CN115747036B - Method for searching and screening laser wavelength capable of being strongly absorbed by flora - Google Patents
Method for searching and screening laser wavelength capable of being strongly absorbed by flora Download PDFInfo
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- CN115747036B CN115747036B CN202310014798.4A CN202310014798A CN115747036B CN 115747036 B CN115747036 B CN 115747036B CN 202310014798 A CN202310014798 A CN 202310014798A CN 115747036 B CN115747036 B CN 115747036B
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Abstract
The invention discloses a device and a method for searching and screening laser wavelength capable of being strongly absorbed by flora. The device comprises an optical cavity, wherein two ends of the optical cavity are provided with openings; the photoelectric detectors are arranged at two ends of the optical cavity and block openings at two ends of the optical cavity; the culture dish is clamped in the optical cavity and is parallel to the photoelectric detector for placing culture solution and flora; the optical fiber is arranged on the photoelectric detector opposite to the front surface of the culture dish in a penetrating way and is used for being connected with an adjustable light source. The device can effectively find the laser wavelength strongly absorbed by the flora by a method of 'relative absorption intensity measurement-wavelength selection-test confirmation'; and the culture dish can be taken out from the optical cavity, so that the flora can be placed on the culture dish or removed, and further two test results of the flora and the aseptic flora can be obtained, so that interference factors can be eliminated, and the accuracy of the test results can be improved. In addition, the adjustable light source covers the ultraviolet to infrared wave band, so that the comprehensiveness of the test can be improved.
Description
Technical Field
The invention relates to a method for searching and screening laser wavelength capable of being strongly absorbed by flora, belonging to the technical field of analysis and test.
Background
Trichophyton rubrum can cause onychomycosis to appear in human body, and influence human health. The trichophyton rubrum contains melanin in the cell body, can absorb laser light with a specific wavelength, and can inhibit the trichophyton rubrum in the tinea manus and pedis by irradiation of near infrared laser light. However, if it is desired to suppress and sterilize trichophyton rubrum, it is necessary to determine the wavelength range of the laser light to ensure a strong absorption effect of the laser light by the flora. Therefore, there is a need for a device or method for testing strong absorption wavelengths of bacterial groups to solve the above technical problems.
In the chinese patent application with application number 201610079372.7, a method for rapidly classifying bacterial colonies on a culture medium is disclosed, a hyperspectral imaging system is used for collecting a reflection image of each bacterial colony on the culture medium, the image contains spectral information and image information of each bacterial colony, a correction image is obtained after correction of a hyperspectral reflection image by a black-white file, a mask image of an original hyperspectral image is obtained by processing the correction image by an image processing technology, spectral data information of each bacterial colony is extracted by using a position of each bacterial colony in the mask image, and a full-wavelength linear prediction model based on bacterial category and spectral data information is established.
In addition, in the chinese patent application No. 201510551898.6, a method for identifying bacteria in water using transmission spectroscopy is disclosed. The method comprises the steps of performing 24-hour pure-breeding activation culture on bacteria to be identified in a laboratory, measuring and obtaining ultraviolet-visible multi-wavelength transmission spectrum of pathogenic bacteria, taking the ultraviolet-visible multi-wavelength transmission spectrum as a training set, and establishing a bacteria rapid classification identification model. The transmission spectra of the same bacteria cultured in different batches are measured as a test set and brought into a model to realize the identification of the bacterial species.
Disclosure of Invention
The invention aims to provide a method for searching and screening laser wavelength which can be strongly absorbed by flora.
In order to achieve the technical purpose, the invention adopts the following technical scheme:
a method of finding and screening laser wavelengths that are strongly absorbed by a population of bacteria, comprising the steps of:
s1: acquiring the absorption intensity of the flora on different wavelengths by using a preset device so as to select a strong absorption spectrum of the flora; wherein the device comprises:
the optical cavity is provided with openings at two ends, and the inner wall of the optical cavity is coated or stuck with a reflecting material to form an inner wall reflecting layer;
the two photoelectric detectors are respectively arranged at two ends of the optical cavity and block openings at two ends of the optical cavity;
the culture dish is clamped in the optical cavity and is parallel to the photoelectric detector so as to be used for placing culture solution and flora;
the optical fiber is arranged on the photoelectric detector opposite to the front surface of the culture dish in a penetrating way and is connected with the adjustable light source; the adjustable light source is a test light source which covers the wave band from ultraviolet to infrared and has tunable wavelength;
s2: selecting a plurality of matched laser light sources based on the strong absorption spectrum of the flora;
s3: and sequentially carrying out irradiation test and observation on the bacterial groups one by utilizing the plurality of laser light sources so as to obtain an irradiation test result, thereby confirming the strong absorption wavelength and the action parameters for inhibiting the growth of the bacterial groups.
Preferably, the step S1 specifically includes:
s11: acquiring a first test result of the device under the irradiation of laser with a first wavelength in a state that a culture solution and a flora are placed in the culture dish;
s12: acquiring a second test result of the device under the irradiation of the laser with the first wavelength in a state of removing the flora in the culture dish;
s13: calculating the absorption intensity of the flora to the laser of the first wavelength based on the first test result and the second test result;
s14: repeating the steps S11 to S13 to obtain the absorption intensity of the flora on the lasers with different wavelengths;
s15: and selecting a strong absorption spectrum of the flora according to the absorption intensity of the flora on the lasers with different wavelengths.
Preferably, the step S11 specifically includes:
s111: irradiating a culture dish with a culture solution and a flora with laser light of a first wavelength, wherein the incident light power of the laser light of the first wavelength is P 0 ；
S112: the emergent light power P is collected by the photoelectric detector 1 Wherein the emergent light power P 1 For reflecting power P Reverse-rotation Transmitted power P Penetrating pipe Scattered power P Powder medicine And (3) summing;
s113: will incident light power P 0 And the emergent light power P 1 As the first test result Δp, where Δp=p 0 －P 1 。
Preferably, the step S12 specifically includes:
s121: irradiating the culture dish with laser of first wavelength to remove floraWherein the incident light power of the laser with the first wavelength is P 0 ；
S122: the emergent light power P is collected by the photoelectric detector 1 ' wherein the outgoing light power P 1 ' is the reflected power P Reverse-rotation ' transmitted power P Penetrating pipe ' and scattered power P Powder medicine Sum of';
s123: will incident light power P 0 And the emergent light power P 1 The ' difference is taken as the second test result Δp ', where Δp ' =p 0 －P 1 ’。
Preferably, the step S13 specifically includes:
taking the difference percentage D of the absorption power of the two tests as the absorption intensity of the flora on the laser with the first wavelength; wherein d= (Δp- Δp')/P 0 。
Wherein preferably, the step S2 specifically comprises
Determining a plurality of absorption intensity points in the strong absorption spectrum;
and selecting a laser light source which is matched with the wavelength threshold value within the wavelength threshold value by taking the wavelength of each absorption strong point as the center and taking the preset range as the wavelength threshold value.
Preferably, the step S3 specifically includes:
irradiating the flora by a laser light source through a spectrum measuring device;
collecting irradiation data of the laser light source on the flora;
performing data processing on the irradiation data to obtain an inhibition growth index of the laser light source on the flora;
repeating the steps to obtain the growth inhibition indexes of different laser light sources on the flora;
and according to the growth inhibition indexes of the different laser light sources on the bacterial flora, the wavelength corresponding to the laser light source with the optimal growth inhibition function is taken as the strong absorption wavelength for inhibiting the bacterial flora growth.
Compared with the prior art, the invention has the following technical effects:
1. the laser wavelength strongly absorbed by the bacterial colony can be effectively searched by the method of 'relative absorption intensity measurement-wavelength selection-test confirmation'.
2. The culture dish can be taken out from the optical cavity, so that the flora can be placed on the culture dish or removed, and further two test results with the flora and the aseptic flora can be obtained, interference factors can be eliminated, and the accuracy of the test results is improved.
3. The tunable light source can cover the wave band from ultraviolet to infrared and has tunable wavelength, thereby improving the comprehensiveness of the test.
4. The photoelectric detector is conformal with the optical cavity, so that sealing can be realized to avoid the influence of laser exposure on detection precision.
Drawings
FIG. 1 is a schematic diagram of a device for searching and screening laser wavelength strongly absorbable by a bacterial colony according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of a device for searching and screening laser wavelengths strongly absorbable by a group of bacteria in a sterile state according to an embodiment of the present invention;
FIG. 3 is a flow chart of a method for finding and screening laser wavelengths that can be strongly absorbed by a population of bacteria according to an embodiment of the present invention.
Detailed Description
The technical contents of the present invention will be described in detail with reference to the accompanying drawings and specific examples.
As shown in fig. 1, an embodiment of the present invention firstly provides a device for searching and screening laser wavelengths which can be strongly absorbed by flora, and the device at least comprises an optical cavity 1, a photoelectric detector 2, a culture dish 3 and an optical fiber 4. Wherein the optical cavity 1 is used for performing optical testing; the photoelectric detectors 2 are blocked at two ends of the optical cavity 1 and are used for detecting emergent light power; a culture dish 3 is positioned in the optical cavity 1 for placing the culture solution 301 and the flora 302; an optical fiber 4 is provided to penetrate one of the photodetectors 2 for laser irradiation toward the culture dish 3.
Specifically, in one embodiment of the present invention, the optical cavity 1 is cylindrical and has openings at both ends. The inner wall of the optical cavity 1 is coated or stuck with a reflective material, so as to form an inner wall reflective layer 11, so as to improve the reflective effect of the incident laser in the optical cavity 1, and further improve the power detection accuracy of the photoelectric detector 2. It will be appreciated that in other embodiments, the shape of the optical cavity 1, as well as the specific materials of the reflective material, may be adaptively selected as desired.
As shown in fig. 1, in the embodiment of the present invention, two photodetectors 2 are provided, and both photodetectors 2 are circular, so that the two photodetectors can be sealed at the openings at two ends of the optical cavity 1 to detect the power of the outgoing light. In addition, the photoelectric detector 2 is conformal with the optical cavity 1, so that sealing can be realized to avoid the influence of laser exposure on detection precision. It will be appreciated that the specific sealing means may be adapted as desired, for example: in one embodiment of the invention, the diameter of the photodetector 2 may be slightly larger than the inner diameter of the optical cavity 1, thereby enabling an interference fit of the photodetector 2 with the optical cavity 1 to achieve a seal. In another embodiment, the diameter of the photodetector 2 may be slightly smaller than the inner diameter of the optical cavity 1, and a sealing ring is sleeved outside the photodetector 2 to realize sealing.
The culture dish 3 takes the shape of a disc, and the culture dish 3 is clamped in the optical cavity 1 and is parallel to the photoelectric detector 2. Specifically, a limiting step (not shown in the drawing) is formed on the inner wall of the optical cavity 1, on which the culture dish 3 is placed for placing the culture liquid 301 and the flora 302. It will be appreciated that, referring to fig. 1 and 2, in one embodiment of the present invention, the culture dish 3 may be removed from the optical cavity 1, so that the flora 302 may be placed on the culture dish 3 or the flora 302 may be removed, so that two test results with flora and asepsis may be obtained, for eliminating interference factors, and improving accuracy of the test results.
An optical fiber 4 is provided through one of the photodetectors 2 for connection to an adjustable light source (not shown). It will be appreciated that the photodetector 2 through which the optical fibre 4 is threaded should be opposed to the front face of the dish 3 so that laser light from the adjustable light source can be directed through the optical fibre 4 to the front face of the dish 3. The adjustable light source is a test light source which covers the wave band from ultraviolet to infrared and has tunable wavelength, so that the comprehensiveness of the test is improved.
As shown in fig. 3, the embodiment of the present invention further provides a method for searching and screening laser wavelengths that can be strongly absorbed by a flora, which is implemented based on the above device, and specifically includes steps S1 to S3:
s1: the absorption intensities of the bacterial flora 302 at different wavelengths are obtained to select a strong absorption spectrum of the bacterial flora 302.
Specifically, the method comprises the steps S11 to S15:
s11: in a state where the culture solution 301 and the bacterial group 302 are placed in the culture dish 3, a first test result of the apparatus under the irradiation of the laser light of the first wavelength is obtained.
Specifically, first, a first wavelength of laser light having an incident light power of P is irradiated onto a culture dish 3 on which a culture solution 301 and a bacterial group 302 are placed 0 . Then, the outgoing light power P is collected by the photodetector 2 1 Wherein the emergent light power P 1 For reflecting power P Reverse-rotation Transmitted power P Penetrating pipe Scattered power P Powder medicine The sum is that: p (P) 1 ＝P Reverse-rotation +P Penetrating pipe +P Powder medicine . Finally, the incident light power P 0 And the emergent light power P 1 As a first test result Δp, where Δp=p 0 －P 1 。
S12: in a state in which the flora is removed from the culture dish, a second test result of the device under the irradiation of the laser with the first wavelength is obtained.
Specifically, first, a first wavelength of laser light is irradiated on a culture dish 3 from which a flora is removed, wherein the incident light power of the first wavelength of laser light is P 0 . Then, the outgoing light power P is collected by the photodetector 2 1 ' wherein the emitted light power P 1 ' is the reflected power P Reverse-rotation ' transmitted power P Penetrating pipe ' and scattered power P Powder medicine The sum of': p (P) 1 ’＝P Reverse-rotation ’+P Penetrating pipe ’+P Powder medicine '. Finally, the incident light power P 0 And the emergent light power P 1 The ' difference is taken as a second test result Δp ', where Δp ' =p 0 －P 1 ’。
S13: and calculating the absorption intensity of the flora to the laser with the first wavelength based on the first test result and the second test result.
Specifically, in one embodiment of the present invention, the percentage difference in absorption power between two tests, D, is taken as the absorption intensity of the first wavelength laser by the flora; wherein d= (Δp- Δp')/P 0 。
S14: the steps S11 to S13 are repeated to obtain the absorption intensities of the laser beams with different wavelengths by the bacterial group 302.
S15: the strong absorption spectrum of the bacterial flora 302 is selected according to the absorption intensity of the bacterial flora 302 to the laser light with different wavelengths.
S2: based on the strong absorption spectrum of the flora, a plurality of matched laser light sources are selected.
Specifically, in one embodiment of the present invention, first, a plurality of absorption intensity points are determined in a strong absorption spectrum; then, a laser light source adapted within a wavelength threshold is selected with respect to the wavelength of each absorption intensity point as a center and a preset range as a wavelength threshold. Thus, a plurality of laser sources can be matched in the common laser sources.
S3: and sequentially carrying out irradiation test and observation on the bacterial groups one by utilizing a plurality of laser light sources to obtain an irradiation test result, thereby confirming the strong absorption wavelength and the action parameters for inhibiting the growth of the bacterial groups.
Specifically, the method comprises the steps S31 to S35:
s31: irradiating the flora 302 with a laser light source by a spectrometry device; the spectrum measuring device is used for testing the laser light source;
s32: collecting irradiation data of a laser light source on the flora 302;
s33: performing data processing on the irradiation data to obtain an inhibition growth index of the laser light source on the flora 302;
s34: repeating the steps S31-S33 to obtain the inhibition growth indexes of different laser light sources on the flora 302;
s35: according to the growth inhibition index of different laser light sources to the flora 302, the wavelength corresponding to the laser light source with the optimal growth inhibition function is taken as the strong absorption wavelength for inhibiting the growth of the flora.
Thus, the strong absorption wavelength of the bacterial flora can be tested by the device for the strong absorption wavelength through the steps S1 to S3, so that the strong absorption wavelength for inhibiting the growth of the bacterial flora can be determined.
In summary, the device and the method for searching and screening the laser wavelength capable of being strongly absorbed by the flora provided by the embodiment of the invention have the following beneficial effects:
1. the method of "measurement of relative absorption intensity (corresponding to step S1) -selection of wavelength (corresponding to step S2) -test confirmation (corresponding to step S3)" allows efficient search of the laser wavelength strongly absorbed by the bacterial group.
2. The culture dish 3 can be taken out from the optical cavity 1, so that the flora 302 can be placed on the culture dish 3 or the flora 302 can be removed, and further two test results with the flora and the aseptic flora can be obtained, so that interference factors can be eliminated, and the accuracy of the test results can be improved.
3. The tunable light source can cover the wave band from ultraviolet to infrared and has tunable wavelength, thereby improving the comprehensiveness of the test.
4. The photoelectric detector 2 is conformal with the optical cavity 1, so that sealing can be realized to avoid the influence of laser exposure on detection precision.
The method for searching and screening the laser wavelength which can be strongly absorbed by the flora provided by the invention is described in detail above. Any obvious modifications to the present invention, without departing from the spirit thereof, would constitute an infringement of the patent rights of the invention and would take on corresponding legal liabilities.
Claims (7)
1. A method for finding and screening laser wavelengths that are strongly absorbed by a population of bacteria, comprising the steps of:
s1: acquiring the absorption intensity of the flora on different wavelengths by using a preset device so as to select a strong absorption spectrum of the flora; wherein the device comprises:
the optical cavity is provided with openings at two ends, and the inner wall of the optical cavity is coated or stuck with a reflecting material to form an inner wall reflecting layer;
the two photoelectric detectors are respectively arranged at two ends of the optical cavity and block openings at two ends of the optical cavity;
the culture dish is clamped in the optical cavity and is parallel to the photoelectric detector so as to be used for placing culture solution and flora;
the optical fiber is arranged on the photoelectric detector opposite to the front surface of the culture dish in a penetrating way and is connected with the adjustable light source; the adjustable light source is a test light source which covers the wave band from ultraviolet to infrared and has tunable wavelength;
s2: selecting a plurality of matched laser light sources based on the strong absorption spectrum of the flora;
s3: and sequentially carrying out irradiation test and observation on the bacterial groups one by utilizing the plurality of laser light sources so as to obtain an irradiation test result, thereby confirming the strong absorption wavelength and the action parameters for inhibiting the growth of the bacterial groups.
2. The method according to claim 1, wherein said step S1 comprises:
s11: acquiring a first test result of the device under the irradiation of laser with a first wavelength in a state that a culture solution and a flora are placed in the culture dish;
s12: acquiring a second test result of the device under the irradiation of the laser with the first wavelength in a state of removing the flora in the culture dish;
s13: calculating the absorption intensity of the flora to the laser of the first wavelength based on the first test result and the second test result;
s14: repeating the steps S11 to S13 to obtain the absorption intensity of the flora on the lasers with different wavelengths;
s15: and selecting a strong absorption spectrum of the flora according to the absorption intensity of the flora on the lasers with different wavelengths.
3. The method according to claim 2, characterized in that said step S11 comprises in particular:
s111: irradiating a culture dish with a culture solution and a flora with laser light of a first wavelength, wherein the incident light power of the laser light of the first wavelength is P 0 ；
S112: the emergent light power P is collected by the photoelectric detector 1 Wherein the emergent light power P 1 For reflecting power P Reverse-rotation Transmitted power P Penetrating pipe Scattered power P Powder medicine And (3) summing;
s113: will incident light power P 0 And the emergent light power P 1 As the first test result Δp, where Δp=p 0 －P 1 。
4. A method according to claim 3, characterized in that said step S12 comprises in particular:
s121: irradiating a culture dish with a first wavelength of laser with incident light power of P 0 ；
S122: the emergent light power P is collected by the photoelectric detector 1 ' wherein the outgoing light power P 1 ' is the reflected power P Reverse-rotation ' transmitted power P Penetrating pipe ' and scattered power P Powder medicine Sum of';
s123: will incident light power P 0 And the emergent light power P 1 The ' difference is taken as the second test result Δp ', where Δp ' =p 0 －P 1 ’。
5. The method according to claim 4, wherein the step S13 specifically includes:
the absorption power difference percentage D of the two tests is taken as the absorption intensity of the flora to the laser with the first wavelengthA degree; wherein d= (Δp- Δp')/P 0 。
6. The method according to claim 2, wherein said step S2 comprises
Determining a plurality of absorption intensity points in the strong absorption spectrum;
and selecting a laser light source which is matched with the wavelength threshold value within the wavelength threshold value by taking the wavelength of each absorption strong point as the center and taking the preset range as the wavelength threshold value.
7. The method according to claim 2, characterized in that said step S3 comprises in particular:
irradiating the flora by a laser light source through a spectrum measuring device;
collecting irradiation data of the laser light source on the flora;
performing data processing on the irradiation data to obtain an inhibition growth index of the laser light source on the flora;
repeating the steps to obtain the growth inhibition indexes of different laser light sources on the flora;
and according to the growth inhibition indexes of the different laser light sources on the bacterial flora, the wavelength corresponding to the laser light source with the optimal growth inhibition function is taken as the strong absorption wavelength for inhibiting the bacterial flora growth.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1800340A (en) * | 2004-12-31 | 2006-07-12 | 王衍淞 | Illumination method using when obtaining culture dish colony image |
| CN103616383A (en) * | 2013-12-02 | 2014-03-05 | 江苏大学 | Method for quantitatively detecting stability of flora structure in batch food fermentation process |
| CN105651679A (en) * | 2016-02-04 | 2016-06-08 | 华中农业大学 | Method for quickly classifying bacterial colonies on culture medium on basis of hyperspectral imaging technology |
| CN108918444A (en) * | 2018-07-23 | 2018-11-30 | 哈尔滨理工大学 | The detection method of Escherichia coli in cow's milk based on ultraviolet-visible light spectral technology |
| CN114839145A (en) * | 2022-05-07 | 2022-08-02 | 福建福晶科技股份有限公司 | Laser damage analysis test instrument |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2229980B1 (en) * | 2009-03-16 | 2015-08-12 | Nuvolase, Inc. | Treatment of microbiological pathogens in a toe nail with antimicrobial light |
| CN203117104U (en) * | 2012-12-11 | 2013-08-07 | 北京乾达源科技有限公司 | CCD (Charge Coupled Device) scattering and refracting spectrum method-based device for analyzing tiny oil and pollution degree of water online |
| CN115266618A (en) * | 2022-07-12 | 2022-11-01 | 宁波新芝生物科技股份有限公司 | Optical system for synchronously detecting full-wavelength absorbance of microporous plate sample |
-
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- 2023-01-05 CN CN202310014798.4A patent/CN115747036B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1800340A (en) * | 2004-12-31 | 2006-07-12 | 王衍淞 | Illumination method using when obtaining culture dish colony image |
| CN103616383A (en) * | 2013-12-02 | 2014-03-05 | 江苏大学 | Method for quantitatively detecting stability of flora structure in batch food fermentation process |
| CN105651679A (en) * | 2016-02-04 | 2016-06-08 | 华中农业大学 | Method for quickly classifying bacterial colonies on culture medium on basis of hyperspectral imaging technology |
| CN108918444A (en) * | 2018-07-23 | 2018-11-30 | 哈尔滨理工大学 | The detection method of Escherichia coli in cow's milk based on ultraviolet-visible light spectral technology |
| CN114839145A (en) * | 2022-05-07 | 2022-08-02 | 福建福晶科技股份有限公司 | Laser damage analysis test instrument |
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