so as to facilitate the installation of a plurality of blood pumps 2 in the second circular tube section 114, and a support shaft 12 coaxial with the second circular tube section 114 is arranged in the second circular tube section 114; the end of the supporting shaft 12, which is close to the cone pipe section 113, is conical, so that the supporting shaft 12 plays a certain role in guiding flow, and the damage to blood caused by the direct collision of blood with the supporting shaft 12 of the sleeve 1 can be avoided; the end of the support shaft 12 remote from the cone tube section 113 is also connected to a cannula support wire 15, the cannula support wire 15 being used for assisting in the delivery and removal of the interventional catheter pump of the present embodiment into and from the human blood vessel.
The end of the first circular tube segment 112 remote from the conical tube segment 113 (i.e., the inlet of the cannula 1) is adapted to communicate with the left ventricle of the patient, with a portion of the first circular tube segment 112 passing through the aorta and another portion of the first circular tube segment 112, the conical tube segment 113 and the second circular tube segment 114 being disposed in use in the aortic arch of the patient.
The first circular tube segment 112 has a tube diameter ranging between 3mm and 15mm to facilitate insertion of the first circular tube segment 112 from the aortic valve into the left ventricle. The first circular tube segment 112 is configured to curve to better conform to the shape of the aortic arch. The second circular tube segment 114 is a straight tube, and the materials of the first circular tube segment, the second circular tube segment 114 and the taper tube segment 113 are the same as those used in the conventional VAD catheter.
In this embodiment, a plurality of support rods 13 are further disposed in the second circular tube segment 114, a first end of each support rod 13 is connected to the inner wall of the second circular tube segment 114, and a second end of each support rod 13 is connected to the support shaft 12; all the support rods 13 are uniformly distributed along the circumferential direction of the support shaft 12.
The blood pump 2 is an axial flow pump. Specifically, the blood pump 2 includes a liquid inlet tube 21, a rotor 22, a blood pump diffuser 23, and a motor 24; the pipe wall of the liquid inlet pipe 21 is detachably connected with the supporting shaft 12; the rotor 22 is arranged in the liquid inlet pipe 21; the blood pump diffuser 23 is arranged at one end of the liquid inlet pipe 21 far away from the cone pipe section 113, and the blood pump diffusers 23 in all the blood pumps 2 are positioned outside the second circular pipe section 114 so as to avoid the obstruction of the second circular pipe section 114 on the blood flowing out of the diffuser and the blood damage caused by the collision of the part of the blood with the second circular pipe section 114; the motor 24 is used for driving the rotor 22 to rotate, and the motor 24 is a waterproof motor 24; rotor 22 includes a rotor hub 222 and rotor blades 221.
Rotor hub 222 is tapered, with the smaller end of rotor hub 222 being closer to cone segment 113 than the other end (i.e., the tip of rotor hub 222 is oriented toward cone segment 113); and the smaller end of rotor hub 222 is closer to cone segment 113 than the end of rotor blade 221 near cone segment 113, thereby make the smaller end of rotor hub 222 play the effect of water conservancy diversion, and make the smaller end of rotor hub 222 be closer to cone segment 113 than the end of rotor blade 221 near cone segment 113 can increase the conveying effect of blood pump 2 under the unchangeable condition of rotor blade 221 length, thereby reduce blood pump 2 rotational speed, the bigger end of rotor hub 222 is farther away from cone segment 113 than the end of rotor blade 221 far away from cone segment 113.
Rotor blades 221 are banana-shaped blades, with a recommended number of 1-4. The banana-shaped rotor blades 221 can normalize blood flow in the blood pump 2, reducing blood damage caused by flow separation.
The direction of curvature of the blood pump diffuser 23 is opposite to the direction of rotation of the rotor 22 to enhance the pressurization of the blood pump diffuser 23 and reduce the effect of pre-rotation in the blood after acceleration by the rotor blades 221 on subsequent arterial blood flow. At the same time, the blood pump diffuser 23 also serves to connect the inlet tube 21 with the motor 24.
In the present embodiment, all the blood pumps 2 are connected in parallel and uniformly distributed along the circumferential direction of the support shaft 12, and each blood pump 2 is detachably connected with the support shaft 12; specifically, the supporting shaft 12 is provided with a blood pump clip 14 corresponding to each blood pump 2, and the blood pump clip 14 can be used for clamping the tube wall of the liquid inlet tube 21, so that the stability of the blood pump 2 in the space position is ensured. All the blood pump clamps 14 are uniformly distributed along the circumferential direction of the support shaft 12, and the blood pump clamps 14 and the support rods 13 are distributed in a staggered manner so as to avoid the interference of the support rods 13 on the flow field of the blood pump 2.
The lead 25 of the motor 24 of the blood pump 2 extends out of the sleeve 1 and is electrically connected with a control device, and the opening and closing and the rotating speed of each blood pump 2 can be controlled by the control device; the total output flow and the total pressure difference meet the requirements by adjusting the rotation speed of each blood pump 2; the related arrangement of the control device and the power supply of the motor 24 is a prior art, and will not be described in detail in this embodiment.
The specific working process of the interventional catheter pump of the embodiment is as follows:
under the suction action of the blood pump 2, firstly, blood enters from the sleeve inlet 111 (i.e. the end of the first circular tube section 112 far away from the conical tube section 113) and passes through the first circular tube section 112 and the conical tube section 113 to reach the sleeve 1 support shaft 12; the top of the sleeve 1 supporting shaft 12 is conical, has a certain diversion effect, and can also avoid blood damage caused by direct impact of blood with the sleeve 1 supporting shaft 12. The blood then enters the inlet tube 21 to the rotor 22 basin. Under the action of the rotor 22, the blood gains velocity energy. Finally, the blood enters the blood pump diffuser 23, and the velocity energy is converted into pressure energy and then flows out. The outlet of the cannula 1 should be in front of the blood pump diffuser 23 to avoid obstruction of the blood flowing out of the diffuser by the cannula 1 housing and damage to the blood caused by this blood impinging on the cannula 1 housing. The demand can be satisfied by adjusting the rotational speed of each blood pump 2 by making the total output flow rate and the total pressure difference thereof.
Examples
As shown in fig. 9 to 11, the present embodiment provides an interventional catheter pump, which is basically identical in structure and operation principle to the interventional catheter pump of the first embodiment, except that:
in the present embodiment, all blood pumps 2 are connected in series and distributed along the axial direction of the support shaft 12. The second circular tube segment 114 is not provided with the supporting rod 13, and the supporting shaft 12 is fixedly connected with the second circular tube segment 114, or may be designed as a whole, so that the supporting shaft 12 and the second circular tube segment 114 are integrally formed. While, since the blood pump 2 is distributed along the axial direction of the support shaft 12, the blood pump clamps 14 are also distributed along the axial direction of the support shaft 12. The support shaft 12 is partially disposed in the second circular tube segment 114 and partially extends beyond the end of the second circular tube segment 114 remote from the tapered tube segment 113.
In this embodiment, the blood pump diffuser 23 of all the blood pumps 2 is also located outside the second circular tube segment 114, so as to avoid the obstruction of the second circular tube segment 114 to the blood flowing out of the diffuser and the damage of the blood caused by the collision of the blood with the second circular tube segment 114.
In this embodiment, the plurality of blood pumps 2 are connected in series, so that the radial dimension of the second circular tube segment 114 can be effectively reduced, the support rod 13 is not needed, the cost is low, and the implantation wound can be further reduced.
The principles and embodiments of the present invention have been described in detail with reference to specific examples, which are provided to facilitate understanding of the method and core ideas of the present invention; also, it is within the scope of the present invention to be modified by those of ordinary skill in the art in light of the present teachings. In view of the foregoing, this description should not be construed as limiting the invention.

Claims (5)

1. An interventional catheter pump, comprising:
the sleeve comprises a first circular pipe section, a conical pipe section and a second circular pipe section which are sequentially communicated, the pipe diameter of the second circular pipe section is larger than that of the first circular pipe section, and a supporting shaft coaxial with the second circular pipe section is arranged in the second circular pipe section;
a plurality of blood pumps, each of which is detachably connected with the support shaft;
all the blood pumps are connected in parallel and distributed along the circumferential direction of the supporting shaft, or all the blood pumps are connected in series and distributed along the axial direction of the supporting shaft;
all the blood pumps are connected in parallel: the second circular pipe section is also provided with a plurality of support rods, the first ends of the support rods are connected with the inner wall of the second circular pipe section, and the second ends of the support rods are connected with the support shafts;
when all the blood pumps are connected in series: one part of the supporting shaft is positioned in the second circular tube section, and the other part of the supporting shaft extends out of one end of the second circular tube section far away from the conical tube section;
the blood pump comprises a liquid inlet pipe, a rotor, a blood pump diffuser and a motor; the pipe wall of the liquid inlet pipe is detachably connected with the supporting shaft; the rotor is arranged in the liquid inlet pipe; the blood pump diffuser is arranged at one end of the liquid inlet pipe far away from the cone pipe section, and all blood pump diffusers in the blood pump are positioned outside the second cone pipe section; the motor is used for driving the rotor to rotate, and is a waterproof motor; the rotor includes a rotor hub and rotor blades; the rotor hub is conical, and the tip end of the rotor hub faces the taper pipe section; and the smaller end of the rotor hub is closer to the cone pipe section than the end of the rotor blade, which is closer to the cone pipe section;
a blood pump clamp is arranged on the support shaft corresponding to each blood pump, and the blood pump clamps are used for clamping the pipe wall of the liquid inlet pipe; the blood pump clamps and the support rods are distributed in a staggered mode.
2. The interventional catheter pump of claim 1, wherein: the blood pump diffuser is curved in a direction opposite to the direction of rotation of the rotor.
3. The interventional catheter pump of claim 1, wherein: all the blood pumps are uniformly distributed, and all the support rods are uniformly distributed along the circumferential direction of the support shaft; the second circular pipe section is a straight pipe.
4. The interventional catheter pump of claim 1, wherein: the support shaft is close to one end of the cone pipe section and is conical.
5. The interventional catheter pump of claim 1, wherein: one end of the first circular tube section, which is far away from the conical tube section, is used for being communicated with the left ventricle of the patient, and the conical tube section is placed in the aorta of the patient when in use.
CN202211450488.9A 2022-11-15 2022-11-15 Interventional catheter pump Active CN115779257B (en)

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CN115779257B true CN115779257B (en) 2023-07-18

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0847767A1 (en) * 1996-12-13 1998-06-17 Micromed Technology, Inc. Rotary blood pump
CN108136088A (en) * 2015-10-12 2018-06-08 柏林心脏有限公司 There are two the heart assist systems pumped for tool
CN113663211A (en) * 2015-08-04 2021-11-19 阿比奥梅德欧洲股份有限公司 Blood pump
CN114177516A (en) * 2021-12-22 2022-03-15 江苏大学 High-flow two-stage catheter pump for left ventricle assistance and using method thereof
CN114602055A (en) * 2022-03-07 2022-06-10 江苏大学镇江流体工程装备技术研究院 Multistage catheter blood pump for emergency type rapid minimally invasive implantation
CN115066269A (en) * 2020-02-06 2022-09-16 阿比奥梅德欧洲股份有限公司 Blood pump placement and intravascular blood pump

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101361994B (en) * 2008-09-12 2010-11-10 北京工业大学 Artificial heart blood-pump capable of increasing blood pressure step by step
CN113648535A (en) * 2021-08-11 2021-11-16 河南科技大学 Nested multistage parallel blood pump capable of realizing large-flow pulsation output
CN219148993U (en) * 2022-07-19 2023-06-09 安徽通灵仿生科技有限公司 Interventional type heart and kidney combined auxiliary assembly

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0847767A1 (en) * 1996-12-13 1998-06-17 Micromed Technology, Inc. Rotary blood pump
CN113663211A (en) * 2015-08-04 2021-11-19 阿比奥梅德欧洲股份有限公司 Blood pump
CN108136088A (en) * 2015-10-12 2018-06-08 柏林心脏有限公司 There are two the heart assist systems pumped for tool
CN115066269A (en) * 2020-02-06 2022-09-16 阿比奥梅德欧洲股份有限公司 Blood pump placement and intravascular blood pump
CN114177516A (en) * 2021-12-22 2022-03-15 江苏大学 High-flow two-stage catheter pump for left ventricle assistance and using method thereof
CN114602055A (en) * 2022-03-07 2022-06-10 江苏大学镇江流体工程装备技术研究院 Multistage catheter blood pump for emergency type rapid minimally invasive implantation

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